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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for T

Z-value: 0.67

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Transcription factors associated with T

Gene Symbol Gene ID Gene Info
T
ENSG00000164458.5 T

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Thg19_v2_chr6_-_166582107_1665821880.096.3e-01Click!

Activity profile of T motif

Sorted Z-values of T motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153029980 3.04 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr12_-_52845910 2.22 ENST00000252252.3
KRT6B
keratin 6B
chr1_-_153066998 2.19 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr10_+_94833642 2.18 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr14_+_75746781 2.15 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr21_+_30502806 1.89 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr12_+_22778291 1.56 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr2_-_216003127 1.51 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr9_+_36572851 1.48 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr7_+_134576317 1.23 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr19_-_44174330 1.17 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr12_-_6961050 1.14 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr9_+_40028620 1.13 ENST00000426179.1
AL353791.1
AL353791.1
chr9_+_139553306 1.05 ENST00000371699.1
EGFL7
EGF-like-domain, multiple 7
chr19_-_44174305 1.03 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr12_-_69326940 1.01 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM
carboxypeptidase M
chr19_+_7030589 1.01 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr12_-_6960407 1.00 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr19_+_7049332 0.99 ENST00000381393.3
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr7_-_76255444 0.96 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr2_-_85636928 0.94 ENST00000449030.1
CAPG
capping protein (actin filament), gelsolin-like
chr20_+_44637526 0.92 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr5_+_54320078 0.91 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr20_+_32951070 0.86 ENST00000535650.1
ENST00000262650.6
ITCH
itchy E3 ubiquitin protein ligase
chr19_+_11546093 0.85 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr21_-_45078019 0.85 ENST00000542962.1
HSF2BP
heat shock transcription factor 2 binding protein
chr7_-_28220354 0.85 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr19_+_11546440 0.84 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr2_+_234601512 0.83 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr19_+_11546153 0.82 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr1_-_24126023 0.80 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chr11_+_133938820 0.79 ENST00000299106.4
ENST00000529443.2
JAM3
junctional adhesion molecule 3
chr5_+_14664762 0.79 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr17_+_17942684 0.77 ENST00000376345.3
GID4
GID complex subunit 4
chr11_+_133938955 0.77 ENST00000534549.1
ENST00000441717.3
JAM3
junctional adhesion molecule 3
chr17_+_34538310 0.76 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1
chemokine (C-C motif) ligand 4-like 1
chr1_-_204135450 0.75 ENST00000272190.8
ENST00000367195.2
REN
renin
chr17_-_74497432 0.74 ENST00000590288.1
ENST00000313080.4
ENST00000592123.1
ENST00000591255.1
ENST00000585989.1
ENST00000591697.1
ENST00000389760.4
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr7_-_38370536 0.73 ENST00000390343.2
TRGV8
T cell receptor gamma variable 8
chr12_-_52867569 0.72 ENST00000252250.6
KRT6C
keratin 6C
chr2_-_208030647 0.68 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr14_+_96722539 0.65 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr17_+_26662597 0.64 ENST00000544907.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr20_-_1309809 0.63 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr10_-_5060147 0.63 ENST00000604507.1
AKR1C2
aldo-keto reductase family 1, member C2
chr3_-_57678772 0.62 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr1_-_150980828 0.61 ENST00000361936.5
ENST00000361738.6
FAM63A
family with sequence similarity 63, member A
chr21_-_31869451 0.59 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr10_-_76868931 0.55 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr17_+_34640031 0.55 ENST00000339270.6
ENST00000482104.1
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr6_-_26124138 0.53 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr7_+_110731062 0.52 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr17_+_34639793 0.52 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr12_-_117318788 0.51 ENST00000550505.1
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr2_+_33661382 0.51 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_24126051 0.50 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr4_-_73434498 0.50 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr1_-_156542328 0.49 ENST00000361170.2
IQGAP3
IQ motif containing GTPase activating protein 3
chr6_-_29324054 0.48 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr20_-_60942361 0.48 ENST00000252999.3
LAMA5
laminin, alpha 5
chr10_-_5060201 0.48 ENST00000407674.1
AKR1C2
aldo-keto reductase family 1, member C2
chr11_-_85779971 0.46 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr17_+_19281034 0.46 ENST00000308406.5
ENST00000299612.7
MAPK7
mitogen-activated protein kinase 7
chr20_-_44298878 0.45 ENST00000324384.3
ENST00000356562.2
WFDC11
WAP four-disulfide core domain 11
chr19_-_17958771 0.45 ENST00000534444.1
JAK3
Janus kinase 3
chr16_+_69458537 0.45 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr1_-_13052998 0.44 ENST00000436041.1
WI2-3308P17.2
Uncharacterized protein
chr10_+_5488564 0.44 ENST00000449083.1
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr17_+_47296865 0.43 ENST00000573347.1
ABI3
ABI family, member 3
chr19_-_10514184 0.43 ENST00000589629.1
ENST00000222005.2
CDC37
cell division cycle 37
chr17_+_57970469 0.42 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr11_+_120081475 0.42 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr17_+_17942594 0.39 ENST00000268719.4
GID4
GID complex subunit 4
chr2_-_61245363 0.39 ENST00000316752.6
PUS10
pseudouridylate synthase 10
chr10_-_23003460 0.39 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr12_-_49351228 0.39 ENST00000541959.1
ENST00000447318.2
ARF3
ADP-ribosylation factor 3
chr2_+_223162866 0.38 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr3_+_102153859 0.37 ENST00000306176.1
ENST00000466937.1
ZPLD1
zona pellucida-like domain containing 1
chr20_-_31124186 0.35 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr7_+_107220660 0.35 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr4_+_123300664 0.34 ENST00000388725.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr22_+_19929130 0.33 ENST00000361682.6
ENST00000403184.1
ENST00000403710.1
ENST00000407537.1
COMT
catechol-O-methyltransferase
chr16_+_67313412 0.33 ENST00000379344.3
ENST00000568621.1
ENST00000450733.1
ENST00000567938.1
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr2_-_103353277 0.33 ENST00000258436.5
MFSD9
major facilitator superfamily domain containing 9
chr1_+_78245303 0.32 ENST00000370791.3
ENST00000443751.2
FAM73A
family with sequence similarity 73, member A
chr6_+_29079668 0.32 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chrX_-_69509738 0.30 ENST00000374454.1
ENST00000239666.4
PDZD11
PDZ domain containing 11
chrX_+_100353153 0.29 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
CENPI
centromere protein I
chr7_-_752577 0.29 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr19_+_7895074 0.28 ENST00000270530.4
EVI5L
ecotropic viral integration site 5-like
chr11_-_66112555 0.28 ENST00000425825.2
ENST00000359957.3
BRMS1
breast cancer metastasis suppressor 1
chr15_-_83474806 0.27 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr20_+_32951041 0.27 ENST00000374864.4
ITCH
itchy E3 ubiquitin protein ligase
chr1_+_39456895 0.27 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr8_+_7801144 0.26 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr3_-_126373929 0.26 ENST00000523403.1
ENST00000524230.2
TXNRD3
thioredoxin reductase 3
chr17_-_74533734 0.26 ENST00000589342.1
CYGB
cytoglobin
chrX_+_79591003 0.26 ENST00000538312.1
FAM46D
family with sequence similarity 46, member D
chr4_-_186456652 0.26 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chrX_-_48216101 0.26 ENST00000298396.2
ENST00000376893.3
SSX3
synovial sarcoma, X breakpoint 3
chr3_-_52002403 0.26 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr17_-_40306934 0.25 ENST00000592574.1
ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
CTD-2132N18.3
RAB5C
Uncharacterized protein
RAB5C, member RAS oncogene family
chr17_-_56084578 0.25 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
SRSF1
serine/arginine-rich splicing factor 1
chr4_-_186456766 0.24 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr1_+_113009163 0.24 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr17_-_17942473 0.24 ENST00000585101.1
ENST00000474627.3
ENST00000444058.1
ATPAF2
ATP synthase mitochondrial F1 complex assembly factor 2
chr5_-_176433350 0.24 ENST00000377227.4
ENST00000377219.2
UIMC1
ubiquitin interaction motif containing 1
chr1_+_101702417 0.24 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr1_+_150980889 0.23 ENST00000450884.1
ENST00000271620.3
ENST00000271619.8
ENST00000368937.1
ENST00000431193.1
ENST00000368936.1
PRUNE
prune exopolyphosphatase
chr14_-_74025625 0.22 ENST00000553558.1
ENST00000563329.1
ENST00000334988.2
ENST00000560393.1
HEATR4
HEAT repeat containing 4
chr8_-_141810634 0.22 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr2_-_27341966 0.21 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
CGREF1
cell growth regulator with EF-hand domain 1
chr2_-_241737128 0.21 ENST00000404283.3
KIF1A
kinesin family member 1A
chr12_-_53074182 0.21 ENST00000252244.3
KRT1
keratin 1
chr21_-_15918618 0.21 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_33679452 0.20 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
UQCC2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr22_-_36031181 0.20 ENST00000594060.1
AL049747.1
AL049747.1
chr12_+_57610562 0.19 ENST00000349394.5
NXPH4
neurexophilin 4
chr2_+_58134756 0.19 ENST00000435505.2
ENST00000417641.2
VRK2
vaccinia related kinase 2
chr2_+_176972000 0.18 ENST00000249504.5
HOXD11
homeobox D11
chr22_-_46644182 0.18 ENST00000404583.1
ENST00000404744.1
CDPF1
cysteine-rich, DPF motif domain containing 1
chr14_-_94984181 0.17 ENST00000341228.2
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr4_+_158493642 0.16 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
RP11-364P22.1
chr2_+_108905095 0.16 ENST00000251481.6
ENST00000326853.5
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr10_-_115423792 0.16 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
NRAP
nebulin-related anchoring protein
chr4_+_128554081 0.16 ENST00000335251.6
ENST00000296461.5
INTU
inturned planar cell polarity protein
chr6_+_83073334 0.16 ENST00000369750.3
TPBG
trophoblast glycoprotein
chr2_+_133874577 0.15 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr10_-_97050777 0.15 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chr7_-_229557 0.15 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr16_+_77233294 0.15 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr1_-_204165610 0.14 ENST00000367194.4
KISS1
KiSS-1 metastasis-suppressor
chr12_+_54378923 0.14 ENST00000303460.4
HOXC10
homeobox C10
chr2_+_27498289 0.14 ENST00000296097.3
ENST00000420191.1
DNAJC5G
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr12_-_49351303 0.14 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr2_+_27498331 0.14 ENST00000402462.1
ENST00000404433.1
ENST00000406962.1
DNAJC5G
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr5_+_139554227 0.14 ENST00000261811.4
CYSTM1
cysteine-rich transmembrane module containing 1
chr1_+_89150245 0.13 ENST00000370513.5
PKN2
protein kinase N2
chr2_+_162087577 0.13 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr3_+_57741957 0.13 ENST00000295951.3
SLMAP
sarcolemma associated protein
chr17_-_46657473 0.12 ENST00000332503.5
HOXB4
homeobox B4
chr16_+_72459838 0.12 ENST00000564508.1
AC004158.3
AC004158.3
chr4_-_151936865 0.12 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr21_+_27107672 0.11 ENST00000400075.3
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr2_-_200322723 0.11 ENST00000417098.1
SATB2
SATB homeobox 2
chr11_-_62995986 0.10 ENST00000403374.2
SLC22A25
solute carrier family 22, member 25
chr2_+_171571827 0.10 ENST00000375281.3
SP5
Sp5 transcription factor
chr14_-_107211459 0.10 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chrX_+_16804544 0.10 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr14_-_69619689 0.10 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DCAF5
DDB1 and CUL4 associated factor 5
chr19_+_55235969 0.09 ENST00000402254.2
ENST00000538269.1
ENST00000541392.1
ENST00000291860.1
ENST00000396284.2
KIR3DL1
KIR3DL3
KIR2DL4
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr19_-_1021113 0.09 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr17_-_43502987 0.09 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr4_-_69817481 0.09 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chrX_-_106146547 0.09 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr14_+_101908402 0.09 ENST00000555725.1
RP11-168L7.3
RP11-168L7.3
chr20_+_1115821 0.08 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr7_-_81399329 0.08 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr5_+_85913721 0.08 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
COX7C
cytochrome c oxidase subunit VIIc
chr22_+_40441456 0.08 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chr16_+_69221028 0.08 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr8_-_99954788 0.07 ENST00000523601.1
STK3
serine/threonine kinase 3
chr6_+_26158343 0.07 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chr2_+_108905325 0.07 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr1_+_89149905 0.07 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
PKN2
protein kinase N2
chr12_+_128399917 0.07 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr5_-_137610300 0.07 ENST00000274721.3
GFRA3
GDNF family receptor alpha 3
chr2_+_233320827 0.07 ENST00000295463.3
ALPI
alkaline phosphatase, intestinal
chr22_-_32341336 0.06 ENST00000248984.3
C22orf24
chromosome 22 open reading frame 24
chr22_-_41215291 0.06 ENST00000542412.1
ENST00000544408.1
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr20_-_43438912 0.06 ENST00000541604.2
ENST00000372851.3
RIMS4
regulating synaptic membrane exocytosis 4
chr6_+_24126350 0.06 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1
neurensin 1
chr1_+_92417716 0.05 ENST00000402388.1
BRDT
bromodomain, testis-specific
chr1_-_25256368 0.04 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr12_+_19358228 0.04 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr8_-_38326119 0.04 ENST00000356207.5
ENST00000326324.6
FGFR1
fibroblast growth factor receptor 1
chr10_-_79789291 0.04 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr5_-_137610254 0.04 ENST00000378362.3
GFRA3
GDNF family receptor alpha 3
chrX_+_153665248 0.04 ENST00000447750.2
GDI1
GDP dissociation inhibitor 1
chr1_-_205290865 0.04 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr7_+_117864708 0.04 ENST00000357099.4
ENST00000265224.4
ENST00000486422.1
ENST00000417525.1
ANKRD7
ankyrin repeat domain 7
chr15_+_78832747 0.03 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr18_-_77276057 0.03 ENST00000597412.1
AC018445.1
Uncharacterized protein
chr6_+_43149903 0.03 ENST00000252050.4
ENST00000354495.3
ENST00000372647.2
CUL9
cullin 9
chr7_-_81399438 0.03 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr5_-_131330272 0.03 ENST00000379240.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr14_-_107114267 0.03 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr7_+_117864815 0.03 ENST00000433239.1
ANKRD7
ankyrin repeat domain 7
chr19_+_17638059 0.02 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr14_-_45603657 0.02 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr11_-_64889252 0.02 ENST00000525297.1
ENST00000529259.1
FAU
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr3_+_38307293 0.02 ENST00000311856.4
SLC22A13
solute carrier family 22 (organic anion/urate transporter), member 13
chr3_-_100712292 0.02 ENST00000495063.1
ENST00000530539.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr7_-_81399411 0.02 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr16_-_2314222 0.02 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr8_-_114449112 0.01 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr17_-_33446820 0.01 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr14_+_95078714 0.01 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr5_-_131329918 0.01 ENST00000357096.1
ENST00000431707.1
ENST00000434099.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr2_+_189839046 0.01 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of T

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.5 2.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 1.5 GO:0035627 ceramide transport(GO:0035627)
0.3 2.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 1.1 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.2 1.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 1.0 GO:0035803 egg coat formation(GO:0035803)
0.2 1.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 0.9 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.4 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.4 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.1 0.8 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.3 GO:0019388 galactose catabolic process(GO:0019388)
0.1 2.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 2.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.5 GO:0030820 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 5.4 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.3 GO:0016036 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1 0.5 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.2 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.1 1.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.6 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 2.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 1.5 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.7 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0035976 AP1 complex(GO:0035976)
0.2 1.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 2.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.5 GO:0043260 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.1 1.6 GO:0033010 paranodal junction(GO:0033010)
0.1 1.2 GO:0030478 actin cap(GO:0030478)
0.1 5.0 GO:0001533 cornified envelope(GO:0001533)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 2.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 2.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.4 2.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.4 1.5 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.3 1.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 0.6 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 1.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.2 2.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.0 GO:0032190 acrosin binding(GO:0032190)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 1.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 2.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.8 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 2.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 2.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 2.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 2.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane