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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR2E3

Z-value: 0.47

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Transcription factors associated with NR2E3

Gene Symbol Gene ID Gene Info
NR2E3
ENSG00000031544.10 nuclear receptor subfamily 2 group E member 3

Activity profile of NR2E3 motif

Sorted Z-values of NR2E3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_216257849 1.50 ENST00000456923.1
FN1
fibronectin 1
chrX_-_132887729 1.07 ENST00000406757.2
GPC3
glypican 3
chrX_-_65259914 0.53 ENST00000374737.4
ENST00000455586.2
VSIG4
V-set and immunoglobulin domain containing 4
chr4_+_189060573 0.48 ENST00000332517.3
TRIML1
tripartite motif family-like 1
chr11_+_76745385 0.47 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
B3GNT6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr4_-_110723134 0.45 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr4_-_110723194 0.45 ENST00000394635.3
CFI
complement factor I
chr3_-_195310802 0.45 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chrX_-_65259900 0.44 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr14_+_58754751 0.41 ENST00000598233.1
AL132989.1
AL132989.1
chr4_-_110723335 0.41 ENST00000394634.2
CFI
complement factor I
chr3_-_186262166 0.41 ENST00000307944.5
CRYGS
crystallin, gamma S
chr17_+_12692774 0.40 ENST00000379672.5
ENST00000340825.3
ARHGAP44
Rho GTPase activating protein 44
chr10_-_103603523 0.39 ENST00000370046.1
KCNIP2
Kv channel interacting protein 2
chr4_+_88896819 0.39 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr1_+_47264711 0.39 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1
cytochrome P450, family 4, subfamily B, polypeptide 1
chr9_+_74764278 0.35 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr6_-_4135825 0.33 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
ECI2
enoyl-CoA delta isomerase 2
chr16_-_12184159 0.32 ENST00000312019.2
RP11-276H1.3
RP11-276H1.3
chr8_+_40010989 0.32 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr8_+_66955648 0.32 ENST00000522619.1
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr20_-_56286479 0.32 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr3_-_156534754 0.31 ENST00000472943.1
ENST00000473352.1
LINC00886
long intergenic non-protein coding RNA 886
chr6_-_4135693 0.31 ENST00000495548.1
ENST00000380125.2
ENST00000465828.1
ECI2
enoyl-CoA delta isomerase 2
chr7_-_121944491 0.30 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr8_+_74903580 0.30 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr11_-_10590238 0.29 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr5_+_59783941 0.29 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr11_+_64216546 0.29 ENST00000316124.2
AP003774.4
HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185
chr3_+_160394940 0.29 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr13_-_33780133 0.29 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_-_71182695 0.29 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr17_+_68165657 0.28 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_-_23891658 0.28 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr11_-_10590118 0.27 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr3_-_165555200 0.27 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr6_-_25874440 0.27 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr12_+_20848282 0.26 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr3_+_94657086 0.26 ENST00000463200.1
LINC00879
long intergenic non-protein coding RNA 879
chr19_-_40724246 0.26 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr8_+_103563792 0.26 ENST00000285402.3
ODF1
outer dense fiber of sperm tails 1
chr8_+_77318769 0.25 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr11_-_40315640 0.25 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr19_+_35396219 0.25 ENST00000595783.1
CTC-523E23.6
CTC-523E23.6
chr2_+_149894968 0.24 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chr12_+_20848377 0.24 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr14_+_23654525 0.24 ENST00000399910.1
ENST00000492621.1
C14orf164
chromosome 14 open reading frame 164
chr1_-_112106578 0.24 ENST00000369717.4
ADORA3
adenosine A3 receptor
chr5_+_161274940 0.24 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chrX_-_102565858 0.23 ENST00000449185.1
ENST00000536889.1
BEX2
brain expressed X-linked 2
chr3_+_141105705 0.23 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr3_+_94657118 0.22 ENST00000466089.1
ENST00000470465.1
LINC00879
long intergenic non-protein coding RNA 879
chrX_+_50653784 0.22 ENST00000252677.3
BMP15
bone morphogenetic protein 15
chr20_+_48909240 0.21 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr6_+_21593972 0.21 ENST00000244745.1
ENST00000543472.1
SOX4
SRY (sex determining region Y)-box 4
chr15_+_81591757 0.21 ENST00000558332.1
IL16
interleukin 16
chr1_+_65775204 0.21 ENST00000371069.4
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_+_36641842 0.21 ENST00000523973.1
ENST00000399881.3
KCNU1
potassium channel, subfamily U, member 1
chr15_+_76629064 0.21 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr12_+_20848486 0.21 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr6_+_130339710 0.21 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr6_-_29648887 0.21 ENST00000376883.1
ZFP57
ZFP57 zinc finger protein
chr6_+_54173227 0.20 ENST00000259782.4
ENST00000370864.3
TINAG
tubulointerstitial nephritis antigen
chr7_+_110731062 0.20 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr1_-_146697185 0.20 ENST00000533174.1
ENST00000254090.4
FMO5
flavin containing monooxygenase 5
chr2_+_166095898 0.19 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr17_-_10421853 0.19 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr18_+_3448455 0.19 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr8_+_86121448 0.19 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr16_+_50776021 0.19 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr19_-_14629224 0.19 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_+_12007897 0.18 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr3_+_154958715 0.18 ENST00000462531.1
ENST00000490497.1
RP11-451G4.1
RP11-451G4.1
chr5_-_150473127 0.18 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr16_-_75569068 0.18 ENST00000336257.3
ENST00000565039.1
CHST5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr1_+_149858461 0.18 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr14_+_62462541 0.18 ENST00000430451.2
SYT16
synaptotagmin XVI
chr1_+_153190053 0.18 ENST00000368744.3
PRR9
proline rich 9
chr18_-_70211691 0.17 ENST00000269503.4
CBLN2
cerebellin 2 precursor
chr15_-_58306295 0.17 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr2_-_287320 0.17 ENST00000401503.1
FAM150B
family with sequence similarity 150, member B
chr1_-_17307173 0.17 ENST00000438542.1
ENST00000375535.3
MFAP2
microfibrillar-associated protein 2
chr11_-_41481135 0.17 ENST00000528697.1
ENST00000530763.1
LRRC4C
leucine rich repeat containing 4C
chr2_-_3584430 0.17 ENST00000438482.1
ENST00000422961.1
AC108488.4
AC108488.4
chr3_+_141105235 0.17 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr15_-_65067773 0.16 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr4_+_160188889 0.16 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr13_-_38443860 0.16 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4
transient receptor potential cation channel, subfamily C, member 4
chr11_-_102496063 0.16 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr4_+_96761238 0.16 ENST00000295266.4
PDHA2
pyruvate dehydrogenase (lipoamide) alpha 2
chr4_+_169418255 0.16 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr3_+_148508845 0.16 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr11_-_32452357 0.16 ENST00000379079.2
ENST00000530998.1
WT1
Wilms tumor 1
chr7_-_19813192 0.15 ENST00000422233.1
ENST00000433641.1
TMEM196
transmembrane protein 196
chr8_-_95449155 0.15 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr2_+_190540711 0.15 ENST00000520309.1
ANKAR
ankyrin and armadillo repeat containing
chr22_+_24105394 0.15 ENST00000305199.5
ENST00000382821.3
C22orf15
chromosome 22 open reading frame 15
chr3_+_75955817 0.15 ENST00000487694.3
ENST00000602589.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr3_+_137490748 0.15 ENST00000478772.1
RP11-2A4.3
RP11-2A4.3
chr15_+_54305101 0.15 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C
unc-13 homolog C (C. elegans)
chr17_+_68100989 0.15 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_-_112106556 0.15 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr21_+_43823983 0.15 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr4_+_170581213 0.14 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr1_+_147374915 0.14 ENST00000240986.4
GJA8
gap junction protein, alpha 8, 50kDa
chr5_+_76248538 0.14 ENST00000274368.4
CRHBP
corticotropin releasing hormone binding protein
chr5_-_20575959 0.14 ENST00000507958.1
CDH18
cadherin 18, type 2
chrX_+_54835493 0.14 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr9_+_72658490 0.14 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr9_+_74764340 0.14 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr4_-_76928641 0.14 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr4_-_25865159 0.14 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr14_+_78870030 0.14 ENST00000553631.1
ENST00000554719.1
NRXN3
neurexin 3
chr16_+_30210552 0.14 ENST00000338971.5
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_+_29471210 0.13 ENST00000360423.7
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr6_-_170599561 0.13 ENST00000366756.3
DLL1
delta-like 1 (Drosophila)
chr1_+_200638629 0.13 ENST00000568695.1
RP11-92G12.3
RP11-92G12.3
chr3_+_63428982 0.13 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chr16_+_56995854 0.13 ENST00000566128.1
CETP
cholesteryl ester transfer protein, plasma
chr4_-_2264015 0.13 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr11_-_59952106 0.13 ENST00000529054.1
ENST00000530839.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr7_-_130080818 0.13 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
CEP41
centrosomal protein 41kDa
chr3_+_63428752 0.13 ENST00000295894.5
SYNPR
synaptoporin
chr12_+_41221794 0.13 ENST00000547849.1
CNTN1
contactin 1
chr3_-_21792838 0.13 ENST00000281523.2
ZNF385D
zinc finger protein 385D
chr15_-_99057551 0.13 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr10_-_103603568 0.13 ENST00000356640.2
KCNIP2
Kv channel interacting protein 2
chr3_+_69915385 0.13 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr5_+_140710061 0.13 ENST00000517417.1
ENST00000378105.3
PCDHGA1
protocadherin gamma subfamily A, 1
chr12_-_91539918 0.12 ENST00000548218.1
DCN
decorin
chr19_+_37808778 0.12 ENST00000544914.1
ENST00000589188.1
HKR1
HKR1, GLI-Kruppel zinc finger family member
chrX_-_24665208 0.12 ENST00000356768.4
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr11_-_45307817 0.12 ENST00000020926.3
SYT13
synaptotagmin XIII
chr3_-_33686925 0.12 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr12_+_56661461 0.12 ENST00000546544.1
ENST00000553234.1
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr9_-_140484917 0.12 ENST00000298585.2
ZMYND19
zinc finger, MYND-type containing 19
chr17_-_76870126 0.12 ENST00000586057.1
TIMP2
TIMP metallopeptidase inhibitor 2
chr4_+_110749143 0.12 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr12_+_56661033 0.12 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr19_-_54693521 0.12 ENST00000391754.1
ENST00000245615.1
ENST00000431666.2
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr12_+_51785057 0.12 ENST00000535225.2
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr4_-_153332886 0.12 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr11_+_71640071 0.11 ENST00000533380.1
ENST00000393713.3
ENST00000545854.1
RNF121
ring finger protein 121
chr18_-_72125179 0.11 ENST00000400291.2
FAM69C
family with sequence similarity 69, member C
chr16_+_31404624 0.11 ENST00000389202.2
ITGAD
integrin, alpha D
chr18_+_55816546 0.11 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr16_+_66878282 0.11 ENST00000338437.2
CA7
carbonic anhydrase VII
chr21_+_27543175 0.11 ENST00000608591.1
ENST00000609365.1
AP000230.1
AP000230.1
chr6_-_152639479 0.11 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr6_-_76203345 0.11 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr4_-_76555657 0.11 ENST00000307465.4
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr17_+_36858694 0.11 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr8_-_37457350 0.11 ENST00000519691.1
RP11-150O12.3
RP11-150O12.3
chr5_-_76935513 0.11 ENST00000306422.3
OTP
orthopedia homeobox
chr8_-_15095832 0.11 ENST00000382080.1
SGCZ
sarcoglycan, zeta
chr10_+_31610064 0.11 ENST00000446923.2
ENST00000559476.1
ZEB1
zinc finger E-box binding homeobox 1
chr11_-_108408895 0.11 ENST00000443411.1
ENST00000533052.1
EXPH5
exophilin 5
chr11_+_71640112 0.11 ENST00000530137.1
RNF121
ring finger protein 121
chr6_-_91296737 0.11 ENST00000369332.3
ENST00000369329.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr21_+_27011584 0.11 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
JAM2
junctional adhesion molecule 2
chr13_+_49822041 0.11 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
CDADC1
cytidine and dCMP deaminase domain containing 1
chr19_+_44100632 0.11 ENST00000533118.1
ZNF576
zinc finger protein 576
chr12_+_93963590 0.11 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr5_+_161274685 0.11 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr4_+_159727272 0.10 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr11_-_85338311 0.10 ENST00000376104.2
DLG2
discs, large homolog 2 (Drosophila)
chr17_-_64188177 0.10 ENST00000535342.2
CEP112
centrosomal protein 112kDa
chr19_-_9546177 0.10 ENST00000592292.1
ENST00000588221.1
ZNF266
zinc finger protein 266
chr1_+_107599267 0.10 ENST00000361318.5
ENST00000370078.1
PRMT6
protein arginine methyltransferase 6
chr1_+_84630367 0.10 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_104840093 0.10 ENST00000417440.2
ENST00000444739.2
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr5_+_161275320 0.10 ENST00000437025.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr12_+_32259696 0.10 ENST00000551848.1
BICD1
bicaudal D homolog 1 (Drosophila)
chr4_+_71588372 0.10 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr9_+_91605778 0.10 ENST00000375851.2
ENST00000375850.3
ENST00000334490.5
C9orf47
chromosome 9 open reading frame 47
chr19_+_3762703 0.10 ENST00000589174.1
MRPL54
mitochondrial ribosomal protein L54
chr2_+_33359646 0.10 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr15_-_58571445 0.10 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr2_-_145278475 0.09 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr11_+_111789580 0.09 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr11_+_65266507 0.09 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr12_-_45269430 0.09 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr1_-_85100703 0.09 ENST00000370624.1
C1orf180
chromosome 1 open reading frame 180
chr20_+_42574317 0.09 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr6_+_54172653 0.09 ENST00000370869.3
TINAG
tubulointerstitial nephritis antigen
chr11_-_59951889 0.09 ENST00000532169.1
ENST00000534596.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr20_-_17539456 0.09 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr8_+_106330920 0.09 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr4_-_170948361 0.09 ENST00000393702.3
MFAP3L
microfibrillar-associated protein 3-like
chr4_-_147043058 0.09 ENST00000512063.1
ENST00000507726.1
RP11-6L6.3
long intergenic non-protein coding RNA 1095
chr5_-_147162078 0.09 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr4_-_186317034 0.09 ENST00000505916.1
LRP2BP
LRP2 binding protein
chr10_+_80008505 0.09 ENST00000434974.1
ENST00000423770.1
ENST00000432742.1
LINC00856
long intergenic non-protein coding RNA 856
chr3_+_181429704 0.09 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr3_-_127309879 0.09 ENST00000489960.1
ENST00000490290.1
TPRA1
transmembrane protein, adipocyte asscociated 1
chr22_-_29949680 0.09 ENST00000397873.2
ENST00000490103.1
THOC5
THO complex 5
chr19_-_54693401 0.09 ENST00000338624.6
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr20_-_14318248 0.09 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr11_-_27384737 0.09 ENST00000317945.6
CCDC34
coiled-coil domain containing 34
chr19_-_40596767 0.09 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
ZNF780A
zinc finger protein 780A

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 1.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.4 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.4 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.5 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 0.2 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.2 GO:0060901 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.2 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0072299 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0035799 ureter maturation(GO:0035799)
0.0 0.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.2 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0098736 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0034627 quinolinate biosynthetic process(GO:0019805) 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.1 GO:0061550 cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551)
0.0 0.1 GO:1904596 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0002856 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.0 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.2 0.6 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 0.5 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 0.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.4 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 1.5 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.5 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI