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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PKNOX1_TGIF2

Z-value: 0.51

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
PKNOX1
ENSG00000160199.10 PBX/knotted 1 homeobox 1
TGIF2
ENSG00000118707.5 TGFB induced factor homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF2hg19_v2_chr20_+_35201857_35201891,
hg19_v2_chr20_+_35201993_35202050		0.337.2e-02Click!
PKNOX1hg19_v2_chr21_+_44394620_443947370.193.2e-01Click!

Activity profile of PKNOX1_TGIF2 motif

Sorted Z-values of PKNOX1_TGIF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_34185944 1.36 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr11_+_827553 1.08 ENST00000528542.2
ENST00000450448.1
EFCAB4A
EF-hand calcium binding domain 4A
chr17_+_68071458 1.04 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr13_-_39564993 1.04 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr17_+_68071389 1.03 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_-_99869799 0.94 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr6_+_163148973 0.86 ENST00000366888.2
PACRG
PARK2 co-regulated
chr18_+_3449330 0.81 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr2_-_74779744 0.73 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr21_-_34185989 0.63 ENST00000487113.1
ENST00000382373.4
C21orf62
chromosome 21 open reading frame 62
chr6_-_24911195 0.59 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr2_-_74780176 0.59 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr4_-_105416039 0.52 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr22_+_39052632 0.52 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr5_-_132073111 0.52 ENST00000403231.1
KIF3A
kinesin family member 3A
chr15_-_37391614 0.47 ENST00000219869.9
MEIS2
Meis homeobox 2
chr15_-_37392086 0.46 ENST00000561208.1
MEIS2
Meis homeobox 2
chr17_+_39405939 0.43 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr12_+_55248289 0.42 ENST00000308796.6
MUCL1
mucin-like 1
chr14_+_100842735 0.41 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WDR25
WD repeat domain 25
chr4_-_47840112 0.41 ENST00000504584.1
CORIN
corin, serine peptidase
chr4_-_83483395 0.41 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr1_+_63989004 0.40 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr19_+_49496705 0.39 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr21_-_43735446 0.36 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr1_+_207262170 0.36 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr21_-_34186006 0.36 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr1_-_22469459 0.36 ENST00000290167.6
WNT4
wingless-type MMTV integration site family, member 4
chr16_+_618837 0.35 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr1_+_207262578 0.35 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr1_+_207262627 0.35 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr18_+_905104 0.34 ENST00000579794.1
ADCYAP1
adenylate cyclase activating polypeptide 1 (pituitary)
chr1_+_207262540 0.34 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr19_-_10764509 0.34 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr16_+_2588012 0.32 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr12_-_31882108 0.32 ENST00000281471.6
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr18_+_54318566 0.32 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr14_-_92198403 0.31 ENST00000553329.1
ENST00000256343.3
CATSPERB
catsper channel auxiliary subunit beta
chr3_-_182880541 0.31 ENST00000470251.1
ENST00000265598.3
LAMP3
lysosomal-associated membrane protein 3
chr1_-_53163992 0.31 ENST00000371538.3
SELRC1
cytochrome c oxidase assembly factor 7
chr3_-_113160334 0.31 ENST00000393845.2
ENST00000295868.2
WDR52
WD repeat domain 52
chr3_+_52828805 0.29 ENST00000416872.2
ENST00000449956.2
ITIH3
inter-alpha-trypsin inhibitor heavy chain 3
chr18_-_54305658 0.29 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr4_-_46391805 0.29 ENST00000540012.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr12_-_91398796 0.29 ENST00000261172.3
ENST00000551767.1
EPYC
epiphycan
chr17_+_76374714 0.29 ENST00000262764.6
ENST00000589689.1
ENST00000329897.7
ENST00000592043.1
ENST00000587356.1
PGS1
phosphatidylglycerophosphate synthase 1
chrX_+_49019061 0.29 ENST00000376339.1
ENST00000425661.2
ENST00000458388.1
ENST00000412696.2
MAGIX
MAGI family member, X-linked
chr4_-_149365827 0.28 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr22_-_37172111 0.28 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr16_+_4784273 0.27 ENST00000299320.5
ENST00000586724.1
C16orf71
chromosome 16 open reading frame 71
chr22_-_37172191 0.27 ENST00000340630.5
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr4_+_86396265 0.27 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr1_+_210406121 0.26 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr3_-_183273477 0.26 ENST00000341319.3
KLHL6
kelch-like family member 6
chr19_+_49496782 0.26 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr16_+_2587998 0.26 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr14_-_94856987 0.26 ENST00000449399.3
ENST00000404814.4
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_+_3668962 0.25 ENST00000294600.2
CCDC27
coiled-coil domain containing 27
chr16_-_50715196 0.25 ENST00000423026.2
SNX20
sorting nexin 20
chr2_+_234959376 0.25 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr16_+_30212378 0.24 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr12_-_67197760 0.23 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr6_+_26501449 0.23 ENST00000244513.6
BTN1A1
butyrophilin, subfamily 1, member A1
chr16_+_16484691 0.23 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr9_-_86432547 0.23 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr9_-_124989804 0.22 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr17_-_26220366 0.22 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr7_+_23637763 0.22 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chrX_-_101397433 0.22 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr19_+_49497121 0.22 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr5_+_125758813 0.22 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr7_+_73442487 0.21 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN
elastin
chr6_-_132967142 0.21 ENST00000275216.1
TAAR1
trace amine associated receptor 1
chr6_-_31651817 0.21 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr12_-_121734489 0.20 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr14_-_50474238 0.20 ENST00000399206.1
C14orf182
chromosome 14 open reading frame 182
chr16_-_69418649 0.20 ENST00000566257.1
TERF2
telomeric repeat binding factor 2
chr5_+_125758865 0.20 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr14_-_94857004 0.19 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr12_-_104531785 0.19 ENST00000551727.1
NFYB
nuclear transcription factor Y, beta
chr11_+_27062502 0.19 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_-_30457048 0.19 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr11_-_5255861 0.18 ENST00000380299.3
HBD
hemoglobin, delta
chr14_-_94856951 0.18 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_-_32920794 0.18 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr16_+_2587965 0.18 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr4_+_123653807 0.17 ENST00000314218.3
ENST00000542236.1
BBS12
Bardet-Biedl syndrome 12
chr1_+_246729724 0.17 ENST00000366513.4
ENST00000366512.3
CNST
consortin, connexin sorting protein
chr7_+_73442422 0.17 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN
elastin
chr17_+_38296576 0.17 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr4_+_146539415 0.16 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr11_+_27062272 0.16 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr12_+_104458235 0.15 ENST00000229330.4
HCFC2
host cell factor C2
chr3_-_3152031 0.15 ENST00000383846.1
ENST00000427088.1
ENST00000446632.2
ENST00000438560.1
IL5RA
interleukin 5 receptor, alpha
chr1_-_54872059 0.15 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr7_-_156685890 0.15 ENST00000353442.5
LMBR1
limb development membrane protein 1
chr12_-_121019165 0.15 ENST00000341039.2
ENST00000357500.4
POP5
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr22_+_17082732 0.15 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr12_+_122667658 0.15 ENST00000339777.4
ENST00000425921.1
LRRC43
leucine rich repeat containing 43
chr1_+_145549203 0.14 ENST00000355594.4
ENST00000544626.1
ANKRD35
ankyrin repeat domain 35
chr3_-_27763803 0.14 ENST00000449599.1
EOMES
eomesodermin
chr3_-_3221358 0.13 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr19_+_11909329 0.13 ENST00000323169.5
ENST00000450087.1
ZNF491
zinc finger protein 491
chr2_+_16080659 0.13 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr18_+_39535152 0.13 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr16_-_1429627 0.13 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr1_+_154966058 0.13 ENST00000392487.1
LENEP
lens epithelial protein
chr7_+_39605966 0.13 ENST00000223273.2
ENST00000448268.1
ENST00000432096.2
YAE1D1
Yae1 domain containing 1
chr9_-_115653176 0.13 ENST00000374228.4
SLC46A2
solute carrier family 46, member 2
chr10_+_49514698 0.13 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr7_+_73442457 0.13 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN
elastin
chr1_+_171217622 0.13 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr11_+_112046190 0.13 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2
beta-carotene oxygenase 2
chr17_+_39382900 0.13 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr16_-_50715239 0.12 ENST00000330943.4
ENST00000300590.3
SNX20
sorting nexin 20
chr21_-_30257669 0.12 ENST00000303775.5
ENST00000351429.3
N6AMT1
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr16_+_20817839 0.12 ENST00000348433.6
ENST00000568501.1
ENST00000566276.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr16_-_4784128 0.12 ENST00000592711.1
ENST00000590147.1
ENST00000304283.4
ENST00000592190.1
ENST00000589065.1
ENST00000585773.1
ENST00000450067.2
ENST00000592698.1
ENST00000586166.1
ENST00000586605.1
ENST00000592421.1
ANKS3
ankyrin repeat and sterile alpha motif domain containing 3
chr10_+_28966271 0.12 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr22_-_50219548 0.12 ENST00000404034.1
BRD1
bromodomain containing 1
chr18_+_32073253 0.12 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr3_-_52488048 0.12 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr19_+_39759154 0.12 ENST00000331982.5
IFNL2
interferon, lambda 2
chr8_-_128960591 0.12 ENST00000539634.1
TMEM75
transmembrane protein 75
chr15_-_31283798 0.12 ENST00000435680.1
ENST00000425768.1
MTMR10
myotubularin related protein 10
chr5_-_58882219 0.11 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_173043591 0.11 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1
biorientation of chromosomes in cell division 1
chr15_+_25068773 0.11 ENST00000400100.1
ENST00000400098.1
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr15_+_88120158 0.11 ENST00000560153.1
LINC00052
long intergenic non-protein coding RNA 52
chr20_+_54987305 0.11 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr21_+_31768348 0.11 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr11_-_6440283 0.11 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr3_-_169587621 0.11 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr10_+_94608245 0.11 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr6_+_26124373 0.11 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr13_+_33160553 0.11 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr16_+_20817761 0.11 ENST00000568046.1
ENST00000261377.6
AC004381.6
Putative RNA exonuclease NEF-sp
chr12_+_59989918 0.11 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr15_-_78538025 0.11 ENST00000560817.1
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr2_-_71454185 0.10 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr4_+_86396321 0.10 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr3_-_27764190 0.10 ENST00000537516.1
EOMES
eomesodermin
chr6_+_168841817 0.10 ENST00000356284.2
ENST00000354536.5
SMOC2
SPARC related modular calcium binding 2
chr3_+_52719936 0.10 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr3_-_3151664 0.10 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
IL5RA
interleukin 5 receptor, alpha
chr1_-_63988846 0.10 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr6_-_119031228 0.10 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr6_+_31865552 0.10 ENST00000469372.1
ENST00000497706.1
C2
complement component 2
chr19_+_1000418 0.10 ENST00000234389.3
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chrX_-_39923656 0.10 ENST00000413905.1
BCOR
BCL6 corepressor
chr4_+_48485341 0.10 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr9_-_134615443 0.10 ENST00000372195.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr16_+_4896659 0.10 ENST00000592120.1
UBN1
ubinuclein 1
chr20_+_54987168 0.10 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr1_-_246729544 0.09 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr4_+_88928777 0.09 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr2_+_113033164 0.09 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr5_+_43603229 0.09 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr3_+_185080908 0.09 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr11_-_101000445 0.09 ENST00000534013.1
PGR
progesterone receptor
chr2_-_203103281 0.09 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
SUMO1
small ubiquitin-like modifier 1
chr7_+_63774321 0.09 ENST00000423484.2
ZNF736
zinc finger protein 736
chr7_+_99971068 0.09 ENST00000198536.2
ENST00000453419.1
PILRA
paired immunoglobin-like type 2 receptor alpha
chr6_+_31674639 0.09 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
LY6G6F
MEGT1
lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr19_-_45826125 0.09 ENST00000221476.3
CKM
creatine kinase, muscle
chr19_-_12595586 0.08 ENST00000397732.3
ZNF709
zinc finger protein 709
chr5_-_169725231 0.08 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_+_150804676 0.08 ENST00000474524.1
ENST00000273432.4
MED12L
mediator complex subunit 12-like
chr19_-_39322299 0.08 ENST00000601094.1
ENST00000595567.1
ENST00000602115.1
ENST00000601778.1
ENST00000597205.1
ENST00000595470.1
ECH1
enoyl CoA hydratase 1, peroxisomal
chr7_+_23637118 0.08 ENST00000448353.1
CCDC126
coiled-coil domain containing 126
chr6_-_28220002 0.08 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr17_+_8191815 0.08 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr12_+_129028500 0.08 ENST00000315208.8
TMEM132C
transmembrane protein 132C
chr15_-_43785303 0.08 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1
tumor protein p53 binding protein 1
chr1_-_179112189 0.08 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr1_+_203765437 0.08 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr14_-_106330458 0.08 ENST00000461719.1
IGHJ4
immunoglobulin heavy joining 4
chr19_+_49375649 0.08 ENST00000200453.5
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr12_-_31479107 0.08 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr21_-_34144157 0.07 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr12_-_75784669 0.07 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2
calcyphosine 2
chr6_-_32140886 0.07 ENST00000395496.1
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr11_-_84028180 0.07 ENST00000280241.8
DLG2
discs, large homolog 2 (Drosophila)
chr1_-_51425902 0.07 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr11_-_64052111 0.07 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD
BCL2-associated agonist of cell death
chr2_-_3504587 0.07 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr6_-_52926539 0.07 ENST00000350082.5
ENST00000356971.3
ICK
intestinal cell (MAK-like) kinase
chr5_-_81046904 0.07 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr16_-_89556942 0.07 ENST00000301030.4
ANKRD11
ankyrin repeat domain 11
chr12_-_15114191 0.06 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr19_+_52800410 0.06 ENST00000595962.1
ENST00000598016.1
ENST00000334564.7
ENST00000490272.1
ZNF480
zinc finger protein 480
chr7_+_38217818 0.06 ENST00000009041.7
ENST00000544203.1
ENST00000434197.1
STARD3NL
STARD3 N-terminal like
chr15_+_57668695 0.06 ENST00000281282.5
CGNL1
cingulin-like 1
chr17_-_34195889 0.06 ENST00000311880.2
C17orf66
chromosome 17 open reading frame 66
chr3_+_111260954 0.06 ENST00000283285.5
CD96
CD96 molecule
chr2_-_179914760 0.06 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
CCDC141
coiled-coil domain containing 141
chr17_-_34195862 0.06 ENST00000592980.1
ENST00000587626.1
C17orf66
chromosome 17 open reading frame 66
chr11_+_64059464 0.06 ENST00000394525.2
KCNK4
potassium channel, subfamily K, member 4
chr14_-_69619689 0.06 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DCAF5
DDB1 and CUL4 associated factor 5
chr13_-_46716969 0.06 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 0.9 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 1.3 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.4 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.4 GO:0061054 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) renal vesicle induction(GO:0072034)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.3 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.3 GO:0070253 somatostatin secretion(GO:0070253)
0.1 0.2 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 2.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.5 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.0 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.9 GO:0008542 visual learning(GO:0008542)
0.0 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0002467 germinal center formation(GO:0002467)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.3 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.1 1.4 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.5 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.6 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 0.8 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 2.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.3 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane