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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SP100

Z-value: 0.83

Motif logo

Transcription factors associated with SP100

Gene Symbol Gene ID Gene Info
ENSG00000067066.12 SP100 nuclear antigen

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SP100hg19_v2_chr2_+_231280954_2312809810.193.2e-01Click!

Activity profile of SP100 motif

Sorted Z-values of SP100 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_16085314 4.93 ENST00000510224.1
prominin 1
chr3_-_197676740 3.82 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
IQ motif containing G
chr9_+_72435709 2.92 ENST00000377197.3
ENST00000527647.1
chromosome 9 open reading frame 135
chr6_+_88117683 2.37 ENST00000369562.4
UPF0704 protein C6orf165
chr6_-_33048483 2.36 ENST00000419277.1
major histocompatibility complex, class II, DP alpha 1
chr6_+_32407619 2.32 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr16_+_84209539 2.27 ENST00000569735.1
dynein, axonemal, assembly factor 1
chr7_-_100965011 2.06 ENST00000498704.2
ENST00000517481.1
ENST00000437644.2
ENST00000315322.4
RAB, member RAS oncogene family-like 5
chr11_-_5248294 1.97 ENST00000335295.4
hemoglobin, beta
chr2_+_183943464 1.87 ENST00000354221.4
dual specificity phosphatase 19
chr21_-_35884573 1.84 ENST00000399286.2
potassium voltage-gated channel, Isk-related family, member 1
chr6_+_135502408 1.78 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr6_-_52668605 1.72 ENST00000334575.5
glutathione S-transferase alpha 1
chr12_+_111051902 1.69 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
tectonic family member 1
chr2_+_39103103 1.57 ENST00000340556.6
ENST00000410014.1
ENST00000409665.1
ENST00000409077.2
ENST00000409131.2
MORN repeat containing 2
chr11_+_73661364 1.52 ENST00000339764.1
DnaJ (Hsp40) homolog, subfamily B, member 13
chr12_-_58329819 1.51 ENST00000551421.1
RP11-620J15.3
chr2_-_178417742 1.48 ENST00000408939.3
tetratricopeptide repeat domain 30B
chr20_-_45318230 1.46 ENST00000372114.3
TP53 regulating kinase
chr6_+_32709119 1.45 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr6_+_135502466 1.38 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog
chr1_+_47489240 1.36 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr1_+_63989004 1.33 ENST00000371088.4
EF-hand calcium binding domain 7
chr17_+_7761013 1.27 ENST00000571846.1
cytochrome b5 domain containing 1
chr19_+_4639514 1.26 ENST00000327473.4
tumor necrosis factor, alpha-induced protein 8-like 1
chr17_+_7761301 1.21 ENST00000332439.4
ENST00000570446.1
cytochrome b5 domain containing 1
chr5_+_35617940 1.19 ENST00000282469.6
ENST00000509059.1
ENST00000356031.3
ENST00000510777.1
sperm flagellar 2
chr5_+_140514782 1.09 ENST00000231134.5
protocadherin beta 5
chr8_+_94767072 1.07 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
transmembrane protein 67
chr3_+_113666748 1.01 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chr10_-_46167722 0.94 ENST00000374366.3
ENST00000344646.5
zinc finger, AN1-type domain 4
chrX_-_77395186 0.94 ENST00000341864.5
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr5_-_41261540 0.94 ENST00000263413.3
complement component 6
chr8_+_75262612 0.90 ENST00000220822.7
ganglioside induced differentiation associated protein 1
chr15_+_45879534 0.90 ENST00000564080.1
ENST00000562384.1
ENST00000569076.1
ENST00000566753.1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr10_-_29084886 0.88 ENST00000608061.1
ENST00000443246.2
ENST00000446012.1
long intergenic non-protein coding RNA 837
chr4_+_41540160 0.87 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chr19_-_10764509 0.86 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr15_+_66797627 0.85 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr3_-_122134882 0.84 ENST00000330689.4
WD repeat domain 5B
chr10_+_127661942 0.83 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr6_+_42847649 0.80 ENST00000424341.2
ENST00000602561.1
ribosomal protein L7-like 1
chr16_+_16484691 0.78 ENST00000344087.4
nuclear pore complex interacting protein family, member A7
chr21_+_40752170 0.78 ENST00000333781.5
ENST00000541890.1
tryptophan rich basic protein
chr12_+_122356488 0.78 ENST00000397454.2
WD repeat domain 66
chr12_-_25801478 0.77 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
intermediate filament tail domain containing 1
chr15_-_45670924 0.77 ENST00000396659.3
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr7_-_120498357 0.74 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr12_+_123459127 0.74 ENST00000397389.2
ENST00000538755.1
ENST00000536150.1
ENST00000545056.1
ENST00000545612.1
ENST00000538628.1
ENST00000545317.1
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr2_-_28113965 0.74 ENST00000302188.3
ribokinase
chr12_-_42877726 0.74 ENST00000548696.1
prickle homolog 1 (Drosophila)
chr15_-_93632421 0.72 ENST00000329082.7
repulsive guidance molecule family member a
chr12_+_120884222 0.71 ENST00000551765.1
ENST00000229384.5
glutamyl-tRNA(Gln) amidotransferase, subunit C
chr4_+_128802016 0.70 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
polo-like kinase 4
chr2_+_183989083 0.69 ENST00000295119.4
nucleoporin 35kDa
chr13_+_25254545 0.69 ENST00000218548.6
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr11_-_77790865 0.69 ENST00000534029.1
ENST00000525085.1
ENST00000527806.1
ENST00000528164.1
ENST00000528251.1
ENST00000530054.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NDUFC2-KCTD14 readthrough
chr1_-_234614849 0.68 ENST00000040877.1
TAR (HIV-1) RNA binding protein 1
chr18_-_52989525 0.68 ENST00000457482.3
transcription factor 4
chr11_-_77791156 0.68 ENST00000281031.4
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
chr21_+_40759684 0.68 ENST00000380708.1
tryptophan rich basic protein
chr11_-_5255696 0.66 ENST00000292901.3
ENST00000417377.1
hemoglobin, delta
chr4_+_89299994 0.66 ENST00000264346.7
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_-_45883558 0.66 ENST00000445698.1
ENST00000296135.6
leucine zipper transcription factor-like 1
chr15_+_66797455 0.66 ENST00000446801.2
zwilch kinetochore protein
chr2_+_183989157 0.65 ENST00000541912.1
nucleoporin 35kDa
chr8_+_110552831 0.64 ENST00000530629.1
estrogen receptor binding site associated, antigen, 9
chr17_+_17876127 0.64 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr6_-_109804412 0.62 ENST00000230122.3
zinc finger and BTB domain containing 24
chrX_-_153707246 0.61 ENST00000407062.1
L antigen family, member 3
chr11_-_17410869 0.60 ENST00000528731.1
potassium inwardly-rectifying channel, subfamily J, member 11
chr5_+_148651409 0.60 ENST00000296721.4
actin filament associated protein 1-like 1
chr3_+_130745688 0.60 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NIMA-related kinase 11
chr6_+_29691056 0.59 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
major histocompatibility complex, class I, F
chr1_-_160001737 0.59 ENST00000368090.2
phosphatidylinositol glycan anchor biosynthesis, class M
chr15_-_93616340 0.59 ENST00000557420.1
ENST00000542321.2
repulsive guidance molecule family member a
chr3_-_11685345 0.58 ENST00000430365.2
vestigial like 4 (Drosophila)
chr6_-_119256311 0.58 ENST00000316316.6
minichromosome maintenance complex component 9
chr1_+_227751231 0.58 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
zinc finger protein 678
chr10_+_38299546 0.58 ENST00000374618.3
ENST00000432900.2
ENST00000458705.2
ENST00000469037.2
zinc finger protein 33A
chr16_+_66914264 0.57 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr14_-_24911448 0.57 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
short chain dehydrogenase/reductase family 39U, member 1
chr7_-_117513540 0.56 ENST00000160373.3
cortactin binding protein 2
chr18_-_52989217 0.56 ENST00000570287.2
transcription factor 4
chr6_-_110011718 0.56 ENST00000532976.1
adenylate kinase 9
chrX_-_153707545 0.56 ENST00000357360.4
L antigen family, member 3
chr8_+_75262629 0.56 ENST00000434412.2
ganglioside induced differentiation associated protein 1
chr6_+_135502501 0.55 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr1_-_109203997 0.55 ENST00000370032.5
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr1_+_15272271 0.54 ENST00000400797.3
kazrin, periplakin interacting protein
chrX_-_10588459 0.53 ENST00000380782.2
midline 1 (Opitz/BBB syndrome)
chr7_-_32529973 0.53 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_46859933 0.53 ENST00000243167.8
fatty acid amide hydrolase
chr13_+_114462193 0.52 ENST00000375353.3
transmembrane protein 255B
chr6_+_29691198 0.52 ENST00000440587.2
ENST00000434407.2
major histocompatibility complex, class I, F
chr3_+_62304648 0.51 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
chromosome 3 open reading frame 14
chr17_+_16284604 0.51 ENST00000395839.1
ENST00000395837.1
ubiquitin B
chr12_+_104682496 0.51 ENST00000378070.4
thioredoxin reductase 1
chr1_+_13521973 0.51 ENST00000327795.5
PRAME family member 21
chr3_-_43147549 0.50 ENST00000344697.2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr14_-_75530693 0.50 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
acylphosphatase 1, erythrocyte (common) type
chr1_+_2487800 0.50 ENST00000355716.4
tumor necrosis factor receptor superfamily, member 14
chr12_-_110841462 0.50 ENST00000455511.3
ENST00000450008.2
anaphase promoting complex subunit 7
chr8_+_110552337 0.49 ENST00000337573.5
estrogen receptor binding site associated, antigen, 9
chr1_+_231473743 0.49 ENST00000295050.7
SprT-like N-terminal domain
chr11_-_76381781 0.49 ENST00000260061.5
ENST00000404995.1
leucine rich repeat containing 32
chr17_-_62502022 0.48 ENST00000578804.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr9_-_126030817 0.48 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
spermatid perinuclear RNA binding protein
chr6_-_167571817 0.47 ENST00000366834.1
G protein-coupled receptor 31
chrX_-_10588595 0.47 ENST00000423614.1
ENST00000317552.4
midline 1 (Opitz/BBB syndrome)
chr9_-_135754164 0.47 ENST00000298545.3
adenylate kinase 8
chr14_-_24912047 0.47 ENST00000553930.1
short chain dehydrogenase/reductase family 39U, member 1
chr2_-_89399845 0.46 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr19_+_32896646 0.46 ENST00000392250.2
dpy-19-like 3 (C. elegans)
chr14_-_102605983 0.46 ENST00000334701.7
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr16_+_84209738 0.45 ENST00000564928.1
dynein, axonemal, assembly factor 1
chr6_-_13486369 0.45 ENST00000558378.1
AL583828.1
chr17_-_4544960 0.45 ENST00000293761.3
arachidonate 15-lipoxygenase
chr14_-_24911868 0.45 ENST00000554698.1
short chain dehydrogenase/reductase family 39U, member 1
chr5_-_76383133 0.45 ENST00000255198.2
zinc finger, BED-type containing 3
chr15_+_72410629 0.44 ENST00000340912.4
ENST00000544171.1
SUMO/sentrin specific peptidase family member 8
chr19_+_56989609 0.44 ENST00000601875.1
ZNF667 antisense RNA 1 (head to head)
chr20_+_42219559 0.44 ENST00000373030.3
ENST00000373039.4
intraflagellar transport 52 homolog (Chlamydomonas)
chr10_+_91174314 0.44 ENST00000371795.4
interferon-induced protein with tetratricopeptide repeats 5
chr13_-_31736132 0.44 ENST00000429785.2
heat shock 105kDa/110kDa protein 1
chr6_-_131949200 0.43 ENST00000539158.1
ENST00000368058.1
mediator complex subunit 23
chr9_-_135230336 0.42 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
senataxin
chr17_-_62502399 0.42 ENST00000450599.2
ENST00000585060.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr16_-_28303360 0.42 ENST00000501520.1
RP11-57A19.2
chr14_+_22446680 0.42 ENST00000390443.3
T cell receptor alpha variable 8-6
chr13_-_31736027 0.41 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
heat shock 105kDa/110kDa protein 1
chr9_-_97402531 0.41 ENST00000415431.1
fructose-1,6-bisphosphatase 1
chr2_+_179149636 0.41 ENST00000409631.1
oxysterol binding protein-like 6
chr7_-_156685841 0.40 ENST00000354505.4
ENST00000540390.1
limb development membrane protein 1
chr1_-_39339777 0.40 ENST00000397572.2
MYC binding protein
chr10_-_61495760 0.39 ENST00000395347.1
solute carrier family 16, member 9
chr14_+_105957402 0.39 ENST00000421892.1
ENST00000334656.7
ENST00000451719.1
ENST00000392522.3
ENST00000392523.4
ENST00000354560.6
ENST00000450383.1
chromosome 14 open reading frame 80
chr19_+_54024251 0.39 ENST00000253144.9
zinc finger protein 331
chr14_-_24911971 0.39 ENST00000555365.1
ENST00000399395.3
short chain dehydrogenase/reductase family 39U, member 1
chr3_-_15106747 0.38 ENST00000449354.2
ENST00000444840.2
ENST00000253686.2
mitochondrial ribosomal protein S25
chr6_+_32812568 0.38 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr10_+_60272814 0.38 ENST00000373886.3
bicaudal C homolog 1 (Drosophila)
chr9_-_97402413 0.38 ENST00000414122.1
fructose-1,6-bisphosphatase 1
chr10_+_35416223 0.37 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chrX_+_144908928 0.37 ENST00000408967.2
transmembrane protein 257
chr3_+_119187785 0.37 ENST00000295588.4
ENST00000476573.1
protein O-glucosyltransferase 1
chr12_+_4758264 0.37 ENST00000266544.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr4_+_159690218 0.37 ENST00000264433.6
folliculin interacting protein 2
chrX_+_77154935 0.36 ENST00000481445.1
cytochrome c oxidase subunit VIIb
chr6_+_41888926 0.36 ENST00000230340.4
bystin-like
chr10_+_51187938 0.36 ENST00000311663.5
family with sequence similarity 21, member D
chr3_-_186288097 0.36 ENST00000446782.1
TBCC domain containing 1
chr6_+_10585979 0.36 ENST00000265012.4
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr16_-_4664860 0.36 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBA-like domain containing 1
chr2_+_38893208 0.36 ENST00000410063.1
galactose mutarotase (aldose 1-epimerase)
chr4_+_40058411 0.36 ENST00000261435.6
ENST00000515550.1
NEDD4 binding protein 2
chr2_-_70418032 0.35 ENST00000425268.1
ENST00000428751.1
ENST00000417203.1
ENST00000417865.1
ENST00000428010.1
ENST00000447804.1
ENST00000264434.2
chromosome 2 open reading frame 42
chr11_-_76381029 0.35 ENST00000407242.2
ENST00000421973.1
leucine rich repeat containing 32
chr16_-_30441293 0.35 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
dCTP pyrophosphatase 1
chr2_+_39005336 0.35 ENST00000409566.1
gem (nuclear organelle) associated protein 6
chr4_+_89299885 0.35 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr16_-_68057770 0.35 ENST00000332395.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chrX_+_36246735 0.35 ENST00000378653.3
chromosome X open reading frame 30
chr22_+_32455111 0.35 ENST00000543737.1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr14_-_102552659 0.35 ENST00000441629.2
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr8_+_39442097 0.35 ENST00000265707.5
ENST00000379866.1
ENST00000520772.1
ENST00000541111.1
ADAM metallopeptidase domain 18
chr14_-_21490417 0.35 ENST00000556366.1
NDRG family member 2
chrX_+_11129388 0.34 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr2_+_189156586 0.34 ENST00000409830.1
GULP, engulfment adaptor PTB domain containing 1
chr2_-_111334678 0.34 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
RANBP2-like and GRIP domain containing 6
chr14_-_21490653 0.34 ENST00000449431.2
NDRG family member 2
chr6_+_158957431 0.34 ENST00000367090.3
transmembrane protein 181
chr15_+_93749295 0.34 ENST00000599897.1
AC112693.2
chr9_-_32526184 0.33 ENST00000545044.1
ENST00000379868.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chrX_+_108780347 0.33 ENST00000372103.1
nuclear transport factor 2-like export factor 2
chr5_+_98104978 0.33 ENST00000308234.7
repulsive guidance molecule family member b
chr17_+_21030260 0.33 ENST00000579303.1
dehydrogenase/reductase (SDR family) member 7B
chr4_+_69962185 0.32 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr2_-_152118352 0.32 ENST00000331426.5
RNA binding motif protein 43
chr19_+_52901094 0.32 ENST00000391788.2
ENST00000436397.1
ENST00000391787.2
ENST00000360465.3
ENST00000494167.2
ENST00000493272.1
zinc finger protein 528
chr14_-_20774092 0.32 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
tetratricopeptide repeat domain 5
chr9_-_99775862 0.32 ENST00000602917.1
ENST00000375223.4
hippocampus abundant transcript-like 2
chr9_-_139343294 0.32 ENST00000313084.5
SEC16 homolog A (S. cerevisiae)
chr11_-_31531121 0.31 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr6_-_131949305 0.31 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
mediator complex subunit 23
chr15_+_90777424 0.30 ENST00000561433.1
ENST00000559204.1
ENST00000558291.1
GDP-D-glucose phosphorylase 1
chr11_+_7626950 0.30 ENST00000530181.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr13_-_31736478 0.30 ENST00000445273.2
heat shock 105kDa/110kDa protein 1
chr14_-_21490590 0.30 ENST00000557633.1
NDRG family member 2
chrX_+_70586140 0.30 ENST00000276072.3
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr1_-_167883327 0.30 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
adenylate cyclase 10 (soluble)
chr5_+_40841276 0.30 ENST00000254691.5
caspase recruitment domain family, member 6
chr7_+_12610307 0.29 ENST00000297029.5
scinderin
chr2_-_55920952 0.29 ENST00000447944.2
polyribonucleotide nucleotidyltransferase 1
chr19_+_56159362 0.29 ENST00000593069.1
ENST00000308964.3
coiled-coil domain containing 106
chr6_-_41888814 0.29 ENST00000409060.1
ENST00000265350.4
mediator complex subunit 20
chr19_+_21688366 0.28 ENST00000358491.4
ENST00000597078.1
zinc finger protein 429
chr22_-_20307532 0.28 ENST00000405465.3
ENST00000248879.3
DiGeorge syndrome critical region gene 6-like
chrX_-_20159934 0.28 ENST00000379593.1
ENST00000379607.5
eukaryotic translation initiation factor 1A, X-linked
chr9_-_33264557 0.28 ENST00000473781.1
ENST00000488499.1
BCL2-associated athanogene

Network of associatons between targets according to the STRING database.

First level regulatory network of SP100

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.2 4.9 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.6 2.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.5 2.0 GO:0030185 nitric oxide transport(GO:0030185)
0.5 2.7 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.4 3.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.3 1.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 1.7 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.2 0.7 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2 0.9 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 0.7 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 0.2 GO:0018307 enzyme active site formation(GO:0018307)
0.2 1.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.2 0.8 GO:0043335 protein unfolding(GO:0043335)
0.2 0.8 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 0.6 GO:0006186 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.2 0.7 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.4 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.1 0.7 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 1.2 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.7 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.4 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 2.0 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 1.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.3 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 0.4 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 0.3 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.5 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 1.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 1.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.4 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.2 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.5 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.4 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 0.8 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.0 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 0.4 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 1.0 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.9 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.3 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.1 1.1 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.5 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.2 GO:0034059 response to anoxia(GO:0034059)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.6 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.3 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 1.4 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.3 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.2 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.2 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.3 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.7 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 1.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.9 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 2.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.7 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 3.5 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 1.3 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0090212 vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 1.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.4 GO:0031334 positive regulation of protein complex assembly(GO:0031334)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.0 1.0 GO:0003341 cilium movement(GO:0003341)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.3 GO:0006413 translational initiation(GO:0006413)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:0021591 ventricular system development(GO:0021591)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.5 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.7 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 2.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.0 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.0 1.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.3 GO:0070646 protein deubiquitination(GO:0016579) protein modification by small protein removal(GO:0070646)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0002177 manchette(GO:0002177)
0.5 2.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.5 GO:1990423 RZZ complex(GO:1990423)
0.4 2.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 6.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 4.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 0.8 GO:0001534 radial spoke(GO:0001534)
0.2 0.7 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 0.7 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 2.8 GO:0036038 MKS complex(GO:0036038)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 0.4 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.1 GO:0042612 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.1 1.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.2 GO:0030849 autosome(GO:0030849)
0.1 0.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.1 GO:0000124 SAGA complex(GO:0000124)
0.1 1.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.7 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.9 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 4.4 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 2.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.6 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 3.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.4 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 2.0 GO:0030492 hemoglobin binding(GO:0030492)
0.3 3.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 0.5 GO:0004040 amidase activity(GO:0004040)
0.2 0.7 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.2 0.7 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.2 0.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.5 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.2 1.1 GO:0046979 TAP2 binding(GO:0046979)
0.2 1.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.4 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1 0.6 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 1.8 GO:0031433 telethonin binding(GO:0031433)
0.1 0.9 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.5 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 1.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.4 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.3 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.9 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 1.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.6 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 3.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 4.5 GO:0042805 actinin binding(GO:0042805)
0.1 0.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 2.3 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.4 GO:0070330 aromatase activity(GO:0070330)
0.1 3.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.1 GO:0031005 filamin binding(GO:0031005)
0.1 0.4 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 2.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0019784 SUMO-specific protease activity(GO:0016929) NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 1.1 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.2 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.7 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.8 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.5 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 2.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation