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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU6F2

Z-value: 0.72

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Transcription factors associated with POU6F2

Gene Symbol Gene ID Gene Info
POU6F2
ENSG00000106536.15 POU class 6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU6F2hg19_v2_chr7_+_39125365_39125489,
hg19_v2_chr7_+_39017504_39017598		0.242.0e-01Click!

Activity profile of POU6F2 motif

Sorted Z-values of POU6F2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_151646800 2.36 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr12_-_30887948 2.17 ENST00000433722.2
CAPRIN2
caprin family member 2
chr2_+_128403720 2.01 ENST00000272644.3
GPR17
G protein-coupled receptor 17
chr2_+_128403439 1.96 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr5_-_139726181 1.48 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr10_+_94352956 1.38 ENST00000260731.3
KIF11
kinesin family member 11
chr3_-_33686925 1.36 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr14_+_32798547 1.33 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr1_-_182641367 1.27 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr12_+_15699286 1.26 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr12_-_87232644 1.26 ENST00000549405.2
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr14_+_32798462 1.21 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr12_-_89746173 1.12 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr3_+_159557637 1.04 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr2_-_216003127 1.04 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr22_+_30792846 1.02 ENST00000312932.9
ENST00000428195.1
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr2_-_69098566 1.00 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr1_-_208417620 0.89 ENST00000367033.3
PLXNA2
plexin A2
chr1_-_153123345 0.89 ENST00000368748.4
SPRR2G
small proline-rich protein 2G
chr14_-_69261310 0.86 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr6_-_32157947 0.79 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr10_+_120967072 0.77 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr7_-_83824169 0.72 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_-_156486120 0.66 ENST00000522693.1
HAVCR1
hepatitis A virus cellular receptor 1
chr8_+_22424551 0.65 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr21_-_31864275 0.63 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr3_+_111717600 0.61 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111718036 0.61 ENST00000455401.2
TAGLN3
transgelin 3
chr17_-_39553844 0.61 ENST00000251645.2
KRT31
keratin 31
chr3_-_33686743 0.61 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr6_-_87804815 0.58 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr17_-_19290483 0.58 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr10_+_77056134 0.57 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1
ZNF503 antisense RNA 1
chr4_+_66536248 0.57 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr3_+_111717511 0.57 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr17_-_19290117 0.56 ENST00000497081.2
MFAP4
microfibrillar-associated protein 4
chr6_+_25754927 0.54 ENST00000377905.4
ENST00000439485.2
SLC17A4
solute carrier family 17, member 4
chr8_+_39792474 0.53 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chr6_+_130339710 0.49 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chrX_+_43515467 0.49 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chrX_-_106243451 0.48 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr13_+_78315466 0.47 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr17_-_48133054 0.46 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr6_+_29274403 0.45 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr7_-_80141328 0.44 ENST00000398291.3
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr2_-_105030466 0.43 ENST00000449772.1
AC068535.3
AC068535.3
chr1_+_107683436 0.42 ENST00000370068.1
NTNG1
netrin G1
chr14_+_39583427 0.41 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2
gem (nuclear organelle) associated protein 2
chr3_+_111718173 0.41 ENST00000494932.1
TAGLN3
transgelin 3
chr20_+_56136136 0.41 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr17_-_33390667 0.41 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr4_-_74486109 0.39 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_+_107683644 0.39 ENST00000370067.1
NTNG1
netrin G1
chr15_+_93443419 0.39 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr11_+_125034586 0.39 ENST00000298282.9
PKNOX2
PBX/knotted 1 homeobox 2
chr11_-_5364809 0.38 ENST00000300773.2
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr3_+_189507523 0.38 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr18_+_44812072 0.36 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
CTD-2130O13.1
chr1_-_193028426 0.36 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr7_+_6655225 0.35 ENST00000457543.3
ZNF853
zinc finger protein 853
chr10_-_23633720 0.35 ENST00000323327.4
C10orf67
chromosome 10 open reading frame 67
chr12_-_53045948 0.35 ENST00000309680.3
KRT2
keratin 2
chr22_-_32767017 0.34 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr4_-_164395014 0.34 ENST00000280605.3
TKTL2
transketolase-like 2
chr7_+_141478242 0.33 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr17_-_27418537 0.32 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr2_-_70780572 0.32 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr8_-_10512569 0.32 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr11_+_128563652 0.32 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr4_-_74486347 0.31 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr11_-_71823266 0.31 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chrX_+_107288239 0.31 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr12_-_16761007 0.31 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_50574585 0.30 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chrX_+_107288197 0.30 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr1_-_193028632 0.29 ENST00000421683.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr4_+_78829479 0.29 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr13_+_98612446 0.29 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
IPO5
importin 5
chr11_-_71823715 0.27 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr4_+_110749143 0.27 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr15_-_74421477 0.26 ENST00000514871.1
RP11-247C2.2
HCG2004779; Uncharacterized protein
chr4_-_74486217 0.26 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr10_-_92681033 0.26 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr11_+_31531291 0.26 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr1_-_193028621 0.25 ENST00000367455.4
ENST00000367454.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr4_-_22444733 0.25 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr3_-_57199397 0.25 ENST00000296318.7
IL17RD
interleukin 17 receptor D
chr12_-_71031185 0.25 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr17_-_39471947 0.25 ENST00000334202.3
KRTAP17-1
keratin associated protein 17-1
chr5_+_115177178 0.24 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr3_-_101039402 0.24 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr2_-_158300556 0.24 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr3_-_51909600 0.23 ENST00000446461.1
IQCF5
IQ motif containing F5
chr5_-_140998616 0.23 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chrX_+_10031499 0.22 ENST00000454666.1
WWC3
WWC family member 3
chr11_-_71823796 0.22 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr17_+_37784749 0.22 ENST00000394265.1
ENST00000394267.2
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr6_-_155635583 0.22 ENST00000367166.4
TFB1M
transcription factor B1, mitochondrial
chr1_+_175036966 0.21 ENST00000239462.4
TNN
tenascin N
chr1_+_10271674 0.21 ENST00000377086.1
KIF1B
kinesin family member 1B
chr3_+_141106458 0.21 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr3_+_189507432 0.20 ENST00000354600.5
TP63
tumor protein p63
chr13_+_58206655 0.20 ENST00000377918.3
PCDH17
protocadherin 17
chr8_+_26150628 0.20 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr5_-_36301984 0.20 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr11_-_36619771 0.20 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2
recombination activating gene 2
chr12_-_52946923 0.19 ENST00000267119.5
KRT71
keratin 71
chr13_-_103719196 0.18 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr15_+_58702742 0.18 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr6_-_89927151 0.17 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr5_-_140998481 0.17 ENST00000518047.1
DIAPH1
diaphanous-related formin 1
chr21_-_42219065 0.17 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr1_-_2458026 0.17 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chrX_+_99839799 0.17 ENST00000373031.4
TNMD
tenomodulin
chr7_+_115862858 0.16 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr12_+_54348618 0.16 ENST00000243103.3
HOXC12
homeobox C12
chr2_-_217559517 0.15 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr7_-_14028488 0.15 ENST00000405358.4
ETV1
ets variant 1
chr7_-_14029283 0.14 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr17_-_40337470 0.14 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr1_+_50571949 0.14 ENST00000357083.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chrX_-_23926004 0.13 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr2_-_182545603 0.13 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr9_+_109625378 0.09 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chrX_-_18690210 0.09 ENST00000379984.3
RS1
retinoschisin 1
chr10_-_128210005 0.09 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
C10orf90
chromosome 10 open reading frame 90
chr4_+_40198527 0.09 ENST00000381799.5
RHOH
ras homolog family member H
chr9_-_13165457 0.09 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr11_-_70672645 0.08 ENST00000423696.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr4_+_175204818 0.08 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr13_+_46039037 0.07 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr6_-_33160231 0.07 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr1_-_47655686 0.07 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr11_-_31531121 0.07 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr3_+_141105705 0.07 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr3_+_77088989 0.07 ENST00000461745.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chrX_-_21676442 0.07 ENST00000379499.2
KLHL34
kelch-like family member 34
chr21_-_31869451 0.06 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chrX_+_68835911 0.06 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr5_+_126984710 0.06 ENST00000379445.3
CTXN3
cortexin 3
chr1_+_31883048 0.06 ENST00000536859.1
SERINC2
serine incorporator 2
chr17_-_29624343 0.06 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr1_-_201140673 0.06 ENST00000367333.2
TMEM9
transmembrane protein 9
chr15_+_75080883 0.06 ENST00000567571.1
CSK
c-src tyrosine kinase
chr4_+_88571429 0.05 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chrX_-_30877837 0.05 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr7_-_19184929 0.05 ENST00000275461.3
FERD3L
Fer3-like bHLH transcription factor
chr9_-_21482312 0.05 ENST00000448696.3
IFNE
interferon, epsilon
chr10_+_18549645 0.04 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr19_-_7698599 0.04 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr18_-_13915530 0.04 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr4_+_78432907 0.03 ENST00000286758.4
CXCL13
chemokine (C-X-C motif) ligand 13
chrX_+_86772707 0.03 ENST00000373119.4
KLHL4
kelch-like family member 4
chr12_+_28410128 0.02 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr19_-_7697857 0.02 ENST00000598935.1
PCP2
Purkinje cell protein 2
chr11_-_63439013 0.02 ENST00000398868.3
ATL3
atlastin GTPase 3
chr12_+_54332535 0.02 ENST00000243056.3
HOXC13
homeobox C13
chr20_+_42187608 0.02 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr10_+_35484793 0.01 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr10_-_102989551 0.01 ENST00000370193.2
LBX1
ladybird homeobox 1
chr1_-_149900122 0.01 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr15_+_80351977 0.01 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr8_+_77593474 0.01 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr7_+_148287657 0.01 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr8_+_77593448 0.00 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr1_-_182640988 0.00 ENST00000367556.1
RGS8
regulator of G-protein signaling 8

Network of associatons between targets according to the STRING database.

First level regulatory network of POU6F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.4 1.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4 1.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.3 1.5 GO:0051541 elastin metabolic process(GO:0051541)
0.3 0.9 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.3 1.0 GO:0035627 ceramide transport(GO:0035627)
0.2 4.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2 2.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 2.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.7 GO:0048880 sensory system development(GO:0048880)
0.1 1.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.6 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.9 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 2.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 1.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.2 GO:1904647 response to rotenone(GO:1904647)
0.1 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.9 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.8 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.5 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.4 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 1.0 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 2.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.1 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.5 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.3 GO:0016328 lateral plasma membrane(GO:0016328)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 1.0 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.3 0.8 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.3 1.0 GO:0008431 vitamin E binding(GO:0008431)
0.2 1.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.4 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 4.0 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 1.0 GO:0031433 telethonin binding(GO:0031433)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 1.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.9 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction