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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR4A1

Z-value: 0.58

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Transcription factors associated with NR4A1

Gene Symbol Gene ID Gene Info
NR4A1
ENSG00000123358.15 nuclear receptor subfamily 4 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A1hg19_v2_chr12_+_52445191_524452430.412.3e-02Click!

Activity profile of NR4A1 motif

Sorted Z-values of NR4A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_63638339 7.18 ENST00000343837.3
ENST00000469440.1
SNTN
sentan, cilia apical structure protein
chr18_-_24722995 2.10 ENST00000581714.1
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr1_+_104293028 2.04 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr20_+_31755934 1.59 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr1_+_212738676 1.34 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr9_-_75567962 1.22 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr1_+_61869748 0.99 ENST00000357977.5
NFIA
nuclear factor I/A
chrX_-_108868390 0.92 ENST00000372101.2
KCNE1L
KCNE1-like
chr16_+_53241854 0.83 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr9_+_1051481 0.82 ENST00000358146.2
ENST00000259622.6
DMRT2
doublesex and mab-3 related transcription factor 2
chr11_+_7618413 0.80 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_+_73109339 0.79 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr3_+_184055240 0.78 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr1_+_16062820 0.77 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr22_+_24891210 0.75 ENST00000382760.2
UPB1
ureidopropionase, beta
chr2_-_25194963 0.75 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr7_-_105516923 0.72 ENST00000478915.1
ATXN7L1
ataxin 7-like 1
chr12_+_109577202 0.72 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr19_+_13134772 0.70 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr6_-_152489484 0.66 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_111743285 0.65 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr4_+_71108300 0.64 ENST00000304954.3
CSN3
casein kappa
chr8_+_99956759 0.64 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr19_+_14138960 0.62 ENST00000431365.2
ENST00000585987.1
RLN3
relaxin 3
chr16_+_691792 0.55 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr2_-_207024233 0.54 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_+_174769006 0.52 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr7_-_105517021 0.52 ENST00000318724.4
ENST00000419735.3
ATXN7L1
ataxin 7-like 1
chr7_+_99933730 0.51 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr19_+_17416457 0.50 ENST00000252602.1
MRPL34
mitochondrial ribosomal protein L34
chr19_+_17416609 0.50 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr6_-_116381918 0.49 ENST00000606080.1
FRK
fyn-related kinase
chr19_+_49713991 0.48 ENST00000597316.1
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr6_+_31895254 0.47 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr20_+_12989596 0.46 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr5_-_169626104 0.45 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1
CTB-27N1.1
chr14_-_35591433 0.44 ENST00000261475.5
ENST00000555644.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr18_-_52969844 0.42 ENST00000561831.3
TCF4
transcription factor 4
chr17_+_73629500 0.40 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr14_-_101295407 0.40 ENST00000596284.1
AL117190.2
AL117190.2
chr2_+_234216454 0.40 ENST00000447536.1
ENST00000409110.1
SAG
S-antigen; retina and pineal gland (arrestin)
chr10_+_104005272 0.40 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr7_-_37488834 0.39 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr11_+_3876859 0.38 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr15_-_42783303 0.38 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr3_+_14989186 0.37 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr3_+_29322437 0.36 ENST00000434693.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr1_+_14075903 0.36 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2
PR domain containing 2, with ZNF domain
chr3_+_101443476 0.34 ENST00000327230.4
ENST00000494050.1
CEP97
centrosomal protein 97kDa
chr20_-_44485835 0.34 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8
acyl-CoA thioesterase 8
chr12_+_32655110 0.33 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr6_+_149068464 0.32 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr8_+_123793633 0.31 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr6_+_31895467 0.30 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr7_-_72936531 0.30 ENST00000339594.4
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr10_-_17171817 0.30 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr1_-_33815486 0.29 ENST00000373418.3
PHC2
polyhomeotic homolog 2 (Drosophila)
chr22_-_51016846 0.28 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr6_+_69942298 0.26 ENST00000238918.8
BAI3
brain-specific angiogenesis inhibitor 3
chr17_-_66287257 0.26 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr22_-_51017084 0.26 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr17_-_7123021 0.25 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr3_+_138340049 0.25 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr2_-_178257401 0.25 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr10_-_61666267 0.25 ENST00000263102.6
CCDC6
coiled-coil domain containing 6
chr20_+_17680587 0.24 ENST00000427254.1
ENST00000377805.3
BANF2
barrier to autointegration factor 2
chr14_-_77495007 0.24 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr2_-_25194476 0.24 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr8_+_99956662 0.23 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr4_-_74088800 0.22 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr12_+_49687425 0.22 ENST00000257860.4
PRPH
peripherin
chr20_+_11898507 0.22 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr5_-_74162605 0.22 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A
family with sequence similarity 169, member A
chr3_-_44519131 0.21 ENST00000425708.2
ENST00000396077.2
ZNF445
zinc finger protein 445
chr1_+_40713573 0.21 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chr3_+_14989076 0.21 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr12_-_16759711 0.21 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_+_64346386 0.20 ENST00000509330.1
PHF3
PHD finger protein 3
chr12_+_54378923 0.20 ENST00000303460.4
HOXC10
homeobox C10
chr6_-_33771757 0.20 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
MLN
motilin
chr6_-_152958521 0.19 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr20_+_17680599 0.19 ENST00000246090.5
BANF2
barrier to autointegration factor 2
chr10_+_101542462 0.19 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr2_-_27603582 0.18 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr22_-_31364187 0.18 ENST00000215862.4
ENST00000397641.3
MORC2
MORC family CW-type zinc finger 2
chr20_+_37590942 0.17 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr14_-_21567009 0.17 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr14_-_21566731 0.17 ENST00000360947.3
ZNF219
zinc finger protein 219
chr11_+_64073699 0.17 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr7_-_6048702 0.15 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr4_-_57253587 0.15 ENST00000513376.1
ENST00000602986.1
ENST00000434343.2
ENST00000451613.1
ENST00000205214.6
ENST00000502617.1
AASDH
aminoadipate-semialdehyde dehydrogenase
chr7_-_6048650 0.14 ENST00000382321.4
ENST00000406569.3
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr3_+_113465866 0.14 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr14_-_95623607 0.13 ENST00000531162.1
ENST00000529720.1
ENST00000343455.3
DICER1
dicer 1, ribonuclease type III
chr19_-_11639931 0.12 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr3_+_51741072 0.12 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2
chr19_-_11639910 0.12 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr2_-_44223138 0.11 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr15_-_41120896 0.10 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr16_+_21312170 0.09 ENST00000338573.5
ENST00000561968.1
CRYM-AS1
CRYM antisense RNA 1
chr7_-_72936608 0.09 ENST00000404251.1
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr8_+_133787586 0.09 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr12_-_95467267 0.09 ENST00000330677.7
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr7_+_119913688 0.08 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr17_-_66287310 0.08 ENST00000582867.1
SLC16A6
solute carrier family 16, member 6
chr17_+_41150479 0.08 ENST00000589913.1
RPL27
ribosomal protein L27
chr4_-_40632605 0.08 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr11_+_278365 0.08 ENST00000534750.1
NLRP6
NLR family, pyrin domain containing 6
chr3_+_184038073 0.08 ENST00000428387.1
ENST00000434061.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr7_-_81399411 0.08 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_+_31895480 0.07 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr13_-_33112823 0.07 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr11_-_111649015 0.07 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr4_-_89744314 0.07 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr7_-_81399329 0.07 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_+_22386325 0.07 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr9_-_139137648 0.07 ENST00000358701.5
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr18_+_43753974 0.07 ENST00000282059.6
ENST00000321319.6
C18orf25
chromosome 18 open reading frame 25
chr17_-_29624343 0.07 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr1_+_173793777 0.06 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr10_+_35484793 0.06 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr1_+_165600436 0.06 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
MGST3
microsomal glutathione S-transferase 3
chr7_+_6048856 0.06 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
AIMP2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr4_-_89744457 0.06 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr15_+_75335604 0.05 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr15_+_36887069 0.05 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr3_+_184037466 0.05 ENST00000441154.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr10_-_74714533 0.05 ENST00000373032.3
PLA2G12B
phospholipase A2, group XIIB
chr17_+_41150793 0.04 ENST00000586277.1
RPL27
ribosomal protein L27
chr19_+_6372444 0.04 ENST00000245812.3
ALKBH7
alkB, alkylation repair homolog 7 (E. coli)
chr17_+_41150290 0.04 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr17_-_2169425 0.02 ENST00000570606.1
ENST00000354901.4
SMG6
SMG6 nonsense mediated mRNA decay factor
chr4_-_89744365 0.02 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr9_+_12693336 0.02 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr1_-_197036364 0.00 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr4_+_100495864 0.00 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr18_-_60986962 0.00 ENST00000333681.4
BCL2
B-cell CLL/lymphoma 2
chr17_+_7123125 0.00 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL
acyl-CoA dehydrogenase, very long chain
chr19_+_4153598 0.00 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 1.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 0.9 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 1.0 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 0.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 0.9 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.8 GO:0061055 myotome development(GO:0061055)
0.1 0.5 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.1 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.1 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.2 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 1.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.0 GO:0072189 ureter development(GO:0072189)
0.0 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.5 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091) regulation of grooming behavior(GO:2000821)
0.0 0.3 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 1.6 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 1.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 0.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.4 GO:0002046 opsin binding(GO:0002046)
0.0 0.3 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 1.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0004530 ribonuclease III activity(GO:0004525) deoxyribonuclease I activity(GO:0004530) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism