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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PRDM1

Z-value: 0.58

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Transcription factors associated with PRDM1

Gene Symbol Gene ID Gene Info
PRDM1
ENSG00000057657.10 PR/SET domain 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM1hg19_v2_chr6_+_106534192_106534224-0.451.2e-02Click!

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_29527702 3.82 ENST00000377050.4
UBD
ubiquitin D
chr6_+_32821924 1.50 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr8_+_39770803 1.39 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr17_+_41158742 1.21 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr2_+_231191875 1.20 ENST00000444636.1
ENST00000415673.2
ENST00000243810.6
ENST00000396563.4
SP140L
SP140 nuclear body protein-like
chr11_-_47736896 1.11 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2
ATP/GTP binding protein-like 2
chr8_-_54436491 1.09 ENST00000426023.1
RP11-400K9.4
RP11-400K9.4
chr12_+_6561190 1.03 ENST00000544021.1
ENST00000266556.7
TAPBPL
TAP binding protein-like
chr15_+_71184931 1.02 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr22_-_36556821 1.00 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr15_+_71185148 0.98 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr5_-_96143796 0.92 ENST00000296754.3
ERAP1
endoplasmic reticulum aminopeptidase 1
chr1_+_212782012 0.89 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr16_-_67970990 0.87 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr3_-_49851313 0.86 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr4_-_46996424 0.84 ENST00000264318.3
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr16_+_50775948 0.82 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr10_+_91589309 0.78 ENST00000448490.1
LINC00865
long intergenic non-protein coding RNA 865
chr3_+_69915385 0.77 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr7_-_122526499 0.77 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr2_+_69240302 0.69 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr10_+_91589261 0.67 ENST00000448963.1
LINC00865
long intergenic non-protein coding RNA 865
chr8_-_23540402 0.65 ENST00000523261.1
ENST00000380871.4
NKX3-1
NK3 homeobox 1
chr15_-_37393406 0.65 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr16_+_50775971 0.61 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr14_-_21490417 0.58 ENST00000556366.1
NDRG2
NDRG family member 2
chr11_-_72432950 0.57 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr6_+_32811885 0.57 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr14_-_21490958 0.55 ENST00000554104.1
NDRG2
NDRG family member 2
chr19_+_13106383 0.54 ENST00000397661.2
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr12_+_51318513 0.54 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr8_-_29120580 0.51 ENST00000524189.1
KIF13B
kinesin family member 13B
chr14_-_21490653 0.51 ENST00000449431.2
NDRG2
NDRG family member 2
chr9_-_117568365 0.47 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr3_-_114343039 0.45 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr14_-_21490590 0.45 ENST00000557633.1
NDRG2
NDRG family member 2
chr17_+_6659153 0.45 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr6_+_32811861 0.45 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr16_+_50776021 0.44 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr17_-_43339474 0.44 ENST00000331780.4
SPATA32
spermatogenesis associated 32
chr13_+_24144796 0.44 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chrX_+_10124977 0.43 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr6_-_154831779 0.43 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr5_+_76506706 0.42 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr17_-_43339453 0.41 ENST00000543122.1
SPATA32
spermatogenesis associated 32
chr13_+_24144509 0.41 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr18_-_53070913 0.38 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr2_+_234545148 0.38 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr4_+_146403912 0.37 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr11_+_64323428 0.36 ENST00000377581.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr5_+_92919043 0.36 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_-_111746966 0.36 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr1_-_217250231 0.36 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr9_+_84304628 0.35 ENST00000437181.1
RP11-154D17.1
RP11-154D17.1
chr7_+_134832808 0.35 ENST00000275767.3
TMEM140
transmembrane protein 140
chr1_+_2985726 0.34 ENST00000511072.1
ENST00000378398.3
ENST00000441472.2
ENST00000442529.2
PRDM16
PR domain containing 16
chr2_-_231084820 0.34 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr5_-_94417339 0.34 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr19_+_49977818 0.33 ENST00000594009.1
ENST00000595510.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr17_-_56606639 0.33 ENST00000579371.1
SEPT4
septin 4
chr17_-_26694979 0.33 ENST00000438614.1
VTN
vitronectin
chr6_-_167275991 0.33 ENST00000510118.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_-_56606705 0.32 ENST00000317268.3
SEPT4
septin 4
chr6_-_32811771 0.32 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr17_-_56606664 0.32 ENST00000580844.1
SEPT4
septin 4
chr17_-_26695013 0.32 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr22_-_31688381 0.31 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr14_+_24605389 0.31 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr11_+_71710648 0.31 ENST00000260049.5
IL18BP
interleukin 18 binding protein
chr3_+_185046676 0.30 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr2_+_231280954 0.29 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen
chr11_+_71709938 0.29 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
IL18BP
interleukin 18 binding protein
chr8_+_96145974 0.28 ENST00000315367.3
PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr7_-_105332084 0.27 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr10_-_112678692 0.27 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr1_-_182361327 0.27 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chr2_-_231084617 0.27 ENST00000409815.2
SP110
SP110 nuclear body protein
chr14_+_24605361 0.27 ENST00000206451.6
ENST00000559123.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr3_-_168864427 0.26 ENST00000468789.1
MECOM
MDS1 and EVI1 complex locus
chr3_+_158362299 0.26 ENST00000478576.1
ENST00000264263.5
ENST00000464732.1
GFM1
G elongation factor, mitochondrial 1
chr7_-_86849025 0.26 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr6_-_33282163 0.26 ENST00000434618.2
ENST00000456592.2
TAPBP
TAP binding protein (tapasin)
chr5_+_112227311 0.26 ENST00000391338.1
ZRSR1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr5_+_73109339 0.25 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr6_-_33281979 0.25 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr11_+_71710973 0.25 ENST00000393707.4
IL18BP
interleukin 18 binding protein
chr5_-_93447333 0.25 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr2_-_209010874 0.24 ENST00000260988.4
CRYGB
crystallin, gamma B
chr14_-_24615805 0.24 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr10_+_22610124 0.24 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr15_-_37392086 0.23 ENST00000561208.1
MEIS2
Meis homeobox 2
chr22_-_31688431 0.23 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr9_-_69229650 0.23 ENST00000416428.1
CBWD6
COBW domain containing 6
chr2_+_69240415 0.23 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr1_-_182360918 0.23 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr1_+_2985760 0.22 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chr5_+_17444119 0.22 ENST00000503267.1
ENST00000504998.1
RP11-321E2.4
RP11-321E2.4
chr21_+_43933946 0.22 ENST00000352133.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr20_+_30946106 0.21 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr2_+_145780725 0.21 ENST00000451478.1
TEX41
testis expressed 41 (non-protein coding)
chr11_-_796197 0.21 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr2_+_231280908 0.20 ENST00000427101.2
ENST00000432979.1
SP100
SP100 nuclear antigen
chr20_+_13976015 0.20 ENST00000217246.4
MACROD2
MACRO domain containing 2
chr20_+_388791 0.20 ENST00000441733.1
ENST00000353660.3
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr4_-_54457783 0.20 ENST00000263925.7
ENST00000512247.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr11_-_96076334 0.19 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr16_-_3930724 0.19 ENST00000262367.5
CREBBP
CREB binding protein
chr1_+_110453109 0.19 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr11_+_46402583 0.18 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr6_-_121655552 0.18 ENST00000275159.6
TBC1D32
TBC1 domain family, member 32
chr2_+_179184955 0.18 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr6_-_28220002 0.18 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr11_+_46402482 0.18 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr16_+_31085714 0.17 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr11_+_46402297 0.17 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr11_+_64008443 0.17 ENST00000309366.4
FKBP2
FK506 binding protein 2, 13kDa
chr2_+_145780767 0.17 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr1_+_156737292 0.17 ENST00000271526.4
ENST00000353233.3
PRCC
papillary renal cell carcinoma (translocation-associated)
chr3_-_46000064 0.17 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr6_+_105404899 0.17 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr20_-_57089934 0.17 ENST00000439429.1
ENST00000371149.3
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr4_-_74088800 0.17 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr2_-_175260368 0.17 ENST00000342016.3
ENST00000362053.5
CIR1
corepressor interacting with RBPJ, 1
chr19_-_17186229 0.16 ENST00000253669.5
ENST00000448593.2
HAUS8
HAUS augmin-like complex, subunit 8
chr13_-_95364389 0.16 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr12_-_57505121 0.16 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr11_+_64008525 0.15 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr14_-_24615523 0.15 ENST00000559056.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr21_+_17909594 0.15 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr6_-_137113604 0.14 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr16_-_31085514 0.14 ENST00000300849.4
ZNF668
zinc finger protein 668
chrX_-_118827113 0.14 ENST00000394617.2
SEPT6
septin 6
chr9_-_34710066 0.14 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chrX_-_154563889 0.14 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr13_+_108921977 0.13 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr6_-_167276033 0.13 ENST00000503859.1
ENST00000506565.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_33282024 0.13 ENST00000475304.1
ENST00000489157.1
TAPBP
TAP binding protein (tapasin)
chr7_-_3083573 0.12 ENST00000396946.4
CARD11
caspase recruitment domain family, member 11
chr17_+_7465216 0.12 ENST00000321337.7
SENP3
SUMO1/sentrin/SMT3 specific peptidase 3
chr17_+_57232690 0.12 ENST00000262293.4
PRR11
proline rich 11
chr3_+_107241783 0.11 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chrX_-_118826784 0.10 ENST00000394616.4
SEPT6
septin 6
chr22_+_41697520 0.10 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr6_+_146348810 0.09 ENST00000492807.2
GRM1
glutamate receptor, metabotropic 1
chr2_+_234545092 0.09 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr1_-_153919128 0.09 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr3_+_107241882 0.08 ENST00000416476.2
BBX
bobby sox homolog (Drosophila)
chr16_+_30675654 0.08 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr4_-_111558135 0.08 ENST00000394598.2
ENST00000394595.3
PITX2
paired-like homeodomain 2
chr1_-_205326022 0.07 ENST00000367155.3
KLHDC8A
kelch domain containing 8A
chr20_-_18774614 0.07 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr1_+_215747118 0.07 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr1_-_205326161 0.07 ENST00000367156.3
ENST00000606887.1
ENST00000607173.1
KLHDC8A
kelch domain containing 8A
chr11_+_46402744 0.06 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr6_+_146348782 0.06 ENST00000361719.2
ENST00000392299.2
GRM1
glutamate receptor, metabotropic 1
chr2_+_145780739 0.06 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr10_-_82049424 0.06 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr4_-_146859787 0.06 ENST00000508784.1
ZNF827
zinc finger protein 827
chr1_+_28099683 0.06 ENST00000373943.4
STX12
syntaxin 12
chrX_-_118827333 0.06 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
SEPT6
septin 6
chr1_-_221915418 0.05 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr12_+_25205446 0.05 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr10_-_21661870 0.05 ENST00000433460.1
RP11-275N1.1
RP11-275N1.1
chr2_-_231084659 0.04 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr7_-_31380502 0.04 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr2_+_234526272 0.04 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr8_-_9009079 0.04 ENST00000519699.1
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr10_-_35104185 0.04 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr12_-_50561075 0.04 ENST00000422340.2
ENST00000317551.6
CERS5
ceramide synthase 5
chr2_+_234590556 0.04 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr15_+_85144217 0.04 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr12_-_120763739 0.04 ENST00000549767.1
PLA2G1B
phospholipase A2, group IB (pancreas)
chr18_-_47017956 0.04 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr15_+_75491213 0.03 ENST00000360639.2
C15orf39
chromosome 15 open reading frame 39
chr21_-_35899113 0.03 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr6_-_132910877 0.03 ENST00000258034.2
TAAR5
trace amine associated receptor 5
chr13_+_108922228 0.03 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr8_-_56986768 0.03 ENST00000523936.1
RPS20
ribosomal protein S20
chr12_+_94656297 0.02 ENST00000545312.1
PLXNC1
plexin C1
chr4_+_186990298 0.02 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr12_+_94542459 0.02 ENST00000258526.4
PLXNC1
plexin C1
chrX_-_139015153 0.02 ENST00000370557.1
ATP11C
ATPase, class VI, type 11C
chr2_+_175260451 0.02 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3
secernin 3
chr1_-_205325850 0.02 ENST00000537168.1
KLHDC8A
kelch domain containing 8A
chr3_-_167452298 0.02 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chr6_-_41909191 0.02 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr1_-_44497024 0.01 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr13_+_102104980 0.01 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr4_+_152020736 0.01 ENST00000509736.1
ENST00000505243.1
ENST00000514682.1
ENST00000322686.6
ENST00000503002.1
RPS3A
ribosomal protein S3A
chr19_+_24009879 0.01 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr2_+_135676381 0.01 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
CCNT2
cyclin T2
chr1_+_151372010 0.00 ENST00000290541.6
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr11_-_40315640 0.00 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr20_+_57226841 0.00 ENST00000358029.4
ENST00000361830.3
STX16
syntaxin 16
chr3_+_47422485 0.00 ENST00000431726.1
ENST00000456221.1
ENST00000265562.4
PTPN23
protein tyrosine phosphatase, non-receptor type 23

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0070842 aggresome assembly(GO:0070842)
0.6 1.9 GO:1990108 protein linear deubiquitination(GO:1990108)
0.3 1.4 GO:0036269 swimming behavior(GO:0036269)
0.3 1.0 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.3 0.9 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.3 0.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 1.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.2 0.6 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.2 1.0 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 2.1 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.7 GO:2000834 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.1 0.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.6 GO:0030421 defecation(GO:0030421)
0.1 0.8 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.8 GO:2001023 regulation of response to drug(GO:2001023)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.7 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.5 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 4.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.8 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.7 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.9 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 0.9 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.0 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.3 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 1.0 GO:0097227 sperm annulus(GO:0097227)
0.1 4.4 GO:0016235 aggresome(GO:0016235)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 1.9 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.9 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.5 GO:0097386 glial cell projection(GO:0097386)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 1.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.3 0.8 GO:0042007 interleukin-18 binding(GO:0042007)
0.2 0.9 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.2 3.8 GO:0070628 proteasome binding(GO:0070628)
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.9 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.5 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.7 GO:0004882 androgen receptor activity(GO:0004882)
0.1 3.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.8 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 2.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets