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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR1H4

Z-value: 0.61

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Transcription factors associated with NR1H4

Gene Symbol Gene ID Gene Info
NR1H4
ENSG00000012504.9 nuclear receptor subfamily 1 group H member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H4hg19_v2_chr12_+_100897130_1008972310.365.0e-02Click!

Activity profile of NR1H4 motif

Sorted Z-values of NR1H4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_106449862 3.21 ENST00000372453.3
ENST00000535523.1
PIH1D3
PIH1 domain containing 3
chr9_-_34381536 3.01 ENST00000379126.3
ENST00000379127.1
ENST00000379133.3
C9orf24
chromosome 9 open reading frame 24
chr9_-_34381511 2.92 ENST00000379124.1
C9orf24
chromosome 9 open reading frame 24
chr3_-_50383096 2.81 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr14_-_65769392 2.53 ENST00000555736.1
CTD-2509G16.5
CTD-2509G16.5
chr9_-_138391692 2.21 ENST00000429260.2
C9orf116
chromosome 9 open reading frame 116
chrX_+_152338301 2.01 ENST00000453825.2
PNMA6A
paraneoplastic Ma antigen family member 6A
chr13_+_31506818 1.86 ENST00000380473.3
TEX26
testis expressed 26
chr7_-_131241361 1.53 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr5_-_16509101 1.34 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr19_-_50311896 1.27 ENST00000529634.2
FUZ
fuzzy planar cell polarity protein
chr19_+_50706866 1.19 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chr20_-_62462566 1.18 ENST00000245663.4
ENST00000302995.2
ZBTB46
zinc finger and BTB domain containing 46
chr18_+_3449330 1.08 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr1_+_162351503 1.07 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr5_-_139944196 1.07 ENST00000357560.4
APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr5_-_139943830 0.99 ENST00000412920.3
ENST00000511201.2
ENST00000356738.2
ENST00000354402.5
ENST00000358580.5
ENST00000508496.2
APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr16_-_67700594 0.85 ENST00000602644.1
ENST00000243878.4
ENKD1
enkurin domain containing 1
chr1_+_151483855 0.83 ENST00000427934.2
ENST00000271636.7
CGN
cingulin
chr19_+_35629702 0.77 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr14_-_21492113 0.74 ENST00000554094.1
NDRG2
NDRG family member 2
chr14_-_21492251 0.74 ENST00000554398.1
NDRG2
NDRG family member 2
chr11_+_45868957 0.72 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr14_-_25103388 0.70 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr11_-_116663127 0.70 ENST00000433069.1
ENST00000542499.1
APOA5
apolipoprotein A-V
chrX_-_106449656 0.69 ENST00000372466.4
ENST00000421752.1
ENST00000372461.3
NUP62CL
nucleoporin 62kDa C-terminal like
chr19_+_10563567 0.69 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr8_-_101321584 0.68 ENST00000523167.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr3_+_186560462 0.64 ENST00000412955.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr3_+_186560476 0.63 ENST00000320741.2
ENST00000444204.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr20_+_62369623 0.61 ENST00000467211.1
RP4-583P15.14
RP4-583P15.14
chr14_-_25103472 0.61 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr7_+_94139105 0.59 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr12_-_7281469 0.57 ENST00000542370.1
ENST00000266560.3
RBP5
retinol binding protein 5, cellular
chr3_+_118866222 0.54 ENST00000490594.1
RP11-484M3.5
Uncharacterized protein
chr17_-_46035187 0.54 ENST00000300557.2
PRR15L
proline rich 15-like
chr14_-_23755297 0.52 ENST00000357460.5
HOMEZ
homeobox and leucine zipper encoding
chr3_-_160117301 0.50 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr12_+_6898638 0.49 ENST00000011653.4
CD4
CD4 molecule
chr6_-_49681235 0.49 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr3_+_122296443 0.46 ENST00000464300.2
PARP15
poly (ADP-ribose) polymerase family, member 15
chr4_+_25915896 0.45 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr4_+_25915822 0.43 ENST00000506197.2
SMIM20
small integral membrane protein 20
chr15_+_65337708 0.43 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr3_+_54157480 0.42 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr17_-_53809473 0.41 ENST00000575734.1
TMEM100
transmembrane protein 100
chr11_+_7534999 0.40 ENST00000528947.1
ENST00000299492.4
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_+_133450365 0.38 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr12_+_57914742 0.38 ENST00000551351.1
MBD6
methyl-CpG binding domain protein 6
chr17_+_7533439 0.37 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr7_+_94536898 0.36 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr22_+_45072958 0.36 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr19_-_44860820 0.35 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
ZNF112
zinc finger protein 112
chr3_+_184055240 0.35 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr22_+_45072925 0.35 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr2_-_207024233 0.35 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_-_219433014 0.33 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37
chr12_-_56727676 0.32 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr8_+_110346546 0.32 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2
enhancer of yellow 2 homolog (Drosophila)
chr12_-_56727487 0.32 ENST00000548043.1
ENST00000425394.2
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr5_+_139927213 0.31 ENST00000310331.2
EIF4EBP3
eukaryotic translation initiation factor 4E binding protein 3
chr5_+_140588269 0.31 ENST00000541609.1
ENST00000239450.2
PCDHB12
protocadherin beta 12
chr12_+_109273806 0.31 ENST00000228476.3
ENST00000547768.1
DAO
D-amino-acid oxidase
chr12_-_46121554 0.30 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr22_+_32149927 0.29 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEPDC5
DEP domain containing 5
chr9_+_35042205 0.29 ENST00000312292.5
ENST00000378745.3
C9orf131
chromosome 9 open reading frame 131
chr12_+_52306113 0.29 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1
activin A receptor type II-like 1
chr1_+_1334895 0.27 ENST00000448629.2
ENST00000444362.1
RP4-758J18.2
HCG20425, isoform CRA_a; Uncharacterized protein; cDNA FLJ53815
chr19_-_51893827 0.27 ENST00000574814.1
CTD-2616J11.4
chromosome 19 open reading frame 84
chr1_-_36789755 0.26 ENST00000270824.1
EVA1B
eva-1 homolog B (C. elegans)
chr19_-_48867291 0.26 ENST00000435956.3
TMEM143
transmembrane protein 143
chr11_-_4414880 0.26 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr2_-_74780176 0.25 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr9_-_34372830 0.25 ENST00000379142.3
KIAA1161
KIAA1161
chr19_-_48867171 0.25 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr1_+_36789335 0.24 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr9_-_44402427 0.24 ENST00000540551.1
BX088651.1
LOC100126582 protein; Uncharacterized protein
chr2_+_179345173 0.23 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr17_-_9940058 0.23 ENST00000585266.1
GAS7
growth arrest-specific 7
chr11_-_7041466 0.22 ENST00000536068.1
ENST00000278314.4
ZNF214
zinc finger protein 214
chr13_+_27844464 0.22 ENST00000241463.4
RASL11A
RAS-like, family 11, member A
chrX_-_132549506 0.22 ENST00000370828.3
GPC4
glypican 4
chr16_+_2014941 0.21 ENST00000531523.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr4_+_26322409 0.21 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chrX_-_47930980 0.21 ENST00000442455.3
ENST00000428686.1
ENST00000276054.4
ZNF630
zinc finger protein 630
chr3_+_49058444 0.20 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr6_-_106773610 0.20 ENST00000369076.3
ENST00000369070.1
ATG5
autophagy related 5
chr1_-_1334685 0.20 ENST00000400809.3
ENST00000408918.4
CCNL2
cyclin L2
chr11_-_118305921 0.20 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr6_+_127588020 0.19 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146
ring finger protein 146
chr16_-_69166460 0.19 ENST00000523421.1
ENST00000448552.2
ENST00000306585.6
ENST00000567763.1
ENST00000522497.1
ENST00000522091.1
ENST00000519520.1
CHTF8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr22_-_21387127 0.18 ENST00000426145.1
SLC7A4
solute carrier family 7, member 4
chr2_-_182545603 0.18 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr6_-_33771757 0.17 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
MLN
motilin
chr1_+_36690011 0.17 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
THRAP3
thyroid hormone receptor associated protein 3
chr1_+_14026722 0.17 ENST00000376048.5
PRDM2
PR domain containing 2, with ZNF domain
chr6_-_106773491 0.17 ENST00000360666.4
ATG5
autophagy related 5
chr11_-_71639670 0.16 ENST00000533047.1
ENST00000529844.1
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr16_-_1429627 0.16 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr6_+_107349392 0.16 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
C6orf203
chromosome 6 open reading frame 203
chr17_-_7145475 0.16 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr5_+_138629337 0.16 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
MATR3
matrin 3
chr3_+_14989186 0.16 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr2_+_219433281 0.15 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr1_+_25598989 0.15 ENST00000454452.2
RHD
Rh blood group, D antigen
chr5_+_140579162 0.15 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr11_+_64073699 0.15 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr9_+_74526532 0.15 ENST00000486911.2
C9orf85
chromosome 9 open reading frame 85
chr5_+_149569520 0.15 ENST00000230671.2
ENST00000524041.1
SLC6A7
solute carrier family 6 (neurotransmitter transporter), member 7
chr4_-_143395551 0.15 ENST00000507861.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_-_37499726 0.14 ENST00000373091.3
ENST00000373093.4
GRIK3
glutamate receptor, ionotropic, kainate 3
chr1_+_26560676 0.14 ENST00000451429.2
ENST00000252992.4
CEP85
centrosomal protein 85kDa
chr17_+_36858694 0.14 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr5_+_138629417 0.13 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3
matrin 3
chr22_+_30163340 0.13 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr19_-_18385246 0.13 ENST00000608950.1
ENST00000600328.3
ENST00000600359.3
ENST00000392413.4
KIAA1683
KIAA1683
chr8_-_116504448 0.12 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr2_-_178937478 0.12 ENST00000286063.6
PDE11A
phosphodiesterase 11A
chr5_+_138629389 0.12 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
MATR3
matrin 3
chr17_+_41177220 0.12 ENST00000587250.2
ENST00000544533.1
RND2
Rho family GTPase 2
chr1_+_178482212 0.11 ENST00000319416.2
ENST00000258298.2
ENST00000367643.3
ENST00000367642.3
TEX35
testis expressed 35
chr5_+_162930114 0.11 ENST00000280969.5
MAT2B
methionine adenosyltransferase II, beta
chr3_-_123512688 0.11 ENST00000475616.1
MYLK
myosin light chain kinase
chr5_+_139944396 0.11 ENST00000514199.1
SLC35A4
solute carrier family 35, member A4
chr1_+_44412577 0.11 ENST00000372343.3
IPO13
importin 13
chr6_-_106773291 0.11 ENST00000343245.3
ATG5
autophagy related 5
chr16_+_67700673 0.11 ENST00000403458.4
ENST00000602365.1
C16orf86
chromosome 16 open reading frame 86
chr19_+_1071203 0.11 ENST00000543365.1
HMHA1
histocompatibility (minor) HA-1
chr20_+_30640004 0.11 ENST00000520553.1
ENST00000518730.1
ENST00000375852.2
HCK
hemopoietic cell kinase
chr8_+_9046503 0.10 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr12_+_120875910 0.10 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr22_-_20104700 0.10 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
TRMT2A
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr4_-_171011084 0.10 ENST00000337664.4
AADAT
aminoadipate aminotransferase
chr1_+_202317855 0.10 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr10_-_95360983 0.10 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr16_+_66995121 0.10 ENST00000303334.4
CES3
carboxylesterase 3
chr1_+_33207381 0.10 ENST00000401073.2
KIAA1522
KIAA1522
chr19_-_51054299 0.10 ENST00000599957.1
LRRC4B
leucine rich repeat containing 4B
chr17_-_26879567 0.10 ENST00000581945.1
ENST00000444148.1
ENST00000301032.4
ENST00000335765.4
UNC119
unc-119 homolog (C. elegans)
chr19_+_10197463 0.10 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr4_-_171011323 0.09 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
AADAT
aminoadipate aminotransferase
chr5_-_33892204 0.09 ENST00000504830.1
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chrX_-_152989798 0.09 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31
B-cell receptor-associated protein 31
chr16_+_66995144 0.09 ENST00000394037.1
CES3
carboxylesterase 3
chr19_-_10613421 0.09 ENST00000393623.2
KEAP1
kelch-like ECH-associated protein 1
chr17_-_43568062 0.09 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr15_-_75932528 0.09 ENST00000403490.1
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr16_+_70258261 0.09 ENST00000594734.1
FKSG63
FKSG63
chr6_+_127587755 0.08 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146
ring finger protein 146
chr12_+_120875887 0.08 ENST00000229379.2
COX6A1
cytochrome c oxidase subunit VIa polypeptide 1
chr6_+_44126545 0.08 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
CAPN11
calpain 11
chr1_+_33231268 0.07 ENST00000373480.1
KIAA1522
KIAA1522
chr16_-_30537839 0.07 ENST00000380412.5
ZNF768
zinc finger protein 768
chr14_+_24025194 0.07 ENST00000404535.3
ENST00000288014.6
THTPA
thiamine triphosphatase
chr5_+_131593364 0.07 ENST00000253754.3
ENST00000379018.3
PDLIM4
PDZ and LIM domain 4
chr17_+_17685422 0.07 ENST00000395774.1
RAI1
retinoic acid induced 1
chr17_+_34136459 0.07 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr1_+_178482262 0.07 ENST00000367641.3
ENST00000367639.1
TEX35
testis expressed 35
chr17_-_27038765 0.06 ENST00000581289.1
ENST00000301039.2
PROCA1
protein interacting with cyclin A1
chr14_-_21945057 0.06 ENST00000397762.1
RAB2B
RAB2B, member RAS oncogene family
chr5_+_139944024 0.06 ENST00000323146.3
SLC35A4
solute carrier family 35, member A4
chr11_+_67250490 0.06 ENST00000528641.2
ENST00000279146.3
AIP
aryl hydrocarbon receptor interacting protein
chr11_-_65430251 0.06 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr14_-_74892805 0.06 ENST00000331628.3
ENST00000554953.1
SYNDIG1L
synapse differentiation inducing 1-like
chr17_-_73257667 0.06 ENST00000538886.1
ENST00000580799.1
ENST00000351904.7
ENST00000537686.1
GGA3
golgi-associated, gamma adaptin ear containing, ARF binding protein 3
chr19_+_36142147 0.06 ENST00000590618.1
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr9_-_96215822 0.05 ENST00000375412.5
FAM120AOS
family with sequence similarity 120A opposite strand
chr10_-_49701686 0.05 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr4_+_123073464 0.05 ENST00000264501.4
KIAA1109
KIAA1109
chr12_-_58135903 0.05 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr21_-_46515493 0.05 ENST00000600921.1
PRED57
HCG401283; PRED57 protein; Uncharacterized protein
chr19_-_35626104 0.05 ENST00000310123.3
ENST00000392225.3
LGI4
leucine-rich repeat LGI family, member 4
chr5_+_137419581 0.05 ENST00000506684.1
ENST00000504809.1
ENST00000398754.1
WNT8A
wingless-type MMTV integration site family, member 8A
chr9_-_35958151 0.05 ENST00000341959.2
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr3_-_58652523 0.05 ENST00000489857.1
ENST00000358781.2
FAM3D
family with sequence similarity 3, member D
chr1_-_160040038 0.05 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr22_+_20104947 0.04 ENST00000402752.1
RANBP1
RAN binding protein 1
chr11_+_7273181 0.04 ENST00000318881.6
SYT9
synaptotagmin IX
chr17_-_37764128 0.04 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr3_-_120461378 0.04 ENST00000273375.3
RABL3
RAB, member of RAS oncogene family-like 3
chr11_-_71639480 0.04 ENST00000529513.1
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr5_+_138629628 0.04 ENST00000508689.1
ENST00000514528.1
MATR3
matrin 3
chrX_-_153141302 0.03 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM
L1 cell adhesion molecule
chr3_-_38071122 0.03 ENST00000334661.4
PLCD1
phospholipase C, delta 1
chr22_+_22786288 0.03 ENST00000390301.2
IGLV1-36
immunoglobulin lambda variable 1-36
chrX_+_103031421 0.03 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
PLP1
proteolipid protein 1
chr3_+_52489503 0.03 ENST00000345716.4
NISCH
nischarin
chr12_+_67663056 0.02 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr5_+_145317356 0.02 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr1_-_16539094 0.02 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr22_+_20105259 0.02 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr5_-_137878887 0.02 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr1_+_202317815 0.02 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr20_+_30639991 0.02 ENST00000534862.1
ENST00000538448.1
ENST00000375862.2
HCK
hemopoietic cell kinase
chr1_+_25599018 0.02 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD
Rh blood group, D antigen
chr4_+_41992489 0.02 ENST00000264451.7
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr17_-_2614927 0.02 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr11_+_67798114 0.01 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr11_-_62380199 0.01 ENST00000419857.1
ENST00000394773.2
EML3
echinoderm microtubule associated protein like 3
chr1_+_21766641 0.01 ENST00000342104.5
NBPF3
neuroblastoma breakpoint family, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0097018 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.4 1.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 1.3 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 0.7 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 2.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 1.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 3.2 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.7 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.1 1.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.8 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.4 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.5 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.1 1.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.5 GO:2000619 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.1 0.2 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.3 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.4 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.3 GO:0035912 dorsal aorta morphogenesis(GO:0035912)
0.0 0.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 1.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.7 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0097513 myosin II filament(GO:0097513)
0.2 1.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.6 GO:0031251 PAN complex(GO:0031251)
0.1 2.8 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.4 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0042627 chylomicron(GO:0042627)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0035473 lipase binding(GO:0035473) lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.6 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0005497 androgen binding(GO:0005497)
0.0 0.7 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0016918 retinal binding(GO:0016918)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 2.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 1.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling