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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for OLIG1

Z-value: 0.54

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Transcription factors associated with OLIG1

Gene Symbol Gene ID Gene Info
ENSG00000184221.8 oligodendrocyte transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OLIG1hg19_v2_chr21_+_34442439_344424550.412.4e-02Click!

Activity profile of OLIG1 motif

Sorted Z-values of OLIG1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_158345462 1.64 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr4_+_69313145 1.43 ENST00000305363.4
transmembrane protease, serine 11E
chr19_-_51472222 1.40 ENST00000376851.3
kallikrein-related peptidase 6
chr19_-_51472823 1.35 ENST00000310157.2
kallikrein-related peptidase 6
chrX_+_69509927 1.07 ENST00000374403.3
kinesin family member 4A
chr4_+_144354644 0.99 ENST00000512843.1
GRB2-associated binding protein 1
chr1_-_153029980 0.97 ENST00000392653.2
small proline-rich protein 2A
chr5_+_68485433 0.85 ENST00000502689.1
centromere protein H
chr15_+_63354769 0.78 ENST00000558910.1
tropomyosin 1 (alpha)
chr2_+_210444748 0.78 ENST00000392194.1
microtubule-associated protein 2
chr1_+_153750622 0.69 ENST00000532853.1
solute carrier family 27 (fatty acid transporter), member 3
chr2_-_165424973 0.68 ENST00000543549.1
growth factor receptor-bound protein 14
chr3_+_42897512 0.68 ENST00000493193.1
atypical chemokine receptor 2
chr8_-_95449155 0.60 ENST00000481490.2
fibrinogen silencer binding protein
chr11_+_94501497 0.59 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
angiomotin like 1
chr1_+_196743943 0.58 ENST00000471440.2
ENST00000391985.3
complement factor H-related 3
chr14_-_55658252 0.57 ENST00000395425.2
discs, large (Drosophila) homolog-associated protein 5
chr4_-_159094194 0.55 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr6_+_69942298 0.55 ENST00000238918.8
brain-specific angiogenesis inhibitor 3
chr2_+_108994633 0.53 ENST00000409309.3
sulfotransferase family, cytosolic, 1C, member 4
chr2_+_108994466 0.52 ENST00000272452.2
sulfotransferase family, cytosolic, 1C, member 4
chr1_+_152881014 0.51 ENST00000368764.3
ENST00000392667.2
involucrin
chr10_+_133918175 0.50 ENST00000298622.4
Janus kinase and microtubule interacting protein 3
chr14_-_55658323 0.50 ENST00000554067.1
ENST00000247191.2
discs, large (Drosophila) homolog-associated protein 5
chr9_+_5450503 0.49 ENST00000381573.4
ENST00000381577.3
CD274 molecule
chr5_+_68485363 0.48 ENST00000283006.2
ENST00000515001.1
centromere protein H
chr2_-_32490801 0.48 ENST00000360906.5
ENST00000342905.6
NLR family, CARD domain containing 4
chrX_+_64887512 0.48 ENST00000360270.5
moesin
chr14_-_106494587 0.47 ENST00000390597.2
immunoglobulin heavy variable 2-5
chr6_+_53948328 0.47 ENST00000370876.2
muscular LMNA-interacting protein
chr16_+_14726672 0.45 ENST00000261658.2
ENST00000563971.1
bifunctional apoptosis regulator
chr11_+_118175132 0.45 ENST00000361763.4
CD3e molecule, epsilon (CD3-TCR complex)
chr2_-_32490859 0.43 ENST00000404025.2
NLR family, CARD domain containing 4
chr18_+_21529811 0.43 ENST00000588004.1
laminin, alpha 3
chr11_+_118175596 0.43 ENST00000528600.1
CD3e molecule, epsilon (CD3-TCR complex)
chr5_+_135496675 0.43 ENST00000507637.1
SMAD family member 5
chr12_+_82347498 0.42 ENST00000550506.1
RP11-362A1.1
chr11_+_60163775 0.41 ENST00000300187.6
ENST00000395005.2
membrane-spanning 4-domains, subfamily A, member 14
chr11_-_101454658 0.41 ENST00000344327.3
transient receptor potential cation channel, subfamily C, member 6
chr11_+_65405556 0.41 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1
chr1_+_244515930 0.40 ENST00000366537.1
ENST00000308105.4
chromosome 1 open reading frame 100
chr19_+_18496957 0.38 ENST00000252809.3
growth differentiation factor 15
chr17_-_34344991 0.38 ENST00000591423.1
chemokine (C-C motif) ligand 23
chr1_+_17559776 0.37 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
peptidyl arginine deiminase, type I
chr3_-_128690173 0.35 ENST00000508239.1
Uncharacterized protein FLJ43738
chr2_-_182545603 0.34 ENST00000295108.3
neuronal differentiation 1
chr2_+_223162866 0.33 ENST00000295226.1
coiled-coil domain containing 140
chr18_-_50240 0.33 ENST00000573909.1
Tubulin beta-8 chain-like protein LOC260334
chr7_+_110731062 0.32 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr17_+_73629500 0.32 ENST00000375215.3
small integral membrane protein 5
chr2_-_166930131 0.31 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
sodium channel, voltage-gated, type I, alpha subunit
chr12_-_75723805 0.30 ENST00000409799.1
ENST00000409445.3
calcyphosine 2
chr11_+_60163918 0.30 ENST00000526375.1
ENST00000531783.1
ENST00000395001.1
membrane-spanning 4-domains, subfamily A, member 14
chr7_-_112758589 0.30 ENST00000413744.1
ENST00000439551.1
ENST00000441359.1
long intergenic non-protein coding RNA 998
chr17_+_60758814 0.30 ENST00000579432.1
ENST00000446119.2
mannose receptor, C type 2
chr8_+_70378852 0.30 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
sulfatase 1
chr2_-_97760576 0.29 ENST00000414820.1
ENST00000272610.3
fumarylacetoacetate hydrolase domain containing 2B
chr11_+_134123389 0.29 ENST00000281182.4
ENST00000537423.1
ENST00000543332.1
ENST00000374752.4
acyl-CoA dehydrogenase family, member 8
chr4_-_99064387 0.29 ENST00000295268.3
sperm-tail PG-rich repeat containing 2
chr7_-_112758665 0.29 ENST00000397764.3
long intergenic non-protein coding RNA 998
chr18_-_49557 0.29 ENST00000308911.6
Tubulin beta-8 chain-like protein LOC260334
chr12_+_26348429 0.29 ENST00000242729.2
sarcospan
chr17_-_7017559 0.29 ENST00000446679.2
asialoglycoprotein receptor 2
chr5_-_75919253 0.28 ENST00000296641.4
coagulation factor II (thrombin) receptor-like 2
chrX_+_70798261 0.28 ENST00000373696.3
acidic repeat containing
chr7_-_88425025 0.27 ENST00000297203.2
chromosome 7 open reading frame 62
chr16_+_12059091 0.27 ENST00000562385.1
tumor necrosis factor receptor superfamily, member 17
chr15_+_26360970 0.27 ENST00000556159.1
ENST00000557523.1
long intergenic non-protein coding RNA 929
chr3_+_49840685 0.27 ENST00000333323.4
family with sequence similarity 212, member A
chr18_-_44561988 0.26 ENST00000332567.4
transcription elongation factor B polypeptide 3B (elongin A2)
chr4_-_69111401 0.26 ENST00000332644.5
transmembrane protease, serine 11B
chr1_-_231560790 0.25 ENST00000366641.3
egl-9 family hypoxia-inducible factor 1
chr1_+_196857144 0.24 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
complement factor H-related 4
chr1_+_196743912 0.24 ENST00000367425.4
complement factor H-related 3
chr1_+_15479021 0.24 ENST00000428417.1
transmembrane protein 51
chr3_-_178984759 0.24 ENST00000349697.2
ENST00000497599.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr18_+_44812072 0.23 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
chr17_+_41003166 0.23 ENST00000308423.2
amine oxidase, copper containing 3
chr22_+_23089870 0.23 ENST00000390311.2
immunoglobulin lambda variable 3-16
chr19_-_11450249 0.23 ENST00000222120.3
RAB3D, member RAS oncogene family
chr16_-_420338 0.23 ENST00000450882.1
ENST00000441883.1
ENST00000447696.1
ENST00000389675.2
mitochondrial ribosomal protein L28
chr11_+_59824060 0.23 ENST00000395032.2
ENST00000358152.2
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr11_-_26743546 0.22 ENST00000280467.6
ENST00000396005.3
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr16_+_2016821 0.22 ENST00000569210.2
ENST00000569714.1
ring finger protein 151
chr2_+_177053307 0.22 ENST00000331462.4
homeobox D1
chr4_+_71600144 0.22 ENST00000502653.1
RUN and FYVE domain containing 3
chr2_+_201994208 0.22 ENST00000440180.1
CASP8 and FADD-like apoptosis regulator
chr12_-_52800139 0.22 ENST00000257974.2
keratin 82
chr20_+_31805131 0.22 ENST00000375454.3
ENST00000375452.3
BPI fold containing family A, member 3
chr11_-_88796803 0.22 ENST00000418177.2
ENST00000455756.2
glutamate receptor, metabotropic 5
chr1_+_15479054 0.21 ENST00000376014.3
ENST00000451326.2
transmembrane protein 51
chr1_+_87458692 0.21 ENST00000370548.2
ENST00000356813.4
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr17_-_47925379 0.21 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
tachykinin 4 (hemokinin)
chr5_+_157158205 0.21 ENST00000231198.7
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr5_-_137674000 0.21 ENST00000510119.1
ENST00000513970.1
cell division cycle 25C
chr11_+_30252549 0.21 ENST00000254122.3
ENST00000417547.1
follicle stimulating hormone, beta polypeptide
chr19_-_46999755 0.21 ENST00000599531.1
paraneoplastic Ma antigen family-like 2
chr2_+_90108504 0.20 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_+_11674213 0.20 ENST00000381486.2
growth regulation by estrogen in breast cancer 1
chr18_+_77623668 0.20 ENST00000316249.3
potassium voltage-gated channel, subfamily G, member 2
chr7_+_4721885 0.20 ENST00000328914.4
forkhead box K1
chr3_+_112709804 0.20 ENST00000383677.3
GTP-binding protein 8 (putative)
chr22_+_24999114 0.20 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
gamma-glutamyltransferase 1
chr20_-_29994007 0.20 ENST00000376314.2
defensin, beta 121
chrX_+_107288239 0.20 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr12_+_117348742 0.19 ENST00000309909.5
ENST00000455858.2
F-box and WD repeat domain containing 8
chr12_+_10124001 0.19 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
C-type lectin domain family 12, member A
chr3_+_151451707 0.19 ENST00000356517.3
arylacetamide deacetylase-like 2
chr5_-_150460539 0.19 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNFAIP3 interacting protein 1
chr16_+_21716284 0.19 ENST00000388957.3
otoancorin
chr10_+_5135981 0.19 ENST00000380554.3
aldo-keto reductase family 1, member C3
chrX_+_107288197 0.19 ENST00000415430.3
V-set and immunoglobulin domain containing 1
chr17_-_39538550 0.19 ENST00000394001.1
keratin 34
chr22_+_36113919 0.18 ENST00000249044.2
apolipoprotein L, 5
chr6_-_25874440 0.18 ENST00000361703.6
ENST00000397060.4
solute carrier family 17 (organic anion transporter), member 3
chr3_-_196911002 0.18 ENST00000452595.1
discs, large homolog 1 (Drosophila)
chr3_-_196910721 0.18 ENST00000443183.1
discs, large homolog 1 (Drosophila)
chr10_+_5238793 0.18 ENST00000263126.1
aldo-keto reductase family 1, member C4
chrX_+_2670066 0.18 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
Xg blood group
chr11_-_111741994 0.18 ENST00000398006.2
ALG9, alpha-1,2-mannosyltransferase
chr16_+_31119615 0.18 ENST00000394950.3
ENST00000287507.3
ENST00000219794.6
ENST00000561755.1
branched chain ketoacid dehydrogenase kinase
chr20_-_30060816 0.18 ENST00000317676.2
defensin, beta 124
chr17_-_58469687 0.17 ENST00000590133.1
ubiquitin specific peptidase 32
chr20_+_34556488 0.17 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
cyclic nucleotide binding domain containing 2
chr20_-_44144249 0.17 ENST00000217428.6
serine peptidase inhibitor, Kunitz type, 3
chr4_-_170948361 0.17 ENST00000393702.3
microfibrillar-associated protein 3-like
chr1_+_110881945 0.17 ENST00000602849.1
ENST00000487146.2
RNA binding motif protein 15
chr5_-_171433579 0.17 ENST00000265094.5
ENST00000393802.2
F-box and WD repeat domain containing 11
chr17_-_47286729 0.16 ENST00000300406.2
ENST00000511277.1
ENST00000511673.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr7_-_121784285 0.16 ENST00000417368.2
aminoadipate-semialdehyde synthase
chr3_+_37441062 0.16 ENST00000426078.1
chromosome 3 open reading frame 35
chr2_+_191792376 0.15 ENST00000409428.1
ENST00000409215.1
glutaminase
chr6_+_57182400 0.15 ENST00000607273.1
primase, DNA, polypeptide 2 (58kDa)
chr17_+_42923686 0.15 ENST00000591513.1
HIG1 hypoxia inducible domain family, member 1B
chr10_-_5446786 0.15 ENST00000479328.1
ENST00000380419.3
tubulin, alpha-like 3
chr19_+_39390320 0.15 ENST00000576510.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr3_+_35722424 0.15 ENST00000396481.2
cAMP-regulated phosphoprotein, 21kDa
chr4_-_41216619 0.15 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
amyloid beta (A4) precursor protein-binding, family B, member 2
chr19_+_45542773 0.15 ENST00000544944.2
CLK4-associating serine/arginine rich protein
chr1_+_169764163 0.15 ENST00000413811.2
ENST00000359326.4
ENST00000456684.1
chromosome 1 open reading frame 112
chr3_+_185300391 0.15 ENST00000545472.1
SUMO1/sentrin/SMT3 specific peptidase 2
chr5_-_171433819 0.14 ENST00000296933.6
F-box and WD repeat domain containing 11
chr19_-_20150301 0.14 ENST00000397165.2
zinc finger protein 682
chr6_+_24126350 0.14 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
neurensin 1
chr11_+_89764274 0.14 ENST00000448984.1
ENST00000432771.1
tripartite motif containing 49C
chrX_+_76709648 0.14 ENST00000439435.1
fibroblast growth factor 16
chr3_+_37440653 0.14 ENST00000328376.5
ENST00000452017.2
chromosome 3 open reading frame 35
chr2_+_74361599 0.14 ENST00000401851.1
MGC10955
chr4_+_118955500 0.14 ENST00000296499.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr5_-_115872142 0.14 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_+_166428839 0.13 ENST00000342316.4
cysteine-serine-rich nuclear protein 3
chr3_+_62936098 0.13 ENST00000475886.1
ENST00000465684.1
ENST00000465262.1
ENST00000468072.1
long intergenic non-protein coding RNA 698
chr2_+_219840955 0.13 ENST00000598002.1
ENST00000432733.1
long intergenic non-protein coding RNA 608
chr12_+_4699244 0.13 ENST00000540757.2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr1_+_158149737 0.13 ENST00000368171.3
CD1d molecule
chr4_-_113207048 0.13 ENST00000361717.3
TRAF-interacting protein with forkhead-associated domain
chr1_+_20617362 0.13 ENST00000375079.2
ENST00000289815.8
ENST00000375083.4
ENST00000289825.4
von Willebrand factor A domain containing 5B1
chr6_+_73076432 0.12 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr9_-_127177703 0.12 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
proteasome (prosome, macropain) subunit, beta type, 7
chr10_-_11574274 0.12 ENST00000277575.5
USP6 N-terminal like
chr1_+_100810575 0.12 ENST00000542213.1
cell division cycle 14A
chr19_-_42806919 0.12 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr18_+_55018044 0.12 ENST00000324000.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chrX_+_118108601 0.12 ENST00000371628.3
LON peptidase N-terminal domain and ring finger 3
chrX_-_13338518 0.12 ENST00000380622.2
ataxin 3-like
chr2_+_201994042 0.12 ENST00000417748.1
CASP8 and FADD-like apoptosis regulator
chr10_-_1071796 0.12 ENST00000277517.1
isopentenyl-diphosphate delta isomerase 2
chrX_+_118108571 0.12 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr19_+_15904761 0.11 ENST00000308940.8
olfactory receptor, family 10, subfamily H, member 5
chr2_+_152214098 0.11 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr1_-_45253377 0.11 ENST00000372207.3
bestrophin 4
chr5_-_11589131 0.11 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chrX_-_30877837 0.11 ENST00000378930.3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr7_+_114562909 0.11 ENST00000423503.1
ENST00000427207.1
MyoD family inhibitor domain containing
chr4_+_88720698 0.11 ENST00000226284.5
integrin-binding sialoprotein
chr4_-_174320687 0.11 ENST00000296506.3
stimulator of chondrogenesis 1
chr7_-_11871815 0.11 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr10_-_69597828 0.11 ENST00000339758.7
DnaJ (Hsp40) homolog, subfamily C, member 12
chr12_-_123450986 0.11 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr6_+_97010424 0.10 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
four and a half LIM domains 5
chr11_+_55650773 0.10 ENST00000449290.2
tripartite motif-containing 51
chr18_-_29340827 0.10 ENST00000269205.5
solute carrier family 25, member 52
chr15_-_38519066 0.10 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
chr4_-_100575781 0.10 ENST00000511828.1
Protein LOC285556
chr2_+_220462560 0.10 ENST00000456909.1
ENST00000295641.10
serine/threonine kinase 11 interacting protein
chr8_-_124279627 0.10 ENST00000357082.4
ZHX1-C8ORF76 readthrough
chr19_+_55417499 0.10 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
natural cytotoxicity triggering receptor 1
chr3_+_119298429 0.10 ENST00000478927.1
ADP-ribosylarginine hydrolase
chr3_-_58200398 0.10 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
deoxyribonuclease I-like 3
chr6_+_292051 0.10 ENST00000344450.5
dual specificity phosphatase 22
chr22_+_20105259 0.10 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr1_+_50569575 0.10 ENST00000371827.1
ELAV like neuron-specific RNA binding protein 4
chr2_+_90458201 0.10 ENST00000603238.1
Uncharacterized protein
chr3_-_107777208 0.10 ENST00000398258.3
CD47 molecule
chr2_+_201994569 0.10 ENST00000457277.1
CASP8 and FADD-like apoptosis regulator
chr6_-_160147925 0.10 ENST00000535561.1
superoxide dismutase 2, mitochondrial
chr7_-_44530479 0.10 ENST00000355451.7
NudC domain containing 3
chrX_+_55649833 0.10 ENST00000339140.3
forkhead box R2
chr11_-_59612969 0.09 ENST00000541311.1
ENST00000257248.2
gastric intrinsic factor (vitamin B synthesis)
chr4_-_153456153 0.09 ENST00000603548.1
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.2 0.9 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 0.5 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 2.7 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.9 GO:0070269 pyroptosis(GO:0070269)
0.1 0.8 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 1.3 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.4 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 1.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.5 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.1 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.4 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.4 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 1.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.0 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.1 GO:0033076 alkaloid catabolic process(GO:0009822) isoquinoline alkaloid metabolic process(GO:0033076) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.6 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.0 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.0 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.9 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0032059 muscle thin filament tropomyosin(GO:0005862) bleb(GO:0032059)
0.0 0.1 GO:0097181 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.7 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 1.1 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.2 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.5 GO:0089720 caspase binding(GO:0089720)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.4 PID EPO PATHWAY EPO signaling pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)