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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR1H2

Z-value: 0.61

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Transcription factors associated with NR1H2

Gene Symbol Gene ID Gene Info
NR1H2
ENSG00000131408.9 nuclear receptor subfamily 1 group H member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H2hg19_v2_chr19_+_50879705_50879775-0.202.8e-01Click!

Activity profile of NR1H2 motif

Sorted Z-values of NR1H2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_234104079 2.90 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr7_-_76247617 2.35 ENST00000441393.1
POMZP3
POM121 and ZP3 fusion
chr2_+_113735575 1.92 ENST00000376489.2
ENST00000259205.4
IL36G
interleukin 36, gamma
chr22_+_30792846 1.69 ENST00000312932.9
ENST00000428195.1
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr1_-_113478603 1.17 ENST00000443580.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr17_-_76183111 1.14 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1
thymidine kinase 1, soluble
chr11_+_844406 1.04 ENST00000397404.1
TSPAN4
tetraspanin 4
chr1_+_10290822 0.91 ENST00000377083.1
KIF1B
kinesin family member 1B
chr6_-_144385698 0.87 ENST00000444202.1
ENST00000437412.1
PLAGL1
pleiomorphic adenoma gene-like 1
chr9_-_107690420 0.77 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr4_-_39033963 0.76 ENST00000381938.3
TMEM156
transmembrane protein 156
chr1_-_237167718 0.72 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr10_-_70287172 0.71 ENST00000539557.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr11_+_86748998 0.70 ENST00000525018.1
ENST00000355734.4
TMEM135
transmembrane protein 135
chr1_-_161207953 0.65 ENST00000367982.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr16_+_88704978 0.64 ENST00000244241.4
IL17C
interleukin 17C
chr15_-_63674218 0.64 ENST00000178638.3
CA12
carbonic anhydrase XII
chr12_+_22778116 0.61 ENST00000538218.1
ETNK1
ethanolamine kinase 1
chr1_-_161208013 0.61 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr4_+_5526883 0.60 ENST00000195455.2
C4orf6
chromosome 4 open reading frame 6
chr3_+_39371255 0.59 ENST00000414803.1
ENST00000545843.1
CCR8
chemokine (C-C motif) receptor 8
chr7_+_142031986 0.58 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr16_-_2205352 0.57 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr7_+_153584166 0.56 ENST00000404039.1
DPP6
dipeptidyl-peptidase 6
chr7_+_2687173 0.54 ENST00000403167.1
TTYH3
tweety family member 3
chr4_-_39034542 0.54 ENST00000344606.6
TMEM156
transmembrane protein 156
chr3_+_39371191 0.53 ENST00000326306.4
CCR8
chemokine (C-C motif) receptor 8
chr8_+_27182862 0.51 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr8_+_27183033 0.50 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr1_+_169337172 0.50 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1
basic leucine zipper nuclear factor 1
chr22_+_36113919 0.48 ENST00000249044.2
APOL5
apolipoprotein L, 5
chr4_+_57371509 0.47 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chr7_+_100136811 0.46 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr19_+_17865011 0.45 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
FCHO1
FCH domain only 1
chr19_+_58545434 0.45 ENST00000282326.1
ENST00000601162.1
ZSCAN1
zinc finger and SCAN domain containing 1
chr6_+_30687978 0.45 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr15_+_91473403 0.45 ENST00000394275.2
UNC45A
unc-45 homolog A (C. elegans)
chr9_+_135937365 0.45 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr1_-_161207986 0.44 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr21_-_46340807 0.43 ENST00000397846.3
ENST00000524251.1
ENST00000522688.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_+_87595433 0.43 ENST00000469312.2
ENST00000490006.2
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr8_+_38065104 0.43 ENST00000521311.1
BAG4
BCL2-associated athanogene 4
chr16_+_12058961 0.43 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr4_+_5527117 0.42 ENST00000505296.1
C4orf6
chromosome 4 open reading frame 6
chr8_-_124749609 0.42 ENST00000262219.6
ENST00000419625.1
ANXA13
annexin A13
chr19_-_2042065 0.42 ENST00000591588.1
ENST00000591142.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr3_-_49893958 0.41 ENST00000482243.1
ENST00000331456.2
ENST00000469027.1
TRAIP
TRAF interacting protein
chr14_-_102976135 0.41 ENST00000560748.1
ANKRD9
ankyrin repeat domain 9
chr6_-_167571817 0.41 ENST00000366834.1
GPR31
G protein-coupled receptor 31
chr20_-_48747662 0.41 ENST00000371656.2
TMEM189
transmembrane protein 189
chrX_+_21874105 0.41 ENST00000429584.2
YY2
YY2 transcription factor
chr19_-_6670128 0.41 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr5_-_138862326 0.40 ENST00000330794.4
TMEM173
transmembrane protein 173
chr12_-_113841678 0.38 ENST00000552280.1
ENST00000257549.4
SDS
serine dehydratase
chr15_+_43663257 0.38 ENST00000260383.7
ENST00000564079.1
TUBGCP4
tubulin, gamma complex associated protein 4
chr14_-_77787198 0.37 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr3_-_195938256 0.37 ENST00000296326.3
ZDHHC19
zinc finger, DHHC-type containing 19
chr7_+_45067265 0.37 ENST00000474617.1
CCM2
cerebral cavernous malformation 2
chr20_+_43343517 0.37 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr5_-_82969405 0.36 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr20_+_43343886 0.35 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr22_-_23974506 0.35 ENST00000317749.5
C22orf43
chromosome 22 open reading frame 43
chr11_+_119039414 0.35 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLRX1
NLR family member X1
chr3_+_46921732 0.34 ENST00000418619.1
PTH1R
parathyroid hormone 1 receptor
chr3_-_51994694 0.34 ENST00000395014.2
PCBP4
poly(rC) binding protein 4
chr1_-_9129895 0.33 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr9_-_86955657 0.31 ENST00000537648.1
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr11_+_67171391 0.31 ENST00000312390.5
TBC1D10C
TBC1 domain family, member 10C
chr13_-_33112956 0.31 ENST00000505213.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr7_-_56160625 0.31 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr19_-_46296011 0.30 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr2_+_73441350 0.29 ENST00000389501.4
SMYD5
SMYD family member 5
chr19_+_7968728 0.29 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
MAP2K7
mitogen-activated protein kinase kinase 7
chr14_+_77787227 0.29 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1
glutathione S-transferase zeta 1
chr19_+_38924316 0.29 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
RYR1
ryanodine receptor 1 (skeletal)
chr17_-_49198216 0.28 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chr20_-_39928756 0.28 ENST00000432768.2
ZHX3
zinc fingers and homeoboxes 3
chr2_+_223725652 0.28 ENST00000357430.3
ENST00000392066.3
ACSL3
acyl-CoA synthetase long-chain family member 3
chr19_+_15752088 0.28 ENST00000585846.1
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr16_-_31147020 0.28 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr6_+_36097992 0.27 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr14_-_102976091 0.27 ENST00000286918.4
ANKRD9
ankyrin repeat domain 9
chr11_+_86748863 0.27 ENST00000340353.7
TMEM135
transmembrane protein 135
chr2_+_238877424 0.26 ENST00000434655.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr2_+_168043793 0.25 ENST00000409273.1
ENST00000409605.1
XIRP2
xin actin-binding repeat containing 2
chr19_+_33071974 0.25 ENST00000590247.2
ENST00000419343.3
ENST00000592786.1
ENST00000379316.3
PDCD5
programmed cell death 5
chr22_+_19118321 0.25 ENST00000399635.2
TSSK2
testis-specific serine kinase 2
chr2_-_74699770 0.24 ENST00000409710.1
MRPL53
mitochondrial ribosomal protein L53
chr9_+_34179003 0.24 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
UBAP1
ubiquitin associated protein 1
chr19_+_1026298 0.24 ENST00000263097.4
CNN2
calponin 2
chr19_+_2977444 0.24 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr11_+_67171358 0.23 ENST00000526387.1
TBC1D10C
TBC1 domain family, member 10C
chr6_+_31674639 0.23 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
LY6G6F
MEGT1
lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr12_-_118797475 0.22 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr19_-_38747172 0.22 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr12_+_100594557 0.22 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr7_-_56160666 0.22 ENST00000297373.2
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr22_-_24096630 0.21 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr22_-_36031181 0.21 ENST00000594060.1
AL049747.1
AL049747.1
chr17_+_77019030 0.21 ENST00000580454.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr1_+_87458692 0.20 ENST00000370548.2
ENST00000356813.4
RP5-1052I5.2
HS2ST1
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr11_+_64692143 0.20 ENST00000164133.2
ENST00000532850.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr2_-_165697920 0.19 ENST00000342193.4
ENST00000375458.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr8_+_142402089 0.19 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr20_+_30028322 0.19 ENST00000376309.3
DEFB123
defensin, beta 123
chr1_+_23037323 0.19 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2
EPH receptor B2
chr15_+_83776137 0.19 ENST00000322019.9
TM6SF1
transmembrane 6 superfamily member 1
chr8_-_48651648 0.18 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr14_-_73925225 0.18 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
NUMB
numb homolog (Drosophila)
chr22_-_38577782 0.18 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr20_+_44330651 0.18 ENST00000305479.2
WFDC13
WAP four-disulfide core domain 13
chr19_+_34287174 0.18 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr11_-_68518910 0.18 ENST00000544963.1
ENST00000443940.2
MTL5
metallothionein-like 5, testis-specific (tesmin)
chr1_-_13115578 0.17 ENST00000414205.2
PRAMEF6
PRAME family member 6
chr10_+_101491968 0.17 ENST00000370476.5
ENST00000370472.4
CUTC
cutC copper transporter
chr19_+_1077393 0.16 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr1_-_40098672 0.15 ENST00000535435.1
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chrX_-_9001116 0.15 ENST00000428477.1
FAM9B
family with sequence similarity 9, member B
chr12_+_120972606 0.15 ENST00000413266.2
RNF10
ring finger protein 10
chr22_-_38577731 0.15 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr13_-_33112899 0.15 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
N4BP2L2
NEDD4 binding protein 2-like 2
chr3_+_139062838 0.15 ENST00000310776.4
ENST00000465056.1
ENST00000465373.1
MRPS22
mitochondrial ribosomal protein S22
chr12_-_120765565 0.15 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr20_-_4721314 0.15 ENST00000418528.1
ENST00000326539.2
ENST00000423718.2
PRNT
prion protein (testis specific)
chr19_+_16254488 0.15 ENST00000588246.1
ENST00000593031.1
HSH2D
hematopoietic SH2 domain containing
chr12_+_52282001 0.15 ENST00000340970.4
ANKRD33
ankyrin repeat domain 33
chrX_+_52240504 0.14 ENST00000399805.2
XAGE1B
X antigen family, member 1B
chr19_+_44220247 0.14 ENST00000596627.1
IRGC
immunity-related GTPase family, cinema
chr17_+_77018896 0.14 ENST00000578229.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_+_77774897 0.14 ENST00000281030.2
THRSP
thyroid hormone responsive
chr17_-_2169425 0.14 ENST00000570606.1
ENST00000354901.4
SMG6
SMG6 nonsense mediated mRNA decay factor
chr12_-_322821 0.14 ENST00000359674.4
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr20_+_57556263 0.14 ENST00000602795.1
ENST00000344018.3
NELFCD
negative elongation factor complex member C/D
chr4_-_80247162 0.14 ENST00000286794.4
NAA11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chrX_-_9001351 0.14 ENST00000362066.3
FAM9B
family with sequence similarity 9, member B
chr6_-_31763408 0.13 ENST00000444930.2
VARS
valyl-tRNA synthetase
chr2_-_114036488 0.13 ENST00000263335.7
ENST00000397647.3
ENST00000348715.5
ENST00000429538.3
PAX8
paired box 8
chr6_-_31763721 0.13 ENST00000375663.3
VARS
valyl-tRNA synthetase
chr19_-_36391434 0.13 ENST00000396901.1
ENST00000585925.1
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr12_-_56694142 0.13 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr5_+_76145826 0.12 ENST00000513010.1
S100Z
S100 calcium binding protein Z
chr22_-_24096562 0.12 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr14_-_94970559 0.12 ENST00000556881.1
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr17_+_76142434 0.12 ENST00000340363.5
ENST00000586999.1
C17orf99
chromosome 17 open reading frame 99
chr19_+_3224700 0.12 ENST00000292672.2
ENST00000541430.2
CELF5
CUGBP, Elav-like family member 5
chr15_+_67835517 0.11 ENST00000395476.2
MAP2K5
mitogen-activated protein kinase kinase 5
chr3_+_9404526 0.11 ENST00000452837.2
ENST00000417036.1
ENST00000419437.1
ENST00000345094.3
ENST00000515662.2
THUMPD3
THUMP domain containing 3
chr9_+_95726243 0.11 ENST00000416701.2
FGD3
FYVE, RhoGEF and PH domain containing 3
chr19_-_49121054 0.11 ENST00000546623.1
ENST00000084795.5
RPL18
ribosomal protein L18
chr12_+_52281744 0.11 ENST00000301190.6
ENST00000538991.1
ANKRD33
ankyrin repeat domain 33
chr19_+_15751689 0.10 ENST00000586182.2
ENST00000591058.1
ENST00000221307.8
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr19_-_58427944 0.10 ENST00000312026.5
ENST00000536263.1
ENST00000598629.1
ENST00000595559.1
ENST00000597515.1
ENST00000599251.1
ENST00000598526.1
ZNF417
zinc finger protein 417
chr5_+_76145920 0.10 ENST00000317593.4
S100Z
S100 calcium binding protein Z
chr19_-_22193706 0.10 ENST00000597040.1
ZNF208
zinc finger protein 208
chr1_+_10459111 0.10 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
PGD
phosphogluconate dehydrogenase
chr6_-_2972075 0.10 ENST00000335686.5
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr2_+_145425573 0.10 ENST00000600064.1
ENST00000597670.1
ENST00000414256.1
ENST00000599187.1
ENST00000451774.1
ENST00000599072.1
ENST00000596589.1
ENST00000597893.1
TEX41
testis expressed 41 (non-protein coding)
chr19_+_15904761 0.10 ENST00000308940.8
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr20_+_34680620 0.10 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_-_9714644 0.10 ENST00000377320.3
C1orf200
chromosome 1 open reading frame 200
chr9_-_86955598 0.10 ENST00000376238.4
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr19_+_17622415 0.10 ENST00000252603.2
ENST00000600923.1
PGLS
6-phosphogluconolactonase
chr19_+_57631411 0.10 ENST00000254181.4
ENST00000600940.1
USP29
ubiquitin specific peptidase 29
chr7_-_74489609 0.09 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
WBSCR16
Williams-Beuren syndrome chromosome region 16
chr17_+_78152274 0.09 ENST00000344227.2
ENST00000570421.1
CARD14
caspase recruitment domain family, member 14
chr17_-_35716019 0.09 ENST00000591148.1
ENST00000394406.2
ENST00000394403.1
ACACA
acetyl-CoA carboxylase alpha
chr9_+_95736758 0.09 ENST00000337352.6
FGD3
FYVE, RhoGEF and PH domain containing 3
chr12_+_22778009 0.09 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chr5_-_180671172 0.09 ENST00000512805.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr4_+_183164574 0.09 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr1_+_201755452 0.09 ENST00000438083.1
NAV1
neuron navigator 1
chr2_+_228029281 0.09 ENST00000396578.3
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr22_-_26875345 0.09 ENST00000398141.1
HPS4
Hermansky-Pudlak syndrome 4
chr15_+_45021183 0.08 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr1_+_150337100 0.08 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr17_-_79604075 0.08 ENST00000374747.5
ENST00000539314.1
ENST00000331134.6
NPLOC4
nuclear protein localization 4 homolog (S. cerevisiae)
chr17_+_66243715 0.08 ENST00000359904.3
AMZ2
archaelysin family metallopeptidase 2
chr15_-_83837983 0.07 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr12_-_322504 0.07 ENST00000424061.2
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr8_-_93115445 0.07 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_155829191 0.07 ENST00000437809.1
GON4L
gon-4-like (C. elegans)
chr1_+_22962948 0.06 ENST00000374642.3
C1QA
complement component 1, q subcomponent, A chain
chr16_+_56995854 0.06 ENST00000566128.1
CETP
cholesteryl ester transfer protein, plasma
chr11_+_10326612 0.06 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr9_-_130829588 0.06 ENST00000373078.4
NAIF1
nuclear apoptosis inducing factor 1
chr9_-_36400213 0.05 ENST00000259605.6
ENST00000353739.4
RNF38
ring finger protein 38
chr14_-_22005062 0.05 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr1_+_87595542 0.05 ENST00000461990.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr11_-_82611448 0.05 ENST00000393399.2
ENST00000313010.3
PRCP
prolylcarboxypeptidase (angiotensinase C)
chrX_+_1455478 0.05 ENST00000331035.4
IL3RA
interleukin 3 receptor, alpha (low affinity)
chr4_-_681114 0.05 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr4_-_71705027 0.05 ENST00000545193.1
GRSF1
G-rich RNA sequence binding factor 1
chr3_-_127309879 0.04 ENST00000489960.1
ENST00000490290.1
TPRA1
transmembrane protein, adipocyte asscociated 1
chr20_-_44600810 0.04 ENST00000322927.2
ENST00000426788.1
ZNF335
zinc finger protein 335
chr14_-_59950724 0.04 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr17_-_42580738 0.04 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
GPATCH8
G patch domain containing 8
chr8_-_121457332 0.04 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr1_+_87595497 0.04 ENST00000471417.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chrX_+_102631248 0.04 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr21_-_35281399 0.03 ENST00000418933.1
ATP5O
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 2.4 GO:0035803 egg coat formation(GO:0035803)
0.4 1.2 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.3 1.1 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.3 1.0 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 0.9 GO:1904647 response to rotenone(GO:1904647)
0.2 0.8 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.6 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.6 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.4 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.4 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.4 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.2 GO:0030860 neuroblast division in subventricular zone(GO:0021849) regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 0.6 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.4 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.3 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.4 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.3 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.7 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.9 GO:0032094 response to food(GO:0032094)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.2 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.2 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.4 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0002155 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 1.7 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.0 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.4 GO:0034694 response to prostaglandin(GO:0034694)
0.0 0.1 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.3 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.9 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.0 GO:0071159 NF-kappaB complex(GO:0071159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 1.7 GO:0008431 vitamin E binding(GO:0008431)
0.4 1.2 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.4 1.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.3 1.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 1.7 GO:0004882 androgen receptor activity(GO:0004882)
0.3 0.8 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 2.4 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 0.4 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.4 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.5 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.0 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis