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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for STAT1_STAT3_BCL6
Z-value: 1.33
Motif logo
Transcription factors associated with STAT1_STAT3_BCL6
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
STAT1
|
ENSG00000115415.14 | signal transducer and activator of transcription 1 |
|
STAT3
|
ENSG00000168610.10 | signal transducer and activator of transcription 3 |
|
BCL6
|
ENSG00000113916.13 | BCL6 transcription repressor |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BCL6 | hg19_v2_chr3_-_187454281_187454357 | -0.32 | 8.0e-02 | Click! |
| STAT1 | hg19_v2_chr2_-_191878874_191878976 | 0.17 | 3.7e-01 | Click! |
| STAT3 | hg19_v2_chr17_-_40540377_40540481 | -0.11 | 5.5e-01 | Click! |
Activity profile of STAT1_STAT3_BCL6 motif
Sorted Z-values of STAT1_STAT3_BCL6 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_102668879 | 6.40 |
ENST00000315274.6
|
MMP1
|
matrix metallopeptidase 1 (interstitial collagenase) |
| chr12_+_93964746 | 4.89 |
ENST00000536696.2
|
SOCS2
|
suppressor of cytokine signaling 2 |
| chr5_-_146781153 | 4.46 |
ENST00000520473.1
|
DPYSL3
|
dihydropyrimidinase-like 3 |
| chr7_+_134464414 | 4.33 |
ENST00000361901.2
|
CALD1
|
caldesmon 1 |
| chr17_+_2699697 | 4.32 |
ENST00000254695.8
ENST00000366401.4 ENST00000542807.1 |
RAP1GAP2
|
RAP1 GTPase activating protein 2 |
| chr7_+_134464376 | 4.22 |
ENST00000454108.1
ENST00000361675.2 |
CALD1
|
caldesmon 1 |
| chr5_-_140013275 | 4.15 |
ENST00000512545.1
ENST00000302014.6 ENST00000401743.2 |
CD14
|
CD14 molecule |
| chr17_-_76356148 | 4.00 |
ENST00000587578.1
ENST00000330871.2 |
SOCS3
|
suppressor of cytokine signaling 3 |
| chr20_-_43280361 | 3.96 |
ENST00000372874.4
|
ADA
|
adenosine deaminase |
| chr1_-_153521597 | 3.92 |
ENST00000368712.1
|
S100A3
|
S100 calcium binding protein A3 |
| chr17_+_6347729 | 3.68 |
ENST00000572447.1
|
FAM64A
|
family with sequence similarity 64, member A |
| chr17_+_6347761 | 3.60 |
ENST00000250056.8
ENST00000571373.1 ENST00000570337.2 ENST00000572595.2 ENST00000576056.1 |
FAM64A
|
family with sequence similarity 64, member A |
| chr3_+_50649302 | 3.53 |
ENST00000446044.1
|
MAPKAPK3
|
mitogen-activated protein kinase-activated protein kinase 3 |
| chr19_+_10381769 | 3.45 |
ENST00000423829.2
ENST00000588645.1 |
ICAM1
|
intercellular adhesion molecule 1 |
| chr19_-_40324767 | 3.42 |
ENST00000601972.1
ENST00000430012.2 ENST00000323039.5 ENST00000348817.3 |
DYRK1B
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| chrX_-_48328551 | 3.41 |
ENST00000376876.3
|
SLC38A5
|
solute carrier family 38, member 5 |
| chrX_-_48328631 | 3.39 |
ENST00000429543.1
ENST00000317669.5 |
SLC38A5
|
solute carrier family 38, member 5 |
| chr5_-_39274617 | 3.18 |
ENST00000510188.1
|
FYB
|
FYN binding protein |
| chr8_-_91095099 | 3.17 |
ENST00000265431.3
|
CALB1
|
calbindin 1, 28kDa |
| chr1_-_153521714 | 3.12 |
ENST00000368713.3
|
S100A3
|
S100 calcium binding protein A3 |
| chr12_+_53443963 | 2.82 |
ENST00000546602.1
ENST00000552570.1 ENST00000549700.1 |
TENC1
|
tensin like C1 domain containing phosphatase (tensin 2) |
| chr2_-_190044480 | 2.69 |
ENST00000374866.3
|
COL5A2
|
collagen, type V, alpha 2 |
| chr4_+_69313145 | 2.57 |
ENST00000305363.4
|
TMPRSS11E
|
transmembrane protease, serine 11E |
| chr12_+_53443680 | 2.53 |
ENST00000314250.6
ENST00000451358.1 |
TENC1
|
tensin like C1 domain containing phosphatase (tensin 2) |
| chr3_-_42744312 | 2.44 |
ENST00000416756.1
ENST00000441594.1 |
HHATL
|
hedgehog acyltransferase-like |
| chr13_-_20805109 | 2.35 |
ENST00000241124.6
|
GJB6
|
gap junction protein, beta 6, 30kDa |
| chr12_+_8975061 | 2.30 |
ENST00000299698.7
|
A2ML1
|
alpha-2-macroglobulin-like 1 |
| chr10_-_90751038 | 2.27 |
ENST00000458159.1
ENST00000415557.1 ENST00000458208.1 |
ACTA2
|
actin, alpha 2, smooth muscle, aorta |
| chr10_-_33625154 | 2.23 |
ENST00000265371.4
|
NRP1
|
neuropilin 1 |
| chr16_-_74734672 | 2.17 |
ENST00000306247.7
ENST00000575686.1 |
MLKL
|
mixed lineage kinase domain-like |
| chr20_+_44637526 | 2.10 |
ENST00000372330.3
|
MMP9
|
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| chr16_-_67517716 | 2.09 |
ENST00000290953.2
|
AGRP
|
agouti related protein homolog (mouse) |
| chr19_-_40324255 | 2.07 |
ENST00000593685.1
ENST00000600611.1 |
DYRK1B
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| chr3_-_50649192 | 2.04 |
ENST00000443053.2
ENST00000348721.3 |
CISH
|
cytokine inducible SH2-containing protein |
| chr12_-_120687948 | 2.01 |
ENST00000458477.2
|
PXN
|
paxillin |
| chr12_+_56324933 | 2.00 |
ENST00000549629.1
ENST00000555218.1 |
DGKA
|
diacylglycerol kinase, alpha 80kDa |
| chr5_+_150639360 | 1.87 |
ENST00000523004.1
|
GM2A
|
GM2 ganglioside activator |
| chr6_+_35995552 | 1.82 |
ENST00000468133.1
|
MAPK14
|
mitogen-activated protein kinase 14 |
| chr14_-_81408063 | 1.77 |
ENST00000557411.1
|
CEP128
|
centrosomal protein 128kDa |
| chr18_+_34124507 | 1.66 |
ENST00000591635.1
|
FHOD3
|
formin homology 2 domain containing 3 |
| chr6_-_131321863 | 1.60 |
ENST00000528282.1
|
EPB41L2
|
erythrocyte membrane protein band 4.1-like 2 |
| chr6_+_151561085 | 1.60 |
ENST00000402676.2
|
AKAP12
|
A kinase (PRKA) anchor protein 12 |
| chr4_-_175443943 | 1.59 |
ENST00000296522.6
|
HPGD
|
hydroxyprostaglandin dehydrogenase 15-(NAD) |
| chr22_+_33197683 | 1.58 |
ENST00000266085.6
|
TIMP3
|
TIMP metallopeptidase inhibitor 3 |
| chr11_+_73003824 | 1.57 |
ENST00000538328.1
|
P2RY6
|
pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| chr3_+_136537911 | 1.57 |
ENST00000393079.3
|
SLC35G2
|
solute carrier family 35, member G2 |
| chr22_-_37640277 | 1.56 |
ENST00000401529.3
ENST00000249071.6 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr9_-_134151915 | 1.55 |
ENST00000372271.3
|
FAM78A
|
family with sequence similarity 78, member A |
| chr1_+_45212074 | 1.54 |
ENST00000372217.1
|
KIF2C
|
kinesin family member 2C |
| chr22_-_37640456 | 1.54 |
ENST00000405484.1
ENST00000441619.1 ENST00000406508.1 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr14_-_100841670 | 1.52 |
ENST00000557297.1
ENST00000555813.1 ENST00000557135.1 ENST00000556698.1 ENST00000554509.1 ENST00000555410.1 |
WARS
|
tryptophanyl-tRNA synthetase |
| chr4_-_10023095 | 1.52 |
ENST00000264784.3
|
SLC2A9
|
solute carrier family 2 (facilitated glucose transporter), member 9 |
| chr1_-_150780757 | 1.44 |
ENST00000271651.3
|
CTSK
|
cathepsin K |
| chr1_+_45212051 | 1.43 |
ENST00000372222.3
|
KIF2C
|
kinesin family member 2C |
| chr6_+_35995488 | 1.42 |
ENST00000229795.3
|
MAPK14
|
mitogen-activated protein kinase 14 |
| chr3_+_136537816 | 1.42 |
ENST00000446465.2
|
SLC35G2
|
solute carrier family 35, member G2 |
| chr7_+_76026832 | 1.41 |
ENST00000336517.4
|
ZP3
|
zona pellucida glycoprotein 3 (sperm receptor) |
| chr17_+_74372662 | 1.38 |
ENST00000591651.1
ENST00000545180.1 |
SPHK1
|
sphingosine kinase 1 |
| chr18_+_33877654 | 1.37 |
ENST00000257209.4
ENST00000445677.1 ENST00000590592.1 ENST00000359247.4 |
FHOD3
|
formin homology 2 domain containing 3 |
| chr20_+_58251716 | 1.37 |
ENST00000355648.4
|
PHACTR3
|
phosphatase and actin regulator 3 |
| chr6_+_35995531 | 1.37 |
ENST00000229794.4
|
MAPK14
|
mitogen-activated protein kinase 14 |
| chr15_+_52121822 | 1.36 |
ENST00000558455.1
ENST00000308580.7 |
TMOD3
|
tropomodulin 3 (ubiquitous) |
| chr1_-_41328018 | 1.36 |
ENST00000372638.2
|
CITED4
|
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 |
| chr5_-_39270725 | 1.35 |
ENST00000512138.1
ENST00000512982.1 ENST00000540520.1 |
FYB
|
FYN binding protein |
| chr19_-_49339732 | 1.30 |
ENST00000599157.1
|
HSD17B14
|
hydroxysteroid (17-beta) dehydrogenase 14 |
| chr12_+_56324756 | 1.30 |
ENST00000331886.5
ENST00000555090.1 |
DGKA
|
diacylglycerol kinase, alpha 80kDa |
| chr3_-_149095652 | 1.25 |
ENST00000305366.3
|
TM4SF1
|
transmembrane 4 L six family member 1 |
| chr22_+_20748456 | 1.24 |
ENST00000420626.1
ENST00000356671.5 |
ZNF74
|
zinc finger protein 74 |
| chr12_-_123187890 | 1.24 |
ENST00000328880.5
|
HCAR2
|
hydroxycarboxylic acid receptor 2 |
| chr12_-_123201337 | 1.24 |
ENST00000528880.2
|
HCAR3
|
hydroxycarboxylic acid receptor 3 |
| chr5_-_177423243 | 1.22 |
ENST00000308304.2
|
PROP1
|
PROP paired-like homeobox 1 |
| chr4_-_159094194 | 1.22 |
ENST00000592057.1
ENST00000585682.1 ENST00000393807.5 |
FAM198B
|
family with sequence similarity 198, member B |
| chr17_-_38210644 | 1.20 |
ENST00000394128.2
ENST00000394127.2 ENST00000356271.3 ENST00000535071.2 ENST00000580885.1 ENST00000543759.2 ENST00000537674.2 ENST00000580517.1 ENST00000578161.1 |
MED24
|
mediator complex subunit 24 |
| chr19_-_49339915 | 1.20 |
ENST00000263278.4
|
HSD17B14
|
hydroxysteroid (17-beta) dehydrogenase 14 |
| chr1_-_154946825 | 1.19 |
ENST00000368453.4
ENST00000368450.1 ENST00000366442.2 |
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1 |
| chr8_+_85618155 | 1.19 |
ENST00000523850.1
ENST00000521376.1 |
RALYL
|
RALY RNA binding protein-like |
| chr12_-_10007448 | 1.17 |
ENST00000538152.1
|
CLEC2B
|
C-type lectin domain family 2, member B |
| chr7_-_27135591 | 1.12 |
ENST00000343060.4
ENST00000355633.5 |
HOXA1
|
homeobox A1 |
| chr22_-_50523760 | 1.10 |
ENST00000395876.2
|
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr3_-_187455680 | 1.10 |
ENST00000438077.1
|
BCL6
|
B-cell CLL/lymphoma 6 |
| chr5_+_38845960 | 1.10 |
ENST00000502536.1
|
OSMR
|
oncostatin M receptor |
| chr19_+_35485682 | 1.08 |
ENST00000599564.1
|
GRAMD1A
|
GRAM domain containing 1A |
| chr8_+_38586068 | 1.08 |
ENST00000443286.2
ENST00000520340.1 ENST00000518415.1 |
TACC1
|
transforming, acidic coiled-coil containing protein 1 |
| chr5_+_38846101 | 1.07 |
ENST00000274276.3
|
OSMR
|
oncostatin M receptor |
| chr19_+_11200038 | 1.06 |
ENST00000558518.1
ENST00000557933.1 ENST00000455727.2 ENST00000535915.1 ENST00000545707.1 ENST00000558013.1 |
LDLR
|
low density lipoprotein receptor |
| chr19_-_11688447 | 1.06 |
ENST00000590420.1
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr5_+_148521381 | 1.04 |
ENST00000504238.1
|
ABLIM3
|
actin binding LIM protein family, member 3 |
| chr17_+_6544356 | 1.03 |
ENST00000574838.1
|
TXNDC17
|
thioredoxin domain containing 17 |
| chr17_+_6544328 | 1.03 |
ENST00000570330.1
|
TXNDC17
|
thioredoxin domain containing 17 |
| chr14_-_100841930 | 1.01 |
ENST00000555031.1
ENST00000553395.1 ENST00000553545.1 ENST00000344102.5 ENST00000556338.1 ENST00000392882.2 ENST00000553934.1 |
WARS
|
tryptophanyl-tRNA synthetase |
| chr22_+_20748405 | 1.01 |
ENST00000400451.2
ENST00000403682.3 ENST00000357502.5 |
ZNF74
|
zinc finger protein 74 |
| chr2_+_87754989 | 1.01 |
ENST00000409898.2
ENST00000419680.2 ENST00000414584.1 ENST00000455131.1 |
LINC00152
|
long intergenic non-protein coding RNA 152 |
| chr22_-_50699701 | 1.00 |
ENST00000395780.1
|
MAPK12
|
mitogen-activated protein kinase 12 |
| chr1_-_68299130 | 1.00 |
ENST00000370982.3
|
GNG12
|
guanine nucleotide binding protein (G protein), gamma 12 |
| chr19_-_58864848 | 0.99 |
ENST00000263100.3
|
A1BG
|
alpha-1-B glycoprotein |
| chr12_+_56415100 | 0.99 |
ENST00000547791.1
|
IKZF4
|
IKAROS family zinc finger 4 (Eos) |
| chr19_-_4831701 | 0.99 |
ENST00000248244.5
|
TICAM1
|
toll-like receptor adaptor molecule 1 |
| chr8_+_71485681 | 0.99 |
ENST00000391684.1
|
AC120194.1
|
AC120194.1 |
| chr12_-_52845910 | 0.98 |
ENST00000252252.3
|
KRT6B
|
keratin 6B |
| chr17_-_9694614 | 0.98 |
ENST00000330255.5
ENST00000571134.1 |
DHRS7C
|
dehydrogenase/reductase (SDR family) member 7C |
| chr2_+_87755054 | 0.98 |
ENST00000423846.1
|
LINC00152
|
long intergenic non-protein coding RNA 152 |
| chr14_-_81408031 | 0.98 |
ENST00000216517.6
|
CEP128
|
centrosomal protein 128kDa |
| chr11_+_844067 | 0.97 |
ENST00000397406.1
ENST00000409543.2 ENST00000525201.1 |
TSPAN4
|
tetraspanin 4 |
| chr11_-_62323702 | 0.97 |
ENST00000530285.1
|
AHNAK
|
AHNAK nucleoprotein |
| chr17_+_6544078 | 0.97 |
ENST00000250101.5
|
TXNDC17
|
thioredoxin domain containing 17 |
| chr17_-_76183111 | 0.96 |
ENST00000405273.1
ENST00000590862.1 ENST00000590430.1 ENST00000586613.1 |
TK1
|
thymidine kinase 1, soluble |
| chr19_-_11688500 | 0.95 |
ENST00000433365.2
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr5_+_131409476 | 0.95 |
ENST00000296871.2
|
CSF2
|
colony stimulating factor 2 (granulocyte-macrophage) |
| chr12_-_91539918 | 0.95 |
ENST00000548218.1
|
DCN
|
decorin |
| chr2_+_87754887 | 0.94 |
ENST00000409054.1
ENST00000331944.6 ENST00000409139.1 |
LINC00152
|
long intergenic non-protein coding RNA 152 |
| chr1_+_202431859 | 0.93 |
ENST00000391959.3
ENST00000367270.4 |
PPP1R12B
|
protein phosphatase 1, regulatory subunit 12B |
| chr5_+_33440802 | 0.90 |
ENST00000502553.1
ENST00000514259.1 ENST00000265112.3 |
TARS
|
threonyl-tRNA synthetase |
| chrX_+_107288197 | 0.90 |
ENST00000415430.3
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr5_+_32531893 | 0.90 |
ENST00000512913.1
|
SUB1
|
SUB1 homolog (S. cerevisiae) |
| chrX_+_107288239 | 0.90 |
ENST00000217957.5
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr11_+_844406 | 0.88 |
ENST00000397404.1
|
TSPAN4
|
tetraspanin 4 |
| chr1_+_154300217 | 0.88 |
ENST00000368489.3
|
ATP8B2
|
ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| chr17_-_41132410 | 0.88 |
ENST00000409446.3
ENST00000453594.1 ENST00000409399.1 ENST00000421990.2 |
PTGES3L
PTGES3L-AARSD1
|
prostaglandin E synthase 3 (cytosolic)-like PTGES3L-AARSD1 readthrough |
| chr15_+_63340734 | 0.88 |
ENST00000560959.1
|
TPM1
|
tropomyosin 1 (alpha) |
| chr9_+_132096166 | 0.87 |
ENST00000436710.1
|
RP11-65J3.1
|
RP11-65J3.1 |
| chr1_+_16083154 | 0.86 |
ENST00000375771.1
|
FBLIM1
|
filamin binding LIM protein 1 |
| chr15_+_63340775 | 0.85 |
ENST00000559281.1
ENST00000317516.7 |
TPM1
|
tropomyosin 1 (alpha) |
| chr10_-_121296045 | 0.85 |
ENST00000392865.1
|
RGS10
|
regulator of G-protein signaling 10 |
| chr6_-_34524049 | 0.84 |
ENST00000374037.3
|
SPDEF
|
SAM pointed domain containing ETS transcription factor |
| chr1_+_153004800 | 0.84 |
ENST00000392661.3
|
SPRR1B
|
small proline-rich protein 1B |
| chr9_-_139891165 | 0.83 |
ENST00000494426.1
|
CLIC3
|
chloride intracellular channel 3 |
| chr1_+_214163033 | 0.83 |
ENST00000607425.1
|
PROX1
|
prospero homeobox 1 |
| chr8_+_31497271 | 0.83 |
ENST00000520407.1
|
NRG1
|
neuregulin 1 |
| chr12_+_56414851 | 0.82 |
ENST00000547167.1
|
IKZF4
|
IKAROS family zinc finger 4 (Eos) |
| chr15_+_63340647 | 0.81 |
ENST00000404484.4
|
TPM1
|
tropomyosin 1 (alpha) |
| chr19_+_35168547 | 0.81 |
ENST00000502743.1
ENST00000509528.1 ENST00000506901.1 |
ZNF302
|
zinc finger protein 302 |
| chr6_-_32821599 | 0.81 |
ENST00000354258.4
|
TAP1
|
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| chr12_-_30887948 | 0.80 |
ENST00000433722.2
|
CAPRIN2
|
caprin family member 2 |
| chr14_-_30396948 | 0.80 |
ENST00000331968.5
|
PRKD1
|
protein kinase D1 |
| chr5_+_33441053 | 0.79 |
ENST00000541634.1
ENST00000455217.2 ENST00000414361.2 |
TARS
|
threonyl-tRNA synthetase |
| chr16_+_30064444 | 0.78 |
ENST00000395248.1
ENST00000566897.1 ENST00000568435.1 |
ALDOA
|
aldolase A, fructose-bisphosphate |
| chr17_-_3417062 | 0.78 |
ENST00000570318.1
ENST00000541913.1 |
SPATA22
|
spermatogenesis associated 22 |
| chr19_+_35783037 | 0.77 |
ENST00000361922.4
|
MAG
|
myelin associated glycoprotein |
| chr3_+_160117087 | 0.77 |
ENST00000357388.3
|
SMC4
|
structural maintenance of chromosomes 4 |
| chr2_-_106013400 | 0.77 |
ENST00000409807.1
|
FHL2
|
four and a half LIM domains 2 |
| chr14_-_107083690 | 0.77 |
ENST00000455737.1
ENST00000390629.2 |
IGHV4-59
|
immunoglobulin heavy variable 4-59 |
| chr6_-_33547975 | 0.77 |
ENST00000442998.2
ENST00000360661.5 |
BAK1
|
BCL2-antagonist/killer 1 |
| chr1_+_221051699 | 0.76 |
ENST00000366903.6
|
HLX
|
H2.0-like homeobox |
| chr2_+_17721230 | 0.76 |
ENST00000457525.1
|
VSNL1
|
visinin-like 1 |
| chr19_+_35783047 | 0.75 |
ENST00000595791.1
ENST00000597035.1 ENST00000537831.2 |
MAG
|
myelin associated glycoprotein |
| chr1_-_160616804 | 0.75 |
ENST00000538290.1
|
SLAMF1
|
signaling lymphocytic activation molecule family member 1 |
| chr18_+_55816546 | 0.75 |
ENST00000435432.2
ENST00000357895.5 ENST00000586263.1 |
NEDD4L
|
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| chr19_+_35783028 | 0.75 |
ENST00000600291.1
ENST00000392213.3 |
MAG
|
myelin associated glycoprotein |
| chr11_+_130318869 | 0.73 |
ENST00000299164.2
|
ADAMTS15
|
ADAM metallopeptidase with thrombospondin type 1 motif, 15 |
| chr3_+_101568349 | 0.72 |
ENST00000326151.5
ENST00000326172.5 |
NFKBIZ
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
| chr22_+_38609538 | 0.72 |
ENST00000407965.1
|
MAFF
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| chr6_-_33548006 | 0.72 |
ENST00000374467.3
|
BAK1
|
BCL2-antagonist/killer 1 |
| chr6_-_117150198 | 0.70 |
ENST00000310357.3
ENST00000368549.3 ENST00000530250.1 |
GPRC6A
|
G protein-coupled receptor, family C, group 6, member A |
| chr10_+_35484793 | 0.70 |
ENST00000488741.1
ENST00000474931.1 ENST00000468236.1 ENST00000344351.5 ENST00000490511.1 |
CREM
|
cAMP responsive element modulator |
| chr9_-_117853297 | 0.69 |
ENST00000542877.1
ENST00000537320.1 ENST00000341037.4 |
TNC
|
tenascin C |
| chr20_-_49308048 | 0.69 |
ENST00000327979.2
|
FAM65C
|
family with sequence similarity 65, member C |
| chr16_+_81040103 | 0.69 |
ENST00000305850.5
ENST00000299572.5 |
CENPN
|
centromere protein N |
| chr3_+_160117418 | 0.68 |
ENST00000465903.1
ENST00000485645.1 ENST00000360111.2 ENST00000472991.1 ENST00000467468.1 ENST00000469762.1 ENST00000489573.1 ENST00000462787.1 ENST00000490207.1 ENST00000485867.1 |
SMC4
|
structural maintenance of chromosomes 4 |
| chr19_-_15590306 | 0.68 |
ENST00000292609.4
|
PGLYRP2
|
peptidoglycan recognition protein 2 |
| chr19_+_16186903 | 0.68 |
ENST00000588507.1
|
TPM4
|
tropomyosin 4 |
| chr6_+_36646435 | 0.68 |
ENST00000244741.5
ENST00000405375.1 ENST00000373711.2 |
CDKN1A
|
cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| chr9_-_99180597 | 0.67 |
ENST00000375256.4
|
ZNF367
|
zinc finger protein 367 |
| chr15_-_56209306 | 0.66 |
ENST00000506154.1
ENST00000338963.2 ENST00000508342.1 |
NEDD4
|
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| chr1_-_241803679 | 0.66 |
ENST00000331838.5
|
OPN3
|
opsin 3 |
| chr2_-_17935059 | 0.65 |
ENST00000448223.2
ENST00000381272.4 ENST00000351948.4 |
SMC6
|
structural maintenance of chromosomes 6 |
| chrX_-_139866723 | 0.65 |
ENST00000370532.2
|
CDR1
|
cerebellar degeneration-related protein 1, 34kDa |
| chr1_+_84609944 | 0.65 |
ENST00000370685.3
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr6_+_41604747 | 0.65 |
ENST00000419164.1
ENST00000373051.2 |
MDFI
|
MyoD family inhibitor |
| chr8_+_26371763 | 0.64 |
ENST00000521913.1
|
DPYSL2
|
dihydropyrimidinase-like 2 |
| chr14_-_107283278 | 0.63 |
ENST00000390639.2
|
IGHV7-81
|
immunoglobulin heavy variable 7-81 (non-functional) |
| chr1_+_155006300 | 0.63 |
ENST00000295542.1
ENST00000392480.1 ENST00000423025.2 ENST00000368419.2 |
DCST1
|
DC-STAMP domain containing 1 |
| chr17_-_76124711 | 0.63 |
ENST00000306591.7
ENST00000590602.1 |
TMC6
|
transmembrane channel-like 6 |
| chr9_-_117880477 | 0.62 |
ENST00000534839.1
ENST00000340094.3 ENST00000535648.1 ENST00000346706.3 ENST00000345230.3 ENST00000350763.4 |
TNC
|
tenascin C |
| chr11_+_57365150 | 0.62 |
ENST00000457869.1
ENST00000340687.6 ENST00000378323.4 ENST00000378324.2 ENST00000403558.1 |
SERPING1
|
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| chr7_-_107443652 | 0.62 |
ENST00000340010.5
ENST00000422236.2 ENST00000453332.1 |
SLC26A3
|
solute carrier family 26 (anion exchanger), member 3 |
| chr4_+_158141899 | 0.62 |
ENST00000264426.9
ENST00000506284.1 |
GRIA2
|
glutamate receptor, ionotropic, AMPA 2 |
| chr1_+_165864800 | 0.61 |
ENST00000469256.2
|
UCK2
|
uridine-cytidine kinase 2 |
| chr1_+_22979474 | 0.61 |
ENST00000509305.1
|
C1QB
|
complement component 1, q subcomponent, B chain |
| chr19_-_41220957 | 0.61 |
ENST00000596357.1
ENST00000243583.6 ENST00000600080.1 ENST00000595254.1 ENST00000601967.1 |
ADCK4
|
aarF domain containing kinase 4 |
| chr3_+_187871060 | 0.61 |
ENST00000448637.1
|
LPP
|
LIM domain containing preferred translocation partner in lipoma |
| chr22_-_36357671 | 0.61 |
ENST00000408983.2
|
RBFOX2
|
RNA binding protein, fox-1 homolog (C. elegans) 2 |
| chr22_-_28315115 | 0.60 |
ENST00000455418.3
ENST00000436663.1 ENST00000320996.10 ENST00000335272.5 |
PITPNB
|
phosphatidylinositol transfer protein, beta |
| chr5_-_114961673 | 0.60 |
ENST00000333314.3
|
TMED7-TICAM2
|
TMED7-TICAM2 readthrough |
| chr2_-_136633940 | 0.59 |
ENST00000264156.2
|
MCM6
|
minichromosome maintenance complex component 6 |
| chr6_-_43484621 | 0.59 |
ENST00000506469.1
ENST00000503972.1 |
YIPF3
|
Yip1 domain family, member 3 |
| chr5_+_145718587 | 0.59 |
ENST00000230732.4
|
POU4F3
|
POU class 4 homeobox 3 |
| chr1_-_156571254 | 0.58 |
ENST00000438976.2
ENST00000334588.7 ENST00000368232.4 ENST00000415314.2 |
GPATCH4
|
G patch domain containing 4 |
| chr20_+_42984330 | 0.57 |
ENST00000316673.4
ENST00000609795.1 ENST00000457232.1 ENST00000609262.1 |
HNF4A
|
hepatocyte nuclear factor 4, alpha |
| chr19_+_49535169 | 0.57 |
ENST00000474913.1
ENST00000359342.6 |
CGB2
|
chorionic gonadotropin, beta polypeptide 2 |
| chr1_-_241803649 | 0.57 |
ENST00000366554.2
|
OPN3
|
opsin 3 |
| chr5_-_132112907 | 0.57 |
ENST00000458488.2
|
SEPT8
|
septin 8 |
| chr16_-_57836321 | 0.57 |
ENST00000569112.1
ENST00000562311.1 ENST00000445690.2 ENST00000379655.4 |
KIFC3
|
kinesin family member C3 |
| chr15_+_75182346 | 0.57 |
ENST00000569931.1
ENST00000352410.4 ENST00000566377.1 ENST00000569233.1 ENST00000567132.1 ENST00000564633.1 ENST00000568907.1 ENST00000563422.1 ENST00000564003.1 ENST00000562800.1 ENST00000563786.1 ENST00000535694.1 ENST00000323744.6 ENST00000568828.1 ENST00000562606.1 ENST00000565576.1 ENST00000567570.1 |
MPI
|
mannose phosphate isomerase |
| chr1_+_165864821 | 0.57 |
ENST00000470820.1
|
UCK2
|
uridine-cytidine kinase 2 |
| chr11_-_2162468 | 0.57 |
ENST00000434045.2
|
IGF2
|
insulin-like growth factor 2 (somatomedin A) |
| chr9_+_18474204 | 0.56 |
ENST00000276935.6
|
ADAMTSL1
|
ADAMTS-like 1 |
| chr17_-_46691990 | 0.56 |
ENST00000576562.1
|
HOXB8
|
homeobox B8 |
| chr18_-_31802056 | 0.56 |
ENST00000538587.1
|
NOL4
|
nucleolar protein 4 |
| chr7_+_35756092 | 0.56 |
ENST00000458087.3
|
AC018647.3
|
AC018647.3 |
| chr19_+_11546440 | 0.55 |
ENST00000589126.1
ENST00000588269.1 ENST00000587509.1 ENST00000592741.1 ENST00000593101.1 ENST00000587327.1 |
PRKCSH
|
protein kinase C substrate 80K-H |
Network of associatons between targets according to the STRING database.
First level regulatory network of STAT1_STAT3_BCL6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 4.0 | GO:0006154 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 1.0 | 4.1 | GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
| 1.0 | 4.0 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.9 | 4.6 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.9 | 2.7 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.9 | 3.4 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.8 | 2.4 | GO:0006500 | N-terminal protein palmitoylation(GO:0006500) |
| 0.5 | 2.5 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.5 | 1.5 | GO:0002352 | B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 0.5 | 6.8 | GO:0015816 | glycine transport(GO:0015816) |
| 0.5 | 1.4 | GO:2000196 | positive regulation of female gonad development(GO:2000196) |
| 0.5 | 1.4 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.4 | 2.2 | GO:1904835 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.4 | 1.7 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
| 0.4 | 2.0 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.4 | 1.6 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.4 | 2.3 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.4 | 1.1 | GO:0032764 | negative regulation of mast cell cytokine production(GO:0032764) |
| 0.4 | 2.2 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.4 | 3.2 | GO:0035502 | metanephric part of ureteric bud development(GO:0035502) |
| 0.3 | 2.5 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.3 | 0.9 | GO:1902910 | regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910) |
| 0.3 | 0.3 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.3 | 4.5 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.3 | 3.0 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.3 | 1.2 | GO:0009224 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 0.3 | 3.1 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.3 | 0.8 | GO:0061114 | hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 0.3 | 3.5 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.3 | 1.3 | GO:1903978 | regulation of microglial cell activation(GO:1903978) |
| 0.3 | 2.1 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.3 | 1.3 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
| 0.3 | 0.8 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.3 | 0.8 | GO:0002277 | myeloid dendritic cell activation involved in immune response(GO:0002277) |
| 0.2 | 1.2 | GO:0048850 | hypophysis morphogenesis(GO:0048850) |
| 0.2 | 0.2 | GO:1990641 | response to iron ion starvation(GO:1990641) |
| 0.2 | 1.0 | GO:0046125 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 0.2 | 1.2 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
| 0.2 | 4.9 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.2 | 0.7 | GO:0032826 | natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) |
| 0.2 | 0.9 | GO:0072255 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.2 | 2.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.2 | 1.9 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.2 | 1.2 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.2 | 2.3 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
| 0.2 | 0.8 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 0.2 | 0.8 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.2 | 0.8 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
| 0.2 | 0.8 | GO:0000711 | meiotic DNA repair synthesis(GO:0000711) |
| 0.2 | 0.9 | GO:0045337 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 0.2 | 1.5 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.2 | 2.9 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.2 | 1.4 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.2 | 0.7 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 0.2 | 1.6 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.2 | 0.7 | GO:0001189 | RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189) |
| 0.2 | 0.8 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.2 | 0.5 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 0.2 | 0.5 | GO:0043318 | negative regulation of dendritic cell antigen processing and presentation(GO:0002605) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318) |
| 0.2 | 0.8 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 2.5 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.1 | 0.4 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.1 | 1.2 | GO:0034128 | negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) |
| 0.1 | 0.4 | GO:1902024 | histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024) |
| 0.1 | 1.3 | GO:1903027 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027) |
| 0.1 | 0.8 | GO:0060480 | lung goblet cell differentiation(GO:0060480) |
| 0.1 | 0.4 | GO:0031247 | actin rod assembly(GO:0031247) |
| 0.1 | 1.4 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.1 | 0.7 | GO:0060574 | intestinal epithelial cell maturation(GO:0060574) |
| 0.1 | 0.4 | GO:0098968 | neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968) |
| 0.1 | 1.8 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.1 | 1.0 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 0.3 | GO:0050720 | interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.1 | 1.0 | GO:2000852 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 0.1 | 1.1 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 0.1 | 0.5 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.1 | 0.4 | GO:0060621 | negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910) |
| 0.1 | 1.6 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.1 | 0.5 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.1 | 5.2 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 0.4 | GO:0016094 | polyprenol biosynthetic process(GO:0016094) |
| 0.1 | 0.5 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.1 | 0.5 | GO:0007402 | ganglion mother cell fate determination(GO:0007402) |
| 0.1 | 0.8 | GO:0021840 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
| 0.1 | 0.9 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.1 | 0.4 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.1 | 1.1 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 0.6 | GO:0045590 | negative regulation of regulatory T cell differentiation(GO:0045590) |
| 0.1 | 0.3 | GO:0002728 | negative regulation of natural killer cell cytokine production(GO:0002728) |
| 0.1 | 0.4 | GO:0009644 | response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) |
| 0.1 | 0.1 | GO:0014839 | myoblast migration involved in skeletal muscle regeneration(GO:0014839) |
| 0.1 | 0.3 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.1 | 0.3 | GO:0051685 | maintenance of ER location(GO:0051685) |
| 0.1 | 1.6 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.1 | 0.4 | GO:2000110 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.1 | 1.8 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.1 | 5.3 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.1 | 3.8 | GO:0032461 | positive regulation of protein oligomerization(GO:0032461) |
| 0.1 | 3.9 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 0.6 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.1 | 1.3 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 2.0 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.1 | 0.3 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
| 0.1 | 0.6 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.1 | 0.6 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.1 | 0.3 | GO:1901253 | negative regulation of intracellular transport of viral material(GO:1901253) |
| 0.1 | 0.3 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.1 | 1.5 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.1 | 0.3 | GO:0044211 | CTP salvage(GO:0044211) |
| 0.1 | 1.1 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.1 | 0.6 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.1 | 0.4 | GO:0030070 | insulin processing(GO:0030070) |
| 0.1 | 0.3 | GO:1904647 | response to rotenone(GO:1904647) |
| 0.1 | 1.1 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.1 | 0.6 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.1 | 0.3 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651) |
| 0.1 | 0.4 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.1 | 1.3 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.1 | 0.4 | GO:0009253 | peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) |
| 0.1 | 0.1 | GO:0006844 | acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616) |
| 0.1 | 0.7 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.1 | 0.6 | GO:0045916 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
| 0.1 | 0.3 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.1 | 0.3 | GO:0072619 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.1 | 0.5 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.1 | 0.6 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.3 | GO:0071469 | detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469) |
| 0.1 | 0.3 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.1 | 0.9 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.1 | 0.4 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.1 | 0.4 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.1 | 0.8 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.1 | 0.2 | GO:0050883 | negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.1 | 0.2 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.1 | 0.6 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.4 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.1 | 0.2 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.1 | 0.4 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.1 | 0.2 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
| 0.1 | 0.3 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.1 | 0.3 | GO:0019075 | virus maturation(GO:0019075) |
| 0.1 | 0.3 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.1 | 0.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.1 | 0.6 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 0.2 | GO:0046013 | T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.1 | 0.5 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 0.5 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 0.6 | GO:0099612 | protein localization to axon(GO:0099612) |
| 0.0 | 0.3 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.0 | 0.0 | GO:0032242 | regulation of nucleoside transport(GO:0032242) |
| 0.0 | 0.2 | GO:0001757 | somite specification(GO:0001757) |
| 0.0 | 0.3 | GO:0097647 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.0 | 0.3 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.0 | 0.2 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.0 | 0.8 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.0 | 1.1 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 2.3 | GO:0051602 | response to electrical stimulus(GO:0051602) |
| 0.0 | 0.1 | GO:0090156 | cellular sphingolipid homeostasis(GO:0090156) |
| 0.0 | 0.2 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.0 | 0.5 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.4 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.4 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.0 | 0.4 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.0 | 0.8 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.0 | 1.4 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.0 | 0.6 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.0 | 0.2 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
| 0.0 | 0.3 | GO:1901475 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.0 | 0.3 | GO:0043380 | regulation of memory T cell differentiation(GO:0043380) |
| 0.0 | 0.2 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 0.0 | 0.7 | GO:0051775 | response to redox state(GO:0051775) |
| 0.0 | 0.2 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.0 | 0.2 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.0 | 0.8 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.0 | 1.2 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.0 | 0.5 | GO:0061303 | cornea development in camera-type eye(GO:0061303) |
| 0.0 | 0.2 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.0 | 0.1 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.0 | 0.4 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.0 | 0.2 | GO:0001878 | response to yeast(GO:0001878) |
| 0.0 | 0.2 | GO:0015862 | uridine transport(GO:0015862) |
| 0.0 | 0.1 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.0 | 0.8 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.3 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.0 | 0.2 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.0 | 0.3 | GO:0044857 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) |
| 0.0 | 0.8 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.0 | 0.1 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
| 0.0 | 1.6 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.1 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) neurotransmitter receptor internalization(GO:0099590) |
| 0.0 | 0.8 | GO:0015813 | L-glutamate transport(GO:0015813) |
| 0.0 | 0.4 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.0 | 0.6 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 0.5 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.0 | 0.5 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 0.0 | 0.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.4 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.0 | 1.0 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.0 | 0.2 | GO:0038060 | nitric oxide-cGMP-mediated signaling pathway(GO:0038060) |
| 0.0 | 0.6 | GO:0030728 | ovulation(GO:0030728) |
| 0.0 | 0.5 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 0.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.0 | 0.5 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.0 | 0.6 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.1 | GO:0046968 | peptide antigen transport(GO:0046968) |
| 0.0 | 0.5 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.0 | 0.2 | GO:0071964 | unidimensional cell growth(GO:0009826) regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 0.0 | 0.1 | GO:0010166 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.0 | 0.7 | GO:0051984 | positive regulation of chromosome segregation(GO:0051984) |
| 0.0 | 0.3 | GO:0006469 | negative regulation of protein kinase activity(GO:0006469) |
| 0.0 | 0.4 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.0 | 0.2 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.0 | 2.1 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.7 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.0 | 0.8 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.0 | 0.8 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.0 | 1.0 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.0 | GO:0002874 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) |
| 0.0 | 0.2 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
| 0.0 | 0.0 | GO:0060545 | positive regulation of necroptotic process(GO:0060545) |
| 0.0 | 0.1 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.0 | 0.3 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.0 | 0.7 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.2 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.0 | 0.8 | GO:0010880 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) |
| 0.0 | 0.1 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.0 | 0.3 | GO:0045216 | cell-cell junction organization(GO:0045216) |
| 0.0 | 0.3 | GO:0034116 | positive regulation of heterotypic cell-cell adhesion(GO:0034116) |
| 0.0 | 3.4 | GO:0008361 | regulation of cell size(GO:0008361) |
| 0.0 | 0.9 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.5 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 7.1 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.0 | 0.2 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
| 0.0 | 0.1 | GO:0001828 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.0 | 2.2 | GO:0098869 | cellular oxidant detoxification(GO:0098869) |
| 0.0 | 0.8 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 1.0 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 0.2 | GO:0046051 | UTP metabolic process(GO:0046051) |
| 0.0 | 0.3 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 0.7 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 0.0 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.0 | 0.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.2 | GO:0007369 | gastrulation(GO:0007369) |
| 0.0 | 0.0 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.0 | 0.2 | GO:0022010 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 0.0 | 0.7 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.3 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.2 | GO:0007625 | grooming behavior(GO:0007625) |
| 0.0 | 0.2 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.0 | 0.0 | GO:1902019 | regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 0.0 | 0.3 | GO:0048535 | lymph node development(GO:0048535) |
| 0.0 | 0.0 | GO:0032747 | interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747) |
| 0.0 | 1.0 | GO:0071806 | protein transmembrane transport(GO:0071806) |
| 0.0 | 1.4 | GO:0060079 | excitatory postsynaptic potential(GO:0060079) |
| 0.0 | 0.0 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
| 0.0 | 0.9 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.1 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.6 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 0.3 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.0 | 0.0 | GO:0060620 | regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909) |
| 0.0 | 0.1 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 0.7 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 1.2 | GO:0038096 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
| 0.0 | 0.2 | GO:0043627 | response to estrogen(GO:0043627) |
| 0.0 | 0.3 | GO:0042438 | melanin biosynthetic process(GO:0042438) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.7 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.8 | 4.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.8 | 2.3 | GO:0097453 | mesaxon(GO:0097453) ensheathing process(GO:1990015) |
| 0.7 | 2.2 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
| 0.6 | 8.4 | GO:0030478 | actin cap(GO:0030478) |
| 0.5 | 1.9 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.4 | 2.3 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.4 | 1.9 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 0.4 | 1.1 | GO:1990666 | PCSK9-LDLR complex(GO:1990666) |
| 0.3 | 1.6 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 0.2 | 2.2 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.2 | 0.7 | GO:0005668 | RNA polymerase transcription factor SL1 complex(GO:0005668) |
| 0.2 | 1.1 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 0.2 | 0.7 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.2 | 1.6 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.2 | 1.2 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.2 | 3.5 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.2 | 0.5 | GO:0030849 | Y chromosome(GO:0000806) autosome(GO:0030849) |
| 0.1 | 0.4 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.1 | 1.5 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 0.7 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.1 | 0.4 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.1 | 4.4 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 0.8 | GO:0042825 | TAP complex(GO:0042825) |
| 0.1 | 0.5 | GO:0071062 | rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.1 | 1.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 1.5 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 3.7 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 0.5 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.1 | 1.6 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 0.3 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.1 | 0.3 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.1 | 1.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 0.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.1 | 2.1 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 2.0 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.4 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.1 | 0.4 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.1 | 3.8 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 0.3 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.1 | 0.9 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 0.1 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.1 | 0.2 | GO:0016938 | kinesin I complex(GO:0016938) |
| 0.1 | 0.4 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.1 | 2.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 0.5 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 0.2 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.1 | 3.3 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.4 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 1.1 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 4.7 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.1 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.0 | 0.4 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 0.0 | 0.3 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.0 | 0.3 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.6 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.8 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.0 | 0.6 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.3 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.0 | 0.6 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 7.6 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.2 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.8 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 0.1 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.0 | 3.4 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 0.3 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.0 | 0.2 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 2.3 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.8 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.3 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 1.0 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.1 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.0 | 0.5 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.0 | 0.3 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 10.0 | GO:0015629 | actin cytoskeleton(GO:0015629) |
| 0.0 | 0.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.2 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.4 | GO:0043186 | cytoplasmic exosome (RNase complex)(GO:0000177) P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.0 | 0.6 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 1.2 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 1.4 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 0.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 0.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.3 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 0.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 1.0 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.3 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 0.3 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 1.3 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.3 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 1.4 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 0.4 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.4 | GO:0031091 | platelet alpha granule(GO:0031091) |
| 0.0 | 0.8 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.2 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 0.6 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 0.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.0 | 0.8 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 0.1 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 0.6 | GO:0098636 | protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.6 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 0.3 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 0.1 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 4.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.3 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 4.8 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.8 | 4.9 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.6 | 3.2 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.6 | 6.8 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.5 | 2.5 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.4 | 2.2 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.4 | 1.7 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
| 0.4 | 4.6 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.4 | 2.5 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.4 | 1.6 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 0.4 | 4.5 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 1.0 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 0.3 | 9.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.3 | 3.0 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.3 | 2.2 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.3 | 0.8 | GO:0003881 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881) |
| 0.3 | 1.6 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.2 | 4.0 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.2 | 0.7 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.2 | 3.0 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.2 | 0.6 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.2 | 1.3 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.2 | 1.9 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.2 | 2.7 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.2 | 0.9 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.2 | 0.5 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.2 | 3.5 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.2 | 0.5 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.2 | 3.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.2 | 1.2 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.2 | 1.6 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.2 | 1.1 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.1 | 1.0 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
| 0.1 | 2.0 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.1 | 1.4 | GO:0032190 | manganese ion transmembrane transporter activity(GO:0005384) acrosin binding(GO:0032190) |
| 0.1 | 1.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 1.3 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.1 | 1.0 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.1 | 0.4 | GO:0002094 | polyprenyltransferase activity(GO:0002094) |
| 0.1 | 1.0 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.1 | 0.3 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 0.1 | 0.8 | GO:0046979 | TAP2 binding(GO:0046979) |
| 0.1 | 0.5 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.1 | 0.4 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
| 0.1 | 0.4 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.1 | 0.3 | GO:0008457 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 0.1 | 0.7 | GO:0008481 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.1 | 1.5 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.1 | 0.4 | GO:0022858 | L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 0.1 | 0.3 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
| 0.1 | 1.5 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.1 | 0.3 | GO:0032093 | SAM domain binding(GO:0032093) |
| 0.1 | 1.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 0.4 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.1 | 0.8 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 1.3 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.1 | 1.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 0.3 | GO:0098782 | mechanically-gated potassium channel activity(GO:0098782) |
| 0.1 | 0.3 | GO:0030627 | pre-mRNA 5'-splice site binding(GO:0030627) |
| 0.1 | 0.4 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.1 | 1.0 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 0.8 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.1 | 4.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 2.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 2.0 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 5.5 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.1 | 0.3 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.1 | 0.9 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 0.4 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.1 | 1.1 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.1 | 0.8 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.1 | 0.4 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.1 | 1.5 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 1.0 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.1 | 0.4 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.1 | 9.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 0.8 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.1 | 0.4 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.1 | 1.0 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.1 | 0.4 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.1 | 0.4 | GO:0030109 | HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) |
| 0.1 | 1.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 2.1 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 0.4 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.1 | 1.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 1.1 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.1 | 0.3 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.1 | 0.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.1 | 0.2 | GO:0070538 | oleic acid binding(GO:0070538) |
| 0.1 | 0.6 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.1 | 0.2 | GO:0005275 | amine transmembrane transporter activity(GO:0005275) |
| 0.0 | 0.8 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.7 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.0 | 0.6 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.2 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.0 | 0.5 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.6 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.9 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 1.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.7 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.3 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.0 | 0.3 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 0.0 | 0.3 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.0 | 0.5 | GO:0019864 | IgG binding(GO:0019864) |
| 0.0 | 1.0 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.0 | 0.3 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.0 | 0.8 | GO:0001164 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.0 | 3.4 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 1.0 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.2 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.0 | 0.3 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 0.1 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 0.0 | 0.2 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.0 | 0.3 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.3 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.0 | 0.5 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.0 | 0.3 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.0 | 1.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.1 | GO:0004362 | glutathione-disulfide reductase activity(GO:0004362) |
| 0.0 | 0.2 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 0.8 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.2 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.0 | 3.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.9 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.2 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.0 | 0.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 2.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.6 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 0.5 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.0 | 0.1 | GO:0015227 | acyl carnitine transmembrane transporter activity(GO:0015227) |
| 0.0 | 3.1 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.4 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.0 | 0.3 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 2.7 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 0.3 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 3.1 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 0.1 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.0 | 0.7 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.2 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.0 | 0.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.1 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 0.1 | GO:0019210 | kinase inhibitor activity(GO:0019210) |
| 0.0 | 0.3 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.0 | 0.1 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.0 | 0.3 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.6 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.1 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.0 | 0.1 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.1 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.0 | 0.6 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 0.1 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.4 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.2 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.0 | 1.1 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.1 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.0 | 0.6 | GO:0008134 | transcription factor binding(GO:0008134) |
| 0.0 | 0.4 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 1.4 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 4.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.3 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 12.1 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.2 | 2.0 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.2 | 8.1 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 5.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 3.1 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 8.8 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 4.3 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 2.3 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.1 | 4.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 1.0 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.1 | 5.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 1.5 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 1.0 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 2.9 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 4.5 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 5.0 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 0.8 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.1 | 0.4 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 1.2 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 1.0 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.0 | 0.6 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 3.1 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.7 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 1.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 1.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.7 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.0 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.8 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.7 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 1.1 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.5 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 2.3 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 0.8 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.7 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 1.3 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 0.4 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.0 | 1.3 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.3 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.5 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.7 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.8 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 0.4 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 3.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.3 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 1.1 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 1.5 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.2 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.3 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.3 | 9.1 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.3 | 7.3 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 8.8 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.2 | 14.2 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 9.5 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.2 | 2.0 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 4.5 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.1 | 6.8 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 3.1 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.1 | 1.5 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.1 | 4.1 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 1.4 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 5.1 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 3.5 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 2.0 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 1.3 | REACTOME OPSINS | Genes involved in Opsins |
| 0.1 | 3.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 2.3 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 3.3 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 1.6 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 1.1 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 1.5 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 1.0 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.1 | 1.1 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.1 | 5.2 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 2.1 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.1 | 2.1 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 1.7 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 1.0 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.1 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 2.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.8 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 1.2 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 0.5 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 0.4 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 1.0 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 0.1 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 0.9 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 1.2 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 1.8 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.6 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.7 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.6 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.5 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.9 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 0.4 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.8 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.9 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.5 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.4 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.0 | 2.0 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 1.2 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 0.3 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.4 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 0.6 | REACTOME CTLA4 INHIBITORY SIGNALING | Genes involved in CTLA4 inhibitory signaling |
| 0.0 | 0.7 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.6 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.0 | 0.3 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.0 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.0 | 0.6 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 1.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.7 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 2.2 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.2 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.0 | 0.1 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.0 | 1.4 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 3.6 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.2 | REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.0 | 0.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.4 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 1.7 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 1.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.3 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.0 | 0.7 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.3 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 0.2 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 0.2 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.0 | 0.2 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.0 | 0.2 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |