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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PDX1

Z-value: 0.61

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Transcription factors associated with PDX1

Gene Symbol Gene ID Gene Info
PDX1
ENSG00000139515.5 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PDX1hg19_v2_chr13_+_28494130_284941680.311.0e-01Click!

Activity profile of PDX1 motif

Sorted Z-values of PDX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_152386732 1.25 ENST00000271835.3
CRNN
cornulin
chr12_+_107712173 0.81 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr7_-_44229022 0.73 ENST00000403799.3
GCK
glucokinase (hexokinase 4)
chr20_+_60174827 0.68 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr9_-_14722715 0.68 ENST00000380911.3
CER1
cerberus 1, DAN family BMP antagonist
chr15_+_75080883 0.62 ENST00000567571.1
CSK
c-src tyrosine kinase
chr4_-_109541539 0.60 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr1_+_62439037 0.59 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr8_-_133123406 0.58 ENST00000434736.2
HHLA1
HERV-H LTR-associating 1
chr18_+_29027696 0.58 ENST00000257189.4
DSG3
desmoglein 3
chr14_+_22985251 0.57 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr1_+_84609944 0.57 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_38911580 0.56 ENST00000312150.4
KRT25
keratin 25
chr3_-_57233966 0.55 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr18_+_28898052 0.53 ENST00000257192.4
DSG1
desmoglein 1
chr12_-_57328187 0.50 ENST00000293502.1
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr17_-_39150385 0.45 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr1_+_160160346 0.45 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr4_-_139163491 0.44 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr15_-_55562479 0.44 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr1_+_160160283 0.44 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_-_112127981 0.43 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr8_-_131399110 0.41 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr6_-_32157947 0.41 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr15_-_55563072 0.41 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr11_-_8285405 0.40 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr5_+_135394840 0.40 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr9_-_123639304 0.39 ENST00000436309.1
PHF19
PHD finger protein 19
chr4_+_86525299 0.39 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr12_+_15699286 0.38 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr4_-_140544386 0.38 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr13_-_99667960 0.38 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr2_+_48541776 0.38 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr8_+_7783859 0.37 ENST00000400120.3
ZNF705B
zinc finger protein 705B
chr12_-_54813229 0.37 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr11_+_65554493 0.37 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr9_+_125133315 0.36 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_+_56325812 0.36 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr17_-_18430160 0.36 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chr10_-_48416849 0.35 ENST00000249598.1
GDF2
growth differentiation factor 2
chr9_+_135457530 0.35 ENST00000263610.2
BARHL1
BarH-like homeobox 1
chr11_-_8290263 0.35 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr4_-_69111401 0.35 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr5_+_126984710 0.35 ENST00000379445.3
CTXN3
cortexin 3
chr17_-_9694614 0.35 ENST00000330255.5
ENST00000571134.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr12_-_6233828 0.35 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr8_-_42234745 0.34 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr9_-_136933615 0.34 ENST00000371834.2
BRD3
bromodomain containing 3
chr14_-_57272366 0.33 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr12_-_86650077 0.33 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr14_-_77889860 0.33 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr12_-_91576429 0.32 ENST00000552145.1
ENST00000546745.1
DCN
decorin
chr6_+_34204642 0.32 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr20_+_42984330 0.32 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr2_-_208031943 0.31 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr9_-_123639600 0.31 ENST00000373896.3
PHF19
PHD finger protein 19
chr7_+_129015484 0.30 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr7_-_100860851 0.30 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr3_-_98235962 0.30 ENST00000513873.1
CLDND1
claudin domain containing 1
chr9_+_125132803 0.30 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr15_-_55562582 0.30 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr15_+_28624878 0.29 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr3_-_143567262 0.29 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr12_-_53171128 0.29 ENST00000332411.2
KRT76
keratin 76
chr11_-_82444892 0.28 ENST00000329203.3
FAM181B
family with sequence similarity 181, member B
chr4_+_70796784 0.28 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr9_-_123639445 0.27 ENST00000312189.6
PHF19
PHD finger protein 19
chr21_+_17792672 0.27 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr20_+_30697298 0.27 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr15_+_58430567 0.26 ENST00000536493.1
AQP9
aquaporin 9
chr10_+_119301928 0.26 ENST00000553456.3
EMX2
empty spiracles homeobox 2
chr4_-_116034979 0.26 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr17_-_46690839 0.26 ENST00000498634.2
HOXB8
homeobox B8
chrX_-_20236970 0.26 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr15_+_58430368 0.25 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr7_+_50348268 0.25 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr20_+_62795827 0.25 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr17_-_27418537 0.25 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr7_-_14028488 0.24 ENST00000405358.4
ETV1
ets variant 1
chr12_+_28410128 0.24 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chrX_-_21676442 0.24 ENST00000379499.2
KLHL34
kelch-like family member 34
chr9_-_28670283 0.23 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr14_-_36988882 0.23 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr18_+_59000815 0.22 ENST00000262717.4
CDH20
cadherin 20, type 2
chr7_-_81399411 0.22 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr2_+_45168875 0.22 ENST00000260653.3
SIX3
SIX homeobox 3
chr4_-_39979576 0.22 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr7_-_81399355 0.22 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr4_-_123377880 0.22 ENST00000226730.4
IL2
interleukin 2
chr7_-_27169801 0.21 ENST00000511914.1
HOXA4
homeobox A4
chr20_+_43538692 0.21 ENST00000217074.4
ENST00000255136.3
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr8_-_7243080 0.21 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr7_-_14029283 0.21 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr18_-_30353025 0.21 ENST00000359358.4
KLHL14
kelch-like family member 14
chr6_+_167704838 0.21 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr12_-_52967600 0.20 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chr17_-_57229155 0.20 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr15_+_63188009 0.20 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr12_+_81110684 0.20 ENST00000228644.3
MYF5
myogenic factor 5
chr20_-_31124186 0.20 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chrX_+_7137475 0.20 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr4_+_141445311 0.20 ENST00000323570.3
ENST00000511887.2
ELMOD2
ELMO/CED-12 domain containing 2
chr21_-_35899113 0.20 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr14_+_100485712 0.20 ENST00000544450.2
EVL
Enah/Vasp-like
chr20_+_45947246 0.19 ENST00000599904.1
AL031666.2
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr2_-_112237835 0.19 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr2_+_196313239 0.19 ENST00000413290.1
AC064834.1
AC064834.1
chr6_+_29079668 0.19 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr2_+_90060377 0.19 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr20_+_43538756 0.19 ENST00000537323.1
ENST00000217073.2
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr17_-_39156138 0.19 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr15_+_62853562 0.18 ENST00000561311.1
TLN2
talin 2
chr2_-_99871570 0.18 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr3_-_74570291 0.18 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr10_+_63808970 0.18 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr13_+_102104952 0.18 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr6_+_167704798 0.18 ENST00000230256.3
UNC93A
unc-93 homolog A (C. elegans)
chr8_+_77593448 0.18 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr19_-_7968427 0.18 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr11_-_115630900 0.18 ENST00000537070.1
ENST00000499809.1
ENST00000514294.2
ENST00000535683.1
LINC00900
long intergenic non-protein coding RNA 900
chr3_-_39321512 0.18 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr2_+_87769459 0.17 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr10_-_21435488 0.17 ENST00000534331.1
ENST00000529198.1
ENST00000377118.4
C10orf113
chromosome 10 open reading frame 113
chr3_+_111718173 0.17 ENST00000494932.1
TAGLN3
transgelin 3
chr14_+_22554680 0.17 ENST00000390451.2
TRAV23DV6
T cell receptor alpha variable 23/delta variable 6
chr4_-_103749179 0.17 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_+_9953214 0.17 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr2_-_89459813 0.16 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr3_-_108248169 0.16 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr17_+_74846230 0.16 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr21_+_17442799 0.16 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr22_-_32860427 0.16 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr2_-_227050079 0.16 ENST00000423838.1
AC068138.1
AC068138.1
chr8_+_77593474 0.16 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr1_+_28586006 0.16 ENST00000253063.3
SESN2
sestrin 2
chr8_+_9953061 0.15 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr4_-_103749205 0.15 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_-_37457350 0.15 ENST00000519691.1
RP11-150O12.3
RP11-150O12.3
chr1_+_1846519 0.15 ENST00000378604.3
CALML6
calmodulin-like 6
chrX_-_110655306 0.15 ENST00000371993.2
DCX
doublecortin
chr1_-_151965048 0.15 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr4_-_119759795 0.14 ENST00000419654.2
SEC24D
SEC24 family member D
chr1_-_190446759 0.14 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_-_66536196 0.14 ENST00000511294.1
EPHA5
EPH receptor A5
chr10_+_24738355 0.14 ENST00000307544.6
KIAA1217
KIAA1217
chr19_-_47137942 0.14 ENST00000300873.4
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr10_+_11047259 0.14 ENST00000379261.4
ENST00000416382.2
CELF2
CUGBP, Elav-like family member 2
chr4_+_71587669 0.14 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr6_-_100912785 0.13 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr7_-_73038822 0.13 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL
MLX interacting protein-like
chr8_+_22424551 0.13 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr14_+_61654271 0.13 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr1_-_68698222 0.13 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr7_-_73038867 0.13 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL
MLX interacting protein-like
chr15_+_93443419 0.13 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr3_+_69985792 0.13 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr1_+_12834984 0.12 ENST00000357726.4
PRAMEF12
PRAME family member 12
chr11_-_115375107 0.12 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr14_-_69261310 0.12 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr4_-_66536057 0.11 ENST00000273854.3
EPHA5
EPH receptor A5
chr1_-_13002348 0.11 ENST00000355096.2
PRAMEF6
PRAME family member 6
chr4_-_103749313 0.11 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr19_+_641178 0.11 ENST00000166133.3
FGF22
fibroblast growth factor 22
chr21_+_17443521 0.11 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr16_+_6533729 0.11 ENST00000551752.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_-_95236551 0.11 ENST00000238558.3
GSC
goosecoid homeobox
chr6_-_111136513 0.11 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr21_+_17443434 0.10 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr15_+_69854027 0.10 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr4_+_169013666 0.10 ENST00000359299.3
ANXA10
annexin A10
chrX_-_18690210 0.10 ENST00000379984.3
RS1
retinoschisin 1
chr7_-_81399438 0.10 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr9_+_136501478 0.10 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr18_+_3447572 0.10 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr5_-_9630463 0.10 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr3_+_136649311 0.10 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr1_-_68698197 0.10 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr12_+_81101277 0.10 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chrX_-_64196376 0.10 ENST00000447788.2
ZC4H2
zinc finger, C4H2 domain containing
chr19_+_13049413 0.09 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr19_+_11071546 0.09 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr8_+_92261516 0.09 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr15_+_67841330 0.09 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chrX_-_64196307 0.09 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr16_-_52640834 0.09 ENST00000510238.3
CASC16
cancer susceptibility candidate 16 (non-protein coding)
chr4_-_103749105 0.09 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_234667504 0.09 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr5_-_142780280 0.09 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_-_102312517 0.09 ENST00000338858.5
OLFM3
olfactomedin 3
chr15_+_80351910 0.09 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr14_-_47351391 0.09 ENST00000399222.3
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr6_-_29399744 0.09 ENST00000377154.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chrX_-_100129128 0.09 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr12_-_56106060 0.09 ENST00000452168.2
ITGA7
integrin, alpha 7
chr12_-_56321649 0.09 ENST00000454792.2
ENST00000408946.2
WIBG
within bgcn homolog (Drosophila)
chr7_-_99717463 0.08 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chrX_-_64196351 0.08 ENST00000374839.3
ZC4H2
zinc finger, C4H2 domain containing
chrX_+_133930798 0.08 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr1_+_198608146 0.08 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_32908809 0.08 ENST00000324868.8
YARS2
tyrosyl-tRNA synthetase 2, mitochondrial

Network of associatons between targets according to the STRING database.

First level regulatory network of PDX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 0.7 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.2 1.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.4 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.7 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.3 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.6 GO:0097338 response to clozapine(GO:0097338)
0.1 1.0 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.9 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.6 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.2 GO:0009946 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.1 0.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.2 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0048382 mesendoderm development(GO:0048382) regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.3 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.0 GO:0051794 catagen(GO:0042637) regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.4 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0014802 terminal cisterna(GO:0014802)
0.1 1.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.5 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.3 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.7 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.7 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.2 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions