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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ONECUT2_ONECUT3

Z-value: 0.78

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Transcription factors associated with ONECUT2_ONECUT3

Gene Symbol Gene ID Gene Info
ONECUT2
ENSG00000119547.5 one cut homeobox 2
ONECUT3
ENSG00000205922.4 one cut homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ONECUT3hg19_v2_chr19_+_1752372_17523720.613.3e-04Click!
ONECUT2hg19_v2_chr18_+_55102917_551029850.319.9e-02Click!

Activity profile of ONECUT2_ONECUT3 motif

Sorted Z-values of ONECUT2_ONECUT3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_4385230 4.90 ENST00000536537.1
CCND2
cyclin D2
chr2_-_192016316 3.97 ENST00000358470.4
ENST00000432798.1
ENST00000450994.1
STAT4
signal transducer and activator of transcription 4
chrX_+_100805496 2.19 ENST00000372829.3
ARMCX1
armadillo repeat containing, X-linked 1
chr2_+_102413726 2.18 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr7_-_23510086 2.15 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr3_+_159557637 1.67 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr11_-_107729887 1.60 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr2_-_208030647 1.53 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr5_+_162887556 1.48 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR
hyaluronan-mediated motility receptor (RHAMM)
chr3_+_63428752 1.39 ENST00000295894.5
SYNPR
synaptoporin
chr3_+_121774202 1.31 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr8_-_117043 1.31 ENST00000320901.3
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr14_+_37126765 1.25 ENST00000402703.2
PAX9
paired box 9
chr5_+_140800638 1.17 ENST00000398587.2
ENST00000518882.1
PCDHGA11
protocadherin gamma subfamily A, 11
chr1_+_367640 1.13 ENST00000426406.1
OR4F29
olfactory receptor, family 4, subfamily F, member 29
chr5_+_180794269 1.13 ENST00000456475.1
OR4F3
olfactory receptor, family 4, subfamily F, member 3
chr7_-_143059780 1.09 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr7_-_143059845 1.08 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr4_-_70826725 1.08 ENST00000353151.3
CSN2
casein beta
chr7_+_80231466 1.07 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr20_-_1309809 1.05 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr14_-_24047965 1.03 ENST00000397118.3
ENST00000356300.4
JPH4
junctophilin 4
chr3_+_130650738 1.02 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr14_+_23012122 1.00 ENST00000390534.1
TRAJ3
T cell receptor alpha joining 3
chr7_-_28220354 0.99 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr8_+_31497271 0.94 ENST00000520407.1
NRG1
neuregulin 1
chr20_-_22566089 0.93 ENST00000377115.4
FOXA2
forkhead box A2
chr5_-_146833222 0.93 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr17_-_41623691 0.92 ENST00000545954.1
ETV4
ets variant 4
chr14_+_55034599 0.91 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr5_-_146833485 0.89 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr21_+_39628852 0.86 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_55646412 0.86 ENST00000413716.2
CCDC88A
coiled-coil domain containing 88A
chr18_+_42260861 0.85 ENST00000282030.5
SETBP1
SET binding protein 1
chr15_-_83837983 0.81 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr7_-_121944491 0.81 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr10_-_121296045 0.80 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr22_-_36220420 0.78 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_-_4535233 0.78 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr9_-_27529726 0.76 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr17_-_2304365 0.76 ENST00000575394.1
ENST00000174618.4
MNT
MAX network transcriptional repressor
chr19_+_7598890 0.74 ENST00000221249.6
ENST00000601668.1
ENST00000601001.1
PNPLA6
patatin-like phospholipase domain containing 6
chr6_+_130339710 0.74 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr1_-_26233423 0.73 ENST00000357865.2
STMN1
stathmin 1
chr9_+_77230499 0.70 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr2_+_105050794 0.69 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr1_+_99127225 0.67 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chr2_+_58655461 0.66 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr1_+_207943667 0.66 ENST00000462968.2
CD46
CD46 molecule, complement regulatory protein
chr5_+_126984710 0.65 ENST00000379445.3
CTXN3
cortexin 3
chr10_+_70980051 0.64 ENST00000354624.5
ENST00000395086.2
HKDC1
hexokinase domain containing 1
chr3_-_24207039 0.64 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chr7_+_129906660 0.63 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr17_-_41623716 0.63 ENST00000319349.5
ETV4
ets variant 4
chr12_+_9144626 0.63 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr10_+_71561704 0.62 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr11_+_8040739 0.60 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr12_-_54653313 0.59 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr19_+_7599128 0.59 ENST00000545201.2
PNPLA6
patatin-like phospholipase domain containing 6
chr3_-_141747439 0.57 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr17_-_64225508 0.55 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr11_-_102651343 0.53 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr9_-_95244781 0.52 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr20_+_36405665 0.52 ENST00000373469.1
CTNNBL1
catenin, beta like 1
chr15_+_93443419 0.50 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr11_+_18154059 0.50 ENST00000531264.1
MRGPRX3
MAS-related GPR, member X3
chrX_-_64196376 0.49 ENST00000447788.2
ZC4H2
zinc finger, C4H2 domain containing
chr3_+_63428982 0.48 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chrX_-_64196307 0.47 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr15_+_36338242 0.46 ENST00000560056.1
RP11-684B21.1
RP11-684B21.1
chr6_-_151773232 0.46 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr10_+_71561649 0.46 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chrX_-_64196351 0.45 ENST00000374839.3
ZC4H2
zinc finger, C4H2 domain containing
chr4_-_20985632 0.45 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr15_-_99789736 0.44 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr5_+_138940742 0.41 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
UBE2D2
ubiquitin-conjugating enzyme E2D 2
chr1_-_622053 0.41 ENST00000332831.2
OR4F16
olfactory receptor, family 4, subfamily F, member 16
chr19_-_52674896 0.41 ENST00000322146.8
ENST00000597065.1
ZNF836
zinc finger protein 836
chr17_-_202579 0.41 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL
rabphilin 3A-like (without C2 domains)
chr12_+_59989918 0.40 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr7_-_14026063 0.40 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr5_-_143550241 0.40 ENST00000522203.1
YIPF5
Yip1 domain family, member 5
chr10_+_71562180 0.39 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr6_+_114178512 0.39 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr10_+_133753533 0.38 ENST00000422256.2
PPP2R2D
protein phosphatase 2, regulatory subunit B, delta
chr21_+_39628655 0.38 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr4_+_71587669 0.38 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr12_+_4699244 0.38 ENST00000540757.2
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr1_+_190448095 0.38 ENST00000424735.1
RP11-547I7.2
RP11-547I7.2
chr1_-_243326612 0.37 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr2_+_241625749 0.36 ENST00000407635.2
AC011298.2
AC011298.2
chr3_-_71632894 0.33 ENST00000493089.1
FOXP1
forkhead box P1
chr2_-_163695128 0.33 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr10_-_73975657 0.33 ENST00000394919.1
ENST00000526751.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr4_+_169418255 0.33 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr19_+_45596398 0.32 ENST00000544069.2
PPP1R37
protein phosphatase 1, regulatory subunit 37
chr17_-_46691990 0.31 ENST00000576562.1
HOXB8
homeobox B8
chr16_+_72459838 0.30 ENST00000564508.1
AC004158.3
AC004158.3
chr20_-_62587735 0.30 ENST00000354216.6
ENST00000369892.3
ENST00000358711.3
UCKL1
uridine-cytidine kinase 1-like 1
chr1_+_159557607 0.30 ENST00000255040.2
APCS
amyloid P component, serum
chr5_-_9630463 0.29 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr12_-_62586543 0.28 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr14_+_93357749 0.27 ENST00000557689.1
RP11-862G15.1
RP11-862G15.1
chr1_-_894620 0.27 ENST00000327044.6
NOC2L
nucleolar complex associated 2 homolog (S. cerevisiae)
chr14_+_37131058 0.27 ENST00000361487.6
PAX9
paired box 9
chr12_+_100594557 0.26 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr4_+_174818390 0.26 ENST00000509968.1
ENST00000512263.1
RP11-161D15.1
RP11-161D15.1
chr3_+_52811596 0.26 ENST00000542827.1
ENST00000273283.2
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr10_-_98031265 0.26 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr4_+_71248795 0.26 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr19_-_44952635 0.25 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
ZNF229
zinc finger protein 229
chr3_+_188889737 0.25 ENST00000345063.3
TPRG1
tumor protein p63 regulated 1
chr4_+_187187098 0.25 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr5_-_143550159 0.24 ENST00000448443.2
ENST00000513112.1
ENST00000519064.1
ENST00000274496.5
YIPF5
Yip1 domain family, member 5
chrY_+_20137667 0.24 ENST00000250838.4
ENST00000426790.1
CDY2A
chromodomain protein, Y-linked, 2A
chrY_-_19992098 0.24 ENST00000544303.1
ENST00000382867.3
CDY2B
chromodomain protein, Y-linked, 2B
chrX_+_90689810 0.24 ENST00000312600.3
PABPC5
poly(A) binding protein, cytoplasmic 5
chr20_-_1974692 0.24 ENST00000217305.2
ENST00000539905.1
PDYN
prodynorphin
chr12_+_48866448 0.24 ENST00000266594.1
ANP32D
acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
chr8_+_70850403 0.23 ENST00000602248.1
AC090574.1
Uncharacterized protein
chr2_-_50201327 0.23 ENST00000412315.1
NRXN1
neurexin 1
chrY_+_27768264 0.23 ENST00000361963.2
ENST00000306609.4
CDY1
chromodomain protein, Y-linked, 1
chr11_-_116658758 0.23 ENST00000227322.3
ZNF259
zinc finger protein 259
chr6_+_29068386 0.22 ENST00000377171.3
OR2J1
olfactory receptor, family 2, subfamily J, member 1 (gene/pseudogene)
chr16_-_20702578 0.22 ENST00000307493.4
ENST00000219151.4
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr17_-_46692287 0.21 ENST00000239144.4
HOXB8
homeobox B8
chr2_+_67624430 0.21 ENST00000272342.5
ETAA1
Ewing tumor-associated antigen 1
chr5_-_135701164 0.21 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr3_-_187388173 0.21 ENST00000287641.3
SST
somatostatin
chr16_-_69788816 0.20 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr1_-_100598444 0.20 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr4_+_71588372 0.20 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr6_+_56954808 0.20 ENST00000510483.1
ENST00000370706.4
ENST00000357489.3
ZNF451
zinc finger protein 451
chr7_-_14026123 0.20 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr11_-_116658695 0.19 ENST00000429220.1
ENST00000444935.1
ZNF259
zinc finger protein 259
chr11_-_60623437 0.19 ENST00000332539.4
PTGDR2
prostaglandin D2 receptor 2
chr2_-_163695238 0.19 ENST00000328032.4
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr4_-_69536346 0.19 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr1_+_248201474 0.19 ENST00000366479.2
OR2L2
olfactory receptor, family 2, subfamily L, member 2
chrX_+_123480194 0.18 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr4_+_156824840 0.18 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr6_+_27925019 0.18 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr4_-_103747011 0.17 ENST00000350435.7
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_-_103746683 0.17 ENST00000504211.1
ENST00000508476.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_+_77593474 0.17 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr10_-_98031310 0.17 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr17_-_66951474 0.17 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr8_+_77593448 0.17 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr15_+_54901540 0.17 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr1_+_117297007 0.16 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr5_+_65440032 0.16 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr2_-_220174166 0.16 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr17_-_4167142 0.16 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr5_+_147774275 0.16 ENST00000513826.1
FBXO38
F-box protein 38
chr2_-_39348137 0.16 ENST00000426016.1
SOS1
son of sevenless homolog 1 (Drosophila)
chr4_-_69434245 0.15 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chrY_-_26194116 0.15 ENST00000306882.4
ENST00000382407.1
CDY1B
chromodomain protein, Y-linked, 1B
chr17_-_79876010 0.15 ENST00000328666.6
SIRT7
sirtuin 7
chr2_+_7017796 0.15 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr1_-_111150048 0.15 ENST00000485317.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr3_-_141747459 0.14 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr20_+_43849941 0.14 ENST00000372769.3
SEMG2
semenogelin II
chr4_-_103746924 0.14 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_+_169418195 0.14 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr4_+_175839551 0.14 ENST00000404450.4
ENST00000514159.1
ADAM29
ADAM metallopeptidase domain 29
chr17_-_37764128 0.14 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr14_-_23426322 0.14 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr2_+_166095898 0.13 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr14_+_88490894 0.13 ENST00000556033.1
ENST00000553929.1
ENST00000555996.1
ENST00000556673.1
ENST00000557339.1
ENST00000556684.1
RP11-300J18.3
long intergenic non-protein coding RNA 1146
chr9_-_28670283 0.12 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr14_+_22265444 0.12 ENST00000390430.2
TRAV8-1
T cell receptor alpha variable 8-1
chr14_-_23426270 0.12 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4
HAUS augmin-like complex, subunit 4
chr15_+_38226827 0.11 ENST00000559502.1
ENST00000558148.1
ENST00000558158.1
TMCO5A
transmembrane and coiled-coil domains 5A
chr1_+_207262627 0.11 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr5_-_156390230 0.11 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr14_-_23426337 0.11 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4
HAUS augmin-like complex, subunit 4
chr1_-_159684371 0.11 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
CRP
C-reactive protein, pentraxin-related
chr11_+_6947647 0.11 ENST00000278319.5
ZNF215
zinc finger protein 215
chr1_+_207262578 0.11 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr4_+_175839506 0.10 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM29
ADAM metallopeptidase domain 29
chr19_+_45596218 0.10 ENST00000421905.1
ENST00000221462.4
PPP1R37
protein phosphatase 1, regulatory subunit 37
chr3_+_46283916 0.10 ENST00000395940.2
CCR3
chemokine (C-C motif) receptor 3
chr1_-_146068184 0.10 ENST00000604894.1
ENST00000369323.3
ENST00000479926.2
NBPF11
neuroblastoma breakpoint family, member 11
chr12_+_20848282 0.10 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr12_+_20848377 0.10 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr3_-_186080012 0.09 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr1_+_207262540 0.09 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr4_-_102268484 0.09 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_115259337 0.09 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr7_+_120702819 0.09 ENST00000423795.1
CPED1
cadherin-like and PC-esterase domain containing 1
chr6_+_71122974 0.08 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr4_-_111563076 0.08 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr9_+_33629119 0.08 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chr2_+_171034646 0.08 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr16_-_2013101 0.08 ENST00000526586.2
RPS2
ribosomal protein S2
chr1_-_46664074 0.08 ENST00000371986.3
ENST00000371984.3
POMGNT1
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
chr4_+_187187337 0.07 ENST00000492972.2
F11
coagulation factor XI
chr7_+_129007964 0.07 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr1_+_144811744 0.07 ENST00000338347.4
ENST00000440491.2
ENST00000375552.4
NBPF9
neuroblastoma breakpoint family, member 9
chrX_-_19988382 0.07 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23
chromosome X open reading frame 23

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT2_ONECUT3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.4 1.1 GO:1903487 regulation of lactation(GO:1903487)
0.3 0.9 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.3 0.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.6 GO:0008050 female courtship behavior(GO:0008050)
0.2 4.9 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 1.0 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 1.1 GO:2000332 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.9 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.5 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 1.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 2.2 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.5 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 2.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.1 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.7 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.5 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 1.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.6 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 1.5 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 1.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 3.7 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 0.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 1.4 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.6 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 1.5 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.3 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.8 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0007625 grooming behavior(GO:0007625)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 2.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.3 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.6 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 2.2 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.9 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.0 GO:0090149 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.4 1.5 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.7 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 1.0 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 1.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 1.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.5 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.8 GO:0035473 lipase binding(GO:0035473)
0.1 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 2.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.9 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.9 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 2.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 1.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 5.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.3 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.2 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels