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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR6A1

Z-value: 0.69

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Transcription factors associated with NR6A1

Gene Symbol Gene ID Gene Info
NR6A1
ENSG00000148200.12 nuclear receptor subfamily 6 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR6A1hg19_v2_chr9_-_127533519_1275335760.412.6e-02Click!

Activity profile of NR6A1 motif

Sorted Z-values of NR6A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_41620335 4.42 ENST00000331105.2
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr4_-_7044657 4.10 ENST00000310085.4
CCDC96
coiled-coil domain containing 96
chr5_+_94727048 3.45 ENST00000283357.5
FAM81B
family with sequence similarity 81, member B
chr21_+_42694732 3.07 ENST00000398646.3
FAM3B
family with sequence similarity 3, member B
chr16_+_777118 2.59 ENST00000562141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chrY_-_21906623 2.27 ENST00000382806.2
KDM5D
lysine (K)-specific demethylase 5D
chr17_+_4981535 2.18 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr10_-_61513146 2.16 ENST00000430431.1
LINC00948
long intergenic non-protein coding RNA 948
chr14_-_106642049 1.97 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr7_+_23719749 1.93 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A
family with sequence similarity 221, member A
chr11_+_111789580 1.77 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr10_-_61513201 1.70 ENST00000414264.1
ENST00000594536.1
LINC00948
long intergenic non-protein coding RNA 948
chr20_+_31749574 1.60 ENST00000253362.2
BPIFA2
BPI fold containing family A, member 2
chr5_-_41213607 1.59 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr11_-_108464465 1.56 ENST00000525344.1
EXPH5
exophilin 5
chr4_+_39184024 1.55 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19
WD repeat domain 19
chr22_-_30867973 1.53 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr2_-_60780607 1.49 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr11_-_108464321 1.38 ENST00000265843.4
EXPH5
exophilin 5
chr19_-_9006766 1.38 ENST00000599436.1
MUC16
mucin 16, cell surface associated
chr16_+_777246 1.34 ENST00000561546.1
ENST00000564545.1
ENST00000389703.3
ENST00000567414.1
ENST00000568141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr2_-_220108309 1.30 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chr9_+_74764340 1.24 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr12_+_102091400 1.22 ENST00000229266.3
ENST00000549872.1
CHPT1
choline phosphotransferase 1
chr2_+_54558004 1.21 ENST00000405749.1
ENST00000398634.2
ENST00000447328.1
C2orf73
chromosome 2 open reading frame 73
chr16_+_77756399 1.17 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr1_+_225997791 1.14 ENST00000445856.1
ENST00000272167.5
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr19_-_9003586 1.13 ENST00000380951.5
MUC16
mucin 16, cell surface associated
chr6_+_84743436 1.13 ENST00000257776.4
MRAP2
melanocortin 2 receptor accessory protein 2
chr6_-_43197189 1.12 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr1_-_109203648 1.11 ENST00000370031.1
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr11_-_5271122 1.10 ENST00000330597.3
HBG1
hemoglobin, gamma A
chr16_+_30212378 1.10 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr11_+_113185251 1.09 ENST00000529221.1
TTC12
tetratricopeptide repeat domain 12
chr7_-_95225768 1.07 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr19_-_6720686 1.07 ENST00000245907.6
C3
complement component 3
chr21_-_46330545 1.03 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chrY_+_16636354 1.01 ENST00000339174.5
NLGN4Y
neuroligin 4, Y-linked
chr2_+_69240302 0.97 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr16_+_776936 0.96 ENST00000549114.1
ENST00000341413.4
ENST00000562187.1
ENST00000564537.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr8_+_144640477 0.94 ENST00000262580.4
GSDMD
gasdermin D
chr7_-_150038704 0.94 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr3_-_148804275 0.94 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF
helicase-like transcription factor
chr3_+_108321623 0.93 ENST00000497905.1
ENST00000463306.1
DZIP3
DAZ interacting zinc finger protein 3
chr7_+_94536898 0.92 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr16_-_21170762 0.91 ENST00000261383.3
ENST00000415178.1
DNAH3
dynein, axonemal, heavy chain 3
chr8_-_27472198 0.90 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU
clusterin
chr8_-_72268968 0.87 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr12_+_9980113 0.86 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr1_+_156338993 0.84 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr5_+_134240800 0.82 ENST00000512783.1
PCBD2
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr1_+_212738676 0.82 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr19_+_11455900 0.82 ENST00000588790.1
CCDC159
coiled-coil domain containing 159
chr10_+_695888 0.81 ENST00000441152.2
PRR26
proline rich 26
chr8_-_72268889 0.81 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chrX_-_46187069 0.80 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr13_-_24463530 0.79 ENST00000382172.3
MIPEP
mitochondrial intermediate peptidase
chr10_+_16478942 0.77 ENST00000535784.2
ENST00000423462.2
ENST00000378000.1
PTER
phosphotriesterase related
chr6_+_43028182 0.76 ENST00000394058.1
KLC4
kinesin light chain 4
chr8_+_145203548 0.75 ENST00000534366.1
MROH1
maestro heat-like repeat family member 1
chr9_+_131217459 0.75 ENST00000497812.2
ENST00000393533.2
ODF2
outer dense fiber of sperm tails 2
chr3_+_160559931 0.73 ENST00000464260.1
ENST00000295839.9
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr10_+_114135004 0.72 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr21_+_34697209 0.71 ENST00000270139.3
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr3_+_185046676 0.71 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr8_-_27468842 0.70 ENST00000523500.1
CLU
clusterin
chr7_+_150521691 0.70 ENST00000493429.1
AOC1
amine oxidase, copper containing 1
chr1_+_109102652 0.69 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr9_-_14313893 0.69 ENST00000380921.3
ENST00000380959.3
NFIB
nuclear factor I/B
chr15_+_41057818 0.68 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr9_+_74764278 0.68 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr3_-_114790179 0.66 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr7_+_99933730 0.66 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr5_+_140027355 0.66 ENST00000417647.2
ENST00000507593.1
ENST00000508301.1
IK
IK cytokine, down-regulator of HLA II
chr1_-_20126365 0.65 ENST00000294543.6
ENST00000375122.2
TMCO4
transmembrane and coiled-coil domains 4
chr1_-_151798546 0.65 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr11_-_5462744 0.62 ENST00000380211.1
OR51I1
olfactory receptor, family 51, subfamily I, member 1
chr14_-_90085458 0.62 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr11_+_113185292 0.61 ENST00000429951.1
ENST00000442859.1
ENST00000531164.1
ENST00000529850.1
ENST00000314756.3
ENST00000525965.1
TTC12
tetratricopeptide repeat domain 12
chr7_-_69062391 0.61 ENST00000436600.2
RP5-942I16.1
RP5-942I16.1
chr7_-_150777874 0.61 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr6_-_31697977 0.61 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr6_+_28109703 0.61 ENST00000457389.2
ENST00000330236.6
ZKSCAN8
zinc finger with KRAB and SCAN domains 8
chr16_-_5147743 0.60 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
FAM86A
family with sequence similarity 86, member A
chr3_+_51976338 0.58 ENST00000417220.2
ENST00000431474.1
ENST00000398755.3
PARP3
poly (ADP-ribose) polymerase family, member 3
chr1_-_112032284 0.57 ENST00000414219.1
ADORA3
adenosine A3 receptor
chr17_-_40729681 0.56 ENST00000590760.1
ENST00000587209.1
ENST00000393795.3
ENST00000253789.5
PSMC3IP
PSMC3 interacting protein
chr2_-_207024233 0.56 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_-_48866517 0.56 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr4_-_54457783 0.55 ENST00000263925.7
ENST00000512247.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr11_-_73720122 0.54 ENST00000426995.2
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr16_+_20817761 0.54 ENST00000568046.1
ENST00000261377.6
AC004381.6
Putative RNA exonuclease NEF-sp
chr22_-_24181174 0.54 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr7_-_150777949 0.52 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr8_-_17555164 0.52 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr19_-_43586820 0.51 ENST00000406487.1
PSG2
pregnancy specific beta-1-glycoprotein 2
chr16_+_30759700 0.51 ENST00000328273.7
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr7_-_150777920 0.51 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr2_-_60780702 0.51 ENST00000359629.5
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr3_+_171561127 0.51 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr1_-_154928562 0.51 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr14_-_106453155 0.50 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr11_+_30344595 0.50 ENST00000282032.3
ARL14EP
ADP-ribosylation factor-like 14 effector protein
chr9_+_976964 0.50 ENST00000190165.2
DMRT3
doublesex and mab-3 related transcription factor 3
chr10_-_71892555 0.48 ENST00000307864.1
AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr2_+_97426631 0.48 ENST00000377075.2
CNNM4
cyclin M4
chr11_-_64764435 0.47 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr12_+_50017184 0.47 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr12_+_9980069 0.47 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr11_+_113185533 0.45 ENST00000393020.1
TTC12
tetratricopeptide repeat domain 12
chr9_-_14313641 0.44 ENST00000380953.1
NFIB
nuclear factor I/B
chr11_-_104480019 0.42 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr10_+_89419370 0.42 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr14_+_89029253 0.41 ENST00000251038.5
ENST00000359301.3
ENST00000302216.8
ZC3H14
zinc finger CCCH-type containing 14
chr14_-_106963409 0.40 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr16_+_30759563 0.40 ENST00000563588.1
ENST00000565924.1
ENST00000424889.3
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr2_-_60780536 0.40 ENST00000538214.1
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr3_+_73045936 0.39 ENST00000356692.5
ENST00000488810.1
ENST00000394284.3
ENST00000295862.9
ENST00000495566.1
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr16_-_12897642 0.39 ENST00000433677.2
ENST00000261660.4
ENST00000381774.4
CPPED1
calcineurin-like phosphoesterase domain containing 1
chr18_-_74728998 0.39 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr7_+_37960163 0.39 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1
ependymin related 1
chr9_-_15307200 0.38 ENST00000506891.1
ENST00000541445.1
ENST00000512701.2
ENST00000380850.4
ENST00000297615.5
ENST00000355694.2
TTC39B
tetratricopeptide repeat domain 39B
chr10_-_70092671 0.37 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr12_-_7261772 0.37 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr22_+_30163340 0.36 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr3_-_139396853 0.36 ENST00000406164.1
ENST00000406824.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr4_-_57253587 0.35 ENST00000513376.1
ENST00000602986.1
ENST00000434343.2
ENST00000451613.1
ENST00000205214.6
ENST00000502617.1
AASDH
aminoadipate-semialdehyde dehydrogenase
chr8_+_42396936 0.35 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr7_-_56160625 0.34 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr10_+_81107271 0.34 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr11_-_68519026 0.34 ENST00000255087.5
MTL5
metallothionein-like 5, testis-specific (tesmin)
chr14_+_74058410 0.33 ENST00000326303.4
ACOT4
acyl-CoA thioesterase 4
chr5_-_140027175 0.33 ENST00000512088.1
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr1_+_19923454 0.33 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1
MINOS1
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr1_-_44818599 0.33 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr7_-_99332719 0.32 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr5_-_140027357 0.32 ENST00000252102.4
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr1_-_207224307 0.32 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr6_+_46761118 0.31 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr5_-_135231516 0.31 ENST00000274520.1
IL9
interleukin 9
chr2_-_175711133 0.31 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chrX_+_22050546 0.31 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr3_-_139396787 0.30 ENST00000296202.7
ENST00000509291.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr3_+_137906109 0.30 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8
armadillo repeat containing 8
chr1_-_147245484 0.30 ENST00000271348.2
GJA5
gap junction protein, alpha 5, 40kDa
chr22_-_50217981 0.30 ENST00000457780.2
BRD1
bromodomain containing 1
chr14_-_96180435 0.29 ENST00000556450.1
ENST00000555202.1
ENST00000554012.1
ENST00000402399.1
TCL1A
T-cell leukemia/lymphoma 1A
chr19_-_7293942 0.29 ENST00000341500.5
ENST00000302850.5
INSR
insulin receptor
chr17_-_8198636 0.29 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr6_+_107349392 0.29 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
C6orf203
chromosome 6 open reading frame 203
chr11_+_111957497 0.29 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr11_+_71935797 0.28 ENST00000298229.2
ENST00000541756.1
INPPL1
inositol polyphosphate phosphatase-like 1
chr11_-_16430399 0.28 ENST00000528252.1
SOX6
SRY (sex determining region Y)-box 6
chr16_+_31128978 0.28 ENST00000448516.2
ENST00000219797.4
KAT8
K(lysine) acetyltransferase 8
chr1_+_40997233 0.27 ENST00000372699.3
ENST00000372697.3
ENST00000372696.3
ZNF684
zinc finger protein 684
chr9_-_14314518 0.27 ENST00000397581.2
NFIB
nuclear factor I/B
chr9_-_114362093 0.27 ENST00000538962.1
ENST00000407693.2
ENST00000238248.3
PTGR1
prostaglandin reductase 1
chr21_+_43639211 0.27 ENST00000450121.1
ENST00000398449.3
ENST00000361802.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr3_+_37427760 0.27 ENST00000425932.1
C3orf35
chromosome 3 open reading frame 35
chr10_+_70480963 0.26 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1
cell division cycle and apoptosis regulator 1
chr1_-_226111929 0.26 ENST00000343818.6
ENST00000432920.2
PYCR2
RP4-559A3.7
pyrroline-5-carboxylate reductase family, member 2
Uncharacterized protein
chr13_+_111766897 0.26 ENST00000317133.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr10_+_114710516 0.26 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr17_+_47448102 0.26 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr15_+_76629064 0.26 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr19_-_22193731 0.25 ENST00000601773.1
ENST00000397126.4
ENST00000601993.1
ENST00000599916.1
ZNF208
zinc finger protein 208
chr5_-_93447333 0.25 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr10_+_116853091 0.25 ENST00000526946.1
ATRNL1
attractin-like 1
chr9_-_125590818 0.25 ENST00000259467.4
PDCL
phosducin-like
chr2_-_197226875 0.24 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr19_-_11669960 0.24 ENST00000589171.1
ENST00000590700.1
ENST00000586683.1
ENST00000593077.1
ENST00000252445.3
ELOF1
elongation factor 1 homolog (S. cerevisiae)
chr3_-_139396801 0.24 ENST00000413939.2
ENST00000339837.5
ENST00000512391.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr3_-_58613323 0.24 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr1_-_202679535 0.24 ENST00000367268.4
SYT2
synaptotagmin II
chr16_-_69448 0.23 ENST00000326592.9
WASH4P
WAS protein family homolog 4 pseudogene
chr11_+_3876859 0.23 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr8_+_103563792 0.23 ENST00000285402.3
ODF1
outer dense fiber of sperm tails 1
chr10_+_85933494 0.23 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr2_+_234296792 0.22 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr2_+_69240415 0.22 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr19_+_41699135 0.22 ENST00000542619.1
ENST00000600561.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr8_-_38126675 0.22 ENST00000531823.1
ENST00000534339.1
ENST00000524616.1
ENST00000422581.2
ENST00000424479.2
ENST00000419686.2
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr2_-_42721110 0.21 ENST00000394973.4
ENST00000306078.1
KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr9_-_14314066 0.21 ENST00000397575.3
NFIB
nuclear factor I/B
chr9_+_4662282 0.20 ENST00000381883.2
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr6_-_42690312 0.20 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chr18_-_10701979 0.20 ENST00000538948.1
ENST00000285141.4
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr1_-_207095212 0.20 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr22_-_50218452 0.20 ENST00000216267.8
BRD1
bromodomain containing 1
chr4_+_667307 0.20 ENST00000506838.1
MYL5
myosin, light chain 5, regulatory
chr17_+_73089382 0.20 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr13_+_33160553 0.20 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr4_-_186732048 0.19 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr19_-_43690674 0.19 ENST00000342951.6
ENST00000366175.3
PSG5
pregnancy specific beta-1-glycoprotein 5
chr2_+_69240511 0.18 ENST00000409349.3
ANTXR1
anthrax toxin receptor 1
chr17_+_8243154 0.18 ENST00000328248.2
ENST00000584943.1
ODF4
outer dense fiber of sperm tails 4
chr17_+_18087553 0.18 ENST00000399138.4
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr5_+_52285144 0.18 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr4_+_7045042 0.18 ENST00000310074.7
ENST00000512388.1
TADA2B
transcriptional adaptor 2B
chr5_-_140700322 0.17 ENST00000313368.5
TAF7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:1904800 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.7 2.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.5 1.4 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.4 1.6 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.4 1.9 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.3 0.9 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.3 0.9 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.3 1.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 2.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 0.8 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 0.8 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 1.6 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 1.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.7 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.2 0.9 GO:0061760 antifungal innate immune response(GO:0061760)
0.2 1.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 0.9 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.2 4.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 1.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 0.9 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.6 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.1 1.2 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 2.9 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.4 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.7 GO:0071504 cellular response to heparin(GO:0071504)
0.1 0.3 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.3 GO:0003193 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.9 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.4 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.3 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.8 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.3 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.1 0.3 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.1 0.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.4 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.9 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.1 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 0.2 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.2 GO:0019254 amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 1.1 GO:0015671 oxygen transport(GO:0015671)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 1.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.6 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 1.0 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.6 GO:0006527 arginine catabolic process(GO:0006527)
0.0 2.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.3 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.6 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.7 GO:0060850 cellular response to sterol(GO:0036315) regulation of transcription involved in cell fate commitment(GO:0060850)
0.0 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.6 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.2 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 1.1 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.2 GO:0015846 polyamine transport(GO:0015846)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.2 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.5 GO:0042832 defense response to protozoan(GO:0042832)
0.0 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0035234 luteolysis(GO:0001554) ectopic germ cell programmed cell death(GO:0035234)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.1 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.9 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.3 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 1.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.9 GO:0036156 inner dynein arm(GO:0036156)
0.2 1.6 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.6 GO:0097224 sperm connecting piece(GO:0097224)
0.1 1.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.9 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.8 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.9 GO:0044326 dendritic spine neck(GO:0044326)
0.1 1.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.6 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 1.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.2 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.3 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.1 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.1 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 1.4 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 1.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 2.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.4 1.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.3 1.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 1.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.3 0.8 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.3 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 2.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 0.7 GO:0019961 interferon binding(GO:0019961)
0.2 0.7 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.2 4.9 GO:0070330 aromatase activity(GO:0070330)
0.2 1.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 0.9 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.2 1.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.4 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.3 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.6 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.9 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 1.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.3 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 1.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.6 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 1.9 GO:0019239 deaminase activity(GO:0019239)
0.0 1.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.7 GO:0048038 quinone binding(GO:0048038)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 1.1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 1.1 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 3.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis