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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for REL

Z-value: 1.22

Motif logo

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Transcription factors associated with REL

Gene Symbol Gene ID Gene Info
REL
ENSG00000162924.9 REL proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELhg19_v2_chr2_+_61108771_611087910.393.1e-02Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51471381 7.50 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr19_-_51471362 7.29 ENST00000376853.4
ENST00000424910.2
KLK6
kallikrein-related peptidase 6
chr2_+_228678550 4.82 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr19_-_51472031 4.82 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr2_-_113594279 4.79 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr7_+_107301065 4.33 ENST00000265715.3
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr18_+_21452964 4.13 ENST00000587184.1
LAMA3
laminin, alpha 3
chr18_+_21529811 3.89 ENST00000588004.1
LAMA3
laminin, alpha 3
chr4_-_74864386 3.85 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr11_-_58345569 3.45 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr18_+_21452804 3.28 ENST00000269217.6
LAMA3
laminin, alpha 3
chr9_-_136344197 3.23 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr12_-_95009837 3.04 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr19_+_41725088 2.90 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr2_+_102314161 2.89 ENST00000425019.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr12_-_76425368 2.88 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chrX_-_153599578 2.83 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr18_+_33877654 2.69 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr12_+_53491220 2.59 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr19_-_50143452 2.47 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr14_+_103589789 2.07 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr6_+_138188551 1.77 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_-_131384373 1.69 ENST00000392427.3
ENST00000525271.1
ENST00000527411.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr18_-_31802056 1.66 ENST00000538587.1
NOL4
nucleolar protein 4
chr20_+_42984330 1.65 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr5_+_150591678 1.62 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr11_+_102188224 1.61 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr19_+_41256764 1.57 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr8_+_70404996 1.57 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr6_-_131291572 1.56 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_+_87808725 1.51 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr2_-_220094031 1.45 ENST00000443140.1
ENST00000432520.1
ENST00000409618.1
ATG9A
autophagy related 9A
chr21_+_34775772 1.44 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr12_-_77272765 1.44 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
CSRP2
cysteine and glycine-rich protein 2
chr14_+_68086515 1.43 ENST00000261783.3
ARG2
arginase 2
chr1_-_8086343 1.43 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1
ERBB receptor feedback inhibitor 1
chr12_+_51632666 1.41 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr21_+_34775181 1.40 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr4_+_72897521 1.38 ENST00000308744.6
ENST00000344413.5
NPFFR2
neuropeptide FF receptor 2
chr10_+_17270214 1.37 ENST00000544301.1
VIM
vimentin
chr6_-_131384347 1.36 ENST00000530481.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_-_220094294 1.34 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
ATG9A
autophagy related 9A
chr21_+_34775698 1.33 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr3_+_101546827 1.32 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr1_-_6453426 1.31 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr14_-_35183886 1.30 ENST00000298159.6
CFL2
cofilin 2 (muscle)
chr10_+_104154229 1.24 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr11_+_102188272 1.21 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr11_-_128392085 1.21 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr14_-_53417732 1.20 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr7_-_98741714 1.20 ENST00000361125.1
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr8_-_105601134 1.19 ENST00000276654.5
ENST00000424843.2
LRP12
low density lipoprotein receptor-related protein 12
chr2_-_177502659 1.19 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr1_-_93426998 1.18 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr2_+_90077680 1.17 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr3_-_178789993 1.16 ENST00000432729.1
ZMAT3
zinc finger, matrin-type 3
chr10_+_89419370 1.14 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr7_-_98741642 1.13 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr18_-_31802282 1.13 ENST00000535475.1
NOL4
nucleolar protein 4
chr1_-_155959853 1.13 ENST00000462460.2
ENST00000368316.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr20_+_43803517 1.11 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr10_+_104155450 1.08 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr10_-_29923893 1.06 ENST00000355867.4
SVIL
supervillin
chr6_+_32121908 1.06 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr19_-_9879293 1.06 ENST00000397902.2
ENST00000592859.1
ENST00000588267.1
ZNF846
zinc finger protein 846
chr19_+_39390320 1.03 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr6_+_32121789 1.02 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr1_+_165796753 1.02 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr17_-_76356148 0.99 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chr12_+_53443680 0.99 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr1_-_27216729 0.98 ENST00000431781.2
ENST00000374135.4
GPN2
GPN-loop GTPase 2
chr8_-_49834299 0.98 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr8_-_49833978 0.97 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr14_-_69446034 0.96 ENST00000193403.6
ACTN1
actinin, alpha 1
chr14_-_106610852 0.96 ENST00000390603.2
IGHV3-15
immunoglobulin heavy variable 3-15
chrX_-_134186144 0.96 ENST00000370775.2
FAM127B
family with sequence similarity 127, member B
chr15_+_67430339 0.95 ENST00000439724.3
SMAD3
SMAD family member 3
chr1_-_209824643 0.92 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr16_+_27325202 0.91 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
IL4R
interleukin 4 receptor
chr17_+_26662730 0.91 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr12_+_53443963 0.91 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr10_+_30722866 0.90 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr4_-_74904398 0.87 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr19_+_41222998 0.87 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr2_-_74669009 0.84 ENST00000272430.5
RTKN
rhotekin
chr2_-_43453734 0.83 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr6_-_32821599 0.81 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr16_-_2059748 0.80 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr5_-_150460914 0.79 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr3_-_178790057 0.79 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr6_-_31774714 0.78 ENST00000375661.5
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_-_30080863 0.78 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr11_+_119039414 0.77 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLRX1
NLR family member X1
chr16_+_15737124 0.77 ENST00000396355.1
ENST00000396353.2
NDE1
nudE neurodevelopment protein 1
chr2_+_173940668 0.77 ENST00000375213.3
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr2_+_219745020 0.76 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr2_-_204400113 0.75 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr5_-_150466692 0.74 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr9_+_72658490 0.73 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr19_-_4831701 0.73 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr10_+_90750378 0.71 ENST00000355740.2
ENST00000352159.4
FAS
Fas cell surface death receptor
chr10_+_90750493 0.69 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chrX_+_115567767 0.69 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr19_-_50370509 0.69 ENST00000596014.1
PNKP
polynucleotide kinase 3'-phosphatase
chr2_+_204193149 0.68 ENST00000422511.2
ABI2
abl-interactor 2
chr10_+_102756800 0.66 ENST00000370223.3
LZTS2
leucine zipper, putative tumor suppressor 2
chr2_-_89247338 0.65 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr3_-_156878540 0.65 ENST00000461804.1
CCNL1
cyclin L1
chr20_-_43753104 0.65 ENST00000372785.3
WFDC12
WAP four-disulfide core domain 12
chr8_-_23712312 0.64 ENST00000290271.2
STC1
stanniocalcin 1
chr19_-_41256207 0.63 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr17_+_34640031 0.62 ENST00000339270.6
ENST00000482104.1
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr2_+_204193129 0.61 ENST00000417864.1
ABI2
abl-interactor 2
chr1_-_32110467 0.61 ENST00000440872.2
ENST00000373703.4
PEF1
penta-EF-hand domain containing 1
chr17_+_34639793 0.60 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr9_-_115095851 0.60 ENST00000343327.2
PTBP3
polypyrimidine tract binding protein 3
chr15_+_93447675 0.60 ENST00000536619.1
CHD2
chromodomain helicase DNA binding protein 2
chr6_+_142468383 0.59 ENST00000367621.1
ENST00000452973.2
VTA1
vesicle (multivesicular body) trafficking 1
chr12_-_56211485 0.58 ENST00000552080.1
ENST00000444631.2
ENST00000336133.3
SARNP
SAP domain containing ribonucleoprotein
chr5_+_14143728 0.58 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr3_+_47844615 0.58 ENST00000348968.4
DHX30
DEAH (Asp-Glu-Ala-His) box helicase 30
chr5_-_127418573 0.57 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3
CTC-228N24.3
chr20_-_33872518 0.57 ENST00000374436.3
EIF6
eukaryotic translation initiation factor 6
chr14_-_54955721 0.56 ENST00000554908.1
GMFB
glia maturation factor, beta
chr16_-_122619 0.56 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr3_-_53878644 0.56 ENST00000481668.1
ENST00000467802.1
CHDH
choline dehydrogenase
chr17_+_38474489 0.55 ENST00000394089.2
ENST00000425707.3
RARA
retinoic acid receptor, alpha
chr4_+_169418255 0.54 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr2_+_204193101 0.54 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
ABI2
abl-interactor 2
chr15_-_20193370 0.54 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr19_+_39390587 0.54 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr20_-_33872548 0.54 ENST00000374443.3
EIF6
eukaryotic translation initiation factor 6
chr1_-_29508321 0.54 ENST00000546138.1
SRSF4
serine/arginine-rich splicing factor 4
chr3_-_42744312 0.54 ENST00000416756.1
ENST00000441594.1
HHATL
hedgehog acyltransferase-like
chr3_-_49142504 0.54 ENST00000306125.6
ENST00000420147.2
QARS
glutaminyl-tRNA synthetase
chr6_-_29399744 0.53 ENST00000377154.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr19_-_17958771 0.51 ENST00000534444.1
JAK3
Janus kinase 3
chr12_-_49504655 0.50 ENST00000551782.1
ENST00000267102.8
LMBR1L
limb development membrane protein 1-like
chr4_-_76957214 0.50 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr5_+_82767284 0.50 ENST00000265077.3
VCAN
versican
chr10_-_97050777 0.50 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chrX_-_40594755 0.50 ENST00000324817.1
MED14
mediator complex subunit 14
chr1_-_204380919 0.50 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr13_-_52027134 0.50 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr15_-_89755034 0.50 ENST00000563254.1
RLBP1
retinaldehyde binding protein 1
chr3_-_49142178 0.50 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
QARS
glutaminyl-tRNA synthetase
chr11_-_7961141 0.49 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr2_-_191885686 0.49 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr19_+_41725140 0.48 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr10_+_13141585 0.48 ENST00000378764.2
OPTN
optineurin
chr17_-_45266542 0.47 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27
cell division cycle 27
chr2_+_68694678 0.47 ENST00000303795.4
APLF
aprataxin and PNKP like factor
chr17_+_7905912 0.47 ENST00000254854.4
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr11_-_65381643 0.46 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr1_-_231560790 0.46 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr2_+_90153696 0.46 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr15_+_26360970 0.45 ENST00000556159.1
ENST00000557523.1
LINC00929
long intergenic non-protein coding RNA 929
chr22_+_46546494 0.44 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
PPARA
peroxisome proliferator-activated receptor alpha
chr9_-_132805430 0.44 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chr1_-_113249948 0.43 ENST00000339083.7
ENST00000369642.3
RHOC
ras homolog family member C
chr2_-_68694390 0.42 ENST00000377957.3
FBXO48
F-box protein 48
chr1_-_27816556 0.41 ENST00000536657.1
WASF2
WAS protein family, member 2
chr12_+_56211703 0.41 ENST00000243045.5
ENST00000552672.1
ENST00000550836.1
ORMDL2
ORM1-like 2 (S. cerevisiae)
chr17_-_15469590 0.40 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr6_-_88299678 0.39 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr4_-_103749205 0.39 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr6_+_15401075 0.39 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr10_+_35894338 0.38 ENST00000321660.1
GJD4
gap junction protein, delta 4, 40.1kDa
chr14_-_30396948 0.38 ENST00000331968.5
PRKD1
protein kinase D1
chr2_+_131975882 0.38 ENST00000356920.5
ENST00000358087.5
POTEE
POTE ankyrin domain family, member E
chr22_+_22676808 0.37 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr5_+_49963239 0.37 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr2_+_228189941 0.36 ENST00000353339.3
ENST00000354503.6
ENST00000530359.1
ENST00000531278.1
ENST00000409565.1
ENST00000452930.1
ENST00000409616.1
ENST00000337110.7
ENST00000525195.1
ENST00000534203.1
ENST00000524634.1
ENST00000349901.7
MFF
mitochondrial fission factor
chr14_-_35873856 0.36 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr10_-_108924284 0.36 ENST00000344440.6
ENST00000263054.6
SORCS1
sortilin-related VPS10 domain containing receptor 1
chr6_-_32122106 0.35 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr16_+_31044812 0.35 ENST00000313843.3
STX4
syntaxin 4
chr11_-_104893863 0.35 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5
caspase 5, apoptosis-related cysteine peptidase
chr22_-_46659219 0.35 ENST00000253255.5
PKDREJ
polycystin (PKD) family receptor for egg jelly
chr2_+_162016827 0.34 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr2_-_27357479 0.34 ENST00000406567.3
ENST00000260643.2
PREB
prolactin regulatory element binding
chr7_+_102715315 0.34 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10
armadillo repeat containing 10
chr4_-_103749179 0.33 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr18_+_63418068 0.33 ENST00000397968.2
CDH7
cadherin 7, type 2
chr7_-_126892303 0.33 ENST00000358373.3
GRM8
glutamate receptor, metabotropic 8
chr16_-_62070305 0.33 ENST00000584337.1
CDH8
cadherin 8, type 2
chr9_-_139927462 0.32 ENST00000314412.6
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr19_-_39390440 0.32 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr11_+_19799327 0.32 ENST00000540292.1
NAV2
neuron navigator 2
chr12_+_123465033 0.31 ENST00000454885.2
ARL6IP4
ADP-ribosylation-like factor 6 interacting protein 4
chr9_-_136004782 0.30 ENST00000393157.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr5_+_133984462 0.30 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr9_-_115095883 0.29 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
PTBP3
polypyrimidine tract binding protein 3
chr9_-_115095123 0.28 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr10_-_6104253 0.28 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
IL2RA
interleukin 2 receptor, alpha
chr17_+_25799008 0.28 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr19_-_39390350 0.28 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr3_+_57261743 0.27 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr10_+_99609996 0.27 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr17_-_56492989 0.27 ENST00000583753.1
RNF43
ring finger protein 43

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.6 4.8 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.1 3.2 GO:0045210 FasL biosynthetic process(GO:0045210)
0.9 2.8 GO:0044805 late nucleophagy(GO:0044805)
0.9 19.0 GO:0016540 protein autoprocessing(GO:0016540)
0.8 2.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.6 1.9 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6 1.8 GO:0071947 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.6 2.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.5 3.4 GO:2000669 positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.5 4.3 GO:0015705 iodide transport(GO:0015705)
0.5 2.8 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.4 12.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 1.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 1.5 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 1.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.3 2.7 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.3 1.3 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.3 1.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.3 2.8 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.3 4.6 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 0.9 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.3 1.1 GO:0000103 sulfate assimilation(GO:0000103)
0.3 1.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.3 2.4 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.3 1.0 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 1.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 2.0 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 1.4 GO:0097527 Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527)
0.2 3.7 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.2 2.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 0.8 GO:0046967 cytosol to ER transport(GO:0046967)
0.2 0.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.6 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.2 0.6 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2 1.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 0.5 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.2 1.2 GO:0030578 PML body organization(GO:0030578)
0.1 1.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.7 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.8 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 4.5 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.7 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.4 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 1.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.4 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.6 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 2.1 GO:0051601 exocyst localization(GO:0051601)
0.1 3.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:0010887 negative regulation of cholesterol storage(GO:0010887) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.3 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.1 0.7 GO:1904417 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.1 0.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 1.4 GO:0000050 urea cycle(GO:0000050)
0.1 0.8 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 3.2 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 1.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.5 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.6 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110) regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.8 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 2.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.5 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 0.4 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.5 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.1 0.6 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.5 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 0.4 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.4 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.1 0.4 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.8 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.6 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.2 GO:0033622 integrin activation(GO:0033622)
0.0 1.1 GO:0007620 copulation(GO:0007620)
0.0 0.6 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 1.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.4 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 1.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.3 GO:0019935 cAMP-mediated signaling(GO:0019933) cyclic-nucleotide-mediated signaling(GO:0019935)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 3.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 1.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 1.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 12.2 GO:0005610 laminin-5 complex(GO:0005610)
0.9 2.8 GO:0031523 Myb complex(GO:0031523)
0.6 2.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.4 1.6 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3 4.6 GO:0008091 spectrin(GO:0008091)
0.3 2.6 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2 3.4 GO:0033643 host cell part(GO:0033643)
0.2 0.7 GO:0097342 ripoptosome(GO:0097342)
0.1 2.1 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.1 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.8 GO:0042825 TAP complex(GO:0042825)
0.1 0.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 5.4 GO:0002102 podosome(GO:0002102)
0.1 1.0 GO:0043219 lateral loop(GO:0043219)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 1.0 GO:0005916 fascia adherens(GO:0005916)
0.1 3.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 5.0 GO:0031526 brush border membrane(GO:0031526)
0.1 0.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 2.1 GO:0000145 exocyst(GO:0000145)
0.1 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 2.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 1.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0000346 transcription export complex(GO:0000346)
0.0 1.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 1.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 20.4 GO:0030141 secretory granule(GO:0030141)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.9 GO:0005795 Golgi stack(GO:0005795)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.9 4.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.8 4.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.7 2.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.5 4.6 GO:0042731 PH domain binding(GO:0042731)
0.4 1.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 2.9 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.0 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.3 0.9 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.3 1.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 1.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 2.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 3.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 2.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 4.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 0.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 3.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 1.4 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 0.7 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.2 2.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 1.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 2.3 GO:0048185 activin binding(GO:0048185)
0.1 0.8 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.0 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.4 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 21.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 2.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 1.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 2.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 2.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 2.1 GO:0000149 SNARE binding(GO:0000149)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 10.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 1.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 12.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 19.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 4.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 8.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 4.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 5.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 2.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 3.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 1.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 7.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 4.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 5.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 3.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 13.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 6.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 5.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 4.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 2.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation