Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
RFX3 Links Ensembl NCBI GeneCards UniProt	ENSG00000080298.11	regulatory factor X3
RFX2 Links Ensembl NCBI GeneCards UniProt	ENSG00000087903.8	regulatory factor X2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RFX2	hg19_v2_chr19_-_6110474_6110551	0.99	3.7e-24	Click!
RFX3	hg19_v2_chr9_-_3525968_3526016	0.97	6.3e-19	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr21_-_43916433 Show fit	273.94	ENST00000291536.3	RSPH1 Links Ensembl NCBI GeneCards UniProt Show fit	radial spoke head 1 homolog (Chlamydomonas)
chr21_-_43916296 Show fit	261.08	ENST00000398352.3	RSPH1 Links Ensembl NCBI GeneCards UniProt Show fit	radial spoke head 1 homolog (Chlamydomonas)
chr1_-_109656439 Show fit	229.02	ENST00000369949.4	C1orf194 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 194
chr1_-_159869912 Show fit	167.66	ENST00000368099.4	CCDC19 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 19
chr16_-_67427389 Show fit	155.73	ENST00000562206.1 ENST00000290942.5 ENST00000393957.2	TPPP3 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polymerization-promoting protein family member 3
chr1_+_151682909 Show fit	148.99	ENST00000326413.3 ENST00000442233.2	RIIAD1 Links Ensembl NCBI GeneCards UniProt Show fit AL589765.1 Links Ensembl NCBI GeneCards UniProt Show fit	regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr22_+_23487513 Show fit	139.51	ENST00000263116.2 ENST00000341989.4	RAB36 Links Ensembl NCBI GeneCards UniProt Show fit	RAB36, member RAS oncogene family
chr17_-_6735035 Show fit	138.16	ENST00000338694.2	TEKT1 Links Ensembl NCBI GeneCards UniProt Show fit	tektin 1
chr17_-_6735012 Show fit	137.77	ENST00000535086.1	TEKT1 Links Ensembl NCBI GeneCards UniProt Show fit	tektin 1
chr17_-_74137374 Show fit	133.39	ENST00000322957.6	FOXJ1 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box J1
chr15_+_71185148 Show fit	133.07	ENST00000443425.2 ENST00000560755.1	LRRC49 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 49
chr15_+_71184931 Show fit	132.91	ENST00000560369.1 ENST00000260382.5	LRRC49 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 49
chr2_+_228736321 Show fit	131.43	ENST00000309931.2	DAW1 Links Ensembl NCBI GeneCards UniProt Show fit	dynein assembly factor with WDR repeat domains 1
chr1_+_38022572 Show fit	128.44	ENST00000541606.1	DNALI1 Links Ensembl NCBI GeneCards UniProt Show fit	dynein, axonemal, light intermediate chain 1
chr6_+_43612750 Show fit	126.91	ENST00000372165.4 ENST00000372163.4	RSPH9 Links Ensembl NCBI GeneCards UniProt Show fit	radial spoke head 9 homolog (Chlamydomonas)
chr3_-_197676740 Show fit	120.49	ENST00000452735.1 ENST00000453254.1 ENST00000455191.1	IQCG Links Ensembl NCBI GeneCards UniProt Show fit	IQ motif containing G
chr3_-_50383096 Show fit	119.29	ENST00000442887.1 ENST00000360165.3	ZMYND10 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger, MYND-type containing 10
chr11_+_111385497 Show fit	118.24	ENST00000375618.4 ENST00000529167.1 ENST00000332814.6	C11orf88 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 88
chr2_+_228736335 Show fit	117.43	ENST00000440997.1 ENST00000545118.1	DAW1 Links Ensembl NCBI GeneCards UniProt Show fit	dynein assembly factor with WDR repeat domains 1
chr1_-_169396666 Show fit	116.93	ENST00000456107.1 ENST00000367805.3	CCDC181 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 181
chr1_+_38022513 Show fit	114.95	ENST00000296218.7	DNALI1 Links Ensembl NCBI GeneCards UniProt Show fit	dynein, axonemal, light intermediate chain 1
chr9_+_124922171 Show fit	113.42	ENST00000373764.3 ENST00000536616.1	MORN5 Links Ensembl NCBI GeneCards UniProt Show fit	MORN repeat containing 5
chr1_-_169396646 Show fit	112.79	ENST00000367806.3	CCDC181 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 181
chr2_-_130902567 Show fit	111.77	ENST00000457413.1 ENST00000392984.3 ENST00000409128.1 ENST00000441670.1 ENST00000409943.3 ENST00000409234.3 ENST00000310463.6	CCDC74B Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 74B
chr3_-_167098059 Show fit	110.20	ENST00000392764.1 ENST00000474464.1 ENST00000392766.2 ENST00000485651.1	ZBBX Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger, B-box domain containing
chr11_+_101918153 Show fit	109.21	ENST00000434758.2 ENST00000526781.1 ENST00000534360.1	C11orf70 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 70
chrX_-_48693955 Show fit	108.97	ENST00000218230.5	PCSK1N Links Ensembl NCBI GeneCards UniProt Show fit	proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_+_132285406 Show fit	108.32	ENST00000295171.6 ENST00000409856.3	CCDC74A Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 74A
chr7_+_48075108 Show fit	107.03	ENST00000420324.1 ENST00000435376.1 ENST00000430738.1 ENST00000348904.3 ENST00000539619.1	C7orf57 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 7 open reading frame 57
chr12_+_7014064 Show fit	101.80	ENST00000443597.2	LRRC23 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 23
chr1_+_217804661 Show fit	100.90	ENST00000366933.4	SPATA17 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 17
chr17_+_9479944 Show fit	100.40	ENST00000396219.3 ENST00000352665.5	WDR16 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 16
chrX_+_106449862 Show fit	95.95	ENST00000372453.3 ENST00000535523.1	PIH1D3 Links Ensembl NCBI GeneCards UniProt Show fit	PIH1 domain containing 3
chr1_+_151693984 Show fit	95.52	ENST00000479191.1	RIIAD1 Links Ensembl NCBI GeneCards UniProt Show fit	regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr8_-_49647791 Show fit	95.40	ENST00000262103.3 ENST00000523092.1 ENST00000433756.1	EFCAB1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 1
chr6_+_52285131 Show fit	95.10	ENST00000433625.2	EFHC1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain (C-terminal) containing 1
chr11_+_94245617 Show fit	93.13	ENST00000542198.1	RP11-867G2.2 Links Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 1171
chr12_+_7013897 Show fit	93.06	ENST00000007969.8 ENST00000323702.5	LRRC23 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 23
chr16_-_75590114 Show fit	91.09	ENST00000568377.1 ENST00000565067.1 ENST00000258173.6	TMEM231 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 231
chr12_-_58329819 Show fit	90.76	ENST00000551421.1	RP11-620J15.3 Links Ensembl NCBI GeneCards UniProt Show fit	RP11-620J15.3
chr11_-_75379612 Show fit	90.59	ENST00000526740.1	MAP6 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule-associated protein 6
chr15_+_82555125 Show fit	89.68	ENST00000566205.1 ENST00000339465.5 ENST00000569120.1 ENST00000566861.1	FAM154B Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 154, member B
chr12_+_7014126 Show fit	87.01	ENST00000415834.1 ENST00000436789.1	LRRC23 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 23
chr11_-_111944895 Show fit	86.83	ENST00000431456.1 ENST00000280350.4 ENST00000530641.1	PIH1D2 Links Ensembl NCBI GeneCards UniProt Show fit	PIH1 domain containing 2
chr11_-_111944704 Show fit	86.78	ENST00000532211.1	PIH1D2 Links Ensembl NCBI GeneCards UniProt Show fit	PIH1 domain containing 2
chr1_-_36916066 Show fit	86.62	ENST00000315643.9	OSCP1 Links Ensembl NCBI GeneCards UniProt Show fit	organic solute carrier partner 1
chr3_-_169530574 Show fit	85.47	ENST00000316515.7 ENST00000522830.1 ENST00000522526.2	LRRC34 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 34
chr6_+_116937636 Show fit	84.74	ENST00000368581.4 ENST00000229554.5 ENST00000368580.4	RSPH4A Links Ensembl NCBI GeneCards UniProt Show fit	radial spoke head 4 homolog A (Chlamydomonas)
chr3_-_169530452 Show fit	83.94	ENST00000446859.1	LRRC34 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 34
chr15_+_43803143 Show fit	83.18	ENST00000382031.1	MAP1A Links Ensembl NCBI GeneCards UniProt Show fit	microtubule-associated protein 1A
chr11_-_8615507 Show fit	81.69	ENST00000431279.2 ENST00000418597.1	STK33 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 33
chr16_+_84178874 Show fit	81.69	ENST00000378553.5	DNAAF1 Links Ensembl NCBI GeneCards UniProt Show fit	dynein, axonemal, assembly factor 1
chr6_+_112408768 Show fit	77.89	ENST00000368656.2 ENST00000604268.1	FAM229B Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 229, member B
chr15_+_81426588 Show fit	77.13	ENST00000286732.4	C15orf26 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 15 open reading frame 26
chr4_-_177116772 Show fit	76.43	ENST00000280191.2	SPATA4 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 4
chr6_-_109761707 Show fit	75.04	ENST00000520723.1 ENST00000518648.1 ENST00000417394.2	PPIL6 Links Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase (cyclophilin)-like 6
chr20_-_3762087 Show fit	72.98	ENST00000379756.3	SPEF1 Links Ensembl NCBI GeneCards UniProt Show fit	sperm flagellar 1
chr1_-_183622442 Show fit	72.76	ENST00000308641.4	APOBEC4 Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr2_+_74648848 Show fit	72.71	ENST00000409791.1 ENST00000426787.1 ENST00000348227.4	WDR54 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 54
chr16_+_58283814 Show fit	72.52	ENST00000443128.2 ENST00000219299.4	CCDC113 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 113
chr16_+_57728701 Show fit	71.22	ENST00000569375.1 ENST00000360716.3 ENST00000569167.1 ENST00000394337.4 ENST00000563126.1 ENST00000336825.8	CCDC135 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 135
chr16_+_67840986 Show fit	70.51	ENST00000561639.1 ENST00000567852.1 ENST00000565148.1 ENST00000388833.3 ENST00000561654.1 ENST00000431934.2	TSNAXIP1 Links Ensembl NCBI GeneCards UniProt Show fit	translin-associated factor X interacting protein 1
chr1_+_111888890 Show fit	69.73	ENST00000369738.4	PIFO Links Ensembl NCBI GeneCards UniProt Show fit	primary cilia formation
chr1_+_111889212 Show fit	69.39	ENST00000369737.4	PIFO Links Ensembl NCBI GeneCards UniProt Show fit	primary cilia formation
chr16_+_67840668 Show fit	68.94	ENST00000415766.3	TSNAXIP1 Links Ensembl NCBI GeneCards UniProt Show fit	translin-associated factor X interacting protein 1
chr1_-_67390474 Show fit	68.31	ENST00000371023.3 ENST00000371022.3 ENST00000371026.3 ENST00000431318.1	WDR78 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 78
chr15_-_55790515 Show fit	67.24	ENST00000448430.2 ENST00000457155.2	DYX1C1 Links Ensembl NCBI GeneCards UniProt Show fit	dyslexia susceptibility 1 candidate 1
chr3_-_107941209 Show fit	67.00	ENST00000492106.1	IFT57 Links Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 57 homolog (Chlamydomonas)
chr14_+_74486043 Show fit	66.81	ENST00000464394.1 ENST00000394009.3	CCDC176 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 176
chr6_-_165723088 Show fit	66.73	ENST00000230301.8	C6orf118 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 6 open reading frame 118
chr1_+_109656719 Show fit	66.23	ENST00000457623.2 ENST00000529753.1	KIAA1324 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA1324
chr10_+_63422695 Show fit	66.17	ENST00000330194.2 ENST00000389639.3	C10orf107 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 10 open reading frame 107
chr6_+_52285046 Show fit	66.06	ENST00000371068.5	EFHC1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain (C-terminal) containing 1
chr6_-_43478239 Show fit	65.09	ENST00000372441.1	LRRC73 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 73
chr7_+_76751926 Show fit	63.96	ENST00000285871.4 ENST00000431197.1	CCDC146 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 146
chr10_-_25305011 Show fit	63.90	ENST00000331161.4 ENST00000376363.1	ENKUR Links Ensembl NCBI GeneCards UniProt Show fit	enkurin, TRPC channel interacting protein
chr1_+_161068179 Show fit	63.65	ENST00000368011.4 ENST00000392192.2	KLHDC9 Links Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 9
chr1_-_36915880 Show fit	63.63	ENST00000445843.3	OSCP1 Links Ensembl NCBI GeneCards UniProt Show fit	organic solute carrier partner 1
chr13_+_31506818 Show fit	63.57	ENST00000380473.3	TEX26 Links Ensembl NCBI GeneCards UniProt Show fit	testis expressed 26
chr3_+_158288942 Show fit	63.54	ENST00000491767.1 ENST00000355893.5	MLF1 Links Ensembl NCBI GeneCards UniProt Show fit	myeloid leukemia factor 1
chr17_+_62075703 Show fit	63.35	ENST00000577953.1 ENST00000582540.1 ENST00000579184.1 ENST00000425164.3 ENST00000412177.1 ENST00000539996.1 ENST00000583891.1 ENST00000580752.1	C17orf72 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 17 open reading frame 72
chr3_+_158288960 Show fit	62.26	ENST00000484955.1 ENST00000359117.5 ENST00000498592.1 ENST00000477042.1 ENST00000471745.1 ENST00000469452.1	MLF1 Links Ensembl NCBI GeneCards UniProt Show fit	myeloid leukemia factor 1
chr15_-_68497657 Show fit	62.15	ENST00000448060.2 ENST00000467889.1	CALML4 Links Ensembl NCBI GeneCards UniProt Show fit	calmodulin-like 4
chr12_-_58329888 Show fit	62.13	ENST00000546580.1	RP11-620J15.3 Links Ensembl NCBI GeneCards UniProt Show fit	RP11-620J15.3
chr1_-_114301755 Show fit	60.97	ENST00000393357.2 ENST00000369596.2 ENST00000446739.1	PHTF1 Links Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 1
chr1_+_245133278 Show fit	60.24	ENST00000366522.2	EFCAB2 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 2
chr9_+_135754263 Show fit	60.02	ENST00000356311.5 ENST00000350499.6	C9orf9 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 9 open reading frame 9
chr10_+_22634384 Show fit	59.58	ENST00000376624.3 ENST00000376603.2 ENST00000376601.1 ENST00000538630.1 ENST00000456231.2 ENST00000313311.6 ENST00000435326.1	SPAG6 Links Ensembl NCBI GeneCards UniProt Show fit	sperm associated antigen 6
chr16_-_30773372 Show fit	59.52	ENST00000545825.1 ENST00000541260.1	C16orf93 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 16 open reading frame 93
chr7_-_100965011 Show fit	59.51	ENST00000498704.2 ENST00000517481.1 ENST00000437644.2 ENST00000315322.4	RABL5 Links Ensembl NCBI GeneCards UniProt Show fit	RAB, member RAS oncogene family-like 5
chr17_+_7761301 Show fit	59.49	ENST00000332439.4 ENST00000570446.1	CYB5D1 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 domain containing 1
chr11_+_61276214 Show fit	58.91	ENST00000378075.2	LRRC10B Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 10B
chr7_+_138818490 Show fit	58.16	ENST00000430935.1 ENST00000495038.1 ENST00000474035.2 ENST00000478836.2 ENST00000464848.1 ENST00000343187.4	TTC26 Links Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 26
chr2_+_39103103 Show fit	56.70	ENST00000340556.6 ENST00000410014.1 ENST00000409665.1 ENST00000409077.2 ENST00000409131.2	MORN2 Links Ensembl NCBI GeneCards UniProt Show fit	MORN repeat containing 2
chr1_-_36916011 Show fit	56.54	ENST00000356637.5 ENST00000354267.3 ENST00000235532.5	OSCP1 Links Ensembl NCBI GeneCards UniProt Show fit	organic solute carrier partner 1
chr3_+_97483572 Show fit	55.90	ENST00000335979.2 ENST00000394206.1	ARL6 Links Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosylation factor-like 6
chr6_+_109169591 Show fit	55.82	ENST00000368972.3 ENST00000392644.4	ARMC2 Links Ensembl NCBI GeneCards UniProt Show fit	armadillo repeat containing 2
chr3_+_158288999 Show fit	55.53	ENST00000482628.1 ENST00000478894.2 ENST00000392822.3 ENST00000466246.1	MLF1 Links Ensembl NCBI GeneCards UniProt Show fit	myeloid leukemia factor 1
chr17_+_260097 Show fit	54.98	ENST00000360127.6 ENST00000571106.1 ENST00000491373.1	C17orf97 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 17 open reading frame 97
chr11_-_8615720 Show fit	54.46	ENST00000358872.3 ENST00000454443.2	STK33 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 33
chr1_+_109656579 Show fit	54.39	ENST00000526264.1 ENST00000369939.3	KIAA1324 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA1324
chr19_-_55677999 Show fit	53.99	ENST00000532817.1 ENST00000527223.2 ENST00000391720.4	DNAAF3 Links Ensembl NCBI GeneCards UniProt Show fit	dynein, axonemal, assembly factor 3
chr12_+_122356488 Show fit	53.94	ENST00000397454.2	WDR66 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 66
chr11_-_8615488 Show fit	53.92	ENST00000315204.1 ENST00000396672.1 ENST00000396673.1	STK33 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 33
chr3_+_97483366 Show fit	53.66	ENST00000463745.1 ENST00000462412.1	ARL6 Links Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosylation factor-like 6
chr19_-_55677920 Show fit	53.62	ENST00000524407.2 ENST00000526003.1 ENST00000534170.1	DNAAF3 Links Ensembl NCBI GeneCards UniProt Show fit	dynein, axonemal, assembly factor 3
chrX_+_119030118 Show fit	52.59	ENST00000371422.1 ENST00000334356.2	AKAP14 Links Ensembl NCBI GeneCards UniProt Show fit	A kinase (PRKA) anchor protein 14
chr3_-_129147432 Show fit	51.58	ENST00000503957.1 ENST00000505956.1 ENST00000326085.3	EFCAB12 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 12
chr1_-_48937838 Show fit	51.39	ENST00000371847.3	SPATA6 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 6
chr1_-_118727781 Show fit	51.25	ENST00000336338.5	SPAG17 Links Ensembl NCBI GeneCards UniProt Show fit	sperm associated antigen 17
chr1_-_114302086 Show fit	50.72	ENST00000369604.1 ENST00000357783.2	PHTF1 Links Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 1
chrX_+_119029800 Show fit	50.40	ENST00000371431.3 ENST00000371423.2 ENST00000371425.4 ENST00000394594.2	AKAP14 Links Ensembl NCBI GeneCards UniProt Show fit	A kinase (PRKA) anchor protein 14
chr2_+_170335924 Show fit	49.83	ENST00000554017.1 ENST00000392663.2 ENST00000513963.1	BBS5 Links Ensembl NCBI GeneCards UniProt Show fit RP11-724O16.1 Links Ensembl NCBI GeneCards UniProt Show fit	Bardet-Biedl syndrome 5 Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr1_-_114301960 Show fit	49.69	ENST00000369598.1 ENST00000369600.1	PHTF1 Links Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 1
chr14_+_100259666 Show fit	49.26	ENST00000262233.6 ENST00000334192.4	EML1 Links Ensembl NCBI GeneCards UniProt Show fit	echinoderm microtubule associated protein like 1
chr3_-_47324079 Show fit	49.17	ENST00000352910.4	KIF9 Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 9
chr8_-_133687813 Show fit	49.15	ENST00000250173.1 ENST00000519595.1	LRRC6 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 6
chr22_-_38349552 Show fit	49.02	ENST00000422191.1 ENST00000249079.2 ENST00000418863.1 ENST00000403305.1 ENST00000403026.1	C22orf23 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 22 open reading frame 23
chr11_-_62473706 Show fit	48.47	ENST00000403550.1	BSCL2 Links Ensembl NCBI GeneCards UniProt Show fit	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_+_20512568 Show fit	47.67	ENST00000375099.3	UBXN10 Links Ensembl NCBI GeneCards UniProt Show fit	UBX domain protein 10
chr3_-_47324242 Show fit	47.40	ENST00000456548.1 ENST00000432493.1 ENST00000335044.2 ENST00000444589.2	KIF9 Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 9
chr3_-_107941230 Show fit	46.66	ENST00000264538.3	IFT57 Links Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 57 homolog (Chlamydomonas)
chr17_+_11501748 Show fit	46.50	ENST00000262442.4 ENST00000579828.1	DNAH9 Links Ensembl NCBI GeneCards UniProt Show fit	dynein, axonemal, heavy chain 9
chr2_+_120301997 Show fit	46.09	ENST00000602047.1	PCDP1 Links Ensembl NCBI GeneCards UniProt Show fit	Primary ciliary dyskinesia protein 1
chr18_+_44526786 Show fit	45.96	ENST00000245121.5 ENST00000356157.7	KATNAL2 Links Ensembl NCBI GeneCards UniProt Show fit	katanin p60 subunit A-like 2
chr19_-_7990991 Show fit	45.95	ENST00000318978.4	CTXN1 Links Ensembl NCBI GeneCards UniProt Show fit	cortexin 1
chr2_+_120302041 Show fit	45.80	ENST00000442513.3 ENST00000413369.3	PCDP1 Links Ensembl NCBI GeneCards UniProt Show fit	Primary ciliary dyskinesia protein 1
chr8_-_133687778 Show fit	45.72	ENST00000518642.1	LRRC6 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 6
chr3_-_47324008 Show fit	44.75	ENST00000425853.1	KIF9 Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 9
chr7_-_102715263 Show fit	44.47	ENST00000379305.3	FBXL13 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and leucine-rich repeat protein 13
chr1_-_114301503 Show fit	44.23	ENST00000447664.2	PHTF1 Links Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 1
chr1_-_173638976 Show fit	43.81	ENST00000333279.2	ANKRD45 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 45
chr7_-_102715172 Show fit	43.76	ENST00000456695.1 ENST00000455112.2 ENST00000440067.1	FBXL13 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and leucine-rich repeat protein 13
chr16_+_57406368 Show fit	43.57	ENST00000006053.6 ENST00000563383.1	CX3CL1 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-X3-C motif) ligand 1
chr3_-_57530051 Show fit	43.35	ENST00000311202.6 ENST00000351747.2 ENST00000495027.1 ENST00000389536.4	DNAH12 Links Ensembl NCBI GeneCards UniProt Show fit	dynein, axonemal, heavy chain 12
chr3_-_196439065 Show fit	42.89	ENST00000399942.4 ENST00000409690.3	CEP19 Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 19kDa
chr3_-_19975665 Show fit	42.36	ENST00000295824.9 ENST00000389256.4	EFHB Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain family, member B
chr16_+_4784458 Show fit	42.25	ENST00000590191.1	C16orf71 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 16 open reading frame 71
chr2_-_178483694 Show fit	42.23	ENST00000355689.5	TTC30A Links Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 30A
chr9_-_117111222 Show fit	42.18	ENST00000374079.4	AKNA Links Ensembl NCBI GeneCards UniProt Show fit	AT-hook transcription factor
chr18_-_71815051 Show fit	41.70	ENST00000582526.1 ENST00000419743.2	FBXO15 Links Ensembl NCBI GeneCards UniProt Show fit	F-box protein 15
chr17_-_56406117 Show fit	41.63	ENST00000268893.6 ENST00000355701.3	BZRAP1 Links Ensembl NCBI GeneCards UniProt Show fit	benzodiazepine receptor (peripheral) associated protein 1
chr18_+_77905894 Show fit	41.56	ENST00000589574.1 ENST00000588226.1 ENST00000585422.1	AC139100.2 Links Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr18_-_71814999 Show fit	41.47	ENST00000269500.5	FBXO15 Links Ensembl NCBI GeneCards UniProt Show fit	F-box protein 15
chr18_-_47792851 Show fit	40.57	ENST00000398545.4	CCDC11 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 11
chr11_-_62473776 Show fit	40.38	ENST00000278893.7 ENST00000407022.3 ENST00000421906.1	BSCL2 Links Ensembl NCBI GeneCards UniProt Show fit	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr22_-_38240412 Show fit	39.42	ENST00000215941.4	ANKRD54 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 54
chr2_-_230579185 Show fit	38.67	ENST00000341772.4	DNER Links Ensembl NCBI GeneCards UniProt Show fit	delta/notch-like EGF repeat containing
chr1_+_183605200 Show fit	38.64	ENST00000304685.4	RGL1 Links Ensembl NCBI GeneCards UniProt Show fit	ral guanine nucleotide dissociation stimulator-like 1
chr20_+_43160458 Show fit	38.52	ENST00000372889.1 ENST00000372887.1 ENST00000372882.3	PKIG Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr20_+_43160409 Show fit	38.02	ENST00000372894.3 ENST00000372892.3 ENST00000372891.3	PKIG Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr3_-_113160334 Show fit	37.14	ENST00000393845.2 ENST00000295868.2	WDR52 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 52
chr5_-_54529415 Show fit	36.81	ENST00000282572.4	CCNO Links Ensembl NCBI GeneCards UniProt Show fit	cyclin O
chr2_-_241497374 Show fit	36.29	ENST00000373318.2 ENST00000406958.1 ENST00000391987.1 ENST00000373320.4	ANKMY1 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and MYND domain containing 1
chr22_+_39052632 Show fit	36.13	ENST00000411557.1 ENST00000396811.2 ENST00000216029.3 ENST00000416285.1	CBY1 Links Ensembl NCBI GeneCards UniProt Show fit	chibby homolog 1 (Drosophila)
chr3_-_47324060 Show fit	35.69	ENST00000452770.2	KIF9 Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 9
chr8_+_144798429 Show fit	35.58	ENST00000338033.4 ENST00000395107.4 ENST00000395108.2	MAPK15 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 15
chr1_-_48937821 Show fit	35.40	ENST00000396199.3	SPATA6 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 6
chr1_+_63989004 Show fit	35.31	ENST00000371088.4	EFCAB7 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 7
chr21_-_40817645 Show fit	35.15	ENST00000438404.1 ENST00000358268.2 ENST00000411566.1 ENST00000451131.1 ENST00000418018.1 ENST00000415863.1 ENST00000426783.1 ENST00000288350.3 ENST00000485895.2 ENST00000448288.2 ENST00000456017.1 ENST00000434281.1	LCA5L Links Ensembl NCBI GeneCards UniProt Show fit	Leber congenital amaurosis 5-like
chr3_-_27410847 Show fit	35.04	ENST00000429845.2 ENST00000341435.5 ENST00000435750.1	NEK10 Links Ensembl NCBI GeneCards UniProt Show fit	NIMA-related kinase 10
chr9_-_135754164 Show fit	34.61	ENST00000298545.3	AK8 Links Ensembl NCBI GeneCards UniProt Show fit	adenylate kinase 8
chr10_+_104178946 Show fit	34.50	ENST00000432590.1	FBXL15 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and leucine-rich repeat protein 15
chr12_+_6930964 Show fit	34.49	ENST00000382315.3	GPR162 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 162
chr22_-_31063782 Show fit	34.20	ENST00000404885.1 ENST00000403268.1 ENST00000407308.1 ENST00000342474.4 ENST00000334679.3	DUSP18 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 18
chr15_+_67547163 Show fit	34.09	ENST00000335894.4	IQCH Links Ensembl NCBI GeneCards UniProt Show fit	IQ motif containing H
chr11_+_111807863 Show fit	34.06	ENST00000440460.2	DIXDC1 Links Ensembl NCBI GeneCards UniProt Show fit	DIX domain containing 1
chr1_-_169337176 Show fit	33.98	ENST00000472647.1 ENST00000367811.3	NME7 Links Ensembl NCBI GeneCards UniProt Show fit	NME/NM23 family member 7
chr1_-_24740207 Show fit	33.90	ENST00000003583.8 ENST00000337248.4	STPG1 Links Ensembl NCBI GeneCards UniProt Show fit	sperm-tail PG-rich repeat containing 1
chr3_+_119421849 Show fit	33.73	ENST00000273390.5 ENST00000463700.1	MAATS1 Links Ensembl NCBI GeneCards UniProt Show fit	MYCBP-associated, testis expressed 1
chr2_-_178417742 Show fit	33.54	ENST00000408939.3	TTC30B Links Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 30B
chr13_+_37005967 Show fit	33.43	ENST00000440264.1 ENST00000449823.1	CCNA1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin A1
chr3_-_113775328 Show fit	33.26	ENST00000483766.1 ENST00000545063.1 ENST00000491000.1 ENST00000295878.3	KIAA1407 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA1407
chr10_+_127585093 Show fit	33.17	ENST00000368695.1 ENST00000368693.1	FANK1 Links Ensembl NCBI GeneCards UniProt Show fit	fibronectin type III and ankyrin repeat domains 1
chr4_+_40751914 Show fit	32.98	ENST00000381782.2 ENST00000316607.5	NSUN7 Links Ensembl NCBI GeneCards UniProt Show fit	NOP2/Sun domain family, member 7
chr9_+_100069933 Show fit	32.34	ENST00000529487.1	CCDC180 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 180
chr9_-_131418944 Show fit	32.18	ENST00000419989.1 ENST00000451652.1 ENST00000372715.2	WDR34 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 34
chr21_-_34185944 Show fit	32.01	ENST00000479548.1	C21orf62 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 21 open reading frame 62
chr11_+_537494 Show fit	31.86	ENST00000270115.7	LRRC56 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 56
chr1_-_48937682 Show fit	31.12	ENST00000371843.3	SPATA6 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 6
chr7_+_133812052 Show fit	31.05	ENST00000285928.2	LRGUK Links Ensembl NCBI GeneCards UniProt Show fit	leucine-rich repeats and guanylate kinase domain containing
chr16_-_67450325 Show fit	30.96	ENST00000348579.2	ZDHHC1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger, DHHC-type containing 1
chr2_+_159651821 Show fit	30.89	ENST00000309950.3 ENST00000409042.1	DAPL1 Links Ensembl NCBI GeneCards UniProt Show fit	death associated protein-like 1
chr16_+_3550924 Show fit	30.82	ENST00000576634.1 ENST00000574369.1 ENST00000341633.5 ENST00000417763.2 ENST00000571025.1	CLUAP1 Links Ensembl NCBI GeneCards UniProt Show fit	clusterin associated protein 1
chr3_-_196045127 Show fit	30.47	ENST00000325318.5	TCTEX1D2 Links Ensembl NCBI GeneCards UniProt Show fit	Tctex1 domain containing 2
chr10_-_75118611 Show fit	30.31	ENST00000355577.3 ENST00000394865.1 ENST00000310715.3 ENST00000401621.2	TTC18 Links Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 18
chr11_-_8615687 Show fit	30.27	ENST00000534493.1 ENST00000422559.2	STK33 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 33
chr10_-_75118471 Show fit	29.99	ENST00000340329.3	TTC18 Links Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 18
chr19_-_55690758 Show fit	29.73	ENST00000590851.1	SYT5 Links Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin V
chr7_+_129142320 Show fit	29.65	ENST00000462322.2	SMKR1 Links Ensembl NCBI GeneCards UniProt Show fit	small lysine-rich protein 1
chr12_-_63328817 Show fit	29.56	ENST00000228705.6	PPM1H Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_+_109761898 Show fit	29.45	ENST00000258052.3	SMPD2 Links Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr19_-_41870026 Show fit	29.17	ENST00000243578.3	B9D2 Links Ensembl NCBI GeneCards UniProt Show fit	B9 protein domain 2
chr9_+_127615733 Show fit	29.08	ENST00000373574.1	WDR38 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 38
chr11_-_119252359 Show fit	29.08	ENST00000455332.2	USP2 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 2
chr7_+_102073966 Show fit	29.02	ENST00000495936.1 ENST00000356387.2 ENST00000478730.2 ENST00000468241.1 ENST00000403646.3	ORAI2 Links Ensembl NCBI GeneCards UniProt Show fit	ORAI calcium release-activated calcium modulator 2
chr19_-_50529193 Show fit	28.97	ENST00000596445.1 ENST00000599538.1	VRK3 Links Ensembl NCBI GeneCards UniProt Show fit	vaccinia related kinase 3
chr7_+_30811004 Show fit	28.67	ENST00000265299.6	FAM188B Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 188, member B
chr11_+_120894781 Show fit	28.60	ENST00000529397.1 ENST00000528512.1 ENST00000422003.2	TBCEL Links Ensembl NCBI GeneCards UniProt Show fit	tubulin folding cofactor E-like
chr17_+_7761013 Show fit	28.58	ENST00000571846.1	CYB5D1 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 domain containing 1

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View png image

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
44.5	133.4	GO:0002663	B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
28.7	114.9	GO:1903445	intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
27.8	305.4	GO:0060294	cilium movement involved in cell motility(GO:0060294)
26.7	855.1	GO:0044458	motile cilium assembly(GO:0044458)
19.1	938.2	GO:0035082	axoneme assembly(GO:0035082)
16.7	100.4	GO:0010732	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
14.5	43.6	GO:0050902	leukocyte adhesive activation(GO:0050902)
13.0	38.9	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
10.9	240.6	GO:0003341	cilium movement(GO:0003341)
10.7	96.1	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
8.0	24.0	GO:0061568	dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
7.5	30.0	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
7.2	122.5	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
7.1	352.6	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
6.5	52.3	GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
6.5	19.6	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
6.0	35.8	GO:1903575	cornified envelope assembly(GO:1903575)
6.0	23.8	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
5.5	49.4	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
5.2	57.4	GO:0042073	intraciliary transport(GO:0042073)
5.2	97.9	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
4.9	58.8	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
4.6	27.9	GO:0018095	protein polyglutamylation(GO:0018095)
4.4	167.3	GO:0071801	regulation of podosome assembly(GO:0071801)
3.8	33.9	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
3.7	22.1	GO:0001757	somite specification(GO:0001757)
3.6	28.4	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
3.5	56.6	GO:0045475	locomotor rhythm(GO:0045475)
3.5	21.2	GO:0070560	protein secretion by platelet(GO:0070560)
3.5	109.0	GO:0002021	response to dietary excess(GO:0002021)
3.5	42.0	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
3.3	156.9	GO:0048741	skeletal muscle fiber development(GO:0048741)
3.3	146.5	GO:0001578	microtubule bundle formation(GO:0001578)
3.2	25.7	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
3.2	19.2	GO:2001279	regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
3.0	6.1	GO:0098917	retrograde trans-synaptic signaling(GO:0098917)
3.0	24.3	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
3.0	21.0	GO:0007258	JUN phosphorylation(GO:0007258)
3.0	36.0	GO:0006228	UTP biosynthetic process(GO:0006228)
3.0	12.0	GO:1990262	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
3.0	11.9	GO:0035026	leading edge cell differentiation(GO:0035026)
2.9	309.2	GO:0007368	determination of left/right symmetry(GO:0007368)
2.8	11.4	GO:0070426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.8	11.2	GO:1902361	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.7	8.2	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
2.6	73.6	GO:0034389	lipid particle organization(GO:0034389)
2.6	18.4	GO:0044375	regulation of peroxisome size(GO:0044375)
2.5	7.4	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
2.4	14.5	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
2.4	74.6	GO:0007141	male meiosis I(GO:0007141)
2.4	9.6	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
2.4	9.6	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
2.4	21.3	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
2.3	9.3	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
2.3	31.7	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
2.1	34.2	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
2.1	29.0	GO:0002115	store-operated calcium entry(GO:0002115)
1.9	134.8	GO:0021795	cerebral cortex cell migration(GO:0021795)
1.9	44.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
1.8	3.7	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
1.8	5.5	GO:0002528	regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.8	17.8	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.7	8.7	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
1.7	33.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
1.7	5.2	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
1.6	33.4	GO:1904355	positive regulation of telomere capping(GO:1904355)
1.6	194.7	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
1.6	22.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
1.5	352.3	GO:0060271	cilium morphogenesis(GO:0060271)
1.4	28.6	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
1.4	18.5	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.4	27.4	GO:0042424	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
1.3	75.5	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
1.2	3.6	GO:0035552	oxidative single-stranded DNA demethylation(GO:0035552)
1.2	34.6	GO:0021591	ventricular system development(GO:0021591)
1.1	10.9	GO:0000160	phosphorelay signal transduction system(GO:0000160)
1.1	31.0	GO:0018345	protein palmitoylation(GO:0018345)
1.0	10.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
1.0	101.8	GO:0032418	lysosome localization(GO:0032418)
1.0	3.9	GO:0060849	radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
1.0	39.4	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
1.0	2.9	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.9	4.7	GO:1902903	regulation of fibril organization(GO:1902903) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.9	48.1	GO:0007405	neuroblast proliferation(GO:0007405)
0.9	8.2	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.9	3.6	GO:0072553	terminal button organization(GO:0072553)
0.8	3.4	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.8	34.5	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.8	8.4	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8	16.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.8	25.8	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.8	0.8	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.8	6.2	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.8	7.6	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.8	15.2	GO:2001222	regulation of neuron migration(GO:2001222)
0.8	22.5	GO:0007035	vacuolar acidification(GO:0007035)
0.7	0.7	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.7	22.8	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.7	3.5	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.7	100.8	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.7	4.8	GO:0070933	histone H4 deacetylation(GO:0070933)
0.7	89.7	GO:0007286	spermatid development(GO:0007286)
0.7	32.1	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.7	9.5	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.7	8.8	GO:0001302	replicative cell aging(GO:0001302)
0.7	8.0	GO:0015886	heme transport(GO:0015886)
0.6	5.8	GO:0032264	IMP salvage(GO:0032264)
0.6	7.8	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.6	8.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.6	42.7	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.6	8.0	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.6	16.9	GO:0006895	Golgi to endosome transport(GO:0006895)
0.6	16.2	GO:0001975	response to amphetamine(GO:0001975)
0.6	46.1	GO:0009060	aerobic respiration(GO:0009060)
0.6	6.3	GO:0032782	bile acid secretion(GO:0032782)
0.5	17.9	GO:0016574	histone ubiquitination(GO:0016574)
0.5	9.2	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.5	17.2	GO:0002437	inflammatory response to antigenic stimulus(GO:0002437)
0.5	7.2	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.5	25.6	GO:0006298	mismatch repair(GO:0006298)
0.5	63.7	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.4	10.8	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.4	1.3	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.4	52.4	GO:0022900	electron transport chain(GO:0022900)
0.4	4.1	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.4	4.8	GO:0002181	cytoplasmic translation(GO:0002181)
0.4	43.3	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.4	3.6	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.4	6.5	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.3	6.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.3	2.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.3	8.4	GO:0035357	peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.3	6.3	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.3	11.7	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.3	19.1	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.3	6.2	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.3	11.8	GO:0010107	potassium ion import(GO:0010107)
0.3	1.6	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3	2.6	GO:0090630	activation of GTPase activity(GO:0090630)
0.3	1.8	GO:1901315	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.3	91.9	GO:0000209	protein polyubiquitination(GO:0000209)
0.3	6.5	GO:0016578	histone deubiquitination(GO:0016578)
0.3	7.5	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2	4.2	GO:0008038	neuron recognition(GO:0008038)
0.2	10.7	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.2	6.6	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.2	3.4	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.2	10.8	GO:0015701	bicarbonate transport(GO:0015701)
0.2	4.7	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.2	80.4	GO:0007283	spermatogenesis(GO:0007283)
0.2	0.7	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.2	1.9	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.2	3.0	GO:0006004	fucose metabolic process(GO:0006004)
0.1	0.6	GO:0036490	regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1	2.7	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	3.3	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	9.8	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.1	2.2	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	67.7	GO:0031344	regulation of cell projection organization(GO:0031344)
0.1	21.8	GO:0045444	fat cell differentiation(GO:0045444)
0.1	2.7	GO:0021762	substantia nigra development(GO:0021762)
0.1	2.7	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.1	13.6	GO:0008285	negative regulation of cell proliferation(GO:0008285)
0.1	2.9	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.1	10.5	GO:1901796	regulation of signal transduction by p53 class mediator(GO:1901796)
0.1	0.9	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	1.8	GO:0035902	response to immobilization stress(GO:0035902)
0.1	0.3	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1	4.7	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.4	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	1.3	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	1.4	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0	0.7	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.8	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.3	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	1.0	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	1.0	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.2	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	1.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.8	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	1.3	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	1.0	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	1.6	GO:0016925	protein sumoylation(GO:0016925)
0.0	1.8	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.2	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.9	GO:0007218	neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
57.5	172.4	GO:0001534	radial spoke(GO:0001534)
54.5	381.3	GO:0002177	manchette(GO:0002177)
44.6	535.0	GO:0072687	meiotic spindle(GO:0072687)
31.9	159.4	GO:0005879	axonemal microtubule(GO:0005879)
29.5	117.9	GO:0097224	sperm connecting piece(GO:0097224)
21.6	64.8	GO:1990716	axonemal central apparatus(GO:1990716)
14.9	74.6	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
14.5	144.9	GO:0097427	microtubule bundle(GO:0097427)
13.6	395.7	GO:0030992	intraciliary transport particle B(GO:0030992)
11.9	226.5	GO:0036038	MKS complex(GO:0036038)
11.1	44.5	GO:0016939	kinesin II complex(GO:0016939)
10.2	30.5	GO:0031021	interphase microtubule organizing center(GO:0031021)
9.9	49.4	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
9.4	103.3	GO:0034464	BBSome(GO:0034464)
8.9	1002.2	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
8.5	245.7	GO:0034451	centriolar satellite(GO:0034451)
7.5	22.5	GO:0043291	RAVE complex(GO:0043291)
5.9	29.7	GO:1990769	proximal neuron projection(GO:1990769)
4.5	104.5	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
4.0	36.1	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
3.9	46.8	GO:0001520	outer dense fiber(GO:0001520)
3.8	206.8	GO:0009925	basal plasma membrane(GO:0009925)
3.5	49.7	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.8	238.3	GO:0036126	sperm flagellum(GO:0036126)
2.8	168.6	GO:0005801	cis-Golgi network(GO:0005801)
2.8	22.1	GO:0044294	dendritic growth cone(GO:0044294)
2.7	27.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
2.5	24.8	GO:1990023	mitotic spindle midzone(GO:1990023)
2.4	167.3	GO:0002102	podosome(GO:0002102)
2.2	2.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
2.2	20.0	GO:0097542	ciliary tip(GO:0097542)
2.1	164.2	GO:0036064	ciliary basal body(GO:0036064)
1.9	9.7	GO:0000138	Golgi trans cisterna(GO:0000138)
1.9	9.6	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
1.7	48.3	GO:0071682	endocytic vesicle lumen(GO:0071682)
1.5	11.9	GO:0035976	AP1 complex(GO:0035976)
1.4	110.5	GO:0005814	centriole(GO:0005814)
1.4	12.6	GO:0000137	Golgi cis cisterna(GO:0000137)
1.3	23.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
1.3	430.8	GO:0005929	cilium(GO:0005929)
1.2	21.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
1.2	8.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
1.1	87.0	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
1.1	24.0	GO:0044613	nuclear pore central transport channel(GO:0044613)
1.1	17.9	GO:0035102	PRC1 complex(GO:0035102)
1.1	15.9	GO:0072546	ER membrane protein complex(GO:0072546)
1.0	12.9	GO:0000242	pericentriolar material(GO:0000242)
0.8	88.6	GO:0001669	acrosomal vesicle(GO:0001669)
0.8	66.7	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.8	7.6	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.8	6.1	GO:0043196	varicosity(GO:0043196)
0.7	1.4	GO:0033565	ESCRT-0 complex(GO:0033565)
0.7	4.7	GO:0070847	core mediator complex(GO:0070847)
0.7	4.7	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.7	9.8	GO:0044232	organelle membrane contact site(GO:0044232)
0.6	6.5	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.6	285.7	GO:0005874	microtubule(GO:0005874)
0.6	2.6	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.6	105.8	GO:0031902	late endosome membrane(GO:0031902)
0.6	18.4	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.6	6.3	GO:0046581	intercellular canaliculus(GO:0046581)
0.5	23.4	GO:0035861	site of double-strand break(GO:0035861)
0.5	67.9	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.5	76.2	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.5	24.9	GO:0016235	aggresome(GO:0016235)
0.5	8.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.5	29.5	GO:0005901	caveola(GO:0005901)
0.4	7.8	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.4	4.8	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3	118.5	GO:0005813	centrosome(GO:0005813)
0.3	19.0	GO:0031201	SNARE complex(GO:0031201)
0.3	11.8	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.3	3.6	GO:0031143	pseudopodium(GO:0031143)
0.3	5.6	GO:0000421	autophagosome membrane(GO:0000421)
0.3	1.3	GO:1990761	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.3	28.0	GO:1902911	protein kinase complex(GO:1902911)
0.3	202.0	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.2	0.8	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2	25.2	GO:0030426	growth cone(GO:0030426)
0.2	1.8	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	2.7	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	11.3	GO:0032587	ruffle membrane(GO:0032587)
0.1	7.8	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	7.5	GO:0043202	lysosomal lumen(GO:0043202)
0.1	6.4	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	2.2	GO:0005771	multivesicular body(GO:0005771)
0.1	6.3	GO:0015030	Cajal body(GO:0015030)
0.1	1.0	GO:0017119	Golgi transport complex(GO:0017119)
0.1	15.4	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	1.0	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	40.0	GO:0044431	Golgi apparatus part(GO:0044431)
0.0	3.1	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	1.4	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	3.8	GO:0035579	specific granule membrane(GO:0035579)
0.0	2.5	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.9	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.8	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.2	GO:0061574	ASAP complex(GO:0061574)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
46.0	46.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
16.6	49.8	GO:0031862	prostanoid receptor binding(GO:0031862)
16.1	354.9	GO:0045504	dynein heavy chain binding(GO:0045504)
13.6	13.6	GO:0005119	smoothened binding(GO:0005119)
10.7	42.8	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
9.1	117.9	GO:0032027	myosin light chain binding(GO:0032027)
7.0	62.7	GO:0008158	hedgehog receptor activity(GO:0008158)
6.4	38.6	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
6.4	19.2	GO:0005136	interleukin-4 receptor binding(GO:0005136)
6.2	173.6	GO:0017160	Ral GTPase binding(GO:0017160)
5.9	35.4	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
5.5	227.1	GO:0043015	gamma-tubulin binding(GO:0043015)
4.9	34.6	GO:0004127	cytidylate kinase activity(GO:0004127)
4.6	36.8	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
4.5	17.8	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
4.1	114.3	GO:0045505	dynein intermediate chain binding(GO:0045505)
3.8	97.9	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
3.7	52.3	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
3.5	21.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
3.4	17.0	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
3.2	16.2	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
3.2	42.0	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
3.2	16.1	GO:0002046	opsin binding(GO:0002046)
3.2	31.8	GO:0004565	beta-galactosidase activity(GO:0004565)
3.1	70.7	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
3.1	39.9	GO:0034452	dynactin binding(GO:0034452)
3.0	27.4	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
3.0	12.0	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
2.8	30.6	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
2.7	8.2	GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
2.6	18.5	GO:0061649	ubiquitinated histone binding(GO:0061649)
2.5	7.5	GO:0003943	N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
2.3	63.7	GO:0070840	dynein complex binding(GO:0070840)
2.2	11.1	GO:0070568	guanylyltransferase activity(GO:0070568)
2.1	160.9	GO:0003777	microtubule motor activity(GO:0003777)
2.0	118.7	GO:0030544	Hsp70 protein binding(GO:0030544)
2.0	35.6	GO:0004707	MAP kinase activity(GO:0004707)
1.8	30.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.7	30.9	GO:0070513	death domain binding(GO:0070513)
1.6	9.6	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
1.6	406.9	GO:0008017	microtubule binding(GO:0008017)
1.6	14.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
1.6	10.9	GO:0004673	phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
1.5	44.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.5	78.6	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
1.4	11.2	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
1.4	36.8	GO:0005112	Notch binding(GO:0005112)
1.3	75.5	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
1.2	48.6	GO:0030332	cyclin binding(GO:0030332)
1.2	3.6	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
1.2	3.6	GO:0035514	DNA demethylase activity(GO:0035514)
1.1	49.8	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
1.0	43.6	GO:0048020	CCR chemokine receptor binding(GO:0048020)
1.0	31.0	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.0	2.9	GO:0015439	heme-transporting ATPase activity(GO:0015439)
1.0	2.9	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.9	16.0	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.9	96.0	GO:0051087	chaperone binding(GO:0051087)
0.9	2.7	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.9	24.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.9	31.7	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.9	32.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.8	58.6	GO:0015631	tubulin binding(GO:0015631)
0.8	35.8	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.8	48.6	GO:0017080	sodium channel regulator activity(GO:0017080)
0.7	8.0	GO:0019826	oxygen sensor activity(GO:0019826)
0.7	98.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.7	5.4	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.7	11.8	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.6	2.6	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.6	16.5	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.6	5.1	GO:0015232	heme transporter activity(GO:0015232)
0.6	11.9	GO:0035497	cAMP response element binding(GO:0035497)
0.6	19.7	GO:0030507	spectrin binding(GO:0030507)
0.6	6.5	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.6	2.9	GO:0004966	galanin receptor activity(GO:0004966)
0.6	1.7	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.5	5.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.5	10.8	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.5	42.7	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.5	457.5	GO:0005509	calcium ion binding(GO:0005509)
0.4	1.8	GO:0032408	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.4	37.1	GO:0019887	protein kinase regulator activity(GO:0019887)
0.4	4.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4	6.5	GO:0004526	ribonuclease P activity(GO:0004526)
0.4	4.8	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4	5.0	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.3	172.3	GO:0005525	GTP binding(GO:0005525)
0.3	6.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.3	2.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.3	19.7	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.3	7.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.3	6.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.3	30.1	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.3	10.9	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3	1.3	GO:0016417	S-acyltransferase activity(GO:0016417)
0.3	117.4	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3	1.3	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3	2.8	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	8.4	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.2	9.0	GO:0008536	Ran GTPase binding(GO:0008536)
0.2	2.2	GO:0004645	phosphorylase activity(GO:0004645)
0.2	0.4	GO:0015235	cobalamin transporter activity(GO:0015235)
0.2	1.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.2	39.5	GO:0005516	calmodulin binding(GO:0005516)
0.2	2.6	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2	1.3	GO:0048156	tau protein binding(GO:0048156)
0.2	4.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2	4.1	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1	5.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	3.9	GO:0001972	retinoic acid binding(GO:0001972)
0.1	16.9	GO:0043130	ubiquitin binding(GO:0043130)
0.1	5.3	GO:0035064	methylated histone binding(GO:0035064)
0.1	27.1	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.1	46.4	GO:0004857	enzyme inhibitor activity(GO:0004857)
0.1	75.7	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.1	20.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	59.9	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.1	8.5	GO:0016279	protein-lysine N-methyltransferase activity(GO:0016279)
0.1	14.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	6.4	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	2.7	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	0.8	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	1.7	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	1.6	GO:0003774	motor activity(GO:0003774)
0.1	7.8	GO:0051082	unfolded protein binding(GO:0051082)
0.1	1.2	GO:0008417	fucosyltransferase activity(GO:0008417)
0.1	160.2	GO:0003677	DNA binding(GO:0003677)
0.1	0.8	GO:0005537	mannose binding(GO:0005537)
0.1	3.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.1	7.3	GO:0000287	magnesium ion binding(GO:0000287)
0.0	704.2	GO:0003674	molecular_function(GO:0003674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	66.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.8	32.9	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.7	36.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.7	46.3	PID PLK1 PATHWAY	PLK1 signaling events
0.6	12.0	PID ALK2 PATHWAY	ALK2 signaling events
0.6	45.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.5	53.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.4	21.3	PID EPHA FWDPATHWAY	EPHA forward signaling
0.3	29.5	PID TNF PATHWAY	TNF receptor signaling pathway
0.3	18.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	19.5	PID P53 REGULATION PATHWAY	p53 pathway
0.3	12.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.2	8.0	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2	19.7	PID NOTCH PATHWAY	Notch signaling pathway
0.2	7.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.2	39.7	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.2	2.9	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	9.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	8.0	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.1	6.5	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.1	3.6	PID ARF6 PATHWAY	Arf6 signaling events
0.1	5.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	2.6	PID ATM PATHWAY	ATM pathway
0.1	2.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	3.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	1.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	4.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	3.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	1.3	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	1.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	5.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.7	PID BMP PATHWAY	BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	74.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
2.3	88.3	REACTOME KINESINS	Genes involved in Kinesins
2.1	38.6	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
1.6	32.9	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
1.6	31.7	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
1.5	25.7	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.4	19.6	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
1.3	35.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.8	8.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.7	20.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.7	42.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.7	43.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.5	51.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.4	6.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4	10.8	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.4	8.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4	11.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	2.6	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.3	10.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3	9.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	7.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.2	3.8	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2	8.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2	7.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2	8.0	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2	7.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.2	13.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	0.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	2.7	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	2.6	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	7.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	6.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	4.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	2.9	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	3.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	4.7	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	2.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	1.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	4.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	4.1	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	3.9	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	4.7	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	1.5	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter