Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for OTX1

Z-value: 0.75

Motif logo

logo of

Transcription factors associated with OTX1

Gene Symbol Gene ID Gene Info
OTX1
ENSG00000115507.5 orthodenticle homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OTX1hg19_v2_chr2_+_63277927_632779380.579.3e-04Click!

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_65769392 5.24 ENST00000555736.1
CTD-2509G16.5
CTD-2509G16.5
chr19_-_55677999 4.44 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3
dynein, axonemal, assembly factor 3
chr19_-_55677920 4.32 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr17_-_4689649 3.25 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr12_-_71533055 3.19 ENST00000552128.1
TSPAN8
tetraspanin 8
chr2_-_160654745 2.68 ENST00000259053.4
ENST00000429078.2
CD302
CD302 molecule
chr12_+_20963647 2.49 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr12_+_20963632 2.44 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_-_146696901 2.40 ENST00000369272.3
ENST00000441068.2
FMO5
flavin containing monooxygenase 5
chr2_+_102721023 2.10 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr9_-_35563896 2.00 ENST00000399742.2
FAM166B
family with sequence similarity 166, member B
chr3_+_58223228 1.87 ENST00000478253.1
ENST00000295962.4
ABHD6
abhydrolase domain containing 6
chr3_+_111393659 1.84 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr17_-_34329084 1.79 ENST00000354059.4
ENST00000536149.1
CCL15
CCL14
chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chr3_+_42544084 1.75 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
VIPR1
vasoactive intestinal peptide receptor 1
chr10_+_114133773 1.71 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_+_41158742 1.53 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr10_-_104211294 1.52 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95
chr8_-_133637624 1.51 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr1_-_92351769 1.38 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr2_+_170335924 1.37 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
BBS5
RP11-724O16.1
Bardet-Biedl syndrome 5
Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr14_-_89878369 1.36 ENST00000553840.1
ENST00000556916.1
FOXN3
forkhead box N3
chr6_-_9939552 1.18 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr3_-_193272874 1.14 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr7_-_120498357 1.08 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr3_-_193272741 1.05 ENST00000392443.3
ATP13A4
ATPase type 13A4
chr10_-_50122277 1.04 ENST00000374160.3
LRRC18
leucine rich repeat containing 18
chr20_+_48884002 1.02 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr15_-_55657428 1.00 ENST00000568543.1
CCPG1
cell cycle progression 1
chr12_-_107380910 0.97 ENST00000392830.2
ENST00000240050.4
MTERFD3
MTERF domain containing 3
chr1_+_170501270 0.96 ENST00000367763.3
ENST00000367762.1
GORAB
golgin, RAB6-interacting
chr14_-_24911448 0.95 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr15_-_43876702 0.94 ENST00000348806.6
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr1_+_63989004 0.93 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr22_+_39052632 0.93 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr15_-_43877062 0.91 ENST00000381885.1
ENST00000396923.3
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr2_+_109403193 0.89 ENST00000412964.2
ENST00000295124.4
CCDC138
coiled-coil domain containing 138
chr12_-_107380846 0.88 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERFD3
MTERF domain containing 3
chr1_-_247335269 0.88 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
ZNF124
zinc finger protein 124
chr12_+_108523133 0.83 ENST00000547525.1
WSCD2
WSC domain containing 2
chr19_-_47616992 0.83 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr1_+_174844645 0.82 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr1_+_40840320 0.80 ENST00000372708.1
SMAP2
small ArfGAP2
chr1_-_154928562 0.80 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr1_+_196621002 0.80 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr19_+_35940486 0.79 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr3_-_27410847 0.74 ENST00000429845.2
ENST00000341435.5
ENST00000435750.1
NEK10
NIMA-related kinase 10
chr21_+_44073916 0.72 ENST00000349112.3
ENST00000398224.3
PDE9A
phosphodiesterase 9A
chr14_-_102706934 0.71 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
MOK
MOK protein kinase
chr17_-_56769382 0.69 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
TEX14
testis expressed 14
chr5_-_111091948 0.69 ENST00000447165.2
NREP
neuronal regeneration related protein
chr3_+_138340049 0.69 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr15_-_61521495 0.68 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr3_+_195447738 0.68 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr12_+_124997766 0.67 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr8_-_10512569 0.63 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr2_+_204103663 0.62 ENST00000356079.4
ENST00000429815.2
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chrX_-_100307043 0.60 ENST00000372939.1
ENST00000372935.1
ENST00000372936.3
TRMT2B
tRNA methyltransferase 2 homolog B (S. cerevisiae)
chr2_+_201936458 0.59 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr16_-_8962200 0.57 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr19_+_21265028 0.57 ENST00000291770.7
ZNF714
zinc finger protein 714
chr4_+_189060573 0.56 ENST00000332517.3
TRIML1
tripartite motif family-like 1
chr20_-_3140490 0.56 ENST00000449731.1
ENST00000380266.3
UBOX5
FASTKD5
U-box domain containing 5
FAST kinase domains 5
chr16_+_14802801 0.56 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr1_+_172502336 0.53 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chr8_-_33370607 0.52 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr3_+_138340067 0.52 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr3_+_142315225 0.52 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr22_+_30163340 0.50 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr11_-_67275542 0.48 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr1_+_229440129 0.46 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr12_-_54071181 0.46 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr11_+_113258495 0.45 ENST00000303941.3
ANKK1
ankyrin repeat and kinase domain containing 1
chr10_-_28571015 0.45 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_-_234475380 0.45 ENST00000443711.2
ENST00000251722.6
USP40
ubiquitin specific peptidase 40
chr19_+_10531150 0.44 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_-_62420757 0.44 ENST00000330574.2
INTS5
integrator complex subunit 5
chrM_+_12331 0.43 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr14_-_102552659 0.43 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr1_+_18434240 0.43 ENST00000251296.1
IGSF21
immunoglobin superfamily, member 21
chr22_-_30162924 0.41 ENST00000344318.3
ENST00000397781.3
ZMAT5
zinc finger, matrin-type 5
chr3_+_192958914 0.41 ENST00000264735.2
ENST00000602513.1
HRASLS
HRAS-like suppressor
chr3_-_58572760 0.41 ENST00000447756.2
FAM107A
family with sequence similarity 107, member A
chr8_-_79717750 0.41 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr11_-_130786333 0.40 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19
sorting nexin 19
chr7_-_91509986 0.39 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF
mitochondrial transcription termination factor
chr8_-_145652336 0.39 ENST00000529182.1
ENST00000526054.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr9_-_113100088 0.39 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr16_-_58163299 0.39 ENST00000262498.3
C16orf80
chromosome 16 open reading frame 80
chr14_+_50234309 0.38 ENST00000298307.5
KLHDC2
kelch domain containing 2
chr21_-_43816052 0.38 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr1_-_16539094 0.37 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr8_+_132916318 0.36 ENST00000254624.5
ENST00000522709.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr4_+_159727272 0.35 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr4_-_54424366 0.34 ENST00000306888.2
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr8_+_109455845 0.34 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr6_+_140175987 0.33 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr9_+_116172958 0.32 ENST00000374165.1
C9orf43
chromosome 9 open reading frame 43
chr14_-_27066960 0.32 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chr1_+_45805342 0.32 ENST00000372090.5
TOE1
target of EGR1, member 1 (nuclear)
chr7_+_99195878 0.30 ENST00000453227.1
ENST00000429679.1
GS1-259H13.2
GS1-259H13.2
chr15_+_75550940 0.30 ENST00000300576.5
GOLGA6C
golgin A6 family, member C
chr7_+_99195677 0.30 ENST00000431679.1
GS1-259H13.2
GS1-259H13.2
chr5_+_101569696 0.30 ENST00000597120.1
AC008948.1
AC008948.1
chr5_+_177631497 0.29 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr5_+_134303591 0.29 ENST00000282611.6
CATSPER3
cation channel, sperm associated 3
chr6_+_38690622 0.28 ENST00000327475.6
DNAH8
dynein, axonemal, heavy chain 8
chr3_-_12587055 0.28 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr12_+_7864021 0.28 ENST00000345088.2
DPPA3
developmental pluripotency associated 3
chr16_-_29874462 0.28 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr19_-_41903161 0.28 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr19_+_17448348 0.28 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
GTPBP3
GTP binding protein 3 (mitochondrial)
chr6_-_137539651 0.27 ENST00000543628.1
IFNGR1
interferon gamma receptor 1
chr13_-_31736478 0.27 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr12_+_49740700 0.27 ENST00000549441.2
ENST00000395069.3
DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chrX_+_1734051 0.27 ENST00000381229.4
ENST00000381233.3
ASMT
acetylserotonin O-methyltransferase
chr16_-_21436459 0.27 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr5_-_59783882 0.26 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_+_1733876 0.26 ENST00000381241.3
ASMT
acetylserotonin O-methyltransferase
chr1_-_151300160 0.24 ENST00000368874.4
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr11_+_55944094 0.24 ENST00000312298.1
OR5J2
olfactory receptor, family 5, subfamily J, member 2
chr2_-_96192450 0.24 ENST00000609975.1
RP11-440D17.3
RP11-440D17.3
chr12_-_14956396 0.23 ENST00000535328.1
ENST00000261167.2
WBP11
WW domain binding protein 11
chr5_+_140079919 0.23 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr10_+_24755416 0.23 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr3_-_141747950 0.22 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_24882560 0.21 ENST00000374392.2
NCMAP
noncompact myelin associated protein
chr1_+_150293973 0.21 ENST00000414970.2
ENST00000543398.1
PRPF3
pre-mRNA processing factor 3
chr3_-_69129501 0.21 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr16_-_66583701 0.20 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2
thymidine kinase 2, mitochondrial
chr20_+_3052264 0.20 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr10_+_60028818 0.20 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr1_+_81771806 0.19 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr2_+_201936707 0.19 ENST00000433898.1
ENST00000454214.1
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr12_-_117537240 0.19 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
TESC
tescalcin
chrX_-_43832711 0.19 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr1_+_150293921 0.19 ENST00000324862.6
PRPF3
pre-mRNA processing factor 3
chr6_+_132873832 0.19 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr20_-_33539655 0.19 ENST00000451957.2
GSS
glutathione synthetase
chr10_+_52724028 0.18 ENST00000561565.1
RP11-96B5.4
RP11-96B5.4
chr2_-_161350305 0.18 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_-_8770956 0.18 ENST00000311434.9
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr6_-_32731243 0.17 ENST00000427449.1
ENST00000411527.1
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr11_-_111957451 0.17 ENST00000504148.2
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr7_-_100895414 0.16 ENST00000435848.1
ENST00000474120.1
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr22_-_36903101 0.15 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr4_+_100737954 0.15 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr13_+_23755099 0.14 ENST00000537476.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr1_-_160832642 0.14 ENST00000368034.4
CD244
CD244 molecule, natural killer cell receptor 2B4
chr10_-_35104185 0.14 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr1_+_40723779 0.14 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr3_-_156878540 0.14 ENST00000461804.1
CCNL1
cyclin L1
chr5_-_154230130 0.14 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr2_+_122513109 0.13 ENST00000389682.3
ENST00000536142.1
TSN
translin
chr11_+_130029457 0.13 ENST00000278742.5
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr16_-_21868978 0.13 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4
nuclear pore complex interacting protein family, member B4
chr9_-_100935043 0.13 ENST00000343933.5
CORO2A
coronin, actin binding protein, 2A
chr7_+_55980331 0.13 ENST00000429591.2
ZNF713
zinc finger protein 713
chr5_-_54603368 0.13 ENST00000508346.1
ENST00000251636.5
DHX29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr8_-_56986768 0.13 ENST00000523936.1
RPS20
ribosomal protein S20
chrX_+_53123314 0.12 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5
long intergenic non-protein coding RNA 1155
chr2_-_201936302 0.12 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr1_-_205719295 0.12 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr2_-_112642267 0.11 ENST00000341068.3
ANAPC1
anaphase promoting complex subunit 1
chrX_+_149861836 0.11 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
MTMR1
myotubularin related protein 1
chr3_+_136649311 0.11 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr15_+_42787452 0.10 ENST00000249647.3
SNAP23
synaptosomal-associated protein, 23kDa
chr2_+_1418154 0.10 ENST00000423320.1
ENST00000382198.1
TPO
thyroid peroxidase
chr8_+_101162812 0.09 ENST00000353107.3
ENST00000522439.1
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr21_+_18811205 0.09 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr6_-_41039567 0.09 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr7_-_100239132 0.09 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr16_-_29415350 0.08 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr16_-_69373396 0.07 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr17_-_26876350 0.07 ENST00000470125.1
UNC119
unc-119 homolog (C. elegans)
chrX_+_76709648 0.07 ENST00000439435.1
FGF16
fibroblast growth factor 16
chr1_+_117910047 0.07 ENST00000356554.3
MAN1A2
mannosidase, alpha, class 1A, member 2
chr9_-_116172946 0.06 ENST00000374171.4
POLE3
polymerase (DNA directed), epsilon 3, accessory subunit
chr6_-_133055815 0.06 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr5_-_147286065 0.06 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr14_+_21458127 0.04 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
METTL17
methyltransferase like 17
chrX_+_133507283 0.03 ENST00000370803.3
PHF6
PHD finger protein 6
chr7_+_120702819 0.03 ENST00000423795.1
CPED1
cadherin-like and PC-esterase domain containing 1
chr2_+_16080659 0.03 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr11_-_40315640 0.02 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr4_+_83956237 0.02 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr5_+_135496675 0.02 ENST00000507637.1
SMAD5
SMAD family member 5
chr2_-_111230393 0.02 ENST00000447537.2
ENST00000413601.2
LIMS3L
LIMS3L
LIM and senescent cell antigen-like-containing domain protein 3; Uncharacterized protein; cDNA FLJ59124, highly similar to Particularly interesting newCys-His protein; cDNA, FLJ79109, highly similar to Particularly interesting newCys-His protein
LIM and senescent cell antigen-like domains 3-like
chr1_+_241695424 0.01 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr18_+_8717369 0.01 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA2
SOGA family member 2
chr1_-_9811600 0.01 ENST00000435891.1
CLSTN1
calsyntenin 1
chrX_+_11311533 0.00 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
AMELX
amelogenin, X-linked
chr6_+_96025341 0.00 ENST00000369293.1
ENST00000358812.4
MANEA
mannosidase, endo-alpha
chr17_-_39324424 0.00 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr3_-_69062764 0.00 ENST00000295571.5
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.4 11.6 GO:0044458 motile cilium assembly(GO:0044458)
0.3 1.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 1.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 0.8 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 1.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.5 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.4 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 1.8 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 0.5 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.4 GO:1990502 dense core granule maturation(GO:1990502)
0.1 4.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.2 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.3 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.7 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.1 1.0 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.1 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 1.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 1.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.2 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.7 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.8 GO:0016180 snRNA processing(GO:0016180)
0.0 3.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.6 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 1.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.7 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.5 GO:0006468 protein phosphorylation(GO:0006468)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:0016579 protein deubiquitination(GO:0016579)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.4 GO:0034464 BBSome(GO:0034464)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.0 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.7 GO:1902911 protein kinase complex(GO:1902911)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 3.4 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.6 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 4.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4 1.8 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 1.7 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.3 2.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 4.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.1 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.8 ST ADRENERGIC Adrenergic Pathway
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 2.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling