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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PAX8

Z-value: 0.39

Motif logo

Transcription factors associated with PAX8

Gene Symbol Gene ID Gene Info
ENSG00000125618.12 paired box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX8hg19_v2_chr2_-_113999260_1139992740.319.2e-02Click!

Activity profile of PAX8 motif

Sorted Z-values of PAX8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51487282 0.97 ENST00000595820.1
ENST00000597707.1
ENST00000336317.4
kallikrein-related peptidase 7
chr4_+_75230853 0.70 ENST00000244869.2
epiregulin
chr19_-_36019123 0.67 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr1_-_153013588 0.64 ENST00000360379.3
small proline-rich protein 2D
chr19_-_51537982 0.55 ENST00000525263.1
kallikrein-related peptidase 12
chr19_-_51538118 0.52 ENST00000529888.1
kallikrein-related peptidase 12
chr19_-_51538148 0.51 ENST00000319590.4
ENST00000250351.4
kallikrein-related peptidase 12
chr7_-_97501706 0.48 ENST00000455086.1
ENST00000453600.1
asparagine synthetase (glutamine-hydrolyzing)
chr6_+_31126291 0.44 ENST00000376257.3
ENST00000376255.4
transcription factor 19
chr2_-_234763147 0.43 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
Holliday junction recognition protein
chr7_-_76255444 0.39 ENST00000454397.1
POM121 and ZP3 fusion
chr11_-_58343319 0.38 ENST00000395074.2
leupaxin
chr5_+_148521136 0.37 ENST00000506113.1
actin binding LIM protein family, member 3
chr19_-_35992780 0.36 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
dermokine
chr22_-_37403839 0.36 ENST00000402860.3
ENST00000381821.1
testis expressed 33
chr22_-_37403858 0.35 ENST00000405091.2
testis expressed 33
chr12_+_75874460 0.33 ENST00000266659.3
GLI pathogenesis-related 1
chr12_-_6961050 0.32 ENST00000538862.2
cell division cycle associated 3
chr12_-_6960407 0.31 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
cell division cycle associated 3
chr19_+_42301079 0.30 ENST00000596544.1
carcinoembryonic antigen-related cell adhesion molecule 3
chr10_+_135340859 0.30 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr17_-_39216344 0.29 ENST00000391418.2
keratin associated protein 2-3
chr1_+_13359819 0.28 ENST00000376168.1
PRAME family member 5
chr11_-_2170786 0.28 ENST00000300632.5
insulin-like growth factor 2 (somatomedin A)
chr19_+_35630926 0.28 ENST00000588081.1
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr1_-_214638146 0.28 ENST00000543945.1
protein tyrosine phosphatase, non-receptor type 14
chr1_+_155006300 0.27 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DC-STAMP domain containing 1
chr12_+_72058130 0.26 ENST00000547843.1
THAP domain containing, apoptosis associated protein 2
chr2_+_62900986 0.26 ENST00000405015.3
ENST00000413434.1
ENST00000426940.1
ENST00000449820.1
EH domain binding protein 1
chr1_+_182419261 0.26 ENST00000294854.8
ENST00000542961.1
regulator of G-protein signaling like 1
chr18_-_58040000 0.25 ENST00000299766.3
melanocortin 4 receptor
chr1_-_119682812 0.24 ENST00000537870.1
tryptophanyl tRNA synthetase 2, mitochondrial
chr3_+_121796697 0.23 ENST00000482356.1
ENST00000393627.2
CD86 molecule
chr8_+_27168988 0.23 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
protein tyrosine kinase 2 beta
chr1_-_186649543 0.23 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_54652060 0.23 ENST00000552562.1
chromobox homolog 5
chr16_-_28518153 0.23 ENST00000356897.1
interleukin 27
chr1_+_87012753 0.22 ENST00000370563.3
chloride channel accessory 4
chr2_-_37068530 0.22 ENST00000593798.1
Uncharacterized protein
chr6_+_43739697 0.21 ENST00000230480.6
vascular endothelial growth factor A
chr9_-_116837249 0.21 ENST00000466610.2
alpha-1-microglobulin/bikunin precursor
chr1_+_16083154 0.20 ENST00000375771.1
filamin binding LIM protein 1
chr8_+_31496809 0.19 ENST00000518104.1
ENST00000519301.1
neuregulin 1
chr4_+_156680153 0.19 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
guanylate cyclase 1, soluble, beta 3
chr11_-_105010320 0.19 ENST00000532895.1
ENST00000530950.1
caspase recruitment domain family, member 18
chr11_+_117857063 0.18 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
interleukin 10 receptor, alpha
chr11_+_5617858 0.18 ENST00000380097.3
tripartite motif containing 6
chr12_-_53074182 0.18 ENST00000252244.3
keratin 1
chr15_+_67420441 0.18 ENST00000558894.1
SMAD family member 3
chr10_+_24738355 0.18 ENST00000307544.6
KIAA1217
chr6_-_32784687 0.18 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr17_+_80332153 0.18 ENST00000313135.2
urotensin 2 receptor
chr4_+_156680143 0.18 ENST00000505154.1
guanylate cyclase 1, soluble, beta 3
chr11_+_12766583 0.17 ENST00000361985.2
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr7_-_99277610 0.17 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
cytochrome P450, family 3, subfamily A, polypeptide 5
chr12_+_26348582 0.16 ENST00000535504.1
sarcospan
chr1_-_119683251 0.16 ENST00000369426.5
ENST00000235521.4
tryptophanyl tRNA synthetase 2, mitochondrial
chr7_+_129984630 0.16 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr6_+_160542821 0.16 ENST00000366963.4
solute carrier family 22 (organic cation transporter), member 1
chrX_-_71458802 0.16 ENST00000373657.1
ENST00000334463.3
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr17_-_74023291 0.16 ENST00000586740.1
envoplakin
chr2_+_17721230 0.16 ENST00000457525.1
visinin-like 1
chr8_+_59323823 0.15 ENST00000399598.2
UBX domain protein 2B
chr9_-_21228221 0.15 ENST00000413767.2
interferon, alpha 17
chr8_+_39792474 0.14 ENST00000502986.2
indoleamine 2,3-dioxygenase 2
chrX_+_129535937 0.14 ENST00000305536.6
ENST00000370947.1
RNA binding motif protein, X-linked 2
chr15_+_89631647 0.14 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
abhydrolase domain containing 2
chr6_+_72926145 0.14 ENST00000425662.2
ENST00000453976.2
regulating synaptic membrane exocytosis 1
chr18_-_29264467 0.14 ENST00000383131.3
ENST00000237019.7
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr14_-_106610852 0.14 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr9_+_706842 0.14 ENST00000382293.3
KN motif and ankyrin repeat domains 1
chr12_+_57828521 0.14 ENST00000309668.2
inhibin, beta C
chr4_+_118955500 0.14 ENST00000296499.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_-_21059029 0.13 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2 domain containing 5
chr1_-_182573514 0.13 ENST00000367558.5
regulator of G-protein signaling 16
chr19_+_50169081 0.13 ENST00000246784.3
BCL2-like 12 (proline rich)
chr6_+_160542870 0.13 ENST00000324965.4
ENST00000457470.2
solute carrier family 22 (organic cation transporter), member 1
chr3_-_137851220 0.13 ENST00000236709.3
alpha-1,4-N-acetylglucosaminyltransferase
chr17_+_67410832 0.13 ENST00000590474.1
mitogen-activated protein kinase kinase 6
chr12_+_18891045 0.13 ENST00000317658.3
capping protein (actin filament) muscle Z-line, alpha 3
chr2_-_136288113 0.13 ENST00000401392.1
zinc finger, RAN-binding domain containing 3
chr7_-_144533074 0.13 ENST00000360057.3
ENST00000378099.3
thiamin pyrophosphokinase 1
chr12_-_56236734 0.12 ENST00000548629.1
matrix metallopeptidase 19
chr19_+_50169216 0.12 ENST00000594157.1
ENST00000600947.1
ENST00000598306.1
BCL2-like 12 (proline rich)
chr6_+_14117872 0.12 ENST00000379153.3
CD83 molecule
chr7_+_37960163 0.12 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
ependymin related 1
chr1_-_222763240 0.12 ENST00000352967.4
ENST00000391882.1
ENST00000543857.1
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr4_+_80748619 0.12 ENST00000504263.1
prostate cancer associated transcript 4 (non-protein coding)
chr2_-_26864228 0.11 ENST00000288861.4
calcium and integrin binding family member 4
chr1_-_153514241 0.11 ENST00000368718.1
ENST00000359215.1
S100 calcium binding protein A5
chr12_-_129308487 0.11 ENST00000266771.5
solute carrier family 15 (oligopeptide transporter), member 4
chr2_+_90248739 0.11 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr19_+_42300548 0.11 ENST00000344550.4
carcinoembryonic antigen-related cell adhesion molecule 3
chr1_+_197382957 0.11 ENST00000367397.1
crumbs homolog 1 (Drosophila)
chr4_+_71600144 0.10 ENST00000502653.1
RUN and FYVE domain containing 3
chr3_-_111852128 0.10 ENST00000308910.4
germinal center-associated, signaling and motility
chr17_-_3499125 0.10 ENST00000399759.3
transient receptor potential cation channel, subfamily V, member 1
chr3_+_11178779 0.10 ENST00000438284.2
histamine receptor H1
chr12_-_86650045 0.10 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_+_72922590 0.10 ENST00000523963.1
regulating synaptic membrane exocytosis 1
chr9_-_21239978 0.10 ENST00000380222.2
interferon, alpha 14
chr13_+_31309645 0.10 ENST00000380490.3
arachidonate 5-lipoxygenase-activating protein
chr6_+_63921399 0.10 ENST00000356170.3
FK506 binding protein 1C
chrX_+_151903207 0.10 ENST00000370287.3
chondrosarcoma associated gene 1
chrX_+_99839799 0.10 ENST00000373031.4
tenomodulin
chrX_-_101410762 0.09 ENST00000543160.1
ENST00000333643.3
brain expressed, X-linked 5
chr1_-_184006829 0.09 ENST00000361927.4
collagen beta(1-O)galactosyltransferase 2
chr1_-_173176452 0.09 ENST00000281834.3
tumor necrosis factor (ligand) superfamily, member 4
chr6_+_72922505 0.09 ENST00000401910.3
regulating synaptic membrane exocytosis 1
chr4_-_89951028 0.09 ENST00000506913.1
family with sequence similarity 13, member A
chr12_+_128399965 0.09 ENST00000540882.1
ENST00000542089.1
long intergenic non-protein coding RNA 507
chr2_+_185463093 0.09 ENST00000302277.6
zinc finger protein 804A
chr6_+_24126350 0.09 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
neurensin 1
chr16_-_20367584 0.09 ENST00000570689.1
uromodulin
chr12_-_56236690 0.09 ENST00000322569.4
matrix metallopeptidase 19
chr22_+_22730353 0.09 ENST00000390296.2
immunoglobulin lambda variable 5-45
chr8_-_117043 0.09 ENST00000320901.3
olfactory receptor, family 4, subfamily F, member 21
chr2_+_171036635 0.09 ENST00000484338.2
ENST00000334231.6
myosin IIIB
chr8_-_66474884 0.09 ENST00000520902.1
CTD-3025N20.2
chr8_+_49984894 0.09 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
chromosome 8 open reading frame 22
chr9_-_128246769 0.08 ENST00000444226.1
mitogen-activated protein kinase associated protein 1
chr9_+_27109133 0.08 ENST00000519097.1
ENST00000380036.4
TEK tyrosine kinase, endothelial
chr18_-_29264669 0.08 ENST00000306851.5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chrX_-_153141302 0.08 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1 cell adhesion molecule
chr6_+_117198400 0.08 ENST00000332958.2
regulatory factor X, 6
chr9_+_118950325 0.08 ENST00000534838.1
pregnancy-associated plasma protein A, pappalysin 1
chr15_-_43785274 0.08 ENST00000413546.1
tumor protein p53 binding protein 1
chr17_+_1933404 0.08 ENST00000263083.6
ENST00000571418.1
diphthamide biosynthesis 1
chr19_+_12862604 0.08 ENST00000553030.1
bestrophin 2
chr4_-_80329356 0.08 ENST00000358842.3
glycerol kinase 2
chr22_+_38082330 0.08 ENST00000359114.4
nucleolar protein 12
chr2_+_90198535 0.08 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr12_-_57410304 0.08 ENST00000441881.1
ENST00000458521.2
tachykinin 3
chr11_-_74022658 0.08 ENST00000427714.2
ENST00000331597.4
prolyl 4-hydroxylase, alpha polypeptide III
chr1_+_154300217 0.08 ENST00000368489.3
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr13_-_99174252 0.08 ENST00000376547.3
serine/threonine kinase 24
chr7_+_7606497 0.08 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
missing oocyte, meiosis regulator, homolog (Drosophila)
chr21_-_27462351 0.08 ENST00000448850.1
amyloid beta (A4) precursor protein
chr2_-_211179883 0.08 ENST00000352451.3
myosin, light chain 1, alkali; skeletal, fast
chr13_-_25746416 0.08 ENST00000515384.1
ENST00000357816.2
APC membrane recruitment protein 2
chr11_+_64323156 0.08 ENST00000377585.3
solute carrier family 22 (organic anion/urate transporter), member 11
chr10_-_104597286 0.08 ENST00000369887.3
cytochrome P450, family 17, subfamily A, polypeptide 1
chr1_+_171227069 0.07 ENST00000354841.4
flavin containing monooxygenase 1
chr2_-_37193606 0.07 ENST00000379213.2
ENST00000263918.4
striatin, calmodulin binding protein
chrY_-_20935572 0.07 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
heat shock transcription factor, Y linked 2
chr12_-_10251603 0.07 ENST00000457018.2
C-type lectin domain family 1, member A
chr20_-_1373682 0.07 ENST00000381724.3
FK506 binding protein 1A, 12kDa
chr7_-_56160625 0.07 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
phosphorylase kinase, gamma 1 (muscle)
chr11_+_107461948 0.07 ENST00000265840.7
ENST00000443271.2
ELMO/CED-12 domain containing 1
chr10_+_103912137 0.07 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
nucleolar and coiled-body phosphoprotein 1
chr11_+_20044600 0.07 ENST00000311043.8
neuron navigator 2
chr1_-_11036272 0.06 ENST00000520253.1
chromosome 1 open reading frame 127
chr8_-_101117847 0.06 ENST00000523287.1
ENST00000519092.1
regulator of G-protein signaling 22
chr16_-_18911366 0.06 ENST00000565224.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr2_+_90259593 0.06 ENST00000471857.1
immunoglobulin kappa variable 1D-8
chr19_-_7812446 0.06 ENST00000394173.4
ENST00000301357.8
CD209 molecule
chr4_+_71091786 0.06 ENST00000317987.5
follicular dendritic cell secreted protein
chr16_+_33006369 0.06 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr14_-_107114267 0.06 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr14_+_101123580 0.06 ENST00000556697.1
ENST00000360899.2
ENST00000553623.1
long intergenic non-protein coding RNA 523
chr19_-_50169064 0.06 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
interferon regulatory factor 3
chr19_-_50168962 0.06 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
interferon regulatory factor 3
chr1_-_157522180 0.06 ENST00000356953.4
ENST00000368188.2
ENST00000368190.3
ENST00000368189.3
Fc receptor-like 5
chrY_-_13524717 0.06 ENST00000331172.6
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 pseudogene 1
chr17_-_39646116 0.06 ENST00000328119.6
keratin 36
chr12_-_95044309 0.06 ENST00000261226.4
transmembrane and coiled-coil domain family 3
chr1_+_367640 0.06 ENST00000426406.1
olfactory receptor, family 4, subfamily F, member 29
chr4_+_56719782 0.05 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
exocyst complex component 1
chrY_+_20708557 0.05 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
heat shock transcription factor, Y-linked 1
chr12_-_110883346 0.05 ENST00000547365.1
actin related protein 2/3 complex, subunit 3, 21kDa
chr11_+_20044096 0.05 ENST00000533917.1
neuron navigator 2
chr8_-_7220490 0.05 ENST00000400078.2
zinc finger protein 705G
chr6_+_167704838 0.05 ENST00000366829.2
unc-93 homolog A (C. elegans)
chr8_-_124749609 0.05 ENST00000262219.6
ENST00000419625.1
annexin A13
chr12_-_11287243 0.05 ENST00000539585.1
taste receptor, type 2, member 30
chr3_-_110612323 0.05 ENST00000383686.2
Uncharacterized protein
chr10_-_126694575 0.05 ENST00000334808.6
C-terminal binding protein 2
chr17_-_44657017 0.04 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ADP-ribosylation factor-like 17A
chr11_-_47870091 0.04 ENST00000526870.1
nucleoporin 160kDa
chr17_-_34257731 0.04 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RAD52 motif 1
chr11_+_55594695 0.04 ENST00000378397.1
olfactory receptor, family 5, subfamily L, member 2
chr15_-_35088340 0.04 ENST00000290378.4
actin, alpha, cardiac muscle 1
chr17_-_34257771 0.04 ENST00000394529.3
ENST00000293273.6
RAD52 motif 1
chr3_-_110612059 0.04 ENST00000485473.1
Uncharacterized protein
chr7_+_143657027 0.04 ENST00000392899.1
olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
chr12_-_10251576 0.04 ENST00000315330.4
C-type lectin domain family 1, member A
chr2_-_29297127 0.04 ENST00000331664.5
chromosome 2 open reading frame 71
chr8_-_13372253 0.04 ENST00000316609.5
deleted in liver cancer 1
chr4_-_152682129 0.04 ENST00000512306.1
ENST00000508611.1
ENST00000515812.1
ENST00000263985.6
PET112 homolog (yeast)
chr4_-_145061788 0.04 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
glycophorin A (MNS blood group)
glycophorin B (MNS blood group)
chr6_+_167704798 0.04 ENST00000230256.3
unc-93 homolog A (C. elegans)
chr1_-_71513471 0.04 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
prostaglandin E receptor 3 (subtype EP3)
chr2_-_106013400 0.04 ENST00000409807.1
four and a half LIM domains 2
chr19_-_40228657 0.04 ENST00000221804.4
Charcot-Leyden crystal galectin
chr3_-_38835501 0.04 ENST00000449082.2
sodium channel, voltage-gated, type X, alpha subunit
chr3_-_49158218 0.04 ENST00000417901.1
ENST00000306026.5
ENST00000434032.2
ubiquitin specific peptidase 19
chr4_+_154073469 0.04 ENST00000441616.1
tripartite motif containing 2
chr11_+_60609537 0.04 ENST00000227520.5
coiled-coil domain containing 86
chr12_-_57873631 0.04 ENST00000393791.3
ENST00000356411.2
ENST00000552249.1
Rho GTPase activating protein 9
chr13_-_103426112 0.04 ENST00000376032.4
ENST00000376029.3
testis expressed 30

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.2 1.0 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.5 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.2 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.2 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.2 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.4 GO:0035803 egg coat formation(GO:0035803)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.3 GO:0010193 response to ozone(GO:0010193)
0.0 0.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.3 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.4 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.3 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.2 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 2.6 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.3 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.1 GO:2001300 lipoxin metabolic process(GO:2001300)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.3 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions