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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SOX10_SOX15

Z-value: 0.37

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Transcription factors associated with SOX10_SOX15

Gene Symbol Gene ID Gene Info
SOX10
ENSG00000100146.12 SRY-box transcription factor 10
SOX15
ENSG00000129194.3 SRY-box transcription factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX10hg19_v2_chr22_-_38380543_383805690.144.8e-01Click!
SOX15hg19_v2_chr17_-_7493390_7493488-0.019.7e-01Click!

Activity profile of SOX10_SOX15 motif

Sorted Z-values of SOX10_SOX15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_86564776 0.62 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr2_-_118943930 0.54 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr3_-_123339418 0.42 ENST00000583087.1
MYLK
myosin light chain kinase
chr15_+_84115868 0.42 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr3_-_123339343 0.42 ENST00000578202.1
MYLK
myosin light chain kinase
chr6_-_127840336 0.39 ENST00000525778.1
SOGA3
SOGA family member 3
chr2_+_10262857 0.39 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr4_+_154387480 0.36 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr11_+_125496619 0.33 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr1_-_200992827 0.31 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr6_-_127840021 0.29 ENST00000465909.2
SOGA3
SOGA family member 3
chrY_+_15016013 0.27 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr7_-_99869799 0.27 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr3_+_39509163 0.27 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr3_-_141747950 0.26 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr5_-_157002775 0.25 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr6_-_139613269 0.25 ENST00000358430.3
TXLNB
taxilin beta
chr3_+_111260856 0.25 ENST00000352690.4
CD96
CD96 molecule
chr19_-_51472823 0.25 ENST00000310157.2
KLK6
kallikrein-related peptidase 6
chr7_-_121944491 0.24 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr1_+_47799542 0.23 ENST00000471289.2
ENST00000450808.2
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr6_-_28411241 0.22 ENST00000289788.4
ZSCAN23
zinc finger and SCAN domain containing 23
chrX_-_45629661 0.21 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
RP6-99M1.2
chr17_+_75447326 0.21 ENST00000591088.1
SEPT9
septin 9
chr14_-_57272366 0.20 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr12_-_42631529 0.20 ENST00000548917.1
YAF2
YY1 associated factor 2
chr22_-_23484246 0.20 ENST00000216036.4
RTDR1
rhabdoid tumor deletion region gene 1
chr3_+_39509070 0.19 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr18_-_74728998 0.19 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr11_-_94965667 0.19 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr2_-_166060552 0.19 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr2_+_162272605 0.18 ENST00000389554.3
TBR1
T-box, brain, 1
chr3_+_141105235 0.18 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr12_+_104359641 0.18 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr2_-_166060571 0.18 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr6_-_42419649 0.18 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr2_+_27237615 0.17 ENST00000458529.1
ENST00000402218.1
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr17_+_7590734 0.17 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr5_+_137514834 0.16 ENST00000508792.1
ENST00000504621.1
KIF20A
kinesin family member 20A
chr5_+_137514687 0.16 ENST00000394894.3
KIF20A
kinesin family member 20A
chr11_+_86106208 0.16 ENST00000528728.1
CCDC81
coiled-coil domain containing 81
chr14_+_97263641 0.16 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr2_-_47572105 0.16 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
AC073283.4
chr15_+_63335899 0.15 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr1_-_53793584 0.15 ENST00000354412.3
ENST00000347547.2
ENST00000306052.6
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr17_-_9940058 0.15 ENST00000585266.1
GAS7
growth arrest-specific 7
chrX_+_150869023 0.15 ENST00000448324.1
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr2_-_10588630 0.15 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr2_-_1748214 0.15 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN
peroxidasin homolog (Drosophila)
chr8_+_81398444 0.14 ENST00000455036.3
ENST00000426744.2
ZBTB10
zinc finger and BTB domain containing 10
chr12_-_8815299 0.14 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr12_-_49582593 0.14 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr3_+_151986709 0.14 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr12_-_8815215 0.14 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr6_+_30689350 0.14 ENST00000330914.3
TUBB
tubulin, beta class I
chr4_-_123377880 0.14 ENST00000226730.4
IL2
interleukin 2
chr6_+_72596604 0.14 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr6_-_27880174 0.14 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr7_-_111846435 0.13 ENST00000437633.1
ENST00000428084.1
DOCK4
dedicator of cytokinesis 4
chr11_-_66445219 0.13 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chr17_-_56406117 0.13 ENST00000268893.6
ENST00000355701.3
BZRAP1
benzodiazepine receptor (peripheral) associated protein 1
chrX_+_129473859 0.13 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr22_+_39052632 0.13 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr15_+_84116106 0.13 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr1_-_79472365 0.13 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr15_-_88799948 0.13 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr11_+_128563652 0.13 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr5_-_157002749 0.12 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19
ADAM metallopeptidase domain 19
chr13_+_30002741 0.12 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr11_-_10829851 0.12 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chrX_-_117107542 0.12 ENST00000371878.1
KLHL13
kelch-like family member 13
chr5_-_138718973 0.12 ENST00000353963.3
ENST00000348729.3
SLC23A1
solute carrier family 23 (ascorbic acid transporter), member 1
chr6_-_112575838 0.12 ENST00000455073.1
LAMA4
laminin, alpha 4
chr2_-_188312971 0.12 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr3_-_167813132 0.12 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr1_+_174417095 0.12 ENST00000367685.2
GPR52
G protein-coupled receptor 52
chr17_-_7297519 0.11 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr1_+_215256467 0.11 ENST00000391894.2
ENST00000444842.2
KCNK2
potassium channel, subfamily K, member 2
chr7_-_148581251 0.11 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr5_-_65017921 0.11 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr19_+_47105309 0.11 ENST00000599839.1
ENST00000596362.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr13_-_24007815 0.11 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr18_+_6729698 0.11 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr7_+_107110488 0.11 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr1_-_26233423 0.11 ENST00000357865.2
STMN1
stathmin 1
chr1_+_240255166 0.11 ENST00000319653.9
FMN2
formin 2
chr10_-_97321165 0.11 ENST00000306402.6
SORBS1
sorbin and SH3 domain containing 1
chr5_+_60933634 0.11 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr3_-_71353892 0.10 ENST00000484350.1
FOXP1
forkhead box P1
chr6_-_161695042 0.10 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr16_+_89989687 0.10 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
TUBB3
Tubulin beta-3 chain
chr4_-_138453606 0.10 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr9_-_120177342 0.10 ENST00000361209.2
ASTN2
astrotactin 2
chr14_-_51027838 0.10 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr6_-_161695074 0.10 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr17_-_7297833 0.10 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chrX_+_36254051 0.10 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr6_-_134861089 0.10 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr11_+_111808119 0.10 ENST00000531396.1
DIXDC1
DIX domain containing 1
chr11_-_5364809 0.10 ENST00000300773.2
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr12_-_11508520 0.09 ENST00000545626.1
ENST00000500254.2
PRB1
proline-rich protein BstNI subfamily 1
chr8_+_67039131 0.09 ENST00000315962.4
ENST00000353317.5
TRIM55
tripartite motif containing 55
chr11_+_111807863 0.09 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr8_-_9760839 0.09 ENST00000519461.1
ENST00000517675.1
LINC00599
long intergenic non-protein coding RNA 599
chr7_+_154002189 0.09 ENST00000332007.3
DPP6
dipeptidyl-peptidase 6
chr20_+_44036620 0.09 ENST00000372710.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr6_-_30654977 0.09 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr8_+_67039278 0.09 ENST00000276573.7
ENST00000350034.4
TRIM55
tripartite motif containing 55
chr20_-_4804244 0.09 ENST00000379400.3
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr11_-_89224488 0.09 ENST00000534731.1
ENST00000527626.1
NOX4
NADPH oxidase 4
chr17_-_49124230 0.09 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr7_-_94953878 0.09 ENST00000222381.3
PON1
paraoxonase 1
chr1_-_6479963 0.09 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
HES2
hes family bHLH transcription factor 2
chr11_-_89224299 0.09 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NOX4
NADPH oxidase 4
chr17_+_36584662 0.09 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr12_-_11548496 0.09 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr17_-_18950310 0.09 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr3_-_167813672 0.09 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr16_+_84801852 0.09 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr2_-_26205340 0.09 ENST00000264712.3
KIF3C
kinesin family member 3C
chr7_+_134551583 0.08 ENST00000435928.1
CALD1
caldesmon 1
chr16_+_27078219 0.08 ENST00000418886.1
C16orf82
chromosome 16 open reading frame 82
chr1_+_24117627 0.08 ENST00000400061.1
LYPLA2
lysophospholipase II
chr1_+_197886461 0.08 ENST00000367388.3
ENST00000337020.2
ENST00000367387.4
LHX9
LIM homeobox 9
chr10_+_24528108 0.08 ENST00000438429.1
KIAA1217
KIAA1217
chr12_-_11463353 0.08 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
PRB4
proline-rich protein BstNI subfamily 4
chr15_-_50647370 0.08 ENST00000558970.1
ENST00000396464.3
ENST00000560825.1
GABPB1
GA binding protein transcription factor, beta subunit 1
chr19_+_34287174 0.08 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr17_-_79849438 0.08 ENST00000331204.4
ENST00000505490.2
ALYREF
Aly/REF export factor
chr17_+_67498538 0.08 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr14_-_71107921 0.08 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr2_-_153573965 0.08 ENST00000448428.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr15_-_70388943 0.08 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr2_+_153191706 0.08 ENST00000288670.9
FMNL2
formin-like 2
chr11_+_67007518 0.08 ENST00000530342.1
ENST00000308783.5
KDM2A
lysine (K)-specific demethylase 2A
chr8_-_87755878 0.07 ENST00000320005.5
CNGB3
cyclic nucleotide gated channel beta 3
chr6_+_30689401 0.07 ENST00000396389.1
ENST00000396384.1
TUBB
tubulin, beta class I
chr11_-_89224508 0.07 ENST00000525196.1
NOX4
NADPH oxidase 4
chr1_+_11751748 0.07 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein
chr20_+_20348740 0.07 ENST00000310227.1
INSM1
insulinoma-associated 1
chr7_-_150924121 0.07 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
ABCF2
ATP-binding cassette, sub-family F (GCN20), member 2
chr12_+_15475462 0.07 ENST00000543886.1
ENST00000348962.2
PTPRO
protein tyrosine phosphatase, receptor type, O
chr6_-_165989936 0.07 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr15_+_92937058 0.07 ENST00000268164.3
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr14_-_50583271 0.07 ENST00000395860.2
ENST00000395859.2
VCPKMT
valosin containing protein lysine (K) methyltransferase
chr17_+_75283973 0.07 ENST00000431235.2
ENST00000449803.2
SEPT9
septin 9
chr3_+_111260954 0.07 ENST00000283285.5
CD96
CD96 molecule
chr5_-_150521192 0.07 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chr15_-_50647347 0.07 ENST00000220429.8
ENST00000429662.2
GABPB1
GA binding protein transcription factor, beta subunit 1
chr4_+_95128748 0.07 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_9005917 0.07 ENST00000549778.1
ENST00000480186.3
ENST00000377443.2
ENST00000377436.3
ENST00000377442.2
CA6
carbonic anhydrase VI
chr12_-_95611149 0.07 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr22_-_21984282 0.07 ENST00000398873.3
ENST00000292778.6
YDJC
YdjC homolog (bacterial)
chr12_+_26111823 0.07 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr15_-_88799384 0.07 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chrX_-_46187069 0.07 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr12_+_31477250 0.07 ENST00000313737.4
AC024940.1
AC024940.1
chr8_+_81397846 0.07 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr4_+_95129061 0.07 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr20_+_60698180 0.06 ENST00000361670.3
LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chrX_-_13956497 0.06 ENST00000398361.3
GPM6B
glycoprotein M6B
chr17_-_48072574 0.06 ENST00000434704.2
DLX3
distal-less homeobox 3
chr13_+_111767650 0.06 ENST00000449979.1
ENST00000370623.3
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chrX_-_24665353 0.06 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr19_+_10765699 0.06 ENST00000590009.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr4_-_5890145 0.06 ENST00000397890.2
CRMP1
collapsin response mediator protein 1
chr7_+_23145884 0.06 ENST00000409689.1
ENST00000410047.1
KLHL7
kelch-like family member 7
chr15_-_50647274 0.06 ENST00000543881.1
GABPB1
GA binding protein transcription factor, beta subunit 1
chr3_-_4927447 0.06 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr15_+_58724184 0.06 ENST00000433326.2
LIPC
lipase, hepatic
chr6_-_91006461 0.06 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr20_-_22559211 0.06 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr2_-_161350305 0.06 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_-_209028300 0.06 ENST00000304502.4
CRYGA
crystallin, gamma A
chr7_-_27219849 0.05 ENST00000396344.4
HOXA10
homeobox A10
chr17_+_64961026 0.05 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr15_-_88799661 0.05 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr6_-_112575912 0.05 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr12_-_90049878 0.05 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr4_-_80994210 0.05 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr12_-_90049828 0.05 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr4_+_95128996 0.05 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_-_119031228 0.05 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr13_+_98795505 0.05 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr13_+_78315466 0.05 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr13_+_98795434 0.05 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr7_-_27142290 0.05 ENST00000222718.5
HOXA2
homeobox A2
chr15_-_56035177 0.05 ENST00000389286.4
ENST00000561292.1
PRTG
protogenin
chr18_+_32558208 0.05 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr7_+_69064566 0.05 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr17_-_46690839 0.05 ENST00000498634.2
HOXB8
homeobox B8
chr6_+_114178512 0.05 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr21_+_30671690 0.05 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrX_-_142722897 0.05 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr5_+_38148582 0.05 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr12_+_113495492 0.05 ENST00000257600.3
DTX1
deltex homolog 1 (Drosophila)
chr20_-_30795511 0.05 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr8_+_81397876 0.05 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr2_+_32288657 0.05 ENST00000345662.1
SPAST
spastin
chrX_-_63425561 0.05 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX10_SOX15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.2 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.2 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.2 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.0 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:0072376 blood coagulation, intrinsic pathway(GO:0007597) protein activation cascade(GO:0072376) blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.0 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.0 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC