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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for RARA

Z-value: 0.73

Motif logo

Transcription factors associated with RARA

Gene Symbol Gene ID Gene Info
ENSG00000131759.13 retinoic acid receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARAhg19_v2_chr17_+_38474489_38474548-0.337.1e-02Click!

Activity profile of RARA motif

Sorted Z-values of RARA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_107078851 2.93 ENST00000390628.2
immunoglobulin heavy variable 1-58
chr3_+_13590636 2.26 ENST00000295760.7
fibulin 2
chr6_+_19837592 2.18 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr22_-_50970506 1.61 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr12_+_102091400 1.56 ENST00000229266.3
ENST00000549872.1
choline phosphotransferase 1
chr6_+_32709119 1.46 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr2_+_106682135 1.36 ENST00000437659.1
chromosome 2 open reading frame 40
chr19_-_6720686 1.18 ENST00000245907.6
complement component 3
chr16_-_55866997 1.11 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr1_+_18807424 0.96 ENST00000400664.1
kelch domain containing 7A
chr1_+_113933581 0.94 ENST00000307546.9
ENST00000369615.1
ENST00000369611.4
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr15_+_33010175 0.93 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
gremlin 1, DAN family BMP antagonist
chr5_-_16509101 0.86 ENST00000399793.2
family with sequence similarity 134, member B
chrX_-_8700171 0.86 ENST00000262648.3
Kallmann syndrome 1 sequence
chr17_+_14204389 0.84 ENST00000360954.2
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr22_+_23487513 0.84 ENST00000263116.2
ENST00000341989.4
RAB36, member RAS oncogene family
chr3_-_52486841 0.83 ENST00000496590.1
troponin C type 1 (slow)
chr14_-_21493884 0.82 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG family member 2
chr1_+_113933371 0.81 ENST00000369617.4
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr22_+_45072958 0.81 ENST00000403581.1
proline rich 5 (renal)
chr18_+_44526786 0.81 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chr22_+_45072925 0.81 ENST00000006251.7
proline rich 5 (renal)
chr12_-_122107549 0.78 ENST00000355329.3
MORN repeat containing 3
chr22_-_50970566 0.76 ENST00000405135.1
ENST00000401779.1
outer dense fiber of sperm tails 3B
chr19_-_821931 0.72 ENST00000359894.2
ENST00000520876.3
ENST00000519502.1
hsa-mir-3187
chr2_+_189157498 0.71 ENST00000359135.3
GULP, engulfment adaptor PTB domain containing 1
chr9_-_140009130 0.70 ENST00000497375.1
ENST00000371579.2
dipeptidyl-peptidase 7
chr19_+_35168567 0.69 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
zinc finger protein 302
chr14_-_21493649 0.69 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr9_+_131799213 0.69 ENST00000358369.4
ENST00000406926.2
ENST00000277475.5
ENST00000450073.1
family with sequence similarity 73, member B
chr1_-_109203648 0.69 ENST00000370031.1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr1_-_48937838 0.67 ENST00000371847.3
spermatogenesis associated 6
chr3_-_112218378 0.67 ENST00000334529.5
B and T lymphocyte associated
chr1_-_109203997 0.63 ENST00000370032.5
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr1_+_3607228 0.63 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
tumor protein p73
chr17_-_4463856 0.63 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
gamma-glutamyltransferase 6
chr15_+_90777424 0.62 ENST00000561433.1
ENST00000559204.1
ENST00000558291.1
GDP-D-glucose phosphorylase 1
chrX_-_99986494 0.62 ENST00000372989.1
ENST00000455616.1
ENST00000454200.2
ENST00000276141.6
synaptotagmin-like 4
chr19_+_35168633 0.61 ENST00000505365.2
zinc finger protein 302
chr20_+_43160409 0.59 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_-_109203685 0.59 ENST00000402983.1
ENST00000420055.1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr2_+_189157536 0.57 ENST00000409580.1
ENST00000409637.3
GULP, engulfment adaptor PTB domain containing 1
chr9_-_21994597 0.57 ENST00000579755.1
cyclin-dependent kinase inhibitor 2A
chr15_-_27018175 0.56 ENST00000311550.5
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr9_-_86432547 0.56 ENST00000376365.3
ENST00000376371.2
G kinase anchoring protein 1
chr10_-_44144292 0.54 ENST00000374433.2
zinc finger protein 32
chr16_+_3115378 0.54 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
interleukin 32
chr11_-_130184470 0.54 ENST00000357899.4
ENST00000397753.1
zinc finger and BTB domain containing 44
chr19_+_37342547 0.54 ENST00000331800.4
ENST00000586646.1
zinc finger protein 345
chr7_+_150065278 0.53 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr11_-_8985927 0.53 ENST00000528117.1
ENST00000309134.5
TMEM9 domain family, member B
chr1_+_43855560 0.53 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chr17_+_72428218 0.53 ENST00000392628.2
G protein-coupled receptor, family C, group 5, member C
chr11_+_63137251 0.52 ENST00000310969.4
ENST00000279178.3
solute carrier family 22 (organic anion transporter), member 9
chr14_-_90085458 0.52 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
forkhead box N3
chr6_-_31324943 0.52 ENST00000412585.2
ENST00000434333.1
major histocompatibility complex, class I, B
chrX_+_51486481 0.52 ENST00000340438.4
G1 to S phase transition 2
chr11_+_64073699 0.52 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr17_+_78075361 0.52 ENST00000577106.1
ENST00000390015.3
glucosidase, alpha; acid
chr11_-_8986474 0.52 ENST00000525069.1
TMEM9 domain family, member B
chr5_+_140019004 0.52 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
transmembrane and coiled-coil domains 6
chr9_-_21994344 0.51 ENST00000530628.2
ENST00000361570.3
cyclin-dependent kinase inhibitor 2A
chr5_-_135290705 0.51 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr19_-_12405689 0.49 ENST00000355684.5
zinc finger protein 44
chr17_-_80291818 0.49 ENST00000269389.3
ENST00000581691.1
secreted and transmembrane 1
chr19_+_17413663 0.49 ENST00000594999.1
mitochondrial ribosomal protein L34
chr10_-_44144152 0.47 ENST00000395797.1
zinc finger protein 32
chr6_-_146285455 0.47 ENST00000367505.2
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr11_-_8986279 0.46 ENST00000534025.1
TMEM9 domain family, member B
chr1_+_110036728 0.45 ENST00000369868.3
ENST00000430195.2
cytochrome b561 family, member D1
chr3_-_122512619 0.45 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr6_+_133562472 0.45 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
eyes absent homolog 4 (Drosophila)
chr16_+_2525110 0.45 ENST00000567020.1
ENST00000293970.5
TBC1 domain family, member 24
chr9_-_125027079 0.45 ENST00000417201.3
RNA binding motif protein 18
chr19_+_49661079 0.45 ENST00000355712.5
transient receptor potential cation channel, subfamily M, member 4
chr11_-_44971702 0.45 ENST00000533940.1
ENST00000533937.1
tumor protein p53 inducible protein 11
chr19_+_49661037 0.44 ENST00000427978.2
transient receptor potential cation channel, subfamily M, member 4
chr8_-_29120580 0.43 ENST00000524189.1
kinesin family member 13B
chr11_+_45944190 0.43 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
glycosyltransferase-like 1B
chr6_-_146285221 0.43 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr9_+_86595626 0.42 ENST00000445877.1
ENST00000325875.3
RecQ mediated genome instability 1
chr1_-_26633067 0.42 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBX domain protein 11
chr22_+_25465786 0.41 ENST00000401395.1
KIAA1671
chr11_-_17410869 0.41 ENST00000528731.1
potassium inwardly-rectifying channel, subfamily J, member 11
chr16_+_4838412 0.41 ENST00000589327.1
small integral membrane protein 22
chr1_-_154928562 0.41 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr7_+_89874524 0.41 ENST00000497910.1
chromosome 7 open reading frame 63
chr19_+_41305085 0.41 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr2_-_175351744 0.41 ENST00000295500.4
ENST00000392552.2
ENST00000392551.2
G protein-coupled receptor 155
chrX_+_55744228 0.41 ENST00000262850.7
Ras-related GTP binding B
chr1_+_107599267 0.40 ENST00000361318.5
ENST00000370078.1
protein arginine methyltransferase 6
chrX_+_55744166 0.40 ENST00000374941.4
ENST00000414239.1
Ras-related GTP binding B
chr7_+_89874483 0.40 ENST00000389297.4
ENST00000316089.8
chromosome 7 open reading frame 63
chr8_-_101348408 0.40 ENST00000519527.1
ENST00000522369.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr19_-_7764281 0.40 ENST00000360067.4
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr12_+_4758264 0.39 ENST00000266544.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr2_-_219433014 0.39 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr1_+_45965725 0.39 ENST00000401061.4
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr17_+_48172639 0.39 ENST00000503176.1
ENST00000503614.1
pyruvate dehydrogenase kinase, isozyme 2
chr19_-_1479117 0.39 ENST00000586564.1
ENST00000589529.1
ENST00000585675.1
ENST00000592872.1
ENST00000588871.1
ENST00000588427.1
ENST00000427685.2
chromosome 19 open reading frame 25
chr17_-_11900689 0.39 ENST00000322748.3
ENST00000454073.3
ENST00000580903.1
ENST00000580306.2
zinc finger protein 18
chr19_-_4540486 0.38 ENST00000306390.6
leucine-rich alpha-2-glycoprotein 1
chr19_-_12405606 0.38 ENST00000356109.5
zinc finger protein 44
chr10_+_81892347 0.38 ENST00000372267.2
placenta-specific 9
chr9_-_72374848 0.37 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
protein prenyltransferase alpha subunit repeat containing 1
chr1_-_48937821 0.37 ENST00000396199.3
spermatogenesis associated 6
chr22_-_21905750 0.37 ENST00000433039.1
RIMS binding protein 3C
chr1_+_222791417 0.37 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
melanoma inhibitory activity family, member 3
chrX_+_11129388 0.37 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr8_-_103136481 0.37 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
neurocalcin delta
chr16_+_31885079 0.37 ENST00000300870.10
ENST00000394846.3
zinc finger protein 267
chr3_-_88108192 0.36 ENST00000309534.6
CGG triplet repeat binding protein 1
chr14_+_54976603 0.36 ENST00000557317.1
cell growth regulator with ring finger domain 1
chr19_+_6373715 0.35 ENST00000599849.1
alkB, alkylation repair homolog 7 (E. coli)
chr17_-_61523622 0.35 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
cytochrome b561
chr5_-_55290773 0.35 ENST00000502326.3
ENST00000381298.2
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr8_-_57233103 0.35 ENST00000303749.3
ENST00000522671.1
short chain dehydrogenase/reductase family 16C, member 5
chr1_-_40367668 0.35 ENST00000397332.2
ENST00000429311.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr2_-_113191096 0.35 ENST00000496537.1
ENST00000330575.5
ENST00000302558.3
RANBP2-like and GRIP domain containing 8
chr1_-_59165763 0.35 ENST00000472487.1
Myb-like, SWIRM and MPN domains 1
chr16_+_4838393 0.34 ENST00000589721.1
small integral membrane protein 22
chr9_-_140095186 0.34 ENST00000409012.4
taperin
chr8_+_104152922 0.34 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
brain and acute leukemia, cytoplasmic
chr5_+_63461642 0.34 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
ring finger protein 180
chr16_+_56995762 0.34 ENST00000200676.3
ENST00000379780.2
cholesteryl ester transfer protein, plasma
chr19_+_17337406 0.33 ENST00000597836.1
occludin/ELL domain containing 1
chr10_+_60145155 0.33 ENST00000373895.3
transcription factor A, mitochondrial
chr12_+_112204691 0.33 ENST00000416293.3
ENST00000261733.2
aldehyde dehydrogenase 2 family (mitochondrial)
chr21_-_47738112 0.32 ENST00000417060.1
chromosome 21 open reading frame 58
chr1_-_48937682 0.32 ENST00000371843.3
spermatogenesis associated 6
chr9_+_139780942 0.32 ENST00000247668.2
ENST00000359662.3
TNF receptor-associated factor 2
chr5_-_157286104 0.32 ENST00000530742.1
ENST00000523908.1
ENST00000523094.1
ENST00000296951.5
ENST00000411809.2
clathrin interactor 1
chr2_+_108443388 0.32 ENST00000354986.4
ENST00000408999.3
RANBP2-like and GRIP domain containing 4
chr2_+_101179152 0.32 ENST00000264254.6
phosducin-like 3
chr5_-_137911049 0.31 ENST00000297185.3
heat shock 70kDa protein 9 (mortalin)
chr8_-_74659068 0.31 ENST00000523558.1
ENST00000521210.1
ENST00000355780.5
ENST00000524104.1
ENST00000521736.1
ENST00000521447.1
ENST00000517542.1
ENST00000521451.1
ENST00000521419.1
ENST00000518502.1
ENST00000524300.1
staufen double-stranded RNA binding protein 2
chr17_+_78075498 0.31 ENST00000302262.3
glucosidase, alpha; acid
chr12_+_133613878 0.31 ENST00000392319.2
ENST00000543758.1
zinc finger protein 84
chr10_+_115438920 0.31 ENST00000429617.1
ENST00000369331.4
caspase 7, apoptosis-related cysteine peptidase
chr22_+_29279552 0.31 ENST00000544604.2
zinc and ring finger 3
chr1_+_222988464 0.31 ENST00000420335.1
RP11-452F19.3
chr9_-_100935043 0.31 ENST00000343933.5
coronin, actin binding protein, 2A
chr12_+_50017184 0.31 ENST00000548825.2
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr14_+_73393040 0.30 ENST00000358377.2
ENST00000353777.3
ENST00000394234.2
ENST00000509153.1
ENST00000555042.1
DDB1 and CUL4 associated factor 4
chr22_-_24641027 0.30 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
gamma-glutamyltransferase 5
chr3_-_11623804 0.30 ENST00000451674.2
vestigial like 4 (Drosophila)
chr3_+_45067659 0.30 ENST00000296130.4
C-type lectin domain family 3, member B
chr9_-_135230336 0.29 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
senataxin
chr17_-_61523535 0.29 ENST00000584031.1
ENST00000392976.1
cytochrome b561
chr2_+_239229129 0.29 ENST00000391994.2
TNF receptor-associated factor 3 interacting protein 1
chr1_-_3816779 0.29 ENST00000361605.3
chromosome 1 open reading frame 174
chr4_+_76439665 0.29 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP domain containing 6
chr22_+_21737663 0.29 ENST00000434111.1
RIMS binding protein 3B
chr19_-_19144243 0.29 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr19_-_12595586 0.28 ENST00000397732.3
zinc finger protein 709
chr22_-_29663954 0.28 ENST00000216085.7
rhomboid domain containing 3
chr12_-_44152551 0.28 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr22_-_20461786 0.28 ENST00000426804.1
RIMS binding protein 3
chr8_-_57232656 0.28 ENST00000396721.2
short chain dehydrogenase/reductase family 16C, member 5
chr16_+_69985083 0.28 ENST00000288040.6
ENST00000449317.2
C-type lectin domain family 18, member A
chr9_+_124030338 0.28 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
gelsolin
chr9_+_114393581 0.28 ENST00000313525.3
DnaJ (Hsp40) homolog, subfamily C , member 25
chr2_+_238969530 0.28 ENST00000254663.6
ENST00000555827.1
ENST00000373332.3
ENST00000413463.1
ENST00000409736.2
ENST00000422984.2
ENST00000412508.1
ENST00000429612.2
selenocysteine lyase
chr2_+_223536428 0.28 ENST00000446656.3
monoacylglycerol O-acyltransferase 1
chr9_-_79009414 0.27 ENST00000376736.1
riboflavin kinase
chr3_-_101232019 0.27 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr16_+_71660052 0.27 ENST00000567566.1
MARVEL domain containing 3
chr15_+_72947079 0.27 ENST00000421285.3
golgin A6 family, member B
chr2_+_220071490 0.27 ENST00000409206.1
ENST00000409594.1
ENST00000289528.5
ENST00000422255.1
ENST00000409412.1
ENST00000409097.1
ENST00000409336.1
ENST00000409217.1
ENST00000409319.1
ENST00000444522.2
zinc finger, AN1-type domain 2B
chr4_-_85887503 0.27 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WD repeat and FYVE domain containing 3
chr1_-_33168336 0.27 ENST00000373484.3
syncoilin, intermediate filament protein
chr19_-_49926698 0.26 ENST00000270631.1
parathyroid hormone 2
chr1_+_9294822 0.26 ENST00000377403.2
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr9_+_125273081 0.26 ENST00000335302.5
olfactory receptor, family 1, subfamily J, member 2
chr16_-_3086927 0.26 ENST00000572449.1
coiled-coil domain containing 64B
chr8_+_67344710 0.26 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
alcohol dehydrogenase, iron containing, 1
chr4_-_107237374 0.25 ENST00000361687.4
ENST00000507696.1
ENST00000394708.2
ENST00000509532.1
TBC1 domain containing kinase
chr14_+_102027688 0.25 ENST00000510508.4
ENST00000359323.3
deiodinase, iodothyronine, type III
chr19_+_49956426 0.25 ENST00000293350.4
ENST00000540132.1
ENST00000455361.2
ENST00000433981.2
aldehyde dehydrogenase 16 family, member A1
chr16_+_71879861 0.24 ENST00000427980.2
ENST00000568581.1
ataxin 1-like
increased sodium tolerance 1 homolog (yeast)
chr1_-_43855479 0.24 ENST00000290663.6
ENST00000372457.4
mediator complex subunit 8
chr4_-_107237340 0.24 ENST00000394706.3
TBC1 domain containing kinase
chr5_+_31532373 0.24 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
chromosome 5 open reading frame 22
chr1_+_222988363 0.24 ENST00000450784.1
ENST00000426045.1
ENST00000457955.1
ENST00000444858.1
ENST00000435378.1
ENST00000441676.1
RP11-452F19.3
chr7_+_130794846 0.24 ENST00000421797.2
muskelin 1, intracellular mediator containing kelch motifs
chr3_-_126194707 0.24 ENST00000336332.5
ENST00000389709.3
ZXD family zinc finger C
chr7_+_152456829 0.24 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ARP3 actin-related protein 3 homolog B (yeast)
chr15_-_23692381 0.24 ENST00000567107.1
ENST00000345070.5
ENST00000312015.5
golgin A6 family-like 2
chrX_-_37706661 0.24 ENST00000432389.2
ENST00000378581.3
dynein, light chain, Tctex-type 3
chr16_+_3019246 0.23 ENST00000318782.8
ENST00000293978.8
progestin and adipoQ receptor family member IV
chr2_+_97203082 0.23 ENST00000454558.2
AT rich interactive domain 5A (MRF1-like)
chr5_+_112312416 0.23 ENST00000389063.2
decapping mRNA 2
chr16_+_3019552 0.23 ENST00000572687.1
progestin and adipoQ receptor family member IV
chr2_+_47630255 0.23 ENST00000406134.1
mutS homolog 2
chr4_+_154125565 0.23 ENST00000338700.5
tripartite motif containing 2
chr11_-_18610246 0.23 ENST00000379387.4
ENST00000541984.1
UEV and lactate/malate dehyrogenase domains
chr10_-_135238076 0.23 ENST00000414069.2
shadow of prion protein homolog (zebrafish)
chr22_+_21996549 0.23 ENST00000248958.4
stromal cell-derived factor 2-like 1
chr16_-_57219966 0.22 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
family with sequence similarity 192, member A
chr17_-_35969409 0.22 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
synergin, gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of RARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.4 1.7 GO:0002086 diaphragm contraction(GO:0002086)
0.4 1.2 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.4 1.6 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 0.9 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 1.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.2 0.9 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.2 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.5 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.1 0.4 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 0.4 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.5 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.5 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 1.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.4 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 1.0 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.1 1.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.3 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.3 GO:0015993 molecular hydrogen transport(GO:0015993)
0.1 1.4 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.2 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.3 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.5 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 1.1 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.2 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.2 GO:0061346 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.3 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.5 GO:0015747 urate transport(GO:0015747)
0.1 0.5 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.4 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.1 0.3 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.3 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 1.8 GO:0046710 GDP metabolic process(GO:0046710)
0.0 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.5 GO:0055091 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) phospholipid homeostasis(GO:0055091)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 4.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.2 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.8 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0097676 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.6 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.6 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.3 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.3 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808) negative regulation of hypersensitivity(GO:0002884)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.4 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.9 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.7 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.6 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.0 GO:0036090 cleavage furrow ingression(GO:0036090)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.1 GO:0022615 protein to membrane docking(GO:0022615) negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 2.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.0 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0097224 sperm connecting piece(GO:0097224)
0.2 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.4 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.8 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.3 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.9 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 1.6 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.5 GO:0042611 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.8 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.0 GO:0005713 recombination nodule(GO:0005713)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 0.8 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 1.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 0.5 GO:0017129 triglyceride binding(GO:0017129)
0.2 0.6 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.4 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.4 GO:0004915 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.5 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 1.4 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.3 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.9 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.3 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.8 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 2.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 1.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.2 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.4 GO:0019863 IgE binding(GO:0019863)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.5 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 1.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 2.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0070405 ammonium ion binding(GO:0070405)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis