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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PBX3

Z-value: 0.91

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Transcription factors associated with PBX3

Gene Symbol Gene ID Gene Info
ENSG00000167081.12 PBX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX3hg19_v2_chr9_+_128509624_128509658-0.588.8e-04Click!

Activity profile of PBX3 motif

Sorted Z-values of PBX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_65769392 4.49 ENST00000555736.1
CTD-2509G16.5
chr4_-_149363662 3.94 ENST00000355292.3
ENST00000358102.3
nuclear receptor subfamily 3, group C, member 2
chr3_+_63638339 2.67 ENST00000343837.3
ENST00000469440.1
sentan, cilia apical structure protein
chr6_-_46138676 2.04 ENST00000371383.2
ENST00000230565.3
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chrX_-_8700171 2.00 ENST00000262648.3
Kallmann syndrome 1 sequence
chr11_+_111385497 1.97 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
chromosome 11 open reading frame 88
chr19_-_55972936 1.83 ENST00000425675.2
ENST00000589080.1
ENST00000085068.3
isochorismatase domain containing 2
chr16_+_30210552 1.69 ENST00000338971.5
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr6_-_119670919 1.60 ENST00000368468.3
mannosidase, alpha, class 1A, member 1
chr16_+_89238149 1.53 ENST00000289746.2
cadherin 15, type 1, M-cadherin (myotubule)
chr19_+_19976683 1.51 ENST00000592725.1
zinc finger protein 253
chr5_-_160279207 1.51 ENST00000327245.5
ATPase, class V, type 10B
chr4_-_23891693 1.50 ENST00000264867.2
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr11_-_3400442 1.43 ENST00000429541.2
ENST00000532539.1
zinc finger protein 195
chr11_-_3400330 1.42 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
zinc finger protein 195
chr3_+_111393659 1.42 ENST00000477665.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr19_+_50180317 1.38 ENST00000534465.1
protein arginine methyltransferase 1
chr19_+_50706866 1.34 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr7_-_138386097 1.31 ENST00000421622.1
SVOP-like
chr1_+_85527987 1.29 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WD repeat domain 63
chr6_+_116937636 1.27 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
radial spoke head 4 homolog A (Chlamydomonas)
chr19_-_23578220 1.26 ENST00000595533.1
ENST00000397082.2
ENST00000599743.1
ENST00000300619.7
zinc finger protein 91
chr19_-_12662314 1.24 ENST00000339282.7
ENST00000596193.1
zinc finger protein 564
chr19_-_20844343 1.17 ENST00000595405.1
zinc finger protein 626
chr18_+_44526786 1.17 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chrX_-_63450480 1.16 ENST00000362002.2
ankyrin repeat and SOCS box containing 12
chr14_+_60975644 1.16 ENST00000327720.5
SIX homeobox 6
chr12_-_91573132 1.14 ENST00000550563.1
ENST00000546370.1
decorin
chr11_-_59633951 1.14 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr7_+_149571045 1.12 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATPase, H+ transporting V0 subunit e2
chr10_+_114135004 1.11 ENST00000393081.1
acyl-CoA synthetase long-chain family member 5
chr11_-_105892937 1.06 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr17_+_61699766 1.05 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
mitogen-activated protein kinase kinase kinase 3
chr2_+_63277927 1.01 ENST00000282549.2
orthodenticle homeobox 1
chr17_+_62075703 1.01 ENST00000577953.1
ENST00000582540.1
ENST00000579184.1
ENST00000425164.3
ENST00000412177.1
ENST00000539996.1
ENST00000583891.1
ENST00000580752.1
chromosome 17 open reading frame 72
chr2_-_220435963 1.01 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
obscurin-like 1
chr10_-_44144292 1.00 ENST00000374433.2
zinc finger protein 32
chr10_-_44144152 0.96 ENST00000395797.1
zinc finger protein 32
chr19_-_12405606 0.96 ENST00000356109.5
zinc finger protein 44
chr22_-_37172111 0.95 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
intraflagellar transport 27 homolog (Chlamydomonas)
chr1_-_36235529 0.94 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
claspin
chr17_+_26800756 0.94 ENST00000537681.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr19_+_22469210 0.93 ENST00000601693.1
zinc finger protein 729
chr9_-_3525968 0.92 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
regulatory factor X, 3 (influences HLA class II expression)
chr22_-_37172191 0.91 ENST00000340630.5
intraflagellar transport 27 homolog (Chlamydomonas)
chr17_+_58755184 0.90 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr17_+_26800648 0.90 ENST00000545060.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr19_-_12251202 0.89 ENST00000334213.5
zinc finger protein 20
chr3_-_187454281 0.88 ENST00000232014.4
B-cell CLL/lymphoma 6
chr16_+_67927147 0.87 ENST00000291041.5
protein serine kinase H1
chrX_-_132549506 0.86 ENST00000370828.3
glypican 4
chr22_+_17082732 0.86 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
transmembrane phosphatase with tensin homology pseudogene 1
chr7_-_16505440 0.83 ENST00000307068.4
sclerostin domain containing 1
chr11_-_73720122 0.80 ENST00000426995.2
uncoupling protein 3 (mitochondrial, proton carrier)
chr19_-_12405689 0.80 ENST00000355684.5
zinc finger protein 44
chr5_+_43602750 0.80 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
nicotinamide nucleotide transhydrogenase
chr5_+_43603229 0.79 ENST00000344920.4
ENST00000512996.2
nicotinamide nucleotide transhydrogenase
chr19_+_22469236 0.79 ENST00000357491.6
zinc finger protein 729
chr2_-_45236540 0.78 ENST00000303077.6
SIX homeobox 2
chr6_+_108487245 0.78 ENST00000368986.4
nuclear receptor subfamily 2, group E, member 1
chr19_-_22605136 0.78 ENST00000357774.5
ENST00000601553.1
ENST00000593657.1
zinc finger protein 98
chr3_-_141747950 0.75 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr19_-_12551849 0.75 ENST00000595562.1
ENST00000301547.5
Uncharacterized protein
zinc finger protein 443
chr9_-_33264676 0.74 ENST00000472232.3
ENST00000379704.2
BCL2-associated athanogene
chr9_-_124989804 0.74 ENST00000373755.2
ENST00000373754.2
LIM homeobox 6
chr3_+_88108381 0.73 ENST00000473136.1
Uncharacterized protein
chr11_-_86383370 0.73 ENST00000526834.1
ENST00000359636.2
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr9_-_119449483 0.72 ENST00000288520.5
ENST00000358637.4
ENST00000341734.4
astrotactin 2
chr14_-_61190754 0.71 ENST00000216513.4
SIX homeobox 4
chr3_-_58652523 0.70 ENST00000489857.1
ENST00000358781.2
family with sequence similarity 3, member D
chr11_-_86383157 0.70 ENST00000393324.3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr19_+_20959142 0.70 ENST00000344519.8
zinc finger protein 66
chr8_+_57124245 0.70 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
coiled-coil-helix-coiled-coil-helix domain containing 7
chr10_+_25463951 0.69 ENST00000376351.3
G protein-coupled receptor 158
chr12_-_42983478 0.69 ENST00000345127.3
ENST00000547113.1
prickle homolog 1 (Drosophila)
chr2_+_74685527 0.68 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WW domain binding protein 1
chr2_-_220436248 0.68 ENST00000265318.4
obscurin-like 1
chr19_+_19976714 0.67 ENST00000589717.1
ENST00000355650.4
zinc finger protein 253
chr2_+_74685413 0.67 ENST00000233615.2
WW domain binding protein 1
chr14_+_23938891 0.66 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
neuroguidin, EIF4E binding protein
chrX_-_7895479 0.65 ENST00000381042.4
patatin-like phospholipase domain containing 4
chr19_-_2740036 0.65 ENST00000586572.1
ENST00000269740.4
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chrX_-_7895755 0.65 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr19_-_12595586 0.64 ENST00000397732.3
zinc finger protein 709
chr7_+_134331550 0.63 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
2,3-bisphosphoglycerate mutase
chr1_+_60280458 0.63 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr8_+_105235572 0.62 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr19_+_23299777 0.62 ENST00000597761.2
zinc finger protein 730
chr17_+_46125707 0.61 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
nuclear factor, erythroid 2-like 1
chr19_+_21324827 0.61 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
zinc finger protein 431
chrX_-_154250989 0.61 ENST00000360256.4
coagulation factor VIII, procoagulant component
chr3_+_184279566 0.60 ENST00000330394.2
EPH receptor B3
chr9_-_128003606 0.59 ENST00000324460.6
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr1_+_161195781 0.59 ENST00000367988.3
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr17_+_17876127 0.59 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr3_-_52486841 0.58 ENST00000496590.1
troponin C type 1 (slow)
chr3_-_3221358 0.58 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr3_+_30647994 0.58 ENST00000295754.5
transforming growth factor, beta receptor II (70/80kDa)
chr3_+_197518100 0.58 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
leucine-rich repeats and calponin homology (CH) domain containing 3
chrX_-_117119243 0.58 ENST00000539496.1
ENST00000469946.1
kelch-like family member 13
chr19_+_11485333 0.58 ENST00000312423.2
SWIM-type zinc finger 7 associated protein 1
chr15_-_37391614 0.58 ENST00000219869.9
Meis homeobox 2
chr7_+_55433131 0.57 ENST00000254770.2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr10_+_102891048 0.57 ENST00000467928.2
T-cell leukemia homeobox 1
chr10_+_28966271 0.57 ENST00000375533.3
BMP and activin membrane-bound inhibitor
chr19_-_40931891 0.56 ENST00000357949.4
SERTA domain containing 1
chr1_-_247335269 0.56 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
zinc finger protein 124
chr4_+_6271558 0.56 ENST00000503569.1
ENST00000226760.1
Wolfram syndrome 1 (wolframin)
chr17_+_26800296 0.56 ENST00000444914.3
ENST00000314669.5
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr8_-_77912431 0.56 ENST00000357039.4
ENST00000522527.1
peroxisomal biogenesis factor 2
chr5_-_96478466 0.56 ENST00000274382.4
Lix1 homolog (chicken)
chr11_+_124055923 0.56 ENST00000318666.6
olfactory receptor, family 10, subfamily D, member 3 (non-functional)
chr19_-_20748541 0.56 ENST00000427401.4
ENST00000594419.1
zinc finger protein 737
chr2_-_239112347 0.55 ENST00000457149.1
ENST00000254654.3
integrin-linked kinase-associated serine/threonine phosphatase
chr14_-_91526922 0.55 ENST00000418736.2
ENST00000261991.3
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr19_-_19843900 0.55 ENST00000344099.3
zinc finger protein 14
chr19_-_12662240 0.55 ENST00000416136.1
ENST00000428311.1
zinc finger protein 564
ZNF709
chr17_+_61627814 0.55 ENST00000310827.4
ENST00000431926.1
ENST00000415273.2
DDB1 and CUL4 associated factor 7
chr9_+_119449576 0.54 ENST00000450136.1
ENST00000373983.2
ENST00000411410.1
tripartite motif containing 32
chr5_+_177631523 0.52 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
heterogeneous nuclear ribonucleoprotein A/B
chr3_+_169684553 0.52 ENST00000337002.4
ENST00000480708.1
SEC62 homolog (S. cerevisiae)
chr2_-_88927092 0.51 ENST00000303236.3
eukaryotic translation initiation factor 2-alpha kinase 3
chr1_+_6845384 0.51 ENST00000303635.7
calmodulin binding transcription activator 1
chr14_+_77582905 0.51 ENST00000557408.1
transmembrane protein 63C
chr4_+_155702496 0.51 ENST00000510397.1
RNA binding motif protein 46
chr16_-_29479154 0.51 ENST00000549950.1
Uncharacterized protein
chr5_+_177631497 0.50 ENST00000358344.3
heterogeneous nuclear ribonucleoprotein A/B
chr15_-_43785303 0.50 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
tumor protein p53 binding protein 1
chr3_+_158362299 0.50 ENST00000478576.1
ENST00000264263.5
ENST00000464732.1
G elongation factor, mitochondrial 1
chr11_-_73720276 0.50 ENST00000348534.4
uncoupling protein 3 (mitochondrial, proton carrier)
chr17_+_72270380 0.49 ENST00000582036.1
ENST00000307504.5
dynein, axonemal, intermediate chain 2
chr3_+_15643245 0.49 ENST00000303498.5
ENST00000437172.1
biotinidase
chr9_+_96026230 0.48 ENST00000448251.1
WNK lysine deficient protein kinase 2
chr7_-_27702455 0.48 ENST00000265395.2
3-hydroxyisobutyrate dehydrogenase
chr4_+_6202448 0.48 ENST00000508601.1
RP11-586D19.1
chr3_-_15643090 0.48 ENST00000451445.2
ENST00000421993.1
2-hydroxyacyl-CoA lyase 1
chr7_+_64254766 0.48 ENST00000307355.7
ENST00000359735.3
zinc finger protein 138
chr10_+_114710425 0.48 ENST00000352065.5
ENST00000369395.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr8_+_102504651 0.47 ENST00000251808.3
ENST00000521085.1
grainyhead-like 2 (Drosophila)
chr1_+_6845497 0.47 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr15_-_37392086 0.47 ENST00000561208.1
Meis homeobox 2
chr13_-_31736478 0.47 ENST00000445273.2
heat shock 105kDa/110kDa protein 1
chr3_-_113415441 0.47 ENST00000491165.1
ENST00000316407.4
KIAA2018
chr20_-_34330129 0.47 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RNA binding motif protein 39
chr5_+_151151504 0.47 ENST00000356245.3
ENST00000507878.2
GTPase activating protein (SH3 domain) binding protein 1
chr17_-_42019836 0.46 ENST00000225992.3
pancreatic polypeptide
chr11_-_4629388 0.46 ENST00000526337.1
ENST00000300747.5
tripartite motif containing 68
chr1_+_179050512 0.46 ENST00000367627.3
torsin family 3, member A
chr3_-_15643060 0.46 ENST00000414979.1
ENST00000435217.2
ENST00000456194.2
ENST00000457447.2
2-hydroxyacyl-CoA lyase 1
chr3_+_15643140 0.46 ENST00000449107.1
biotinidase
chr19_+_49375649 0.46 ENST00000200453.5
protein phosphatase 1, regulatory subunit 15A
chr5_+_78532003 0.46 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr21_+_17961006 0.45 ENST00000602323.1
long intergenic non-protein coding RNA 478
chr22_+_42475692 0.45 ENST00000331479.3
single-pass membrane protein with aspartate-rich tail 1
chr18_+_3448455 0.44 ENST00000549780.1
TGFB-induced factor homeobox 1
chr11_-_124981475 0.43 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr15_+_41221536 0.43 ENST00000249749.5
delta-like 4 (Drosophila)
chr19_-_21512202 0.43 ENST00000356929.3
zinc finger protein 708
chr19_+_22235310 0.42 ENST00000600162.1
zinc finger protein 257
chr7_-_64023441 0.42 ENST00000309683.6
zinc finger protein 680
chr17_-_44439084 0.42 ENST00000575960.1
ENST00000575698.1
ENST00000571246.1
ENST00000434041.2
ENST00000570618.1
ENST00000450673.3
ADP-ribosylation factor-like 17B
chr3_+_125694347 0.41 ENST00000505382.1
ENST00000511082.1
rhophilin associated tail protein 1B
chr17_-_73511584 0.41 ENST00000321617.3
CASK interacting protein 2
chr7_+_64254793 0.41 ENST00000494380.1
ENST00000440155.2
ENST00000440598.1
ENST00000437743.1
zinc finger protein 138
chr19_-_23941639 0.41 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
zinc finger protein 681
chr7_-_150652924 0.41 ENST00000330883.4
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr10_+_102790980 0.41 ENST00000393459.1
ENST00000224807.5
sideroflexin 3
chr9_-_33264557 0.41 ENST00000473781.1
ENST00000488499.1
BCL2-associated athanogene
chr4_+_331578 0.41 ENST00000512994.1
zinc finger protein 141
chr22_-_45559540 0.41 ENST00000432502.1
CTA-217C2.1
chr6_-_39082922 0.41 ENST00000229903.4
SAYSVFN motif domain containing 1
chr16_+_85061367 0.41 ENST00000538274.1
ENST00000258180.3
KIAA0513
chr20_+_60813535 0.40 ENST00000358053.2
ENST00000313733.3
ENST00000439951.2
oxysterol binding protein-like 2
chr21_+_44394620 0.40 ENST00000291547.5
PBX/knotted 1 homeobox 1
chr7_+_90338712 0.40 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr19_+_41313017 0.40 ENST00000595621.1
ENST00000595051.1
egl-9 family hypoxia-inducible factor 2
chr3_+_15643476 0.40 ENST00000436193.1
ENST00000383778.4
biotinidase
chr6_+_43028182 0.40 ENST00000394058.1
kinesin light chain 4
chr19_+_12273866 0.40 ENST00000425827.1
ENST00000439995.1
ENST00000343979.4
ENST00000398616.2
ENST00000418338.1
zinc finger protein 136
chr9_-_88897426 0.40 ENST00000375991.4
ENST00000326094.4
iron-sulfur cluster assembly 1
chr3_-_161090660 0.39 ENST00000359175.4
serine palmitoyltransferase, small subunit B
chr6_+_32146131 0.39 ENST00000375094.3
ring finger protein 5, E3 ubiquitin protein ligase
chr13_-_100624012 0.39 ENST00000267294.4
Zic family member 5
chr19_+_38924316 0.39 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
ryanodine receptor 1 (skeletal)
chr9_+_132597722 0.39 ENST00000372429.3
ENST00000315480.4
ENST00000358355.1
ubiquitin specific peptidase 20
chr3_-_88108192 0.39 ENST00000309534.6
CGG triplet repeat binding protein 1
chr13_+_20207782 0.39 ENST00000414242.2
ENST00000361479.5
M-phase phosphoprotein 8
chr19_-_23941680 0.39 ENST00000402377.3
zinc finger protein 681
chrX_+_11129388 0.39 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr14_+_54976546 0.39 ENST00000216420.7
cell growth regulator with ring finger domain 1
chr3_+_127348005 0.38 ENST00000342480.6
podocalyxin-like 2
chr19_+_58281014 0.38 ENST00000391702.3
ENST00000598885.1
ENST00000598183.1
ENST00000396154.2
ENST00000599802.1
ENST00000396150.4
zinc finger protein 586
chr3_-_112218378 0.38 ENST00000334529.5
B and T lymphocyte associated
chr14_+_39644387 0.38 ENST00000553331.1
ENST00000216832.4
pinin, desmosome associated protein
chr2_+_113670548 0.38 ENST00000263326.3
ENST00000352179.3
ENST00000349806.3
ENST00000353225.3
interleukin 37
chr3_+_30648066 0.37 ENST00000359013.4
transforming growth factor, beta receptor II (70/80kDa)
chr6_-_169654139 0.37 ENST00000366787.3
thrombospondin 2
chr7_+_64126535 0.37 ENST00000344930.3
zinc finger protein 107
chr14_+_74960423 0.37 ENST00000556816.1
ENST00000298818.8
ENST00000554924.1
iron-sulfur cluster assembly 2
chr1_+_20208870 0.37 ENST00000375120.3
OTU domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.3 2.0 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.3 1.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.3 1.0 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.3 1.6 GO:0006740 NADPH regeneration(GO:0006740)
0.3 0.9 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.3 0.9 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.3 1.6 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 1.7 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 0.7 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.2 0.9 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 0.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.6 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.8 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 0.2 GO:0030225 macrophage differentiation(GO:0030225)
0.2 0.7 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 0.9 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.2 1.0 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.2 0.8 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 1.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.6 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.1 0.6 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.4 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.3 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.4 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.4 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 1.1 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1 0.4 GO:0072554 blood vessel lumenization(GO:0072554)
0.1 0.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.5 GO:0030047 actin modification(GO:0030047)
0.1 1.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.3 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.5 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 1.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 1.2 GO:0015074 DNA integration(GO:0015074)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.7 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 1.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.2 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.9 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.6 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.1 0.3 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.1 0.3 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.1 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.4 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 1.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.6 GO:1901419 regulation of response to alcohol(GO:1901419)
0.1 1.9 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.1 0.5 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 1.2 GO:0006768 biotin metabolic process(GO:0006768)
0.1 0.7 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 2.1 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.3 GO:0010469 regulation of receptor activity(GO:0010469) regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 1.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 1.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 1.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0051025 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 1.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0098904 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) regulation of AV node cell action potential(GO:0098904) regulation of SA node cell action potential(GO:0098907) positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.6 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.6 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.6 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.4 GO:0048243 norepinephrine secretion(GO:0048243)
0.0 0.5 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.6 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.1 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0050890 cognition(GO:0050890)
0.0 2.0 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:2000617 regulation of stem cell division(GO:2000035) positive regulation of histone H3-K9 acetylation(GO:2000617)
0.0 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.3 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.0 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846)
0.0 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 2.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.9 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.2 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.0 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:0097120 receptor localization to synapse(GO:0097120)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0001534 radial spoke(GO:0001534)
0.2 1.3 GO:1990393 3M complex(GO:1990393)
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.2 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.6 GO:0097196 Shu complex(GO:0097196)
0.1 0.5 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 2.0 GO:0034709 methylosome(GO:0034709)
0.1 1.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 1.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.8 GO:0097255 R2TP complex(GO:0097255)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 1.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.7 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 0.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.5 1.6 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 1.3 GO:0047708 biotinidase activity(GO:0047708)
0.3 0.9 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 2.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.3 1.7 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.3 1.3 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.2 1.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 1.4 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 1.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.9 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.5 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.1 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.1 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.3 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.7 GO:0016887 ATPase activity(GO:0016887)
0.1 1.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.9 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 1.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 1.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 4.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0016462 pyrophosphatase activity(GO:0016462)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 4.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.9 PID BMP PATHWAY BMP receptor signaling
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 4.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 9.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.3 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors