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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR4A3

Z-value: 0.78

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Transcription factors associated with NR4A3

Gene Symbol Gene ID Gene Info
NR4A3
ENSG00000119508.13 nuclear receptor subfamily 4 group A member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A3hg19_v2_chr9_+_102584128_1025841440.154.4e-01Click!

Activity profile of NR4A3 motif

Sorted Z-values of NR4A3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_150480576 1.20 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr8_+_99956759 1.18 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr20_+_58179582 1.15 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr8_+_86376081 1.10 ENST00000285379.5
CA2
carbonic anhydrase II
chr19_-_1513188 1.05 ENST00000330475.4
ADAMTSL5
ADAMTS-like 5
chr2_-_31030277 1.01 ENST00000534090.2
ENST00000295055.8
CAPN13
calpain 13
chr9_-_130637244 0.96 ENST00000373156.1
AK1
adenylate kinase 1
chr22_+_31518938 0.95 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chrX_-_43741594 0.92 ENST00000536181.1
ENST00000378069.4
MAOB
monoamine oxidase B
chr7_+_13141097 0.87 ENST00000411542.1
AC011288.2
AC011288.2
chr10_-_105845674 0.85 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr14_+_22984601 0.82 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr2_-_31637560 0.79 ENST00000379416.3
XDH
xanthine dehydrogenase
chr22_+_24891210 0.77 ENST00000382760.2
UPB1
ureidopropionase, beta
chr11_-_66496430 0.74 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr15_+_90728145 0.74 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr4_-_681114 0.74 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr1_+_152957707 0.73 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr7_-_45128472 0.72 ENST00000490531.2
NACAD
NAC alpha domain containing
chr22_-_24384240 0.71 ENST00000439996.2
ENST00000417870.1
GSTT1
glutathione S-transferase theta 1
chr4_+_41614720 0.70 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr8_+_99956662 0.68 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr22_-_24384260 0.68 ENST00000248935.5
GSTT1
glutathione S-transferase theta 1
chr12_+_119616447 0.68 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr4_-_48014931 0.67 ENST00000420489.2
ENST00000504722.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr14_-_107283278 0.67 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chrX_+_44732757 0.66 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A
lysine (K)-specific demethylase 6A
chr12_-_92536433 0.65 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr1_-_17304771 0.60 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr22_+_30792980 0.59 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2
SEC14-like 2 (S. cerevisiae)
chrX_-_15619076 0.58 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr1_-_47655686 0.58 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr1_+_200842083 0.58 ENST00000304244.2
GPR25
G protein-coupled receptor 25
chr19_+_42301079 0.57 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr14_-_81408063 0.57 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr12_-_31158902 0.56 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4
RP11-551L14.4
chr12_-_123215306 0.56 ENST00000356987.2
ENST00000436083.2
HCAR1
hydroxycarboxylic acid receptor 1
chr5_+_218356 0.56 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr11_+_35198243 0.56 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr19_-_4535233 0.55 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr7_-_95025661 0.55 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3
paraoxonase 1
paraoxonase 3
chr15_-_52821020 0.55 ENST00000553916.1
MYO5A
myosin VA (heavy chain 12, myoxin)
chr6_+_19837592 0.55 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr16_+_29823552 0.55 ENST00000300797.6
PRRT2
proline-rich transmembrane protein 2
chr17_+_7211656 0.54 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr19_+_14138960 0.54 ENST00000431365.2
ENST00000585987.1
RLN3
relaxin 3
chr1_+_162351503 0.54 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr5_-_42811986 0.54 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr11_+_66624527 0.53 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr7_-_102158157 0.52 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
RASA4B
RAS p21 protein activator 4B
chr20_+_1875942 0.52 ENST00000358771.4
SIRPA
signal-regulatory protein alpha
chr16_+_29823427 0.52 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
PRRT2
proline-rich transmembrane protein 2
chr11_+_35198118 0.51 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chr9_-_35749162 0.50 ENST00000378094.4
ENST00000378103.3
GBA2
glucosidase, beta (bile acid) 2
chr16_-_58328923 0.50 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54
protease, serine, 54
chr4_+_154622652 0.50 ENST00000260010.6
TLR2
toll-like receptor 2
chr17_-_39928106 0.49 ENST00000540235.1
JUP
junction plakoglobin
chr20_+_61287711 0.48 ENST00000370507.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr9_+_124103625 0.48 ENST00000594963.1
AL161784.1
Uncharacterized protein
chr7_-_74489609 0.46 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
WBSCR16
Williams-Beuren syndrome chromosome region 16
chr10_+_81272287 0.46 ENST00000520547.2
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr11_+_60995849 0.45 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr4_+_41614909 0.44 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr20_-_46415341 0.44 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr20_+_30102231 0.44 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13
histocompatibility (minor) 13
chr20_-_46415297 0.44 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr20_+_1246908 0.44 ENST00000381873.3
ENST00000381867.1
SNPH
syntaphilin
chr19_+_39616410 0.43 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr10_-_79397202 0.43 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr4_-_70080449 0.43 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr4_-_47983519 0.43 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr16_-_58328870 0.43 ENST00000543437.1
PRSS54
protease, serine, 54
chr1_-_144994909 0.43 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_43702231 0.42 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr3_-_58652523 0.42 ENST00000489857.1
ENST00000358781.2
FAM3D
family with sequence similarity 3, member D
chr16_+_2880296 0.42 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr19_-_49339080 0.41 ENST00000595764.1
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr7_-_139763521 0.41 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr8_-_145018905 0.41 ENST00000398774.2
PLEC
plectin
chr2_-_158300556 0.40 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr16_-_20709066 0.40 ENST00000520010.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr4_-_159094194 0.40 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr19_-_45826125 0.40 ENST00000221476.3
CKM
creatine kinase, muscle
chr1_+_92495528 0.39 ENST00000370383.4
EPHX4
epoxide hydrolase 4
chr12_-_7848364 0.39 ENST00000329913.3
GDF3
growth differentiation factor 3
chr18_-_31802282 0.39 ENST00000535475.1
NOL4
nucleolar protein 4
chr5_-_66492562 0.39 ENST00000256447.4
CD180
CD180 molecule
chr20_-_48532019 0.39 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr6_+_36973406 0.39 ENST00000274963.8
FGD2
FYVE, RhoGEF and PH domain containing 2
chr17_-_39274606 0.38 ENST00000391413.2
KRTAP4-11
keratin associated protein 4-11
chr10_-_8095412 0.37 ENST00000458727.1
ENST00000355358.1
RP11-379F12.3
GATA3-AS1
RP11-379F12.3
GATA3 antisense RNA 1
chr22_+_31488433 0.36 ENST00000455608.1
SMTN
smoothelin
chr17_-_2996290 0.36 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr14_-_21492251 0.36 ENST00000554398.1
NDRG2
NDRG family member 2
chr5_-_42812143 0.36 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr22_+_30792846 0.36 ENST00000312932.9
ENST00000428195.1
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr1_-_198990166 0.36 ENST00000427439.1
RP11-16L9.3
RP11-16L9.3
chr19_-_54876558 0.36 ENST00000391742.2
ENST00000434277.2
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr4_-_48136217 0.35 ENST00000264316.4
TXK
TXK tyrosine kinase
chr14_-_21492113 0.34 ENST00000554094.1
NDRG2
NDRG family member 2
chr19_+_11546440 0.34 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr3_-_38691119 0.34 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
chr17_-_41132410 0.34 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr10_-_100206642 0.34 ENST00000361490.4
ENST00000338546.5
ENST00000325103.6
HPS1
Hermansky-Pudlak syndrome 1
chr19_-_7293942 0.34 ENST00000341500.5
ENST00000302850.5
INSR
insulin receptor
chr1_-_113498616 0.34 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr2_+_191792376 0.34 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr19_+_19639670 0.34 ENST00000436027.5
YJEFN3
YjeF N-terminal domain containing 3
chr5_+_179233376 0.33 ENST00000376929.3
ENST00000514093.1
SQSTM1
sequestosome 1
chr18_+_55816546 0.33 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr20_+_36946029 0.33 ENST00000417318.1
BPI
bactericidal/permeability-increasing protein
chr7_-_111202511 0.33 ENST00000452895.1
ENST00000452753.1
ENST00000331762.3
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr14_+_22309368 0.33 ENST00000390433.1
TRAV12-1
T cell receptor alpha variable 12-1
chr7_-_27169801 0.33 ENST00000511914.1
HOXA4
homeobox A4
chr3_-_58613323 0.32 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr19_+_11546153 0.32 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr15_-_78423567 0.32 ENST00000561190.1
ENST00000559645.1
ENST00000560618.1
ENST00000559054.1
CIB2
calcium and integrin binding family member 2
chr19_+_41117770 0.32 ENST00000601032.1
LTBP4
latent transforming growth factor beta binding protein 4
chr19_+_49547099 0.32 ENST00000301408.6
CGB5
chorionic gonadotropin, beta polypeptide 5
chr11_-_117699413 0.31 ENST00000528014.1
FXYD2
FXYD domain containing ion transport regulator 2
chr2_+_37458928 0.30 ENST00000439218.1
ENST00000432075.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr4_-_4543700 0.30 ENST00000505286.1
ENST00000306200.2
STX18
syntaxin 18
chr19_+_42082506 0.30 ENST00000187608.9
ENST00000401445.2
CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
chr4_-_74847800 0.30 ENST00000296029.3
PF4
platelet factor 4
chr1_-_152552980 0.30 ENST00000368787.3
LCE3D
late cornified envelope 3D
chr7_-_20256965 0.30 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr16_-_2827128 0.30 ENST00000494946.2
ENST00000409477.1
ENST00000572954.1
ENST00000262306.7
ENST00000409906.4
TCEB2
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
chr1_-_205325850 0.30 ENST00000537168.1
KLHDC8A
kelch domain containing 8A
chr14_+_77648167 0.30 ENST00000554346.1
ENST00000298351.4
TMEM63C
transmembrane protein 63C
chr11_+_57308979 0.30 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr19_+_49713991 0.30 ENST00000597316.1
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr2_-_75796837 0.29 ENST00000233712.1
EVA1A
eva-1 homolog A (C. elegans)
chr6_-_134861089 0.29 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr19_-_4540486 0.29 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr10_-_50970322 0.29 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr10_-_50970382 0.29 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr14_-_92198403 0.29 ENST00000553329.1
ENST00000256343.3
CATSPERB
catsper channel auxiliary subunit beta
chr17_+_71161140 0.28 ENST00000357585.2
SSTR2
somatostatin receptor 2
chr4_-_25032501 0.28 ENST00000382114.4
LGI2
leucine-rich repeat LGI family, member 2
chr14_-_101295407 0.28 ENST00000596284.1
AL117190.2
AL117190.2
chr4_+_154073469 0.28 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr20_+_19997948 0.28 ENST00000310450.4
ENST00000398602.2
NAA20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr15_-_83621435 0.28 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2
homer homolog 2 (Drosophila)
chr20_-_30458491 0.28 ENST00000339738.5
DUSP15
dual specificity phosphatase 15
chr19_-_54876414 0.28 ENST00000474878.1
ENST00000348231.4
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr14_-_106845789 0.28 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr11_-_110583912 0.28 ENST00000533353.1
ENST00000527598.1
ARHGAP20
Rho GTPase activating protein 20
chr7_-_142120321 0.27 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr17_-_72358001 0.27 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr11_-_61659006 0.27 ENST00000278829.2
FADS3
fatty acid desaturase 3
chr22_+_50354104 0.27 ENST00000360612.4
PIM3
pim-3 oncogene
chr19_+_11546093 0.27 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr14_-_102976135 0.27 ENST00000560748.1
ANKRD9
ankyrin repeat domain 9
chr11_+_67798114 0.27 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr20_-_23860373 0.27 ENST00000304710.4
CST5
cystatin D
chr2_+_37458776 0.27 ENST00000002125.4
ENST00000336237.6
ENST00000431821.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr3_+_196439275 0.27 ENST00000296333.5
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr11_-_117698765 0.27 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr7_-_6048650 0.27 ENST00000382321.4
ENST00000406569.3
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chrX_+_117957741 0.27 ENST00000310164.2
ZCCHC12
zinc finger, CCHC domain containing 12
chr11_-_117698787 0.26 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chr9_-_140095186 0.26 ENST00000409012.4
TPRN
taperin
chr10_-_28571015 0.26 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr7_+_100547156 0.26 ENST00000379458.4
MUC3A
Protein LOC100131514
chr1_+_24645807 0.26 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr3_-_50340996 0.26 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr5_+_149877334 0.26 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr12_+_113376157 0.26 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr8_-_110986918 0.26 ENST00000297404.1
KCNV1
potassium channel, subfamily V, member 1
chr9_+_35749203 0.26 ENST00000456972.2
ENST00000378078.4
RGP1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr12_+_32655048 0.25 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chrX_+_135230712 0.25 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr7_-_6048702 0.25 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr22_-_24110063 0.25 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr12_+_117013656 0.25 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr4_-_40632605 0.25 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr11_+_10472223 0.25 ENST00000396554.3
ENST00000524866.1
AMPD3
adenosine monophosphate deaminase 3
chr19_+_45394477 0.25 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr9_+_34989638 0.25 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr4_+_177241094 0.25 ENST00000503362.1
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr1_+_16083154 0.24 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr7_-_99774945 0.24 ENST00000292377.2
GPC2
glypican 2
chr12_-_120554534 0.24 ENST00000538903.1
ENST00000534951.1
RAB35
RAB35, member RAS oncogene family
chr1_+_24646002 0.24 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr4_-_140527848 0.24 ENST00000608795.1
ENST00000608958.1
SETD7
SET domain containing (lysine methyltransferase) 7
chr19_+_51273721 0.24 ENST00000270590.4
GPR32
G protein-coupled receptor 32
chrX_+_65384182 0.24 ENST00000441993.2
ENST00000419594.1
HEPH
hephaestin
chr16_+_2880254 0.24 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr1_+_24645865 0.24 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr11_+_64073699 0.24 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr1_+_25071848 0.24 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr1_+_184020830 0.24 ENST00000533373.1
ENST00000423085.2
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr19_-_49527590 0.24 ENST00000357383.4
CGB
chorionic gonadotropin, beta polypeptide
chrX_+_47078069 0.23 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
CDK16
cyclin-dependent kinase 16
chrX_+_65384052 0.23 ENST00000336279.5
ENST00000458621.1
HEPH
hephaestin
chr4_-_1723040 0.23 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
TMEM129
transmembrane protein 129
chr2_-_47403642 0.23 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr18_+_55888767 0.23 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr17_-_79995553 0.23 ENST00000581584.1
ENST00000577712.1
ENST00000582900.1
ENST00000579155.1
ENST00000306869.2
DCXR
dicarbonyl/L-xylulose reductase
chr16_+_11038403 0.23 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.4 1.1 GO:0042938 dipeptide transport(GO:0042938)
0.2 0.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.8 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.5 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.6 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) phenylpropanoid catabolic process(GO:0046271)
0.1 1.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 1.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.9 GO:0010044 response to aluminum ion(GO:0010044)
0.1 0.7 GO:0051643 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.1 0.6 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.3 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.6 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.4 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.5 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.1 0.6 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.3 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.1 0.2 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.5 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.3 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.2 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.3 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.5 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.4 GO:0006311 meiotic gene conversion(GO:0006311)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.7 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.3 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.4 GO:0042335 cuticle development(GO:0042335)
0.1 0.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.2 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.1 0.3 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.8 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 1.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.6 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.2 GO:0003164 His-Purkinje system development(GO:0003164)
0.0 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.7 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0035565 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.0 0.4 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.3 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.6 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 1.1 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:0035435 phosphate ion transport(GO:0006817) phosphate ion transmembrane transport(GO:0035435)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.1 GO:0060459 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) superior vena cava morphogenesis(GO:0060578)
0.0 0.3 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.8 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0045963 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.0 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.0 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.1 GO:0002554 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0060405 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1904978 regulation of endosome organization(GO:1904978)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.1 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.0 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.0 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.6 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.9 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.1 GO:0060389 pathway-restricted SMAD protein phosphorylation(GO:0060389) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0 0.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.0 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:1903593 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 0.6 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 1.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.3 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1 1.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.5 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.7 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.6 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.0 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0008431 vitamin E binding(GO:0008431)
0.2 0.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 0.6 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.2 1.6 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.3 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.3 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.1 0.5 GO:0004348 glucosylceramidase activity(GO:0004348) beta-glucosidase activity(GO:0008422)
0.1 0.9 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.8 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.0 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 0.4 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 1.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0017153 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.3 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.0 GO:0031877 somatostatin receptor binding(GO:0031877)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.1 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism