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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU1F1

Z-value: 0.53

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Transcription factors associated with POU1F1

Gene Symbol Gene ID Gene Info
ENSG00000064835.6 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU1F1hg19_v2_chr3_-_87325612_87325654-0.301.1e-01Click!

Activity profile of POU1F1 motif

Sorted Z-values of POU1F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_13141097 1.96 ENST00000411542.1
AC011288.2
chr16_-_30122717 1.61 ENST00000566613.1
glycerophosphodiester phosphodiesterase domain containing 3
chr5_+_147691979 1.01 ENST00000274565.4
serine peptidase inhibitor, Kazal type 7 (putative)
chr1_+_115572415 0.82 ENST00000256592.1
thyroid stimulating hormone, beta
chr17_-_5321549 0.77 ENST00000572809.1
nucleoporin 88kDa
chr10_+_94352956 0.64 ENST00000260731.3
kinesin family member 11
chr8_-_91095099 0.62 ENST00000265431.3
calbindin 1, 28kDa
chr1_+_192127578 0.56 ENST00000367460.3
regulator of G-protein signaling 18
chr9_+_125133315 0.52 ENST00000223423.4
ENST00000362012.2
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr19_-_43969796 0.47 ENST00000244333.3
LY6/PLAUR domain containing 3
chr18_-_59274139 0.47 ENST00000586949.1
RP11-879F14.2
chr10_+_52152766 0.46 ENST00000596442.1
Uncharacterized protein
chr18_+_29027696 0.45 ENST00000257189.4
desmoglein 3
chr9_+_18474204 0.44 ENST00000276935.6
ADAMTS-like 1
chrX_-_11308598 0.44 ENST00000380717.3
Rho GTPase activating protein 6
chr4_-_153601136 0.40 ENST00000504064.1
ENST00000304385.3
transmembrane protein 154
chr4_-_159956333 0.40 ENST00000434826.2
chromosome 4 open reading frame 45
chr19_-_36001113 0.40 ENST00000434389.1
dermokine
chr2_-_190044480 0.40 ENST00000374866.3
collagen, type V, alpha 2
chr12_+_131438443 0.39 ENST00000261654.5
G protein-coupled receptor 133
chr15_+_67418047 0.38 ENST00000540846.2
SMAD family member 3
chr1_-_205391178 0.38 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEM domain containing 1
chr19_-_58864848 0.34 ENST00000263100.3
alpha-1-B glycoprotein
chr11_+_35201826 0.34 ENST00000531873.1
CD44 molecule (Indian blood group)
chr12_-_52761262 0.34 ENST00000257901.3
keratin 85
chrX_-_55057403 0.33 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
aminolevulinate, delta-, synthase 2
chr3_-_48130707 0.32 ENST00000360240.6
ENST00000383737.4
microtubule-associated protein 4
chr14_-_80697396 0.32 ENST00000557010.1
deiodinase, iodothyronine, type II
chr8_-_110986918 0.31 ENST00000297404.1
potassium channel, subfamily V, member 1
chr17_-_64225508 0.31 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_87012753 0.30 ENST00000370563.3
chloride channel accessory 4
chr15_+_69365265 0.30 ENST00000415504.1
long intergenic non-protein coding RNA 277
chr9_+_125132803 0.29 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_+_98900132 0.28 ENST00000520016.1
matrilin 2
chr7_-_87342564 0.26 ENST00000265724.3
ENST00000416177.1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr20_+_3776371 0.26 ENST00000245960.5
cell division cycle 25B
chr12_+_93096759 0.25 ENST00000544406.2
chromosome 12 open reading frame 74
chr13_+_32313658 0.25 ENST00000380314.1
ENST00000298386.2
relaxin/insulin-like family peptide receptor 2
chr6_-_134861089 0.25 ENST00000606039.1
RP11-557H15.4
chr4_+_71296204 0.25 ENST00000413702.1
mucin 7, secreted
chr6_+_26087646 0.25 ENST00000309234.6
hemochromatosis
chrX_+_84258832 0.24 ENST00000373173.2
apolipoprotein O-like
chr8_+_11961898 0.24 ENST00000400085.3
zinc finger protein 705D
chr11_-_5323226 0.24 ENST00000380224.1
olfactory receptor, family 51, subfamily B, member 4
chr12_+_12510352 0.24 ENST00000298571.6
loss of heterozygosity, 12, chromosomal region 1
chr18_+_21269556 0.23 ENST00000399516.3
laminin, alpha 3
chr5_-_88119580 0.23 ENST00000539796.1
myocyte enhancer factor 2C
chr5_+_81575281 0.23 ENST00000380167.4
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr9_-_34729457 0.23 ENST00000378788.3
family with sequence similarity 205, member A
chr6_-_49712123 0.23 ENST00000263045.4
cysteine-rich secretory protein 3
chr10_+_62538089 0.22 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr9_+_111624577 0.22 ENST00000333999.3
actin-like 7A
chr2_-_43266680 0.22 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
chr9_-_21351377 0.22 ENST00000380210.1
interferon, alpha 6
chr14_+_31046959 0.22 ENST00000547532.1
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr18_+_21269404 0.22 ENST00000313654.9
laminin, alpha 3
chr7_+_107224364 0.22 ENST00000491150.1
B-cell receptor-associated protein 29
chr12_+_93096619 0.22 ENST00000397833.3
chromosome 12 open reading frame 74
chr4_+_74347400 0.22 ENST00000226355.3
afamin
chr4_+_76481258 0.21 ENST00000311623.4
ENST00000435974.2
chromosome 4 open reading frame 26
chr9_+_12693336 0.21 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr2_-_163008903 0.21 ENST00000418842.2
ENST00000375497.3
glucagon
chr10_-_75226166 0.21 ENST00000544628.1
protein phosphatase 3, catalytic subunit, beta isozyme
chr14_-_101295407 0.21 ENST00000596284.1
AL117190.2
chr7_+_129932974 0.20 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chrX_-_32173579 0.20 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
dystrophin
chr15_+_58702742 0.20 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr11_-_117186946 0.20 ENST00000313005.6
ENST00000528053.1
beta-site APP-cleaving enzyme 1
chr6_+_26087509 0.20 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
hemochromatosis
chr12_-_11287243 0.20 ENST00000539585.1
taste receptor, type 2, member 30
chr2_-_231860596 0.20 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
SPATA3 antisense RNA 1 (head to head)
chr3_+_130650738 0.20 ENST00000504612.1
ATPase, Ca++ transporting, type 2C, member 1
chrX_+_154113317 0.19 ENST00000354461.2
H2A histone family, member B1
chr7_-_14026063 0.19 ENST00000443608.1
ENST00000438956.1
ets variant 1
chr4_+_96012614 0.18 ENST00000264568.4
bone morphogenetic protein receptor, type IB
chr2_+_58655461 0.18 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chrX_+_153533275 0.18 ENST00000426989.1
ENST00000426203.1
ENST00000369912.2
transketolase-like 1
chr10_-_99052382 0.18 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr19_-_56826157 0.18 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
zinc finger and SCAN domain containing 5A
chr20_+_30102231 0.18 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
histocompatibility (minor) 13
chrX_-_71458802 0.17 ENST00000373657.1
ENST00000334463.3
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr15_-_62937380 0.17 ENST00000560347.1
ENST00000558940.1
Uncharacterized protein
chr16_-_67217844 0.17 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895-like
chr12_-_7596735 0.17 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163 molecule-like 1
chr6_-_49712147 0.17 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr12_+_25205666 0.17 ENST00000547044.1
lymphoid-restricted membrane protein
chr1_+_8378140 0.16 ENST00000377479.2
solute carrier family 45, member 1
chr18_+_616672 0.16 ENST00000338387.7
clusterin-like 1 (retinal)
chr12_-_7656357 0.16 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163 molecule
chr17_+_61086917 0.16 ENST00000424789.2
ENST00000389520.4
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chrX_-_154689596 0.16 ENST00000369444.2
H2A histone family, member B3
chr6_+_47749718 0.16 ENST00000489301.2
ENST00000371211.2
ENST00000393699.2
opsin 5
chr11_+_55650773 0.16 ENST00000449290.2
tripartite motif-containing 51
chr1_-_67266939 0.15 ENST00000304526.2
insulin-like 5
chr11_-_107729887 0.15 ENST00000525815.1
solute carrier family 35, member F2
chr6_-_49604545 0.15 ENST00000371175.4
ENST00000229810.7
Rh-associated glycoprotein
chr5_-_36301984 0.15 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RAN binding protein 3-like
chr3_+_28390637 0.14 ENST00000420223.1
ENST00000383768.2
zinc finger, CW type with PWWP domain 2
chr19_+_54466179 0.14 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr12_+_69753448 0.14 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS domain containing 4
chr5_+_119867159 0.14 ENST00000505123.1
proline rich 16
chrX_+_154610428 0.14 ENST00000354514.4
H2A histone family, member B2
chr12_-_95510743 0.14 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chrX_-_77225135 0.14 ENST00000458128.1
phosphoglycerate mutase family member 4
chr12_-_86650045 0.13 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_-_17981462 0.13 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr8_-_57233103 0.13 ENST00000303749.3
ENST00000522671.1
short chain dehydrogenase/reductase family 16C, member 5
chr4_+_74301880 0.13 ENST00000395792.2
ENST00000226359.2
alpha-fetoprotein
chr5_-_93077293 0.13 ENST00000510627.4
POU domain class 5, transcription factor 2
chr12_-_112123524 0.13 ENST00000327551.6
BRCA1 associated protein
chr7_-_14026123 0.13 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ets variant 1
chr2_+_234826016 0.13 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr2_-_166930131 0.13 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
sodium channel, voltage-gated, type I, alpha subunit
chr12_-_118797475 0.13 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr19_+_9296279 0.12 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr14_+_61654271 0.12 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
protein kinase C, eta
chr1_+_81771806 0.12 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr2_+_161993465 0.12 ENST00000457476.1
TRAF family member-associated NFKB activator
chr3_-_160823040 0.12 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr7_-_86688990 0.12 ENST00000450689.2
KIAA1324-like
chr1_+_149754227 0.12 ENST00000444948.1
ENST00000369168.4
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr1_-_197036364 0.11 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr11_+_55578854 0.11 ENST00000333973.2
olfactory receptor, family 5, subfamily L, member 1
chr12_+_82347498 0.11 ENST00000550506.1
RP11-362A1.1
chr9_-_21482312 0.11 ENST00000448696.3
interferon, epsilon
chr6_+_114178512 0.11 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr5_+_60933634 0.11 ENST00000505642.1
chromosome 5 open reading frame 64
chr19_+_16940198 0.11 ENST00000248054.5
ENST00000596802.1
ENST00000379803.1
SIN3 transcription regulator family member B
chr3_-_160823158 0.11 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr15_+_64680003 0.11 ENST00000261884.3
thyroid hormone receptor interactor 4
chr2_-_45795145 0.10 ENST00000535761.1
S1 RNA binding domain 1
chr10_-_28623368 0.10 ENST00000441595.2
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr19_+_52873166 0.10 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
zinc finger protein 880
chr7_+_99425633 0.10 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
cytochrome P450, family 3, subfamily A, polypeptide 43
chr3_+_160939050 0.10 ENST00000493066.1
ENST00000351193.2
ENST00000472947.1
ENST00000463518.1
NMD3 ribosome export adaptor
chr2_+_152214098 0.10 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr17_+_45728427 0.10 ENST00000540627.1
karyopherin (importin) beta 1
chr4_+_186990298 0.10 ENST00000296795.3
ENST00000513189.1
toll-like receptor 3
chr5_+_115177178 0.10 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr4_+_3344141 0.10 ENST00000306648.7
regulator of G-protein signaling 12
chr10_+_18549645 0.10 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr1_-_53608289 0.10 ENST00000371491.4
solute carrier family 1 (glutamate transporter), member 7
chr1_+_109256067 0.09 ENST00000271311.2
fibronectin type III domain containing 7
chr17_+_1944790 0.09 ENST00000575162.1
diphthamide biosynthesis 1
chrX_+_150565653 0.09 ENST00000330374.6
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr7_-_140482926 0.09 ENST00000496384.2
v-raf murine sarcoma viral oncogene homolog B
chr8_+_7801144 0.09 ENST00000443676.1
zinc finger protein 705B
chr19_+_572543 0.09 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
basigin (Ok blood group)
chr19_-_22193731 0.09 ENST00000601773.1
ENST00000397126.4
ENST00000601993.1
ENST00000599916.1
zinc finger protein 208
chr16_+_28565230 0.09 ENST00000317058.3
coiled-coil domain containing 101
chr6_-_109702885 0.08 ENST00000504373.1
CD164 molecule, sialomucin
chr17_-_41050716 0.08 ENST00000417193.1
ENST00000301683.3
ENST00000436546.1
ENST00000431109.2
long intergenic non-protein coding RNA 671
chr20_+_55904815 0.08 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11 meiotic protein covalently bound to DSB
chr5_-_111754948 0.08 ENST00000261486.5
erythrocyte membrane protein band 4.1 like 4A
chr3_-_191000172 0.08 ENST00000427544.2
urotensin 2B
chr4_-_185275104 0.08 ENST00000317596.3
RP11-290F5.2
chr8_+_70404996 0.08 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr12_-_15038779 0.08 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr11_-_89224488 0.08 ENST00000534731.1
ENST00000527626.1
NADPH oxidase 4
chr4_-_139051839 0.08 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
long intergenic non-protein coding RNA 616
chr6_+_154360476 0.08 ENST00000428397.2
opioid receptor, mu 1
chr8_+_36641842 0.08 ENST00000523973.1
ENST00000399881.3
potassium channel, subfamily U, member 1
chr10_+_122610687 0.08 ENST00000263461.6
WD repeat domain 11
chr2_+_161993412 0.08 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr7_-_141957847 0.08 ENST00000552471.1
ENST00000547058.2
protease, serine, 58
chr4_+_190861993 0.08 ENST00000524583.1
ENST00000531991.2
FSHD region gene 1
chr19_-_4535233 0.08 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
perilipin 5
chr20_+_30697298 0.07 ENST00000398022.2
transmembrane 9 superfamily protein member 4
chr19_+_19144384 0.07 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr7_+_130126165 0.07 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
mesoderm specific transcript
chr16_+_48278178 0.07 ENST00000285737.4
ENST00000535754.1
lon peptidase 2, peroxisomal
chr6_+_29429217 0.07 ENST00000396792.2
olfactory receptor, family 2, subfamily H, member 1
chrX_+_43515467 0.07 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr7_+_130126012 0.07 ENST00000341441.5
mesoderm specific transcript
chr9_-_21239978 0.07 ENST00000380222.2
interferon, alpha 14
chr12_-_67197760 0.07 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
glutamate receptor interacting protein 1
chr7_-_76829125 0.07 ENST00000248598.5
fibrinogen-like 2
chr10_-_28571015 0.07 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr12_-_86650077 0.07 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_+_26104104 0.07 ENST00000377803.2
histone cluster 1, H4c
chr11_+_73498898 0.06 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
mitochondrial ribosomal protein L48
chr18_-_64271363 0.06 ENST00000262150.2
cadherin 19, type 2
chr9_-_95056010 0.06 ENST00000443024.2
isoleucyl-tRNA synthetase
chr12_-_10978957 0.06 ENST00000240619.2
taste receptor, type 2, member 10
chr10_-_115904361 0.06 ENST00000428953.1
ENST00000543782.1
chromosome 10 open reading frame 118
chr4_+_5526883 0.06 ENST00000195455.2
chromosome 4 open reading frame 6
chrX_-_106243451 0.06 ENST00000355610.4
ENST00000535534.1
MORC family CW-type zinc finger 4
chr22_-_32767017 0.06 ENST00000400234.1
RFPL3 antisense
chr7_-_112758665 0.06 ENST00000397764.3
long intergenic non-protein coding RNA 998
chr9_-_95055956 0.06 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
isoleucyl-tRNA synthetase
chr9_-_85882145 0.06 ENST00000328788.1
FERM domain containing 3
chr12_+_8309630 0.06 ENST00000396570.3
zinc finger protein 705A
chr15_-_22448819 0.06 ENST00000604066.1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr1_-_247921982 0.06 ENST00000408896.2
olfactory receptor, family 1, subfamily C, member 1
chr6_-_136788001 0.06 ENST00000544465.1
microtubule-associated protein 7
chr1_-_211307404 0.06 ENST00000367007.4
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr12_+_113796347 0.06 ENST00000545182.2
ENST00000280800.3
phospholipase B domain containing 2
chr6_-_132939317 0.05 ENST00000275191.2
trace amine associated receptor 2
chr4_+_48833234 0.05 ENST00000510824.1
ENST00000425583.2
OCIA domain containing 1
chr10_-_27529486 0.05 ENST00000375888.1
acyl-CoA binding domain containing 5

Network of associatons between targets according to the STRING database.

First level regulatory network of POU1F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.0 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.9 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.6 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.3 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0042138 meiotic DNA double-strand break processing(GO:0000706) meiotic DNA double-strand break formation(GO:0042138) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.3 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.3 GO:0051918 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of smooth muscle cell apoptotic process(GO:0034392) negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0034343 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.8 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.0 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.4 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.0 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0030849 Y chromosome(GO:0000806) autosome(GO:0030849)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0043073 male germ cell nucleus(GO:0001673) germ cell nucleus(GO:0043073)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.3 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.0 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME OPSINS Genes involved in Opsins