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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SOX1

Z-value: 0.63

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Transcription factors associated with SOX1

Gene Symbol Gene ID Gene Info
SOX1
ENSG00000182968.3 SRY-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX1hg19_v2_chr13_+_112721913_1127219130.451.3e-02Click!

Activity profile of SOX1 motif

Sorted Z-values of SOX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_152957707 2.25 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr1_+_152975488 2.19 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr11_+_125496619 1.98 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr13_+_109248500 1.92 ENST00000356711.2
MYO16
myosin XVI
chr16_+_12059050 1.62 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr7_+_142457315 1.58 ENST00000486171.1
ENST00000311737.7
PRSS1
protease, serine, 1 (trypsin 1)
chr16_+_12058961 1.55 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr9_-_123638633 1.49 ENST00000456291.1
PHF19
PHD finger protein 19
chr11_+_125496400 1.48 ENST00000524737.1
CHEK1
checkpoint kinase 1
chr11_+_125496124 1.34 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr2_+_11864458 1.16 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1
lipin 1
chr3_-_189840223 0.97 ENST00000427335.2
LEPREL1
leprecan-like 1
chrX_+_2976652 0.85 ENST00000537104.1
ARSF
arylsulfatase F
chr13_+_49280951 0.85 ENST00000282018.3
CYSLTR2
cysteinyl leukotriene receptor 2
chr1_-_89641680 0.83 ENST00000294671.2
GBP7
guanylate binding protein 7
chr4_+_156680153 0.83 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr12_+_75874460 0.82 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr20_-_48747662 0.81 ENST00000371656.2
TMEM189
transmembrane protein 189
chr2_+_87808725 0.73 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr3_+_136676851 0.72 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr1_-_52499443 0.69 ENST00000371614.1
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr11_-_76381029 0.68 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr3_+_136676707 0.67 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr11_-_76381781 0.66 ENST00000260061.5
ENST00000404995.1
LRRC32
leucine rich repeat containing 32
chr16_+_12059091 0.66 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_+_70876926 0.63 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr2_+_102615416 0.62 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr12_+_93096619 0.59 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr10_-_75401500 0.56 ENST00000359322.4
MYOZ1
myozenin 1
chr20_-_23586513 0.56 ENST00000376971.3
CST9
cystatin 9 (testatin)
chr3_-_16524357 0.56 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr3_-_33686925 0.55 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr2_-_209054709 0.55 ENST00000449053.1
ENST00000451346.1
ENST00000341287.4
C2orf80
chromosome 2 open reading frame 80
chr18_+_21719018 0.54 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr5_-_16916624 0.52 ENST00000513882.1
MYO10
myosin X
chr1_-_43638168 0.52 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr1_+_65613340 0.50 ENST00000546702.1
AK4
adenylate kinase 4
chr10_-_73976884 0.48 ENST00000317126.4
ENST00000545550.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr1_-_237167718 0.46 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr19_-_44388116 0.44 ENST00000587539.1
ZNF404
zinc finger protein 404
chr15_+_76196234 0.42 ENST00000540507.1
ENST00000565036.1
ENST00000569054.1
FBXO22
F-box protein 22
chr2_+_171034646 0.42 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr1_+_184020811 0.42 ENST00000361641.1
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr14_+_22508822 0.41 ENST00000390448.3
TRAV20
T cell receptor alpha variable 20
chr1_+_184020830 0.40 ENST00000533373.1
ENST00000423085.2
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr6_+_26183958 0.38 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr6_+_28249299 0.38 ENST00000405948.2
PGBD1
piggyBac transposable element derived 1
chr11_-_113577014 0.38 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5
chr11_+_62009653 0.36 ENST00000244926.3
SCGB1D2
secretoglobin, family 1D, member 2
chr9_-_85882145 0.35 ENST00000328788.1
FRMD3
FERM domain containing 3
chr11_-_78052923 0.34 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr9_-_104249400 0.34 ENST00000374848.3
TMEM246
transmembrane protein 246
chr12_+_115800817 0.34 ENST00000547948.1
RP11-116D17.1
HCG2038717; Uncharacterized protein
chr10_-_73976025 0.33 ENST00000342444.4
ENST00000533958.1
ENST00000527593.1
ENST00000394915.3
ENST00000530461.1
ENST00000317168.6
ENST00000524829.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr20_-_49575058 0.32 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr20_-_49575081 0.32 ENST00000371588.5
ENST00000371582.4
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr5_-_95158644 0.30 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr11_-_113577052 0.30 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5
transmembrane protease, serine 5
chr6_+_28249332 0.30 ENST00000259883.3
PGBD1
piggyBac transposable element derived 1
chr12_+_100594557 0.29 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr2_+_171036635 0.28 ENST00000484338.2
ENST00000334231.6
MYO3B
myosin IIIB
chr2_-_14541060 0.28 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr18_-_51751132 0.27 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr1_-_19578003 0.27 ENST00000375199.3
ENST00000375208.3
ENST00000356068.2
ENST00000477853.1
EMC1
ER membrane protein complex subunit 1
chr12_+_9980069 0.26 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr8_+_145133493 0.26 ENST00000316052.5
ENST00000525936.1
EXOSC4
exosome component 4
chr6_+_149539767 0.25 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2
RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr1_+_65613217 0.24 ENST00000545314.1
AK4
adenylate kinase 4
chr12_-_7848364 0.24 ENST00000329913.3
GDF3
growth differentiation factor 3
chr9_-_95244781 0.24 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr20_-_14318248 0.23 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr14_-_25078864 0.23 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
GZMH
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr12_-_127174806 0.23 ENST00000545853.1
ENST00000537478.1
RP11-407A16.3
RP11-407A16.3
chr17_+_19186292 0.22 ENST00000395626.1
ENST00000571254.1
EPN2
epsin 2
chr7_-_36634181 0.22 ENST00000538464.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr19_+_55385682 0.21 ENST00000391726.3
FCAR
Fc fragment of IgA, receptor for
chr9_-_95166841 0.21 ENST00000262551.4
OGN
osteoglycin
chr10_+_15085895 0.21 ENST00000378228.3
OLAH
oleoyl-ACP hydrolase
chrX_+_106163626 0.20 ENST00000336803.1
CLDN2
claudin 2
chr3_+_127770455 0.20 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr9_-_95166884 0.20 ENST00000375561.5
OGN
osteoglycin
chr5_-_150460914 0.20 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr11_-_18062872 0.19 ENST00000250018.2
TPH1
tryptophan hydroxylase 1
chr14_-_20801427 0.18 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr14_+_22356029 0.18 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr17_+_34391625 0.18 ENST00000004921.3
CCL18
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
chr6_+_123317116 0.18 ENST00000275162.5
CLVS2
clavesin 2
chr4_+_26585538 0.17 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr17_-_39646116 0.17 ENST00000328119.6
KRT36
keratin 36
chr11_-_104827425 0.16 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr16_-_11876408 0.16 ENST00000396516.2
ZC3H7A
zinc finger CCCH-type containing 7A
chr12_-_10607084 0.16 ENST00000408006.3
ENST00000544822.1
ENST00000536188.1
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr4_-_122686261 0.15 ENST00000337677.5
TMEM155
transmembrane protein 155
chr12_-_10605929 0.15 ENST00000347831.5
ENST00000359151.3
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr1_-_200379129 0.14 ENST00000367353.1
ZNF281
zinc finger protein 281
chr19_+_21324863 0.13 ENST00000598331.1
ZNF431
zinc finger protein 431
chr14_-_74417096 0.13 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chr6_-_71666732 0.13 ENST00000230053.6
B3GAT2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr19_+_3762703 0.12 ENST00000589174.1
MRPL54
mitochondrial ribosomal protein L54
chr10_+_78078088 0.12 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr11_-_57177586 0.12 ENST00000529411.1
RP11-872D17.8
Uncharacterized protein
chr14_+_21249200 0.11 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr1_+_206516200 0.09 ENST00000295713.5
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr19_-_50990785 0.09 ENST00000595005.1
CTD-2545M3.8
CTD-2545M3.8
chr3_-_58200398 0.09 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
DNASE1L3
deoxyribonuclease I-like 3
chr3_-_126327398 0.08 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr4_-_170924888 0.07 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr10_+_23384435 0.07 ENST00000376510.3
MSRB2
methionine sulfoxide reductase B2
chrX_+_129040122 0.06 ENST00000394422.3
ENST00000371051.5
UTP14A
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr1_-_200379180 0.06 ENST00000294740.3
ZNF281
zinc finger protein 281
chr8_-_102181718 0.05 ENST00000565617.1
KB-1460A1.5
KB-1460A1.5
chrX_+_129040094 0.05 ENST00000425117.2
UTP14A
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr12_+_9980113 0.05 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr3_-_58613323 0.05 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr11_-_133715394 0.03 ENST00000299140.3
ENST00000532889.1
SPATA19
spermatogenesis associated 19
chr1_-_200379104 0.03 ENST00000367352.3
ZNF281
zinc finger protein 281
chr20_+_54823788 0.03 ENST00000243911.2
MC3R
melanocortin 3 receptor
chr12_-_110434096 0.03 ENST00000320063.9
ENST00000457474.2
ENST00000547815.1
ENST00000361006.5
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr3_+_178276488 0.03 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr4_-_74486217 0.03 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr15_+_59903975 0.02 ENST00000560585.1
ENST00000396065.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr7_-_142176790 0.02 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr1_+_144811943 0.02 ENST00000281815.8
NBPF9
neuroblastoma breakpoint family, member 9
chr3_-_185655795 0.01 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
TRA2B
transformer 2 beta homolog (Drosophila)
chr1_+_148560843 0.01 ENST00000442702.2
ENST00000369187.3
NBPF15
neuroblastoma breakpoint family, member 15
chr1_-_112106556 0.01 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr10_-_96829246 0.01 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr17_-_15168624 0.00 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr8_-_93029520 0.00 ENST00000521553.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.8 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 1.4 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.2 1.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 0.6 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 0.6 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 1.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.8 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 1.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.1 4.4 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.2 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 3.8 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.4 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.9 GO:0021549 cerebellum development(GO:0021549)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.4 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 4.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 5.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 3.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 2.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.7 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.8 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.8 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.6 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 0.2 GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.4 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.0 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening