Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for PBX3
Z-value: 0.91
Motif logo
Transcription factors associated with PBX3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PBX3 | hg19_v2_chr9_+_128509624_128509658 | -0.58 | 8.8e-04 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_-_65769392 Show fit | 4.49 |
ENST00000555736.1
|
CTD-2509G16.5 |
|
| chr4_-_149363662 Show fit | 3.94 |
ENST00000355292.3
ENST00000358102.3 |
nuclear receptor subfamily 3, group C, member 2 |
|
| chr3_+_63638339 Show fit | 2.67 |
ENST00000343837.3
ENST00000469440.1 |
sentan, cilia apical structure protein |
|
| chr6_-_46138676 Show fit | 2.04 |
ENST00000371383.2
ENST00000230565.3 |
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) |
|
| chrX_-_8700171 Show fit | 2.00 |
ENST00000262648.3
|
Kallmann syndrome 1 sequence |
|
| chr11_+_111385497 Show fit | 1.97 |
ENST00000375618.4
ENST00000529167.1 ENST00000332814.6 |
chromosome 11 open reading frame 88 |
|
| chr19_-_55972936 Show fit | 1.83 |
ENST00000425675.2
ENST00000589080.1 ENST00000085068.3 |
isochorismatase domain containing 2 |
|
| chr16_+_30210552 Show fit | 1.69 |
ENST00000338971.5
|
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 |
|
| chr6_-_119670919 Show fit | 1.60 |
ENST00000368468.3
|
mannosidase, alpha, class 1A, member 1 |
|
| chr16_+_89238149 Show fit | 1.53 |
ENST00000289746.2
|
cadherin 15, type 1, M-cadherin (myotubule) |
Network of associatons between targets according to the STRING database.
First level regulatory network of PBX3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 2.1 | GO:0048741 | skeletal muscle fiber development(GO:0048741) |
| 0.3 | 2.0 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.0 | 2.0 | GO:0006835 | dicarboxylic acid transport(GO:0006835) |
| 0.1 | 1.9 | GO:0060122 | inner ear receptor stereocilium organization(GO:0060122) |
| 0.0 | 1.9 | GO:0035082 | axoneme assembly(GO:0035082) |
| 0.2 | 1.7 | GO:0098989 | NMDA selective glutamate receptor signaling pathway(GO:0098989) |
| 0.3 | 1.6 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 0.3 | 1.6 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.1 | 1.6 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.1 | 2.0 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 1.9 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 1.7 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.1 | 1.6 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.0 | 1.5 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 1.4 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.4 | 1.3 | GO:0001534 | radial spoke(GO:0001534) |
| 0.2 | 1.3 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 1.3 | GO:0030286 | dynein complex(GO:0030286) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.7 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 4.5 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.8 | 2.4 | GO:0015361 | low-affinity sodium:dicarboxylate symporter activity(GO:0015361) |
| 0.0 | 2.2 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.3 | 2.0 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.1 | 1.8 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.3 | 1.7 | GO:0047685 | amine sulfotransferase activity(GO:0047685) |
| 0.5 | 1.6 | GO:0016652 | NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652) |
| 0.1 | 1.6 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.1 | 1.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.9 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.0 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 1.0 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.7 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.6 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.4 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 9.6 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 4.7 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 2.4 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 2.4 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 1.7 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 1.6 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 1.6 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 1.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.4 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 1.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |