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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SOX6

Z-value: 0.56

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Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
SOX6
ENSG00000110693.11 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX6hg19_v2_chr11_-_16430399_16430440-0.261.6e-01Click!

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_180018540 3.58 ENST00000292641.3
SCGB3A1
secretoglobin, family 3A, member 1
chr4_+_70861647 2.60 ENST00000246895.4
ENST00000381060.2
STATH
statherin
chr16_+_23765948 2.16 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr20_-_39317868 1.99 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr10_+_115511213 1.98 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr5_+_140213815 1.90 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr5_+_140254884 1.56 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr14_-_106926724 1.56 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr12_-_49582978 1.46 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr2_-_86564776 1.42 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr13_+_24144796 1.31 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr6_-_29527702 1.31 ENST00000377050.4
UBD
ubiquitin D
chr4_+_41614909 1.21 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr13_+_24144509 1.19 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr4_+_55524085 1.04 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr6_-_139613269 1.03 ENST00000358430.3
TXLNB
taxilin beta
chr18_+_6729698 1.00 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr3_+_181429704 0.99 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr2_-_217560248 0.99 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr19_-_18717627 0.94 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr5_+_140235469 0.84 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr4_+_41614720 0.84 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr10_-_13390270 0.82 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1
chr2_+_232573208 0.78 ENST00000409115.3
PTMA
prothymosin, alpha
chr10_-_62332357 0.76 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_+_36317830 0.75 ENST00000530639.1
PRR5L
proline rich 5 like
chr8_+_24151553 0.75 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr9_-_130639997 0.74 ENST00000373176.1
AK1
adenylate kinase 1
chr6_-_134639180 0.74 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_149510553 0.71 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr2_+_232573222 0.71 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr22_+_39052632 0.69 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr2_-_118943930 0.68 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr11_-_76155618 0.68 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr1_+_14075865 0.68 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr8_+_24151620 0.67 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr12_-_50294033 0.67 ENST00000552669.1
FAIM2
Fas apoptotic inhibitory molecule 2
chr5_-_124081008 0.66 ENST00000306315.5
ZNF608
zinc finger protein 608
chr4_-_146101304 0.62 ENST00000447906.2
OTUD4
OTU domain containing 4
chr17_+_21729593 0.62 ENST00000581769.1
ENST00000584755.1
UBBP4
ubiquitin B pseudogene 4
chr3_-_148939835 0.61 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr15_+_74610894 0.60 ENST00000558821.1
ENST00000268082.4
CCDC33
coiled-coil domain containing 33
chr2_-_157198860 0.59 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_-_49582593 0.56 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr11_-_69519410 0.56 ENST00000294312.3
FGF19
fibroblast growth factor 19
chr18_+_13218769 0.56 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr3_-_114790179 0.55 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr17_-_56065484 0.55 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr9_-_130712995 0.54 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr2_+_61293021 0.53 ENST00000402291.1
KIAA1841
KIAA1841
chr1_+_14075903 0.52 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2
PR domain containing 2, with ZNF domain
chr2_+_27805880 0.50 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512
zinc finger protein 512
chr11_-_85430204 0.50 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr17_+_21729899 0.50 ENST00000583708.1
UBBP4
ubiquitin B pseudogene 4
chr11_-_75236867 0.50 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chrX_-_117107542 0.50 ENST00000371878.1
KLHL13
kelch-like family member 13
chr17_-_14683517 0.48 ENST00000379640.1
AC005863.1
AC005863.1
chr4_-_105416039 0.48 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr9_+_139874683 0.47 ENST00000444903.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr6_+_72596604 0.47 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr11_-_85430163 0.47 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr16_+_2083265 0.46 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr17_+_26698677 0.46 ENST00000457710.3
SARM1
sterile alpha and TIR motif containing 1
chr4_-_138453559 0.45 ENST00000511115.1
PCDH18
protocadherin 18
chr12_-_10151773 0.45 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr6_-_127840021 0.44 ENST00000465909.2
SOGA3
SOGA family member 3
chr11_-_76155700 0.44 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr15_-_52043722 0.43 ENST00000454181.2
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr6_-_24877490 0.43 ENST00000540914.1
ENST00000378023.4
FAM65B
family with sequence similarity 65, member B
chr10_+_70480963 0.42 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1
cell division cycle and apoptosis regulator 1
chr7_+_69064300 0.42 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr7_+_116312411 0.42 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr13_-_41593425 0.42 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chrX_+_130192318 0.42 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr6_+_122720681 0.41 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr15_+_89631647 0.41 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr6_-_127840336 0.41 ENST00000525778.1
SOGA3
SOGA family member 3
chr12_+_124997766 0.40 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr1_-_32801825 0.40 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr6_-_49712123 0.39 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr19_-_5340730 0.39 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS
protein tyrosine phosphatase, receptor type, S
chr8_+_105352050 0.39 ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr11_+_125365110 0.37 ENST00000527818.1
AP000708.1
AP000708.1
chr14_-_95236551 0.37 ENST00000238558.3
GSC
goosecoid homeobox
chr1_+_152943122 0.35 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr11_-_85430088 0.35 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr6_-_167040731 0.34 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr20_-_1317555 0.34 ENST00000537552.1
AL136531.1
HCG2043693; Uncharacterized protein
chr9_-_124989804 0.34 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr1_+_240255166 0.33 ENST00000319653.9
FMN2
formin 2
chr16_-_73082274 0.33 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr11_-_130184555 0.33 ENST00000525842.1
ZBTB44
zinc finger and BTB domain containing 44
chr6_-_3227877 0.33 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr3_+_112930306 0.33 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr18_-_52989217 0.33 ENST00000570287.2
TCF4
transcription factor 4
chr3_-_65583561 0.33 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr20_+_60718785 0.33 ENST00000421564.1
ENST00000450482.1
ENST00000331758.3
SS18L1
synovial sarcoma translocation gene on chromosome 18-like 1
chr11_-_130184470 0.33 ENST00000357899.4
ENST00000397753.1
ZBTB44
zinc finger and BTB domain containing 44
chr7_-_50628745 0.33 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr10_+_22605374 0.32 ENST00000448361.1
COMMD3
COMM domain containing 3
chr2_+_149402553 0.32 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr10_+_22605304 0.32 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr16_+_30205754 0.31 ENST00000354723.6
ENST00000355544.5
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_+_54964740 0.31 ENST00000394636.4
IRX5
iroquois homeobox 5
chr13_-_95131923 0.31 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr11_-_44971702 0.31 ENST00000533940.1
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr3_-_167813672 0.31 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr15_-_82338460 0.31 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr12_-_45270151 0.30 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr19_-_17571722 0.30 ENST00000301944.2
NXNL1
nucleoredoxin-like 1
chr15_+_89631381 0.30 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr16_-_30798492 0.29 ENST00000262525.4
ZNF629
zinc finger protein 629
chr1_+_244998602 0.29 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr10_+_35415851 0.29 ENST00000374726.3
CREM
cAMP responsive element modulator
chr12_-_45270077 0.28 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr5_+_139175380 0.28 ENST00000274710.3
PSD2
pleckstrin and Sec7 domain containing 2
chr16_+_68573640 0.28 ENST00000398253.2
ENST00000573161.1
ZFP90
ZFP90 zinc finger protein
chr22_+_29168652 0.27 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr7_+_29234101 0.27 ENST00000435288.2
CHN2
chimerin 2
chrX_+_129473859 0.27 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_+_29234028 0.26 ENST00000222792.6
CHN2
chimerin 2
chr19_-_10047219 0.26 ENST00000264833.4
OLFM2
olfactomedin 2
chr3_+_183353356 0.26 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24
kelch-like family member 24
chr5_+_140201183 0.26 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr5_+_134094461 0.25 ENST00000452510.2
ENST00000354283.4
DDX46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr17_-_9940058 0.25 ENST00000585266.1
GAS7
growth arrest-specific 7
chr14_-_96830207 0.25 ENST00000359933.4
ATG2B
autophagy related 2B
chr14_-_106518922 0.25 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr22_-_27014043 0.25 ENST00000215939.2
CRYBB1
crystallin, beta B1
chr11_-_94965667 0.24 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr12_-_95945246 0.24 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr21_+_33784670 0.24 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr14_+_23791159 0.23 ENST00000557702.1
PABPN1
poly(A) binding protein, nuclear 1
chr9_-_98269481 0.23 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1
patched 1
chr3_+_133118839 0.23 ENST00000302334.2
BFSP2
beaded filament structural protein 2, phakinin
chr18_+_13611763 0.23 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr16_-_15736881 0.23 ENST00000540441.2
KIAA0430
KIAA0430
chr15_+_52043758 0.22 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr15_-_54025300 0.22 ENST00000559418.1
WDR72
WD repeat domain 72
chr15_-_88799948 0.22 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr16_-_67970990 0.22 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr2_+_46926326 0.21 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr17_+_67498538 0.21 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_+_25264933 0.21 ENST00000401432.3
ENST00000403714.3
EFR3B
EFR3 homolog B (S. cerevisiae)
chr11_+_63706444 0.21 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr1_-_2461684 0.21 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr11_+_34654011 0.21 ENST00000531794.1
EHF
ets homologous factor
chr1_+_9005917 0.21 ENST00000549778.1
ENST00000480186.3
ENST00000377443.2
ENST00000377436.3
ENST00000377442.2
CA6
carbonic anhydrase VI
chr20_-_3996036 0.20 ENST00000336095.6
RNF24
ring finger protein 24
chr19_-_51891209 0.20 ENST00000221973.3
ENST00000596399.1
LIM2
lens intrinsic membrane protein 2, 19kDa
chrX_-_45060135 0.20 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr1_-_212004090 0.20 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr12_-_88974236 0.20 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr19_+_38397839 0.20 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr19_-_17571613 0.19 ENST00000594663.1
CTD-2521M24.10
Uncharacterized protein
chr17_-_18950310 0.19 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr12_-_76817036 0.19 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr9_-_88896977 0.19 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr1_+_24286287 0.19 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr18_-_74728998 0.19 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr15_-_41166414 0.19 ENST00000220507.4
RHOV
ras homolog family member V
chr3_+_112930387 0.19 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr9_+_108463234 0.18 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr6_+_13925098 0.18 ENST00000488300.1
ENST00000544682.1
ENST00000420478.2
RNF182
ring finger protein 182
chr4_-_87028478 0.18 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr7_-_128415844 0.18 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr1_-_21503337 0.18 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr5_-_173043591 0.17 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1
biorientation of chromosomes in cell division 1
chr12_-_89919220 0.17 ENST00000549035.1
ENST00000393179.4
POC1B
POC1 centriolar protein B
chr14_-_35344093 0.17 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr19_-_44124019 0.17 ENST00000300811.3
ZNF428
zinc finger protein 428
chr5_-_146435501 0.17 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chrX_+_135579238 0.17 ENST00000535601.1
ENST00000448450.1
ENST00000425695.1
HTATSF1
HIV-1 Tat specific factor 1
chr16_+_89989687 0.17 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
TUBB3
Tubulin beta-3 chain
chrX_+_129473916 0.17 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr5_-_146435572 0.16 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr1_+_200993071 0.16 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr12_+_25205666 0.16 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chrX_-_101726732 0.16 ENST00000457521.2
ENST00000412230.2
ENST00000453326.2
NXF2B
TCP11X2
nuclear RNA export factor 2B
t-complex 11 family, X-linked 2
chr5_-_114515734 0.16 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr5_+_49962772 0.16 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr16_-_31085033 0.16 ENST00000414399.1
ZNF668
zinc finger protein 668
chr10_-_32667660 0.15 ENST00000375110.2
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chrX_+_101470280 0.15 ENST00000395088.2
ENST00000330252.5
ENST00000333110.5
NXF2
TCP11X1
nuclear RNA export factor 2
t-complex 11 family, X-linked 1
chr17_+_4487294 0.15 ENST00000338859.4
SMTNL2
smoothelin-like 2
chr19_+_5681011 0.15 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr3_+_151986709 0.15 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr1_-_26324534 0.15 ENST00000374284.1
ENST00000441420.1
ENST00000374282.3
PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
chr3_-_8686479 0.15 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chr1_-_182360498 0.15 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr6_-_107436473 0.15 ENST00000369042.1
BEND3
BEN domain containing 3
chr4_-_68620053 0.15 ENST00000420975.2
ENST00000226413.4
GNRHR
gonadotropin-releasing hormone receptor
chr17_-_19648916 0.15 ENST00000444455.1
ENST00000439102.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr2_+_170590321 0.15 ENST00000392647.2
KLHL23
kelch-like family member 23
chr22_+_31160239 0.14 ENST00000445781.1
ENST00000401475.1
OSBP2
oxysterol binding protein 2
chr1_+_172502336 0.14 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chr21_+_38445539 0.14 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr4_-_186877502 0.14 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr18_+_13611431 0.14 ENST00000587757.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr17_-_19648683 0.13 ENST00000573368.1
ENST00000457500.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 1.0 GO:0038162 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.3 1.0 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.3 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 0.8 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.3 1.3 GO:0070842 aggresome assembly(GO:0070842)
0.2 0.9 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 0.6 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 0.8 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 2.6 GO:0046541 saliva secretion(GO:0046541)
0.1 3.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.4 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 1.0 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.3 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 1.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.9 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 2.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.2 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 1.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.2 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 1.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.2 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 1.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.5 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.5 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.7 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.3 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.4 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 5.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 2.3 GO:0001942 hair follicle development(GO:0001942)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.3 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.2 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.3 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 1.0 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 1.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.0 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0046848 hydroxyapatite binding(GO:0046848)
0.4 1.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 0.8 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.2 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 2.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.3 GO:0005119 smoothened binding(GO:0005119)
0.1 0.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 2.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors