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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU3F3_POU3F4

Z-value: 0.80

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Transcription factors associated with POU3F3_POU3F4

Gene Symbol Gene ID Gene Info
POU3F3
ENSG00000198914.2 POU class 3 homeobox 3
POU3F4
ENSG00000196767.4 POU class 3 homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU3F4hg19_v2_chrX_+_82763265_82763283-0.291.1e-01Click!
POU3F3hg19_v2_chr2_+_105471969_105471969-0.261.6e-01Click!

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_104198377 4.13 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr15_-_45670924 3.62 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr14_-_21270995 2.92 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr4_-_16085340 2.87 ENST00000508167.1
PROM1
prominin 1
chr4_-_16085314 2.86 ENST00000510224.1
PROM1
prominin 1
chr14_-_21270561 2.86 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr12_+_109785708 2.75 ENST00000310903.5
MYO1H
myosin IH
chr16_-_21314360 2.64 ENST00000219599.3
ENST00000576703.1
CRYM
crystallin, mu
chr11_-_26593649 2.44 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr11_-_26593677 2.36 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr18_-_24722995 2.14 ENST00000581714.1
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr12_+_49297899 2.03 ENST00000552942.1
ENST00000320516.4
CCDC65
coiled-coil domain containing 65
chr1_-_104238912 1.98 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr1_-_104239076 1.96 ENST00000370080.3
AMY1B
amylase, alpha 1B (salivary)
chr9_+_34458771 1.93 ENST00000437363.1
ENST00000242317.4
DNAI1
dynein, axonemal, intermediate chain 1
chr15_+_76352178 1.89 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr3_-_112565703 1.86 ENST00000488794.1
CD200R1L
CD200 receptor 1-like
chr19_-_14992264 1.65 ENST00000327462.2
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr3_-_112564797 1.65 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr1_+_104159999 1.54 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr12_+_49297887 1.47 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr10_+_695888 1.43 ENST00000441152.2
PRR26
proline rich 26
chr7_-_100026280 1.38 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr1_-_151345159 1.38 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
SELENBP1
selenium binding protein 1
chr1_+_104293028 1.36 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr15_+_71228826 1.34 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr1_+_59775752 1.28 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr3_-_58613323 1.16 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr3_+_98072698 1.05 ENST00000354924.2
OR5K4
olfactory receptor, family 5, subfamily K, member 4
chr5_+_36608422 0.99 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_100356551 0.98 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr5_+_140602904 0.97 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr8_+_67039131 0.95 ENST00000315962.4
ENST00000353317.5
TRIM55
tripartite motif containing 55
chr4_-_100356291 0.95 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr18_-_52989525 0.94 ENST00000457482.3
TCF4
transcription factor 4
chr5_-_160279207 0.93 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr18_-_52989217 0.90 ENST00000570287.2
TCF4
transcription factor 4
chr1_+_61547405 0.87 ENST00000371189.4
NFIA
nuclear factor I/A
chrX_+_130192318 0.86 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr20_-_21378666 0.85 ENST00000351817.4
NKX2-4
NK2 homeobox 4
chrX_+_41548259 0.84 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr3_-_167371740 0.82 ENST00000466760.1
ENST00000479765.1
WDR49
WD repeat domain 49
chrX_+_41548220 0.82 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr12_-_122107549 0.77 ENST00000355329.3
MORN3
MORN repeat containing 3
chr6_-_49712147 0.75 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr3_+_189507460 0.75 ENST00000434928.1
TP63
tumor protein p63
chr6_-_49712123 0.75 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr12_-_91505608 0.74 ENST00000266718.4
LUM
lumican
chrX_-_112084043 0.73 ENST00000304758.1
AMOT
angiomotin
chr5_-_42811986 0.73 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr1_+_61547894 0.72 ENST00000403491.3
NFIA
nuclear factor I/A
chr4_+_154622652 0.69 ENST00000260010.6
TLR2
toll-like receptor 2
chr12_-_25801478 0.67 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1
intermediate filament tail domain containing 1
chr5_-_42812143 0.65 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr17_+_66255310 0.64 ENST00000448504.2
ARSG
arylsulfatase G
chr1_-_179112189 0.64 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr9_+_108424738 0.63 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr21_+_25801041 0.63 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr13_-_46679185 0.63 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr7_+_116593433 0.61 ENST00000323984.3
ENST00000393449.1
ST7
suppression of tumorigenicity 7
chr13_-_46679144 0.60 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr12_-_9760482 0.60 ENST00000229402.3
KLRB1
killer cell lectin-like receptor subfamily B, member 1
chr7_+_48211048 0.60 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr6_-_134861089 0.57 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr4_+_30723003 0.56 ENST00000543491.1
PCDH7
protocadherin 7
chr22_+_40322595 0.56 ENST00000420971.1
ENST00000544756.1
GRAP2
GRB2-related adaptor protein 2
chr22_+_40322623 0.55 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr10_-_116444371 0.53 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr7_+_150065278 0.52 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr11_-_118305921 0.50 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr10_+_85933494 0.50 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr1_-_216978709 0.50 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr11_+_17316870 0.50 ENST00000458064.2
NUCB2
nucleobindin 2
chr8_-_64080945 0.50 ENST00000603538.1
YTHDF3-AS1
YTHDF3 antisense RNA 1 (head to head)
chr12_+_64173888 0.50 ENST00000537373.1
TMEM5
transmembrane protein 5
chr11_+_36616355 0.49 ENST00000532470.2
C11orf74
chromosome 11 open reading frame 74
chr7_+_100026406 0.49 ENST00000414441.1
MEPCE
methylphosphate capping enzyme
chr9_+_21967137 0.48 ENST00000441769.2
C9orf53
chromosome 9 open reading frame 53
chr4_-_110723194 0.48 ENST00000394635.3
CFI
complement factor I
chr4_-_110723134 0.48 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr4_-_110723335 0.46 ENST00000394634.2
CFI
complement factor I
chr17_+_17685422 0.45 ENST00000395774.1
RAI1
retinoic acid induced 1
chr7_+_133812052 0.45 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr14_-_25479811 0.45 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr12_-_91573132 0.44 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr20_+_43990576 0.44 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr1_+_167298281 0.43 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr15_-_49255632 0.43 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr3_-_62359180 0.43 ENST00000283268.3
FEZF2
FEZ family zinc finger 2
chr12_-_111926342 0.41 ENST00000389154.3
ATXN2
ataxin 2
chr6_-_76782371 0.41 ENST00000369950.3
ENST00000369963.3
IMPG1
interphotoreceptor matrix proteoglycan 1
chrX_-_32173579 0.40 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr7_-_105332084 0.40 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr14_+_100485712 0.40 ENST00000544450.2
EVL
Enah/Vasp-like
chr5_+_125758813 0.40 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr3_+_53528659 0.39 ENST00000350061.5
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr13_-_70682590 0.39 ENST00000377844.4
KLHL1
kelch-like family member 1
chr1_-_48866517 0.39 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr1_-_1297157 0.39 ENST00000477278.2
MXRA8
matrix-remodelling associated 8
chr3_-_52931557 0.37 ENST00000504329.1
ENST00000355083.5
TMEM110-MUSTN1
TMEM110
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chrX_+_130192216 0.37 ENST00000276211.5
ARHGAP36
Rho GTPase activating protein 36
chr1_-_67142710 0.37 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr19_-_56135928 0.37 ENST00000591479.1
ENST00000325351.4
ZNF784
zinc finger protein 784
chr3_+_125694347 0.37 ENST00000505382.1
ENST00000511082.1
ROPN1B
rhophilin associated tail protein 1B
chr17_-_5321549 0.36 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr2_-_46769694 0.36 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chrX_-_80457385 0.35 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5
high mobility group nucleosome binding domain 5
chrX_+_105855160 0.35 ENST00000372544.2
ENST00000372548.4
CXorf57
chromosome X open reading frame 57
chr6_-_154751629 0.35 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr6_+_127898312 0.34 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr13_+_28366780 0.34 ENST00000302945.2
GSX1
GS homeobox 1
chr5_-_111312622 0.33 ENST00000395634.3
NREP
neuronal regeneration related protein
chr10_-_94003003 0.33 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr5_+_125758865 0.32 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr12_-_51718436 0.32 ENST00000544402.1
BIN2
bridging integrator 2
chr1_+_244515930 0.32 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr17_-_38978847 0.31 ENST00000269576.5
KRT10
keratin 10
chr5_-_146461027 0.31 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr7_-_130080977 0.31 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr14_-_61116168 0.30 ENST00000247182.6
SIX1
SIX homeobox 1
chr1_+_28099683 0.30 ENST00000373943.4
STX12
syntaxin 12
chr3_+_12525931 0.30 ENST00000446004.1
ENST00000314571.7
ENST00000454502.2
ENST00000383797.5
ENST00000402228.3
ENST00000284995.6
ENST00000444864.1
TSEN2
TSEN2 tRNA splicing endonuclease subunit
chr5_-_160973649 0.28 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr7_+_119913688 0.28 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr12_+_58003935 0.28 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr22_-_39268308 0.28 ENST00000407418.3
CBX6
chromobox homolog 6
chr5_-_36152031 0.27 ENST00000296603.4
LMBRD2
LMBR1 domain containing 2
chr1_-_27701307 0.27 ENST00000270879.4
ENST00000354982.2
FCN3
ficolin (collagen/fibrinogen domain containing) 3
chr7_-_16505440 0.27 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr5_+_101569696 0.27 ENST00000597120.1
AC008948.1
AC008948.1
chr6_-_46459675 0.27 ENST00000306764.7
RCAN2
regulator of calcineurin 2
chr5_+_42756903 0.26 ENST00000361970.5
ENST00000388827.4
CCDC152
coiled-coil domain containing 152
chr9_-_15472730 0.26 ENST00000481862.1
PSIP1
PC4 and SFRS1 interacting protein 1
chr2_+_61372226 0.25 ENST00000426997.1
C2orf74
chromosome 2 open reading frame 74
chr6_-_2634820 0.25 ENST00000296847.3
C6orf195
chromosome 6 open reading frame 195
chr5_+_139505520 0.24 ENST00000333305.3
IGIP
IgA-inducing protein
chr7_-_38948774 0.24 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr17_-_40540377 0.24 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr15_-_75249793 0.23 ENST00000322177.5
RPP25
ribonuclease P/MRP 25kDa subunit
chr10_+_97759848 0.23 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr1_+_112016414 0.22 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr6_+_131894284 0.22 ENST00000368087.3
ENST00000356962.2
ARG1
arginase 1
chr12_-_102224704 0.21 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr5_+_140474181 0.21 ENST00000194155.4
PCDHB2
protocadherin beta 2
chr17_-_26220366 0.21 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr17_-_40540586 0.21 ENST00000264657.5
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr1_-_89664595 0.21 ENST00000355754.6
GBP4
guanylate binding protein 4
chr2_-_175711133 0.21 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr5_+_175288631 0.21 ENST00000509837.1
CPLX2
complexin 2
chr4_+_175839551 0.21 ENST00000404450.4
ENST00000514159.1
ADAM29
ADAM metallopeptidase domain 29
chr15_+_49447947 0.20 ENST00000327171.3
ENST00000560654.1
GALK2
galactokinase 2
chr3_+_148508845 0.20 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr12_-_9885888 0.20 ENST00000327839.3
CLECL1
C-type lectin-like 1
chr1_-_169703203 0.20 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr16_-_279405 0.20 ENST00000430864.1
ENST00000293872.8
ENST00000337351.4
ENST00000397783.1
LUC7L
LUC7-like (S. cerevisiae)
chr19_-_44124019 0.19 ENST00000300811.3
ZNF428
zinc finger protein 428
chr7_-_32529973 0.19 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr12_-_102224457 0.19 ENST00000549165.1
ENST00000549940.1
ENST00000392919.4
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr5_+_140762268 0.19 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr17_-_61996192 0.18 ENST00000392824.4
CSHL1
chorionic somatomammotropin hormone-like 1
chr1_-_111743285 0.18 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr12_-_39734783 0.18 ENST00000552961.1
KIF21A
kinesin family member 21A
chr12_-_7848364 0.18 ENST00000329913.3
GDF3
growth differentiation factor 3
chr11_-_57004658 0.18 ENST00000606794.1
APLNR
apelin receptor
chr20_+_277737 0.17 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr16_+_31128978 0.17 ENST00000448516.2
ENST00000219797.4
KAT8
K(lysine) acetyltransferase 8
chrM_+_5824 0.17 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr20_+_58179582 0.17 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr20_-_7921090 0.17 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr8_-_65711310 0.17 ENST00000310193.3
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr7_-_50628745 0.17 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr12_+_25205568 0.17 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr2_-_183387430 0.17 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr17_-_37844267 0.17 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
PGAP3
post-GPI attachment to proteins 3
chr5_+_96212185 0.16 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr12_-_91574142 0.16 ENST00000547937.1
DCN
decorin
chr8_+_61591337 0.16 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr22_-_43036607 0.15 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr3_-_193272874 0.15 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr1_+_207818460 0.15 ENST00000508064.2
CR1L
complement component (3b/4b) receptor 1-like
chr10_+_114710211 0.15 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr11_+_33279850 0.15 ENST00000531504.1
ENST00000456517.1
HIPK3
homeodomain interacting protein kinase 3
chr11_-_104480019 0.15 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr2_+_145780725 0.15 ENST00000451478.1
TEX41
testis expressed 41 (non-protein coding)
chr22_+_30476163 0.15 ENST00000336726.6
HORMAD2
HORMA domain containing 2
chr4_+_175839506 0.14 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM29
ADAM metallopeptidase domain 29
chr4_+_146403912 0.14 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr17_-_38821373 0.14 ENST00000394052.3
KRT222
keratin 222
chr1_+_19923454 0.14 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1
MINOS1
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr5_+_141346385 0.14 ENST00000513019.1
ENST00000356143.1
RNF14
ring finger protein 14
chr12_+_49740700 0.14 ENST00000549441.2
ENST00000395069.3
DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr1_-_247921982 0.14 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr17_-_40540484 0.14 ENST00000588969.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr12_-_56753858 0.13 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr12_-_91573316 0.13 ENST00000393155.1
DCN
decorin
chr22_+_30477000 0.13 ENST00000403975.1
HORMAD2
HORMA domain containing 2
chr17_+_3379284 0.13 ENST00000263080.2
ASPA
aspartoacylase
chr7_-_36406750 0.13 ENST00000453212.1
ENST00000415803.2
ENST00000440378.1
ENST00000431396.1
ENST00000317020.6
ENST00000436884.1
KIAA0895
KIAA0895
chr9_+_137967268 0.13 ENST00000371799.4
ENST00000277415.11
OLFM1
olfactomedin 1
chr1_+_152627927 0.13 ENST00000444515.1
ENST00000536536.1
LINC00302
long intergenic non-protein coding RNA 302

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.6 1.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 3.6 GO:0006600 creatine metabolic process(GO:0006600)
0.3 1.2 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 0.7 GO:0032289 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 1.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 2.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 1.0 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.7 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 1.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.3 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.3 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.3 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 6.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 2.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.6 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.3 GO:0019321 pentose metabolic process(GO:0019321)
0.1 4.8 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.7 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648) regulation of determination of dorsal identity(GO:2000015)
0.1 0.5 GO:0040031 snRNA modification(GO:0040031)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.7 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.7 GO:0021794 thalamus development(GO:0021794)
0.0 0.3 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.4 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421) cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 2.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:2000439 negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 3.2 GO:0007586 digestion(GO:0007586)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 1.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.4 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.5 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.0 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.0 0.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 0.7 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 1.9 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 0.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 2.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 3.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 4.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.7 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 2.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0043235 receptor complex(GO:0043235)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:0016160 amylase activity(GO:0016160)
0.8 5.8 GO:0004522 ribonuclease A activity(GO:0004522)
0.7 2.6 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.5 1.9 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.4 2.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.2 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 1.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.3 GO:0008430 selenium binding(GO:0008430)
0.1 0.7 GO:0043532 angiostatin binding(GO:0043532)
0.1 3.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 5.9 GO:0042805 actinin binding(GO:0042805)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.4 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 1.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 11.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 4.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 3.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins