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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for STAT4

Z-value: 0.68

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Transcription factors associated with STAT4

Gene Symbol Gene ID Gene Info
STAT4
ENSG00000138378.13 signal transducer and activator of transcription 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT4hg19_v2_chr2_-_192016316_192016325-0.532.6e-03Click!

Activity profile of STAT4 motif

Sorted Z-values of STAT4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_161337662 4.21 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr6_+_32407619 4.15 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr14_-_21270561 3.02 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr1_-_109655377 2.92 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr1_-_109655355 2.91 ENST00000369945.3
C1orf194
chromosome 1 open reading frame 194
chr6_+_32821924 1.90 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr5_+_140227048 1.83 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr5_-_121413974 1.76 ENST00000231004.4
LOX
lysyl oxidase
chr5_+_140261703 1.74 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr16_+_19467772 1.70 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr3_-_148939835 1.65 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr16_+_58283814 1.44 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr5_-_16509101 1.32 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr12_+_113587558 1.22 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr19_+_35168567 1.07 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr19_+_35225060 1.04 ENST00000599244.1
ENST00000392232.3
ZNF181
zinc finger protein 181
chr5_-_111092873 1.02 ENST00000509025.1
ENST00000515855.1
NREP
neuronal regeneration related protein
chr6_-_110011704 1.01 ENST00000448084.2
AK9
adenylate kinase 9
chr10_-_116444371 0.98 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr6_+_32811861 0.97 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr7_+_117120017 0.97 ENST00000003084.6
ENST00000454343.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr5_-_111093406 0.95 ENST00000379671.3
NREP
neuronal regeneration related protein
chr3_-_114866084 0.94 ENST00000357258.3
ZBTB20
zinc finger and BTB domain containing 20
chr6_-_110011718 0.94 ENST00000532976.1
AK9
adenylate kinase 9
chr19_+_35168633 0.93 ENST00000505365.2
ZNF302
zinc finger protein 302
chr5_-_111092930 0.91 ENST00000257435.7
NREP
neuronal regeneration related protein
chr22_-_38349552 0.86 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
C22orf23
chromosome 22 open reading frame 23
chr5_-_111093167 0.86 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr12_-_15082050 0.85 ENST00000540097.1
ERP27
endoplasmic reticulum protein 27
chrX_+_144908928 0.78 ENST00000408967.2
TMEM257
transmembrane protein 257
chr5_-_111093340 0.70 ENST00000508870.1
NREP
neuronal regeneration related protein
chr19_-_50529193 0.70 ENST00000596445.1
ENST00000599538.1
VRK3
vaccinia related kinase 3
chr20_-_21494654 0.69 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr11_+_6411670 0.69 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr11_-_118436707 0.68 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr19_+_44669280 0.68 ENST00000590089.1
ENST00000454662.2
ZNF226
zinc finger protein 226
chr11_+_117070904 0.68 ENST00000529792.1
TAGLN
transgelin
chr16_-_67260691 0.65 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr5_-_111093081 0.65 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr3_+_171561127 0.62 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr9_+_100069933 0.60 ENST00000529487.1
CCDC180
coiled-coil domain containing 180
chr14_-_21490653 0.57 ENST00000449431.2
NDRG2
NDRG family member 2
chr14_-_21490417 0.56 ENST00000556366.1
NDRG2
NDRG family member 2
chr16_+_78056412 0.56 ENST00000299642.4
ENST00000575655.1
CLEC3A
C-type lectin domain family 3, member A
chrX_-_137793826 0.54 ENST00000315930.6
FGF13
fibroblast growth factor 13
chr14_-_21490958 0.53 ENST00000554104.1
NDRG2
NDRG family member 2
chr1_+_202431859 0.53 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr11_+_123986069 0.53 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr12_+_58138800 0.51 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
TSPAN31
tetraspanin 31
chr14_-_21490590 0.50 ENST00000557633.1
NDRG2
NDRG family member 2
chr7_-_92855762 0.49 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr5_+_73109339 0.49 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr12_+_58138664 0.48 ENST00000257910.3
TSPAN31
tetraspanin 31
chr10_-_104179682 0.46 ENST00000406432.1
PSD
pleckstrin and Sec7 domain containing
chr10_+_102790980 0.46 ENST00000393459.1
ENST00000224807.5
SFXN3
sideroflexin 3
chr18_+_6729698 0.45 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr13_+_97928395 0.44 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr21_+_38593701 0.43 ENST00000440629.1
AP001432.14
AP001432.14
chr6_-_32811771 0.42 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr1_-_120935894 0.42 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr19_-_51875894 0.42 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr5_-_114632307 0.40 ENST00000506442.1
ENST00000379611.5
CCDC112
coiled-coil domain containing 112
chr9_-_116163400 0.37 ENST00000277315.5
ENST00000448137.1
ENST00000409155.3
ALAD
aminolevulinate dehydratase
chr2_-_160473114 0.36 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr3_-_156534754 0.36 ENST00000472943.1
ENST00000473352.1
LINC00886
long intergenic non-protein coding RNA 886
chr2_-_79386786 0.36 ENST00000393878.1
ENST00000305165.2
ENST00000409839.3
REG3A
regenerating islet-derived 3 alpha
chr22_-_31536480 0.35 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chrX_-_46187069 0.35 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr19_+_44331493 0.34 ENST00000588797.1
ZNF283
zinc finger protein 283
chr2_-_160472952 0.34 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr1_+_9299895 0.33 ENST00000602477.1
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr1_-_144994909 0.33 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chrX_+_135570046 0.32 ENST00000370648.3
BRS3
bombesin-like receptor 3
chr16_+_4674814 0.32 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr19_+_39881951 0.31 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr7_+_117120106 0.31 ENST00000426809.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr2_-_29297127 0.30 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr19_+_10197463 0.29 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr4_-_187476721 0.29 ENST00000307161.5
MTNR1A
melatonin receptor 1A
chr3_-_183735651 0.29 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr19_+_44331444 0.29 ENST00000324461.7
ZNF283
zinc finger protein 283
chr11_+_118175596 0.28 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr13_-_41240717 0.27 ENST00000379561.5
FOXO1
forkhead box O1
chr16_+_4674787 0.26 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr3_-_187455680 0.26 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr16_+_67261008 0.25 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
TMEM208
transmembrane protein 208
chr14_-_20881579 0.25 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
TEP1
telomerase-associated protein 1
chr16_+_66600294 0.25 ENST00000535705.1
ENST00000332695.7
ENST00000336328.6
ENST00000528324.1
ENST00000531885.1
ENST00000529506.1
ENST00000457188.2
ENST00000533666.1
ENST00000533953.1
ENST00000379500.2
ENST00000328020.6
CMTM1
CKLF-like MARVEL transmembrane domain containing 1
chr17_-_77924627 0.25 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr6_+_46761118 0.24 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr11_-_10590238 0.23 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr8_-_27468842 0.23 ENST00000523500.1
CLU
clusterin
chr6_+_52051171 0.22 ENST00000340057.1
IL17A
interleukin 17A
chr4_+_130017268 0.22 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr6_-_49712123 0.22 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr19_+_50528971 0.22 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
ZNF473
zinc finger protein 473
chr11_+_118175132 0.21 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chrX_-_70474910 0.21 ENST00000373988.1
ENST00000373998.1
ZMYM3
zinc finger, MYM-type 3
chr15_-_52944231 0.20 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr1_+_40997233 0.20 ENST00000372699.3
ENST00000372697.3
ENST00000372696.3
ZNF684
zinc finger protein 684
chr15_+_65843130 0.20 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr6_-_136610911 0.19 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCLAF1
BCL2-associated transcription factor 1
chr15_+_45021183 0.19 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr16_-_67260901 0.19 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29
AC040160.1
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr13_+_100153665 0.19 ENST00000376387.4
TM9SF2
transmembrane 9 superfamily member 2
chr13_-_45915221 0.19 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1
tumor protein, translationally-controlled 1
chr1_-_231005310 0.19 ENST00000470540.1
C1orf198
chromosome 1 open reading frame 198
chr22_+_24551765 0.19 ENST00000337989.7
CABIN1
calcineurin binding protein 1
chrX_-_65253506 0.19 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr4_-_140005443 0.19 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chrX_-_154563889 0.18 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr9_-_116837249 0.18 ENST00000466610.2
AMBP
alpha-1-microglobulin/bikunin precursor
chr12_-_49245936 0.18 ENST00000308025.3
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr1_+_161551101 0.18 ENST00000367962.4
ENST00000367960.5
ENST00000403078.3
ENST00000428605.2
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr11_-_119999539 0.18 ENST00000541857.1
TRIM29
tripartite motif containing 29
chr6_+_134210243 0.18 ENST00000367882.4
TCF21
transcription factor 21
chr20_+_5731083 0.18 ENST00000445603.1
ENST00000442185.1
C20orf196
chromosome 20 open reading frame 196
chr12_-_55367361 0.17 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1
thymocyte expressed, positive selection associated 1
chr14_+_65381079 0.17 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
CHURC1
FNTB
CHURC1-FNTB
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr14_+_56127989 0.17 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr19_+_50529212 0.16 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
ZNF473
zinc finger protein 473
chr12_-_11175219 0.16 ENST00000390673.2
TAS2R19
taste receptor, type 2, member 19
chr3_-_52864680 0.16 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr11_-_119999611 0.16 ENST00000529044.1
TRIM29
tripartite motif containing 29
chr5_+_140753444 0.16 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr2_-_202563414 0.16 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr3_+_122296465 0.15 ENST00000483793.1
PARP15
poly (ADP-ribose) polymerase family, member 15
chr17_+_41132564 0.15 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr9_+_72658490 0.15 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr17_-_58603568 0.14 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr5_+_40909354 0.14 ENST00000313164.9
C7
complement component 7
chr19_+_37709076 0.14 ENST00000590503.1
ENST00000589413.1
ZNF383
zinc finger protein 383
chr20_-_18774614 0.14 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr2_+_234826016 0.14 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr15_+_57998821 0.14 ENST00000299638.3
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr14_-_25103472 0.13 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr3_+_45429998 0.13 ENST00000265537.3
ENST00000415258.1
ENST00000431023.1
ENST00000414984.1
LARS2
leucyl-tRNA synthetase 2, mitochondrial
chr6_-_25874440 0.13 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr2_-_202562774 0.13 ENST00000396886.3
ENST00000409143.1
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_-_162346657 0.13 ENST00000367935.5
C1orf111
chromosome 1 open reading frame 111
chr1_+_149754227 0.13 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr16_-_46782221 0.12 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr15_+_57998923 0.11 ENST00000380557.4
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr1_-_8000872 0.11 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr12_+_20848282 0.11 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr20_+_8112824 0.10 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr2_-_177502254 0.10 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr17_-_34207295 0.10 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr10_+_17794251 0.10 ENST00000377495.1
ENST00000338221.5
TMEM236
transmembrane protein 236
chr3_+_122399444 0.10 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr7_-_82792215 0.10 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr12_+_20848377 0.10 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr15_-_60690163 0.10 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr14_-_21924209 0.10 ENST00000557364.1
CHD8
chromodomain helicase DNA binding protein 8
chr8_-_123139423 0.09 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chrX_+_149861836 0.09 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
MTMR1
myotubularin related protein 1
chr16_+_24549014 0.09 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr10_+_104404644 0.09 ENST00000462202.2
TRIM8
tripartite motif containing 8
chr6_-_116833500 0.09 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr19_-_56904799 0.09 ENST00000589895.1
ENST00000589143.1
ENST00000301310.4
ENST00000586929.1
ZNF582
zinc finger protein 582
chr6_+_25754927 0.09 ENST00000377905.4
ENST00000439485.2
SLC17A4
solute carrier family 17, member 4
chr19_-_7812397 0.08 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
CD209
CD209 molecule
chr10_+_6625733 0.08 ENST00000607982.1
ENST00000608526.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr5_+_32585605 0.08 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1
SUB1 homolog (S. cerevisiae)
chr14_+_69658480 0.08 ENST00000409949.1
ENST00000409242.1
ENST00000312994.5
ENST00000413191.1
EXD2
exonuclease 3'-5' domain containing 2
chrX_+_24711997 0.07 ENST00000379068.3
ENST00000379059.3
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr1_-_161519682 0.07 ENST00000367969.3
ENST00000443193.1
FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr14_-_81408063 0.07 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr4_-_140477353 0.07 ENST00000406354.1
ENST00000506866.2
SETD7
SET domain containing (lysine methyltransferase) 7
chr13_-_26795840 0.07 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6
ring finger protein (C3H2C3 type) 6
chr15_+_42131011 0.07 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr1_+_50571949 0.07 ENST00000357083.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr1_-_185597619 0.07 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr4_-_46126093 0.07 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr19_-_44405623 0.06 ENST00000591815.1
RP11-15A1.3
RP11-15A1.3
chr17_-_27038063 0.06 ENST00000439862.3
PROCA1
protein interacting with cyclin A1
chr12_+_70636765 0.06 ENST00000552231.1
ENST00000229195.3
ENST00000547780.1
ENST00000418359.3
CNOT2
CCR4-NOT transcription complex, subunit 2
chr3_+_77088989 0.06 ENST00000461745.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr20_+_39657454 0.06 ENST00000361337.2
TOP1
topoisomerase (DNA) I
chr6_+_31082603 0.06 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr8_-_114449112 0.06 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr19_-_7812446 0.05 ENST00000394173.4
ENST00000301357.8
CD209
CD209 molecule
chr17_-_5323480 0.05 ENST00000573584.1
NUP88
nucleoporin 88kDa
chr8_-_27469196 0.05 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr3_+_155838337 0.04 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr14_+_24630465 0.04 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr19_-_54663473 0.04 ENST00000222224.3
LENG1
leukocyte receptor cluster (LRC) member 1
chr12_-_11139511 0.04 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr19_-_39881777 0.04 ENST00000595564.1
ENST00000221265.3
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr6_+_108977520 0.03 ENST00000540898.1
FOXO3
forkhead box O3
chr2_-_37193606 0.03 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chrX_-_107334790 0.03 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr1_+_179699318 0.03 ENST00000423879.1
RP11-12M5.1
RP11-12M5.1
chr1_-_144994840 0.03 ENST00000369351.3
ENST00000369349.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr2_-_84686552 0.03 ENST00000393868.2
SUCLG1
succinate-CoA ligase, alpha subunit
chr9_-_27297126 0.03 ENST00000380031.1
ENST00000537675.1
ENST00000380032.3
EQTN
equatorin, sperm acrosome associated
chr19_-_44405941 0.03 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr12_+_20848486 0.03 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chrX_+_100646190 0.03 ENST00000471855.1
RPL36A
ribosomal protein L36a
chr19_+_44669221 0.02 ENST00000590578.1
ENST00000589160.1
ENST00000337433.5
ENST00000586286.1
ENST00000585560.1
ENST00000586914.1
ENST00000588883.1
ENST00000413984.2
ENST00000588742.1
ENST00000300823.6
ENST00000585678.1
ENST00000586203.1
ENST00000590467.1
ENST00000588795.1
ENST00000588127.1
ZNF226
zinc finger protein 226

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.7 2.0 GO:0061567 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.4 1.3 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.7 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.4 GO:0071284 cellular response to lead ion(GO:0071284)
0.2 0.5 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 2.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.5 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.7 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.3 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.3 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.2 GO:0060435 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435)
0.1 1.7 GO:0006825 copper ion transport(GO:0006825)
0.1 0.3 GO:1902617 response to fluoride(GO:1902617)
0.0 0.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 3.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427)
0.0 0.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.4 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 2.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.0 GO:0043317 regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 4.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 1.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 2.7 GO:0030426 growth cone(GO:0030426)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.4 1.3 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.4 1.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 4.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 2.0 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.2 1.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 2.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.5 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 2.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions