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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PTF1A

Z-value: 0.67

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Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
PTF1A
ENSG00000168267.5 pancreas associated transcription factor 1a

Activity profile of PTF1A motif

Sorted Z-values of PTF1A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_9129598 1.22 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr15_-_89764929 1.03 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr11_-_111794446 0.84 ENST00000527950.1
CRYAB
crystallin, alpha B
chr8_-_22089845 0.79 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr8_-_22089533 0.74 ENST00000321613.3
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr1_+_150480576 0.72 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr12_+_109826524 0.72 ENST00000431443.2
MYO1H
myosin IH
chr1_+_150480551 0.70 ENST00000369049.4
ENST00000369047.4
ECM1
extracellular matrix protein 1
chr20_+_44637526 0.66 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr21_+_44073916 0.64 ENST00000349112.3
ENST00000398224.3
PDE9A
phosphodiesterase 9A
chr22_-_50050986 0.61 ENST00000405854.1
C22orf34
chromosome 22 open reading frame 34
chr21_+_44073860 0.59 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
PDE9A
phosphodiesterase 9A
chr22_-_50051151 0.58 ENST00000400023.1
ENST00000444628.1
C22orf34
chromosome 22 open reading frame 34
chr11_-_1643368 0.58 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr4_+_40198527 0.55 ENST00000381799.5
RHOH
ras homolog family member H
chr6_-_46620522 0.52 ENST00000275016.2
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr2_+_120187465 0.51 ENST00000409826.1
ENST00000417645.1
TMEM37
transmembrane protein 37
chr1_-_204654826 0.50 ENST00000367177.3
LRRN2
leucine rich repeat neuronal 2
chr19_-_46526304 0.49 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr8_+_11351494 0.48 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr3_-_193272874 0.46 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr13_+_113812956 0.43 ENST00000375547.2
ENST00000342783.4
PROZ
protein Z, vitamin K-dependent plasma glycoprotein
chr11_-_1629693 0.42 ENST00000399685.1
KRTAP5-3
keratin associated protein 5-3
chr19_+_11670245 0.41 ENST00000585493.1
ZNF627
zinc finger protein 627
chr1_-_45956800 0.40 ENST00000538496.1
TESK2
testis-specific kinase 2
chr8_+_11351876 0.38 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr5_+_140557371 0.37 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr17_+_53342311 0.34 ENST00000226067.5
HLF
hepatic leukemia factor
chr17_-_43487741 0.34 ENST00000455881.1
ARHGAP27
Rho GTPase activating protein 27
chr7_+_150688166 0.34 ENST00000461406.1
NOS3
nitric oxide synthase 3 (endothelial cell)
chr12_-_75603482 0.32 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr12_+_1929644 0.32 ENST00000299194.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr4_+_156587979 0.31 ENST00000511507.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr12_-_75603643 0.30 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr22_-_50523760 0.30 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr8_-_99306564 0.29 ENST00000430223.2
NIPAL2
NIPA-like domain containing 2
chr2_-_89278535 0.28 ENST00000390247.2
IGKV3-7
immunoglobulin kappa variable 3-7 (non-functional)
chr3_-_52868931 0.28 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr8_-_99306611 0.28 ENST00000341166.3
NIPAL2
NIPA-like domain containing 2
chrX_-_21676442 0.27 ENST00000379499.2
KLHL34
kelch-like family member 34
chr1_-_9129735 0.26 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr5_+_78532003 0.26 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr12_+_1929421 0.26 ENST00000543818.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr1_-_9129895 0.26 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr10_-_28571015 0.26 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_+_173600514 0.26 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr10_-_1779663 0.26 ENST00000381312.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr14_-_77737543 0.25 ENST00000298352.4
NGB
neuroglobin
chr8_-_125577940 0.25 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr3_-_52869205 0.25 ENST00000446157.2
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr2_+_173600565 0.24 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr11_-_45687128 0.24 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr5_+_173315283 0.24 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_-_9129631 0.24 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr10_+_99332198 0.24 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr21_-_46012386 0.23 ENST00000400368.1
KRTAP10-6
keratin associated protein 10-6
chr11_-_63933504 0.22 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr2_-_228497888 0.22 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83
chr19_-_17014408 0.22 ENST00000594249.1
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr3_+_40518599 0.22 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr1_-_45956822 0.22 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chrX_-_107019181 0.21 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3
TSC22 domain family, member 3
chr6_+_27107053 0.21 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr22_+_24999114 0.21 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr2_-_239140011 0.20 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
AC016757.3
Protein LOC151174
chr17_+_40996590 0.20 ENST00000253799.3
ENST00000452774.2
AOC2
amine oxidase, copper containing 2 (retina-specific)
chr9_-_19033237 0.20 ENST00000380530.1
ENST00000542071.1
FAM154A
family with sequence similarity 154, member A
chr20_-_44259893 0.20 ENST00000326000.1
WFDC9
WAP four-disulfide core domain 9
chr9_+_4985228 0.20 ENST00000381652.3
JAK2
Janus kinase 2
chr9_-_19033185 0.20 ENST00000380534.4
FAM154A
family with sequence similarity 154, member A
chr10_-_101841588 0.20 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr14_+_77292715 0.20 ENST00000393774.3
ENST00000555189.1
ENST00000450042.2
C14orf166B
chromosome 14 open reading frame 166B
chr20_+_30697298 0.19 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr12_+_50451331 0.19 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr18_-_5238525 0.19 ENST00000581170.1
ENST00000579933.1
ENST00000581067.1
RP11-835E18.5
LINC00526
RP11-835E18.5
long intergenic non-protein coding RNA 526
chr7_+_30323923 0.19 ENST00000323037.4
ZNRF2
zinc and ring finger 2
chr7_-_99097863 0.18 ENST00000426306.2
ENST00000337673.6
ZNF394
zinc finger protein 394
chr15_+_41099788 0.18 ENST00000299173.10
ENST00000566407.1
ZFYVE19
zinc finger, FYVE domain containing 19
chr16_-_2004683 0.17 ENST00000268661.7
RPL3L
ribosomal protein L3-like
chr11_+_64052454 0.17 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr2_-_160761179 0.17 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
LY75
LY75-CD302
lymphocyte antigen 75
LY75-CD302 readthrough
chrX_-_48216101 0.17 ENST00000298396.2
ENST00000376893.3
SSX3
synovial sarcoma, X breakpoint 3
chr2_-_89513402 0.17 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr2_-_71454185 0.17 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr12_+_113344755 0.17 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr7_-_152373216 0.16 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr11_+_64052692 0.16 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chrX_-_134305322 0.16 ENST00000276241.6
ENST00000344129.2
CXorf48
cancer/testis antigen 55
chr1_-_158301312 0.15 ENST00000368168.3
CD1B
CD1b molecule
chr2_+_85922491 0.15 ENST00000526018.1
GNLY
granulysin
chr13_-_79979919 0.15 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr11_+_64107663 0.15 ENST00000356786.5
CCDC88B
coiled-coil domain containing 88B
chr3_-_195938256 0.15 ENST00000296326.3
ZDHHC19
zinc finger, DHHC-type containing 19
chr11_+_64052294 0.14 ENST00000536667.1
GPR137
G protein-coupled receptor 137
chr20_+_42544782 0.14 ENST00000423191.2
ENST00000372999.1
TOX2
TOX high mobility group box family member 2
chr1_+_178694300 0.14 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr4_+_183370146 0.14 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr4_-_14889791 0.14 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr3_-_172241250 0.13 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr12_+_31079652 0.13 ENST00000546076.1
ENST00000535215.1
ENST00000544427.1
ENST00000261177.9
TSPAN11
tetraspanin 11
chr6_-_41715128 0.13 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC
progastricsin (pepsinogen C)
chr2_+_97426631 0.13 ENST00000377075.2
CNNM4
cyclin M4
chr1_+_32084794 0.13 ENST00000373705.1
HCRTR1
hypocretin (orexin) receptor 1
chr8_-_135725205 0.13 ENST00000523399.1
ENST00000377838.3
ZFAT
zinc finger and AT hook domain containing
chr14_-_35099315 0.13 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
SNX6
sorting nexin 6
chr4_-_123843597 0.13 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr13_-_79979952 0.13 ENST00000438724.1
RBM26
RNA binding motif protein 26
chr6_-_62996066 0.13 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr11_+_64052266 0.13 ENST00000539851.1
GPR137
G protein-coupled receptor 137
chr1_-_114447683 0.12 ENST00000256658.4
ENST00000369564.1
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr1_-_114447620 0.12 ENST00000369569.1
ENST00000432415.1
ENST00000369571.2
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr2_-_237416181 0.12 ENST00000409907.3
IQCA1
IQ motif containing with AAA domain 1
chr4_-_89744457 0.12 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr15_+_84841242 0.12 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr17_+_79859985 0.12 ENST00000333383.7
NPB
neuropeptide B
chr2_-_237416071 0.12 ENST00000309507.5
ENST00000431676.2
IQCA1
IQ motif containing with AAA domain 1
chr19_-_10491130 0.12 ENST00000530829.1
ENST00000529370.1
TYK2
tyrosine kinase 2
chr12_-_57644952 0.12 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3
SH3 and cysteine rich domain 3
chr9_-_104145795 0.12 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr5_+_132149017 0.11 ENST00000378693.2
SOWAHA
sosondowah ankyrin repeat domain family member A
chr6_-_159466042 0.11 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr16_+_2802623 0.11 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2
serine/arginine repetitive matrix 2
chr7_-_142207004 0.11 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chr2_-_196933536 0.11 ENST00000312428.6
ENST00000410072.1
DNAH7
dynein, axonemal, heavy chain 7
chr4_-_89744314 0.11 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr2_+_44066101 0.11 ENST00000272286.2
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr5_-_162887071 0.11 ENST00000302764.4
NUDCD2
NudC domain containing 2
chr10_+_76871454 0.11 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr12_+_113344811 0.11 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr4_-_89744365 0.11 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr10_-_96829246 0.10 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr19_+_17326521 0.10 ENST00000593597.1
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr11_+_71238313 0.10 ENST00000398536.4
KRTAP5-7
keratin associated protein 5-7
chr11_-_102576537 0.10 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr17_-_3375033 0.10 ENST00000268981.5
ENST00000397168.3
ENST00000572969.1
ENST00000355380.4
ENST00000571553.1
ENST00000574797.1
ENST00000575375.1
SPATA22
spermatogenesis associated 22
chr12_-_50677255 0.10 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chr11_-_61735103 0.10 ENST00000529191.1
ENST00000529631.1
ENST00000530019.1
ENST00000529548.1
ENST00000273550.7
FTH1
ferritin, heavy polypeptide 1
chr3_+_101546827 0.10 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr11_+_96123158 0.10 ENST00000332349.4
ENST00000458427.1
JRKL
jerky homolog-like (mouse)
chr11_+_7597639 0.09 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr18_+_5238055 0.09 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
LINC00667
long intergenic non-protein coding RNA 667
chr11_+_64058758 0.09 ENST00000538767.1
KCNK4
potassium channel, subfamily K, member 4
chr12_+_112451120 0.09 ENST00000261735.3
ENST00000455836.1
ERP29
endoplasmic reticulum protein 29
chr3_+_35721182 0.09 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr9_-_116061145 0.09 ENST00000416588.2
RNF183
ring finger protein 183
chr17_-_34313685 0.09 ENST00000435911.2
ENST00000586216.1
ENST00000394509.4
CCL14
chemokine (C-C motif) ligand 14
chr1_-_76076759 0.09 ENST00000370855.5
SLC44A5
solute carrier family 44, member 5
chr7_+_7606497 0.09 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chr10_+_49892904 0.08 ENST00000360890.2
WDFY4
WDFY family member 4
chr19_+_54495542 0.08 ENST00000252729.2
ENST00000352529.1
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chr4_+_156588115 0.08 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr10_-_5855350 0.08 ENST00000456041.1
ENST00000380181.3
ENST00000418688.1
ENST00000380132.4
ENST00000609712.1
ENST00000380191.4
GDI2
GDP dissociation inhibitor 2
chr2_-_86422523 0.08 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
IMMT
inner membrane protein, mitochondrial
chr12_+_53689309 0.08 ENST00000351500.3
ENST00000550846.1
ENST00000334478.4
ENST00000549759.1
PFDN5
prefoldin subunit 5
chr6_-_24489842 0.08 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr1_+_231114795 0.08 ENST00000310256.2
ENST00000366658.2
ENST00000450711.1
ENST00000435927.1
ARV1
ARV1 homolog (S. cerevisiae)
chr4_+_156587853 0.08 ENST00000506455.1
ENST00000511108.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr5_-_162887054 0.07 ENST00000517501.1
NUDCD2
NudC domain containing 2
chr9_+_33795533 0.07 ENST00000379405.3
PRSS3
protease, serine, 3
chr12_+_52281744 0.07 ENST00000301190.6
ENST00000538991.1
ANKRD33
ankyrin repeat domain 33
chr11_+_71249071 0.07 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr3_-_12883026 0.07 ENST00000396953.2
ENST00000457131.1
ENST00000435983.1
ENST00000273223.6
ENST00000396957.1
ENST00000429711.2
RPL32
ribosomal protein L32
chr5_+_56205878 0.07 ENST00000423328.1
SETD9
SET domain containing 9
chr4_+_184826418 0.07 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr5_-_16916624 0.07 ENST00000513882.1
MYO10
myosin X
chr1_-_114447412 0.07 ENST00000369567.1
ENST00000369566.3
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr6_-_159466136 0.06 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chr11_+_8704748 0.06 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr14_-_35099377 0.06 ENST00000362031.4
SNX6
sorting nexin 6
chr9_-_138853156 0.06 ENST00000371756.3
UBAC1
UBA domain containing 1
chr19_-_10491234 0.06 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr1_+_171454659 0.05 ENST00000367742.3
ENST00000338920.4
PRRC2C
proline-rich coiled-coil 2C
chr19_+_42300548 0.05 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr16_-_75569068 0.05 ENST00000336257.3
ENST00000565039.1
CHST5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr1_+_228337553 0.05 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr2_-_237412331 0.05 ENST00000418802.1
IQCA1
IQ motif containing with AAA domain 1
chrX_-_44402231 0.05 ENST00000378045.4
FUNDC1
FUN14 domain containing 1
chr19_-_11039261 0.04 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
YIPF2
Yip1 domain family, member 2
chr6_-_2962331 0.04 ENST00000380524.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr17_-_73892992 0.04 ENST00000540128.1
ENST00000269383.3
TRIM65
tripartite motif containing 65
chr16_+_2802316 0.04 ENST00000301740.8
SRRM2
serine/arginine repetitive matrix 2
chr17_+_6918064 0.04 ENST00000546760.1
ENST00000552402.1
C17orf49
chromosome 17 open reading frame 49
chr12_+_113344582 0.04 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr20_+_48892848 0.04 ENST00000422459.1
RP11-290F20.3
RP11-290F20.3
chr11_-_207221 0.04 ENST00000486280.1
ENST00000332865.6
ENST00000529614.2
ENST00000325147.9
ENST00000410108.1
ENST00000382762.3
BET1L
Bet1 golgi vesicular membrane trafficking protein-like
chr11_-_89609185 0.04 ENST00000329862.6
TRIM64B
tripartite motif containing 64B
chrX_+_15808569 0.04 ENST00000380308.3
ENST00000307771.7
ZRSR2
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr19_+_54496132 0.04 ENST00000346968.2
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chr1_+_100503643 0.04 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr4_-_175750364 0.04 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3
chr1_+_171454639 0.04 ENST00000392078.3
ENST00000426496.2
PRRC2C
proline-rich coiled-coil 2C
chr16_+_89696692 0.04 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr1_+_32084641 0.03 ENST00000373706.5
HCRTR1
hypocretin (orexin) receptor 1
chr16_-_15950868 0.03 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
MYH11
myosin, heavy chain 11, smooth muscle
chr14_+_70346125 0.03 ENST00000361956.3
ENST00000381280.4
SMOC1
SPARC related modular calcium binding 1
chr19_+_19779686 0.03 ENST00000415784.2
ZNF101
zinc finger protein 101
chr2_+_27435179 0.03 ENST00000606999.1
ENST00000405489.3
ATRAID
all-trans retinoic acid-induced differentiation factor
chr1_+_12185949 0.03 ENST00000413146.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr3_+_167453493 0.02 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_-_89417335 0.02 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17

Network of associatons between targets according to the STRING database.

First level regulatory network of PTF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:1990539 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.2 0.5 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.3 GO:0014806 negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806)
0.1 0.5 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.6 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.7 GO:2001268 positive regulation of keratinocyte migration(GO:0051549) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 1.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 1.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.2 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.2 GO:1902724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0060752 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.4 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.4 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.9 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 1.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 2.0 GO:0035579 specific granule membrane(GO:0035579)
0.0 2.2 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.2 1.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.5 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.2 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 1.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 2.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1