Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for TBP
Z-value: 1.83
Motif logo
Transcription factors associated with TBP
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TBP | hg19_v2_chr6_+_170863421_170863484 | 0.28 | 1.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_23261589 Show fit | 10.08 |
ENST00000524168.1
ENST00000523833.2 ENST00000519243.1 ENST00000389131.3 |
lysyl oxidase-like 2 |
|
| chr1_-_153044083 Show fit | 9.04 |
ENST00000341611.2
|
small proline-rich protein 2B |
|
| chr1_-_153013588 Show fit | 7.98 |
ENST00000360379.3
|
small proline-rich protein 2D |
|
| chr15_+_45722727 Show fit | 7.21 |
ENST00000396650.2
ENST00000558435.1 ENST00000344300.3 |
chromosome 15 open reading frame 48 |
|
| chr12_-_52845910 Show fit | 6.63 |
ENST00000252252.3
|
keratin 6B |
|
| chr8_-_133097902 Show fit | 6.50 |
ENST00000262283.5
|
Otoconin-90 |
|
| chr4_-_57547454 Show fit | 6.41 |
ENST00000556376.2
|
HOP homeobox |
|
| chr4_-_57547870 Show fit | 6.31 |
ENST00000381260.3
ENST00000420433.1 ENST00000554144.1 ENST00000557328.1 |
HOP homeobox |
|
| chr21_-_28217721 Show fit | 6.14 |
ENST00000284984.3
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
|
| chr12_+_4385230 Show fit | 5.95 |
ENST00000536537.1
|
cyclin D2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TBP
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 42.9 | GO:0070268 | cornification(GO:0070268) |
| 0.4 | 12.0 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.3 | 10.1 | GO:0032332 | positive regulation of chondrocyte differentiation(GO:0032332) |
| 1.9 | 9.6 | GO:0060356 | leucine import(GO:0060356) |
| 0.3 | 8.5 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.1 | 7.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 1.4 | 6.8 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 0.2 | 6.5 | GO:0050482 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
| 0.4 | 6.4 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.3 | 6.3 | GO:0071481 | cellular response to X-ray(GO:0071481) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 24.1 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 21.4 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.3 | 17.9 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 15.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 10.5 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 7.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.2 | 7.5 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 6.3 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 1.0 | 6.0 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 1.4 | 5.8 | GO:1990742 | microvesicle(GO:1990742) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 33.7 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 15.4 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.1 | 11.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 2.0 | 10.1 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.6 | 9.6 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.1 | 7.7 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 7.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 6.8 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 6.6 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.1 | 6.0 | GO:0008327 | methyl-CpG binding(GO:0008327) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 23.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 7.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.2 | 6.9 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 6.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 6.5 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 6.1 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 6.0 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.2 | 5.8 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 5.6 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 5.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 18.3 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.3 | 12.1 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.2 | 8.2 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 7.6 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.4 | 7.1 | REACTOME PEPTIDE HORMONE BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
| 0.1 | 6.0 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.2 | 5.8 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.3 | 5.5 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.3 | 5.3 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.2 | 5.1 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |