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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SOX17

Z-value: 0.89

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Transcription factors associated with SOX17

Gene Symbol Gene ID Gene Info
SOX17
ENSG00000164736.5 SRY-box transcription factor 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX17hg19_v2_chr8_+_55370487_55370503-0.613.5e-04Click!

Activity profile of SOX17 motif

Sorted Z-values of SOX17 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_71533055 9.64 ENST00000552128.1
TSPAN8
tetraspanin 8
chrY_+_2709906 4.19 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr8_+_72587535 4.00 ENST00000519840.1
ENST00000521131.1
RP11-1144P22.1
RP11-1144P22.1
chr13_-_39564993 3.73 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr6_-_32920794 3.54 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr3_-_19975665 3.38 ENST00000295824.9
ENST00000389256.4
EFHB
EF-hand domain family, member B
chr17_+_41158742 2.55 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr14_-_93673353 2.49 ENST00000556566.1
ENST00000306954.4
C14orf142
chromosome 14 open reading frame 142
chrX_-_38186811 2.42 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr6_-_52668605 2.27 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr3_-_167371740 2.10 ENST00000466760.1
ENST00000479765.1
WDR49
WD repeat domain 49
chr5_-_16509101 2.08 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr17_+_68100989 2.08 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_-_52710893 2.04 ENST00000284562.2
GSTA5
glutathione S-transferase alpha 5
chr8_+_110098850 2.03 ENST00000518632.1
TRHR
thyrotropin-releasing hormone receptor
chr2_+_233527443 1.82 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr19_-_10764509 1.71 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr10_-_69597915 1.62 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr12_-_15374343 1.61 ENST00000256953.2
ENST00000546331.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chr5_+_68860949 1.54 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr4_-_100212132 1.50 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr5_-_41213607 1.47 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr11_-_108464465 1.45 ENST00000525344.1
EXPH5
exophilin 5
chr3_-_52488048 1.44 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chrX_-_55187531 1.38 ENST00000489298.1
ENST00000477847.2
FAM104B
family with sequence similarity 104, member B
chr16_+_71560023 1.36 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr4_-_76008706 1.36 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5
RP11-44F21.5
chr6_+_159071015 1.33 ENST00000360448.3
SYTL3
synaptotagmin-like 3
chr13_+_24144796 1.33 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr14_+_22694606 1.31 ENST00000390463.3
TRAV36DV7
T cell receptor alpha variable 36/delta variable 7
chr3_+_125687987 1.30 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B
rhophilin associated tail protein 1B
chr11_+_17316870 1.28 ENST00000458064.2
NUCB2
nucleobindin 2
chr9_+_86237963 1.27 ENST00000277124.8
IDNK
idnK, gluconokinase homolog (E. coli)
chr1_+_15256230 1.26 ENST00000376028.4
ENST00000400798.2
KAZN
kazrin, periplakin interacting protein
chr1_+_171217622 1.24 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chrX_-_55187588 1.24 ENST00000472571.2
ENST00000332132.4
ENST00000425133.2
ENST00000358460.4
FAM104B
family with sequence similarity 104, member B
chr2_-_38303218 1.23 ENST00000407341.1
ENST00000260630.3
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr8_+_110099653 1.21 ENST00000311762.2
TRHR
thyrotropin-releasing hormone receptor
chr1_+_171283331 1.20 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr6_-_52628271 1.20 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr5_-_159827073 1.18 ENST00000408953.3
C5orf54
chromosome 5 open reading frame 54
chr2_-_27851843 1.17 ENST00000324364.3
CCDC121
coiled-coil domain containing 121
chr2_-_157198860 1.17 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr19_-_9006766 1.17 ENST00000599436.1
MUC16
mucin 16, cell surface associated
chr1_-_48937838 1.16 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr12_+_55248289 1.15 ENST00000308796.6
MUCL1
mucin-like 1
chr18_-_19748331 1.14 ENST00000584201.1
GATA6-AS1
GATA6 antisense RNA 1 (head to head)
chr19_-_9003586 1.13 ENST00000380951.5
MUC16
mucin 16, cell surface associated
chr19_+_58514229 1.13 ENST00000546949.1
ENST00000553254.1
ENST00000547364.1
CTD-2368P22.1
HCG1811579; Uncharacterized protein
chr15_+_88120158 1.11 ENST00000560153.1
LINC00052
long intergenic non-protein coding RNA 52
chr5_-_159827033 1.09 ENST00000523213.1
C5orf54
chromosome 5 open reading frame 54
chr1_+_227751231 1.09 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
ZNF678
zinc finger protein 678
chr1_+_174844645 1.08 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr12_-_111358372 1.08 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr2_-_159237472 1.07 ENST00000409187.1
CCDC148
coiled-coil domain containing 148
chr5_-_38595498 1.04 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr6_-_52705641 1.02 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr1_+_226013047 1.02 ENST00000366837.4
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr1_+_43312258 1.01 ENST00000372508.3
ENST00000372507.1
ENST00000372506.1
ENST00000397044.3
ENST00000372504.1
ZNF691
zinc finger protein 691
chr4_-_168155730 0.99 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr17_-_56621665 0.95 ENST00000321691.3
C17orf47
chromosome 17 open reading frame 47
chr1_-_48937821 0.91 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr12_-_40499661 0.90 ENST00000280871.4
SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13
chr6_+_26217159 0.88 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr20_-_45318230 0.87 ENST00000372114.3
TP53RK
TP53 regulating kinase
chr16_-_71523179 0.83 ENST00000564230.1
ENST00000565637.1
ZNF19
zinc finger protein 19
chr6_-_31745085 0.82 ENST00000375686.3
ENST00000447450.1
VWA7
von Willebrand factor A domain containing 7
chr6_-_31239846 0.82 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
HLA-C
major histocompatibility complex, class I, C
chr12_+_69742121 0.82 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr6_-_31745037 0.82 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr11_-_3818688 0.81 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
NUP98
nucleoporin 98kDa
chr14_-_70883708 0.81 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr10_+_53806501 0.81 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr16_+_29467780 0.81 ENST00000395400.3
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr11_-_110561721 0.80 ENST00000357139.3
ARHGAP20
Rho GTPase activating protein 20
chr12_+_104680659 0.76 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr3_-_49170522 0.76 ENST00000418109.1
LAMB2
laminin, beta 2 (laminin S)
chr2_-_118943930 0.75 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr17_+_76494911 0.75 ENST00000598378.1
DNAH17-AS1
DNAH17 antisense RNA 1
chr16_-_30023615 0.74 ENST00000564979.1
ENST00000563378.1
DOC2A
double C2-like domains, alpha
chr6_-_119256311 0.74 ENST00000316316.6
MCM9
minichromosome maintenance complex component 9
chr1_+_174417095 0.73 ENST00000367685.2
GPR52
G protein-coupled receptor 52
chr3_-_3152031 0.72 ENST00000383846.1
ENST00000427088.1
ENST00000446632.2
ENST00000438560.1
IL5RA
interleukin 5 receptor, alpha
chr19_-_19843900 0.71 ENST00000344099.3
ZNF14
zinc finger protein 14
chr3_-_49170405 0.70 ENST00000305544.4
ENST00000494831.1
LAMB2
laminin, beta 2 (laminin S)
chr16_-_71523236 0.70 ENST00000288177.5
ENST00000569072.1
ZNF19
zinc finger protein 19
chr15_-_81202118 0.69 ENST00000560560.1
RP11-351M8.1
Uncharacterized protein
chr19_-_19887185 0.68 ENST00000590092.1
ENST00000589910.1
ENST00000589508.1
ENST00000586645.1
ENST00000586816.1
ENST00000588223.1
ENST00000586885.1
LINC00663
long intergenic non-protein coding RNA 663
chr17_-_56605341 0.67 ENST00000583114.1
SEPT4
septin 4
chr15_+_34310428 0.65 ENST00000557872.1
CHRM5
cholinergic receptor, muscarinic 5
chr4_-_87028478 0.65 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chrX_+_129473916 0.64 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr12_-_57443886 0.64 ENST00000300119.3
MYO1A
myosin IA
chr16_+_16484691 0.64 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr19_+_6135646 0.64 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr2_-_100939195 0.62 ENST00000393437.3
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr6_+_32605134 0.62 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr10_-_27389392 0.61 ENST00000376087.4
ANKRD26
ankyrin repeat domain 26
chr17_-_58042075 0.61 ENST00000305783.8
ENST00000589113.1
ENST00000442346.2
RNFT1
ring finger protein, transmembrane 1
chr19_+_49956426 0.60 ENST00000293350.4
ENST00000540132.1
ENST00000455361.2
ENST00000433981.2
ALDH16A1
aldehyde dehydrogenase 16 family, member A1
chr7_+_139026057 0.60 ENST00000541515.3
LUC7L2
LUC7-like 2 (S. cerevisiae)
chr1_+_59775752 0.59 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr16_-_15474904 0.59 ENST00000534094.1
NPIPA5
nuclear pore complex interacting protein family, member A5
chr8_-_95220775 0.59 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr6_+_29910301 0.58 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr3_+_46412345 0.58 ENST00000292303.4
CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chrX_+_49216659 0.58 ENST00000415752.1
GAGE12I
G antigen 12I
chr3_-_123710893 0.58 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
ROPN1
rhophilin associated tail protein 1
chr6_+_28109703 0.56 ENST00000457389.2
ENST00000330236.6
ZKSCAN8
zinc finger with KRAB and SCAN domains 8
chr15_-_20193370 0.56 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr4_-_168155577 0.56 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr13_-_24895566 0.55 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr2_+_232573222 0.55 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr3_-_151176497 0.55 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr3_-_11610255 0.55 ENST00000424529.2
VGLL4
vestigial like 4 (Drosophila)
chr5_+_49962772 0.55 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr12_+_25205568 0.54 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr2_+_86668464 0.54 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr17_-_67264947 0.54 ENST00000586811.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr21_+_29911640 0.53 ENST00000412526.1
ENST00000455939.1
LINC00161
long intergenic non-protein coding RNA 161
chr6_-_26659913 0.53 ENST00000480036.1
ENST00000415922.2
ZNF322
zinc finger protein 322
chr4_-_150736962 0.52 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
RP11-526A4.1
chr20_-_43883197 0.52 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr1_+_40840320 0.52 ENST00000372708.1
SMAP2
small ArfGAP2
chr20_-_44168046 0.52 ENST00000372665.3
ENST00000372670.3
ENST00000600168.1
WFDC6
WAP four-disulfide core domain 6
chr19_-_48752812 0.52 ENST00000359009.4
CARD8
caspase recruitment domain family, member 8
chr4_-_168155700 0.51 ENST00000357545.4
ENST00000512648.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_+_205225319 0.50 ENST00000329800.7
TMCC2
transmembrane and coiled-coil domain family 2
chr10_-_115614127 0.50 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr19_-_44809121 0.49 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235
zinc finger protein 235
chr8_+_133931648 0.49 ENST00000519178.1
ENST00000542445.1
TG
thyroglobulin
chr1_-_160492994 0.49 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr11_-_123756334 0.48 ENST00000528595.1
ENST00000375026.2
TMEM225
transmembrane protein 225
chr6_-_152958521 0.48 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr13_+_103459704 0.48 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr9_-_115818951 0.47 ENST00000553380.1
ENST00000374227.3
ZFP37
ZFP37 zinc finger protein
chr19_-_48753104 0.47 ENST00000447740.2
CARD8
caspase recruitment domain family, member 8
chr6_-_42690312 0.47 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chr11_+_65266507 0.47 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr5_+_125758813 0.46 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr2_-_219906220 0.46 ENST00000458526.1
ENST00000409865.3
ENST00000410037.1
ENST00000457968.1
ENST00000436631.1
ENST00000341552.5
ENST00000441968.1
ENST00000295729.2
CCDC108
coiled-coil domain containing 108
chr3_+_174577070 0.46 ENST00000454872.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr6_-_119031228 0.46 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr10_+_6622345 0.46 ENST00000445427.1
ENST00000455810.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr9_-_125027079 0.45 ENST00000417201.3
RBM18
RNA binding motif protein 18
chr12_+_25205666 0.45 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr13_+_111766897 0.45 ENST00000317133.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr4_+_170581213 0.45 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr8_+_21916710 0.44 ENST00000523266.1
ENST00000519907.1
DMTN
dematin actin binding protein
chr3_-_46000064 0.44 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr6_+_1080164 0.44 ENST00000314040.1
AL033381.1
Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chr1_-_45805667 0.43 ENST00000488731.2
ENST00000435155.1
MUTYH
mutY homolog
chr18_+_5238055 0.43 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
LINC00667
long intergenic non-protein coding RNA 667
chr1_-_45805607 0.43 ENST00000372104.1
ENST00000448481.1
ENST00000483127.1
ENST00000528013.2
ENST00000456914.2
MUTYH
mutY homolog
chr11_+_3819049 0.43 ENST00000396986.2
ENST00000300730.6
ENST00000532535.1
ENST00000396993.4
ENST00000396991.2
ENST00000532523.1
ENST00000459679.1
ENST00000464261.1
ENST00000464906.2
ENST00000464441.1
PGAP2
post-GPI attachment to proteins 2
chr12_-_55367361 0.43 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1
thymocyte expressed, positive selection associated 1
chr12_-_90024360 0.43 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr12_+_498500 0.43 ENST00000540180.1
ENST00000422000.1
ENST00000535052.1
CCDC77
coiled-coil domain containing 77
chr11_-_35440579 0.43 ENST00000606205.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr16_+_24857552 0.43 ENST00000568579.1
ENST00000567758.1
ENST00000569071.1
ENST00000539472.1
SLC5A11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr5_-_10308125 0.42 ENST00000296658.3
CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
chrX_-_8139308 0.42 ENST00000317103.4
VCX2
variable charge, X-linked 2
chr19_+_34895289 0.41 ENST00000246535.3
PDCD2L
programmed cell death 2-like
chr5_+_125758865 0.41 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr1_+_22333943 0.41 ENST00000400271.2
CELA3A
chymotrypsin-like elastase family, member 3A
chr16_+_28770025 0.40 ENST00000435324.2
NPIPB9
nuclear pore complex interacting protein family, member B9
chr6_+_126277842 0.39 ENST00000229633.5
HINT3
histidine triad nucleotide binding protein 3
chr14_-_68066975 0.38 ENST00000559581.1
ENST00000560722.1
ENST00000559415.1
ENST00000216452.4
PIGH
phosphatidylinositol glycan anchor biosynthesis, class H
chr19_+_32836499 0.38 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chr19_+_34745442 0.38 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355
KIAA0355
chrX_+_49363665 0.38 ENST00000381700.6
GAGE1
G antigen 1
chr10_-_135379132 0.37 ENST00000343131.5
SYCE1
synaptonemal complex central element protein 1
chr1_+_95975672 0.37 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr3_+_88108381 0.37 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr2_-_71222466 0.37 ENST00000606025.1
AC007040.11
Uncharacterized protein
chr4_+_69681710 0.36 ENST00000265403.7
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr1_-_13452656 0.36 ENST00000376132.3
PRAMEF13
PRAME family member 13
chr9_-_125675576 0.36 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr5_+_98109322 0.36 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr15_+_101459420 0.36 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
LRRK1
leucine-rich repeat kinase 1
chr5_+_138677515 0.36 ENST00000265192.4
ENST00000511706.1
PAIP2
poly(A) binding protein interacting protein 2
chr7_-_22234381 0.36 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr1_-_198990166 0.35 ENST00000427439.1
RP11-16L9.3
RP11-16L9.3
chr19_+_58095501 0.35 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1
zinc finger protein interacting with K protein 1
chr2_+_103035102 0.35 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr5_+_5422778 0.35 ENST00000296564.7
KIAA0947
KIAA0947
chr12_-_498620 0.34 ENST00000399788.2
ENST00000382815.4
KDM5A
lysine (K)-specific demethylase 5A
chr6_+_31916733 0.34 ENST00000483004.1
CFB
complement factor B
chrX_-_6453159 0.34 ENST00000381089.3
ENST00000398729.1
VCX3A
variable charge, X-linked 3A
chr2_+_71357744 0.34 ENST00000498451.2
MPHOSPH10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr19_+_3933085 0.34 ENST00000168977.2
ENST00000599576.1
NMRK2
nicotinamide riboside kinase 2
chr12_+_25205446 0.34 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr6_+_136172820 0.33 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr7_-_38948774 0.33 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr17_+_41132564 0.33 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr11_-_118095718 0.33 ENST00000526620.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr1_-_58716197 0.33 ENST00000371234.4
DAB1
Dab, reelin signal transducer, homolog 1 (Drosophila)
chr5_+_138678131 0.33 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr4_-_74486347 0.32 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr11_+_6226782 0.32 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.4 1.3 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.4 1.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.4 1.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.4 1.4 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.3 1.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.3 1.5 GO:0072248 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2 0.7 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 1.3 GO:0015798 myo-inositol transport(GO:0015798)
0.2 1.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 1.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 1.2 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.3 GO:0010638 positive regulation of organelle organization(GO:0010638)
0.1 0.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 1.4 GO:0006477 protein sulfation(GO:0006477)
0.1 0.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.9 GO:0045007 depurination(GO:0045007)
0.1 9.4 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.3 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 2.3 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 1.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.3 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 0.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.6 GO:0036343 psychomotor behavior(GO:0036343)
0.1 2.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.6 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.2 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 1.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.3 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.9 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.5 GO:0015705 iodide transport(GO:0015705)
0.1 0.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.8 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 2.1 GO:0010107 potassium ion import(GO:0010107)
0.0 2.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 4.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 3.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.3 GO:2001023 regulation of response to drug(GO:2001023)
0.0 2.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0015824 proline transport(GO:0015824)
0.0 0.5 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 3.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0045796 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.0 0.7 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.3 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 1.8 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.0 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 2.4 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.4 GO:0036035 osteoclast development(GO:0036035)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 1.3 GO:0001942 hair follicle development(GO:0001942)
0.0 0.9 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.9 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.4 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 1.4 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0097224 sperm connecting piece(GO:0097224)
0.5 1.5 GO:0005608 laminin-3 complex(GO:0005608)
0.2 1.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 4.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.7 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.2 1.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 1.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.4 GO:0042611 MHC protein complex(GO:0042611)
0.1 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 4.2 GO:0005844 polysome(GO:0005844)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.7 GO:0097227 sperm annulus(GO:0097227)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 2.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.4 GO:0035580 specific granule lumen(GO:0035580)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.3 2.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 0.8 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.2 0.7 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 0.9 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.2 1.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 0.7 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 0.8 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 2.1 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 1.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.4 GO:0031013 troponin I binding(GO:0031013)
0.1 2.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 3.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 6.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.3 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 0.3 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 0.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 2.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 10.4 GO:0005178 integrin binding(GO:0005178)
0.1 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 4.0 GO:0019843 rRNA binding(GO:0019843)
0.0 1.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139) promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.5 GO:0042623 ATPase activity, coupled(GO:0042623) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.3 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.1 ST ADRENERGIC Adrenergic Pathway
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 6.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 4.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 2.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.9 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation