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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TBX15_MGA

Z-value: 0.63

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Transcription factors associated with TBX15_MGA

Gene Symbol Gene ID Gene Info
TBX15
ENSG00000092607.9 T-box transcription factor 15
MGA
ENSG00000174197.12 MAX dimerization protein MGA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MGAhg19_v2_chr15_+_41952591_41952672-0.504.5e-03Click!
TBX15hg19_v2_chr1_-_119530428_119530572,
hg19_v2_chr1_-_119532127_119532179		0.115.5e-01Click!

Activity profile of TBX15_MGA motif

Sorted Z-values of TBX15_MGA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153066998 2.56 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr21_+_30502806 2.43 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr14_+_75746781 2.07 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr4_+_8582287 1.57 ENST00000382487.4
GPR78
G protein-coupled receptor 78
chr1_-_153029980 1.47 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr7_-_76255444 1.43 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr1_-_153044083 1.38 ENST00000341611.2
SPRR2B
small proline-rich protein 2B
chr7_-_27135591 1.29 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr18_+_47088401 1.27 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chr1_+_15736359 1.25 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr1_+_150522222 1.15 ENST00000369039.5
ADAMTSL4
ADAMTS-like 4
chr5_+_133861339 1.13 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr9_+_34990219 1.12 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr2_-_31637560 1.11 ENST00000379416.3
XDH
xanthine dehydrogenase
chr14_+_67291158 1.07 ENST00000555456.1
GPHN
gephyrin
chrX_+_99899180 1.06 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr7_+_143013198 1.02 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr11_-_119599794 1.01 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr17_+_9066252 1.01 ENST00000436734.1
NTN1
netrin 1
chr17_-_39216344 0.98 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr20_+_44509857 0.98 ENST00000372523.1
ENST00000372520.1
ZSWIM1
zinc finger, SWIM-type containing 1
chr9_+_139847347 0.97 ENST00000371632.3
LCN12
lipocalin 12
chr19_+_39279838 0.93 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr7_-_142120321 0.90 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr3_-_197024394 0.90 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr20_+_62492566 0.88 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chrX_-_153775426 0.88 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr1_-_205744205 0.86 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr10_+_95256356 0.81 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr11_-_7847519 0.79 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr5_-_132112907 0.77 ENST00000458488.2
SEPT8
septin 8
chr11_-_85779971 0.75 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr15_+_89922345 0.73 ENST00000558982.1
LINC00925
long intergenic non-protein coding RNA 925
chrX_+_16804544 0.72 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr4_-_57547870 0.72 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr5_-_132112921 0.72 ENST00000378721.4
ENST00000378701.1
SEPT8
septin 8
chr12_+_22778291 0.71 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr21_+_37507210 0.70 ENST00000290354.5
CBR3
carbonyl reductase 3
chr22_-_20231207 0.70 ENST00000425986.1
RTN4R
reticulon 4 receptor
chr13_-_99667960 0.68 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr1_-_111174054 0.68 ENST00000369770.3
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr12_-_49351228 0.67 ENST00000541959.1
ENST00000447318.2
ARF3
ADP-ribosylation factor 3
chrX_+_69642881 0.66 ENST00000453994.2
ENST00000536730.1
ENST00000538649.1
ENST00000374382.3
GDPD2
glycerophosphodiester phosphodiesterase domain containing 2
chr11_+_18477369 0.65 ENST00000396213.3
ENST00000280706.2
LDHAL6A
lactate dehydrogenase A-like 6A
chr1_-_182641367 0.62 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr12_+_57853918 0.60 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr5_+_137514687 0.60 ENST00000394894.3
KIF20A
kinesin family member 20A
chr11_+_61447845 0.59 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr12_-_8815215 0.59 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr2_-_208030647 0.59 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_-_39222131 0.59 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr12_-_8815299 0.59 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr17_+_40704938 0.58 ENST00000225929.5
HSD17B1
hydroxysteroid (17-beta) dehydrogenase 1
chr6_+_36646435 0.58 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr11_-_7818520 0.58 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chrX_+_56259316 0.57 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr12_-_57634475 0.56 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr17_-_43209862 0.56 ENST00000322765.5
PLCD3
phospholipase C, delta 3
chr11_-_62752162 0.56 ENST00000458333.2
ENST00000421062.2
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr4_+_156680518 0.56 ENST00000513437.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr19_+_54926621 0.55 ENST00000376530.3
ENST00000445095.1
ENST00000391739.3
ENST00000376531.3
TTYH1
tweety family member 1
chrX_+_135230712 0.55 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr19_+_54926601 0.53 ENST00000301194.4
TTYH1
tweety family member 1
chr2_-_216003127 0.53 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr17_-_40333099 0.53 ENST00000607371.1
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr17_+_76210267 0.53 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr5_-_9630463 0.52 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr10_-_75226166 0.52 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr5_-_54281407 0.51 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr1_-_11907829 0.50 ENST00000376480.3
NPPA
natriuretic peptide A
chr3_+_4535155 0.50 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr6_+_121756809 0.50 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr1_+_154975258 0.49 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr4_-_170924888 0.49 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr9_+_124461603 0.48 ENST00000373782.3
DAB2IP
DAB2 interacting protein
chr12_-_7848364 0.47 ENST00000329913.3
GDF3
growth differentiation factor 3
chr4_+_156680143 0.47 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr2_-_27718052 0.47 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr12_+_65672702 0.47 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr14_+_55033815 0.46 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr11_-_28129656 0.45 ENST00000263181.6
KIF18A
kinesin family member 18A
chr2_-_40680578 0.45 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr4_+_166248775 0.45 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr19_-_46526304 0.44 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr17_+_76210367 0.44 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr3_+_167453493 0.44 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr15_+_60296421 0.43 ENST00000396057.4
FOXB1
forkhead box B1
chr9_+_17134980 0.43 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr12_-_48152853 0.43 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr1_+_153950202 0.42 ENST00000608236.1
RP11-422P24.11
RP11-422P24.11
chr6_-_40555176 0.42 ENST00000338305.6
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr2_+_201994208 0.42 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr12_-_13529642 0.42 ENST00000318426.2
C12orf36
chromosome 12 open reading frame 36
chr17_+_7210294 0.42 ENST00000336452.7
EIF5A
eukaryotic translation initiation factor 5A
chr4_+_156680153 0.41 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr17_+_39975544 0.41 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr19_-_46418033 0.41 ENST00000341294.2
NANOS2
nanos homolog 2 (Drosophila)
chr6_+_45390222 0.41 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chrX_+_15808569 0.41 ENST00000380308.3
ENST00000307771.7
ZRSR2
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr12_+_104324112 0.41 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr14_+_21467414 0.40 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr12_-_48152611 0.40 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr17_-_34122596 0.40 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr6_+_43739697 0.40 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr17_+_39975455 0.40 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr17_-_46657473 0.40 ENST00000332503.5
HOXB4
homeobox B4
chr15_+_76016293 0.39 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr19_-_11689752 0.39 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chrX_-_131623874 0.39 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chrX_+_70443050 0.38 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr1_+_28586006 0.38 ENST00000253063.3
SESN2
sestrin 2
chr15_+_90319557 0.37 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr20_+_43343476 0.37 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr12_-_85306594 0.37 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr19_-_14217672 0.37 ENST00000587372.1
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr5_+_113697983 0.36 ENST00000264773.3
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chrX_+_101380642 0.36 ENST00000372780.1
ENST00000329035.2
TCEAL2
transcription elongation factor A (SII)-like 2
chr7_-_27142290 0.36 ENST00000222718.5
HOXA2
homeobox A2
chrX_-_106146547 0.36 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr17_-_8066843 0.36 ENST00000404970.3
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr6_-_131321863 0.36 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr9_+_75766763 0.35 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr7_+_2687173 0.35 ENST00000403167.1
TTYH3
tweety family member 3
chr17_-_1619535 0.35 ENST00000573075.1
ENST00000574306.1
MIR22HG
MIR22 host gene (non-protein coding)
chr2_+_176972000 0.35 ENST00000249504.5
HOXD11
homeobox D11
chr16_+_3162557 0.35 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
ZNF205
zinc finger protein 205
chr14_+_55034599 0.35 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr13_+_109248500 0.34 ENST00000356711.2
MYO16
myosin XVI
chrX_-_109561294 0.34 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr2_+_62932779 0.34 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1
EH domain binding protein 1
chr12_+_18891045 0.34 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr8_+_102504651 0.34 ENST00000251808.3
ENST00000521085.1
GRHL2
grainyhead-like 2 (Drosophila)
chr19_-_36001286 0.34 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN
dermokine
chr20_+_43343517 0.33 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr3_+_127770455 0.33 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr14_+_55034330 0.33 ENST00000251091.5
SAMD4A
sterile alpha motif domain containing 4A
chr17_-_1619491 0.33 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22HG
MIR22 host gene (non-protein coding)
chr1_+_41445413 0.33 ENST00000541520.1
CTPS1
CTP synthase 1
chr20_+_43343886 0.33 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr5_+_137514834 0.32 ENST00000508792.1
ENST00000504621.1
KIF20A
kinesin family member 20A
chr20_-_22565101 0.32 ENST00000419308.2
FOXA2
forkhead box A2
chr19_-_42916499 0.32 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr2_+_201994042 0.32 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_+_38206975 0.31 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr2_+_62933001 0.31 ENST00000263991.5
ENST00000354487.3
EHBP1
EH domain binding protein 1
chr20_+_58630972 0.31 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr22_+_40441456 0.30 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chr1_-_94079648 0.30 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr1_-_226374373 0.30 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr14_-_55658323 0.30 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr12_-_49351303 0.30 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr21_-_31869451 0.30 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr2_+_219081817 0.29 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr3_+_4535025 0.29 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr11_-_107590383 0.29 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chr1_+_154377669 0.29 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr19_+_39390320 0.29 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr6_-_10419871 0.29 ENST00000319516.4
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr4_-_69111401 0.29 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr19_-_36001113 0.29 ENST00000434389.1
DMKN
dermokine
chr14_-_55658252 0.29 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr15_+_63481668 0.29 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B
RAB8B, member RAS oncogene family
chr12_-_48152428 0.29 ENST00000449771.2
ENST00000395358.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr17_+_38497640 0.28 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr21_-_46962379 0.28 ENST00000311124.4
ENST00000380010.4
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr8_+_11660227 0.28 ENST00000443614.2
ENST00000525900.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr17_-_10452929 0.28 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr19_+_45973120 0.28 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr19_-_39390350 0.28 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr1_+_202995611 0.28 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr16_+_28834531 0.28 ENST00000570200.1
ATXN2L
ataxin 2-like
chr12_-_102872317 0.28 ENST00000424202.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr17_+_57970469 0.28 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr15_+_41549105 0.28 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr3_-_197024965 0.27 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chrX_+_123480375 0.27 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr12_-_110011288 0.27 ENST00000540016.1
ENST00000266839.5
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type
chr11_-_6426635 0.27 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr4_+_140222609 0.27 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chrX_+_122318113 0.27 ENST00000371264.3
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr7_+_99724317 0.27 ENST00000398075.2
ENST00000421390.1
MBLAC1
metallo-beta-lactamase domain containing 1
chr1_+_154975110 0.27 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr11_-_66104237 0.26 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr5_+_169931249 0.26 ENST00000520740.1
KCNIP1
Kv channel interacting protein 1
chr5_+_54320078 0.26 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr5_+_150040403 0.26 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr1_-_19229014 0.26 ENST00000538839.1
ENST00000290597.5
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr19_-_38397285 0.26 ENST00000303868.5
WDR87
WD repeat domain 87
chr12_+_21525818 0.26 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr12_-_120554534 0.26 ENST00000538903.1
ENST00000534951.1
RAB35
RAB35, member RAS oncogene family
chr11_+_120081475 0.26 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr17_-_43502987 0.26 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr1_-_19229248 0.26 ENST00000375341.3
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr1_-_161207953 0.26 ENST00000367982.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr17_+_7210898 0.26 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr4_+_144354644 0.25 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr6_-_160166218 0.25 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr3_+_10857885 0.25 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr5_-_49737184 0.25 ENST00000508934.1
ENST00000303221.5
EMB
embigin
chr14_+_78870030 0.24 ENST00000553631.1
ENST00000554719.1
NRXN3
neurexin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX15_MGA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.3 1.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.3 0.9 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.3 1.1 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.3 1.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 0.8 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 1.9 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 1.4 GO:0035803 egg coat formation(GO:0035803)
0.2 1.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 1.7 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.2 0.6 GO:0097254 renal tubular secretion(GO:0097254)
0.2 0.8 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 1.4 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 0.4 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 0.7 GO:0036292 DNA rewinding(GO:0036292)
0.2 0.5 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 0.6 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.4 GO:0051714 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 0.7 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.4 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.8 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 1.6 GO:0021603 cranial nerve formation(GO:0021603)
0.1 0.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 1.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.6 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1 1.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.6 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.3 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.3 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.7 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.5 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.3 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.5 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.6 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.3 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.5 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.3 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.3 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.7 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.5 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.2 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 1.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.2 GO:0072004 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.2 GO:0055073 cadmium ion homeostasis(GO:0055073) divalent metal ion export(GO:0070839)
0.1 0.5 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.1 0.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.5 GO:0015820 leucine transport(GO:0015820)
0.1 0.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.2 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.2 GO:0043132 coenzyme A transport(GO:0015880) FAD transport(GO:0015883) coenzyme A transmembrane transport(GO:0035349) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 4.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.3 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:0048539 bone marrow development(GO:0048539)
0.1 0.3 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.2 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
0.0 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 1.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.0 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.7 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) septum secundum development(GO:0003285)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0045588 allantoin metabolic process(GO:0000255) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.3 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.2 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.7 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.7 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 1.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 2.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.3 GO:0097647 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 1.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.4 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.0 GO:0044254 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.2 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.4 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0006954 inflammatory response(GO:0006954)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.6 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:1900241 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796) intralumenal vesicle formation(GO:0070676)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.1 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.0 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 1.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 1.0 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 1.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.0 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.0 GO:0001764 neuron migration(GO:0001764)
0.0 2.0 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.4 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.0 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0089700 protein kinase D signaling(GO:0089700)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0035976 AP1 complex(GO:0035976)
0.2 0.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.6 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.5 GO:1990032 parallel fiber(GO:1990032)
0.1 0.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.5 GO:0043219 lateral loop(GO:0043219)
0.1 1.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.4 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 6.3 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.6 GO:0043196 varicosity(GO:0043196)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:0089701 U2AF(GO:0089701)
0.1 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0090543 Flemming body(GO:0090543)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0033010 paranodal junction(GO:0033010)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.0 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.3 0.9 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 0.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 0.7 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 0.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 0.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 1.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.2 1.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 2.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 0.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 1.4 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.5 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 1.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.3 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.4 GO:0005549 odorant binding(GO:0005549)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.3 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 2.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.1 0.3 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) FAD transmembrane transporter activity(GO:0015230) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.6 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 2.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.9 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.4 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.9 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.0 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.0 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.2 GO:0035254 glutamate receptor binding(GO:0035254) ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.9 PID AURORA A PATHWAY Aurora A signaling
0.0 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.1 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 3.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.4 REACTOME KINESINS Genes involved in Kinesins
0.0 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.4 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint