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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PBX1

Z-value: 0.76

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Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
PBX1
ENSG00000185630.14 PBX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164528866_1645288770.743.1e-06Click!

Activity profile of PBX1 motif

Sorted Z-values of PBX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_63638339 4.48 ENST00000343837.3
ENST00000469440.1
SNTN
sentan, cilia apical structure protein
chr1_+_104293028 2.92 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr1_+_104159999 2.80 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr9_+_140135665 2.68 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr18_+_44526786 2.62 ENST00000245121.5
ENST00000356157.7
KATNAL2
katanin p60 subunit A-like 2
chr4_+_69962185 2.27 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_-_147867025 2.25 ENST00000502319.1
ENST00000325106.4
ENST00000504425.1
TTC29
tetratricopeptide repeat domain 29
chr4_+_69962212 2.22 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_-_147866960 2.16 ENST00000513335.1
TTC29
tetratricopeptide repeat domain 29
chr2_-_154335300 2.09 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr10_+_51549498 1.99 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chrX_+_125953746 1.78 ENST00000371125.3
CXorf64
chromosome X open reading frame 64
chr4_+_69681710 1.74 ENST00000265403.7
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr20_+_52105495 1.66 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr11_+_71903169 1.54 ENST00000393676.3
FOLR1
folate receptor 1 (adult)
chr8_+_99076750 1.50 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr5_+_140213815 1.43 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr11_-_34937858 1.39 ENST00000278359.5
APIP
APAF1 interacting protein
chr8_+_99076509 1.29 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr5_-_42825983 1.29 ENST00000506577.1
SEPP1
selenoprotein P, plasma, 1
chr4_+_77356248 1.28 ENST00000296043.6
SHROOM3
shroom family member 3
chr22_-_39190116 1.25 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
SUN2
DNAL4
Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4
chr3_+_129158926 1.20 ENST00000347300.2
ENST00000296266.3
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr10_+_63422695 1.17 ENST00000330194.2
ENST00000389639.3
C10orf107
chromosome 10 open reading frame 107
chr3_+_129159039 1.15 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr7_-_120498357 1.07 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr3_-_112564797 0.96 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr11_-_34938039 0.94 ENST00000395787.3
APIP
APAF1 interacting protein
chr13_+_97928395 0.93 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr22_+_29138013 0.87 ENST00000216027.3
ENST00000398941.2
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone
chr7_+_23637763 0.85 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr12_+_20968608 0.85 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr11_-_114466477 0.83 ENST00000375478.3
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr1_-_152131703 0.83 ENST00000316073.3
RPTN
repetin
chr16_+_16484691 0.81 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr12_+_21168630 0.81 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr2_-_27886676 0.77 ENST00000337768.5
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr6_+_27114861 0.76 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr4_-_105416039 0.75 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr1_+_226250379 0.72 ENST00000366815.3
ENST00000366814.3
H3F3A
H3 histone, family 3A
chr4_-_70080449 0.71 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr17_+_21030260 0.71 ENST00000579303.1
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr5_+_43603229 0.71 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr19_+_44645700 0.70 ENST00000592437.1
ZNF234
zinc finger protein 234
chr2_+_12857015 0.68 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr14_+_88851874 0.66 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr15_-_37393406 0.65 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr19_+_58341656 0.64 ENST00000442832.4
ENST00000594901.1
ZNF587B
zinc finger protein 587B
chr17_+_1665345 0.64 ENST00000576406.1
ENST00000571149.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_+_148508845 0.63 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr3_-_112693759 0.62 ENST00000440122.2
ENST00000490004.1
CD200R1
CD200 receptor 1
chr17_+_58755184 0.62 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr5_+_43602750 0.62 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr3_-_161090660 0.61 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr2_+_12857043 0.61 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr8_-_108510224 0.60 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr12_-_15104040 0.58 ENST00000541644.1
ENST00000545895.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr5_+_140207536 0.57 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr14_+_24583836 0.55 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11
DDB1 and CUL4 associated factor 11
chr19_+_11485333 0.51 ENST00000312423.2
SWSAP1
SWIM-type zinc finger 7 associated protein 1
chr15_-_44069741 0.51 ENST00000319359.3
ELL3
elongation factor RNA polymerase II-like 3
chr17_+_43239231 0.50 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr16_+_19222479 0.50 ENST00000568433.1
SYT17
synaptotagmin XVII
chr6_-_167040731 0.48 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_+_56401268 0.46 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr17_+_46125707 0.44 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1
nuclear factor, erythroid 2-like 1
chr7_-_112430427 0.44 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
TMEM168
transmembrane protein 168
chr3_-_149510553 0.44 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr3_-_11645925 0.43 ENST00000413604.1
VGLL4
vestigial like 4 (Drosophila)
chr13_-_46679185 0.43 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr19_-_58400148 0.43 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
ZNF814
zinc finger protein 814
chr11_+_61717336 0.43 ENST00000378042.3
BEST1
bestrophin 1
chr12_+_133657461 0.42 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
ZNF140
zinc finger protein 140
chr7_-_112430647 0.41 ENST00000312814.6
TMEM168
transmembrane protein 168
chr5_-_10761206 0.40 ENST00000432074.2
ENST00000230895.6
DAP
death-associated protein
chr13_-_46679144 0.40 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr1_-_28241226 0.40 ENST00000373912.3
ENST00000373909.3
RPA2
replication protein A2, 32kDa
chr1_-_28241024 0.39 ENST00000313433.7
ENST00000444045.1
RPA2
replication protein A2, 32kDa
chr17_-_39296739 0.39 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr5_+_98109322 0.39 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr11_+_61717279 0.38 ENST00000378043.4
BEST1
bestrophin 1
chr17_+_45973516 0.38 ENST00000376741.4
SP2
Sp2 transcription factor
chr10_-_18948156 0.37 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B-AS1
ARL5B antisense RNA 1
chr12_+_81471816 0.37 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr14_-_74551096 0.37 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr22_-_30866564 0.36 ENST00000435069.1
ENST00000415957.2
ENST00000540910.1
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr11_-_31531121 0.35 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr14_+_23938891 0.35 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
NGDN
neuroguidin, EIF4E binding protein
chrX_+_56590002 0.34 ENST00000338222.5
UBQLN2
ubiquilin 2
chr4_-_168155169 0.34 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr9_-_14308004 0.34 ENST00000493697.1
NFIB
nuclear factor I/B
chr3_+_179280668 0.34 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chrM_+_4431 0.33 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr16_+_15596123 0.33 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr8_+_98788003 0.33 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr11_+_122753391 0.33 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr1_-_54405773 0.32 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chrX_-_70473957 0.32 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3
zinc finger, MYM-type 3
chr5_-_132073111 0.32 ENST00000403231.1
KIF3A
kinesin family member 3A
chr14_-_74551172 0.32 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr5_+_159656437 0.32 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr16_+_19079215 0.31 ENST00000544894.2
ENST00000561858.1
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr19_+_19030497 0.31 ENST00000438170.2
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr11_+_68228186 0.31 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3
protein phosphatase 6, regulatory subunit 3
chr7_+_77325738 0.30 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr19_+_46498704 0.30 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61
coiled-coil domain containing 61
chr19_+_19030478 0.30 ENST00000247003.4
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chrX_-_6453159 0.29 ENST00000381089.3
ENST00000398729.1
VCX3A
variable charge, X-linked 3A
chrX_-_70474499 0.29 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr14_+_50234309 0.29 ENST00000298307.5
KLHDC2
kelch domain containing 2
chrX_+_53123314 0.28 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5
long intergenic non-protein coding RNA 1155
chr17_+_43239191 0.28 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr4_-_140005443 0.28 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chr8_+_98788057 0.28 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr19_+_41770269 0.28 ENST00000378215.4
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr12_-_39734783 0.28 ENST00000552961.1
KIF21A
kinesin family member 21A
chr16_+_19078960 0.27 ENST00000568985.1
ENST00000566110.1
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr15_+_44069276 0.27 ENST00000381359.1
SERF2
small EDRK-rich factor 2
chr16_-_29499154 0.27 ENST00000354563.5
RP11-231C14.4
Uncharacterized protein
chr5_-_177210399 0.27 ENST00000510276.1
FAM153A
family with sequence similarity 153, member A
chr19_+_41770236 0.26 ENST00000392006.3
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr3_-_120461378 0.26 ENST00000273375.3
RABL3
RAB, member of RAS oncogene family-like 3
chr11_-_126870655 0.26 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr13_+_115079949 0.26 ENST00000361283.1
CHAMP1
chromosome alignment maintaining phosphoprotein 1
chr2_-_96971232 0.25 ENST00000323853.5
SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr12_-_122985067 0.25 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chrX_+_1734051 0.25 ENST00000381229.4
ENST00000381233.3
ASMT
acetylserotonin O-methyltransferase
chr7_-_77325545 0.24 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L-AS1
RSBN1L antisense RNA 1
chr18_-_59854203 0.23 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
PIGN
phosphatidylinositol glycan anchor biosynthesis, class N
chr7_+_75024903 0.23 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr18_+_29598335 0.23 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr11_-_40315640 0.23 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chrM_+_9207 0.23 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr16_-_20364030 0.22 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
UMOD
uromodulin
chr2_-_88427568 0.22 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr1_+_179262905 0.22 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
SOAT1
sterol O-acyltransferase 1
chr16_-_30546141 0.21 ENST00000535210.1
ENST00000395094.3
ZNF747
zinc finger protein 747
chr12_-_56848426 0.21 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr6_-_15586238 0.21 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr6_-_51952367 0.21 ENST00000340994.4
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr10_+_60028818 0.21 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr3_+_155860751 0.20 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr5_-_94417339 0.20 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_-_109605663 0.20 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr1_-_1690014 0.20 ENST00000400922.2
ENST00000342348.5
NADK
NAD kinase
chr14_+_22985251 0.20 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr3_-_143567262 0.20 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr6_-_7313381 0.19 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1
signal sequence receptor, alpha
chr19_+_35417939 0.19 ENST00000601142.1
ENST00000426813.2
ZNF30
zinc finger protein 30
chr14_-_69619823 0.19 ENST00000341516.5
DCAF5
DDB1 and CUL4 associated factor 5
chr16_-_20364122 0.19 ENST00000396138.4
ENST00000577168.1
UMOD
uromodulin
chr6_-_31560729 0.18 ENST00000340027.5
ENST00000376073.4
ENST00000376072.3
NCR3
natural cytotoxicity triggering receptor 3
chr3_-_12587055 0.18 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr4_+_187148556 0.18 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr2_-_158182410 0.18 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr6_+_26124373 0.18 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr8_-_10512569 0.17 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr10_+_124320156 0.17 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1
deleted in malignant brain tumors 1
chrX_-_110655306 0.16 ENST00000371993.2
DCX
doublecortin
chr15_+_34638066 0.16 ENST00000333756.4
NUTM1
NUT midline carcinoma, family member 1
chr17_+_73663402 0.16 ENST00000355423.3
SAP30BP
SAP30 binding protein
chr10_+_48189612 0.15 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr1_-_115323245 0.15 ENST00000060969.5
ENST00000369528.5
SIKE1
suppressor of IKBKE 1
chr13_-_22033392 0.15 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
ZDHHC20
zinc finger, DHHC-type containing 20
chr6_+_83777374 0.15 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1
dopey family member 1
chrX_-_70474377 0.15 ENST00000373978.1
ENST00000373981.1
ZMYM3
zinc finger, MYM-type 3
chrX_+_7810303 0.15 ENST00000381059.3
ENST00000341408.4
VCX
variable charge, X-linked
chr9_-_6015607 0.13 ENST00000259569.5
RANBP6
RAN binding protein 6
chr17_+_72983674 0.13 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chrM_+_10053 0.13 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr15_-_54025300 0.13 ENST00000559418.1
WDR72
WD repeat domain 72
chr6_-_27775694 0.13 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr5_-_86708833 0.12 ENST00000256897.4
CCNH
cyclin H
chr8_-_116681221 0.12 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr19_+_782755 0.12 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr5_-_86708670 0.12 ENST00000504878.1
CCNH
cyclin H
chr5_+_68513622 0.12 ENST00000512880.1
ENST00000602380.1
MRPS36
mitochondrial ribosomal protein S36
chr2_+_181845298 0.12 ENST00000410062.4
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr5_-_132073210 0.12 ENST00000378735.1
ENST00000378746.4
KIF3A
kinesin family member 3A
chr12_-_102455902 0.11 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr17_+_7758374 0.11 ENST00000301599.6
ENST00000574668.1
TMEM88
transmembrane protein 88
chr2_-_27886460 0.11 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr1_-_146068184 0.11 ENST00000604894.1
ENST00000369323.3
ENST00000479926.2
NBPF11
neuroblastoma breakpoint family, member 11
chr12_-_102455846 0.11 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr7_+_134331550 0.11 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM
2,3-bisphosphoglycerate mutase
chr13_-_24895566 0.10 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr9_-_32573130 0.10 ENST00000350021.2
ENST00000379847.3
NDUFB6
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr6_-_31782813 0.10 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr17_+_75181292 0.10 ENST00000431431.2
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr4_+_120056939 0.10 ENST00000307128.5
MYOZ2
myozenin 2
chr17_-_26694979 0.09 ENST00000438614.1
VTN
vitronectin
chr12_+_101988627 0.09 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr4_-_140005341 0.09 ENST00000379549.2
ENST00000512627.1
ELF2
E74-like factor 2 (ets domain transcription factor)
chr3_+_193853927 0.09 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr19_-_5903714 0.09 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr2_+_79412357 0.09 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chrX_+_95939638 0.09 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr15_+_69222827 0.09 ENST00000310673.3
ENST00000448182.3
ENST00000260364.5
SPESP1
NOX5
sperm equatorial segment protein 1
NADPH oxidase, EF-hand calcium binding domain 5
chr16_-_49890016 0.08 ENST00000563137.2
ZNF423
zinc finger protein 423
chr1_-_147610081 0.08 ENST00000369226.3
NBPF24
neuroblastoma breakpoint family, member 24

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.5 1.5 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.4 2.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 1.3 GO:0006740 NADPH regeneration(GO:0006740)
0.3 1.3 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 0.7 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.2 2.3 GO:0070269 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.2 0.8 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 1.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.2 0.7 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 3.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.6 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.7 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.9 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.6 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.6 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.4 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 1.3 GO:0045176 apical protein localization(GO:0045176)
0.1 0.6 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.1 0.3 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 1.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.9 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 2.7 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.1 GO:0042668 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.8 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.5 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.8 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 1.5 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.5 GO:0097196 Shu complex(GO:0097196)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.4 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.7 GO:0001740 Barr body(GO:0001740)
0.1 1.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.9 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.9 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0016160 amylase activity(GO:0016160)
0.4 1.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.4 1.5 GO:0061714 folic acid receptor activity(GO:0061714)
0.3 2.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.9 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 4.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 2.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0032052 bile acid binding(GO:0032052)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 1.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.0 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.0 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID MYC PATHWAY C-MYC pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 6.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER