Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for NR1I3

Z-value: 0.38

Motif logo

logo of

Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
NR1I3
ENSG00000143257.7 nuclear receptor subfamily 1 group I member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I3hg19_v2_chr1_-_161208013_161208092,
hg19_v2_chr1_-_161207953_161207975		-0.271.5e-01Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_32407619 2.00 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chrX_-_15619076 0.91 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr12_+_53817633 0.68 ENST00000257863.4
ENST00000550311.1
ENST00000379791.3
AMHR2
anti-Mullerian hormone receptor, type II
chr9_-_75567962 0.67 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr5_+_156712372 0.59 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_-_20126365 0.57 ENST00000294543.6
ENST00000375122.2
TMCO4
transmembrane and coiled-coil domains 4
chr1_+_26036093 0.53 ENST00000374329.1
MAN1C1
mannosidase, alpha, class 1C, member 1
chr6_-_56258892 0.36 ENST00000370819.1
COL21A1
collagen, type XXI, alpha 1
chr17_-_34270668 0.31 ENST00000293274.4
LYZL6
lysozyme-like 6
chr17_-_34270697 0.30 ENST00000585556.1
LYZL6
lysozyme-like 6
chr1_-_23886285 0.30 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr12_-_108991812 0.30 ENST00000392806.3
ENST00000547567.1
TMEM119
transmembrane protein 119
chrX_+_128872998 0.28 ENST00000371106.3
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr6_+_33422343 0.25 ENST00000395064.2
ZBTB9
zinc finger and BTB domain containing 9
chr16_+_30710462 0.25 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr9_+_75766763 0.24 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr7_+_101460882 0.24 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr11_+_63137251 0.23 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr17_+_32582293 0.22 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr1_+_15250596 0.21 ENST00000361144.5
KAZN
kazrin, periplakin interacting protein
chr19_-_49140692 0.17 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr16_+_53133070 0.16 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr20_+_5987890 0.16 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr16_-_16317321 0.16 ENST00000205557.7
ENST00000575728.1
ABCC6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr9_+_124048864 0.15 ENST00000545652.1
GSN
gelsolin
chr11_-_82611448 0.15 ENST00000393399.2
ENST00000313010.3
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr16_+_67906919 0.15 ENST00000358933.5
EDC4
enhancer of mRNA decapping 4
chr1_+_32930647 0.15 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chr20_+_57766075 0.14 ENST00000371030.2
ZNF831
zinc finger protein 831
chr19_-_7562334 0.14 ENST00000593942.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr1_+_145516252 0.14 ENST00000369306.3
PEX11B
peroxisomal biogenesis factor 11 beta
chr16_-_4465886 0.14 ENST00000539968.1
CORO7
coronin 7
chr1_-_151119087 0.14 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr4_+_70894130 0.14 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr1_-_1690014 0.14 ENST00000400922.2
ENST00000342348.5
NADK
NAD kinase
chr1_+_145516560 0.14 ENST00000537888.1
PEX11B
peroxisomal biogenesis factor 11 beta
chr14_+_22977587 0.14 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr9_-_80646374 0.13 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr1_+_160097462 0.13 ENST00000447527.1
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr4_+_37245799 0.13 ENST00000309447.5
KIAA1239
KIAA1239
chr15_+_43885252 0.13 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43985084 0.13 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr1_+_153330322 0.12 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chrX_+_69674943 0.12 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr1_-_205290865 0.11 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr19_-_49140609 0.11 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr15_+_96875657 0.11 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_-_62502639 0.11 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr19_-_6604094 0.10 ENST00000597430.2
CD70
CD70 molecule
chr14_+_22748980 0.10 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr3_-_50396978 0.10 ENST00000266025.3
TMEM115
transmembrane protein 115
chr15_+_96876340 0.09 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_-_8198636 0.09 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr17_-_62502399 0.08 ENST00000450599.2
ENST00000585060.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr5_-_135528822 0.08 ENST00000607574.1
AC009014.3
AC009014.3
chr18_-_19283649 0.08 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr4_-_57524061 0.08 ENST00000508121.1
HOPX
HOP homeobox
chr1_-_32210275 0.08 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr19_-_9968816 0.07 ENST00000590841.1
OLFM2
olfactomedin 2
chr1_-_149900122 0.07 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr10_+_88414338 0.06 ENST00000241891.5
ENST00000443292.1
OPN4
opsin 4
chr3_-_58419537 0.06 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB
pyruvate dehydrogenase (lipoamide) beta
chr11_-_57089671 0.06 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr2_-_86790472 0.06 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr20_+_62339381 0.05 ENST00000355969.6
ENST00000357119.4
ENST00000431125.1
ENST00000369967.3
ENST00000328969.5
ZGPAT
zinc finger, CCCH-type with G patch domain
chr17_-_26694979 0.05 ENST00000438614.1
VTN
vitronectin
chr17_-_26695013 0.05 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr6_+_108487245 0.05 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr13_-_20806440 0.05 ENST00000400066.3
ENST00000400065.3
ENST00000356192.6
GJB6
gap junction protein, beta 6, 30kDa
chr11_+_62556596 0.05 ENST00000526546.1
TMEM179B
transmembrane protein 179B
chr7_-_99381798 0.05 ENST00000415003.1
ENST00000354593.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr11_+_105480740 0.05 ENST00000393125.2
GRIA4
glutamate receptor, ionotropic, AMPA 4
chr8_-_109799793 0.04 ENST00000297459.3
TMEM74
transmembrane protein 74
chr1_-_155159748 0.04 ENST00000473363.2
RP11-201K10.3
RP11-201K10.3
chr16_+_577697 0.04 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15
calpain 15
chr18_-_19284724 0.04 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr2_-_86790593 0.03 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr3_+_122103014 0.03 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
FAM162A
family with sequence similarity 162, member A
chr11_-_104480019 0.03 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr14_+_53173910 0.03 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr14_+_53173890 0.03 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chrX_-_110655391 0.02 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chr8_+_11351876 0.02 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr12_-_75601778 0.02 ENST00000550433.1
ENST00000548513.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr2_-_128642434 0.02 ENST00000393001.1
AMMECR1L
AMMECR1-like
chr20_-_23549334 0.02 ENST00000376979.3
CST9L
cystatin 9-like
chr8_-_53626974 0.02 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr13_+_60971080 0.02 ENST00000377894.2
TDRD3
tudor domain containing 3
chr1_-_27682962 0.01 ENST00000486046.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr9_+_35605274 0.01 ENST00000336395.5
TESK1
testis-specific kinase 1
chr9_-_91793675 0.01 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr6_-_34113856 0.01 ENST00000538487.2
GRM4
glutamate receptor, metabotropic 4
chr16_-_66968055 0.01 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr13_-_114107839 0.01 ENST00000375418.3
ADPRHL1
ADP-ribosylhydrolase like 1
chr12_-_53729525 0.01 ENST00000303846.3
SP7
Sp7 transcription factor
chr19_-_46285646 0.01 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr19_+_12203069 0.00 ENST00000430298.2
ENST00000339302.4
ZNF788
ZNF788
zinc finger family member 788
Zinc finger protein 788
chr5_-_176937351 0.00 ENST00000377112.4
ENST00000501403.2
ENST00000312943.6
DOK3
docking protein 3
chr13_-_95131923 0.00 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr16_-_75018968 0.00 ENST00000262144.6
WDR59
WD repeat domain 59

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.9 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 0.7 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.2 0.7 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.4 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0002254 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.2 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.2 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0030478 actin cap(GO:0030478)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 2.0 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.2 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine