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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for OLIG3_NEUROD2_NEUROG2

Z-value: 0.91

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Transcription factors associated with OLIG3_NEUROD2_NEUROG2

Gene Symbol Gene ID Gene Info
ENSG00000177468.5 oligodendrocyte transcription factor 3
ENSG00000171532.4 neuronal differentiation 2
ENSG00000178403.3 neurogenin 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OLIG3hg19_v2_chr6_-_137815524_137815537-0.301.0e-01Click!
NEUROG2hg19_v2_chr4_-_113437328_113437337-0.154.2e-01Click!
NEUROD2hg19_v2_chr17_-_37764128_37764258-0.009.9e-01Click!

Activity profile of OLIG3_NEUROD2_NEUROG2 motif

Sorted Z-values of OLIG3_NEUROD2_NEUROG2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_130635741 3.86 ENST00000223836.10
adenylate kinase 1
chr12_-_91573132 2.63 ENST00000550563.1
ENST00000546370.1
decorin
chr16_-_55867146 2.63 ENST00000422046.2
carboxylesterase 1
chr1_+_104293028 2.32 ENST00000370079.3
amylase, alpha 1C (salivary)
chr4_+_69962185 1.75 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_+_69962212 1.75 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr15_-_65503801 1.66 ENST00000261883.4
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr1_+_47489240 1.65 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr17_+_7211280 1.64 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
eukaryotic translation initiation factor 5A
chr6_+_32407619 1.62 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr2_-_154335300 1.62 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr17_+_7211656 1.57 ENST00000416016.2
eukaryotic translation initiation factor 5A
chr20_-_32031680 1.51 ENST00000217381.2
syntrophin, alpha 1
chr15_-_45670924 1.46 ENST00000396659.3
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr3_+_63638339 1.45 ENST00000343837.3
ENST00000469440.1
sentan, cilia apical structure protein
chr5_-_111312622 1.37 ENST00000395634.3
neuronal regeneration related protein
chr3_-_131753830 1.29 ENST00000429747.1
copine IV
chr17_-_8770956 1.19 ENST00000311434.9
phosphoinositide-3-kinase, regulatory subunit 6
chr4_+_75858318 1.18 ENST00000307428.7
prostate androgen-regulated mucin-like protein 1
chr4_+_75858290 1.14 ENST00000513238.1
prostate androgen-regulated mucin-like protein 1
chr7_-_99573640 1.09 ENST00000411734.1
alpha-2-glycoprotein 1, zinc-binding
chr12_+_56862301 1.08 ENST00000338146.5
SPRY domain containing 4
chr14_-_107283278 1.07 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr19_-_52227221 1.07 ENST00000222115.1
ENST00000540069.2
hyaluronan synthase 1
chr1_-_152131703 1.06 ENST00000316073.3
repetin
chr12_+_54393880 1.03 ENST00000303450.4
homeobox C9
chr1_+_205538105 0.99 ENST00000367147.4
ENST00000539267.1
major facilitator superfamily domain containing 4
chr17_-_4689649 0.98 ENST00000441199.2
ENST00000416307.2
vitelline membrane outer layer 1 homolog (chicken)
chr1_-_144994909 0.97 ENST00000369347.4
ENST00000369354.3
phosphodiesterase 4D interacting protein
chr17_-_4689727 0.91 ENST00000328739.5
ENST00000354194.4
vitelline membrane outer layer 1 homolog (chicken)
chr3_+_113251143 0.91 ENST00000264852.4
ENST00000393830.3
SID1 transmembrane family, member 1
chr16_-_69385681 0.91 ENST00000288025.3
transmembrane emp24 protein transport domain containing 6
chr1_+_95975672 0.88 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
chr12_-_91573316 0.88 ENST00000393155.1
decorin
chr20_-_34117447 0.87 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
chromosome 20 open reading frame 173
chr1_+_220863187 0.84 ENST00000294889.5
chromosome 1 open reading frame 115
chr8_-_23315190 0.79 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
ectonucleoside triphosphate diphosphohydrolase 4
chr7_-_99573677 0.79 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr15_-_98417780 0.77 ENST00000503874.3
long intergenic non-protein coding RNA 923
chr19_+_41594377 0.76 ENST00000330436.3
cytochrome P450, family 2, subfamily A, polypeptide 13
chr10_-_61495760 0.75 ENST00000395347.1
solute carrier family 16, member 9
chr11_-_2182388 0.75 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
insulin
INS-IGF2 readthrough
chr15_-_55700522 0.73 ENST00000564092.1
ENST00000310958.6
cell cycle progression 1
chr10_-_123357598 0.73 ENST00000358487.5
ENST00000369058.3
ENST00000369060.4
ENST00000359354.2
fibroblast growth factor receptor 2
chr7_+_90893783 0.72 ENST00000287934.2
frizzled family receptor 1
chr15_-_55700216 0.72 ENST00000569205.1
cell cycle progression 1
chr1_+_186344883 0.71 ENST00000367470.3
chromosome 1 open reading frame 27
chr5_+_140571902 0.71 ENST00000239446.4
protocadherin beta 10
chr11_+_120107344 0.70 ENST00000260264.4
POU class 2 homeobox 3
chr5_+_101569696 0.70 ENST00000597120.1
AC008948.1
chr16_-_20364122 0.69 ENST00000396138.4
ENST00000577168.1
uromodulin
chr19_+_56368803 0.67 ENST00000587891.1
NLR family, pyrin domain containing 4
chr10_+_51565188 0.67 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
nuclear receptor coactivator 4
chr1_-_144995074 0.67 ENST00000534536.1
phosphodiesterase 4D interacting protein
chr19_-_54876558 0.64 ENST00000391742.2
ENST00000434277.2
leukocyte-associated immunoglobulin-like receptor 1
chr18_-_10748498 0.64 ENST00000579949.1
piezo-type mechanosensitive ion channel component 2
chr7_-_55930443 0.64 ENST00000388975.3
septin 14
chr1_+_186344945 0.62 ENST00000419367.3
ENST00000287859.6
chromosome 1 open reading frame 27
chr15_+_62853562 0.62 ENST00000561311.1
talin 2
chr10_-_48055018 0.62 ENST00000426610.2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2C
chr19_+_18208603 0.62 ENST00000262811.6
microtubule associated serine/threonine kinase 3
chr11_+_27076764 0.62 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_+_23313591 0.62 ENST00000343070.2
sodium channel, non-voltage-gated 1, beta subunit
chr4_+_160188889 0.62 ENST00000264431.4
Rap guanine nucleotide exchange factor (GEF) 2
chr9_-_75567962 0.58 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr18_-_74839891 0.58 ENST00000581878.1
myelin basic protein
chr3_-_122102065 0.58 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
coiled-coil domain containing 58
chr9_+_12775011 0.57 ENST00000319264.3
leucine rich adaptor protein 1-like
chr6_-_33714752 0.57 ENST00000451316.1
inositol hexakisphosphate kinase 3
chr16_-_72206034 0.56 ENST00000537465.1
ENST00000237353.10
polyamine modulated factor 1 binding protein 1
chr6_-_46922659 0.56 ENST00000265417.7
G protein-coupled receptor 116
chr10_+_51565108 0.54 ENST00000438493.1
ENST00000452682.1
nuclear receptor coactivator 4
chr1_-_23810664 0.54 ENST00000336689.3
ENST00000437606.2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr6_-_33714667 0.54 ENST00000293756.4
inositol hexakisphosphate kinase 3
chr1_-_144994840 0.54 ENST00000369351.3
ENST00000369349.3
phosphodiesterase 4D interacting protein
chr15_-_89755034 0.53 ENST00000563254.1
retinaldehyde binding protein 1
chr6_+_30539153 0.52 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ATP-binding cassette, sub-family F (GCN20), member 1
chr9_+_90112117 0.52 ENST00000358077.5
death-associated protein kinase 1
chr1_-_145076186 0.51 ENST00000369348.3
phosphodiesterase 4D interacting protein
chr4_-_120243545 0.51 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr15_-_28344439 0.50 ENST00000431101.1
ENST00000445578.1
ENST00000353809.5
ENST00000382996.2
ENST00000354638.3
oculocutaneous albinism II
chr4_+_154622652 0.50 ENST00000260010.6
toll-like receptor 2
chr4_+_86525299 0.49 ENST00000512201.1
Rho GTPase activating protein 24
chr16_-_20364030 0.49 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
uromodulin
chr9_+_18474098 0.48 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTS-like 1
chr13_+_49551020 0.48 ENST00000541916.1
fibronectin type III domain containing 3A
chr11_+_113930291 0.47 ENST00000335953.4
zinc finger and BTB domain containing 16
chr3_+_100354442 0.47 ENST00000475887.1
G protein-coupled receptor 128
chr18_-_47813940 0.47 ENST00000586837.1
ENST00000412036.2
ENST00000589940.1
CXXC finger protein 1
chr5_+_140227048 0.46 ENST00000532602.1
protocadherin alpha 9
chr21_+_38593701 0.46 ENST00000440629.1
AP001432.14
chr22_+_36113919 0.46 ENST00000249044.2
apolipoprotein L, 5
chr5_+_147258266 0.46 ENST00000296694.4
secretoglobin, family 3A, member 2
chr3_-_112218378 0.45 ENST00000334529.5
B and T lymphocyte associated
chr15_-_27018884 0.44 ENST00000299267.4
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr6_+_150690028 0.44 ENST00000229447.5
ENST00000344419.3
iodotyrosine deiodinase
chr1_-_144995002 0.44 ENST00000369356.4
phosphodiesterase 4D interacting protein
chr16_+_53133070 0.43 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr11_-_5537920 0.43 ENST00000380184.1
ubiquilin-like
chr3_+_112930387 0.43 ENST00000485230.1
BOC cell adhesion associated, oncogene regulated
chr14_+_24540046 0.43 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
copine VI (neuronal)
chr14_+_69865401 0.43 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
solute carrier family 39, member 9
chr9_-_127703333 0.42 ENST00000373555.4
golgin A1
chr12_+_133657461 0.42 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
zinc finger protein 140
chr7_-_48068699 0.41 ENST00000412142.1
ENST00000395572.2
Sad1 and UNC84 domain containing 3
chr3_+_69928256 0.41 ENST00000394355.2
microphthalmia-associated transcription factor
chr5_-_83680603 0.41 ENST00000296591.5
EGF-like repeats and discoidin I-like domains 3
chr8_-_93029865 0.40 ENST00000422361.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_-_4896205 0.40 ENST00000589389.1
glyoxylate reductase 1 homolog (Arabidopsis)
chr11_-_63376013 0.40 ENST00000540943.1
phospholipase A2, group XVI
chr13_+_77564795 0.40 ENST00000377453.3
ceroid-lipofuscinosis, neuronal 5
chr15_-_90358048 0.39 ENST00000300060.6
ENST00000560137.1
alanyl (membrane) aminopeptidase
chr7_-_48068671 0.39 ENST00000297325.4
Sad1 and UNC84 domain containing 3
chr4_-_70080449 0.38 ENST00000446444.1
UDP glucuronosyltransferase 2 family, polypeptide B11
chr10_-_28571015 0.37 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr14_-_106539557 0.37 ENST00000390599.2
immunoglobulin heavy variable 1-8
chr3_+_112930306 0.37 ENST00000495514.1
BOC cell adhesion associated, oncogene regulated
chr13_+_43355732 0.37 ENST00000313851.1
family with sequence similarity 216, member B
chr12_+_50451331 0.37 ENST00000228468.4
acid-sensing (proton-gated) ion channel 1
chr12_+_55248289 0.37 ENST00000308796.6
mucin-like 1
chr4_-_74088800 0.36 ENST00000509867.2
ankyrin repeat domain 17
chr7_-_48068643 0.36 ENST00000453192.2
Sad1 and UNC84 domain containing 3
chr10_-_48416849 0.36 ENST00000249598.1
growth differentiation factor 2
chr15_+_65843130 0.36 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr12_+_69753448 0.36 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS domain containing 4
chr4_-_89619386 0.36 ENST00000323061.5
nucleosome assembly protein 1-like 5
chr1_-_24306768 0.35 ENST00000374453.3
ENST00000453840.3
serine/arginine-rich splicing factor 10
chr16_+_28889703 0.35 ENST00000357084.3
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr11_-_44972418 0.35 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
tumor protein p53 inducible protein 11
chr3_-_148939835 0.34 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr14_-_21490653 0.34 ENST00000449431.2
NDRG family member 2
chr7_-_92463210 0.34 ENST00000265734.4
cyclin-dependent kinase 6
chr3_+_111393659 0.34 ENST00000477665.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr13_-_103719196 0.33 ENST00000245312.3
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr1_+_244214577 0.33 ENST00000358704.4
zinc finger and BTB domain containing 18
chr21_-_43786634 0.33 ENST00000291527.2
trefoil factor 1
chr5_+_147443534 0.33 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
serine peptidase inhibitor, Kazal type 5
chr3_+_113666748 0.33 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chr1_-_205091115 0.33 ENST00000264515.6
ENST00000367164.1
retinoblastoma binding protein 5
chr12_-_91546926 0.32 ENST00000550758.1
decorin
chr3_-_121379739 0.32 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr15_-_80189380 0.32 ENST00000258874.3
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr11_-_26593649 0.32 ENST00000455601.2
mucin 15, cell surface associated
chr16_+_28889801 0.31 ENST00000395503.4
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr12_+_21168630 0.31 ENST00000421593.2
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_-_45838011 0.31 ENST00000358525.4
ENST00000413781.1
solute carrier family 6 (proline IMINO transporter), member 20
chr11_-_26593677 0.31 ENST00000527569.1
mucin 15, cell surface associated
chr5_+_169931249 0.31 ENST00000520740.1
Kv channel interacting protein 1
chr4_-_153456153 0.31 ENST00000603548.1
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr16_-_20702578 0.30 ENST00000307493.4
ENST00000219151.4
acyl-CoA synthetase medium-chain family member 1
chr15_-_55700457 0.30 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr11_-_4629388 0.30 ENST00000526337.1
ENST00000300747.5
tripartite motif containing 68
chr11_-_26593779 0.30 ENST00000529533.1
mucin 15, cell surface associated
chr14_-_106926724 0.30 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr17_+_72426891 0.29 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr8_-_6783588 0.29 ENST00000297436.2
defensin, alpha 6, Paneth cell-specific
chr5_+_148737562 0.29 ENST00000274569.4
prenylcysteine oxidase 1 like
chr2_-_152830479 0.29 ENST00000360283.6
calcium channel, voltage-dependent, beta 4 subunit
chr10_-_94257512 0.29 ENST00000371581.5
insulin-degrading enzyme
chr7_-_27205136 0.29 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr7_-_80551671 0.29 ENST00000419255.2
ENST00000544525.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_-_163100045 0.29 ENST00000188790.4
fibroblast activation protein, alpha
chr17_-_6735012 0.29 ENST00000535086.1
tektin 1
chr3_-_45837959 0.29 ENST00000353278.4
ENST00000456124.2
solute carrier family 6 (proline IMINO transporter), member 20
chr14_-_21490417 0.29 ENST00000556366.1
NDRG family member 2
chr3_-_55523966 0.29 ENST00000474267.1
wingless-type MMTV integration site family, member 5A
chr5_+_43602750 0.28 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
nicotinamide nucleotide transhydrogenase
chr17_-_6735035 0.28 ENST00000338694.2
tektin 1
chr6_+_31553901 0.28 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
leukocyte specific transcript 1
chr2_-_163099885 0.27 ENST00000443424.1
fibroblast activation protein, alpha
chr10_-_97416400 0.27 ENST00000371224.2
ENST00000371221.3
aldehyde dehydrogenase 18 family, member A1
chrX_+_105412290 0.27 ENST00000357175.2
ENST00000337685.2
melanoma associated antigen (mutated) 1-like 1
chr6_-_52859046 0.27 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr1_-_198990166 0.27 ENST00000427439.1
RP11-16L9.3
chr14_-_21490958 0.27 ENST00000554104.1
NDRG family member 2
chr3_-_24207039 0.26 ENST00000280696.5
thyroid hormone receptor, beta
chr14_-_21490590 0.26 ENST00000557633.1
NDRG family member 2
chr3_-_52486841 0.26 ENST00000496590.1
troponin C type 1 (slow)
chr19_+_34972543 0.26 ENST00000590071.2
Wilms tumor 1 interacting protein
chr9_+_108424738 0.26 ENST00000334077.3
T-cell acute lymphocytic leukemia 2
chr15_+_85144217 0.26 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
zinc finger and SCAN domain containing 2
chr17_+_80214131 0.25 ENST00000598222.1
CDNA FLJ27256 fis, clone SYN09689; Uncharacterized protein
chr22_+_24999114 0.25 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
gamma-glutamyltransferase 1
chr3_-_195310802 0.25 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr2_-_80531399 0.25 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
leucine rich repeat transmembrane neuronal 1
chr17_-_39156138 0.25 ENST00000391587.1
keratin associated protein 3-2
chr11_-_59612969 0.24 ENST00000541311.1
ENST00000257248.2
gastric intrinsic factor (vitamin B synthesis)
chr16_+_24550857 0.24 ENST00000568015.1
retinoblastoma binding protein 6
chr2_+_38177575 0.24 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr7_+_107531580 0.24 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
dihydrolipoamide dehydrogenase
chr15_+_74466012 0.24 ENST00000249842.3
immunoglobulin superfamily containing leucine-rich repeat
chr18_-_59854203 0.24 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
phosphatidylinositol glycan anchor biosynthesis, class N
chr21_-_46131470 0.24 ENST00000323084.4
thrombospondin-type laminin G domain and EAR repeats
chr3_+_118905564 0.24 ENST00000460625.1
uroplakin 1B
chr22_-_36556821 0.24 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chr6_+_73076432 0.24 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr1_+_228337553 0.23 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr19_+_12035913 0.23 ENST00000591944.1
Uncharacterized protein; Zinc finger protein 763
chr13_+_111767582 0.23 ENST00000375741.2
ENST00000375739.2
Rho guanine nucleotide exchange factor (GEF) 7
chr21_-_34914394 0.23 ENST00000361093.5
ENST00000381815.4
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG3_NEUROD2_NEUROG2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.4 1.6 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.4 3.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 1.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 1.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 0.9 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 0.6 GO:0097325 melanocyte proliferation(GO:0097325)
0.3 0.8 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.3 1.3 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.3 0.8 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.2 3.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.7 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.2 0.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.2 0.7 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.5 GO:0032289 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 3.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 1.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.7 GO:0009804 coumarin metabolic process(GO:0009804)
0.1 0.6 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 1.5 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.5 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.4 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 0.5 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.3 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.6 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.3 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 1.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.3 GO:0009397 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.9 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.2 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 3.9 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 0.3 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 1.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.3 GO:0042640 anagen(GO:0042640)
0.1 0.6 GO:0015824 proline transport(GO:0015824)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.6 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.1 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 1.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.1 GO:0038185 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.2 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.8 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 2.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.2 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.7 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.3 GO:1904628 negative regulation of monocyte differentiation(GO:0045656) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.1 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 1.2 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 1.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.5 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.7 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.8 GO:0097503 sialylation(GO:0097503)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.6 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0043578 MAPK import into nucleus(GO:0000189) nuclear matrix organization(GO:0043578)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 1.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.3 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.1 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0060389 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) pathway-restricted SMAD protein phosphorylation(GO:0060389) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393) positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090100)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.0 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.4 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.0 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 3.2 GO:0005642 annulate lamellae(GO:0005642)
0.3 3.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.8 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.2 0.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 1.5 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.2 GO:0044754 autolysosome(GO:0044754)
0.1 1.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.7 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.6 GO:0033269 internode region of axon(GO:0033269)
0.1 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0036030 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 3.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3 1.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.3 1.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 3.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 0.9 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.2 0.5 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 0.8 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.2 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.9 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 2.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 1.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.5 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 2.4 GO:0070330 aromatase activity(GO:0070330)
0.1 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 3.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.9 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.1 0.6 GO:0050733 RS domain binding(GO:0050733)
0.1 0.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.3 GO:0043559 insulin binding(GO:0043559)
0.1 1.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.9 GO:0019864 IgG binding(GO:0019864)
0.1 0.2 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 1.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.7 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 3.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.5 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.5 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 1.0 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 1.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.0 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.3 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 3.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 3.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly