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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PRDM4

Z-value: 0.21

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Transcription factors associated with PRDM4

Gene Symbol Gene ID Gene Info
PRDM4
ENSG00000110851.7 PR/SET domain 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM4hg19_v2_chr12_-_108154925_108154945-0.364.9e-02Click!

Activity profile of PRDM4 motif

Sorted Z-values of PRDM4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_105953204 0.86 ENST00000409393.2
CRIP1
cysteine-rich protein 1 (intestinal)
chr14_+_105953246 0.85 ENST00000392531.3
CRIP1
cysteine-rich protein 1 (intestinal)
chr5_-_61031495 0.36 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chr9_-_127263265 0.30 ENST00000373587.3
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr1_+_54359854 0.22 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
DIO1
deiodinase, iodothyronine, type I
chr5_+_140261703 0.21 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr20_+_30555805 0.16 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr22_-_50050986 0.14 ENST00000405854.1
C22orf34
chromosome 22 open reading frame 34
chr19_-_35264089 0.14 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
ZNF599
zinc finger protein 599
chr15_+_45315302 0.13 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr3_+_16926441 0.13 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr17_+_42634844 0.12 ENST00000315323.3
FZD2
frizzled family receptor 2
chr9_+_96338647 0.12 ENST00000359246.4
PHF2
PHD finger protein 2
chr5_-_180688105 0.12 ENST00000327767.4
TRIM52
tripartite motif containing 52
chr13_+_52436111 0.11 ENST00000242819.4
CCDC70
coiled-coil domain containing 70
chr17_-_9929581 0.11 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr20_-_61569296 0.11 ENST00000370371.4
DIDO1
death inducer-obliterator 1
chr1_+_27114418 0.10 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr11_-_40314652 0.10 ENST00000527150.1
LRRC4C
leucine rich repeat containing 4C
chr12_+_104682496 0.10 ENST00000378070.4
TXNRD1
thioredoxin reductase 1
chr1_+_27114589 0.10 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr12_-_58240470 0.09 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_+_172502336 0.09 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chr20_+_62697564 0.09 ENST00000458442.1
TCEA2
transcription elongation factor A (SII), 2
chr19_-_49371711 0.09 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr6_+_26045603 0.09 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr2_+_233734994 0.08 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr2_+_234296792 0.08 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr5_-_34916871 0.07 ENST00000382038.2
RAD1
RAD1 homolog (S. pombe)
chr5_-_78281775 0.07 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr19_+_41117770 0.07 ENST00000601032.1
LTBP4
latent transforming growth factor beta binding protein 4
chr6_-_32160622 0.07 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr11_+_47279504 0.07 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr20_-_61569227 0.06 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
DIDO1
death inducer-obliterator 1
chr11_+_19138670 0.06 ENST00000446113.2
ENST00000399351.3
ZDHHC13
zinc finger, DHHC-type containing 13
chr14_+_32030582 0.06 ENST00000550649.1
ENST00000281081.7
NUBPL
nucleotide binding protein-like
chr5_+_102455968 0.06 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr11_+_58910295 0.06 ENST00000420244.1
FAM111A
family with sequence similarity 111, member A
chr2_-_179343226 0.06 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr1_+_151043070 0.05 ENST00000368918.3
ENST00000368917.1
GABPB2
GA binding protein transcription factor, beta subunit 2
chr5_+_102455853 0.05 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr6_-_8064567 0.05 ENST00000543936.1
ENST00000397457.2
BLOC1S5
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr1_+_171750776 0.05 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13
methyltransferase like 13
chr17_+_7788104 0.05 ENST00000380358.4
CHD3
chromodomain helicase DNA binding protein 3
chr4_-_83295103 0.05 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr4_+_667686 0.05 ENST00000505477.1
MYL5
myosin, light chain 5, regulatory
chr14_+_24025194 0.04 ENST00000404535.3
ENST00000288014.6
THTPA
thiamine triphosphatase
chr19_-_11639931 0.04 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr16_+_15068916 0.04 ENST00000455313.2
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr2_-_179343268 0.04 ENST00000424785.2
FKBP7
FK506 binding protein 7
chr8_+_94712732 0.04 ENST00000518322.1
FAM92A1
family with sequence similarity 92, member A1
chr4_+_667307 0.03 ENST00000506838.1
MYL5
myosin, light chain 5, regulatory
chr19_-_11639910 0.03 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr16_+_15068955 0.03 ENST00000396410.4
ENST00000569715.1
ENST00000450288.2
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr7_+_90893783 0.03 ENST00000287934.2
FZD1
frizzled family receptor 1
chr2_+_219264466 0.03 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr19_+_50180317 0.03 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr9_-_16727978 0.03 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr1_+_55107449 0.03 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
MROH7
maestro heat-like repeat family member 7
chr8_+_81397846 0.03 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr5_+_159343688 0.02 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr7_-_38398721 0.02 ENST00000390346.2
TRGV3
T cell receptor gamma variable 3
chr7_-_23571586 0.02 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
TRA2A
transformer 2 alpha homolog (Drosophila)
chr11_+_8040739 0.02 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr22_-_39636914 0.02 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr1_+_6511651 0.02 ENST00000434576.1
ESPN
espin
chr5_-_102455801 0.02 ENST00000508629.1
ENST00000399004.2
GIN1
gypsy retrotransposon integrase 1
chr16_+_88636789 0.01 ENST00000301011.5
ENST00000452588.2
ZC3H18
zinc finger CCCH-type containing 18
chr22_+_38864041 0.01 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr9_+_17135016 0.01 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr2_-_8723918 0.01 ENST00000454224.1
AC011747.4
AC011747.4

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.3 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.2 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.0 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.0 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)