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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PAX4

Z-value: 0.62

Motif logo

Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
ENSG00000106331.10 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg19_v2_chr7_-_127255724_1272557800.144.6e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_32407619 4.47 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr16_-_28621353 4.27 ENST00000567512.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_+_165675269 2.07 ENST00000507311.1
RP11-294O2.2
chr9_-_20622478 2.02 ENST00000355930.6
ENST00000380338.4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_-_93276582 1.96 ENST00000298966.2
single-pass membrane protein with coiled-coil domains 4
chr17_+_72270380 1.94 ENST00000582036.1
ENST00000307504.5
dynein, axonemal, intermediate chain 2
chr4_-_84030996 1.89 ENST00000411416.2
placenta-specific 8
chr4_+_39184024 1.66 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WD repeat domain 19
chr6_-_130031358 1.65 ENST00000368149.2
Rho GTPase activating protein 18
chr11_-_124622134 1.61 ENST00000326621.5
V-set and immunoglobulin domain containing 2
chr11_+_86085778 1.53 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
coiled-coil domain containing 81
chr19_+_14544099 1.45 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr11_-_124622083 1.42 ENST00000403470.1
V-set and immunoglobulin domain containing 2
chr16_-_28621312 1.41 ENST00000314752.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_-_62474803 1.38 ENST00000533982.1
ENST00000360796.5
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr10_+_114135004 1.13 ENST00000393081.1
acyl-CoA synthetase long-chain family member 5
chr11_-_114466477 1.13 ENST00000375478.3
neurexophilin and PC-esterase domain family, member 4
chr15_-_40401062 1.13 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
Bcl2 modifying factor
chr17_+_72322346 1.05 ENST00000551294.1
ENST00000389916.4
kinesin family member 19
chr4_+_3465027 1.04 ENST00000389653.2
ENST00000507039.1
ENST00000340083.5
docking protein 7
chr18_-_53255766 1.04 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
transcription factor 4
chr16_-_28621298 1.03 ENST00000566189.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr16_-_84273304 1.01 ENST00000308251.4
ENST00000568181.1
potassium voltage-gated channel, subfamily G, member 4
chr9_+_92219919 0.97 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr2_-_217560248 0.96 ENST00000233813.4
insulin-like growth factor binding protein 5
chr3_-_127872625 0.95 ENST00000464873.1
RuvB-like AAA ATPase 1
chr16_-_28608364 0.94 ENST00000533150.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr2_-_170550877 0.93 ENST00000447353.1
coiled-coil domain containing 173
chr18_-_53089723 0.92 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr7_+_133812052 0.90 ENST00000285928.2
leucine-rich repeats and guanylate kinase domain containing
chr19_+_11708259 0.90 ENST00000587939.1
ENST00000588174.1
zinc finger protein 627
chr19_+_13134772 0.85 ENST00000587760.1
ENST00000585575.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_11708229 0.84 ENST00000361113.5
zinc finger protein 627
chr11_-_114466471 0.82 ENST00000424261.2
neurexophilin and PC-esterase domain family, member 4
chr7_-_130080977 0.82 ENST00000223208.5
centrosomal protein 41kDa
chr16_-_28608424 0.80 ENST00000335715.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr6_+_32605195 0.80 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr6_-_31697977 0.77 ENST00000375787.2
dimethylarginine dimethylaminohydrolase 2
chr1_-_1677358 0.77 ENST00000355439.2
ENST00000400924.1
ENST00000246421.4
solute carrier family 35, member E2
chr7_+_69064300 0.75 ENST00000342771.4
autism susceptibility candidate 2
chr4_+_30723003 0.74 ENST00000543491.1
protocadherin 7
chr16_+_69958887 0.71 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr5_-_20575959 0.69 ENST00000507958.1
cadherin 18, type 2
chr11_+_1874200 0.68 ENST00000311604.3
lymphocyte-specific protein 1
chr6_+_32605134 0.66 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
major histocompatibility complex, class II, DQ alpha 1
chr9_+_100000717 0.65 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
coiled-coil domain containing 180
chr11_+_134144139 0.65 ENST00000389887.5
galactosidase, beta 1-like 3
chr7_+_26191809 0.64 ENST00000056233.3
nuclear factor, erythroid 2-like 3
chr2_-_85839146 0.64 ENST00000306336.5
ENST00000409734.3
chromosome 2 open reading frame 68
chr20_-_34117447 0.62 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
chromosome 20 open reading frame 173
chr18_+_72922710 0.62 ENST00000322038.5
teashirt zinc finger homeobox 1
chr5_-_133304473 0.59 ENST00000231512.3
chromosome 5 open reading frame 15
chr5_-_13944652 0.58 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr9_+_27109392 0.58 ENST00000406359.4
TEK tyrosine kinase, endothelial
chr19_-_37064145 0.55 ENST00000591340.1
ENST00000334116.7
zinc finger protein 529
chr8_-_144660771 0.52 ENST00000449291.2
nicotinate phosphoribosyltransferase domain containing 1
chr2_-_191184571 0.51 ENST00000392332.3
3-hydroxyisobutyryl-CoA hydrolase
chr17_+_33895090 0.51 ENST00000592381.1
RP11-1094M14.11
chr4_+_140586922 0.48 ENST00000265498.1
ENST00000506797.1
microsomal glutathione S-transferase 2
chr12_+_122181529 0.45 ENST00000541467.1
transmembrane protein 120B
chr21_-_21630994 0.45 ENST00000436373.1
AP001171.1
chr7_+_5919458 0.45 ENST00000416608.1
oncomodulin
chr7_-_16872932 0.44 ENST00000419572.2
ENST00000412973.1
anterior gradient 2
chr7_+_72848092 0.44 ENST00000344575.3
frizzled family receptor 9
chr1_+_210001309 0.42 ENST00000491415.2
digestive organ expansion factor homolog (zebrafish)
chr11_+_120107344 0.41 ENST00000260264.4
POU class 2 homeobox 3
chr12_-_121477039 0.40 ENST00000257570.5
2'-5'-oligoadenylate synthetase-like
chr4_+_170541835 0.39 ENST00000504131.2
chloride channel, voltage-sensitive 3
chr19_-_52551814 0.38 ENST00000594154.1
ENST00000598745.1
ENST00000597273.1
zinc finger protein 432
chr12_-_121476959 0.37 ENST00000339275.5
2'-5'-oligoadenylate synthetase-like
chr4_+_170541678 0.37 ENST00000360642.3
ENST00000512813.1
chloride channel, voltage-sensitive 3
chr17_+_47448102 0.36 ENST00000576461.1
Uncharacterized protein
chr5_-_93447333 0.36 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr2_+_170550944 0.36 ENST00000359744.3
ENST00000438838.1
ENST00000438710.1
ENST00000449906.1
ENST00000498202.2
ENST00000272797.4
phosphatase, orphan 2
kelch-like family member 23
chr12_-_118406028 0.35 ENST00000425217.1
kinase suppressor of ras 2
chr12_+_118573663 0.35 ENST00000261313.2
phosphatidylethanolamine binding protein 1
chr1_-_1624083 0.35 ENST00000378662.1
ENST00000234800.6
solute carrier family 35, member E2B
chr9_-_136933615 0.35 ENST00000371834.2
bromodomain containing 3
chr17_-_42295870 0.35 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
upstream binding transcription factor, RNA polymerase I
chr20_-_52210368 0.34 ENST00000371471.2
zinc finger protein 217
chr4_-_492891 0.34 ENST00000338977.5
ENST00000511833.2
zinc finger protein 721
chr22_-_31688381 0.34 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr7_+_66386204 0.34 ENST00000341567.4
ENST00000607045.1
transmembrane protein 248
chr12_-_45269430 0.34 ENST00000395487.2
NEL-like 2 (chicken)
chr19_+_49622646 0.33 ENST00000334186.4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr20_+_277737 0.33 ENST00000382352.3
zinc finger, CCHC domain containing 3
chrX_-_102942961 0.33 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
mortality factor 4 like 2
chr12_+_110906169 0.33 ENST00000377673.5
family with sequence similarity 216, member A
chr2_-_208489707 0.33 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
methyltransferase like 21A
chr19_-_49622348 0.33 ENST00000408991.2
chromosome 19 open reading frame 73
chr16_+_53088885 0.32 ENST00000566029.1
ENST00000447540.1
chromodomain helicase DNA binding protein 9
chr2_+_47630255 0.32 ENST00000406134.1
mutS homolog 2
chr2_+_47630108 0.31 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
mutS homolog 2
chr22_-_31688431 0.30 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
phosphoinositide-3-kinase interacting protein 1
chr4_+_170541660 0.30 ENST00000513761.1
ENST00000347613.4
chloride channel, voltage-sensitive 3
chr10_-_70092671 0.30 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
phenazine biosynthesis-like protein domain containing
chr7_-_137686791 0.30 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
cAMP responsive element binding protein 3-like 2
chr19_+_49891475 0.29 ENST00000447857.3
coiled-coil domain containing 155
chr2_+_12857043 0.29 ENST00000381465.2
tribbles pseudokinase 2
chr7_-_96654133 0.28 ENST00000486603.2
ENST00000222598.4
distal-less homeobox 5
chr19_+_24216213 0.28 ENST00000594934.1
ENST00000597683.1
ENST00000342944.6
CTD-2017D11.1
zinc finger protein 254
chrM_+_5824 0.28 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr12_-_123717643 0.27 ENST00000541437.1
ENST00000606320.1
M-phase phosphoprotein 9
chr1_-_151319283 0.27 ENST00000392746.3
regulatory factor X, 5 (influences HLA class II expression)
chr9_+_134103496 0.26 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
nucleoporin 214kDa
chr8_+_41348072 0.25 ENST00000405786.2
golgin A7
chr11_+_46740730 0.25 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
coagulation factor II (thrombin)
chr20_-_44993012 0.25 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
solute carrier family 35 (GDP-fucose transporter), member C2
chrX_-_47004878 0.25 ENST00000377811.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr9_+_70971815 0.25 ENST00000396392.1
ENST00000396396.1
phosphoglucomutase 5
chr12_+_50017184 0.24 ENST00000548825.2
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr1_-_182360918 0.24 ENST00000339526.4
glutamate-ammonia ligase
chr12_-_120763739 0.24 ENST00000549767.1
phospholipase A2, group IB (pancreas)
chr12_+_31812121 0.24 ENST00000395763.3
methyltransferase like 20
chr10_+_102295616 0.23 ENST00000299163.6
hypoxia inducible factor 1, alpha subunit inhibitor
chr3_+_39424828 0.23 ENST00000273158.4
ENST00000431510.1
solute carrier family 25, member 38
chr8_+_41347915 0.23 ENST00000518270.1
ENST00000520817.1
golgin A7
chr2_+_217735493 0.23 ENST00000456163.1
HCG1816075; Uncharacterized protein
chr7_-_130080818 0.22 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
centrosomal protein 41kDa
chr5_-_58882219 0.22 ENST00000505453.1
ENST00000360047.5
phosphodiesterase 4D, cAMP-specific
chr8_-_145653885 0.22 ENST00000531032.1
ENST00000292510.4
ENST00000377348.2
ENST00000530790.1
ENST00000533806.1
vacuolar protein sorting 28 homolog (S. cerevisiae)
chrX_-_131547596 0.22 ENST00000538204.1
ENST00000370849.3
muscleblind-like splicing regulator 3
chr17_+_1674982 0.22 ENST00000572048.1
ENST00000573763.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_-_21771182 0.22 ENST00000523932.1
ENST00000544659.1
docking protein 2, 56kDa
chr6_+_34857019 0.22 ENST00000360359.3
ENST00000535627.1
ankyrin repeat and sterile alpha motif domain containing 1A
chr21_+_43933946 0.22 ENST00000352133.2
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr1_+_41157361 0.22 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
nuclear transcription factor Y, gamma
chr6_-_10694766 0.21 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
chromosome 6 open reading frame 52
chrX_-_102943022 0.21 ENST00000433176.2
mortality factor 4 like 2
chr21_+_26934165 0.21 ENST00000456917.1
MIR155 host gene (non-protein coding)
chr17_+_16284399 0.21 ENST00000535788.1
ubiquitin B
chr2_-_20251744 0.21 ENST00000175091.4
lysosomal protein transmembrane 4 alpha
chr11_+_20385231 0.21 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HIV-1 Tat interactive protein 2, 30kDa
chr7_+_69064566 0.20 ENST00000403018.2
autism susceptibility candidate 2
chr7_+_140396465 0.20 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr7_-_37488834 0.19 ENST00000310758.4
engulfment and cell motility 1
chr1_-_182360498 0.19 ENST00000417584.2
glutamate-ammonia ligase
chr3_+_51895621 0.19 ENST00000333127.3
IQ motif containing F2
chr8_-_21771214 0.19 ENST00000276420.4
docking protein 2, 56kDa
chr18_-_60986962 0.18 ENST00000333681.4
B-cell CLL/lymphoma 2
chr1_-_38156153 0.18 ENST00000464085.1
ENST00000486637.1
ENST00000358011.4
ENST00000461359.1
chromosome 1 open reading frame 109
chr2_-_85555385 0.17 ENST00000377386.3
trans-golgi network protein 2
chr11_+_22689648 0.17 ENST00000278187.3
growth arrest-specific 2
chrX_-_131547625 0.17 ENST00000394311.2
muscleblind-like splicing regulator 3
chr1_+_22889953 0.17 ENST00000374644.4
ENST00000166244.3
ENST00000538803.1
EPH receptor A8
chr10_-_70092635 0.16 ENST00000309049.4
phenazine biosynthesis-like protein domain containing
chr8_-_116681221 0.16 ENST00000395715.3
trichorhinophalangeal syndrome I
chr6_+_55039050 0.16 ENST00000370862.3
hypocretin (orexin) receptor 2
chr8_-_7673238 0.16 ENST00000335021.2
defensin, beta 107A
chrX_-_48827976 0.15 ENST00000218176.3
potassium voltage-gated channel, Shal-related subfamily, member 1
chr3_-_79816965 0.15 ENST00000464233.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_+_134274322 0.15 ENST00000367871.1
ENST00000237264.4
TBP-like 1
chr17_+_7184986 0.15 ENST00000317370.8
ENST00000571308.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr4_+_492985 0.14 ENST00000296306.7
ENST00000536264.1
ENST00000310340.5
ENST00000453061.2
ENST00000504346.1
ENST00000503111.1
ENST00000383028.4
ENST00000509768.1
phosphatidylinositol glycan anchor biosynthesis, class G
chr8_+_145215928 0.14 ENST00000528919.1
maestro heat-like repeat family member 1
chr4_+_174292058 0.14 ENST00000296504.3
Sin3A-associated protein, 30kDa
chr2_+_190526111 0.14 ENST00000607062.1
ENST00000260952.4
ENST00000425590.1
ENST00000607535.1
ENST00000420250.1
ENST00000606910.1
ENST00000607690.1
ENST00000607829.1
asparagine synthetase domain containing 1
chr13_+_76334498 0.13 ENST00000534657.1
LIM domain 7
chr19_-_53193731 0.13 ENST00000598536.1
ENST00000594682.2
ENST00000601257.1
zinc finger protein 83
chr8_-_38853990 0.13 ENST00000456845.2
ENST00000397070.2
ENST00000517872.1
ENST00000412303.1
ENST00000456397.2
TM2 domain containing 2
chrX_+_110187513 0.13 ENST00000446737.1
ENST00000425146.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr18_-_3874271 0.13 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
discs, large (Drosophila) homolog-associated protein 1
chr3_-_9921934 0.13 ENST00000423850.1
cell death-inducing DFFA-like effector c
chr1_+_145524891 0.13 ENST00000369304.3
integrin, alpha 10
chr11_+_20385327 0.12 ENST00000451739.2
ENST00000532505.1
HIV-1 Tat interactive protein 2, 30kDa
chr19_+_9361606 0.12 ENST00000456448.1
olfactory receptor, family 7, subfamily E, member 24
chr18_+_3448455 0.12 ENST00000549780.1
TGFB-induced factor homeobox 1
chr6_+_31554456 0.12 ENST00000339530.4
leukocyte specific transcript 1
chr1_-_208084729 0.11 ENST00000310833.7
ENST00000356522.4
CD34 molecule
chr12_-_110888103 0.11 ENST00000426440.1
ENST00000228825.7
actin related protein 2/3 complex, subunit 3, 21kDa
chr1_-_25291475 0.11 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr22_+_23229960 0.11 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
immunoglobulin lambda-like polypeptide 5
chr9_+_19049372 0.11 ENST00000380527.1
Ras-related GTP binding A
chr5_-_32444828 0.11 ENST00000265069.8
zinc finger RNA binding protein
chr19_-_51961702 0.11 ENST00000430817.1
ENST00000321424.3
ENST00000340550.5
sialic acid binding Ig-like lectin 8
chr11_-_35440579 0.11 ENST00000606205.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_+_104394770 0.10 ENST00000409874.4
ENST00000339063.5
tudor domain containing 9
chr1_-_109618566 0.10 ENST00000338366.5
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr6_-_32095968 0.10 ENST00000375203.3
ENST00000375201.4
activating transcription factor 6 beta
chr3_+_186383741 0.10 ENST00000232003.4
histidine-rich glycoprotein
chr17_+_16284104 0.09 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
ubiquitin B
chr1_+_41157421 0.09 ENST00000372654.1
nuclear transcription factor Y, gamma
chr1_+_168756151 0.09 ENST00000420691.1
long intergenic non-protein coding RNA 626
chr11_-_59578202 0.08 ENST00000300151.4
mitochondrial ribosomal protein L16
chr6_+_10694900 0.08 ENST00000379568.3
PAK1 interacting protein 1
chr17_-_17480779 0.07 ENST00000395782.1
phosphatidylethanolamine N-methyltransferase
chr1_-_155145721 0.07 ENST00000295682.4
keratinocyte associated protein 2
chr2_+_102972363 0.07 ENST00000409599.1
interleukin 18 receptor 1
chrX_-_31285042 0.07 ENST00000378680.2
ENST00000378723.3
dystrophin
chr19_-_6333614 0.07 ENST00000301452.4
alkaline ceramidase 1
chr7_-_96339132 0.07 ENST00000413065.1
split hand/foot malformation (ectrodactyly) type 1
chr8_+_12809093 0.07 ENST00000528753.2
KIAA1456
chr4_+_95129061 0.06 ENST00000354268.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr8_+_67344710 0.06 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
alcohol dehydrogenase, iron containing, 1
chr2_-_10830093 0.06 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
nucleolar protein 10
chr8_+_17434689 0.06 ENST00000398074.3
platelet-derived growth factor receptor-like
chr7_-_140098257 0.06 ENST00000340308.3
ENST00000447932.2
ENST00000429996.2
ENST00000469193.1
ENST00000326232.9
solute carrier family 37, member 3
chrY_+_26997726 0.06 ENST00000382296.2
deleted in azoospermia 4
chr4_-_76439596 0.06 ENST00000451788.1
ENST00000512706.1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chrX_+_66764375 0.06 ENST00000374690.3
androgen receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.4 1.7 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 8.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 1.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.3 0.8 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.2 1.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 1.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.1 2.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.6 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.6 GO:0060023 soft palate development(GO:0060023)
0.1 2.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:0060166 olfactory pit development(GO:0060166)
0.1 1.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.2 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.4 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.3 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.5 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.3 GO:1900738 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 1.0 GO:1900745 activation of MAPKKK activity(GO:0000185) positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.8 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.3 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0071611 glial cell-derived neurotrophic factor secretion(GO:0044467) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.2 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.0 0.6 GO:0097503 sialylation(GO:0097503)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0 0.1 GO:1905033 regulation of nitric oxide mediated signal transduction(GO:0010749) positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.5 GO:0019370 glutathione biosynthetic process(GO:0006750) leukotriene biosynthetic process(GO:0019370)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 2.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 1.0 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 2.5 GO:0036157 outer dynein arm(GO:0036157)
0.2 0.6 GO:0032302 MutSbeta complex(GO:0032302)
0.2 1.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.9 GO:0002177 manchette(GO:0002177)
0.1 0.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.3 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0097386 glial cell projection(GO:0097386)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.4 5.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.6 GO:0032181 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.2 1.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 2.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.6 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 1.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.3 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.0 GO:0033677 DNA/RNA helicase activity(GO:0033677)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation