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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SRY

Z-value: 0.68

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Transcription factors associated with SRY

Gene Symbol Gene ID Gene Info
SRY
ENSG00000184895.6 sex determining region Y

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRYhg19_v2_chrY_-_2655644_2655740-0.105.9e-01Click!

Activity profile of SRY motif

Sorted Z-values of SRY motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_39564993 2.85 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr6_-_32557610 2.43 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr4_+_165675197 2.32 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr20_-_3762087 2.04 ENST00000379756.3
SPEF1
sperm flagellar 1
chr6_+_163148973 1.78 ENST00000366888.2
PACRG
PARK2 co-regulated
chr4_+_165675269 1.68 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr17_+_17876127 1.63 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48
leucine rich repeat containing 48
chr14_-_92413727 1.58 ENST00000267620.10
FBLN5
fibulin 5
chr1_+_61547405 1.36 ENST00000371189.4
NFIA
nuclear factor I/A
chr1_-_217311090 1.12 ENST00000493603.1
ENST00000366940.2
ESRRG
estrogen-related receptor gamma
chr14_-_92413353 1.04 ENST00000556154.1
FBLN5
fibulin 5
chr14_-_89883412 1.04 ENST00000557258.1
FOXN3
forkhead box N3
chr14_-_92414055 1.03 ENST00000342058.4
FBLN5
fibulin 5
chr4_-_105416039 1.02 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr1_-_40367668 1.02 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr2_-_157198860 0.97 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr6_-_152489484 0.94 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr14_-_23288930 0.91 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_-_72274095 0.91 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr1_-_217250231 0.87 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr1_+_33722080 0.86 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr14_+_53019993 0.85 ENST00000542169.2
ENST00000555622.1
GPR137C
G protein-coupled receptor 137C
chr5_-_111091948 0.83 ENST00000447165.2
NREP
neuronal regeneration related protein
chr20_-_21494654 0.82 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr6_+_126070726 0.81 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr19_+_13134772 0.80 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_-_56406117 0.79 ENST00000268893.6
ENST00000355701.3
BZRAP1
benzodiazepine receptor (peripheral) associated protein 1
chr10_-_62332357 0.73 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr5_+_140248518 0.73 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr1_-_160231451 0.69 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr22_-_31741757 0.69 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr6_-_9939552 0.66 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr10_+_99079008 0.65 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr14_+_91581011 0.65 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr13_+_113633620 0.64 ENST00000421756.1
ENST00000375601.3
MCF2L
MCF.2 cell line derived transforming sequence-like
chr14_-_61124977 0.62 ENST00000554986.1
SIX1
SIX homeobox 1
chr10_-_61900762 0.61 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_+_91580708 0.61 ENST00000518868.1
C14orf159
chromosome 14 open reading frame 159
chr10_-_99094458 0.60 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr4_+_41614909 0.60 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr14_+_91580777 0.60 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159
chromosome 14 open reading frame 159
chr17_+_8924837 0.60 ENST00000173229.2
NTN1
netrin 1
chr2_-_118943930 0.59 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr21_+_33784670 0.59 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr6_-_31651817 0.59 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr2_+_191273052 0.58 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6
major facilitator superfamily domain containing 6
chr3_-_11610255 0.58 ENST00000424529.2
VGLL4
vestigial like 4 (Drosophila)
chr10_-_62149433 0.58 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr16_-_68482440 0.57 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chrX_+_15525426 0.57 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr14_-_53019211 0.56 ENST00000557374.1
ENST00000281741.4
TXNDC16
thioredoxin domain containing 16
chr6_-_87804815 0.56 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr3_+_39509163 0.56 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chrX_-_24690771 0.56 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_-_57045228 0.56 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr17_-_39324424 0.55 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr12_-_10251576 0.54 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr5_-_146435501 0.53 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr18_-_52989217 0.52 ENST00000570287.2
TCF4
transcription factor 4
chr5_-_146435572 0.52 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr18_-_53303123 0.52 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr2_+_86668464 0.51 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr1_-_40367530 0.51 ENST00000372816.2
ENST00000372815.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr7_+_114055052 0.51 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr9_+_27109392 0.50 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr14_+_53019822 0.49 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr3_+_39509070 0.49 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr16_+_2588012 0.49 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr18_-_52989525 0.48 ENST00000457482.3
TCF4
transcription factor 4
chr13_-_41240717 0.47 ENST00000379561.5
FOXO1
forkhead box O1
chr5_-_146435694 0.45 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr18_+_72922710 0.45 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr3_-_141868357 0.45 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr18_-_53257027 0.45 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4
transcription factor 4
chr2_-_71454185 0.44 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr3_+_69812701 0.44 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr1_-_85930246 0.42 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_-_62359180 0.41 ENST00000283268.3
FEZF2
FEZ family zinc finger 2
chr16_+_2587998 0.41 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr3_+_112930306 0.41 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr1_-_177133818 0.41 ENST00000424564.2
ENST00000361833.2
ASTN1
astrotactin 1
chr1_-_177134024 0.40 ENST00000367654.3
ASTN1
astrotactin 1
chr17_+_79953310 0.40 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr9_-_124989804 0.40 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr11_-_85397167 0.40 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr20_+_11008408 0.39 ENST00000378252.1
C20orf187
chromosome 20 open reading frame 187
chr12_-_10251603 0.39 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr19_+_13135731 0.39 ENST00000587260.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_+_76311791 0.39 ENST00000586321.1
AC061992.2
AC061992.2
chr14_+_91580732 0.39 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
C14orf159
chromosome 14 open reading frame 159
chr20_+_10415931 0.38 ENST00000334534.5
SLX4IP
SLX4 interacting protein
chr8_+_110346546 0.37 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2
enhancer of yellow 2 homolog (Drosophila)
chr8_+_24151553 0.36 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr5_-_76935513 0.36 ENST00000306422.3
OTP
orthopedia homeobox
chr1_+_43855560 0.35 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr5_-_146461027 0.35 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr18_-_52969844 0.35 ENST00000561831.3
TCF4
transcription factor 4
chr10_-_13570533 0.35 ENST00000396900.2
ENST00000396898.2
BEND7
BEN domain containing 7
chr12_-_81763184 0.35 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr8_+_85095497 0.35 ENST00000522455.1
ENST00000521695.1
RALYL
RALY RNA binding protein-like
chr16_+_2587965 0.35 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr7_+_30185406 0.34 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr17_+_36861735 0.34 ENST00000378137.5
ENST00000325718.7
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr3_-_62358690 0.34 ENST00000475839.1
FEZF2
FEZ family zinc finger 2
chr21_-_19191703 0.33 ENST00000284881.4
ENST00000400559.3
ENST00000400558.3
C21orf91
chromosome 21 open reading frame 91
chr3_-_10332416 0.33 ENST00000450603.1
ENST00000449554.2
GHRL
ghrelin/obestatin prepropeptide
chr14_+_91580357 0.32 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
C14orf159
chromosome 14 open reading frame 159
chr9_+_84304628 0.32 ENST00000437181.1
RP11-154D17.1
RP11-154D17.1
chr6_+_139094657 0.32 ENST00000332797.6
CCDC28A
coiled-coil domain containing 28A
chr12_-_122985067 0.32 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr6_+_122720681 0.31 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr12_-_122985494 0.31 ENST00000336229.4
ZCCHC8
zinc finger, CCHC domain containing 8
chr1_+_164528866 0.31 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr7_-_19813192 0.31 ENST00000422233.1
ENST00000433641.1
TMEM196
transmembrane protein 196
chr1_-_108231101 0.30 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr19_+_13906250 0.30 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr16_-_4323015 0.30 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr3_-_58652523 0.30 ENST00000489857.1
ENST00000358781.2
FAM3D
family with sequence similarity 3, member D
chr3_+_112930387 0.30 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr11_+_36317830 0.30 ENST00000530639.1
PRR5L
proline rich 5 like
chr7_+_151038850 0.30 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr6_-_37665751 0.29 ENST00000297153.7
ENST00000434837.3
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr8_+_144295067 0.29 ENST00000330824.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr1_+_40840320 0.29 ENST00000372708.1
SMAP2
small ArfGAP2
chr9_-_37465396 0.29 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr19_+_13135790 0.29 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_147374915 0.28 ENST00000240986.4
GJA8
gap junction protein, alpha 8, 50kDa
chr19_-_47734448 0.28 ENST00000439096.2
BBC3
BCL2 binding component 3
chr12_-_10251539 0.28 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr22_+_19710468 0.27 ENST00000366425.3
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr11_-_82708519 0.27 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr2_-_152146385 0.27 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr6_-_79787902 0.26 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr6_+_72596604 0.26 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_227050079 0.25 ENST00000423838.1
AC068138.1
AC068138.1
chr10_+_111967345 0.25 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr4_+_71494461 0.25 ENST00000396073.3
ENAM
enamelin
chr12_+_498500 0.25 ENST00000540180.1
ENST00000422000.1
ENST00000535052.1
CCDC77
coiled-coil domain containing 77
chr8_+_85095769 0.25 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr1_-_115053781 0.25 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr4_+_170581213 0.25 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr2_+_135596180 0.24 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr1_+_33116765 0.24 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
RBBP4
retinoblastoma binding protein 4
chr15_-_54025300 0.24 ENST00000559418.1
WDR72
WD repeat domain 72
chrX_-_39923656 0.23 ENST00000413905.1
BCOR
BCL6 corepressor
chr2_-_133427767 0.23 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr8_+_24151620 0.23 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr11_-_118095718 0.22 ENST00000526620.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr5_-_24645078 0.22 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr11_+_112832202 0.22 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr2_+_109204743 0.22 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_+_137490748 0.22 ENST00000478772.1
RP11-2A4.3
RP11-2A4.3
chr6_+_157099036 0.22 ENST00000350026.5
ENST00000346085.5
ENST00000367148.1
ENST00000275248.4
ARID1B
AT rich interactive domain 1B (SWI1-like)
chr12_+_31477250 0.22 ENST00000313737.4
AC024940.1
AC024940.1
chr5_+_38148582 0.21 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr2_+_135596106 0.21 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr2_-_160472952 0.21 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr2_-_37899323 0.21 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr1_+_43855545 0.20 ENST00000372450.4
ENST00000310739.4
SZT2
seizure threshold 2 homolog (mouse)
chr5_+_138678131 0.20 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr9_-_123476612 0.20 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr7_-_92855762 0.20 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr7_+_29519486 0.20 ENST00000409041.4
CHN2
chimerin 2
chr14_+_58894103 0.20 ENST00000354386.6
ENST00000556134.1
KIAA0586
KIAA0586
chrX_-_74145273 0.20 ENST00000055682.6
KIAA2022
KIAA2022
chr2_+_86947296 0.19 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_-_160473114 0.19 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr19_-_46272462 0.19 ENST00000317578.6
SIX5
SIX homeobox 5
chr1_-_151119087 0.19 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr6_-_116381918 0.19 ENST00000606080.1
FRK
fyn-related kinase
chr15_-_86338100 0.19 ENST00000536947.1
KLHL25
kelch-like family member 25
chr17_-_73511584 0.18 ENST00000321617.3
CASKIN2
CASK interacting protein 2
chr13_-_38443860 0.18 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4
transient receptor potential cation channel, subfamily C, member 4
chr9_-_123476719 0.17 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr11_-_30608413 0.17 ENST00000528686.1
MPPED2
metallophosphoesterase domain containing 2
chr14_-_55878538 0.17 ENST00000247178.5
ATG14
autophagy related 14
chr1_+_235490659 0.17 ENST00000488594.1
GGPS1
geranylgeranyl diphosphate synthase 1
chr3_+_89156799 0.17 ENST00000452448.2
ENST00000494014.1
EPHA3
EPH receptor A3
chr4_+_41614720 0.17 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr11_-_118095801 0.17 ENST00000356289.5
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr17_-_46716647 0.17 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr13_-_99910673 0.17 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr8_-_145060593 0.16 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr15_-_86338134 0.16 ENST00000337975.5
KLHL25
kelch-like family member 25
chr10_-_32667660 0.15 ENST00000375110.2
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr1_+_41174988 0.15 ENST00000372652.1
NFYC
nuclear transcription factor Y, gamma
chr14_+_58894706 0.15 ENST00000261244.5
KIAA0586
KIAA0586
chr8_-_13134045 0.15 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr12_-_498620 0.15 ENST00000399788.2
ENST00000382815.4
KDM5A
lysine (K)-specific demethylase 5A
chr1_+_97188188 0.15 ENST00000541987.1
PTBP2
polypyrimidine tract binding protein 2
chr2_+_177028805 0.14 ENST00000249440.3
HOXD3
homeobox D3
chr14_+_58894141 0.14 ENST00000423743.3
KIAA0586
KIAA0586
chr2_+_27665232 0.14 ENST00000543753.1
ENST00000288873.3
KRTCAP3
keratinocyte associated protein 3
chr20_+_32150140 0.14 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr8_-_57123815 0.13 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chrX_+_84499038 0.13 ENST00000373165.3
ZNF711
zinc finger protein 711
chr15_-_88799948 0.13 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr2_+_27665289 0.13 ENST00000407293.1
KRTCAP3
keratinocyte associated protein 3
chr16_-_4852915 0.13 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr16_+_28858004 0.13 ENST00000322610.8
SH2B1
SH2B adaptor protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SRY

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.5 1.9 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 2.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.3 3.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 0.8 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 1.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 0.9 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0040010 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 1.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.5 GO:1902617 response to fluoride(GO:1902617)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.9 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.6 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.3 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 1.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 1.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.4 GO:0034627 quinolinate biosynthetic process(GO:0019805) 'de novo' NAD biosynthetic process(GO:0034627)
0.1 0.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.2 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 1.4 GO:0072189 ureter development(GO:0072189)
0.0 0.6 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 2.6 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 1.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.4 GO:0010827 regulation of glucose transport(GO:0010827) glucose import(GO:0046323) regulation of glucose import(GO:0046324)
0.0 0.1 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847) negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.4 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 2.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.4 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.0 GO:0006260 DNA replication(GO:0006260)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.8 GO:0007286 spermatid development(GO:0007286)
0.0 0.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155) fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0071953 elastic fiber(GO:0071953)
0.1 2.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 3.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.4 1.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.3 2.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 0.8 GO:0035939 microsatellite binding(GO:0035939)
0.2 2.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0031768 ghrelin receptor binding(GO:0031768)
0.1 2.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 1.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 1.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.8 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 3.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 3.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.8 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 2.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions