Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for SPI1

Z-value: 0.72

Motif logo

logo of

Transcription factors associated with SPI1

Gene Symbol Gene ID Gene Info
SPI1
ENSG00000066336.7 Spi-1 proto-oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPI1hg19_v2_chr11_-_47400062_47400077-0.193.3e-01Click!

Activity profile of SPI1 motif

Sorted Z-values of SPI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_114429997 1.89 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr10_+_94833642 1.85 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr2_+_233925064 1.84 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr6_-_34524049 1.48 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chr15_-_80263506 1.38 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr11_-_102826434 1.21 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr6_-_34524093 1.19 ENST00000544425.1
SPDEF
SAM pointed domain containing ETS transcription factor
chr2_-_161056762 1.01 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr1_-_205419053 0.92 ENST00000367154.1
LEMD1
LEM domain containing 1
chr2_-_161056802 0.89 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr7_-_27135591 0.88 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr11_+_65408273 0.85 ENST00000394227.3
SIPA1
signal-induced proliferation-associated 1
chr2_+_37571717 0.84 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr2_+_37571845 0.82 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr11_+_65407331 0.80 ENST00000527525.1
SIPA1
signal-induced proliferation-associated 1
chr2_+_228678550 0.78 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr1_-_114430169 0.75 ENST00000393316.3
BCL2L15
BCL2-like 15
chr7_+_129847688 0.75 ENST00000297819.3
SSMEM1
serine-rich single-pass membrane protein 1
chr7_+_123241908 0.73 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr8_+_124194875 0.72 ENST00000522648.1
ENST00000276699.6
FAM83A
family with sequence similarity 83, member A
chr12_-_51785182 0.72 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr8_-_42065187 0.70 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT
plasminogen activator, tissue
chr8_-_42065075 0.69 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT
plasminogen activator, tissue
chr6_+_33589161 0.69 ENST00000605930.1
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chr8_+_124194752 0.67 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr11_-_58343319 0.66 ENST00000395074.2
LPXN
leupaxin
chr17_-_47287928 0.65 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr17_+_38171681 0.64 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr17_+_38171614 0.64 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr3_-_16555150 0.62 ENST00000334133.4
RFTN1
raftlin, lipid raft linker 1
chr1_+_16083154 0.61 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr22_-_37640456 0.60 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr5_-_39270725 0.58 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr9_+_103204553 0.56 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_+_43766642 0.55 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_-_107642348 0.54 ENST00000393561.1
LAMB1
laminin, beta 1
chr16_-_30393752 0.53 ENST00000566517.1
ENST00000605106.1
SEPT1
SEPT1
septin 1
Uncharacterized protein
chr13_-_33760216 0.53 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr19_+_41257084 0.52 ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr22_-_37640277 0.51 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr4_+_8201091 0.51 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr16_+_55512742 0.51 ENST00000568715.1
ENST00000219070.4
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr8_+_74903580 0.50 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr3_-_112693865 0.50 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1
CD200 receptor 1
chr22_-_17489112 0.48 ENST00000400588.1
GAB4
GRB2-associated binding protein family, member 4
chr5_-_39203093 0.48 ENST00000515010.1
FYB
FYN binding protein
chr19_+_45281118 0.47 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr17_+_15848231 0.47 ENST00000304222.2
ADORA2B
adenosine A2b receptor
chr1_-_109618566 0.46 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr1_-_155948218 0.45 ENST00000313667.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr21_-_40685536 0.44 ENST00000341322.4
BRWD1
bromodomain and WD repeat domain containing 1
chr17_+_7461613 0.43 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr14_-_53417732 0.43 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chrX_-_153979315 0.43 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3
GRB2-associated binding protein 3
chr17_+_7482785 0.43 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68
CD68 molecule
chr16_-_30394143 0.42 ENST00000321367.3
ENST00000571393.1
SEPT1
septin 1
chr15_-_56209306 0.42 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr17_+_38599693 0.40 ENST00000542955.1
ENST00000269593.4
IGFBP4
insulin-like growth factor binding protein 4
chr6_-_43595039 0.40 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr12_+_6493406 0.39 ENST00000543190.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr3_-_50360192 0.39 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
HYAL2
hyaluronoglucosaminidase 2
chr12_+_53443963 0.39 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr12_+_53443680 0.39 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr6_-_42419649 0.39 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr1_+_209859510 0.39 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr9_+_116327326 0.38 ENST00000342620.5
RGS3
regulator of G-protein signaling 3
chr1_-_110933663 0.38 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr1_-_110933611 0.38 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr14_-_67859422 0.38 ENST00000556532.1
PLEK2
pleckstrin 2
chr10_-_71169031 0.38 ENST00000373307.1
TACR2
tachykinin receptor 2
chr9_+_139557360 0.38 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
EGFL7
EGF-like-domain, multiple 7
chr2_+_31456874 0.37 ENST00000541626.1
EHD3
EH-domain containing 3
chr12_+_101869096 0.37 ENST00000551346.1
SPIC
Spi-C transcription factor (Spi-1/PU.1 related)
chr17_-_29641084 0.37 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr2_-_192711968 0.37 ENST00000304141.4
SDPR
serum deprivation response
chr14_+_102276192 0.36 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr2_-_235405168 0.36 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr1_+_84609944 0.35 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr14_+_65171315 0.35 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr20_+_35201993 0.35 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr19_-_14224969 0.35 ENST00000589994.1
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr11_+_118175132 0.35 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr3_-_112693759 0.34 ENST00000440122.2
ENST00000490004.1
CD200R1
CD200 receptor 1
chr11_+_118175596 0.34 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr5_-_77844974 0.33 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr12_+_6493319 0.33 ENST00000536876.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr22_-_37545972 0.33 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr6_+_20403997 0.32 ENST00000535432.1
E2F3
E2F transcription factor 3
chr11_+_844406 0.32 ENST00000397404.1
TSPAN4
tetraspanin 4
chr3_-_71179988 0.32 ENST00000491238.1
FOXP1
forkhead box P1
chr15_-_33360342 0.32 ENST00000558197.1
FMN1
formin 1
chr16_-_67597789 0.32 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr12_+_20848486 0.32 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr17_-_39211463 0.31 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr12_-_51718436 0.31 ENST00000544402.1
BIN2
bridging integrator 2
chr3_+_47324424 0.31 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18
kelch-like family member 18
chr13_-_46756351 0.31 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr22_+_44577237 0.31 ENST00000415224.1
ENST00000417767.1
PARVG
parvin, gamma
chr9_+_116263639 0.31 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr9_+_116263778 0.30 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr2_+_96991935 0.30 ENST00000361124.4
ENST00000420728.1
ENST00000542887.1
ITPRIPL1
inositol 1,4,5-trisphosphate receptor interacting protein-like 1
chr19_+_41256764 0.30 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr16_-_2908155 0.30 ENST00000571228.1
ENST00000161006.3
PRSS22
protease, serine, 22
chr17_-_38545799 0.30 ENST00000577541.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr14_-_94421923 0.30 ENST00000555507.1
ASB2
ankyrin repeat and SOCS box containing 2
chr2_-_31360887 0.30 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr4_-_111119804 0.29 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr2_+_42104692 0.29 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr20_-_23030296 0.29 ENST00000377103.2
THBD
thrombomodulin
chr17_+_7461781 0.29 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_+_48577366 0.29 ENST00000316554.3
C12orf68
chromosome 12 open reading frame 68
chr3_-_71179699 0.29 ENST00000497355.1
FOXP1
forkhead box P1
chr17_+_7461580 0.29 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr20_+_43374421 0.28 ENST00000372861.3
KCNK15
potassium channel, subfamily K, member 15
chr21_-_28820892 0.28 ENST00000420186.2
AP001604.3
AP001604.3
chr8_+_86089460 0.28 ENST00000418930.2
E2F5
E2F transcription factor 5, p130-binding
chr11_+_66624527 0.28 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr9_-_136242909 0.28 ENST00000371991.3
ENST00000545297.1
SURF4
surfeit 4
chr17_+_7461849 0.28 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr1_-_118472171 0.28 ENST00000369442.3
GDAP2
ganglioside induced differentiation associated protein 2
chr1_-_155947951 0.28 ENST00000313695.7
ENST00000497907.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr18_+_21452964 0.28 ENST00000587184.1
LAMA3
laminin, alpha 3
chr6_-_32145861 0.28 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr16_-_2205352 0.28 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr8_+_27491572 0.28 ENST00000301904.3
SCARA3
scavenger receptor class A, member 3
chr2_-_64371546 0.27 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr7_+_112063192 0.27 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr4_+_37892682 0.27 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr7_+_74188309 0.27 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr4_-_138453606 0.27 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr10_-_121302195 0.27 ENST00000369103.2
RGS10
regulator of G-protein signaling 10
chr17_-_79269067 0.26 ENST00000288439.5
ENST00000374759.3
SLC38A10
solute carrier family 38, member 10
chr8_+_15397732 0.26 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
TUSC3
tumor suppressor candidate 3
chr11_+_118403747 0.26 ENST00000526853.1
TMEM25
transmembrane protein 25
chr3_+_25469802 0.26 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr1_+_236557569 0.26 ENST00000334232.4
EDARADD
EDAR-associated death domain
chr11_+_47270475 0.26 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr18_+_21452804 0.26 ENST00000269217.6
LAMA3
laminin, alpha 3
chr2_-_119605253 0.26 ENST00000295206.6
EN1
engrailed homeobox 1
chr16_-_28506840 0.25 ENST00000569430.1
CLN3
ceroid-lipofuscinosis, neuronal 3
chr3_+_25469724 0.25 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr3_-_195808980 0.25 ENST00000360110.4
TFRC
transferrin receptor
chr1_-_212588157 0.25 ENST00000261455.4
ENST00000535273.1
TMEM206
transmembrane protein 206
chr11_-_67120974 0.25 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr8_+_86089619 0.25 ENST00000256117.5
ENST00000416274.2
E2F5
E2F transcription factor 5, p130-binding
chr6_+_31543334 0.24 ENST00000449264.2
TNF
tumor necrosis factor
chr3_-_27498235 0.24 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr11_+_67219867 0.24 ENST00000438189.2
CABP4
calcium binding protein 4
chr3_-_195808952 0.24 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chrX_+_128913906 0.24 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr4_-_10686373 0.24 ENST00000442825.2
CLNK
cytokine-dependent hematopoietic cell linker
chr11_+_47270436 0.24 ENST00000395397.3
ENST00000405576.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr2_+_198669365 0.24 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr17_+_9728828 0.24 ENST00000262441.5
GLP2R
glucagon-like peptide 2 receptor
chr1_-_25256368 0.24 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr5_-_9546180 0.24 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr11_-_75141206 0.23 ENST00000376292.4
KLHL35
kelch-like family member 35
chr20_+_35201857 0.23 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr9_+_120466610 0.23 ENST00000394487.4
TLR4
toll-like receptor 4
chr15_+_90744533 0.23 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_+_154360476 0.23 ENST00000428397.2
OPRM1
opioid receptor, mu 1
chr12_-_123187890 0.23 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr15_+_64386261 0.23 ENST00000560829.1
SNX1
sorting nexin 1
chr12_-_54867352 0.23 ENST00000305879.5
GTSF1
gametocyte specific factor 1
chr11_-_3862059 0.23 ENST00000396978.1
RHOG
ras homolog family member G
chr2_-_96811170 0.23 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr11_-_124670273 0.23 ENST00000524950.1
ENST00000374979.3
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr11_-_72433346 0.23 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr12_-_123201337 0.23 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr2_-_190044480 0.22 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr19_+_17530838 0.22 ENST00000528659.1
ENST00000392702.2
ENST00000529939.1
MVB12A
multivesicular body subunit 12A
chr12_+_26274917 0.22 ENST00000538142.1
SSPN
sarcospan
chr11_+_131781290 0.22 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr14_-_45431091 0.22 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr5_-_175388327 0.22 ENST00000432305.2
ENST00000505969.1
THOC3
THO complex 3
chr1_-_247921982 0.22 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr1_-_155948318 0.22 ENST00000361247.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr21_-_48024986 0.22 ENST00000291700.4
ENST00000367071.4
S100B
S100 calcium binding protein B
chr7_-_75443118 0.22 ENST00000222902.2
CCL24
chemokine (C-C motif) ligand 24
chr10_-_100995540 0.22 ENST00000370546.1
ENST00000404542.1
HPSE2
heparanase 2
chrX_-_132549506 0.22 ENST00000370828.3
GPC4
glypican 4
chr3_+_147127142 0.21 ENST00000282928.4
ZIC1
Zic family member 1
chr18_+_21594585 0.21 ENST00000317571.3
TTC39C
tetratricopeptide repeat domain 39C
chr12_+_12938541 0.21 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr7_-_107443652 0.21 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr12_-_118797475 0.21 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr15_-_91565743 0.21 ENST00000535843.1
VPS33B
vacuolar protein sorting 33 homolog B (yeast)
chr18_-_59274139 0.21 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr1_+_236558694 0.21 ENST00000359362.5
EDARADD
EDAR-associated death domain
chr6_-_33548006 0.21 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr5_+_52856456 0.21 ENST00000296684.5
ENST00000506765.1
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr7_-_44229022 0.21 ENST00000403799.3
GCK
glucokinase (hexokinase 4)
chr11_-_124670550 0.21 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr5_+_133861790 0.21 ENST00000395003.1
PHF15
jade family PHD finger 2
chr6_-_33547975 0.21 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr6_-_32143828 0.21 ENST00000412465.2
ENST00000375107.3
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr6_+_154360616 0.20 ENST00000229768.5
ENST00000419506.2
ENST00000524163.1
ENST00000414028.2
ENST00000435918.2
ENST00000337049.4
OPRM1
opioid receptor, mu 1
chr11_-_32457075 0.20 ENST00000448076.3
WT1
Wilms tumor 1
chr6_+_154360553 0.20 ENST00000452687.2
OPRM1
opioid receptor, mu 1
chr22_+_37678424 0.20 ENST00000248901.6
CYTH4
cytohesin 4

Network of associatons between targets according to the STRING database.

First level regulatory network of SPI1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 1.7 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.5 1.9 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 2.7 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.3 1.7 GO:0042631 cellular response to water deprivation(GO:0042631)
0.3 0.8 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 0.9 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.2 2.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 0.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 0.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.6 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.1 0.7 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 0.4 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.7 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.7 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 1.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 1.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.4 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 0.6 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.9 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.4 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.2 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.1 1.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.4 GO:0019087 transformation of host cell by virus(GO:0019087)
0.1 0.6 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.9 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0046203 spermidine catabolic process(GO:0046203)
0.1 0.4 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.2 GO:0007566 embryo implantation(GO:0007566)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 1.7 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.3 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.6 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.2 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.2 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716) melanocyte proliferation(GO:0097325)
0.1 0.1 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.2 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 1.7 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.0 1.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0033590 response to cobalamin(GO:0033590)
0.0 0.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:2000416 regulation of eosinophil migration(GO:2000416)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.8 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:2000569 defense response to nematode(GO:0002215) T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.0 0.1 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.4 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.0 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642) plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.5 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.4 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0008355 olfactory learning(GO:0008355)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.2 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:0006226 dUMP biosynthetic process(GO:0006226) dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.6 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.3 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.0 0.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.0 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.0 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0002860 positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.0 GO:0097695 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.0 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 1.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.6 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.1 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 0.5 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.6 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.6 GO:0030897 HOPS complex(GO:0030897)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 1.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 0.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.4 1.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 1.8 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 0.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.5 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.6 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.4 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 0.8 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.4 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.4 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.1 0.4 GO:0030305 heparanase activity(GO:0030305)
0.1 0.6 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 1.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 1.7 GO:0051400 BH domain binding(GO:0051400)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.2 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.4 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.1 GO:0048406 neurotrophin receptor activity(GO:0005030) nerve growth factor receptor activity(GO:0010465) nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.3 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 2.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.7 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 2.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements