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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR1I2

Z-value: 0.58

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Transcription factors associated with NR1I2

Gene Symbol Gene ID Gene Info
NR1I2
ENSG00000144852.12 nuclear receptor subfamily 1 group I member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I2hg19_v2_chr3_+_119499331_119499331,
hg19_v2_chr3_+_119501557_119501557		0.048.5e-01Click!

Activity profile of NR1I2 motif

Sorted Z-values of NR1I2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_94833642 1.34 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr20_-_52790512 1.27 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr1_+_218519577 0.96 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr2_+_30454390 0.90 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH
limb bud and heart development
chr4_-_120243545 0.78 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr20_+_3776371 0.78 ENST00000245960.5
CDC25B
cell division cycle 25B
chr11_-_111783595 0.78 ENST00000528628.1
CRYAB
crystallin, alpha B
chr20_+_3776936 0.74 ENST00000439880.2
CDC25B
cell division cycle 25B
chrX_+_135279179 0.73 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr2_-_235405168 0.68 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr9_+_33795533 0.66 ENST00000379405.3
PRSS3
protease, serine, 3
chr19_-_51472222 0.65 ENST00000376851.3
KLK6
kallikrein-related peptidase 6
chr15_-_81616446 0.63 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chrX_+_135278908 0.62 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr17_+_7942424 0.60 ENST00000573359.1
ALOX15B
arachidonate 15-lipoxygenase, type B
chr12_-_95510743 0.60 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr4_-_159094194 0.59 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr14_+_79746249 0.55 ENST00000428277.2
NRXN3
neurexin 3
chr1_+_74701062 0.55 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr19_+_35485682 0.50 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chrX_-_72299258 0.50 ENST00000453389.1
ENST00000373519.1
PABPC1L2A
poly(A) binding protein, cytoplasmic 1-like 2A
chr1_+_16083154 0.49 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr1_+_15479054 0.48 ENST00000376014.3
ENST00000451326.2
TMEM51
transmembrane protein 51
chr16_-_58328923 0.47 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54
protease, serine, 54
chr15_+_39873268 0.46 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr1_+_15479021 0.45 ENST00000428417.1
TMEM51
transmembrane protein 51
chr15_-_75017711 0.44 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr3_+_25469802 0.44 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr2_+_114256661 0.44 ENST00000306507.5
FOXD4L1
forkhead box D4-like 1
chr3_+_25469724 0.44 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr7_+_129007964 0.43 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr13_+_32605437 0.43 ENST00000380250.3
FRY
furry homolog (Drosophila)
chr8_+_102504651 0.43 ENST00000251808.3
ENST00000521085.1
GRHL2
grainyhead-like 2 (Drosophila)
chr11_+_117073850 0.43 ENST00000529622.1
TAGLN
transgelin
chr10_-_33625154 0.42 ENST00000265371.4
NRP1
neuropilin 1
chr20_+_62492566 0.42 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chrX_+_135251835 0.41 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr12_-_12715266 0.41 ENST00000228862.2
DUSP16
dual specificity phosphatase 16
chr9_-_118417 0.41 ENST00000382500.2
FOXD4
forkhead box D4
chr12_-_91576429 0.41 ENST00000552145.1
ENST00000546745.1
DCN
decorin
chr1_+_145209092 0.40 ENST00000362074.6
ENST00000344859.3
NOTCH2NL
notch 2 N-terminal like
chr1_-_197036364 0.38 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr15_-_89755034 0.37 ENST00000563254.1
RLBP1
retinaldehyde binding protein 1
chr12_-_91576561 0.37 ENST00000547568.2
ENST00000552962.1
DCN
decorin
chr2_-_192711968 0.37 ENST00000304141.4
SDPR
serum deprivation response
chr6_+_37897735 0.34 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr7_-_107642348 0.32 ENST00000393561.1
LAMB1
laminin, beta 1
chr12_-_96184533 0.32 ENST00000343702.4
ENST00000344911.4
NTN4
netrin 4
chr1_+_25944341 0.31 ENST00000263979.3
MAN1C1
mannosidase, alpha, class 1C, member 1
chr22_+_50354104 0.30 ENST00000360612.4
PIM3
pim-3 oncogene
chr8_-_121824374 0.29 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr7_+_134576151 0.29 ENST00000393118.2
CALD1
caldesmon 1
chr18_+_29027696 0.29 ENST00000257189.4
DSG3
desmoglein 3
chr11_+_62648336 0.29 ENST00000338663.7
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr12_-_91576750 0.29 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
DCN
decorin
chr6_-_134861089 0.28 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr6_+_12007963 0.28 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr14_+_73706308 0.28 ENST00000554301.1
ENST00000555445.1
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr12_-_100656134 0.28 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr7_+_112090483 0.27 ENST00000403825.3
ENST00000429071.1
IFRD1
interferon-related developmental regulator 1
chr22_+_25003626 0.27 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1
gamma-glutamyltransferase 1
chrX_-_15619076 0.27 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr11_+_62649158 0.27 ENST00000539891.1
ENST00000536981.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_-_149858227 0.25 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr7_+_110731062 0.25 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr19_+_39616410 0.25 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr15_+_59903975 0.25 ENST00000560585.1
ENST00000396065.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_+_41117770 0.25 ENST00000601032.1
LTBP4
latent transforming growth factor beta binding protein 4
chr6_+_12007897 0.25 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr5_+_78532003 0.24 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr16_-_2770216 0.24 ENST00000302641.3
PRSS27
protease, serine 27
chr15_-_43212836 0.24 ENST00000566931.1
ENST00000564431.1
ENST00000567274.1
TTBK2
tau tubulin kinase 2
chr22_+_21128167 0.24 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr16_+_11038403 0.23 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr5_+_66124590 0.23 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_-_234667504 0.23 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr10_+_112257596 0.23 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr20_+_43343886 0.23 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr20_-_13971255 0.23 ENST00000284951.5
ENST00000378072.5
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr1_-_120612240 0.22 ENST00000256646.2
NOTCH2
notch 2
chr18_-_67873078 0.22 ENST00000255674.6
RTTN
rotatin
chrX_-_30327495 0.22 ENST00000453287.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr17_-_7167279 0.22 ENST00000571932.2
CLDN7
claudin 7
chr1_-_152131703 0.22 ENST00000316073.3
RPTN
repetin
chr7_-_94285402 0.22 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr21_+_43823983 0.22 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr6_+_42896865 0.22 ENST00000372836.4
ENST00000394142.3
CNPY3
canopy FGF signaling regulator 3
chr20_-_46415297 0.21 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr9_+_17134980 0.21 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr3_+_37284824 0.21 ENST00000431105.1
GOLGA4
golgin A4
chr11_-_111794446 0.21 ENST00000527950.1
CRYAB
crystallin, alpha B
chr4_-_110723134 0.21 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr2_+_234627424 0.21 ENST00000373409.3
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
chr1_+_196912902 0.21 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr8_-_62559366 0.21 ENST00000522919.1
ASPH
aspartate beta-hydroxylase
chr4_-_111119804 0.21 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chrX_+_99839799 0.21 ENST00000373031.4
TNMD
tenomodulin
chr7_+_91875508 0.21 ENST00000265742.3
ANKIB1
ankyrin repeat and IBR domain containing 1
chrX_+_72223352 0.20 ENST00000373521.2
ENST00000538388.1
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chr16_-_4292071 0.20 ENST00000399609.3
SRL
sarcalumenin
chr19_+_54385439 0.20 ENST00000536044.1
ENST00000540413.1
ENST00000263431.3
ENST00000419486.1
PRKCG
protein kinase C, gamma
chr2_-_75426183 0.20 ENST00000409848.3
TACR1
tachykinin receptor 1
chr7_-_76247617 0.20 ENST00000441393.1
POMZP3
POM121 and ZP3 fusion
chr3_-_183735731 0.20 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr14_-_58893832 0.20 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr6_+_43738444 0.20 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr2_+_69240415 0.20 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr10_-_121296045 0.20 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr8_-_110986918 0.20 ENST00000297404.1
KCNV1
potassium channel, subfamily V, member 1
chr4_+_95972822 0.20 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr2_+_234621551 0.20 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr4_-_110723194 0.19 ENST00000394635.3
CFI
complement factor I
chr14_-_73493784 0.19 ENST00000553891.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr16_-_58328870 0.19 ENST00000543437.1
PRSS54
protease, serine, 54
chr5_+_218356 0.19 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr20_-_32700075 0.19 ENST00000374980.2
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr19_+_9251052 0.19 ENST00000247956.6
ENST00000360385.3
ZNF317
zinc finger protein 317
chr4_-_110723335 0.19 ENST00000394634.2
CFI
complement factor I
chr6_+_106546808 0.18 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr6_+_26273144 0.18 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr3_+_151451707 0.18 ENST00000356517.3
AADACL2
arylacetamide deacetylase-like 2
chr5_-_73937244 0.18 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr3_+_111630451 0.18 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr2_+_69240511 0.18 ENST00000409349.3
ANTXR1
anthrax toxin receptor 1
chr13_-_33112823 0.18 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chrX_+_49832231 0.18 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr5_-_127674883 0.18 ENST00000507835.1
FBN2
fibrillin 2
chr16_+_83986827 0.18 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr8_-_18666360 0.18 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr2_+_192141611 0.18 ENST00000392316.1
MYO1B
myosin IB
chr11_-_133715394 0.17 ENST00000299140.3
ENST00000532889.1
SPATA19
spermatogenesis associated 19
chr1_-_47069955 0.17 ENST00000341183.5
ENST00000496619.1
MKNK1
MAP kinase interacting serine/threonine kinase 1
chr22_-_38699003 0.17 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chr3_+_112930387 0.17 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr14_+_55034599 0.17 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr1_+_159557607 0.17 ENST00000255040.2
APCS
amyloid P component, serum
chr2_+_10560147 0.17 ENST00000422133.1
HPCAL1
hippocalcin-like 1
chr18_+_3466248 0.16 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr6_+_27782788 0.16 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr1_+_196788887 0.16 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr10_-_115904361 0.16 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr14_-_73493825 0.16 ENST00000318876.5
ENST00000556143.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr2_+_171034646 0.16 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr5_-_1801408 0.16 ENST00000505818.1
MRPL36
mitochondrial ribosomal protein L36
chr1_+_6266228 0.16 ENST00000377939.4
RNF207
ring finger protein 207
chr15_+_45028719 0.15 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
TRIM69
tripartite motif containing 69
chr17_+_1958388 0.15 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr3_+_8543561 0.15 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr18_+_21572737 0.15 ENST00000304621.6
TTC39C
tetratricopeptide repeat domain 39C
chr9_+_139981379 0.15 ENST00000371589.4
MAN1B1
mannosidase, alpha, class 1B, member 1
chr4_+_100495864 0.15 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chrX_+_64887512 0.15 ENST00000360270.5
MSN
moesin
chr5_+_34656569 0.15 ENST00000428746.2
RAI14
retinoic acid induced 14
chr5_+_149569520 0.15 ENST00000230671.2
ENST00000524041.1
SLC6A7
solute carrier family 6 (neurotransmitter transporter), member 7
chr1_+_25943959 0.15 ENST00000374332.4
MAN1C1
mannosidase, alpha, class 1C, member 1
chr15_+_45028520 0.15 ENST00000329464.4
TRIM69
tripartite motif containing 69
chr11_+_118478313 0.15 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr1_-_12908578 0.15 ENST00000317869.6
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chr7_-_100183742 0.15 ENST00000310300.6
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr14_+_77292715 0.15 ENST00000393774.3
ENST00000555189.1
ENST00000450042.2
C14orf166B
chromosome 14 open reading frame 166B
chr3_+_8543393 0.15 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_38206975 0.15 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr8_+_99956662 0.15 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr1_+_12538594 0.15 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr4_+_30721968 0.15 ENST00000361762.2
PCDH7
protocadherin 7
chr22_-_24641027 0.15 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
GGT5
gamma-glutamyltransferase 5
chr1_-_153521597 0.14 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr17_+_75137460 0.14 ENST00000587820.1
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr9_+_35829208 0.14 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chr1_-_40349106 0.14 ENST00000545233.1
ENST00000537440.1
ENST00000537223.1
ENST00000541099.1
ENST00000441669.2
ENST00000544981.1
ENST00000316891.5
ENST00000372818.1
TRIT1
tRNA isopentenyltransferase 1
chr2_+_223916862 0.14 ENST00000604125.1
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr6_+_126102292 0.14 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr10_-_25010795 0.14 ENST00000416305.1
ENST00000376410.2
ARHGAP21
Rho GTPase activating protein 21
chr1_+_46972668 0.14 ENST00000371956.4
ENST00000360032.3
DMBX1
diencephalon/mesencephalon homeobox 1
chr15_+_42696992 0.14 ENST00000561817.1
CAPN3
calpain 3, (p94)
chr1_-_149814478 0.14 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr1_-_144994909 0.14 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr7_+_135611542 0.14 ENST00000416501.1
AC015987.2
AC015987.2
chr5_-_180669236 0.14 ENST00000507756.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr6_-_132910877 0.14 ENST00000258034.2
TAAR5
trace amine associated receptor 5
chr7_-_95225768 0.14 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr1_+_110754094 0.14 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr5_-_149682447 0.13 ENST00000328668.7
ARSI
arylsulfatase family, member I
chr12_+_6494285 0.13 ENST00000541102.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr8_-_18541603 0.13 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr1_+_222817629 0.13 ENST00000340535.7
MIA3
melanoma inhibitory activity family, member 3
chr2_-_209054709 0.13 ENST00000449053.1
ENST00000451346.1
ENST00000341287.4
C2orf80
chromosome 2 open reading frame 80
chr12_+_120875910 0.13 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr15_+_45028753 0.13 ENST00000338264.4
TRIM69
tripartite motif containing 69
chr5_+_145317356 0.13 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr11_+_63993738 0.13 ENST00000441250.2
ENST00000279206.3
NUDT22
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr12_-_120315074 0.13 ENST00000261833.7
ENST00000392521.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr22_+_25003568 0.13 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr13_-_33112899 0.13 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
N4BP2L2
NEDD4 binding protein 2-like 2
chr6_+_31515337 0.13 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr7_-_27169801 0.13 ENST00000511914.1
HOXA4
homeobox A4
chr1_+_149858461 0.13 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr10_-_105677427 0.13 ENST00000369764.1
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chrX_-_21676442 0.13 ENST00000379499.2
KLHL34
kelch-like family member 34
chr4_-_164395014 0.12 ENST00000280605.3
TKTL2
transketolase-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0042369 vitamin D catabolic process(GO:0042369)
0.3 1.3 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.3 1.0 GO:0042704 uterine wall breakdown(GO:0042704)
0.2 0.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 0.9 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.4 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.1 1.5 GO:0007144 female meiosis I(GO:0007144)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 0.3 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.5 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.9 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.6 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.4 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 1.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0006789 bilirubin conjugation(GO:0006789)
0.1 0.2 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 1.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:1905026 regulation of heart looping(GO:1901207) positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.2 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.2 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.6 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.1 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.5 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 1.8 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.0 0.1 GO:0060694 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.1 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.0 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.3 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:2000619 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.0 GO:0043397 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0002251 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.1 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0040008 regulation of growth(GO:0040008)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.0 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.3 1.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 1.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.6 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.2 0.5 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.5 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.6 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0000217 DNA secondary structure binding(GO:0000217)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac