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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for RAD21_SMC3
Z-value: 1.53
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Transcription factors associated with RAD21_SMC3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RAD21
|
ENSG00000164754.8 | RAD21 cohesin complex component |
|
SMC3
|
ENSG00000108055.9 | structural maintenance of chromosomes 3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SMC3 | hg19_v2_chr10_+_112327425_112327516 | -0.57 | 8.9e-04 | Click! |
| RAD21 | hg19_v2_chr8_-_117886955_117887105 | 0.00 | 9.8e-01 | Click! |
Activity profile of RAD21_SMC3 motif
Sorted Z-values of RAD21_SMC3 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_114737472 | 15.24 |
ENST00000420161.1
|
AC110769.3
|
AC110769.3 |
| chr15_+_45722727 | 9.17 |
ENST00000396650.2
ENST00000558435.1 ENST00000344300.3 |
C15orf48
|
chromosome 15 open reading frame 48 |
| chr5_+_148521381 | 8.05 |
ENST00000504238.1
|
ABLIM3
|
actin binding LIM protein family, member 3 |
| chr5_-_136834982 | 7.44 |
ENST00000510689.1
ENST00000394945.1 |
SPOCK1
|
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| chr5_+_148521046 | 7.39 |
ENST00000326685.7
ENST00000356541.3 ENST00000309868.7 |
ABLIM3
|
actin binding LIM protein family, member 3 |
| chr5_+_148521136 | 7.28 |
ENST00000506113.1
|
ABLIM3
|
actin binding LIM protein family, member 3 |
| chr2_+_114737146 | 6.20 |
ENST00000412690.1
|
AC010982.1
|
AC010982.1 |
| chr19_-_19051927 | 4.88 |
ENST00000600077.1
|
HOMER3
|
homer homolog 3 (Drosophila) |
| chr5_-_139726181 | 4.75 |
ENST00000507104.1
ENST00000230990.6 |
HBEGF
|
heparin-binding EGF-like growth factor |
| chr14_-_75079026 | 4.69 |
ENST00000261978.4
|
LTBP2
|
latent transforming growth factor beta binding protein 2 |
| chr11_+_118826999 | 4.46 |
ENST00000264031.2
|
UPK2
|
uroplakin 2 |
| chr19_-_19051993 | 4.33 |
ENST00000594794.1
ENST00000355887.6 ENST00000392351.3 ENST00000596482.1 |
HOMER3
|
homer homolog 3 (Drosophila) |
| chr7_+_302918 | 4.32 |
ENST00000599994.1
|
AC187652.1
|
Protein LOC100996433 |
| chr9_-_22009241 | 4.28 |
ENST00000380142.4
|
CDKN2B
|
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| chr9_+_131182697 | 4.06 |
ENST00000372838.4
ENST00000411852.1 |
CERCAM
|
cerebral endothelial cell adhesion molecule |
| chr18_-_21166841 | 3.98 |
ENST00000269228.5
|
NPC1
|
Niemann-Pick disease, type C1 |
| chr4_+_7194247 | 3.79 |
ENST00000507866.2
|
SORCS2
|
sortilin-related VPS10 domain containing receptor 2 |
| chr10_-_76995675 | 3.72 |
ENST00000469299.1
|
COMTD1
|
catechol-O-methyltransferase domain containing 1 |
| chr19_-_55652290 | 3.69 |
ENST00000589745.1
|
TNNT1
|
troponin T type 1 (skeletal, slow) |
| chr19_+_48216600 | 3.55 |
ENST00000263277.3
ENST00000538399.1 |
EHD2
|
EH-domain containing 2 |
| chr10_-_76995769 | 3.47 |
ENST00000372538.3
|
COMTD1
|
catechol-O-methyltransferase domain containing 1 |
| chr16_+_66638685 | 3.44 |
ENST00000565003.1
|
CMTM3
|
CKLF-like MARVEL transmembrane domain containing 3 |
| chr20_+_30102231 | 3.43 |
ENST00000335574.5
ENST00000340852.5 ENST00000398174.3 ENST00000376127.3 ENST00000344042.5 |
HM13
|
histocompatibility (minor) 13 |
| chr1_-_75198940 | 3.28 |
ENST00000417775.1
|
CRYZ
|
crystallin, zeta (quinone reductase) |
| chr19_-_55653259 | 3.23 |
ENST00000593194.1
|
TNNT1
|
troponin T type 1 (skeletal, slow) |
| chr6_+_151186554 | 3.15 |
ENST00000367321.3
ENST00000367307.4 |
MTHFD1L
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like |
| chr15_+_63340734 | 3.14 |
ENST00000560959.1
|
TPM1
|
tropomyosin 1 (alpha) |
| chr12_-_95510743 | 3.12 |
ENST00000551521.1
|
FGD6
|
FYVE, RhoGEF and PH domain containing 6 |
| chr2_-_72375167 | 3.07 |
ENST00000001146.2
|
CYP26B1
|
cytochrome P450, family 26, subfamily B, polypeptide 1 |
| chr10_+_17272608 | 3.06 |
ENST00000421459.2
|
VIM
|
vimentin |
| chr8_+_28480246 | 3.05 |
ENST00000523149.1
|
EXTL3
|
exostosin-like glycosyltransferase 3 |
| chr21_-_44846999 | 3.04 |
ENST00000270162.6
|
SIK1
|
salt-inducible kinase 1 |
| chr15_+_63340775 | 3.00 |
ENST00000559281.1
ENST00000317516.7 |
TPM1
|
tropomyosin 1 (alpha) |
| chr1_+_10270863 | 2.93 |
ENST00000377093.4
ENST00000263934.6 |
KIF1B
|
kinesin family member 1B |
| chr1_+_37940153 | 2.91 |
ENST00000373087.6
|
ZC3H12A
|
zinc finger CCCH-type containing 12A |
| chr15_+_63340553 | 2.89 |
ENST00000334895.5
|
TPM1
|
tropomyosin 1 (alpha) |
| chr15_+_63340647 | 2.79 |
ENST00000404484.4
|
TPM1
|
tropomyosin 1 (alpha) |
| chr17_-_72358001 | 2.71 |
ENST00000375366.3
|
BTBD17
|
BTB (POZ) domain containing 17 |
| chr17_+_1958388 | 2.65 |
ENST00000399849.3
|
HIC1
|
hypermethylated in cancer 1 |
| chr5_-_76788317 | 2.62 |
ENST00000296679.4
|
WDR41
|
WD repeat domain 41 |
| chr15_+_74165945 | 2.59 |
ENST00000535547.2
ENST00000300504.2 ENST00000562056.1 |
TBC1D21
|
TBC1 domain family, member 21 |
| chr2_+_228337079 | 2.58 |
ENST00000409315.1
ENST00000373671.3 ENST00000409171.1 |
AGFG1
|
ArfGAP with FG repeats 1 |
| chr11_+_60691924 | 2.55 |
ENST00000544065.1
ENST00000453848.2 ENST00000005286.4 |
TMEM132A
|
transmembrane protein 132A |
| chr17_-_43209862 | 2.52 |
ENST00000322765.5
|
PLCD3
|
phospholipase C, delta 3 |
| chr7_+_89783689 | 2.47 |
ENST00000297205.2
|
STEAP1
|
six transmembrane epithelial antigen of the prostate 1 |
| chr19_-_4400415 | 2.43 |
ENST00000598564.1
ENST00000417295.2 ENST00000269886.3 |
SH3GL1
|
SH3-domain GRB2-like 1 |
| chr5_-_76788024 | 2.37 |
ENST00000515253.1
ENST00000414719.2 ENST00000507654.1 ENST00000514559.1 ENST00000511791.1 |
WDR41
|
WD repeat domain 41 |
| chr11_-_66104237 | 2.36 |
ENST00000530056.1
|
RIN1
|
Ras and Rab interactor 1 |
| chr1_-_159915386 | 2.35 |
ENST00000361509.3
ENST00000368094.1 |
IGSF9
|
immunoglobulin superfamily, member 9 |
| chr5_-_76788134 | 2.31 |
ENST00000507029.1
|
WDR41
|
WD repeat domain 41 |
| chr19_-_36001113 | 2.24 |
ENST00000434389.1
|
DMKN
|
dermokine |
| chr16_+_1756162 | 2.19 |
ENST00000250894.4
ENST00000356010.5 |
MAPK8IP3
|
mitogen-activated protein kinase 8 interacting protein 3 |
| chr3_-_183735731 | 2.16 |
ENST00000334444.6
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| chr19_-_41859814 | 2.14 |
ENST00000221930.5
|
TGFB1
|
transforming growth factor, beta 1 |
| chr16_-_88851618 | 2.11 |
ENST00000301015.9
|
PIEZO1
|
piezo-type mechanosensitive ion channel component 1 |
| chr10_-_30024716 | 2.11 |
ENST00000375398.2
ENST00000375400.3 |
SVIL
|
supervillin |
| chr17_-_45908875 | 2.09 |
ENST00000351111.2
ENST00000414011.1 |
MRPL10
|
mitochondrial ribosomal protein L10 |
| chr3_+_172468472 | 2.08 |
ENST00000232458.5
ENST00000392692.3 |
ECT2
|
epithelial cell transforming sequence 2 oncogene |
| chr14_+_22508822 | 2.07 |
ENST00000390448.3
|
TRAV20
|
T cell receptor alpha variable 20 |
| chr10_+_99332198 | 2.04 |
ENST00000307518.5
ENST00000298808.5 ENST00000370655.1 |
ANKRD2
|
ankyrin repeat domain 2 (stretch responsive muscle) |
| chr19_-_49339080 | 2.02 |
ENST00000595764.1
|
HSD17B14
|
hydroxysteroid (17-beta) dehydrogenase 14 |
| chr20_-_30311703 | 1.98 |
ENST00000450273.1
ENST00000456404.1 ENST00000420488.1 ENST00000439267.1 |
BCL2L1
|
BCL2-like 1 |
| chr7_-_5569588 | 1.98 |
ENST00000417101.1
|
ACTB
|
actin, beta |
| chr9_+_103189405 | 1.97 |
ENST00000395067.2
|
MSANTD3
|
Myb/SANT-like DNA-binding domain containing 3 |
| chr22_-_22292934 | 1.96 |
ENST00000538191.1
ENST00000424647.1 ENST00000407142.1 |
PPM1F
|
protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| chr19_-_15590306 | 1.96 |
ENST00000292609.4
|
PGLYRP2
|
peptidoglycan recognition protein 2 |
| chr9_+_103189536 | 1.95 |
ENST00000374885.1
|
MSANTD3
|
Myb/SANT-like DNA-binding domain containing 3 |
| chr11_-_66103932 | 1.93 |
ENST00000311320.4
|
RIN1
|
Ras and Rab interactor 1 |
| chr3_+_49209023 | 1.93 |
ENST00000332780.2
|
KLHDC8B
|
kelch domain containing 8B |
| chr3_+_172468505 | 1.92 |
ENST00000427830.1
ENST00000417960.1 ENST00000428567.1 ENST00000366090.2 ENST00000426894.1 |
ECT2
|
epithelial cell transforming sequence 2 oncogene |
| chr17_-_42441204 | 1.91 |
ENST00000293443.7
|
FAM171A2
|
family with sequence similarity 171, member A2 |
| chr19_-_19754354 | 1.90 |
ENST00000587238.1
|
GMIP
|
GEM interacting protein |
| chr19_-_36001286 | 1.89 |
ENST00000602679.1
ENST00000492341.2 ENST00000472252.2 ENST00000602781.1 ENST00000402589.2 ENST00000458071.1 ENST00000436012.1 ENST00000443640.1 ENST00000450261.1 ENST00000467637.1 ENST00000480502.1 ENST00000474928.1 ENST00000414866.2 ENST00000392206.2 ENST00000488892.1 |
DMKN
|
dermokine |
| chr8_+_54764346 | 1.88 |
ENST00000297313.3
ENST00000344277.6 |
RGS20
|
regulator of G-protein signaling 20 |
| chr1_-_156675535 | 1.86 |
ENST00000368221.1
|
CRABP2
|
cellular retinoic acid binding protein 2 |
| chr19_-_4791219 | 1.85 |
ENST00000598782.1
|
AC005523.3
|
AC005523.3 |
| chr3_-_183735651 | 1.84 |
ENST00000427120.2
ENST00000392579.2 ENST00000382494.2 ENST00000446941.2 |
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| chr16_-_90085824 | 1.83 |
ENST00000002501.6
|
DBNDD1
|
dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| chr1_+_10092890 | 1.81 |
ENST00000253251.8
ENST00000377157.3 |
UBE4B
|
ubiquitination factor E4B |
| chr2_+_228678550 | 1.81 |
ENST00000409189.3
ENST00000358813.4 |
CCL20
|
chemokine (C-C motif) ligand 20 |
| chr11_-_66103867 | 1.77 |
ENST00000424433.2
|
RIN1
|
Ras and Rab interactor 1 |
| chr1_+_203651937 | 1.77 |
ENST00000341360.2
|
ATP2B4
|
ATPase, Ca++ transporting, plasma membrane 4 |
| chr15_-_34659349 | 1.75 |
ENST00000314891.6
|
LPCAT4
|
lysophosphatidylcholine acyltransferase 4 |
| chr6_+_35310312 | 1.73 |
ENST00000448077.2
ENST00000360694.3 ENST00000418635.2 ENST00000444397.1 |
PPARD
|
peroxisome proliferator-activated receptor delta |
| chr10_-_76868931 | 1.72 |
ENST00000372700.3
ENST00000473072.2 ENST00000491677.2 ENST00000607131.1 ENST00000372702.3 |
DUSP13
|
dual specificity phosphatase 13 |
| chr11_-_85565906 | 1.72 |
ENST00000544076.1
|
AP000974.1
|
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein |
| chr22_-_50050986 | 1.71 |
ENST00000405854.1
|
C22orf34
|
chromosome 22 open reading frame 34 |
| chr17_+_72199721 | 1.70 |
ENST00000439590.2
ENST00000311111.6 ENST00000584577.1 ENST00000534490.1 ENST00000528433.2 ENST00000533498.1 |
RPL38
|
ribosomal protein L38 |
| chr5_-_125930929 | 1.70 |
ENST00000553117.1
ENST00000447989.2 ENST00000409134.3 |
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1 |
| chr3_-_196756646 | 1.70 |
ENST00000439320.1
ENST00000296351.4 ENST00000296350.5 |
MFI2
|
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| chr10_+_99332529 | 1.68 |
ENST00000455090.1
|
ANKRD2
|
ankyrin repeat domain 2 (stretch responsive muscle) |
| chr2_-_24307635 | 1.67 |
ENST00000313482.4
|
TP53I3
|
tumor protein p53 inducible protein 3 |
| chr12_-_120703523 | 1.66 |
ENST00000267257.7
ENST00000228307.7 ENST00000424649.2 |
PXN
|
paxillin |
| chr7_+_1126461 | 1.65 |
ENST00000297469.3
|
GPER1
|
G protein-coupled estrogen receptor 1 |
| chr17_+_7621045 | 1.65 |
ENST00000570791.1
|
DNAH2
|
dynein, axonemal, heavy chain 2 |
| chr6_+_34482630 | 1.65 |
ENST00000538621.1
|
PACSIN1
|
protein kinase C and casein kinase substrate in neurons 1 |
| chr3_-_50340996 | 1.63 |
ENST00000266031.4
ENST00000395143.2 ENST00000457214.2 ENST00000447605.2 ENST00000418723.1 ENST00000395144.2 |
HYAL1
|
hyaluronoglucosaminidase 1 |
| chr6_+_35310391 | 1.62 |
ENST00000337400.2
ENST00000311565.4 ENST00000540939.1 |
PPARD
|
peroxisome proliferator-activated receptor delta |
| chr11_+_119076745 | 1.59 |
ENST00000264033.4
|
CBL
|
Cbl proto-oncogene, E3 ubiquitin protein ligase |
| chr11_-_119599794 | 1.59 |
ENST00000264025.3
|
PVRL1
|
poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| chr19_-_19754404 | 1.57 |
ENST00000587205.1
ENST00000445806.2 ENST00000203556.4 |
GMIP
|
GEM interacting protein |
| chr11_+_85566422 | 1.56 |
ENST00000342404.3
|
CCDC83
|
coiled-coil domain containing 83 |
| chr20_+_43992094 | 1.56 |
ENST00000453003.1
|
SYS1
|
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae) |
| chr14_+_23305760 | 1.54 |
ENST00000311852.6
|
MMP14
|
matrix metallopeptidase 14 (membrane-inserted) |
| chr17_+_45810594 | 1.54 |
ENST00000177694.1
|
TBX21
|
T-box 21 |
| chr14_+_52118576 | 1.54 |
ENST00000395718.2
ENST00000344768.5 |
FRMD6
|
FERM domain containing 6 |
| chr14_+_22265444 | 1.53 |
ENST00000390430.2
|
TRAV8-1
|
T cell receptor alpha variable 8-1 |
| chr17_+_74864476 | 1.52 |
ENST00000301618.4
ENST00000569840.2 |
MGAT5B
|
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B |
| chr3_+_5163905 | 1.51 |
ENST00000256496.3
ENST00000419534.2 |
ARL8B
|
ADP-ribosylation factor-like 8B |
| chr11_-_117103208 | 1.51 |
ENST00000320934.3
ENST00000530269.1 |
PCSK7
|
proprotein convertase subtilisin/kexin type 7 |
| chr14_+_105190514 | 1.51 |
ENST00000330877.2
|
ADSSL1
|
adenylosuccinate synthase like 1 |
| chr15_-_38856836 | 1.50 |
ENST00000450598.2
ENST00000559830.1 ENST00000558164.1 ENST00000310803.5 |
RASGRP1
|
RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| chr17_-_40833858 | 1.50 |
ENST00000332438.4
|
CCR10
|
chemokine (C-C motif) receptor 10 |
| chr19_+_56165480 | 1.46 |
ENST00000450554.2
|
U2AF2
|
U2 small nuclear RNA auxiliary factor 2 |
| chr8_+_22022800 | 1.45 |
ENST00000397814.3
|
BMP1
|
bone morphogenetic protein 1 |
| chr15_-_44487408 | 1.41 |
ENST00000402883.1
ENST00000417257.1 |
FRMD5
|
FERM domain containing 5 |
| chr22_-_46931191 | 1.36 |
ENST00000454637.1
|
CELSR1
|
cadherin, EGF LAG seven-pass G-type receptor 1 |
| chr1_+_212208919 | 1.36 |
ENST00000366991.4
ENST00000542077.1 |
DTL
|
denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| chr6_+_31105426 | 1.33 |
ENST00000547221.1
|
PSORS1C1
|
psoriasis susceptibility 1 candidate 1 |
| chr7_-_4923315 | 1.33 |
ENST00000399583.3
|
RADIL
|
Ras association and DIL domains |
| chr2_-_232395169 | 1.32 |
ENST00000305141.4
|
NMUR1
|
neuromedin U receptor 1 |
| chr9_+_116917807 | 1.31 |
ENST00000356083.3
|
COL27A1
|
collagen, type XXVII, alpha 1 |
| chr7_-_22539771 | 1.30 |
ENST00000406890.2
ENST00000424363.1 |
STEAP1B
|
STEAP family member 1B |
| chr2_-_24307162 | 1.29 |
ENST00000413037.1
ENST00000407482.1 |
TP53I3
|
tumor protein p53 inducible protein 3 |
| chr7_-_4923259 | 1.29 |
ENST00000536091.1
|
RADIL
|
Ras association and DIL domains |
| chr4_+_56814968 | 1.29 |
ENST00000422247.2
|
CEP135
|
centrosomal protein 135kDa |
| chr7_+_1126437 | 1.27 |
ENST00000413368.1
ENST00000397092.1 |
GPER1
|
G protein-coupled estrogen receptor 1 |
| chr10_+_104154229 | 1.25 |
ENST00000428099.1
ENST00000369966.3 |
NFKB2
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| chr16_+_2867228 | 1.24 |
ENST00000005995.3
ENST00000574813.1 |
PRSS21
|
protease, serine, 21 (testisin) |
| chr8_+_22022223 | 1.23 |
ENST00000306385.5
|
BMP1
|
bone morphogenetic protein 1 |
| chr5_-_140998616 | 1.22 |
ENST00000389054.3
ENST00000398562.2 ENST00000389057.5 ENST00000398566.3 ENST00000398557.4 ENST00000253811.6 |
DIAPH1
|
diaphanous-related formin 1 |
| chr3_+_50192499 | 1.21 |
ENST00000413852.1
|
SEMA3F
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| chr7_-_38407770 | 1.21 |
ENST00000390348.2
|
TRGV1
|
T cell receptor gamma variable 1 (non-functional) |
| chr3_-_128212016 | 1.20 |
ENST00000498200.1
ENST00000341105.2 |
GATA2
|
GATA binding protein 2 |
| chr14_+_22356029 | 1.19 |
ENST00000390437.2
|
TRAV12-2
|
T cell receptor alpha variable 12-2 |
| chr12_-_51663728 | 1.18 |
ENST00000603864.1
ENST00000605426.1 |
SMAGP
|
small cell adhesion glycoprotein |
| chr14_+_22309368 | 1.17 |
ENST00000390433.1
|
TRAV12-1
|
T cell receptor alpha variable 12-1 |
| chr17_-_9862772 | 1.17 |
ENST00000580865.1
ENST00000583882.1 |
GAS7
|
growth arrest-specific 7 |
| chr16_+_2867164 | 1.16 |
ENST00000455114.1
ENST00000450020.3 |
PRSS21
|
protease, serine, 21 (testisin) |
| chr22_+_22936998 | 1.16 |
ENST00000390303.2
|
IGLV3-32
|
immunoglobulin lambda variable 3-32 (non-functional) |
| chr9_+_139560197 | 1.15 |
ENST00000371698.3
|
EGFL7
|
EGF-like-domain, multiple 7 |
| chr18_+_60382672 | 1.14 |
ENST00000400316.4
ENST00000262719.5 |
PHLPP1
|
PH domain and leucine rich repeat protein phosphatase 1 |
| chr22_-_22307199 | 1.13 |
ENST00000397495.4
ENST00000263212.5 |
PPM1F
|
protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| chr3_+_156799587 | 1.12 |
ENST00000469196.1
|
RP11-6F2.5
|
RP11-6F2.5 |
| chr10_+_102759045 | 1.11 |
ENST00000370220.1
|
LZTS2
|
leucine zipper, putative tumor suppressor 2 |
| chr19_+_41860047 | 1.11 |
ENST00000604123.1
|
TMEM91
|
transmembrane protein 91 |
| chr3_+_141594966 | 1.11 |
ENST00000475483.1
|
ATP1B3
|
ATPase, Na+/K+ transporting, beta 3 polypeptide |
| chrX_-_27417088 | 1.10 |
ENST00000608735.1
ENST00000422048.1 |
RP11-268G12.1
|
RP11-268G12.1 |
| chr12_+_50898881 | 1.10 |
ENST00000301180.5
|
DIP2B
|
DIP2 disco-interacting protein 2 homolog B (Drosophila) |
| chr17_+_43213004 | 1.09 |
ENST00000586346.1
ENST00000398322.3 ENST00000592162.1 ENST00000376955.4 ENST00000321854.8 |
ACBD4
|
acyl-CoA binding domain containing 4 |
| chr8_-_27850141 | 1.09 |
ENST00000524352.1
|
SCARA5
|
scavenger receptor class A, member 5 (putative) |
| chr19_-_1848451 | 1.08 |
ENST00000170168.4
|
REXO1
|
REX1, RNA exonuclease 1 homolog (S. cerevisiae) |
| chr7_+_112120908 | 1.07 |
ENST00000439068.2
ENST00000312849.4 ENST00000429049.1 |
LSMEM1
|
leucine-rich single-pass membrane protein 1 |
| chr12_-_51663959 | 1.07 |
ENST00000604188.1
ENST00000398453.3 |
SMAGP
|
small cell adhesion glycoprotein |
| chr3_+_58291965 | 1.06 |
ENST00000445193.3
ENST00000295959.5 ENST00000466547.1 |
RPP14
|
ribonuclease P/MRP 14kDa subunit |
| chr17_-_34122596 | 1.06 |
ENST00000250144.8
|
MMP28
|
matrix metallopeptidase 28 |
| chr16_+_16326352 | 1.05 |
ENST00000399336.4
ENST00000263012.6 ENST00000538468.1 |
NOMO3
|
NODAL modulator 3 |
| chr1_-_211307315 | 1.05 |
ENST00000271751.4
|
KCNH1
|
potassium voltage-gated channel, subfamily H (eag-related), member 1 |
| chr3_-_142607740 | 1.04 |
ENST00000485766.1
|
PCOLCE2
|
procollagen C-endopeptidase enhancer 2 |
| chr6_+_151187074 | 1.04 |
ENST00000367308.4
|
MTHFD1L
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like |
| chr8_+_22022653 | 1.04 |
ENST00000354870.5
ENST00000397816.3 ENST00000306349.8 |
BMP1
|
bone morphogenetic protein 1 |
| chr8_+_42948641 | 1.03 |
ENST00000518991.1
ENST00000331373.5 |
POMK
|
protein-O-mannose kinase |
| chr7_+_73082152 | 1.03 |
ENST00000324941.4
ENST00000451519.1 |
VPS37D
|
vacuolar protein sorting 37 homolog D (S. cerevisiae) |
| chr8_+_22446763 | 1.03 |
ENST00000450780.2
ENST00000430850.2 ENST00000447849.1 |
AC037459.4
|
Uncharacterized protein |
| chr8_-_66474884 | 1.02 |
ENST00000520902.1
|
CTD-3025N20.2
|
CTD-3025N20.2 |
| chr16_-_69788816 | 1.02 |
ENST00000268802.5
|
NOB1
|
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) |
| chr19_-_14217672 | 1.02 |
ENST00000587372.1
|
PRKACA
|
protein kinase, cAMP-dependent, catalytic, alpha |
| chr6_-_131384373 | 1.01 |
ENST00000392427.3
ENST00000525271.1 ENST00000527411.1 |
EPB41L2
|
erythrocyte membrane protein band 4.1-like 2 |
| chr5_-_140998481 | 1.01 |
ENST00000518047.1
|
DIAPH1
|
diaphanous-related formin 1 |
| chr9_-_140317605 | 1.00 |
ENST00000479452.1
ENST00000465160.2 |
EXD3
|
exonuclease 3'-5' domain containing 3 |
| chr11_-_18127566 | 1.00 |
ENST00000532452.1
ENST00000530180.1 ENST00000300013.4 ENST00000529318.1 ENST00000524803.1 |
SAAL1
|
serum amyloid A-like 1 |
| chr18_-_48346298 | 0.99 |
ENST00000398439.3
|
MRO
|
maestro |
| chr2_-_132559234 | 0.99 |
ENST00000303798.2
|
C2orf27B
|
chromosome 2 open reading frame 27B |
| chr1_-_211307404 | 0.98 |
ENST00000367007.4
|
KCNH1
|
potassium voltage-gated channel, subfamily H (eag-related), member 1 |
| chr17_-_7518145 | 0.97 |
ENST00000250113.7
ENST00000571597.1 |
FXR2
|
fragile X mental retardation, autosomal homolog 2 |
| chr12_-_1058685 | 0.97 |
ENST00000397230.2
ENST00000542785.1 ENST00000544742.1 ENST00000536177.1 ENST00000539046.1 ENST00000541619.1 |
RAD52
|
RAD52 homolog (S. cerevisiae) |
| chr19_+_39903185 | 0.95 |
ENST00000409794.3
|
PLEKHG2
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 2 |
| chr20_+_30028322 | 0.95 |
ENST00000376309.3
|
DEFB123
|
defensin, beta 123 |
| chr6_-_131384412 | 0.95 |
ENST00000445890.2
ENST00000368128.2 ENST00000337057.3 |
EPB41L2
|
erythrocyte membrane protein band 4.1-like 2 |
| chr11_+_44117099 | 0.95 |
ENST00000533608.1
|
EXT2
|
exostosin glycosyltransferase 2 |
| chr8_+_24772455 | 0.95 |
ENST00000433454.2
|
NEFM
|
neurofilament, medium polypeptide |
| chr7_-_38389573 | 0.95 |
ENST00000390344.2
|
TRGV5
|
T cell receptor gamma variable 5 |
| chr9_+_103189660 | 0.94 |
ENST00000374886.3
|
MSANTD3
|
Myb/SANT-like DNA-binding domain containing 3 |
| chr7_-_19748640 | 0.94 |
ENST00000222567.5
|
TWISTNB
|
TWIST neighbor |
| chr2_-_166060571 | 0.94 |
ENST00000360093.3
|
SCN3A
|
sodium channel, voltage-gated, type III, alpha subunit |
| chr1_+_18081804 | 0.93 |
ENST00000375406.1
|
ACTL8
|
actin-like 8 |
| chr12_-_113573495 | 0.92 |
ENST00000446861.3
|
RASAL1
|
RAS protein activator like 1 (GAP1 like) |
| chr6_-_32806483 | 0.92 |
ENST00000374899.4
|
TAP2
|
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| chr10_-_103603677 | 0.90 |
ENST00000358038.3
|
KCNIP2
|
Kv channel interacting protein 2 |
| chr6_-_41703296 | 0.90 |
ENST00000373033.1
|
TFEB
|
transcription factor EB |
| chr20_-_4721314 | 0.90 |
ENST00000418528.1
ENST00000326539.2 ENST00000423718.2 |
PRNT
|
prion protein (testis specific) |
| chr16_-_18573396 | 0.89 |
ENST00000543392.1
ENST00000381474.3 ENST00000330537.6 |
NOMO2
|
NODAL modulator 2 |
| chr19_-_59030921 | 0.89 |
ENST00000354590.3
ENST00000596739.1 |
ZBTB45
|
zinc finger and BTB domain containing 45 |
| chr19_+_10982336 | 0.88 |
ENST00000344150.4
|
CARM1
|
coactivator-associated arginine methyltransferase 1 |
| chr16_+_71392616 | 0.88 |
ENST00000349553.5
ENST00000302628.4 ENST00000562305.1 |
CALB2
|
calbindin 2 |
| chr12_-_124018252 | 0.87 |
ENST00000376874.4
|
RILPL1
|
Rab interacting lysosomal protein-like 1 |
| chr16_+_66638567 | 0.87 |
ENST00000567572.1
|
CMTM3
|
CKLF-like MARVEL transmembrane domain containing 3 |
| chr17_-_72919317 | 0.86 |
ENST00000319642.1
|
USH1G
|
Usher syndrome 1G (autosomal recessive) |
| chr16_+_67678818 | 0.86 |
ENST00000334583.6
|
RLTPR
|
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing |
| chr18_-_48346415 | 0.86 |
ENST00000431965.2
ENST00000436348.2 |
MRO
|
maestro |
Network of associatons between targets according to the STRING database.
First level regulatory network of RAD21_SMC3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 11.8 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 1.1 | 3.3 | GO:2001035 | tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037) |
| 1.0 | 4.2 | GO:0009257 | 10-formyltetrahydrofolate biosynthetic process(GO:0009257) |
| 1.0 | 2.9 | GO:0030264 | nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) |
| 1.0 | 2.9 | GO:0000294 | nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) |
| 0.8 | 6.9 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.8 | 6.1 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.7 | 4.4 | GO:1903575 | cornified envelope assembly(GO:1903575) |
| 0.7 | 2.9 | GO:1904647 | response to rotenone(GO:1904647) |
| 0.7 | 2.1 | GO:1900126 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.7 | 2.0 | GO:0032827 | natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) |
| 0.6 | 3.0 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.6 | 1.8 | GO:0045362 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
| 0.6 | 1.8 | GO:1903248 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.6 | 1.7 | GO:0019285 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.5 | 4.8 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 0.5 | 2.1 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.5 | 3.6 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.5 | 1.5 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 0.5 | 4.0 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.5 | 3.8 | GO:0097461 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.5 | 1.4 | GO:0060489 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
| 0.4 | 1.3 | GO:0034970 | histone H3-R2 methylation(GO:0034970) |
| 0.4 | 2.6 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
| 0.4 | 1.3 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.4 | 5.6 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.4 | 7.1 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.4 | 1.2 | GO:0035854 | regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) |
| 0.4 | 1.1 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.4 | 9.4 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.3 | 1.0 | GO:0002476 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) |
| 0.3 | 0.9 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 0.3 | 1.3 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 0.3 | 3.1 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.3 | 1.5 | GO:1990834 | response to odorant(GO:1990834) |
| 0.3 | 1.5 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.3 | 3.4 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.3 | 2.0 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.3 | 2.4 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.3 | 1.1 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.3 | 4.3 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.3 | 1.1 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.3 | 1.8 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
| 0.3 | 0.3 | GO:0072319 | vesicle uncoating(GO:0072319) |
| 0.3 | 1.5 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.3 | 1.5 | GO:0032252 | secretory granule localization(GO:0032252) |
| 0.2 | 0.2 | GO:1903392 | negative regulation of adherens junction organization(GO:1903392) |
| 0.2 | 2.0 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.2 | 1.5 | GO:1903412 | response to bile acid(GO:1903412) |
| 0.2 | 1.7 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.2 | 0.5 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) |
| 0.2 | 1.6 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.2 | 2.9 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.2 | 1.1 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
| 0.2 | 1.5 | GO:0003383 | apical constriction(GO:0003383) |
| 0.2 | 0.9 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.2 | 1.3 | GO:2000819 | regulation of nucleotide-excision repair(GO:2000819) |
| 0.2 | 0.6 | GO:0044029 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.2 | 3.9 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.2 | 2.0 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.2 | 0.8 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 0.2 | 0.8 | GO:2000721 | positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721) |
| 0.2 | 1.3 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.2 | 19.4 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.2 | 0.9 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.2 | 3.7 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.2 | 1.7 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.2 | 0.7 | GO:1901490 | regulation of lymphangiogenesis(GO:1901490) |
| 0.2 | 1.9 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.2 | 0.8 | GO:1904098 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.2 | 4.4 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.2 | 2.2 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.2 | 2.4 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.2 | 3.3 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
| 0.2 | 3.2 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.2 | 0.3 | GO:0036166 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 0.2 | 1.2 | GO:0035290 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 0.1 | 1.1 | GO:0002870 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
| 0.1 | 0.6 | GO:2000569 | T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
| 0.1 | 0.7 | GO:0021633 | optic nerve structural organization(GO:0021633) |
| 0.1 | 0.4 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
| 0.1 | 0.5 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
| 0.1 | 2.0 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.1 | 1.0 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 0.1 | 4.3 | GO:1903846 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.1 | 0.4 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.1 | 0.5 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 3.0 | GO:0015012 | heparan sulfate proteoglycan biosynthetic process(GO:0015012) |
| 0.1 | 2.5 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.1 | 0.5 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.1 | 0.3 | GO:0060424 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) |
| 0.1 | 1.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.1 | 1.1 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.1 | 0.2 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.1 | 0.9 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.1 | 0.5 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 0.1 | 0.4 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.1 | 0.5 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
| 0.1 | 0.4 | GO:0060266 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) |
| 0.1 | 1.5 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.1 | 0.6 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 0.1 | 0.4 | GO:2000434 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.1 | 0.5 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.1 | 0.7 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.1 | 1.7 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.1 | 0.7 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 0.7 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.1 | 7.6 | GO:0010812 | negative regulation of cell-substrate adhesion(GO:0010812) |
| 0.1 | 4.9 | GO:0097435 | fibril organization(GO:0097435) |
| 0.1 | 0.5 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.1 | 2.3 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.1 | 0.5 | GO:0071316 | cellular response to nicotine(GO:0071316) |
| 0.1 | 0.7 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.1 | 0.6 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.1 | 0.2 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.1 | 0.3 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.1 | 0.3 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 0.5 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.1 | 1.1 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.1 | 1.0 | GO:0071374 | cellular response to parathyroid hormone stimulus(GO:0071374) |
| 0.1 | 0.4 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.1 | 0.6 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 1.5 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 0.1 | 0.4 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.1 | 0.8 | GO:1902074 | response to salt(GO:1902074) |
| 0.1 | 1.6 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.1 | 0.3 | GO:0046104 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 0.1 | 0.6 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 0.2 | GO:0071529 | cementum mineralization(GO:0071529) |
| 0.1 | 0.4 | GO:0036089 | cleavage furrow formation(GO:0036089) |
| 0.1 | 0.8 | GO:0035878 | nail development(GO:0035878) |
| 0.1 | 1.6 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 0.2 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 0.1 | 1.1 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.1 | 1.6 | GO:0034755 | iron ion transmembrane transport(GO:0034755) |
| 0.1 | 0.4 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.1 | 0.2 | GO:1903597 | negative regulation of gap junction assembly(GO:1903597) |
| 0.1 | 0.4 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.1 | 0.2 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
| 0.1 | 0.7 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.1 | 3.0 | GO:0006739 | NADP metabolic process(GO:0006739) |
| 0.1 | 0.7 | GO:0010310 | regulation of hydrogen peroxide metabolic process(GO:0010310) |
| 0.0 | 5.3 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 2.2 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.0 | 2.1 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 1.0 | GO:0060285 | cilium-dependent cell motility(GO:0060285) |
| 0.0 | 0.3 | GO:0014826 | cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826) |
| 0.0 | 0.6 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.0 | 2.6 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.0 | 1.7 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 1.8 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.0 | 1.0 | GO:1990830 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.0 | 2.0 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.2 | GO:0046108 | uridine metabolic process(GO:0046108) |
| 0.0 | 0.6 | GO:0045778 | positive regulation of ossification(GO:0045778) |
| 0.0 | 0.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.0 | 1.5 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.0 | 2.9 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.1 | GO:0070781 | response to biotin(GO:0070781) |
| 0.0 | 0.5 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 1.0 | GO:0039702 | viral budding via host ESCRT complex(GO:0039702) |
| 0.0 | 0.5 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.0 | 0.6 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.0 | 0.2 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.0 | 0.8 | GO:0014887 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.0 | 0.9 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.0 | 0.6 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.0 | 0.5 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.0 | 0.6 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 0.4 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.0 | 0.1 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 0.0 | 0.6 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 2.7 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 1.9 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.7 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 1.0 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.0 | 0.3 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.0 | 0.4 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.0 | 0.6 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.0 | 0.8 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.0 | 0.1 | GO:0019230 | metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283) proprioception(GO:0019230) |
| 0.0 | 2.6 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
| 0.0 | 0.3 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.0 | 0.2 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.0 | 0.5 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
| 0.0 | 0.3 | GO:0015697 | quaternary ammonium group transport(GO:0015697) regulation of appetite(GO:0032098) |
| 0.0 | 0.6 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 2.5 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.1 | GO:1901165 | negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165) |
| 0.0 | 2.4 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.8 | GO:0030818 | negative regulation of cAMP biosynthetic process(GO:0030818) |
| 0.0 | 1.0 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 1.4 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.0 | 0.2 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.0 | 0.1 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.0 | 7.9 | GO:0010506 | regulation of autophagy(GO:0010506) |
| 0.0 | 0.3 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.0 | 0.6 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 2.5 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
| 0.0 | 0.6 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
| 0.0 | 0.1 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.0 | 1.2 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.5 | GO:0006582 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
| 0.0 | 0.9 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.0 | 0.5 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.0 | 1.3 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
| 0.0 | 1.5 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.0 | 0.7 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
| 0.0 | 0.2 | GO:0060605 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
| 0.0 | 0.8 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.0 | 0.1 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 0.1 | GO:0045408 | regulation of interleukin-6 biosynthetic process(GO:0045408) |
| 0.0 | 1.0 | GO:0019233 | sensory perception of pain(GO:0019233) |
| 0.0 | 1.2 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.0 | 0.3 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.0 | 0.5 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 0.3 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.0 | 1.3 | GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) |
| 0.0 | 1.5 | GO:0050807 | regulation of synapse organization(GO:0050807) |
| 0.0 | 0.2 | GO:0051962 | positive regulation of nervous system development(GO:0051962) |
| 0.0 | 0.3 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 0.0 | 0.1 | GO:0019441 | tryptophan catabolic process to kynurenine(GO:0019441) |
| 0.0 | 0.1 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.9 | GO:0030833 | regulation of actin filament polymerization(GO:0030833) |
| 0.0 | 0.4 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 0.4 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.0 | 4.7 | GO:0032259 | methylation(GO:0032259) |
| 0.0 | 1.0 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 0.9 | GO:0016234 | inclusion body(GO:0016234) |
| 0.8 | 4.0 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.7 | 3.4 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.6 | 11.8 | GO:0032059 | muscle thin filament tropomyosin(GO:0005862) bleb(GO:0032059) |
| 0.6 | 7.3 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.4 | 2.9 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.3 | 2.3 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.3 | 1.3 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.3 | 6.9 | GO:0005861 | troponin complex(GO:0005861) |
| 0.2 | 7.7 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.2 | 2.1 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.2 | 0.9 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 0.2 | 2.9 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.2 | 1.5 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.2 | 24.4 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.2 | 1.5 | GO:0089701 | U2AF(GO:0089701) |
| 0.2 | 2.7 | GO:0008091 | spectrin(GO:0008091) |
| 0.2 | 0.5 | GO:0016938 | kinesin I complex(GO:0016938) |
| 0.2 | 1.7 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 1.4 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.2 | 0.5 | GO:0097124 | Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134) |
| 0.2 | 0.6 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.2 | 0.8 | GO:0034678 | integrin alpha8-beta1 complex(GO:0034678) |
| 0.2 | 2.0 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 1.3 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.1 | 2.0 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 1.0 | GO:0042825 | TAP complex(GO:0042825) |
| 0.1 | 2.3 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 1.6 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.1 | 0.7 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 9.9 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.1 | 0.6 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.1 | 0.3 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.1 | 1.6 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.1 | 0.5 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.1 | 1.3 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 1.0 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 0.9 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.1 | 0.4 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.1 | 1.1 | GO:0030681 | multimeric ribonuclease P complex(GO:0030681) |
| 0.1 | 4.9 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 1.0 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 0.7 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 1.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 5.2 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 1.5 | GO:0042641 | actomyosin(GO:0042641) |
| 0.1 | 0.9 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 5.0 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 1.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 1.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 0.7 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 1.8 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 2.9 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.1 | 1.8 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.1 | 4.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 1.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.1 | 0.7 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.0 | 0.7 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.0 | 0.9 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 2.4 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.4 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 0.2 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.0 | 0.2 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 0.5 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.0 | 5.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.6 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.2 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 0.0 | 0.3 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 0.4 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 0.6 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 1.2 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 0.6 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 2.5 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.4 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.5 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.2 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 2.7 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 0.2 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.0 | 0.6 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 4.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 1.7 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 3.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 12.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.9 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 0.3 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.5 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 2.2 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 5.2 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 0.2 | GO:0034706 | sodium channel complex(GO:0034706) |
| 0.0 | 0.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 1.7 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 0.6 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 5.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.3 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.4 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 0.0 | 4.8 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 3.5 | GO:0031674 | I band(GO:0031674) |
| 0.0 | 1.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.6 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.1 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 0.1 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 2.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.6 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 4.1 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 3.2 | GO:0005911 | cell-cell junction(GO:0005911) |
| 0.0 | 2.5 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 7.4 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 0.1 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.0 | 0.2 | GO:0005845 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.0 | 0.1 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 0.0 | 1.7 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 3.2 | GO:0005912 | adherens junction(GO:0005912) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.7 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 1.0 | 4.2 | GO:0004329 | formate-tetrahydrofolate ligase activity(GO:0004329) |
| 1.0 | 2.9 | GO:0017082 | mineralocorticoid receptor activity(GO:0017082) |
| 0.7 | 3.5 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.7 | 6.2 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.6 | 1.8 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 0.6 | 8.9 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.6 | 1.8 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.6 | 1.8 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.6 | 3.4 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.5 | 3.8 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.5 | 2.1 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.5 | 1.5 | GO:0004019 | adenylosuccinate synthase activity(GO:0004019) |
| 0.5 | 6.9 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.5 | 2.0 | GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) |
| 0.4 | 3.1 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.4 | 1.7 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.4 | 1.6 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.3 | 2.0 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.3 | 3.1 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.3 | 0.8 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 0.3 | 0.8 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.3 | 4.0 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.3 | 7.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.3 | 0.8 | GO:0050252 | retinol O-fatty-acyltransferase activity(GO:0050252) |
| 0.3 | 1.5 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.2 | 2.0 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.2 | 2.0 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.2 | 1.1 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.2 | 7.2 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.2 | 1.0 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.2 | 2.0 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.2 | 4.3 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.2 | 0.6 | GO:0052725 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 0.2 | 2.2 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.2 | 1.5 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.2 | 1.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.2 | 0.5 | GO:0036137 | kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) |
| 0.2 | 12.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.2 | 2.0 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.2 | 0.6 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 2.9 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 0.6 | GO:0035473 | lipase binding(GO:0035473) |
| 0.1 | 2.1 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.1 | 0.6 | GO:0035651 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 0.1 | 0.8 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.1 | 0.4 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.1 | 0.5 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 0.1 | 0.6 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.1 | 3.3 | GO:0036041 | long-chain fatty acid binding(GO:0036041) |
| 0.1 | 5.3 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.1 | 2.0 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.1 | 12.3 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 1.8 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 0.2 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.1 | 2.2 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 2.3 | GO:0016918 | retinal binding(GO:0016918) |
| 0.1 | 0.5 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 1.0 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 1.8 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 1.4 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.1 | 1.0 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.1 | 5.1 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 1.7 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 1.5 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 1.5 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.1 | 3.0 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 0.6 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.1 | 2.1 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 1.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 0.3 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 3.1 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 0.7 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.1 | 0.2 | GO:0061663 | NEDD8 ligase activity(GO:0061663) |
| 0.1 | 0.2 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 0.1 | 0.7 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.1 | 1.5 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 1.1 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 0.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.6 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 2.3 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 3.9 | GO:1990939 | ATP-dependent microtubule motor activity(GO:1990939) |
| 0.1 | 8.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.1 | 0.3 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 0.1 | 1.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 1.1 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.1 | 0.3 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.1 | 1.7 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.6 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 0.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 0.9 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.0 | 0.3 | GO:0005329 | dopamine transmembrane transporter activity(GO:0005329) |
| 0.0 | 1.0 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 2.4 | GO:0098632 | protein binding involved in cell-cell adhesion(GO:0098632) |
| 0.0 | 0.7 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.9 | GO:0005536 | glucose binding(GO:0005536) |
| 0.0 | 0.9 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 0.9 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 0.2 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.0 | 0.4 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 0.7 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 1.1 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 1.6 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.0 | 0.2 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 0.0 | 0.2 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.0 | 0.9 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 1.5 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 0.6 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 5.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 1.2 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.5 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.0 | 0.2 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.0 | 0.2 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.0 | 1.5 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.0 | 0.6 | GO:0005346 | adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216) |
| 0.0 | 0.6 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.3 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.0 | 13.2 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 2.0 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.1 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.0 | 2.9 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.2 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.0 | 0.2 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.5 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.7 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.3 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.0 | 0.4 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 17.5 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.8 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 6.1 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 0.4 | GO:0001163 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.0 | 0.1 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 0.0 | 0.6 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
| 0.0 | 0.2 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.0 | 5.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.7 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.5 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.0 | 0.5 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.0 | 1.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.1 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 0.0 | 1.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.6 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.0 | 0.2 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.0 | 1.3 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.3 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 0.8 | GO:0004521 | endoribonuclease activity(GO:0004521) |
| 0.0 | 0.1 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.0 | 0.5 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 0.2 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 0.8 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.4 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.4 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 0.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 0.4 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.0 | 1.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 3.3 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 1.1 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 2.4 | GO:0019902 | phosphatase binding(GO:0019902) |
| 0.0 | 0.4 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 1.4 | GO:0004527 | exonuclease activity(GO:0004527) |
| 0.0 | 0.8 | GO:0008375 | acetylglucosaminyltransferase activity(GO:0008375) |
| 0.0 | 0.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.2 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.3 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.0 | 1.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.1 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 0.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.1 | GO:0009374 | biotin binding(GO:0009374) |
| 0.0 | 0.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.5 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.6 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.5 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.0 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 0.0 | 0.2 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 0.8 | GO:0005518 | collagen binding(GO:0005518) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.0 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 4.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 7.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 5.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 2.6 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.1 | 5.2 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 2.0 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 3.1 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 7.5 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 4.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 1.6 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 5.9 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 2.6 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 0.3 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 0.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 1.0 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 1.5 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 0.7 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 1.9 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 8.8 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.4 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.4 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 3.5 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 2.3 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.9 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 0.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.8 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.8 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 0.9 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 1.0 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.0 | 1.1 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 7.4 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.4 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.3 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.5 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 1.8 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 6.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.2 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 2.1 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.8 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 0.5 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 1.7 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.5 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.1 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.2 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 22.7 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.3 | 21.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.2 | 5.6 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 3.7 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 1.0 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.1 | 4.7 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 1.3 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 1.9 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.1 | 0.4 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.1 | 0.8 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.1 | 2.1 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 1.2 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.1 | 1.6 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.1 | 4.6 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 1.5 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 1.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 1.6 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 3.2 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 4.9 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.4 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 2.0 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 2.0 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 0.1 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.1 | 3.5 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 2.0 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.1 | 3.3 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 1.3 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.0 | 3.4 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 0.4 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 1.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 1.5 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 2.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.5 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 3.8 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.7 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 3.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 1.0 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 0.2 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 5.0 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 1.0 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 1.0 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.7 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.3 | REACTOME FRS2 MEDIATED CASCADE | Genes involved in FRS2-mediated cascade |
| 0.0 | 0.6 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 2.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.6 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.0 | 1.0 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 1.5 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.6 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 1.1 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 5.4 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.0 | 1.1 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 0.3 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 1.8 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 0.0 | 0.2 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.0 | 0.3 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 3.3 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.6 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.7 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.0 | 0.8 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.2 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.0 | 0.7 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.6 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 0.1 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.0 | 1.1 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.7 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 0.5 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 0.5 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 1.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.4 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |