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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for OTX2_CRX

Z-value: 0.67

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Transcription factors associated with OTX2_CRX

Gene Symbol Gene ID Gene Info
OTX2
ENSG00000165588.12 orthodenticle homeobox 2
CRX
ENSG00000105392.11 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OTX2hg19_v2_chr14_-_57277178_572772030.667.5e-05Click!
CRXhg19_v2_chr19_+_48325097_483252110.412.3e-02Click!

Activity profile of OTX2_CRX motif

Sorted Z-values of OTX2_CRX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_38859996 9.62 ENST00000264651.2
KRT24
keratin 24
chr8_+_54764346 3.83 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr15_-_74495188 2.63 ENST00000563965.1
ENST00000395105.4
STRA6
stimulated by retinoic acid 6
chr19_-_51538118 2.49 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr19_-_51538148 2.47 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr6_+_130339710 2.14 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr3_-_149095652 1.80 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr9_+_75229616 1.76 ENST00000340019.3
TMC1
transmembrane channel-like 1
chrX_+_69488174 1.72 ENST00000480877.2
ENST00000307959.8
ARR3
arrestin 3, retinal (X-arrestin)
chr5_-_149669192 1.66 ENST00000398376.3
CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr9_+_116298778 1.53 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr8_-_91095099 1.44 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr16_+_58010339 1.40 ENST00000290871.5
ENST00000441824.2
TEPP
testis, prostate and placenta expressed
chr2_+_219472488 1.39 ENST00000450993.2
PLCD4
phospholipase C, delta 4
chr18_-_28681950 1.34 ENST00000251081.6
DSC2
desmocollin 2
chr1_+_180897269 1.32 ENST00000367587.1
KIAA1614
KIAA1614
chrX_+_69488155 1.28 ENST00000374495.3
ARR3
arrestin 3, retinal (X-arrestin)
chr19_+_46001697 1.18 ENST00000451287.2
ENST00000324688.4
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chrX_+_69509927 1.18 ENST00000374403.3
KIF4A
kinesin family member 4A
chr15_+_33603147 1.09 ENST00000415757.3
ENST00000389232.4
RYR3
ryanodine receptor 3
chr18_-_64271316 1.08 ENST00000540086.1
ENST00000580157.1
CDH19
cadherin 19, type 2
chr12_-_2027639 1.04 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr11_-_62752162 1.01 ENST00000458333.2
ENST00000421062.2
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr6_-_35480640 1.00 ENST00000428978.1
ENST00000322263.4
TULP1
tubby like protein 1
chr18_-_28682374 0.96 ENST00000280904.6
DSC2
desmocollin 2
chr9_-_39288092 0.94 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3
contactin associated protein-like 3
chr12_+_53693466 0.91 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr1_-_150208320 0.85 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_+_53693812 0.82 ENST00000549488.1
C12orf10
chromosome 12 open reading frame 10
chr1_+_55505184 0.81 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chr10_-_105845674 0.79 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr1_+_11751748 0.78 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein
chr3_+_111393501 0.78 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr8_+_70378852 0.75 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chr15_-_34610962 0.74 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr12_-_53189892 0.73 ENST00000309505.3
ENST00000417996.2
KRT3
keratin 3
chr16_-_58004992 0.72 ENST00000564448.1
ENST00000251102.8
ENST00000311183.4
CNGB1
cyclic nucleotide gated channel beta 1
chr12_-_53171128 0.72 ENST00000332411.2
KRT76
keratin 76
chrX_+_135279179 0.72 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr19_-_51537982 0.70 ENST00000525263.1
KLK12
kallikrein-related peptidase 12
chr11_+_20044096 0.67 ENST00000533917.1
NAV2
neuron navigator 2
chr11_+_124735282 0.65 ENST00000397801.1
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr6_+_34433844 0.64 ENST00000244458.2
ENST00000374043.2
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr6_+_35310312 0.62 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr3_-_54962100 0.62 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr17_-_43209862 0.62 ENST00000322765.5
PLCD3
phospholipase C, delta 3
chr12_+_7941989 0.61 ENST00000229307.4
NANOG
Nanog homeobox
chr19_+_48325097 0.60 ENST00000221996.7
ENST00000539067.1
CRX
cone-rod homeobox
chr17_-_60885659 0.60 ENST00000311269.5
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chrX_+_41306575 0.60 ENST00000342595.2
ENST00000378220.1
NYX
nyctalopin
chr17_-_60885700 0.59 ENST00000583600.1
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chrX_+_135278908 0.58 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr6_-_66417107 0.57 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr6_+_35310391 0.57 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
PPARD
peroxisome proliferator-activated receptor delta
chr7_-_83824169 0.56 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr9_+_18474204 0.55 ENST00000276935.6
ADAMTSL1
ADAMTS-like 1
chr7_+_93535817 0.54 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr13_-_36050819 0.54 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr3_+_130650738 0.54 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr10_-_86001210 0.54 ENST00000372105.3
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr20_+_42984330 0.54 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr12_-_54779511 0.51 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr3_-_47950745 0.51 ENST00000429422.1
MAP4
microtubule-associated protein 4
chrX_-_124097620 0.50 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr9_+_34179003 0.50 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
UBAP1
ubiquitin associated protein 1
chr10_-_48390973 0.50 ENST00000224600.4
RBP3
retinol binding protein 3, interstitial
chr5_-_95768973 0.50 ENST00000311106.3
PCSK1
proprotein convertase subtilisin/kexin type 1
chr11_-_8680383 0.49 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr3_-_48229846 0.49 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr1_-_231560790 0.48 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr1_+_159409512 0.48 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr14_-_95236551 0.47 ENST00000238558.3
GSC
goosecoid homeobox
chr6_-_30658745 0.45 ENST00000376420.5
ENST00000376421.5
NRM
nurim (nuclear envelope membrane protein)
chr17_+_43318434 0.45 ENST00000587489.1
FMNL1
formin-like 1
chr14_+_96722152 0.44 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr14_-_58894332 0.44 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr11_-_62752455 0.43 ENST00000360421.4
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr2_+_219472637 0.42 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr7_+_80231466 0.42 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr18_-_64271363 0.42 ENST00000262150.2
CDH19
cadherin 19, type 2
chr1_+_62439037 0.42 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr19_-_42931567 0.42 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr18_+_616672 0.42 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr9_-_95244781 0.40 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr5_-_41510656 0.40 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr1_-_150208363 0.40 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_150208291 0.40 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr5_-_41510725 0.39 ENST00000328457.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr7_+_28452130 0.39 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr7_+_93535866 0.39 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr18_+_32290218 0.39 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr3_+_50649302 0.38 ENST00000446044.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr2_+_85822839 0.38 ENST00000441634.1
RNF181
ring finger protein 181
chr11_-_111783595 0.38 ENST00000528628.1
CRYAB
crystallin, alpha B
chr5_+_145718587 0.38 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr6_-_138893661 0.37 ENST00000427025.2
NHSL1
NHS-like 1
chr11_-_62752429 0.36 ENST00000377871.3
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr5_-_11589131 0.36 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr8_-_25281747 0.35 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr14_-_22005062 0.35 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr1_-_39395165 0.35 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr11_+_72975524 0.34 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr18_+_616711 0.34 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr11_+_72975578 0.34 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_-_71640227 0.33 ENST00000388726.3
ENST00000392650.3
SDK2
sidekick cell adhesion molecule 2
chr9_+_103204553 0.33 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_+_72975559 0.33 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_+_192141611 0.33 ENST00000392316.1
MYO1B
myosin IB
chr11_+_128563652 0.33 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr4_-_153601136 0.32 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr15_+_93443419 0.32 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr6_-_88411911 0.31 ENST00000257787.5
AKIRIN2
akirin 2
chr2_-_119605253 0.31 ENST00000295206.6
EN1
engrailed homeobox 1
chr5_-_11588907 0.31 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr16_+_8715536 0.31 ENST00000563958.1
ENST00000381920.3
ENST00000564554.1
METTL22
methyltransferase like 22
chr18_-_35145728 0.31 ENST00000361795.5
ENST00000603232.1
CELF4
CUGBP, Elav-like family member 4
chr9_-_131486367 0.30 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr2_+_120770581 0.29 ENST00000263713.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr9_+_18474098 0.29 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr1_+_153651078 0.29 ENST00000368680.3
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr3_-_50649192 0.29 ENST00000443053.2
ENST00000348721.3
CISH
cytokine inducible SH2-containing protein
chr8_-_80993010 0.28 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr17_+_7905912 0.28 ENST00000254854.4
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr12_+_81101277 0.28 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr16_+_81272287 0.28 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr2_-_70780572 0.28 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr2_+_201170703 0.28 ENST00000358677.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chrX_+_79675965 0.28 ENST00000308293.5
FAM46D
family with sequence similarity 46, member D
chr10_-_76868931 0.27 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr15_+_58430567 0.26 ENST00000536493.1
AQP9
aquaporin 9
chr20_+_59654146 0.26 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr19_-_48547294 0.26 ENST00000293255.2
CABP5
calcium binding protein 5
chr3_-_137851220 0.25 ENST00000236709.3
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr19_+_56166360 0.24 ENST00000308924.4
U2AF2
U2 small nuclear RNA auxiliary factor 2
chr1_-_150208412 0.24 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chrX_+_28605516 0.24 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr11_-_36619771 0.24 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2
recombination activating gene 2
chr15_+_58430368 0.24 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr6_+_31555045 0.23 ENST00000396101.3
ENST00000490742.1
LST1
leukocyte specific transcript 1
chr10_+_52751010 0.23 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr13_-_33780133 0.22 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr19_+_39989580 0.22 ENST00000596614.1
ENST00000205143.4
DLL3
delta-like 3 (Drosophila)
chr11_-_75017734 0.22 ENST00000532525.1
ARRB1
arrestin, beta 1
chrX_-_153363125 0.22 ENST00000407218.1
ENST00000453960.2
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chrY_+_16634483 0.22 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr1_-_53608289 0.22 ENST00000371491.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr3_-_98241358 0.21 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr12_-_52604607 0.21 ENST00000551894.1
ENST00000553017.1
C12orf80
chromosome 12 open reading frame 80
chr19_+_39989535 0.21 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr20_-_31124186 0.21 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr10_+_24528108 0.21 ENST00000438429.1
KIAA1217
KIAA1217
chr2_-_89459813 0.21 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr10_+_102505468 0.21 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chr8_-_133123406 0.21 ENST00000434736.2
HHLA1
HERV-H LTR-associating 1
chr2_+_201170596 0.20 ENST00000439084.1
ENST00000409718.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr10_+_103986085 0.20 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr1_-_11751665 0.20 ENST00000376667.3
ENST00000235310.3
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr18_-_70532906 0.20 ENST00000299430.2
ENST00000397929.1
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr1_-_11751529 0.20 ENST00000376672.1
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr5_-_36301984 0.19 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr10_+_95372289 0.19 ENST00000371447.3
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chrX_-_21676442 0.19 ENST00000379499.2
KLHL34
kelch-like family member 34
chr17_-_39661849 0.19 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr1_+_81771806 0.18 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr1_+_144989309 0.18 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr15_-_65407524 0.18 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr2_+_33661382 0.18 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_173174681 0.18 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr3_+_130279178 0.18 ENST00000358511.6
ENST00000453409.2
COL6A6
collagen, type VI, alpha 6
chr11_-_111794446 0.17 ENST00000527950.1
CRYAB
crystallin, alpha B
chr19_-_3479086 0.17 ENST00000587847.1
C19orf77
chromosome 19 open reading frame 77
chrX_-_54384425 0.17 ENST00000375169.3
ENST00000354646.2
WNK3
WNK lysine deficient protein kinase 3
chr12_-_14849470 0.17 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr15_-_31453157 0.16 ENST00000559177.1
ENST00000558445.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr21_-_35016231 0.16 ENST00000438788.1
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr18_-_21891460 0.16 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr1_-_150208498 0.16 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr8_+_42873548 0.16 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr9_+_18474163 0.16 ENST00000380566.4
ADAMTSL1
ADAMTS-like 1
chr2_+_85822857 0.16 ENST00000306368.4
ENST00000414390.1
ENST00000456023.1
RNF181
ring finger protein 181
chr12_-_110937351 0.16 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr2_-_14541060 0.15 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr7_-_129592700 0.15 ENST00000472396.1
ENST00000355621.3
UBE2H
ubiquitin-conjugating enzyme E2H
chr2_-_55237484 0.15 ENST00000394609.2
RTN4
reticulon 4
chr1_-_53608249 0.15 ENST00000371494.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr8_+_65492756 0.15 ENST00000321870.1
BHLHE22
basic helix-loop-helix family, member e22
chr17_+_48911942 0.14 ENST00000426127.1
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chrX_-_119077695 0.14 ENST00000371410.3
NKAP
NFKB activating protein
chr5_-_524445 0.14 ENST00000514375.1
ENST00000264938.3
SLC9A3
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
chr2_+_120770645 0.14 ENST00000443902.2
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr2_+_115219171 0.14 ENST00000409163.1
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr6_+_155537771 0.14 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr12_-_67197760 0.14 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr2_-_30144432 0.13 ENST00000389048.3
ALK
anaplastic lymphoma receptor tyrosine kinase
chr5_-_77072085 0.13 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
TBCA
tubulin folding cofactor A
chr1_+_244816237 0.13 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr6_-_30899924 0.13 ENST00000359086.3
SFTA2
surfactant associated 2
chr11_-_67290867 0.13 ENST00000353903.5
ENST00000294288.4
CABP2
calcium binding protein 2
chr1_-_102312517 0.13 ENST00000338858.5
OLFM3
olfactomedin 3
chr18_+_29769978 0.13 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0097254 renal tubular secretion(GO:0097254)
0.5 2.6 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 1.8 GO:0060005 vestibular reflex(GO:0060005)
0.3 0.8 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.3 2.4 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 0.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 1.6 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.2 2.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 0.5 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.7 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 16.9 GO:0070268 cornification(GO:0070268)
0.1 1.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 2.9 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.5 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 1.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 1.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.1 0.5 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.5 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 1.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.6 GO:0021824 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1 1.7 GO:0038166 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) angiotensin-activated signaling pathway(GO:0038166)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 0.6 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.7 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.4 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.4 GO:2000332 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.2 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 1.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 2.0 GO:0043486 histone exchange(GO:0043486)
0.0 1.8 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.4 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.7 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 1.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:1903970 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 1.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0060745 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) mammary gland branching involved in pregnancy(GO:0060745) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.0 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1990666 PCSK9-LDLR complex(GO:1990666) PCSK9-AnxA2 complex(GO:1990667)
0.1 1.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 2.0 GO:0000812 Swr1 complex(GO:0000812)
0.1 2.3 GO:0030057 desmosome(GO:0030057)
0.1 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 4.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 11.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.4 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0002046 opsin binding(GO:0002046)
0.3 1.4 GO:0005499 vitamin D binding(GO:0005499)
0.3 1.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.3 0.8 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.3 2.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 0.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 1.0 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.4 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.8 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.5 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 2.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.5 GO:0042835 BRE binding(GO:0042835)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 2.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.7 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.2 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 2.0 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 6.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 1.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-C chemokine binding(GO:0019957)
0.0 0.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 2.1 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 4.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation