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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR5A2

Z-value: 1.37

Motif logo

Transcription factors associated with NR5A2

Gene Symbol Gene ID Gene Info
ENSG00000116833.9 nuclear receptor subfamily 5 group A member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR5A2hg19_v2_chr1_+_199996702_199996732-0.115.8e-01Click!

Activity profile of NR5A2 motif

Sorted Z-values of NR5A2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_58152524 4.85 ENST00000359926.3
phosphatase and actin regulator 3
chr10_+_118187379 3.58 ENST00000369230.3
pancreatic lipase-related protein 3
chr20_+_58179582 3.25 ENST00000371015.1
ENST00000395639.4
phosphatase and actin regulator 3
chr3_-_122102065 2.32 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
coiled-coil domain containing 58
chr5_-_54281407 2.26 ENST00000381403.4
endothelial cell-specific molecule 1
chr1_-_146696901 2.03 ENST00000369272.3
ENST00000441068.2
flavin containing monooxygenase 5
chr8_-_110704014 1.94 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
syntabulin (syntaxin-interacting)
chr22_+_31518938 1.80 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
inositol polyphosphate-5-phosphatase J
chr9_-_130637244 1.75 ENST00000373156.1
adenylate kinase 1
chr1_-_146697185 1.72 ENST00000533174.1
ENST00000254090.4
flavin containing monooxygenase 5
chr5_-_134914673 1.72 ENST00000512158.1
chemokine (C-X-C motif) ligand 14
chr20_+_42086525 1.67 ENST00000244020.3
serine/arginine-rich splicing factor 6
chr1_+_152881014 1.65 ENST00000368764.3
ENST00000392667.2
involucrin
chr2_+_135011731 1.59 ENST00000281923.2
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr10_+_81107271 1.47 ENST00000448165.1
peptidylprolyl isomerase F
chr4_-_74864386 1.46 ENST00000296027.4
chemokine (C-X-C motif) ligand 5
chr3_-_58652523 1.43 ENST00000489857.1
ENST00000358781.2
family with sequence similarity 3, member D
chr10_+_102891048 1.43 ENST00000467928.2
T-cell leukemia homeobox 1
chr6_-_97345689 1.39 ENST00000316149.7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr14_-_21491477 1.37 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG family member 2
chr21_+_41029235 1.31 ENST00000380618.1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr14_-_106054659 1.26 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr14_-_21492251 1.25 ENST00000554398.1
NDRG family member 2
chr14_-_21492113 1.23 ENST00000554094.1
NDRG family member 2
chr17_+_46970134 1.20 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr17_+_46970178 1.20 ENST00000393366.2
ENST00000506855.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr17_-_56084578 1.17 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
serine/arginine-rich splicing factor 1
chr2_-_238499303 1.16 ENST00000409576.1
RAB17, member RAS oncogene family
chr1_-_149858227 1.16 ENST00000369155.2
histone cluster 2, H2be
chr7_-_95225768 1.16 ENST00000005178.5
pyruvate dehydrogenase kinase, isozyme 4
chr11_+_126139005 1.16 ENST00000263578.5
ENST00000442061.2
ENST00000532125.1
FAD-dependent oxidoreductase domain containing 1
chr22_-_24110063 1.13 ENST00000520222.1
ENST00000401675.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chr17_+_46970127 1.13 ENST00000355938.5
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr8_+_144295067 1.11 ENST00000330824.2
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr19_+_15052301 1.08 ENST00000248072.3
olfactory receptor, family 7, subfamily C, member 2
chr7_-_25164868 1.07 ENST00000409409.1
ENST00000409764.1
ENST00000413447.1
cytochrome c, somatic
chr7_+_89841000 1.06 ENST00000287908.3
STEAP family member 2, metalloreductase
chr4_-_681114 1.06 ENST00000503156.1
major facilitator superfamily domain containing 7
chr9_-_130639997 1.06 ENST00000373176.1
adenylate kinase 1
chr11_+_66059339 1.04 ENST00000327259.4
transmembrane protein 151A
chr7_+_89841024 1.03 ENST00000394626.1
STEAP family member 2, metalloreductase
chr7_-_99569468 1.03 ENST00000419575.1
alpha-2-glycoprotein 1, zinc-binding
chr1_+_161195781 1.01 ENST00000367988.3
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr4_-_170947522 1.00 ENST00000361618.3
microfibrillar-associated protein 3-like
chr2_+_120189422 0.99 ENST00000306406.4
transmembrane protein 37
chr1_-_207119738 0.98 ENST00000356495.4
polymeric immunoglobulin receptor
chr3_+_133465228 0.96 ENST00000482271.1
ENST00000264998.3
transferrin
chr14_-_24806588 0.96 ENST00000555591.1
ENST00000554569.1
Uncharacterized protein
receptor-interacting serine-threonine kinase 3
chr16_-_20709066 0.93 ENST00000520010.1
acyl-CoA synthetase medium-chain family member 1
chr5_+_175085033 0.92 ENST00000377291.2
histamine receptor H2
chr19_+_17416609 0.92 ENST00000602206.1
mitochondrial ribosomal protein L34
chr8_-_110703819 0.91 ENST00000532779.1
ENST00000534578.1
syntabulin (syntaxin-interacting)
chr14_-_23624511 0.91 ENST00000529705.2
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr5_+_218356 0.90 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr21_+_42694732 0.89 ENST00000398646.3
family with sequence similarity 3, member B
chr3_+_51705222 0.89 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
testis expressed 264
chr19_+_17416457 0.89 ENST00000252602.1
mitochondrial ribosomal protein L34
chr11_-_34937858 0.87 ENST00000278359.5
APAF1 interacting protein
chr19_-_4535233 0.87 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
perilipin 5
chr17_-_9683238 0.87 ENST00000571771.1
dehydrogenase/reductase (SDR family) member 7C
chr11_+_57480046 0.87 ENST00000378312.4
ENST00000278422.4
thioredoxin-related transmembrane protein 2
chr19_+_46850320 0.87 ENST00000391919.1
protein phosphatase 5, catalytic subunit
chr3_+_186358148 0.85 ENST00000382134.3
ENST00000265029.3
fetuin B
chr1_+_29138654 0.83 ENST00000234961.2
opioid receptor, delta 1
chr19_+_46850251 0.82 ENST00000012443.4
protein phosphatase 5, catalytic subunit
chr3_+_186358200 0.82 ENST00000382136.3
fetuin B
chr18_-_12377283 0.82 ENST00000269143.3
AFG3-like AAA ATPase 2
chr2_-_238499725 0.81 ENST00000264601.3
RAB17, member RAS oncogene family
chr2_-_7005785 0.81 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr22_+_39348723 0.80 ENST00000402255.1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr19_-_7293942 0.80 ENST00000341500.5
ENST00000302850.5
insulin receptor
chr17_+_900342 0.80 ENST00000327158.4
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr1_-_203155868 0.79 ENST00000255409.3
chitinase 3-like 1 (cartilage glycoprotein-39)
chr2_-_238499131 0.78 ENST00000538644.1
RAB17, member RAS oncogene family
chr9_-_130679257 0.78 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr16_-_58328870 0.78 ENST00000543437.1
protease, serine, 54
chr1_+_26146397 0.77 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
mitochondrial fission regulator 1-like
chr16_-_58328923 0.77 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
protease, serine, 54
chr22_-_42486747 0.76 ENST00000602404.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chr1_+_207226574 0.75 ENST00000367080.3
ENST00000367079.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr13_+_47127322 0.74 ENST00000389798.3
leucine-rich repeats and calponin homology (CH) domain containing 1
chr6_+_107349392 0.74 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
chromosome 6 open reading frame 203
chr11_+_66624527 0.73 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr17_-_72855989 0.73 ENST00000293190.5
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr3_-_38691119 0.72 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
sodium channel, voltage-gated, type V, alpha subunit
chr17_-_39928106 0.72 ENST00000540235.1
junction plakoglobin
chr10_-_50970382 0.71 ENST00000419399.1
ENST00000432695.1
oxoglutarate dehydrogenase-like
chr1_+_26147319 0.71 ENST00000374300.3
mitochondrial fission regulator 1-like
chr16_-_12897642 0.71 ENST00000433677.2
ENST00000261660.4
ENST00000381774.4
calcineurin-like phosphoesterase domain containing 1
chr10_-_50970322 0.70 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr14_-_106174960 0.70 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr3_-_58613323 0.69 ENST00000474531.1
ENST00000465970.1
family with sequence similarity 107, member A
chr1_+_228337553 0.69 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr14_+_93897272 0.69 ENST00000393151.2
unc-79 homolog (C. elegans)
chr17_+_7211656 0.68 ENST00000416016.2
eukaryotic translation initiation factor 5A
chr20_+_37434329 0.67 ENST00000299824.1
ENST00000373331.2
protein phosphatase 1, regulatory subunit 16B
chr1_+_44584522 0.67 ENST00000372299.3
Kruppel-like factor 17
chr10_+_105156364 0.67 ENST00000369797.3
programmed cell death 11
chr15_+_78441663 0.66 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
isocitrate dehydrogenase 3 (NAD+) alpha
chr1_-_1711508 0.65 ENST00000378625.1
NAD kinase
chr1_-_20126365 0.65 ENST00000294543.6
ENST00000375122.2
transmembrane and coiled-coil domains 4
chr14_+_93897199 0.64 ENST00000553484.1
unc-79 homolog (C. elegans)
chr3_-_183735651 0.64 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr16_-_4588469 0.63 ENST00000588381.1
ENST00000563332.2
cell death-inducing p53 target 1
chr3_+_113666748 0.63 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chr9_+_33240157 0.62 ENST00000379721.3
serine peptidase inhibitor, Kazal type 4
chr7_+_37960163 0.62 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
ependymin related 1
chrX_+_153455547 0.61 ENST00000430054.1
opsin 1 (cone pigments), medium-wave-sensitive
chr1_-_27240455 0.61 ENST00000254227.3
nuclear receptor subfamily 0, group B, member 2
chr7_-_25164969 0.60 ENST00000305786.2
cytochrome c, somatic
chr19_+_42212526 0.59 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr16_-_20681177 0.59 ENST00000524149.1
acyl-CoA synthetase medium-chain family member 1
chr4_-_69111401 0.59 ENST00000332644.5
transmembrane protease, serine 11B
chr20_-_48532019 0.59 ENST00000289431.5
spermatogenesis associated 2
chr1_-_144995074 0.58 ENST00000534536.1
phosphodiesterase 4D interacting protein
chr3_-_195808952 0.58 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
transferrin receptor
chr6_+_32006159 0.57 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr4_+_41614720 0.57 ENST00000509277.1
LIM and calponin homology domains 1
chr6_+_32006042 0.56 ENST00000418967.2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr16_-_67224002 0.56 ENST00000563889.1
ENST00000564418.1
ENST00000545725.2
ENST00000314586.6
exocyst complex component 3-like 1
chr1_+_26146674 0.56 ENST00000525713.1
ENST00000374301.3
mitochondrial fission regulator 1-like
chr2_-_220119280 0.55 ENST00000392088.2
tubulin, alpha 4a
chr5_-_148033726 0.55 ENST00000354217.2
ENST00000314512.6
ENST00000362016.2
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr3_+_9745510 0.55 ENST00000383831.3
copine family member IX
chr19_-_40931891 0.55 ENST00000357949.4
SERTA domain containing 1
chr1_+_16348525 0.55 ENST00000331433.4
chloride channel, voltage-sensitive Ka
chr9_-_140095186 0.54 ENST00000409012.4
taperin
chr11_+_63304273 0.54 ENST00000439013.2
ENST00000255688.3
retinoic acid receptor responder (tazarotene induced) 3
chr17_+_40985407 0.54 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr20_+_49126881 0.53 ENST00000371621.3
ENST00000541713.1
protein tyrosine phosphatase, non-receptor type 1
chr11_-_110583912 0.53 ENST00000533353.1
ENST00000527598.1
Rho GTPase activating protein 20
chr10_-_120925054 0.53 ENST00000419372.1
ENST00000369131.4
ENST00000330036.6
ENST00000355697.2
sideroflexin 4
chr3_-_187454281 0.53 ENST00000232014.4
B-cell CLL/lymphoma 6
chr14_-_21491305 0.53 ENST00000554531.1
NDRG family member 2
chr11_+_10472223 0.53 ENST00000396554.3
ENST00000524866.1
adenosine monophosphate deaminase 3
chr5_+_140430979 0.53 ENST00000306549.3
protocadherin beta 1
chr17_-_3417062 0.52 ENST00000570318.1
ENST00000541913.1
spermatogenesis associated 22
chr14_-_96180435 0.52 ENST00000556450.1
ENST00000555202.1
ENST00000554012.1
ENST00000402399.1
T-cell leukemia/lymphoma 1A
chr11_-_111781554 0.52 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr1_-_40105617 0.52 ENST00000372852.3
hes-related family bHLH transcription factor with YRPW motif-like
chr22_+_23412479 0.52 ENST00000248996.4
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr4_-_170947485 0.52 ENST00000504999.1
microfibrillar-associated protein 3-like
chr10_+_82300575 0.51 ENST00000313455.4
SH2 domain containing 4B
chr3_-_195808980 0.51 ENST00000360110.4
transferrin receptor
chr6_-_52860171 0.51 ENST00000370963.4
glutathione S-transferase alpha 4
chr1_-_110284384 0.51 ENST00000540225.1
glutathione S-transferase mu 3 (brain)
chr5_-_131879205 0.50 ENST00000231454.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr12_-_56652111 0.50 ENST00000267116.7
ankyrin repeat domain 52
chr1_+_16348366 0.50 ENST00000375692.1
ENST00000420078.1
chloride channel, voltage-sensitive Ka
chr20_-_36889127 0.50 ENST00000279024.4
KIAA1755
chr17_-_46035187 0.50 ENST00000300557.2
proline rich 15-like
chr11_-_34938039 0.50 ENST00000395787.3
APAF1 interacting protein
chr13_+_114321463 0.50 ENST00000335678.6
G protein-coupled receptor kinase 1
chr7_-_38389573 0.50 ENST00000390344.2
T cell receptor gamma variable 5
chr4_-_170947565 0.50 ENST00000506764.1
microfibrillar-associated protein 3-like
chr20_+_1875942 0.50 ENST00000358771.4
signal-regulatory protein alpha
chr15_+_45422131 0.49 ENST00000321429.4
dual oxidase 1
chr14_-_21490958 0.49 ENST00000554104.1
NDRG family member 2
chr15_-_83621435 0.49 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
homer homolog 2 (Drosophila)
chr19_+_55851221 0.49 ENST00000255613.3
ENST00000539076.1
suppressor of variegation 4-20 homolog 2 (Drosophila)
Uncharacterized protein
chr8_+_145149930 0.49 ENST00000318911.4
cytochrome c-1
chr2_-_74374995 0.49 ENST00000295326.4
bolA family member 3
chr5_-_41213607 0.49 ENST00000337836.5
ENST00000433294.1
complement component 6
chr22_-_39636914 0.49 ENST00000381551.4
platelet-derived growth factor beta polypeptide
chr1_-_31661000 0.49 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
Na+/K+ transporting ATPase interacting 1
chr7_+_100318423 0.48 ENST00000252723.2
erythropoietin
chr10_-_101190202 0.48 ENST00000543866.1
ENST00000370508.5
glutamic-oxaloacetic transaminase 1, soluble
chr15_+_45422178 0.48 ENST00000389037.3
ENST00000558322.1
dual oxidase 1
chr22_-_39637135 0.48 ENST00000440375.1
platelet-derived growth factor beta polypeptide
chr1_+_116519112 0.48 ENST00000369503.4
solute carrier family 22, member 15
chr8_+_125551338 0.47 ENST00000276689.3
ENST00000518008.1
ENST00000522532.1
ENST00000517367.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr2_+_24714729 0.47 ENST00000406961.1
ENST00000405141.1
nuclear receptor coactivator 1
chr1_+_1260147 0.47 ENST00000343938.4
glycolipid transfer protein domain containing 1
chr3_-_49941042 0.47 ENST00000344206.4
ENST00000296474.3
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr15_-_81616446 0.47 ENST00000302824.6
StAR-related lipid transfer (START) domain containing 5
chr17_+_48423453 0.46 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
xylosyltransferase II
chr12_+_32832203 0.46 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
dynamin 1-like
chr17_+_79670386 0.46 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr6_+_43484760 0.46 ENST00000372389.3
ENST00000372344.2
ENST00000304004.3
ENST00000423780.1
polymerase (RNA) I polypeptide C, 30kDa
chr5_+_150639360 0.46 ENST00000523004.1
GM2 ganglioside activator
chr2_-_31361543 0.46 ENST00000349752.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr1_+_104068312 0.46 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNA-binding region (RNP1, RRM) containing 3
chr17_+_48585794 0.45 ENST00000576179.1
ENST00000419930.1
MYCBP associated protein
chr16_+_57481349 0.45 ENST00000262507.6
ENST00000565964.1
coenzyme Q9
chr11_+_77899920 0.45 ENST00000528910.1
ENST00000529308.1
ubiquitin specific peptidase 35
chr4_-_74904398 0.45 ENST00000296026.4
chemokine (C-X-C motif) ligand 3
chr8_+_55047763 0.45 ENST00000260102.4
ENST00000519831.1
mitochondrial ribosomal protein L15
chr7_+_44646162 0.44 ENST00000439616.2
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr4_+_74735102 0.44 ENST00000395761.3
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr19_-_4517613 0.44 ENST00000301286.3
perilipin 4
chr15_+_89346657 0.44 ENST00000439576.2
aggrecan
chr19_-_39826639 0.44 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chr12_+_50505963 0.44 ENST00000550654.1
ENST00000548985.1
cytochrome c oxidase assembly homolog 14 (S. cerevisiae)
chr2_+_198365095 0.44 ENST00000409468.1
heat shock 10kDa protein 1
chr1_+_16348497 0.44 ENST00000439316.2
chloride channel, voltage-sensitive Ka
chr8_+_9009202 0.44 ENST00000518496.1
Uncharacterized protein
chr4_-_170948361 0.44 ENST00000393702.3
microfibrillar-associated protein 3-like
chr19_-_51336443 0.44 ENST00000598673.1
kallikrein-related peptidase 15
chr19_-_55574538 0.43 ENST00000415061.3
retinol dehydrogenase 13 (all-trans/9-cis)
chr19_-_1513188 0.43 ENST00000330475.4
ADAMTS-like 5

Network of associatons between targets according to the STRING database.

First level regulatory network of NR5A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.5 1.6 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5 1.5 GO:0018874 benzoate metabolic process(GO:0018874)
0.5 1.5 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.4 0.9 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4 1.2 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.4 2.8 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3 1.0 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.3 4.9 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.3 1.7 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.3 2.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 0.8 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.3 2.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 1.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.3 0.8 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 1.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2 1.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 1.0 GO:1905174 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 1.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.2 0.7 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2 0.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.8 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2 2.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 0.8 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 1.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 1.0 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 0.7 GO:0006218 uridine catabolic process(GO:0006218)
0.2 1.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 1.8 GO:0070269 pyroptosis(GO:0070269)
0.2 0.5 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.2 0.5 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 0.5 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2 1.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.2 1.0 GO:0042335 cuticle development(GO:0042335)
0.2 1.0 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2 0.5 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 0.5 GO:0090149 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.2 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.1 4.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.1 0.4 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.8 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.5 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 1.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.4 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.5 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.6 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 2.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.3 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.4 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.6 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.2 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.8 GO:0061589 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.1 0.3 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.5 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 0.5 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.1 0.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.1 0.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 2.2 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.1 GO:0097286 iron ion import(GO:0097286)
0.1 1.4 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.3 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 0.5 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 1.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 1.2 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 1.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 6.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.7 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 2.2 GO:0009060 aerobic respiration(GO:0009060)
0.1 1.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.7 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.5 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.3 GO:0060356 leucine import(GO:0060356)
0.1 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.4 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 2.9 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 0.3 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628) somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.3 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.9 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.7 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.3 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 1.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.3 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.2 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647) negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.7 GO:0051601 exocyst localization(GO:0051601)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.4 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.2 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 1.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.4 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0061341 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) hypophysis morphogenesis(GO:0048850) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) negative regulation of secondary metabolite biosynthetic process(GO:1900377) inhibitory synapse assembly(GO:1904862) regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.2 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.7 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 2.6 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 3.9 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.7 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 1.2 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 1.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) response to cortisol(GO:0051414) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.7 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.5 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0006014 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.4 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:1903588 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 1.0 GO:0071806 protein transmembrane transport(GO:0071806)
0.0 0.1 GO:0033563 spinal cord ventral commissure morphogenesis(GO:0021965) dorsal/ventral axon guidance(GO:0033563)
0.0 0.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.4 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.6 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) regulation of late endosome to lysosome transport(GO:1902822) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:0035565 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.2 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.0 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.9 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.1 GO:0042407 cristae formation(GO:0042407)
0.0 1.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.3 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.2 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.4 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.0 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.4 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0 0.3 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.4 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.2 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.3 1.4 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 1.7 GO:1990635 proximal dendrite(GO:1990635)
0.2 2.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 2.9 GO:0097433 dense body(GO:0097433)
0.2 3.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 0.8 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.1 2.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 2.0 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.9 GO:0005915 zonula adherens(GO:0005915)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.4 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.6 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.4 GO:0070470 plasma membrane respiratory chain(GO:0070470)
0.1 0.2 GO:0031523 Myb complex(GO:0031523)
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.4 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 1.2 GO:0097227 sperm annulus(GO:0097227)
0.1 0.3 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.1 0.5 GO:0097443 sorting endosome(GO:0097443)
0.1 4.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 4.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0061617 MICOS complex(GO:0061617)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.3 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 2.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.6 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.9 GO:0097342 ripoptosome(GO:0097342)
0.0 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 7.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.6 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 1.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 6.2 GO:0030426 growth cone(GO:0030426)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 1.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 5.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 1.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.7 2.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.7 2.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.5 1.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.4 1.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.4 3.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 2.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 2.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 2.0 GO:0035473 lipase binding(GO:0035473)
0.3 1.6 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 0.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 8.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.8 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 1.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 3.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.9 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.2 0.6 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 2.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.5 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.2 0.5 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 3.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 0.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 0.8 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.2 0.2 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2 0.5 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.7 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 3.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.4 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.6 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.8 GO:0043559 insulin binding(GO:0043559) PTB domain binding(GO:0051425)
0.1 0.4 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 1.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 1.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.7 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.5 GO:0051540 iron-sulfur cluster binding(GO:0051536) 2 iron, 2 sulfur cluster binding(GO:0051537) metal cluster binding(GO:0051540)
0.1 2.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.2 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.7 GO:0004985 opioid receptor activity(GO:0004985)
0.1 2.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0008443 phosphofructokinase activity(GO:0008443)
0.1 1.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 1.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.7 GO:0004568 chitinase activity(GO:0004568)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 3.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 3.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.6 GO:0032052 bile acid binding(GO:0032052)
0.0 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 1.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 0.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 3.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 2.9 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 4.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 3.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 6.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 1.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 2.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 2.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.8 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.7 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus