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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SPIC

Z-value: 0.93

Motif logo

Transcription factors associated with SPIC

Gene Symbol Gene ID Gene Info
ENSG00000166211.6 Spi-C transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIChg19_v2_chr12_+_101869096_1018691990.144.6e-01Click!

Activity profile of SPIC motif

Sorted Z-values of SPIC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_8201091 5.32 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3 domain and tetratricopeptide repeats 1
chr19_-_51471362 4.04 ENST00000376853.4
ENST00000424910.2
kallikrein-related peptidase 6
chr19_-_51471381 3.96 ENST00000594641.1
kallikrein-related peptidase 6
chr12_+_15699286 3.37 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
protein tyrosine phosphatase, receptor type, O
chr2_-_113594279 3.00 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr12_+_8975061 2.90 ENST00000299698.7
alpha-2-macroglobulin-like 1
chr3_-_111314230 2.70 ENST00000317012.4
zinc finger, BED-type containing 2
chr18_-_33077556 2.61 ENST00000589273.1
ENST00000586489.1
INO80 complex subunit C
chr4_-_80994471 2.57 ENST00000295465.4
anthrax toxin receptor 2
chr2_+_233925064 2.43 ENST00000359570.5
ENST00000538935.1
inositol polyphosphate-5-phosphatase, 145kDa
chr19_-_15344243 2.35 ENST00000602233.1
epoxide hydrolase 3
chr19_+_35645618 2.32 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr4_-_57547454 2.32 ENST00000556376.2
HOP homeobox
chr2_+_113885138 2.31 ENST00000409930.3
interleukin 1 receptor antagonist
chr19_-_51456344 2.28 ENST00000336334.3
ENST00000593428.1
kallikrein-related peptidase 5
chr19_-_51456321 2.26 ENST00000391809.2
kallikrein-related peptidase 5
chr15_-_80263506 2.19 ENST00000335661.6
BCL2-related protein A1
chr4_-_80994619 2.08 ENST00000404191.1
anthrax toxin receptor 2
chr19_-_51456198 2.06 ENST00000594846.1
kallikrein-related peptidase 5
chr1_-_43855444 1.96 ENST00000372455.4
mediator complex subunit 8
chr4_-_111119804 1.93 ENST00000394607.3
ENST00000302274.3
ELOVL fatty acid elongase 6
chr1_+_120839412 1.92 ENST00000355228.4
family with sequence similarity 72, member B
chr12_+_1800179 1.92 ENST00000357103.4
adiponectin receptor 2
chr19_+_35645817 1.89 ENST00000423817.3
FXYD domain containing ion transport regulator 5
chr1_+_151030234 1.78 ENST00000368921.3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr22_-_37880543 1.72 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_206138884 1.67 ENST00000341209.5
ENST00000607379.1
family with sequence similarity 72, member A
chr1_-_143913143 1.64 ENST00000400889.1
family with sequence similarity 72, member D
chr1_+_206138457 1.61 ENST00000367128.3
ENST00000431655.2
family with sequence similarity 72, member A
chr7_+_74188309 1.57 ENST00000289473.4
ENST00000433458.1
neutrophil cytosolic factor 1
chr1_+_203651937 1.56 ENST00000341360.2
ATPase, Ca++ transporting, plasma membrane 4
chr1_+_120839005 1.56 ENST00000369390.3
ENST00000452190.1
family with sequence similarity 72, member B
chr19_-_42927251 1.55 ENST00000597001.1
lipase, hormone-sensitive
chr1_-_27816556 1.52 ENST00000536657.1
WAS protein family, member 2
chr10_+_102106829 1.52 ENST00000370355.2
stearoyl-CoA desaturase (delta-9-desaturase)
chr16_+_23652773 1.49 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
dynactin 5 (p25)
chr6_+_106534192 1.48 ENST00000369091.2
ENST00000369096.4
PR domain containing 1, with ZNF domain
chr2_-_69098566 1.48 ENST00000295379.1
bone morphogenetic protein 10
chr16_+_30194916 1.46 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
coronin, actin binding protein, 1A
chr18_-_33077942 1.44 ENST00000334598.7
INO80 complex subunit C
chr2_-_238323007 1.44 ENST00000295550.4
collagen, type VI, alpha 3
chr5_+_96211643 1.41 ENST00000437043.3
ENST00000510373.1
endoplasmic reticulum aminopeptidase 2
chr1_+_192127578 1.40 ENST00000367460.3
regulator of G-protein signaling 18
chr11_+_68671310 1.39 ENST00000255078.3
ENST00000539224.1
immunoglobulin mu binding protein 2
chr12_+_120105558 1.38 ENST00000229328.5
ENST00000541640.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr5_-_39270725 1.37 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr10_-_98031265 1.35 ENST00000224337.5
ENST00000371176.2
B-cell linker
chr9_-_95640218 1.34 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
zinc finger protein 484
chr15_+_63354769 1.33 ENST00000558910.1
tropomyosin 1 (alpha)
chr3_+_47324424 1.32 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
kelch-like family member 18
chr1_-_6420737 1.28 ENST00000541130.1
ENST00000377845.3
acyl-CoA thioesterase 7
chr11_-_64647144 1.26 ENST00000359393.2
ENST00000433803.1
ENST00000411683.1
EH-domain containing 1
chr8_-_144655141 1.26 ENST00000398882.3
maestro heat-like repeat family member 6
chrX_-_107018969 1.25 ENST00000372383.4
TSC22 domain family, member 3
chr16_+_11439286 1.23 ENST00000312499.5
ENST00000576027.1
RecQ mediated genome instability 2
chr11_-_64851496 1.22 ENST00000404147.3
ENST00000275517.3
cell division cycle associated 5
chr1_-_154946825 1.21 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC (Src homology 2 domain containing) transforming protein 1
chr3_+_130613226 1.20 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATPase, Ca++ transporting, type 2C, member 1
chr10_-_98031310 1.18 ENST00000427367.2
ENST00000413476.2
B-cell linker
chr10_-_121302195 1.17 ENST00000369103.2
regulator of G-protein signaling 10
chr16_-_88851618 1.15 ENST00000301015.9
piezo-type mechanosensitive ion channel component 1
chr17_+_1959369 1.14 ENST00000576444.1
ENST00000322941.3
hypermethylated in cancer 1
chr5_+_33936491 1.13 ENST00000330120.3
relaxin/insulin-like family peptide receptor 3
chr15_+_90744533 1.13 ENST00000411539.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr11_-_1643368 1.11 ENST00000399682.1
keratin associated protein 5-4
chr10_-_75401500 1.11 ENST00000359322.4
myozenin 1
chr1_+_24645807 1.11 ENST00000361548.4
grainyhead-like 3 (Drosophila)
chr16_-_20702578 1.10 ENST00000307493.4
ENST00000219151.4
acyl-CoA synthetase medium-chain family member 1
chr17_-_37009882 1.08 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
ribosomal protein L23
chr9_+_116037922 1.07 ENST00000374198.4
pre-mRNA processing factor 4
chr20_-_54967187 1.05 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
aurora kinase A
chr3_+_130569592 1.04 ENST00000533801.2
ATPase, Ca++ transporting, type 2C, member 1
chr1_+_169337172 1.04 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
basic leucine zipper nuclear factor 1
chr2_+_48667983 1.04 ENST00000449090.2
protein phosphatase 1, regulatory subunit 21
chr1_-_150780757 1.04 ENST00000271651.3
cathepsin K
chr12_-_51785182 1.04 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr1_+_110091189 1.02 ENST00000369851.4
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr4_-_159094194 1.00 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr11_+_70244510 0.99 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
cortactin
chr1_-_24127256 0.98 ENST00000418277.1
UDP-galactose-4-epimerase
chr1_+_24645865 0.98 ENST00000342072.4
grainyhead-like 3 (Drosophila)
chr3_+_121796697 0.98 ENST00000482356.1
ENST00000393627.2
CD86 molecule
chr20_+_814377 0.97 ENST00000304189.2
ENST00000381939.1
family with sequence similarity 110, member A
chr17_-_43487741 0.97 ENST00000455881.1
Rho GTPase activating protein 27
chr10_+_112257596 0.97 ENST00000369583.3
dual specificity phosphatase 5
chr1_+_150245099 0.96 ENST00000369099.3
chromosome 1 open reading frame 54
chr4_-_80994210 0.95 ENST00000403729.2
anthrax toxin receptor 2
chr1_+_150245177 0.94 ENST00000369098.3
chromosome 1 open reading frame 54
chr19_+_19496728 0.94 ENST00000537887.1
ENST00000417582.2
GATA zinc finger domain containing 2A
chr2_+_48667898 0.94 ENST00000281394.4
ENST00000294952.8
protein phosphatase 1, regulatory subunit 21
chr1_-_47069886 0.94 ENST00000371946.4
ENST00000371945.4
ENST00000428112.2
ENST00000529170.1
MAP kinase interacting serine/threonine kinase 1
chr1_-_52499443 0.94 ENST00000371614.1
KTI12 homolog, chromatin associated (S. cerevisiae)
chr15_-_33360342 0.93 ENST00000558197.1
formin 1
chr1_+_11994715 0.92 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chrX_-_51239425 0.91 ENST00000375992.3
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr11_+_133938820 0.91 ENST00000299106.4
ENST00000529443.2
junctional adhesion molecule 3
chr16_+_30205225 0.91 ENST00000345535.4
ENST00000251303.6
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
chr12_-_49351228 0.90 ENST00000541959.1
ENST00000447318.2
ADP-ribosylation factor 3
chr9_-_134145880 0.90 ENST00000372269.3
ENST00000464831.1
family with sequence similarity 78, member A
chr12_-_54778471 0.90 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
zinc finger protein 385A
chr16_-_29465668 0.90 ENST00000569622.1
BolA-like protein 2
chr17_+_48450575 0.90 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
essential meiotic structure-specific endonuclease 1
chr12_-_7596735 0.89 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163 molecule-like 1
chr16_+_29465822 0.89 ENST00000330181.5
ENST00000351581.4
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr1_-_47069955 0.89 ENST00000341183.5
ENST00000496619.1
MAP kinase interacting serine/threonine kinase 1
chr15_-_34610962 0.88 ENST00000290209.5
solute carrier family 12 (potassium/chloride transporter), member 6
chr5_+_154393260 0.88 ENST00000435029.4
kinesin family member 4B
chrX_+_24072833 0.87 ENST00000253039.4
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr2_+_37458928 0.86 ENST00000439218.1
ENST00000432075.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr12_+_53693466 0.86 ENST00000267103.5
ENST00000548632.1
chromosome 12 open reading frame 10
chr3_-_28390120 0.85 ENST00000334100.6
5-azacytidine induced 2
chr10_-_75676400 0.84 ENST00000412307.2
chromosome 10 open reading frame 55
chr1_-_180991978 0.84 ENST00000542060.1
ENST00000258301.5
syntaxin 6
chr1_+_22979474 0.83 ENST00000509305.1
complement component 1, q subcomponent, B chain
chr3_+_52321827 0.82 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
glycerate kinase
chr4_-_99064387 0.82 ENST00000295268.3
sperm-tail PG-rich repeat containing 2
chr18_-_33077868 0.82 ENST00000590757.1
ENST00000592173.1
ENST00000441607.2
ENST00000587450.1
ENST00000589258.1
INO80 complex subunit C
Uncharacterized protein
chr11_-_102668879 0.81 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr14_-_69445968 0.81 ENST00000438964.2
actinin, alpha 1
chr1_+_212208919 0.80 ENST00000366991.4
ENST00000542077.1
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr12_-_113841678 0.80 ENST00000552280.1
ENST00000257549.4
serine dehydratase
chr12_-_77272765 0.78 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
cysteine and glycine-rich protein 2
chr19_+_41256764 0.77 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
small nuclear ribonucleoprotein polypeptide A
chr6_-_32145861 0.77 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr14_-_69446034 0.76 ENST00000193403.6
actinin, alpha 1
chr12_+_10658489 0.76 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr14_-_69445793 0.76 ENST00000538545.2
ENST00000394419.4
actinin, alpha 1
chrX_+_51075658 0.76 ENST00000356450.2
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr13_+_31309645 0.75 ENST00000380490.3
arachidonate 5-lipoxygenase-activating protein
chr19_+_38826477 0.75 ENST00000409410.2
ENST00000215069.4
catsper channel auxiliary subunit gamma
chrX_+_30233668 0.75 ENST00000378988.4
melanoma antigen family B, 2
chr4_-_99578776 0.74 ENST00000515287.1
tetraspanin 5
chrX_+_100075368 0.74 ENST00000415585.2
ENST00000372972.2
ENST00000413437.1
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr20_+_3869423 0.74 ENST00000497424.1
pantothenate kinase 2
chr14_+_67291158 0.74 ENST00000555456.1
gephyrin
chr22_+_37309662 0.74 ENST00000403662.3
ENST00000262825.5
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr5_+_110074685 0.73 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr4_-_74853897 0.73 ENST00000296028.3
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr3_-_179169330 0.73 ENST00000232564.3
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr5_+_115177178 0.72 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr3_-_28390298 0.72 ENST00000457172.1
5-azacytidine induced 2
chr3_-_138665969 0.72 ENST00000330315.3
forkhead box L2
chr1_-_109618566 0.72 ENST00000338366.5
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr8_-_8243968 0.71 ENST00000520004.1
Tyrosine-protein kinase SgK223
chr15_-_67546963 0.71 ENST00000561452.1
ENST00000261880.5
alpha- and gamma-adaptin binding protein
chr11_+_61891445 0.71 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
inner centromere protein antigens 135/155kDa
chr3_-_156272924 0.70 ENST00000467789.1
ENST00000265044.2
signal sequence receptor, gamma (translocon-associated protein gamma)
chr8_-_42623747 0.70 ENST00000534622.1
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr7_-_80551671 0.70 ENST00000419255.2
ENST00000544525.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chrX_-_153637612 0.69 ENST00000369807.1
ENST00000369808.3
deoxyribonuclease I-like 1
chr19_+_45417504 0.69 ENST00000588750.1
ENST00000588802.1
apolipoprotein C-I
chr11_+_72983246 0.69 ENST00000393590.2
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr6_-_136571400 0.69 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
mitochondrial fission regulator 2
chr13_+_41363581 0.68 ENST00000338625.4
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chr12_-_109915098 0.68 ENST00000542858.1
ENST00000542262.1
ENST00000424763.2
potassium channel tetramerization domain containing 10
chr2_-_70780572 0.68 ENST00000450929.1
transforming growth factor, alpha
chr18_-_61089665 0.68 ENST00000238497.5
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr7_-_99698338 0.68 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr1_-_24126892 0.67 ENST00000374497.3
ENST00000425913.1
UDP-galactose-4-epimerase
chr11_-_67120974 0.67 ENST00000539074.1
ENST00000312419.3
polymerase (DNA-directed), delta 4, accessory subunit
chr4_-_89152474 0.67 ENST00000515655.1
ATP-binding cassette, sub-family G (WHITE), member 2
chr1_+_22979676 0.67 ENST00000432749.2
ENST00000314933.6
complement component 1, q subcomponent, B chain
chr3_-_196014520 0.66 ENST00000441879.1
ENST00000292823.2
ENST00000411591.1
ENST00000431016.1
ENST00000443555.1
phosphate cytidylyltransferase 1, choline, alpha
chr6_-_27114577 0.66 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chr1_-_94147385 0.66 ENST00000260502.6
breast cancer anti-estrogen resistance 3
chr17_+_42925270 0.66 ENST00000253410.2
ENST00000587021.1
HIG1 hypoxia inducible domain family, member 1B
chr4_+_57333756 0.66 ENST00000510663.1
ENST00000504757.1
signal recognition particle 72kDa
chr3_-_50375657 0.65 ENST00000395126.3
Ras association (RalGDS/AF-6) domain family member 1
chr8_-_42623924 0.65 ENST00000276410.2
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr17_+_7482785 0.65 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68 molecule
chr1_+_33938236 0.64 ENST00000361328.3
ENST00000373413.2
zinc finger and SCAN domain containing 20
chr13_+_49280951 0.64 ENST00000282018.3
cysteinyl leukotriene receptor 2
chr1_-_9129735 0.64 ENST00000377424.4
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr20_-_1309809 0.64 ENST00000360779.3
syndecan binding protein (syntenin) 2
chr18_-_34408802 0.63 ENST00000590842.1
tubulin polyglutamylase complex subunit 2
chr3_-_28390415 0.63 ENST00000414162.1
ENST00000420543.2
5-azacytidine induced 2
chr11_-_85565906 0.62 ENST00000544076.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
chr11_+_65408273 0.62 ENST00000394227.3
signal-induced proliferation-associated 1
chr5_+_96079240 0.62 ENST00000515663.1
calpastatin
chr4_-_99578789 0.61 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr3_+_148847371 0.61 ENST00000296051.2
ENST00000460120.1
Hermansky-Pudlak syndrome 3
chr14_+_75469606 0.61 ENST00000266126.5
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr16_+_15737124 0.61 ENST00000396355.1
ENST00000396353.2
nudE neurodevelopment protein 1
chr19_+_1752372 0.61 ENST00000382349.4
one cut homeobox 3
chr9_-_36276966 0.60 ENST00000543356.2
ENST00000396594.3
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr12_-_95044309 0.60 ENST00000261226.4
transmembrane and coiled-coil domain family 3
chr16_-_72206034 0.60 ENST00000537465.1
ENST00000237353.10
polyamine modulated factor 1 binding protein 1
chr3_-_156272872 0.60 ENST00000476217.1
signal sequence receptor, gamma (translocon-associated protein gamma)
chr20_-_44540686 0.59 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
phospholipid transfer protein
chr5_+_74062806 0.59 ENST00000296802.5
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr1_-_161519682 0.59 ENST00000367969.3
ENST00000443193.1
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr2_-_101925055 0.59 ENST00000295317.3
ring finger protein 149
chr5_-_140013275 0.59 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14 molecule
chr16_+_23652700 0.59 ENST00000300087.2
dynactin 5 (p25)
chr20_-_48532046 0.58 ENST00000543716.1
spermatogenesis associated 2
chr1_-_175161890 0.58 ENST00000545251.2
ENST00000423313.1
KIAA0040
chr17_-_5138099 0.58 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr3_-_149095652 0.58 ENST00000305366.3
transmembrane 4 L six family member 1
chr17_-_76123101 0.58 ENST00000392467.3
transmembrane channel-like 6
chr19_+_38826415 0.58 ENST00000410018.1
ENST00000409235.3
catsper channel auxiliary subunit gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.1 3.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
1.1 6.6 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.0 3.0 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.8 2.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.5 1.6 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.5 2.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.5 1.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.5 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.5 2.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.4 1.2 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 0.4 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.4 1.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.4 8.0 GO:0016540 protein autoprocessing(GO:0016540)
0.4 1.1 GO:0060901 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.4 1.1 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.3 1.0 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.3 1.3 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.3 1.9 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.3 1.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 1.9 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.3 1.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 0.9 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 1.5 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.3 0.9 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.3 0.9 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.3 1.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 1.1 GO:0010266 response to vitamin B1(GO:0010266)
0.3 1.7 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3 1.4 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.3 2.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 1.9 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.3 2.4 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 1.3 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.7 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.7 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 0.7 GO:1903542 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.2 0.7 GO:0019085 early viral transcription(GO:0019085)
0.2 0.9 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 0.4 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 1.1 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 1.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 0.2 GO:0097242 beta-amyloid clearance(GO:0097242)
0.2 0.8 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 0.6 GO:0043473 pigmentation(GO:0043473)
0.2 0.8 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 0.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 1.2 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2 0.2 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.2 0.6 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 0.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 0.7 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 0.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.9 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.5 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.2 0.7 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.2 2.7 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.2 0.9 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.2 0.6 GO:0019086 late viral transcription(GO:0019086)
0.1 0.4 GO:0043318 negative regulation of dendritic cell antigen processing and presentation(GO:0002605) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.1 0.6 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.6 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.7 GO:0046203 spermidine catabolic process(GO:0046203)
0.1 0.7 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 1.0 GO:1990539 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.7 GO:0033686 oocyte growth(GO:0001555) positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.1 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.3 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 1.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.8 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 2.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.8 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.1 0.4 GO:0100009 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1 0.4 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 1.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.6 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.7 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 1.7 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.4 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 1.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.1 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.1 0.5 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.7 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.7 GO:1903376 neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376) negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.7 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 0.8 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 1.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 2.1 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.7 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.4 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.4 GO:2001191 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.8 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.7 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.4 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 1.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.5 GO:0032886 regulation of microtubule-based process(GO:0032886)
0.1 0.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 1.3 GO:0035878 nail development(GO:0035878)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 2.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.5 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152)
0.1 2.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.3 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 1.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.2 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.3 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.3 GO:0032680 tumor necrosis factor production(GO:0032640) regulation of tumor necrosis factor production(GO:0032680) regulation of tumor necrosis factor superfamily cytokine production(GO:1903555)
0.1 2.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.2 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 3.8 GO:1901998 toxin transport(GO:1901998)
0.1 0.1 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.2 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 0.7 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.2 GO:1905154 negative regulation of eosinophil activation(GO:1902567) negative regulation of membrane invagination(GO:1905154) negative regulation of eosinophil migration(GO:2000417)
0.1 1.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.4 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.0 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.7 GO:0015886 heme transport(GO:0015886) xenobiotic transport(GO:0042908)
0.1 0.2 GO:1904327 maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.1 0.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.8 GO:0000732 strand displacement(GO:0000732)
0.1 0.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.1 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 0.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.2 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.5 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.6 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.4 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.5 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.5 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.2 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 1.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.3 GO:0016050 vesicle organization(GO:0016050)
0.0 0.3 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.7 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:1903978 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.0 0.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) swimming behavior(GO:0036269)
0.0 0.2 GO:2000416 regulation of eosinophil migration(GO:2000416) positive regulation of eosinophil migration(GO:2000418)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 1.8 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0051126 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 2.1 GO:0060976 coronary vasculature development(GO:0060976)
0.0 1.0 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 1.4 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 0.5 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.6 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0019043 establishment of viral latency(GO:0019043)
0.0 0.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 1.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 1.2 GO:0097421 liver regeneration(GO:0097421)
0.0 0.5 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 1.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.7 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 1.0 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.6 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.2 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 1.0 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 1.3 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 2.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0 1.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.7 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424) beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.4 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.5 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 1.5 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.4 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.4 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 1.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 1.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0015866 ADP transport(GO:0015866)
0.0 3.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.1 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.8 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 1.4 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 1.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.4 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 1.6 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.0 0.1 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 1.1 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.4 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 3.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.1 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 1.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0006308 DNA catabolic process(GO:0006308)
0.0 1.2 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.4 1.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 1.5 GO:0005602 complement component C1 complex(GO:0005602)
0.3 1.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.3 1.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 1.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 1.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.9 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 1.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 0.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 0.8 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.2 2.6 GO:0005916 fascia adherens(GO:0005916)
0.2 0.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.3 GO:0036128 CatSper complex(GO:0036128)
0.2 0.7 GO:0055087 Ski complex(GO:0055087)
0.2 4.9 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.6 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.6 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.9 GO:0070847 core mediator complex(GO:0070847)
0.1 0.4 GO:0055028 cortical microtubule(GO:0055028)
0.1 1.2 GO:0008278 cohesin complex(GO:0008278)
0.1 2.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.4 GO:0032797 SMN complex(GO:0032797)
0.1 1.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 1.8 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 0.5 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.6 GO:0042588 zymogen granule(GO:0042588)
0.1 0.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.8 GO:0097443 sorting endosome(GO:0097443)
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 1.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.7 GO:0000801 central element(GO:0000801)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.1 0.6 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 1.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.6 GO:0016589 NURF complex(GO:0016589)
0.1 0.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 1.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.8 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.9 GO:0033010 paranodal junction(GO:0033010)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.4 GO:0044194 cytolytic granule(GO:0044194) alveolar lamellar body(GO:0097208)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 2.0 GO:0016592 mediator complex(GO:0016592)
0.1 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.0 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 1.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.3 GO:0031390 DNA replication factor C complex(GO:0005663) Ctf18 RFC-like complex(GO:0031390)
0.0 1.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 3.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.8 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 3.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 2.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 3.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.6 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 4.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 1.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.8 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 4.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0031968 organelle outer membrane(GO:0031968)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.6 2.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.5 1.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.5 1.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.4 1.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 1.7 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.4 2.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 0.9 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3 1.5 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 0.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3 0.9 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.3 1.7 GO:0052841 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.3 1.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 2.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 0.8 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.3 0.8 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.2 0.7 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 0.7 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.2 1.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 1.1 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 0.8 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 2.6 GO:0031433 telethonin binding(GO:0031433)
0.2 0.8 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.2 0.6 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 1.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 3.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.5 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 0.5 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.2 1.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 0.5 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2 3.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.0 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 1.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.1 GO:0005497 androgen binding(GO:0005497)
0.1 1.3 GO:0043426 MRF binding(GO:0043426)
0.1 1.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 2.7 GO:0051400 BH domain binding(GO:0051400)
0.1 1.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.7 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.8 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.7 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.3 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.4 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 1.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 3.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.6 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 2.3 GO:0017166 vinculin binding(GO:0017166)
0.1 0.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.3 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 1.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.5 GO:0005522 profilin binding(GO:0005522)
0.1 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.3 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.5 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.9 GO:0019864 IgG binding(GO:0019864)
0.1 0.8 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.4 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 1.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.4 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.3 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 3.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 1.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.0 4.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.5 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.7 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 13.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.6 GO:0031014 troponin T binding(GO:0031014)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 3.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 2.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 4.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0001032 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0070990 snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 2.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0035242 histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 8.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 5.3 PID IL3 PATHWAY IL3-mediated signaling events
0.1 4.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 2.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 1.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.9 PID MYC PATHWAY C-MYC pathway
0.0 1.8 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 8.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 2.1 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 1.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 7.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 3.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 2.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.4 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 2.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 2.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 3.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 5.4 REACTOME TRANSLATION Genes involved in Translation
0.0 2.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 2.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics