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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR2E1

Z-value: 0.81

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Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
NR2E1
ENSG00000112333.7 nuclear receptor subfamily 2 group E member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2E1hg19_v2_chr6_+_108487245_1084872620.251.8e-01Click!

Activity profile of NR2E1 motif

Sorted Z-values of NR2E1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91539918 2.83 ENST00000548218.1
DCN
decorin
chr2_-_31637560 2.19 ENST00000379416.3
XDH
xanthine dehydrogenase
chr2_+_113885138 1.90 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr5_-_11588907 1.85 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr1_-_205419053 1.83 ENST00000367154.1
LEMD1
LEM domain containing 1
chr4_-_47983519 1.65 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr1_+_32042105 1.58 ENST00000457433.2
ENST00000441210.2
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr11_-_62323702 1.51 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr18_+_29027696 1.48 ENST00000257189.4
DSG3
desmoglein 3
chr4_-_111119804 1.43 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr5_-_11589131 1.42 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr11_-_63439381 1.35 ENST00000538786.1
ENST00000540699.1
ATL3
atlastin GTPase 3
chr12_-_82152444 1.24 ENST00000549325.1
ENST00000550584.2
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr10_+_11784360 1.22 ENST00000379215.4
ENST00000420401.1
ECHDC3
enoyl CoA hydratase domain containing 3
chr17_-_41623691 1.14 ENST00000545954.1
ETV4
ets variant 4
chr12_-_91572278 1.01 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr11_-_63439013 1.00 ENST00000398868.3
ATL3
atlastin GTPase 3
chrX_-_65253506 0.97 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr11_+_35198243 0.97 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr7_+_116166331 0.97 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr6_+_74405501 0.96 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr3_+_121774202 0.95 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr7_+_80267973 0.94 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr12_+_56915776 0.94 ENST00000550726.1
ENST00000542360.1
RBMS2
RNA binding motif, single stranded interacting protein 2
chr7_-_107443652 0.93 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr1_-_162381907 0.90 ENST00000367929.2
ENST00000359567.3
SH2D1B
SH2 domain containing 1B
chr6_+_12290586 0.89 ENST00000379375.5
EDN1
endothelin 1
chr22_-_30695471 0.88 ENST00000434291.1
RP1-130H16.18
Uncharacterized protein
chr17_-_41623716 0.88 ENST00000319349.5
ETV4
ets variant 4
chr11_-_111794446 0.87 ENST00000527950.1
CRYAB
crystallin, alpha B
chr14_+_22977587 0.86 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chrX_+_47444613 0.86 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr16_-_20709066 0.82 ENST00000520010.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr6_-_66417107 0.82 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr2_-_85637459 0.82 ENST00000409921.1
CAPG
capping protein (actin filament), gelsolin-like
chr9_-_21994344 0.80 ENST00000530628.2
ENST00000361570.3
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr7_-_121944491 0.80 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr8_-_16859690 0.80 ENST00000180166.5
FGF20
fibroblast growth factor 20
chrX_-_65259900 0.80 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr12_+_56915713 0.79 ENST00000262031.5
ENST00000552247.2
RBMS2
RNA binding motif, single stranded interacting protein 2
chr2_+_90077680 0.78 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr3_+_136676707 0.78 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr2_-_89442621 0.78 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr17_+_56232494 0.78 ENST00000268912.5
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr4_-_4543700 0.77 ENST00000505286.1
ENST00000306200.2
STX18
syntaxin 18
chr4_+_71063641 0.77 ENST00000514097.1
ODAM
odontogenic, ameloblast asssociated
chrX_+_135614293 0.77 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chrX_-_65259914 0.76 ENST00000374737.4
ENST00000455586.2
VSIG4
V-set and immunoglobulin domain containing 4
chr9_-_110251836 0.76 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr3_-_116163830 0.75 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr11_-_63439174 0.74 ENST00000332645.4
ATL3
atlastin GTPase 3
chr2_+_101437487 0.72 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr2_-_208030647 0.72 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_-_28124903 0.71 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr10_+_124320195 0.71 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr2_-_158300556 0.70 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr14_+_67291158 0.69 ENST00000555456.1
GPHN
gephyrin
chr1_+_25944341 0.68 ENST00000263979.3
MAN1C1
mannosidase, alpha, class 1C, member 1
chr10_+_124320156 0.67 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1
deleted in malignant brain tumors 1
chr6_-_134861089 0.66 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr2_+_135011731 0.66 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr16_-_15180257 0.65 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr17_-_76220740 0.65 ENST00000600484.1
AC087645.1
Uncharacterized protein
chr19_+_11546153 0.64 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr2_+_11679963 0.63 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr12_+_53662073 0.62 ENST00000553219.1
ENST00000257934.4
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr12_+_53662110 0.62 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr9_-_99064386 0.62 ENST00000375262.2
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr17_+_17082842 0.62 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chr19_+_11546093 0.61 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr6_-_112080256 0.61 ENST00000462856.2
ENST00000229471.4
FYN
FYN oncogene related to SRC, FGR, YES
chr1_+_214163033 0.59 ENST00000607425.1
PROX1
prospero homeobox 1
chr12_-_95044309 0.59 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr12_-_52887034 0.58 ENST00000330722.6
KRT6A
keratin 6A
chr3_+_189349162 0.56 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr6_+_106546808 0.56 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr3_+_52812523 0.54 ENST00000540715.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr17_-_40833858 0.53 ENST00000332438.4
CCR10
chemokine (C-C motif) receptor 10
chrX_-_53711064 0.52 ENST00000342160.3
ENST00000446750.1
HUWE1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
chr5_-_179047881 0.52 ENST00000521173.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr19_+_11546440 0.52 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr6_+_125540951 0.49 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr17_-_46667594 0.49 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3
homeobox B3
chr3_+_156799587 0.49 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr6_-_88411911 0.48 ENST00000257787.5
AKIRIN2
akirin 2
chr12_+_14518598 0.48 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
ATF7IP
activating transcription factor 7 interacting protein
chr2_+_192141611 0.47 ENST00000392316.1
MYO1B
myosin IB
chr3_+_141106458 0.47 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr8_+_11666649 0.46 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr17_+_1959369 0.46 ENST00000576444.1
ENST00000322941.3
HIC1
hypermethylated in cancer 1
chr12_-_82152420 0.46 ENST00000552948.1
ENST00000548586.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chrX_-_54824673 0.45 ENST00000218436.6
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr6_+_15246501 0.44 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chrX_-_49041242 0.44 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
PRICKLE3
prickle homolog 3 (Drosophila)
chr11_-_66104237 0.44 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr4_+_96012614 0.44 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chrX_+_47078069 0.44 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
CDK16
cyclin-dependent kinase 16
chr11_-_128457446 0.43 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr1_+_40420802 0.43 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
MFSD2A
major facilitator superfamily domain containing 2A
chr1_+_77333117 0.43 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr4_-_157892055 0.43 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr6_-_130543958 0.43 ENST00000437477.2
ENST00000439090.2
SAMD3
sterile alpha motif domain containing 3
chr10_-_29084886 0.42 ENST00000608061.1
ENST00000443246.2
ENST00000446012.1
LINC00837
long intergenic non-protein coding RNA 837
chr1_+_165864800 0.42 ENST00000469256.2
UCK2
uridine-cytidine kinase 2
chr10_+_52152766 0.42 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr11_-_111781454 0.42 ENST00000533280.1
CRYAB
crystallin, alpha B
chr5_-_140013275 0.41 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr9_+_99691286 0.41 ENST00000372322.3
NUTM2G
NUT family member 2G
chr5_-_127873659 0.41 ENST00000262464.4
FBN2
fibrillin 2
chrX_+_115301975 0.40 ENST00000371906.4
AGTR2
angiotensin II receptor, type 2
chr3_+_42897512 0.40 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr10_-_21786179 0.40 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr10_-_21463116 0.40 ENST00000417816.2
NEBL
nebulette
chr5_-_82969405 0.40 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr2_-_209010874 0.39 ENST00000260988.4
CRYGB
crystallin, gamma B
chr3_+_52813932 0.38 ENST00000537050.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr16_+_3068393 0.38 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr1_-_154155595 0.38 ENST00000328159.4
ENST00000368531.2
ENST00000323144.7
ENST00000368533.3
ENST00000341372.3
TPM3
tropomyosin 3
chr18_+_22040620 0.38 ENST00000426880.2
HRH4
histamine receptor H4
chr17_+_12569306 0.38 ENST00000425538.1
MYOCD
myocardin
chr12_-_10324716 0.37 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr8_-_124408652 0.37 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr1_-_197036364 0.37 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr9_-_97090926 0.37 ENST00000335456.7
ENST00000253262.4
ENST00000341207.4
NUTM2F
NUT family member 2F
chr1_+_154975258 0.36 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr15_+_63188009 0.36 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr1_+_115572415 0.36 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr1_-_20834586 0.36 ENST00000264198.3
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr17_-_46667628 0.35 ENST00000498678.1
HOXB3
homeobox B3
chr14_-_57277163 0.35 ENST00000555006.1
OTX2
orthodenticle homeobox 2
chr17_-_47925379 0.35 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr4_-_52883786 0.35 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr11_-_111781554 0.34 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr12_-_8088871 0.34 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr17_-_73975444 0.34 ENST00000293217.5
ENST00000537812.1
ACOX1
acyl-CoA oxidase 1, palmitoyl
chr1_-_31661000 0.33 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chrX_+_47077632 0.33 ENST00000457458.2
CDK16
cyclin-dependent kinase 16
chr9_-_99064429 0.33 ENST00000375263.3
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr12_-_99548645 0.33 ENST00000549025.2
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr8_+_11561660 0.33 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA4
GATA binding protein 4
chr6_-_9977801 0.33 ENST00000316020.6
ENST00000491508.1
OFCC1
orofacial cleft 1 candidate 1
chr3_-_64673668 0.33 ENST00000498707.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr12_-_91546926 0.33 ENST00000550758.1
DCN
decorin
chr4_-_13546632 0.33 ENST00000382438.5
NKX3-2
NK3 homeobox 2
chrX_-_124097620 0.33 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr19_-_47220335 0.32 ENST00000601806.1
ENST00000593363.1
ENST00000598633.1
ENST00000595515.1
ENST00000433867.1
PRKD2
protein kinase D2
chr18_+_22040593 0.32 ENST00000256906.4
HRH4
histamine receptor H4
chr17_-_41738931 0.32 ENST00000329168.3
ENST00000549132.1
MEOX1
mesenchyme homeobox 1
chr14_+_24407940 0.32 ENST00000354854.1
DHRS4-AS1
DHRS4-AS1
chr1_-_154150651 0.32 ENST00000302206.5
TPM3
tropomyosin 3
chrX_-_33146477 0.32 ENST00000378677.2
DMD
dystrophin
chr19_-_47157914 0.31 ENST00000300875.4
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr7_-_14026063 0.31 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr17_+_35732916 0.31 ENST00000586700.1
C17orf78
chromosome 17 open reading frame 78
chr2_-_106013400 0.31 ENST00000409807.1
FHL2
four and a half LIM domains 2
chr4_-_153303658 0.31 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_-_154155675 0.31 ENST00000330188.9
ENST00000341485.5
TPM3
tropomyosin 3
chr3_-_54962100 0.31 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr13_-_21634421 0.31 ENST00000542899.1
LATS2
large tumor suppressor kinase 2
chr8_+_77593448 0.30 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr20_-_30310797 0.30 ENST00000422920.1
BCL2L1
BCL2-like 1
chr1_+_248201474 0.30 ENST00000366479.2
OR2L2
olfactory receptor, family 2, subfamily L, member 2
chr17_+_35732955 0.30 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr5_+_9546306 0.29 ENST00000508179.1
SNHG18
small nucleolar RNA host gene 18 (non-protein coding)
chr10_-_115423792 0.29 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
NRAP
nebulin-related anchoring protein
chr2_-_183387064 0.29 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_+_161691353 0.28 ENST00000367948.2
FCRLB
Fc receptor-like B
chr5_-_135290705 0.28 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr7_-_1781906 0.28 ENST00000453348.1
ENST00000415399.1
AC074389.9
AC074389.9
chr1_+_225600404 0.28 ENST00000366845.2
AC092811.1
AC092811.1
chr5_-_127873496 0.28 ENST00000508989.1
FBN2
fibrillin 2
chr5_+_32711829 0.28 ENST00000415167.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr17_+_29664830 0.27 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr14_-_57277178 0.27 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr3_+_12392971 0.27 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr8_-_93029520 0.26 ENST00000521553.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_110656005 0.26 ENST00000437679.2
LIMS3
LIM and senescent cell antigen-like domains 3
chr6_+_31515337 0.26 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr1_-_185597619 0.26 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr20_+_62795827 0.26 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr14_+_51955831 0.26 ENST00000356218.4
FRMD6
FERM domain containing 6
chr3_-_33686925 0.25 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr14_+_22636283 0.25 ENST00000557168.1
TRAV30
T cell receptor alpha variable 30
chr17_-_66951474 0.25 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr7_-_16505440 0.25 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr1_-_216596738 0.25 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
USH2A
Usher syndrome 2A (autosomal recessive, mild)
chr1_-_166944561 0.25 ENST00000271417.3
ILDR2
immunoglobulin-like domain containing receptor 2
chr9_-_95244781 0.25 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr6_-_155776966 0.25 ENST00000159060.2
NOX3
NADPH oxidase 3
chr6_+_107077435 0.24 ENST00000369046.4
QRSL1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr2_-_214014959 0.24 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_-_99288536 0.24 ENST00000549797.1
ENST00000333732.7
ENST00000341752.7
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_81187753 0.24 ENST00000312465.7
ENST00000456523.3
FGF5
fibroblast growth factor 5
chr14_+_69865401 0.23 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9
solute carrier family 39, member 9
chr3_-_64673289 0.23 ENST00000295903.4
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr8_-_124037890 0.23 ENST00000519018.1
ENST00000523036.1
DERL1
derlin 1
chr20_+_42574317 0.23 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr16_-_69788816 0.23 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chrX_-_105282712 0.22 ENST00000372563.1
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr7_-_107880508 0.22 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 1.0 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.3 1.0 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 1.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.3 0.9 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 4.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 0.8 GO:0018874 benzoate metabolic process(GO:0018874)
0.3 0.8 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.2 0.7 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 1.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.6 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2 0.8 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.2 0.8 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.2 1.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 1.0 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 1.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.4 GO:0071726 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 0.6 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.1 0.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 1.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.8 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.4 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.1 0.8 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 0.7 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.6 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.3 GO:0003285 septum secundum development(GO:0003285)
0.1 0.3 GO:0061056 sclerotome development(GO:0061056)
0.1 0.8 GO:0021546 rhombomere development(GO:0021546) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.4 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 2.5 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.1 0.8 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.7 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.5 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 1.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 1.0 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.9 GO:0019532 oxalate transport(GO:0019532)
0.1 1.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.1 GO:0070295 renal water absorption(GO:0070295)
0.1 0.3 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.3 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.3 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.5 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.3 GO:0050777 negative regulation of immune response(GO:0050777)
0.1 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.4 GO:0030578 PML body organization(GO:0030578)
0.1 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 3.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 0.4 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 1.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.3 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:0019046 release from viral latency(GO:0019046)
0.0 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.6 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.7 GO:0051775 response to redox state(GO:0051775)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.5 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 2.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 1.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0048690 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.8 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.7 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.6 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 1.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.8 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.5 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0070257 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) positive regulation of mucus secretion(GO:0070257)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.4 GO:0033189 response to vitamin A(GO:0033189)
0.0 1.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 0.8 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.2 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 3.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.7 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.5 GO:0030057 desmosome(GO:0030057)
0.0 1.8 GO:0043034 costamere(GO:0043034)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 2.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0005713 recombination nodule(GO:0005713)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.3 1.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 2.9 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.2 0.7 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.2 1.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 1.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 1.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 0.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.8 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.7 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.7 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.9 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.8 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.7 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 1.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 5.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 2.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.9 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 2.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 5.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.0 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway