Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for RREB1

Z-value: 1.29

Motif logo

Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
ENSG00000124782.15 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RREB1hg19_v2_chr6_+_7107830_71079930.271.5e-01Click!

Activity profile of RREB1 motif

Sorted Z-values of RREB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51471362 8.62 ENST00000376853.4
ENST00000424910.2
kallikrein-related peptidase 6
chr19_-_51471381 8.47 ENST00000594641.1
kallikrein-related peptidase 6
chr19_-_51456198 6.39 ENST00000594846.1
kallikrein-related peptidase 5
chr19_-_51456344 6.34 ENST00000336334.3
ENST00000593428.1
kallikrein-related peptidase 5
chr19_-_51456321 6.34 ENST00000391809.2
kallikrein-related peptidase 5
chr6_+_151646800 4.67 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chr18_-_21242774 4.45 ENST00000322980.9
ankyrin repeat domain 29
chr4_+_75230853 3.90 ENST00000244869.2
epiregulin
chr12_+_96588279 3.81 ENST00000552142.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr2_+_234104079 3.37 ENST00000417661.1
inositol polyphosphate-5-phosphatase, 145kDa
chr19_-_19051927 3.35 ENST00000600077.1
homer homolog 3 (Drosophila)
chr18_-_21242833 3.28 ENST00000586087.1
ENST00000592179.1
ankyrin repeat domain 29
chr19_-_19051993 2.97 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
homer homolog 3 (Drosophila)
chr16_-_4588762 2.92 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
cell death-inducing p53 target 1
chr1_-_17307173 2.75 ENST00000438542.1
ENST00000375535.3
microfibrillar-associated protein 2
chr10_+_17271266 2.74 ENST00000224237.5
vimentin
chr16_-_4588822 2.73 ENST00000564828.1
cell death-inducing p53 target 1
chr5_+_150591678 2.60 ENST00000523466.1
GM2 ganglioside activator
chr9_+_131174024 2.44 ENST00000420034.1
ENST00000372842.1
cerebral endothelial cell adhesion molecule
chr16_+_447226 2.36 ENST00000433358.1
NME/NM23 nucleoside diphosphate kinase 4
chr16_+_447209 2.34 ENST00000382940.4
ENST00000219479.2
NME/NM23 nucleoside diphosphate kinase 4
chr16_+_58533951 2.27 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG family member 4
chr11_+_69455855 2.23 ENST00000227507.2
ENST00000536559.1
cyclin D1
chrX_+_17755563 2.13 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
sex comb on midleg-like 1 (Drosophila)
chr16_-_4588469 2.13 ENST00000588381.1
ENST00000563332.2
cell death-inducing p53 target 1
chr10_-_121356518 2.05 ENST00000369092.4
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr17_+_1958388 2.03 ENST00000399849.3
hypermethylated in cancer 1
chr2_-_85637459 1.99 ENST00000409921.1
capping protein (actin filament), gelsolin-like
chr2_+_192543153 1.98 ENST00000425611.2
nucleic acid binding protein 1
chr7_-_24797032 1.96 ENST00000409970.1
ENST00000409775.3
deafness, autosomal dominant 5
chr18_+_33877654 1.92 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
formin homology 2 domain containing 3
chr8_-_144655141 1.90 ENST00000398882.3
maestro heat-like repeat family member 6
chr2_+_28618532 1.79 ENST00000545753.1
FOS-like antigen 2
chr10_-_71930222 1.74 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1 homolog A (S. cerevisiae)
chr17_-_39637392 1.73 ENST00000246639.2
ENST00000393989.1
keratin 35
chr19_-_39226045 1.69 ENST00000597987.1
ENST00000595177.1
calpain 12
chr17_-_39216344 1.66 ENST00000391418.2
keratin associated protein 2-3
chr20_+_58179582 1.60 ENST00000371015.1
ENST00000395639.4
phosphatase and actin regulator 3
chr7_-_102257139 1.54 ENST00000521076.1
ENST00000462172.1
ENST00000522801.1
ENST00000449970.2
ENST00000262940.7
RAS p21 protein activator 4
chr1_-_228604328 1.48 ENST00000355586.4
ENST00000366698.2
ENST00000520264.1
ENST00000479800.1
ENST00000295033.3
tripartite motif containing 17
chr8_+_32405785 1.47 ENST00000287842.3
neuregulin 1
chr1_-_6240183 1.47 ENST00000262450.3
ENST00000378021.1
chromodomain helicase DNA binding protein 5
chr17_-_73840415 1.42 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
unc-13 homolog D (C. elegans)
chr7_-_128045984 1.41 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr21_-_47648665 1.39 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr15_-_70390191 1.38 ENST00000559191.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr15_+_21145765 1.37 ENST00000553416.1
cancer/testis antigen 60 (non-protein coding)
chrX_+_134166333 1.35 ENST00000257013.7
family with sequence similarity 127, member A
chr12_-_8088871 1.31 ENST00000075120.7
solute carrier family 2 (facilitated glucose transporter), member 3
chr17_-_31620006 1.30 ENST00000225823.2
acid-sensing (proton-gated) ion channel 2
chr4_+_123747979 1.28 ENST00000608478.1
fibroblast growth factor 2 (basic)
chr2_+_192542850 1.25 ENST00000410026.2
nucleic acid binding protein 1
chr15_+_63481668 1.20 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B, member RAS oncogene family
chr8_-_142011036 1.19 ENST00000520892.1
protein tyrosine kinase 2
chr2_+_228337079 1.18 ENST00000409315.1
ENST00000373671.3
ENST00000409171.1
ArfGAP with FG repeats 1
chr20_-_36793663 1.17 ENST00000536701.1
ENST00000536724.1
transglutaminase 2
chr14_+_100070869 1.17 ENST00000502101.2
RP11-543C4.1
chr3_+_154797877 1.15 ENST00000462745.1
ENST00000493237.1
membrane metallo-endopeptidase
chr20_+_23168759 1.15 ENST00000411595.1
RP4-737E23.2
chr17_+_58499844 1.14 ENST00000269127.4
chromosome 17 open reading frame 64
chr9_+_35906176 1.12 ENST00000354323.2
histidine rich carboxyl terminus 1
chrX_-_119249819 1.12 ENST00000217999.2
Rhox homeobox family, member 1
chr1_-_161193349 1.12 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
apolipoprotein A-II
chr22_-_36357671 1.11 ENST00000408983.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr12_+_56415100 1.09 ENST00000547791.1
IKAROS family zinc finger 4 (Eos)
chr3_-_42744312 1.05 ENST00000416756.1
ENST00000441594.1
hedgehog acyltransferase-like
chr15_-_89764929 1.03 ENST00000268125.5
retinaldehyde binding protein 1
chr1_+_110091189 1.03 ENST00000369851.4
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr12_-_53074182 1.02 ENST00000252244.3
keratin 1
chr9_-_21994597 1.00 ENST00000579755.1
cyclin-dependent kinase inhibitor 2A
chr5_-_151304337 0.97 ENST00000455880.2
ENST00000545569.1
ENST00000274576.4
glycine receptor, alpha 1
chr14_+_105155925 0.97 ENST00000330634.7
ENST00000398337.4
ENST00000392634.4
inverted formin, FH2 and WH2 domain containing
chr12_-_49351148 0.96 ENST00000398092.4
ENST00000539611.1
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr12_-_120687948 0.95 ENST00000458477.2
paxillin
chr8_+_32406179 0.95 ENST00000405005.3
neuregulin 1
chrX_-_153881842 0.94 ENST00000369585.3
ENST00000247306.4
cancer/testis antigen 2
chr20_+_34700333 0.94 ENST00000441639.1
erythrocyte membrane protein band 4.1-like 1
chrX_+_151903207 0.92 ENST00000370287.3
chondrosarcoma associated gene 1
chr16_+_27325202 0.92 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
interleukin 4 receptor
chrX_+_47082408 0.91 ENST00000518022.1
ENST00000276052.6
cyclin-dependent kinase 16
chrX_+_153813407 0.91 ENST00000443287.2
ENST00000333128.3
cancer/testis antigen 1A
chr12_-_95044309 0.91 ENST00000261226.4
transmembrane and coiled-coil domain family 3
chr16_+_28889801 0.91 ENST00000395503.4
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr4_-_103940791 0.91 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr4_+_123747834 0.91 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr3_-_116163830 0.90 ENST00000333617.4
limbic system-associated membrane protein
chr19_-_18654293 0.89 ENST00000597547.1
ENST00000222308.4
ENST00000544835.3
ENST00000610101.1
ENST00000597960.3
ENST00000608443.1
FK506 binding protein 8, 38kDa
chr11_-_59436453 0.87 ENST00000300146.9
protein associated with topoisomerase II homolog 1 (yeast)
chr19_-_51336443 0.86 ENST00000598673.1
kallikrein-related peptidase 15
chr3_-_39196049 0.86 ENST00000514182.1
cysteine-serine-rich nuclear protein 1
chrX_+_151903253 0.86 ENST00000452779.2
ENST00000370291.2
chondrosarcoma associated gene 1
chr19_+_40973049 0.85 ENST00000598249.1
ENST00000338932.3
ENST00000344104.3
spectrin, beta, non-erythrocytic 4
chr21_-_36259445 0.84 ENST00000399240.1
runt-related transcription factor 1
chr22_-_51066521 0.81 ENST00000395621.3
ENST00000395619.3
ENST00000356098.5
ENST00000216124.5
ENST00000453344.2
ENST00000547307.1
ENST00000547805.1
arylsulfatase A
chr19_-_18653781 0.80 ENST00000596558.2
ENST00000453489.2
FK506 binding protein 8, 38kDa
chr22_-_37976082 0.80 ENST00000215886.4
lectin, galactoside-binding, soluble, 2
chr1_-_153363452 0.78 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chr16_+_28889703 0.78 ENST00000357084.3
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr17_-_39222131 0.77 ENST00000394015.2
keratin associated protein 2-4
chr2_-_101034070 0.76 ENST00000264249.3
carbohydrate sulfotransferase 10
chr4_+_190992087 0.76 ENST00000553598.1
double homeobox 4 like 7
chr3_+_186435137 0.76 ENST00000447445.1
kininogen 1
chr4_+_191005567 0.75 ENST00000605758.1
ENST00000554285.2
double homeobox 4
chr4_+_191012160 0.75 ENST00000553702.1
ENST00000554376.1
double homeobox 4 like 2
chr4_+_190998673 0.75 ENST00000554668.1
double homeobox 4 like 5
chr4_+_191005267 0.75 ENST00000556625.1
double homeobox 4
chr4_+_191011860 0.75 ENST00000440426.1
double homeobox 4 like 2
chr4_+_147560042 0.75 ENST00000281321.3
POU class 4 homeobox 2
chr4_+_190998973 0.75 ENST00000605696.1
ENST00000557283.2
double homeobox 4 like 5
chr4_+_191008560 0.75 ENST00000554690.1
double homeobox 4 like 3
chr12_-_12715266 0.74 ENST00000228862.2
dual specificity phosphatase 16
chrX_-_152939252 0.74 ENST00000340888.3
pregnancy up-regulated nonubiquitous CaM kinase
chr19_+_55477711 0.74 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
NLR family, pyrin domain containing 2
chr8_+_32406137 0.74 ENST00000521670.1
neuregulin 1
chr16_+_28834531 0.74 ENST00000570200.1
ataxin 2-like
chr19_+_55476620 0.74 ENST00000543010.1
ENST00000391721.4
ENST00000339757.7
NLR family, pyrin domain containing 2
chr3_-_48471454 0.73 ENST00000296440.6
ENST00000448774.2
plexin B1
chr9_-_21994344 0.73 ENST00000530628.2
ENST00000361570.3
cyclin-dependent kinase inhibitor 2A
chr9_-_34126730 0.73 ENST00000361264.4
DDB1 and CUL4 associated factor 12
chr11_-_71791435 0.72 ENST00000351960.6
ENST00000541719.1
ENST00000535111.1
nuclear mitotic apparatus protein 1
chr4_+_191008860 0.72 ENST00000605191.1
ENST00000557656.2
double homeobox 4 like 3
chr4_+_190995680 0.72 ENST00000605381.1
ENST00000553722.2
double homeobox 4 like 6
chr4_+_190995380 0.72 ENST00000555191.1
double homeobox 4 like 6
chrX_-_153847522 0.71 ENST00000328435.2
ENST00000359887.4
cancer/testis antigen 1B
chr19_-_51222707 0.71 ENST00000391814.1
SH3 and multiple ankyrin repeat domains 1
chr17_-_73840774 0.71 ENST00000207549.4
unc-13 homolog D (C. elegans)
chr7_-_92465868 0.70 ENST00000424848.2
cyclin-dependent kinase 6
chr19_-_15560730 0.70 ENST00000389282.4
ENST00000263381.7
widely interspaced zinc finger motifs
chr14_+_23563952 0.69 ENST00000319074.4
chromosome 14 open reading frame 119
chrX_+_151867214 0.69 ENST00000329342.5
ENST00000412733.1
ENST00000457643.1
melanoma antigen family A, 6
chrX_-_13752675 0.69 ENST00000380579.1
ENST00000458511.2
ENST00000519885.1
ENST00000358231.5
ENST00000518847.1
ENST00000453655.2
ENST00000359680.5
trafficking protein particle complex 2
chr7_-_752074 0.68 ENST00000360274.4
protein kinase, cAMP-dependent, regulatory, type I, beta
chr12_+_118454500 0.68 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
replication factor C (activator 1) 5, 36.5kDa
chr10_-_103603523 0.68 ENST00000370046.1
Kv channel interacting protein 2
chr17_-_77005860 0.67 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
calcium activated nucleotidase 1
chr8_-_60031762 0.67 ENST00000361421.1
thymocyte selection-associated high mobility group box
chr17_-_62658186 0.67 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr11_-_85779971 0.67 ENST00000393346.3
phosphatidylinositol binding clathrin assembly protein
chr17_+_15604513 0.66 ENST00000481540.1
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chrX_-_131352152 0.66 ENST00000342983.2
RAP2C, member of RAS oncogene family
chr11_+_46402744 0.65 ENST00000533952.1
midkine (neurite growth-promoting factor 2)
chrX_+_53078273 0.65 ENST00000332582.4
G protein-coupled receptor 173
chr2_-_32236002 0.65 ENST00000404530.1
mediator of cell motility 1
chr12_+_96588143 0.64 ENST00000228741.3
ENST00000547249.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr11_-_71791518 0.63 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
nuclear mitotic apparatus protein 1
chr8_-_22550815 0.63 ENST00000317216.2
early growth response 3
chr12_-_129570545 0.63 ENST00000389441.4
transmembrane protein 132D
chr1_-_155947951 0.63 ENST00000313695.7
ENST00000497907.1
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr13_-_52027134 0.62 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr15_+_75498739 0.61 ENST00000565074.1
chromosome 15 open reading frame 39
chr12_+_119419294 0.61 ENST00000267260.4
serine/arginine repetitive matrix 4
chr17_-_7082861 0.60 ENST00000269299.3
asialoglycoprotein receptor 1
chr8_+_38261880 0.60 ENST00000527175.1
leucine zipper-EF-hand containing transmembrane protein 2
chr8_+_144816303 0.59 ENST00000533004.1
FAM83H antisense RNA 1 (head to head)
chr19_-_8675559 0.59 ENST00000597188.1
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr17_+_38474489 0.59 ENST00000394089.2
ENST00000425707.3
retinoic acid receptor, alpha
chr19_-_51192661 0.58 ENST00000391813.1
SH3 and multiple ankyrin repeat domains 1
chr12_+_62654119 0.58 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
ubiquitin specific peptidase 15
chr12_+_6554021 0.58 ENST00000266557.3
CD27 molecule
chr8_-_66753682 0.58 ENST00000396642.3
phosphodiesterase 7A
chr2_-_163695128 0.58 ENST00000332142.5
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr8_-_145331153 0.57 ENST00000377412.4
KM-PA-2 protein; Uncharacterized protein
chr10_-_75415825 0.57 ENST00000394810.2
synaptopodin 2-like
chr12_+_26348582 0.57 ENST00000535504.1
sarcospan
chr17_+_58499066 0.56 ENST00000474834.1
chromosome 17 open reading frame 64
chr4_+_190992387 0.56 ENST00000554906.2
ENST00000553820.2
double homeobox 4 like 7
chr19_-_57352064 0.56 ENST00000326441.9
ENST00000593695.1
ENST00000599577.1
ENST00000594389.1
ENST00000423103.2
ENST00000598410.1
ENST00000593711.1
ENST00000391708.3
ENST00000221722.5
ENST00000599935.1
paternally expressed 3
zinc finger, imprinted 2
chr3_+_154797428 0.55 ENST00000460393.1
membrane metallo-endopeptidase
chr1_-_31712401 0.54 ENST00000373736.2
Na+/K+ transporting ATPase interacting 1
chr16_+_21169976 0.54 ENST00000572258.1
ENST00000261388.3
ENST00000451578.2
ENST00000572599.1
ENST00000577162.1
transmembrane protein 159
chr3_+_8775466 0.54 ENST00000343849.2
ENST00000397368.2
caveolin 3
chr4_-_6474173 0.54 ENST00000382599.4
protein phosphatase 2, regulatory subunit B, gamma
chr17_-_58499698 0.53 ENST00000590297.1
ubiquitin specific peptidase 32
chr11_+_128562372 0.52 ENST00000344954.6
Fli-1 proto-oncogene, ETS transcription factor
chr11_-_2323089 0.50 ENST00000456145.2
chromosome 11 open reading frame 21
chrX_-_151307020 0.50 ENST00000370323.4
ENST00000244096.3
ENST00000427322.2
melanoma antigen family A, 10
chr11_-_64703354 0.49 ENST00000532246.1
ENST00000279168.2
glycoprotein hormone alpha 2
chr2_+_127066059 0.49 ENST00000435352.1
AC023347.1
chr4_+_56719782 0.49 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
exocyst complex component 1
chr19_+_35609380 0.49 ENST00000604621.1
FXYD domain containing ion transport regulator 3
chr12_+_54447637 0.49 ENST00000609810.1
ENST00000430889.2
homeobox C4
Homeobox protein Hox-C4
chr5_+_151151471 0.49 ENST00000394123.3
ENST00000543466.1
GTPase activating protein (SH3 domain) binding protein 1
chr17_-_4167142 0.48 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ankyrin repeat and FYVE domain containing 1
chr11_-_85780086 0.48 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
phosphatidylinositol binding clathrin assembly protein
chr12_-_57940904 0.48 ENST00000550954.1
ENST00000434715.3
ENST00000546670.1
ENST00000543672.1
dynactin 2 (p50)
chr8_+_73449625 0.48 ENST00000523207.1
potassium voltage-gated channel, Shab-related subfamily, member 2
chr15_-_70390213 0.48 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr8_+_145064233 0.48 ENST00000529301.1
ENST00000395068.4
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr2_-_202508169 0.47 ENST00000409883.2
transmembrane protein 237
chr11_+_46403194 0.47 ENST00000395569.4
ENST00000395566.4
midkine (neurite growth-promoting factor 2)
chr12_-_57941004 0.46 ENST00000550750.1
ENST00000548249.1
dynactin 2 (p50)
chrX_-_153979315 0.46 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GRB2-associated binding protein 3
chr10_-_103603677 0.46 ENST00000358038.3
Kv channel interacting protein 2
chr16_+_68771128 0.46 ENST00000261769.5
ENST00000422392.2
cadherin 1, type 1, E-cadherin (epithelial)
chr11_+_46403303 0.45 ENST00000407067.1
ENST00000395565.1
midkine (neurite growth-promoting factor 2)
chr20_+_33462888 0.44 ENST00000336325.4
acyl-CoA synthetase short-chain family member 2
chr18_+_55102917 0.44 ENST00000491143.2
one cut homeobox 2
chr14_+_74353320 0.44 ENST00000540593.1
ENST00000555730.1
zinc finger protein 410
chr12_+_44152740 0.44 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
interleukin-1 receptor-associated kinase 4
chr1_-_28559502 0.43 ENST00000263697.4
DnaJ (Hsp40) homolog, subfamily C, member 8

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 19.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.3 3.9 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
1.1 3.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.8 17.1 GO:0016540 protein autoprocessing(GO:0016540)
0.6 1.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.6 1.7 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.5 3.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.4 1.3 GO:0050894 determination of affect(GO:0050894)
0.4 1.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 6.1 GO:0006183 GTP biosynthetic process(GO:0006183)
0.4 1.1 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.4 3.9 GO:0070141 response to UV-A(GO:0070141)
0.3 1.0 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.3 1.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 2.2 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.3 4.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 2.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 2.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 2.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 1.6 GO:0030421 defecation(GO:0030421)
0.3 0.8 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.2 0.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 6.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 2.7 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.2 1.5 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 1.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 0.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 2.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.2 1.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 0.9 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.2 0.7 GO:0071484 cellular response to light intensity(GO:0071484)
0.2 1.2 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 1.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 0.9 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 1.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.7 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.7 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.7 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1 2.1 GO:0043320 natural killer cell degranulation(GO:0043320)
0.1 0.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.6 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 1.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.4 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 0.5 GO:0033292 T-tubule organization(GO:0033292) positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.6 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 2.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 2.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.6 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 1.2 GO:0001675 acrosome assembly(GO:0001675)
0.1 1.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 7.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 2.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.8 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.7 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.1 1.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.2 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.5 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.1 1.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.8 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.3 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.2 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 1.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.4 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.3 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.8 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:1904847 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0007512 adult heart development(GO:0007512)
0.0 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.4 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.0 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.7 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 1.0 GO:0046039 GTP metabolic process(GO:0046039)
0.0 1.3 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 3.1 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.5 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.9 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 1.0 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 4.7 GO:0031424 keratinization(GO:0031424)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 2.0 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) cranial suture morphogenesis(GO:0060363) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 1.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.9 GO:0030317 sperm motility(GO:0030317)
0.0 0.5 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 19.1 GO:0097209 epidermal lamellar body(GO:0097209)
1.0 7.8 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.6 2.6 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.6 3.2 GO:0070876 SOSS complex(GO:0070876)
0.6 1.7 GO:0055028 cortical microtubule(GO:0055028)
0.2 0.7 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.2 1.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 2.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.2 GO:0051286 cell tip(GO:0051286)
0.1 1.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 3.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 2.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 0.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 6.3 GO:0045178 basal part of cell(GO:0045178)
0.1 1.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 2.6 GO:0030673 axolemma(GO:0030673)
0.1 0.9 GO:0005869 dynactin complex(GO:0005869)
0.1 1.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 8.8 GO:0005882 intermediate filament(GO:0005882)
0.1 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.0 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 1.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 3.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 4.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 1.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 15.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 1.6 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.6 3.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.5 4.7 GO:1901612 cardiolipin binding(GO:1901612)
0.5 1.5 GO:0032090 Pyrin domain binding(GO:0032090)
0.4 1.3 GO:0031877 somatostatin receptor binding(GO:0031877)
0.4 6.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.4 2.7 GO:1990254 keratin filament binding(GO:1990254)
0.4 1.5 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.4 1.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 1.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 3.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 0.9 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.3 1.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.3 4.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 0.7 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.7 GO:0070984 SET domain binding(GO:0070984)
0.2 0.7 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 1.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 0.8 GO:0016936 galactoside binding(GO:0016936)
0.2 1.0 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.5 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 1.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.9 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.1 GO:0004672 protein kinase activity(GO:0004672)
0.1 2.6 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.2 GO:0030911 TPR domain binding(GO:0030911)
0.1 33.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 4.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.5 GO:0016866 intramolecular transferase activity(GO:0016866)
0.1 0.7 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 2.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.4 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1 1.2 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.9 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 2.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.9 GO:0017166 vinculin binding(GO:0017166)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 1.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 1.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0044325 ion channel binding(GO:0044325)
0.0 1.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 5.4 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 17.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 7.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 4.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 5.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.7 PID AURORA B PATHWAY Aurora B signaling
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.5 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 2.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 4.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease