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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for OSR1_OSR2

Z-value: 0.47

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Transcription factors associated with OSR1_OSR2

Gene Symbol Gene ID Gene Info
OSR1
ENSG00000143867.5 odd-skipped related transcription factor 1
OSR2
ENSG00000164920.5 odd-skipped related transciption factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OSR2hg19_v2_chr8_+_99956759_99956887-0.251.8e-01Click!
OSR1hg19_v2_chr2_-_19558373_19558414-0.173.6e-01Click!

Activity profile of OSR1_OSR2 motif

Sorted Z-values of OSR1_OSR2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_169013666 1.46 ENST00000359299.3
ANXA10
annexin A10
chr15_-_80263506 0.93 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr7_+_134212312 0.85 ENST00000359579.4
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr7_+_76090993 0.80 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
DTX2
deltex homolog 2 (Drosophila)
chr12_-_50419177 0.79 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
RACGAP1
Rac GTPase activating protein 1
chr5_+_68463043 0.76 ENST00000508407.1
ENST00000505500.1
CCNB1
cyclin B1
chr5_+_68462944 0.63 ENST00000506572.1
CCNB1
cyclin B1
chr5_+_68462837 0.60 ENST00000256442.5
CCNB1
cyclin B1
chr1_+_159175201 0.51 ENST00000368121.2
DARC
Duffy blood group, atypical chemokine receptor
chr7_-_95225768 0.50 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr12_-_10251603 0.48 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr22_+_31489344 0.47 ENST00000404574.1
SMTN
smoothelin
chr3_-_50360192 0.46 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
HYAL2
hyaluronoglucosaminidase 2
chr12_-_10251576 0.44 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr7_-_43769066 0.41 ENST00000223336.6
ENST00000310564.6
ENST00000431651.1
ENST00000415798.1
COA1
cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
chr7_-_43769051 0.40 ENST00000395880.3
COA1
cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
chr3_+_149191723 0.39 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr9_+_36572851 0.39 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr2_+_37458928 0.38 ENST00000439218.1
ENST00000432075.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr2_+_234959323 0.33 ENST00000373368.1
ENST00000168148.3
SPP2
secreted phosphoprotein 2, 24kDa
chr15_+_63188009 0.31 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr7_+_129847688 0.31 ENST00000297819.3
SSMEM1
serine-rich single-pass membrane protein 1
chr16_+_23690138 0.30 ENST00000300093.4
PLK1
polo-like kinase 1
chr5_+_169010638 0.29 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr11_-_63439381 0.28 ENST00000538786.1
ENST00000540699.1
ATL3
atlastin GTPase 3
chr10_+_99400443 0.26 ENST00000370631.3
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr8_-_125486755 0.25 ENST00000499418.2
ENST00000530778.1
RNF139-AS1
RNF139 antisense RNA 1 (head to head)
chr21_-_31859755 0.25 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr22_-_26986045 0.25 ENST00000442495.1
ENST00000440953.1
ENST00000450022.1
ENST00000338754.4
TPST2
tyrosylprotein sulfotransferase 2
chr17_+_79859985 0.25 ENST00000333383.7
NPB
neuropeptide B
chr11_+_65407331 0.25 ENST00000527525.1
SIPA1
signal-induced proliferation-associated 1
chr11_+_64808675 0.24 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr2_+_234959376 0.24 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr2_+_44589036 0.23 ENST00000402247.1
ENST00000407131.1
ENST00000403853.3
ENST00000378494.3
CAMKMT
calmodulin-lysine N-methyltransferase
chr11_+_62648336 0.23 ENST00000338663.7
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr9_+_103189660 0.23 ENST00000374886.3
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr19_-_41220957 0.22 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
ADCK4
aarF domain containing kinase 4
chr1_+_218458625 0.22 ENST00000366932.3
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr12_-_123187890 0.22 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr10_+_78078088 0.22 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr1_+_232940643 0.22 ENST00000418460.1
MAP10
microtubule-associated protein 10
chr5_-_125930929 0.21 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr4_+_39460689 0.21 ENST00000381846.1
LIAS
lipoic acid synthetase
chr11_-_82997420 0.21 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr19_-_52391142 0.21 ENST00000446514.1
ENST00000458390.1
ENST00000420592.1
ENST00000451628.2
ENST00000592321.1
ENST00000591320.1
ENST00000412216.1
ENST00000301399.5
ZNF577
zinc finger protein 577
chr3_+_40428647 0.20 ENST00000301825.3
ENST00000439533.1
ENST00000456402.1
ENTPD3
ectonucleoside triphosphate diphosphohydrolase 3
chr5_-_147211226 0.20 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr12_-_123201337 0.20 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr2_+_37458776 0.19 ENST00000002125.4
ENST00000336237.6
ENST00000431821.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr1_+_97187318 0.17 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr5_+_145826867 0.17 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr1_-_179112173 0.17 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr15_+_41523417 0.17 ENST00000560397.1
CHP1
calcineurin-like EF-hand protein 1
chr17_+_60758814 0.16 ENST00000579432.1
ENST00000446119.2
MRC2
mannose receptor, C type 2
chr13_-_103389159 0.16 ENST00000322527.2
CCDC168
coiled-coil domain containing 168
chr7_+_123565286 0.16 ENST00000402183.2
ENST00000413927.1
ENST00000460182.1
ENST00000340011.5
SPAM1
sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
chrX_-_134049233 0.16 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr4_+_39460659 0.15 ENST00000513731.1
LIAS
lipoic acid synthetase
chr14_-_107083690 0.15 ENST00000455737.1
ENST00000390629.2
IGHV4-59
immunoglobulin heavy variable 4-59
chr16_-_56701933 0.15 ENST00000568675.1
ENST00000569500.1
ENST00000444837.2
ENST00000379811.3
MT1G
metallothionein 1G
chr1_+_196857144 0.15 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr2_-_32490801 0.14 ENST00000360906.5
ENST00000342905.6
NLRC4
NLR family, CARD domain containing 4
chr1_-_207143802 0.14 ENST00000324852.4
ENST00000400962.3
FCAMR
Fc receptor, IgA, IgM, high affinity
chr7_+_63361201 0.14 ENST00000450544.1
RP11-340I6.8
RP11-340I6.8
chr5_+_36152091 0.14 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr12_-_101604185 0.14 ENST00000536262.2
SLC5A8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr2_-_32490859 0.13 ENST00000404025.2
NLRC4
NLR family, CARD domain containing 4
chr4_+_145567173 0.13 ENST00000296575.3
HHIP
hedgehog interacting protein
chr22_+_37309662 0.13 ENST00000403662.3
ENST00000262825.5
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr12_-_86650045 0.13 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_-_122791583 0.12 ENST00000506636.1
ENST00000264499.4
BBS7
Bardet-Biedl syndrome 7
chr8_-_120605194 0.12 ENST00000522167.1
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_-_36812323 0.12 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr2_+_178257372 0.12 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr3_+_45927994 0.12 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chrY_-_6742068 0.11 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr19_-_9903666 0.11 ENST00000592587.1
ZNF846
zinc finger protein 846
chr5_+_36152163 0.11 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_-_48390973 0.11 ENST00000224600.4
RBP3
retinol binding protein 3, interstitial
chr19_-_17185848 0.11 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chr8_+_26247878 0.11 ENST00000518611.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr19_+_7459998 0.11 ENST00000319670.9
ENST00000599752.1
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr5_+_70220768 0.11 ENST00000351205.4
ENST00000503079.2
ENST00000380707.4
ENST00000514951.1
ENST00000506163.1
SMN1
survival of motor neuron 1, telomeric
chr2_-_74007193 0.11 ENST00000377706.4
ENST00000443070.1
ENST00000272444.3
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr1_-_71546690 0.10 ENST00000254821.6
ZRANB2
zinc finger, RAN-binding domain containing 2
chr5_-_132166579 0.10 ENST00000378679.3
SHROOM1
shroom family member 1
chr3_+_101504200 0.10 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr2_-_105030466 0.10 ENST00000449772.1
AC068535.3
AC068535.3
chr2_-_183387064 0.10 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr9_+_112542591 0.10 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr7_-_135412925 0.10 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr4_+_145567297 0.10 ENST00000434550.2
HHIP
hedgehog interacting protein
chr2_-_37458749 0.09 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr5_+_69345350 0.09 ENST00000380741.4
ENST00000380743.4
ENST00000511812.1
ENST00000380742.4
SMN2
survival of motor neuron 2, centromeric
chr17_-_79894651 0.09 ENST00000584848.1
ENST00000577756.1
ENST00000329875.8
PYCR1
pyrroline-5-carboxylate reductase 1
chr4_+_128554081 0.09 ENST00000335251.6
ENST00000296461.5
INTU
inturned planar cell polarity protein
chr19_-_13068012 0.09 ENST00000316939.1
GADD45GIP1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr14_-_39417410 0.09 ENST00000557019.1
ENST00000556116.1
ENST00000554732.1
LINC00639
long intergenic non-protein coding RNA 639
chr1_+_196743943 0.09 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr3_-_186080012 0.09 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr22_-_42336209 0.09 ENST00000472374.2
CENPM
centromere protein M
chr16_+_89696692 0.08 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr9_-_132586378 0.08 ENST00000351698.4
TOR1A
torsin family 1, member A (torsin A)
chr14_-_39417473 0.08 ENST00000553932.1
LINC00639
long intergenic non-protein coding RNA 639
chr7_-_144533074 0.08 ENST00000360057.3
ENST00000378099.3
TPK1
thiamin pyrophosphokinase 1
chr2_-_44588893 0.08 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
PREPL
prolyl endopeptidase-like
chr17_+_36284791 0.08 ENST00000505415.1
TBC1D3F
TBC1 domain family, member 3F
chr12_+_58166370 0.07 ENST00000300209.8
METTL21B
methyltransferase like 21B
chr8_+_125486939 0.07 ENST00000303545.3
RNF139
ring finger protein 139
chr1_-_231560790 0.07 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr15_-_66649010 0.07 ENST00000367709.4
ENST00000261881.4
TIPIN
TIMELESS interacting protein
chr1_+_196743912 0.07 ENST00000367425.4
CFHR3
complement factor H-related 3
chr7_+_112090483 0.07 ENST00000403825.3
ENST00000429071.1
IFRD1
interferon-related developmental regulator 1
chr8_+_20054878 0.07 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr9_-_34710066 0.07 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chr17_-_34756219 0.07 ENST00000451448.2
ENST00000394359.3
TBC1D3C
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3H
chr3_+_140947563 0.07 ENST00000505013.1
ACPL2
acid phosphatase-like 2
chr10_-_43904235 0.07 ENST00000356053.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_+_99729813 0.07 ENST00000457765.1
LPPR4
Lipid phosphate phosphatase-related protein type 4
chr13_-_52980263 0.07 ENST00000258613.4
ENST00000544466.1
THSD1
thrombospondin, type I, domain containing 1
chr11_-_35287243 0.07 ENST00000464522.2
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr4_+_151503077 0.06 ENST00000317605.4
MAB21L2
mab-21-like 2 (C. elegans)
chr12_+_27396901 0.06 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr12_+_109273806 0.06 ENST00000228476.3
ENST00000547768.1
DAO
D-amino-acid oxidase
chr1_+_40505891 0.06 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr12_+_58166431 0.06 ENST00000333012.5
METTL21B
methyltransferase like 21B
chr21_+_43919710 0.06 ENST00000398341.3
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr17_-_79895097 0.06 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr19_-_7694417 0.06 ENST00000358368.4
ENST00000534844.1
XAB2
XPA binding protein 2
chr18_+_616672 0.06 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr9_-_95056010 0.06 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr10_+_102882536 0.05 ENST00000598040.1
HUG1
HUG1
chrX_-_134049262 0.05 ENST00000370783.3
MOSPD1
motile sperm domain containing 1
chr9_-_95055956 0.05 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr10_-_43904608 0.05 ENST00000337970.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chrX_-_15333736 0.05 ENST00000380470.3
ASB11
ankyrin repeat and SOCS box containing 11
chr18_+_63418068 0.05 ENST00000397968.2
CDH7
cadherin 7, type 2
chr11_-_63439174 0.05 ENST00000332645.4
ATL3
atlastin GTPase 3
chr1_-_167487758 0.05 ENST00000362089.5
CD247
CD247 molecule
chr2_+_70056762 0.04 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr17_-_79895154 0.04 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chrX_+_11776278 0.04 ENST00000312196.4
ENST00000337339.2
MSL3
male-specific lethal 3 homolog (Drosophila)
chr1_-_25291475 0.04 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chrX_-_15333775 0.04 ENST00000480796.1
ASB11
ankyrin repeat and SOCS box containing 11
chr1_+_42922173 0.04 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS
phosphopantothenoylcysteine synthetase
chr20_-_1472029 0.04 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr6_+_10585979 0.04 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr4_-_8430152 0.04 ENST00000514423.1
ENST00000503233.1
ACOX3
acyl-CoA oxidase 3, pristanoyl
chr2_-_201828356 0.04 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr16_-_68033356 0.04 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
DPEP2
dipeptidase 2
chr12_-_86650077 0.04 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_-_14967095 0.04 ENST00000316048.2
SMCO3
single-pass membrane protein with coiled-coil domains 3
chr11_-_63439013 0.04 ENST00000398868.3
ATL3
atlastin GTPase 3
chr12_+_94656297 0.03 ENST00000545312.1
PLXNC1
plexin C1
chr1_-_237167718 0.03 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr2_-_74735707 0.03 ENST00000233630.6
PCGF1
polycomb group ring finger 1
chr8_+_96037255 0.03 ENST00000286687.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chrX_+_113818545 0.03 ENST00000371951.1
ENST00000276198.1
ENST00000371950.3
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
chr1_+_10003486 0.03 ENST00000403197.1
ENST00000377205.1
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr1_+_239882842 0.03 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr2_+_217277466 0.03 ENST00000358207.5
ENST00000434435.1
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr2_-_44588679 0.03 ENST00000409411.1
PREPL
prolyl endopeptidase-like
chr2_-_44588694 0.03 ENST00000409957.1
PREPL
prolyl endopeptidase-like
chr18_+_616711 0.03 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr2_-_44588624 0.03 ENST00000438314.1
ENST00000409936.1
PREPL
prolyl endopeptidase-like
chr17_+_40714092 0.03 ENST00000420359.1
ENST00000449624.1
ENST00000585811.1
ENST00000585909.1
ENST00000586771.1
ENST00000421097.2
ENST00000591779.1
ENST00000587858.1
ENST00000587214.1
ENST00000587157.1
ENST00000590958.1
ENST00000393818.2
COASY
CoA synthase
chr19_+_19303008 0.03 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr3_+_156799587 0.03 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr4_+_36283213 0.03 ENST00000357504.3
DTHD1
death domain containing 1
chr3_+_40498783 0.03 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
RPL14
ribosomal protein L14
chr15_+_79603404 0.03 ENST00000299705.5
TMED3
transmembrane emp24 protein transport domain containing 3
chr15_+_36994210 0.02 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr13_-_108867846 0.02 ENST00000442234.1
LIG4
ligase IV, DNA, ATP-dependent
chr6_+_3982909 0.02 ENST00000356722.3
C6ORF50
C6ORF50
chr5_+_135468516 0.02 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr4_-_70361615 0.02 ENST00000305107.6
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr20_-_30311703 0.02 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2L1
BCL2-like 1
chr4_-_113437328 0.02 ENST00000313341.3
NEUROG2
neurogenin 2
chr15_+_66161802 0.02 ENST00000566233.1
ENST00000565075.1
ENST00000435304.2
RAB11A
RAB11A, member RAS oncogene family
chr7_-_6312206 0.02 ENST00000350796.3
CYTH3
cytohesin 3
chr2_+_79412357 0.02 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr22_+_32870661 0.02 ENST00000266087.7
FBXO7
F-box protein 7
chr6_+_152011628 0.02 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr15_+_66161871 0.02 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr4_-_70361579 0.01 ENST00000512583.1
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr19_+_39989580 0.01 ENST00000596614.1
ENST00000205143.4
DLL3
delta-like 3 (Drosophila)
chr15_+_66161792 0.01 ENST00000564910.1
ENST00000261890.2
RAB11A
RAB11A, member RAS oncogene family
chr19_+_39989535 0.01 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr14_-_93651186 0.01 ENST00000556883.1
ENST00000298894.4
MOAP1
modulator of apoptosis 1
chr1_-_10003372 0.01 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
LZIC
leucine zipper and CTNNBIP1 domain containing
chr20_+_10415931 0.01 ENST00000334534.5
SLX4IP
SLX4 interacting protein
chr6_-_136788001 0.01 ENST00000544465.1
MAP7
microtubule-associated protein 7
chrY_+_3447082 0.01 ENST00000321217.4
ENST00000559055.2
TGIF2LY
TGFB-induced factor homeobox 2-like, Y-linked
chr16_-_66968055 0.01 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr19_+_55591743 0.01 ENST00000588359.1
ENST00000245618.5
EPS8L1
EPS8-like 1
chr5_-_140053152 0.01 ENST00000542735.1
DND1
DND microRNA-mediated repression inhibitor 1
chr10_-_111683308 0.01 ENST00000502935.1
ENST00000322238.8
ENST00000369680.4
XPNPEP1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr11_-_5173599 0.01 ENST00000328942.1
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr8_-_57906362 0.01 ENST00000262644.4
IMPAD1
inositol monophosphatase domain containing 1
chr12_-_95467356 0.01 ENST00000393101.3
ENST00000333003.5
NR2C1
nuclear receptor subfamily 2, group C, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0046680 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.2 0.9 GO:0016095 polyprenol catabolic process(GO:0016095)
0.2 0.8 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 0.5 GO:0019087 transformation of host cell by virus(GO:0019087)
0.1 0.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.3 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.2 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.3 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.8 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.1 GO:0033121 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.0 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.3 GO:0035838 growing cell tip(GO:0035838)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.9 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.5 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.1 0.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.3 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 1.0 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane