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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU2F1

Z-value: 1.09

Motif logo

Transcription factors associated with POU2F1

Gene Symbol Gene ID Gene Info
ENSG00000143190.17 POU class 2 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F1hg19_v2_chr1_+_167190066_1671901560.641.6e-04Click!

Activity profile of POU2F1 motif

Sorted Z-values of POU2F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_70861647 13.96 ENST00000246895.4
ENST00000381060.2
statherin
chrX_-_99665262 8.18 ENST00000373034.4
ENST00000255531.7
protocadherin 19
chr14_-_107078851 7.98 ENST00000390628.2
immunoglobulin heavy variable 1-58
chr12_-_58329819 5.30 ENST00000551421.1
RP11-620J15.3
chr1_+_104293028 5.00 ENST00000370079.3
amylase, alpha 1C (salivary)
chr5_+_140227048 4.78 ENST00000532602.1
protocadherin alpha 9
chr14_-_21270995 4.77 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
ribonuclease, RNase A family, 1 (pancreatic)
chr14_-_21270561 4.71 ENST00000412779.2
ribonuclease, RNase A family, 1 (pancreatic)
chr3_-_148939835 4.01 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr1_+_104159999 3.76 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr14_-_106642049 3.71 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr4_-_100356551 3.68 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr18_-_24722995 3.40 ENST00000581714.1
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr6_+_135502408 3.33 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr4_-_100356291 3.30 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_+_135502466 3.27 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog
chr12_-_58329888 2.98 ENST00000546580.1
RP11-620J15.3
chr10_+_91589309 2.90 ENST00000448490.1
long intergenic non-protein coding RNA 865
chrX_+_57313113 2.85 ENST00000374900.4
fatty acid amide hydrolase 2
chr10_+_91589261 2.85 ENST00000448963.1
long intergenic non-protein coding RNA 865
chr11_-_26588634 2.75 ENST00000436318.2
ENST00000281268.8
mucin 15, cell surface associated
chr11_+_6897856 2.73 ENST00000379829.2
olfactory receptor, family 10, subfamily A, member 4
chr15_-_45670924 2.63 ENST00000396659.3
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr7_+_48211048 2.33 ENST00000435803.1
ATP-binding cassette, sub-family A (ABC1), member 13
chr7_+_90338712 2.29 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr10_-_75118471 2.12 ENST00000340329.3
tetratricopeptide repeat domain 18
chr1_-_223308098 2.12 ENST00000342210.6
toll-like receptor 5
chr6_-_46922659 2.04 ENST00000265417.7
G protein-coupled receptor 116
chr5_+_125758813 2.01 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr4_-_110723194 1.94 ENST00000394635.3
complement factor I
chr4_-_110723134 1.92 ENST00000510800.1
ENST00000512148.1
complement factor I
chr4_-_110723335 1.91 ENST00000394634.2
complement factor I
chr18_-_52989217 1.90 ENST00000570287.2
transcription factor 4
chr16_-_18462221 1.87 ENST00000528301.1
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr6_+_26217159 1.87 ENST00000303910.2
histone cluster 1, H2ae
chr10_-_116286563 1.84 ENST00000369253.2
actin binding LIM protein 1
chr5_-_176326333 1.83 ENST00000292432.5
hexokinase 3 (white cell)
chr5_+_125758865 1.83 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr1_-_48866517 1.83 ENST00000371841.1
spermatogenesis associated 6
chr4_+_74702214 1.78 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chr3_-_121379739 1.65 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr14_-_106453155 1.63 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr6_+_135502501 1.61 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr12_-_7245125 1.59 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr5_-_13944652 1.56 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr11_-_110561721 1.53 ENST00000357139.3
Rho GTPase activating protein 20
chr10_-_116286656 1.45 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
actin binding LIM protein 1
chr8_+_18067602 1.44 ENST00000307719.4
ENST00000545197.1
ENST00000539092.1
ENST00000541942.1
ENST00000518029.1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr7_-_99149715 1.32 ENST00000449309.1
family with sequence similarity 200, member A
chr11_+_120107344 1.27 ENST00000260264.4
POU class 2 homeobox 3
chr3_+_32737027 1.26 ENST00000454516.2
CCR4-NOT transcription complex, subunit 10
chr9_+_108424738 1.24 ENST00000334077.3
T-cell acute lymphocytic leukemia 2
chr1_-_213020991 1.22 ENST00000332912.3
chromosome 1 open reading frame 227
chr16_+_19222479 1.19 ENST00000568433.1
synaptotagmin XVII
chr4_+_146539415 1.19 ENST00000281317.5
methylmalonic aciduria (cobalamin deficiency) cblA type
chr3_+_185046676 1.17 ENST00000428617.1
ENST00000443863.1
mitogen-activated protein kinase kinase kinase 13
chr19_+_56368803 1.15 ENST00000587891.1
NLR family, pyrin domain containing 4
chr8_-_33370607 1.14 ENST00000360742.5
ENST00000523305.1
TELO2 interacting protein 2
chr8_+_86121448 1.11 ENST00000520225.1
E2F transcription factor 5, p130-binding
chr15_-_89089860 1.10 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
de-etiolated homolog 1 (Arabidopsis)
chr5_-_111092873 1.09 ENST00000509025.1
ENST00000515855.1
neuronal regeneration related protein
chr1_-_89736434 1.07 ENST00000370459.3
guanylate binding protein 5
chr6_-_152489484 0.98 ENST00000354674.4
ENST00000539504.1
spectrin repeat containing, nuclear envelope 1
chr5_-_111093081 0.95 ENST00000453526.2
ENST00000509427.1
neuronal regeneration related protein
chr19_+_17337007 0.94 ENST00000215061.4
occludin/ELL domain containing 1
chr12_-_111358372 0.93 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr19_+_17337027 0.90 ENST00000601529.1
ENST00000600232.1
occludin/ELL domain containing 1
chr2_-_197226875 0.88 ENST00000409111.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr1_+_196621002 0.88 ENST00000367429.4
ENST00000439155.2
complement factor H
chr1_-_101360331 0.86 ENST00000416479.1
ENST00000370113.3
exostosin-like glycosyltransferase 2
chr19_-_44124019 0.83 ENST00000300811.3
zinc finger protein 428
chr6_+_122720681 0.82 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chr12_+_40618873 0.81 ENST00000298910.7
leucine-rich repeat kinase 2
chr13_+_108870714 0.78 ENST00000375898.3
abhydrolase domain containing 13
chr9_+_124088860 0.78 ENST00000373806.1
gelsolin
chr2_-_111334678 0.78 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
RANBP2-like and GRIP domain containing 6
chr7_+_55433131 0.76 ENST00000254770.2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr3_-_155524049 0.74 ENST00000534941.1
ENST00000340171.2
chromosome 3 open reading frame 33
chr6_+_147527103 0.74 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chr3_+_149530836 0.73 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
ring finger protein 13
chr19_+_58258164 0.73 ENST00000317178.5
zinc finger protein 776
chr17_-_37844267 0.72 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
post-GPI attachment to proteins 3
chr4_-_144940477 0.71 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
glycophorin B (MNS blood group)
chr2_+_110551851 0.69 ENST00000272454.6
ENST00000430736.1
ENST00000016946.3
ENST00000441344.1
RANBP2-like and GRIP domain containing 5
chr9_+_120466650 0.66 ENST00000355622.6
toll-like receptor 4
chrX_-_131262048 0.64 ENST00000298542.4
FERM domain containing 7
chrX_-_34150428 0.63 ENST00000346193.3
family with sequence similarity 47, member A
chr17_+_37844331 0.62 ENST00000578199.1
ENST00000406381.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr3_-_3221358 0.57 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr1_-_157567868 0.57 ENST00000271532.1
Fc receptor-like 4
chr6_-_15586238 0.57 ENST00000462989.2
dystrobrevin binding protein 1
chr16_-_46782221 0.55 ENST00000394809.4
myosin light chain kinase 3
chr20_+_5731083 0.55 ENST00000445603.1
ENST00000442185.1
chromosome 20 open reading frame 196
chr2_-_113191096 0.55 ENST00000496537.1
ENST00000330575.5
ENST00000302558.3
RANBP2-like and GRIP domain containing 8
chr19_-_44123734 0.53 ENST00000598676.1
zinc finger protein 428
chr9_-_140196703 0.52 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chrX_+_119384607 0.52 ENST00000326624.2
ENST00000557385.1
zinc finger and BTB domain containing 33
chr10_-_52008313 0.52 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr1_+_6615241 0.49 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
taste receptor, type 1, member 1
chr7_+_33765593 0.47 ENST00000311067.3
HCG1643653; Uncharacterized protein
chr9_-_123812542 0.47 ENST00000223642.1
complement component 5
chr9_-_21335356 0.46 ENST00000359039.4
kelch-like family member 9
chr1_+_161736072 0.45 ENST00000367942.3
activating transcription factor 6
chr7_+_64838712 0.43 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
zinc finger protein 92
chr9_+_120466610 0.42 ENST00000394487.4
toll-like receptor 4
chr2_+_109237717 0.40 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr17_+_43239231 0.40 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
hexamethylene bis-acetamide inducible 2
chrX_+_135388147 0.39 ENST00000394141.1
G protein-coupled receptor 112
chr16_+_16434185 0.39 ENST00000524823.2
Protein PKD1P1
chr14_+_21249200 0.36 ENST00000304677.2
ribonuclease, RNase A family, k6
chr3_+_157154578 0.36 ENST00000295927.3
pentraxin 3, long
chr1_+_100436065 0.35 ENST00000370153.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr7_+_64838786 0.35 ENST00000450302.2
zinc finger protein 92
chr14_-_68283291 0.35 ENST00000555452.1
ENST00000347230.4
zinc finger, FYVE domain containing 26
chr11_-_14521379 0.33 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
coatomer protein complex, subunit beta 1
chr13_+_52436111 0.32 ENST00000242819.4
coiled-coil domain containing 70
chr17_-_7387524 0.32 ENST00000311403.4
zinc finger and BTB domain containing 4
chr13_+_111855414 0.31 ENST00000375737.5
Rho guanine nucleotide exchange factor (GEF) 7
chr1_+_28562617 0.31 ENST00000497986.1
ENST00000335514.5
ENST00000468425.2
ENST00000465645.1
ATPase inhibitory factor 1
chr5_+_61874562 0.31 ENST00000334994.5
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr2_+_219524379 0.30 ENST00000443791.1
ENST00000359273.3
ENST00000392109.1
ENST00000392110.2
ENST00000423377.1
ENST00000392111.2
ENST00000412366.1
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr5_+_67588391 0.30 ENST00000523872.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_129083772 0.30 ENST00000564719.1
KIAA1024-like
chr4_+_120056939 0.30 ENST00000307128.5
myozenin 2
chr20_+_39657454 0.29 ENST00000361337.2
topoisomerase (DNA) I
chr12_-_72057571 0.29 ENST00000548100.1
zinc finger, C3H1-type containing
chr3_+_118892362 0.29 ENST00000497685.1
ENST00000264234.3
uroplakin 1B
chrX_-_6146876 0.29 ENST00000381095.3
neuroligin 4, X-linked
chr12_+_80750134 0.27 ENST00000546620.1
otogelin-like
chr10_+_13628921 0.26 ENST00000378572.3
pre-mRNA processing factor 18
chr6_+_127898312 0.26 ENST00000329722.7
chromosome 6 open reading frame 58
chr1_-_241683001 0.26 ENST00000366560.3
fumarate hydratase
chr1_-_160681593 0.25 ENST00000368045.3
ENST00000368046.3
CD48 molecule
chr10_+_13628933 0.24 ENST00000417658.1
ENST00000320054.4
pre-mRNA processing factor 18
chr1_-_169703203 0.24 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
selectin E
chr16_-_20416053 0.23 ENST00000302451.4
protein disulfide isomerase-like, testis expressed
chr18_+_3252206 0.22 ENST00000578562.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_103035102 0.22 ENST00000264260.2
interleukin 18 receptor accessory protein
chrX_-_19988382 0.21 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
chromosome X open reading frame 23
chrX_+_154254960 0.20 ENST00000369498.3
FUN14 domain containing 2
chr12_-_127174845 0.20 ENST00000540814.1
ENST00000541065.1
ENST00000541769.1
RP11-407A16.3
RP11-407A16.4
chr19_-_14682838 0.20 ENST00000215565.2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
chr3_-_149293990 0.18 ENST00000472417.1
WW domain containing transcription regulator 1
chr2_+_44001172 0.17 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
dynein, cytoplasmic 2, light intermediate chain 1
chr9_-_116065551 0.17 ENST00000297894.5
ring finger protein 183
chr2_+_169658928 0.17 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chr12_+_72056773 0.16 ENST00000308086.2
THAP domain containing, apoptosis associated protein 2
chr11_+_85359062 0.16 ENST00000532180.1
transmembrane protein 126A
chr11_-_5207612 0.15 ENST00000380367.1
olfactory receptor, family 52, subfamily A, member 1
chr5_-_133510456 0.15 ENST00000520417.1
S-phase kinase-associated protein 1
chr2_+_169659121 0.15 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
nitric oxide synthase trafficking
chr6_-_132834184 0.15 ENST00000367941.2
ENST00000367937.4
syntaxin 7
chr12_-_118796910 0.15 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr2_+_87135076 0.15 ENST00000409776.2
RANBP2-like and GRIP domain containing 1
chr1_-_6614565 0.15 ENST00000377705.5
nucleolar protein 9
chr12_-_127174806 0.14 ENST00000545853.1
ENST00000537478.1
RP11-407A16.3
chr22_+_23029188 0.13 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr17_-_29624343 0.13 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr8_-_86290333 0.12 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr1_-_226926864 0.12 ENST00000429204.1
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr5_+_150827143 0.11 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
solute carrier family 36 (proton/amino acid symporter), member 1
chr2_+_36923830 0.10 ENST00000379242.3
ENST00000389975.3
vitrin
chr21_-_33975547 0.10 ENST00000431599.1
chromosome 21 open reading frame 59
chr6_-_26033796 0.09 ENST00000259791.2
histone cluster 1, H2ab
chr5_+_112227311 0.09 ENST00000391338.1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr3_-_165555200 0.09 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr5_-_35230649 0.09 ENST00000382002.5
prolactin receptor
chr22_+_41697520 0.08 ENST00000352645.4
zinc finger CCCH-type containing 7B
chr14_-_65346555 0.08 ENST00000542895.1
ENST00000556626.1
spectrin, beta, erythrocytic
chr10_+_126630692 0.07 ENST00000359653.4
zinc finger, RAN-binding domain containing 1
chr11_-_62609281 0.06 ENST00000525239.1
ENST00000538098.2
WD repeat domain 74
chr5_+_140739537 0.06 ENST00000522605.1
protocadherin gamma subfamily B, 2
chr2_-_89459813 0.05 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr17_+_34391625 0.05 ENST00000004921.3
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
chr2_-_152684977 0.05 ENST00000428992.2
ENST00000295087.8
ADP-ribosylation factor-like 5A
chrX_-_130423386 0.04 ENST00000370903.3
immunoglobulin superfamily, member 1
chr17_+_75181292 0.04 ENST00000431431.2
SEC14-like 1 (S. cerevisiae)
chr10_-_31288398 0.04 ENST00000538351.2
zinc finger protein 438
chr17_-_55822653 0.03 ENST00000299415.2
coiled-coil domain containing 182
chr6_-_13621126 0.03 ENST00000600057.1
Uncharacterized protein
chrX_-_130423200 0.03 ENST00000361420.3
immunoglobulin superfamily, member 1
chr9_-_21202204 0.03 ENST00000239347.3
interferon, alpha 7
chr1_-_106161540 0.02 ENST00000420901.1
ENST00000610126.1
ENST00000435253.2
RP11-251P6.1
chr12_-_91546926 0.02 ENST00000550758.1
decorin
chr6_-_11779174 0.02 ENST00000379413.2
androgen-dependent TFPI-regulating protein
chr16_-_90142338 0.02 ENST00000407825.1
ENST00000449207.2
PR domain containing 7
chrX_-_130423240 0.01 ENST00000370910.1
ENST00000370901.4
immunoglobulin superfamily, member 1
chr4_-_100065440 0.01 ENST00000508393.1
ENST00000265512.7
alcohol dehydrogenase 4 (class II), pi polypeptide
chr18_+_5748793 0.01 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
chr5_+_126626498 0.00 ENST00000503335.2
ENST00000508365.1
ENST00000418761.2
ENST00000274473.6
multiple EGF-like-domains 10
chr6_-_11779014 0.00 ENST00000229583.5
androgen-dependent TFPI-regulating protein

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
2.3 7.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.9 14.0 GO:0046541 saliva secretion(GO:0046541)
0.7 2.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.5 1.1 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.5 3.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 1.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.3 1.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.2 2.6 GO:0006600 creatine metabolic process(GO:0006600)
0.2 0.8 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499) negative regulation of protein targeting to mitochondrion(GO:1903215)
0.2 0.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 0.9 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 0.5 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.2 0.8 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 4.0 GO:0006825 copper ion transport(GO:0006825)
0.1 8.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 9.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 1.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.5 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.5 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 1.0 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 3.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.6 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.6 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 1.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 12.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 6.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.4 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 1.2 GO:0021794 thalamus development(GO:0021794)
0.1 0.3 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 1.8 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 4.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 2.9 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 2.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.1 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.3 GO:0097105 brainstem development(GO:0003360) presynaptic membrane assembly(GO:0097105)
0.0 1.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.9 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.5 1.8 GO:0097224 sperm connecting piece(GO:0097224)
0.3 0.8 GO:0044753 amphisome(GO:0044753)
0.2 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 8.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.5 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 1.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 1.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 7.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 5.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)
0.0 2.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 2.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 2.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 2.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0046848 hydroxyapatite binding(GO:0046848)
1.7 7.0 GO:0004031 aldehyde oxidase activity(GO:0004031)
1.4 9.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.9 3.8 GO:0016160 amylase activity(GO:0016160)
0.7 8.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.6 3.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.4 4.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 1.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 1.8 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.9 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2 8.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.8 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.5 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 1.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.8 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 2.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.8 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.8 GO:0045159 myosin II binding(GO:0045159)
0.1 4.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 1.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 2.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 13.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 1.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 4.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 6.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 4.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 6.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.1 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling