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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU4F1_POU4F3

Z-value: 0.62

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Transcription factors associated with POU4F1_POU4F3

Gene Symbol Gene ID Gene Info
ENSG00000152192.6 POU class 4 homeobox 1
ENSG00000091010.4 POU class 4 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU4F1hg19_v2_chr13_-_79177673_791777010.281.4e-01Click!
POU4F3hg19_v2_chr5_+_145718587_1457186070.173.6e-01Click!

Activity profile of POU4F1_POU4F3 motif

Sorted Z-values of POU4F1_POU4F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_31488433 1.39 ENST00000455608.1
smoothelin
chr3_-_74570291 1.21 ENST00000263665.6
contactin 3 (plasmacytoma associated)
chr2_-_88285309 1.05 ENST00000420840.2
RANBP2-like and GRIP domain containing 2
chr15_-_42264702 1.03 ENST00000220325.4
EH-domain containing 4
chr2_+_182850743 0.91 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr9_-_74675521 0.86 ENST00000377024.3
chromosome 9 open reading frame 57
chr19_+_56368803 0.82 ENST00000587891.1
NLR family, pyrin domain containing 4
chr18_+_29027696 0.80 ENST00000257189.4
desmoglein 3
chr19_-_18632861 0.79 ENST00000262809.4
elongation factor RNA polymerase II
chr20_+_30102231 0.72 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
histocompatibility (minor) 13
chr2_+_87135076 0.72 ENST00000409776.2
RANBP2-like and GRIP domain containing 1
chr18_+_47088401 0.70 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial
chr14_+_22977587 0.68 ENST00000390504.1
T cell receptor alpha joining 33
chr22_+_41777927 0.67 ENST00000266304.4
thyrotrophic embryonic factor
chrX_+_65382433 0.66 ENST00000374727.3
hephaestin
chr14_-_101036119 0.65 ENST00000355173.2
brain-enriched guanylate kinase-associated
chr3_-_185826855 0.62 ENST00000306376.5
ets variant 5
chr1_+_22979474 0.61 ENST00000509305.1
complement component 1, q subcomponent, B chain
chr12_+_100750846 0.55 ENST00000323346.5
solute carrier family 17 (vesicular glutamate transporter), member 8
chrX_-_32173579 0.55 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
dystrophin
chr18_-_31803169 0.54 ENST00000590712.1
nucleolar protein 4
chr9_+_35673853 0.51 ENST00000378357.4
carbonic anhydrase IX
chr2_+_182850551 0.51 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr1_-_197036364 0.50 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr9_-_34458531 0.50 ENST00000379089.1
ENST00000379087.1
ENST00000379084.1
ENST00000379081.1
ENST00000379080.1
ENST00000422409.1
ENST00000379078.1
ENST00000445726.1
ENST00000297620.4
family with sequence similarity 219, member A
chr19_+_19639704 0.49 ENST00000514277.4
YjeF N-terminal domain containing 3
chrX_+_135279179 0.48 ENST00000370676.3
four and a half LIM domains 1
chr7_+_150725510 0.47 ENST00000461373.1
ENST00000358849.4
ENST00000297504.6
ENST00000542328.1
ENST00000498578.1
ENST00000356058.4
ENST00000477719.1
ENST00000477092.1
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr19_+_19639670 0.46 ENST00000436027.5
YjeF N-terminal domain containing 3
chr12_+_130554803 0.45 ENST00000535487.1
RP11-474D1.2
chr4_+_89513574 0.45 ENST00000402738.1
ENST00000431413.1
ENST00000422770.1
ENST00000407637.1
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chrX_+_135278908 0.45 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr12_-_89746173 0.44 ENST00000308385.6
dual specificity phosphatase 6
chr3_+_46742823 0.44 ENST00000326431.3
transmembrane inner ear
chr14_+_101297740 0.43 ENST00000555928.1
maternally expressed 3 (non-protein coding)
chr1_+_8378140 0.42 ENST00000377479.2
solute carrier family 45, member 1
chr5_+_119867159 0.41 ENST00000505123.1
proline rich 16
chr1_-_54303949 0.41 ENST00000234725.8
NDC1 transmembrane nucleoporin
chr5_-_39270725 0.40 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr8_-_125577940 0.39 ENST00000519168.1
ENST00000395508.2
metastasis suppressor 1
chr1_+_50574585 0.39 ENST00000371824.1
ENST00000371823.4
ELAV like neuron-specific RNA binding protein 4
chr14_-_65409502 0.38 ENST00000389614.5
glutathione peroxidase 2 (gastrointestinal)
chr1_-_54303934 0.38 ENST00000537333.1
NDC1 transmembrane nucleoporin
chr2_-_101034070 0.37 ENST00000264249.3
carbohydrate sulfotransferase 10
chr19_+_39138271 0.36 ENST00000252699.2
actinin, alpha 4
chr1_+_66458072 0.34 ENST00000423207.2
phosphodiesterase 4B, cAMP-specific
chr4_-_21546272 0.34 ENST00000509207.1
Kv channel interacting protein 4
chr10_+_33271469 0.34 ENST00000414157.1
RP11-462L8.1
chr22_+_30476163 0.33 ENST00000336726.6
HORMA domain containing 2
chr22_+_40322623 0.32 ENST00000399090.2
GRB2-related adaptor protein 2
chr22_+_40322595 0.32 ENST00000420971.1
ENST00000544756.1
GRB2-related adaptor protein 2
chr20_+_30555805 0.32 ENST00000562532.2
XK, Kell blood group complex subunit-related family, member 7
chr19_+_52873166 0.32 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
zinc finger protein 880
chr18_-_31803435 0.32 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
nucleolar protein 4
chr12_+_41221794 0.31 ENST00000547849.1
contactin 1
chr16_+_33204980 0.31 ENST00000561509.1
TP53 target 3C
chr9_+_75263565 0.31 ENST00000396237.3
transmembrane channel-like 1
chr15_+_74422585 0.31 ENST00000561740.1
ENST00000435464.1
ENST00000453268.2
immunoglobulin superfamily containing leucine-rich repeat 2
chr2_+_29320571 0.31 ENST00000401605.1
ENST00000401617.2
CAP-GLY domain containing linker protein family, member 4
chrX_-_65253506 0.30 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr12_+_110011571 0.30 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
mevalonate kinase
chr1_+_73771844 0.30 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
chr5_+_157158205 0.30 ENST00000231198.7
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr8_+_98900132 0.30 ENST00000520016.1
matrilin 2
chr15_+_58724184 0.29 ENST00000433326.2
lipase, hepatic
chr4_-_25032501 0.29 ENST00000382114.4
leucine-rich repeat LGI family, member 2
chr2_+_190541153 0.29 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ankyrin and armadillo repeat containing
chr19_+_48949030 0.29 ENST00000253237.5
glutamate-rich WD repeat containing 1
chr13_-_20110902 0.28 ENST00000390680.2
ENST00000382977.4
ENST00000382975.4
ENST00000457266.2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr22_-_38506619 0.27 ENST00000332536.5
ENST00000381669.3
BAI1-associated protein 2-like 2
chr2_+_190540711 0.27 ENST00000520309.1
ankyrin and armadillo repeat containing
chr4_-_68749699 0.26 ENST00000545541.1
transmembrane protease, serine 11D
chrX_-_106146547 0.26 ENST00000276173.4
ENST00000411805.1
ripply transcriptional repressor 1
chr12_+_10658201 0.26 ENST00000322446.3
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr4_+_74269956 0.26 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr19_-_20844343 0.25 ENST00000595405.1
zinc finger protein 626
chr8_+_70404996 0.25 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr13_+_52586517 0.24 ENST00000523764.1
ENST00000521508.1
ALG11, alpha-1,2-mannosyltransferase
chr5_-_41261540 0.23 ENST00000263413.3
complement component 6
chr6_+_34204642 0.23 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr14_-_65409438 0.23 ENST00000557049.1
glutathione peroxidase 2 (gastrointestinal)
chr19_-_51141196 0.23 ENST00000338916.4
synaptotagmin III
chr17_-_36358166 0.23 ENST00000537432.1
TBC1 domain family, member 3
chr11_+_35211429 0.23 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44 molecule (Indian blood group)
chr2_+_87144738 0.22 ENST00000559485.1
RANBP2-like and GRIP domain containing 1
chr3_-_33686925 0.22 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
cytoplasmic linker associated protein 2
chr6_-_127840453 0.22 ENST00000556132.1
SOGA family member 3
chr19_+_39138320 0.22 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
actinin, alpha 4
chr4_-_103998439 0.22 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr6_-_27880174 0.22 ENST00000303324.2
olfactory receptor, family 2, subfamily B, member 2
chr12_+_10658489 0.21 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr5_+_139739772 0.21 ENST00000506757.2
ENST00000230993.6
ENST00000506545.1
ENST00000432095.2
ENST00000507527.1
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr7_-_100026280 0.21 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr5_-_11588907 0.21 ENST00000513598.1
ENST00000503622.1
catenin (cadherin-associated protein), delta 2
chr7_+_134528635 0.20 ENST00000445569.2
caldesmon 1
chr5_-_77844974 0.20 ENST00000515007.2
lipoma HMGIC fusion partner-like 2
chr6_-_127840336 0.20 ENST00000525778.1
SOGA family member 3
chr22_-_30970560 0.20 ENST00000402369.1
ENST00000406361.1
galactose-3-O-sulfotransferase 1
chr2_-_183387064 0.19 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr4_-_122744998 0.19 ENST00000274026.5
cyclin A2
chr14_+_24407940 0.19 ENST00000354854.1
DHRS4-AS1
chr22_+_39101728 0.19 ENST00000216044.5
ENST00000484657.1
GTP binding protein 1
chr1_+_63063152 0.19 ENST00000371129.3
angiopoietin-like 3
chr2_+_204732487 0.19 ENST00000302823.3
cytotoxic T-lymphocyte-associated protein 4
chr5_-_134871639 0.19 ENST00000314744.4
neurogenin 1
chr3_+_68055366 0.18 ENST00000496687.1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr4_-_152149033 0.18 ENST00000514152.1
SH3 domain containing 19
chrX_+_41583408 0.18 ENST00000302548.4
G protein-coupled receptor 82
chr10_-_128359074 0.18 ENST00000544758.1
chromosome 10 open reading frame 90
chr20_+_30063067 0.18 ENST00000201979.2
RAS (RAD and GEM)-like GTP-binding 1
chr1_+_59775752 0.17 ENST00000371212.1
FGGY carbohydrate kinase domain containing
chr20_-_23731893 0.16 ENST00000398402.1
cystatin SN
chr16_+_6533380 0.16 ENST00000552089.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr6_-_76782371 0.16 ENST00000369950.3
ENST00000369963.3
interphotoreceptor matrix proteoglycan 1
chr5_-_135290705 0.16 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr6_-_127840021 0.16 ENST00000465909.2
SOGA family member 3
chr2_+_29336855 0.15 ENST00000404424.1
CAP-GLY domain containing linker protein family, member 4
chr1_+_206808918 0.15 ENST00000367108.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr17_-_29641084 0.15 ENST00000544462.1
ecotropic viral integration site 2B
chr5_-_11589131 0.15 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chr9_-_95298314 0.15 ENST00000344604.5
ENST00000375540.1
extracellular matrix protein 2, female organ and adipocyte specific
chr22_+_30477000 0.15 ENST00000403975.1
HORMA domain containing 2
chr6_-_10115007 0.14 ENST00000485268.1
orofacial cleft 1 candidate 1
chr7_-_64023410 0.14 ENST00000447137.2
zinc finger protein 680
chr13_-_46756351 0.14 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_161691353 0.14 ENST00000367948.2
Fc receptor-like B
chr12_+_54366894 0.14 ENST00000546378.1
ENST00000243082.4
homeobox C11
chr1_+_145292806 0.14 ENST00000448873.2
neuroblastoma breakpoint family, member 10
chr4_+_106631966 0.14 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr3_-_52860850 0.14 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr9_-_3469181 0.14 ENST00000366116.2
Uncharacterized protein
chr8_+_52730143 0.14 ENST00000415643.1
Uncharacterized protein
chr1_+_67773044 0.13 ENST00000262345.1
ENST00000371000.1
interleukin 12 receptor, beta 2
chr6_-_116833500 0.13 ENST00000356128.4
trafficking protein particle complex 3-like
chr1_+_206808868 0.13 ENST00000367109.2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr16_-_85784557 0.13 ENST00000602675.1
chromosome 16 open reading frame 74
chr20_-_33872548 0.13 ENST00000374443.3
eukaryotic translation initiation factor 6
chr14_-_107049312 0.13 ENST00000390627.2
immunoglobulin heavy variable 3-53
chr9_-_4666421 0.13 ENST00000381895.5
spermatogenesis associated 6-like
chr11_-_35441597 0.13 ENST00000395753.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr17_+_29664830 0.13 ENST00000444181.2
ENST00000417592.2
neurofibromin 1
chr14_-_106668095 0.13 ENST00000390606.2
immunoglobulin heavy variable 3-20
chr8_+_70850403 0.13 ENST00000602248.1
Uncharacterized protein
chr12_-_10978957 0.12 ENST00000240619.2
taste receptor, type 2, member 10
chr14_-_54908043 0.12 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr11_-_83393429 0.12 ENST00000426717.2
discs, large homolog 2 (Drosophila)
chr18_+_28956740 0.12 ENST00000308128.4
ENST00000359747.4
desmoglein 4
chr10_-_11574274 0.12 ENST00000277575.5
USP6 N-terminal like
chr2_+_185463093 0.12 ENST00000302277.6
zinc finger protein 804A
chr12_-_58212487 0.12 ENST00000549994.1
advillin
chr12_-_91546926 0.12 ENST00000550758.1
decorin
chr7_-_20256965 0.12 ENST00000400331.5
ENST00000332878.4
metastasis associated in colon cancer 1
chr1_+_198608146 0.11 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr2_-_183387430 0.11 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr16_-_67217844 0.11 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895-like
chr9_-_21166659 0.11 ENST00000380225.1
interferon, alpha 21
chr2_+_65663812 0.11 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
chr6_-_136847099 0.11 ENST00000438100.2
microtubule-associated protein 7
chr2_-_183387283 0.11 ENST00000435564.1
phosphodiesterase 1A, calmodulin-dependent
chr21_-_31852663 0.11 ENST00000390689.2
keratin associated protein 19-1
chrX_-_138724994 0.11 ENST00000536274.1
MCF.2 cell line derived transforming sequence
chr1_-_33430286 0.10 ENST00000373456.7
ENST00000356990.5
ENST00000235150.4
ring finger protein 19B
chr1_+_160336851 0.10 ENST00000302101.5
nescient helix loop helix 1
chr22_+_39348723 0.10 ENST00000402255.1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr9_+_131683174 0.10 ENST00000372592.3
ENST00000428610.1
phytanoyl-CoA dioxygenase domain containing 1
chr12_-_91574142 0.10 ENST00000547937.1
decorin
chr17_+_17685422 0.10 ENST00000395774.1
retinoic acid induced 1
chr4_+_37962018 0.09 ENST00000504686.1
pituitary tumor-transforming 2
chr11_-_26593677 0.09 ENST00000527569.1
mucin 15, cell surface associated
chr10_+_81891416 0.09 ENST00000372270.2
placenta-specific 9
chr11_+_44117099 0.09 ENST00000533608.1
exostosin glycosyltransferase 2
chr2_-_183106641 0.09 ENST00000346717.4
phosphodiesterase 1A, calmodulin-dependent
chr5_+_140767452 0.09 ENST00000519479.1
protocadherin gamma subfamily B, 4
chr3_-_196242233 0.09 ENST00000397537.2
single-pass membrane protein with coiled-coil domains 1
chr8_-_110986918 0.09 ENST00000297404.1
potassium channel, subfamily V, member 1
chr12_-_51611477 0.09 ENST00000389243.4
POU class 6 homeobox 1
chr8_-_52721975 0.09 ENST00000356297.4
ENST00000543296.1
peroxidasin homolog (Drosophila)-like
chr21_-_37914898 0.09 ENST00000399136.1
claudin 14
chr18_+_32397918 0.09 ENST00000590727.1
ENST00000601125.1
dystrobrevin, alpha
chr2_+_197577841 0.08 ENST00000409270.1
coiled-coil domain containing 150
chr10_+_90346519 0.08 ENST00000371939.3
lipase, family member J
chr6_+_127898312 0.08 ENST00000329722.7
chromosome 6 open reading frame 58
chr3_-_149375783 0.08 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WW domain containing transcription regulator 1
chr5_-_59481406 0.08 ENST00000546160.1
phosphodiesterase 4D, cAMP-specific
chr11_-_35441524 0.08 ENST00000395750.1
ENST00000449068.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_-_136847610 0.08 ENST00000454590.1
ENST00000432797.2
microtubule-associated protein 7
chr2_+_133874577 0.08 ENST00000596384.1
HCG2006742; Protein LOC100996685
chr5_+_112227311 0.07 ENST00000391338.1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr5_-_132200477 0.07 ENST00000296875.2
growth differentiation factor 9
chrX_+_72062802 0.07 ENST00000373533.1
DMRT-like family C1B
chrX_-_72097698 0.07 ENST00000373530.1
DMRT-like family C1
chr14_+_31494672 0.07 ENST00000542754.2
ENST00000313566.6
adaptor-related protein complex 4, sigma 1 subunit
chr13_-_103346854 0.07 ENST00000267273.6
methyltransferase like 21C
chr18_+_61575200 0.07 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr14_+_31494841 0.07 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
adaptor-related protein complex 4, sigma 1 subunit
chr3_+_160939050 0.07 ENST00000493066.1
ENST00000351193.2
ENST00000472947.1
ENST00000463518.1
NMD3 ribosome export adaptor
chr17_+_45728427 0.07 ENST00000540627.1
karyopherin (importin) beta 1
chr9_-_4666337 0.06 ENST00000381890.5
spermatogenesis associated 6-like
chr18_-_24443151 0.06 ENST00000440832.3
aquaporin 4
chrX_+_47053208 0.06 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
ubiquitin-like modifier activating enzyme 1

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F1_POU4F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2 0.8 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 0.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 0.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.4 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 2.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.5 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 0.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.0 GO:0006907 pinocytosis(GO:0006907)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 1.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 1.0 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 1.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:1903970 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.2 0.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.7 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.6 GO:0005602 complement component C1 complex(GO:0005602)
0.1 0.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.6 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 1.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.8 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects