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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TBX21_TBR1

Z-value: 1.11

Motif logo

Transcription factors associated with TBX21_TBR1

Gene Symbol Gene ID Gene Info
ENSG00000073861.2 T-box transcription factor 21
ENSG00000136535.10 T-box brain transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX21hg19_v2_chr17_+_45810594_45810610-0.422.0e-02Click!
TBR1hg19_v2_chr2_+_162272605_1622727530.291.2e-01Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_94727048 15.32 ENST00000283357.5
family with sequence similarity 81, member B
chr1_+_38022572 14.19 ENST00000541606.1
dynein, axonemal, light intermediate chain 1
chr1_+_38022513 12.62 ENST00000296218.7
dynein, axonemal, light intermediate chain 1
chr11_+_73358594 10.39 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
pleckstrin homology domain containing, family B (evectins) member 1
chr19_-_7990991 8.56 ENST00000318978.4
cortexin 1
chr5_-_35938674 6.62 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
calcyphosine-like
chr4_-_177116772 6.41 ENST00000280191.2
spermatogenesis associated 4
chr2_+_228736321 5.24 ENST00000309931.2
dynein assembly factor with WDR repeat domains 1
chr7_-_120497178 5.12 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
tetraspanin 12
chr3_-_66551397 4.89 ENST00000383703.3
leucine-rich repeats and immunoglobulin-like domains 1
chr11_+_6260298 4.85 ENST00000379936.2
cyclic nucleotide gated channel alpha 4
chr2_+_228736335 4.75 ENST00000440997.1
ENST00000545118.1
dynein assembly factor with WDR repeat domains 1
chr3_-_66551351 4.67 ENST00000273261.3
leucine-rich repeats and immunoglobulin-like domains 1
chr3_-_100712352 4.44 ENST00000471714.1
ENST00000284322.5
ABI family, member 3 (NESH) binding protein
chr16_-_67450325 3.94 ENST00000348579.2
zinc finger, DHHC-type containing 1
chr13_-_39564993 3.55 ENST00000423210.1
stomatin (EPB72)-like 3
chr12_+_69742121 3.46 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
lysozyme
chr5_+_140571902 3.41 ENST00000239446.4
protocadherin beta 10
chr17_-_56406117 3.39 ENST00000268893.6
ENST00000355701.3
benzodiazepine receptor (peripheral) associated protein 1
chr19_+_36236514 3.36 ENST00000222266.2
presenilin enhancer gamma secretase subunit
chr19_+_36236491 3.33 ENST00000591949.1
presenilin enhancer gamma secretase subunit
chr1_+_47264711 3.25 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
cytochrome P450, family 4, subfamily B, polypeptide 1
chr17_+_35849937 2.99 ENST00000394389.4
dual specificity phosphatase 14
chr14_+_95078714 2.97 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr8_+_75896731 2.79 ENST00000262207.4
cysteine-rich secretory protein LCCL domain containing 1
chr1_+_212782012 2.66 ENST00000341491.4
ENST00000366985.1
activating transcription factor 3
chr7_-_138386097 2.56 ENST00000421622.1
SVOP-like
chrX_+_53449887 2.54 ENST00000375327.3
RIB43A domain with coiled-coils 1
chr2_-_157189180 2.52 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
nuclear receptor subfamily 4, group A, member 2
chr1_-_26633067 2.47 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBX domain protein 11
chr22_+_31003133 2.45 ENST00000405742.3
transcobalamin II
chr1_-_46598371 2.45 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr22_+_31003190 2.42 ENST00000407817.3
transcobalamin II
chr1_-_46598284 2.34 ENST00000423209.1
ENST00000262741.5
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr16_+_30212378 2.30 ENST00000569485.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr9_-_75567962 2.26 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr11_-_47736896 2.22 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
ATP/GTP binding protein-like 2
chr12_+_56473939 2.21 ENST00000450146.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr9_+_26956371 2.11 ENST00000380062.5
ENST00000518614.1
intraflagellar transport 74 homolog (Chlamydomonas)
chr5_-_68628543 2.07 ENST00000396496.2
ENST00000511257.1
ENST00000383374.2
coiled-coil domain containing 125
chr10_+_114135004 2.04 ENST00000393081.1
acyl-CoA synthetase long-chain family member 5
chr6_+_39760129 2.00 ENST00000274867.4
dishevelled associated activator of morphogenesis 2
chr6_-_52705641 2.00 ENST00000370989.2
glutathione S-transferase alpha 5
chr1_+_182758900 1.89 ENST00000367555.1
ENST00000367554.3
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr1_-_108743471 1.86 ENST00000569674.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr11_+_45907177 1.86 ENST00000241014.2
mitogen-activated protein kinase 8 interacting protein 1
chrX_+_105412290 1.84 ENST00000357175.2
ENST00000337685.2
melanoma associated antigen (mutated) 1-like 1
chr17_-_7232585 1.81 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
neuralized E3 ubiquitin protein ligase 4
chrX_+_53449805 1.81 ENST00000414955.2
RIB43A domain with coiled-coils 1
chr2_+_98703643 1.80 ENST00000477737.1
von Willebrand factor A domain containing 3B
chr10_+_118305435 1.78 ENST00000369221.2
pancreatic lipase
chr1_-_85930246 1.77 ENST00000426972.3
dimethylarginine dimethylaminohydrolase 1
chr4_-_70518941 1.75 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr12_-_90024360 1.74 ENST00000393164.2
ATPase, Ca++ transporting, plasma membrane 1
chr14_+_77582905 1.74 ENST00000557408.1
transmembrane protein 63C
chr10_+_45406627 1.71 ENST00000389583.4
transmembrane protein 72
chr11_+_64073699 1.67 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr15_-_83316254 1.66 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr5_-_74807418 1.59 ENST00000405807.4
ENST00000261415.7
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr1_+_16062820 1.58 ENST00000294454.5
solute carrier family 25, member 34
chr11_-_33913708 1.55 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr12_-_57443886 1.53 ENST00000300119.3
myosin IA
chr7_-_138363824 1.52 ENST00000419765.3
SVOP-like
chr20_+_44098346 1.50 ENST00000372676.3
WAP four-disulfide core domain 2
chr19_-_50529193 1.44 ENST00000596445.1
ENST00000599538.1
vaccinia related kinase 3
chr8_+_1993173 1.38 ENST00000523438.1
myomesin 2
chr7_-_100026280 1.38 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr7_-_87849340 1.33 ENST00000419179.1
ENST00000265729.2
sorcin
chr11_-_6440624 1.31 ENST00000311051.3
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr17_+_30771279 1.29 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr11_-_236326 1.26 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
sirtuin 3
chr11_+_17756279 1.26 ENST00000265969.6
potassium voltage-gated channel, Shaw-related subfamily, member 1
chr6_-_46922659 1.25 ENST00000265417.7
G protein-coupled receptor 116
chr15_+_41913690 1.24 ENST00000563576.1
MGA, MAX dimerization protein
chr20_+_44098385 1.24 ENST00000217425.5
ENST00000339946.3
WAP four-disulfide core domain 2
chrX_-_132549506 1.21 ENST00000370828.3
glypican 4
chr12_+_12202774 1.20 ENST00000589718.1
BCL2-like 14 (apoptosis facilitator)
chr12_+_12202785 1.20 ENST00000586576.1
ENST00000464885.2
BCL2-like 14 (apoptosis facilitator)
chr2_+_219247021 1.19 ENST00000539932.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr8_+_104831554 1.18 ENST00000408894.2
regulating synaptic membrane exocytosis 2
chr15_-_43559055 1.16 ENST00000220420.5
ENST00000349114.4
transglutaminase 5
chr1_+_40840320 1.14 ENST00000372708.1
small ArfGAP2
chr11_+_129685707 1.14 ENST00000281441.3
transmembrane protein 45B
chr19_+_859425 1.13 ENST00000327726.6
complement factor D (adipsin)
chr22_-_31688381 1.10 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr1_+_147013182 1.05 ENST00000234739.3
B-cell CLL/lymphoma 9
chr6_+_167738569 1.04 ENST00000239587.5
tubulin tyrosine ligase-like family, member 2
chr1_-_1009683 1.04 ENST00000453464.2
ring finger protein 223
chr16_-_81110683 1.04 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
chromosome 16 open reading frame 46
chr14_-_76447494 1.03 ENST00000238682.3
transforming growth factor, beta 3
chr11_+_61447845 1.03 ENST00000257215.5
diacylglycerol lipase, alpha
chr11_+_65266507 1.02 ENST00000544868.1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr6_-_13487825 1.02 ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr16_+_53133070 1.02 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr11_-_76155700 1.01 ENST00000572035.1
RP11-111M22.3
chr11_-_114271139 1.00 ENST00000325636.4
chromosome 11 open reading frame 71
chr15_+_67547163 0.98 ENST00000335894.4
IQ motif containing H
chr19_+_859654 0.98 ENST00000592860.1
complement factor D (adipsin)
chr5_+_98104978 0.97 ENST00000308234.7
repulsive guidance molecule family member b
chr12_-_107380910 0.97 ENST00000392830.2
ENST00000240050.4
MTERF domain containing 3
chr1_+_155099927 0.97 ENST00000368407.3
ephrin-A1
chr6_+_131894284 0.96 ENST00000368087.3
ENST00000356962.2
arginase 1
chr10_+_695888 0.96 ENST00000441152.2
proline rich 26
chr4_+_74735102 0.94 ENST00000395761.3
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr17_+_76311791 0.94 ENST00000586321.1
AC061992.2
chr11_-_133826852 0.93 ENST00000533871.2
ENST00000321016.8
immunoglobulin superfamily, member 9B
chr15_-_52030293 0.92 ENST00000560491.1
ENST00000267838.3
LysM, putative peptidoglycan-binding, domain containing 2
chr2_-_152146385 0.92 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr3_-_46505137 0.91 ENST00000426532.2
ENST00000415180.1
lactotransferrin
chr12_-_107380846 0.91 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERF domain containing 3
chr14_-_65569244 0.90 ENST00000557277.1
ENST00000556892.1
MYC associated factor X
chr1_-_115124257 0.89 ENST00000369541.3
breast carcinoma amplified sequence 2
chr6_-_154751629 0.88 ENST00000424998.1
CNKSR family member 3
chr1_-_44818599 0.88 ENST00000537474.1
ERI1 exoribonuclease family member 3
chr12_-_91576429 0.88 ENST00000552145.1
ENST00000546745.1
decorin
chr11_-_44972476 0.87 ENST00000527685.1
ENST00000308212.5
tumor protein p53 inducible protein 11
chr2_-_61697862 0.86 ENST00000398571.2
ubiquitin specific peptidase 34
chr6_-_84937314 0.85 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr3_-_146213722 0.84 ENST00000336685.2
ENST00000489015.1
phospholipid scramblase 2
chr12_+_58148842 0.84 ENST00000266643.5
membrane-associated ring finger (C3HC4) 9
chr22_-_31688431 0.83 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
phosphoinositide-3-kinase interacting protein 1
chr22_-_24110063 0.83 ENST00000520222.1
ENST00000401675.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chrX_-_19689106 0.83 ENST00000379716.1
SH3-domain kinase binding protein 1
chr18_-_30050395 0.82 ENST00000269209.6
ENST00000399218.4
GRB2 associated, regulator of MAPK1
chr20_-_271009 0.82 ENST00000382369.5
chromosome 20 open reading frame 96
chr14_+_32546274 0.82 ENST00000396582.2
Rho GTPase activating protein 5
chr3_-_52443799 0.80 ENST00000470173.1
ENST00000296288.5
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr4_+_160188889 0.79 ENST00000264431.4
Rap guanine nucleotide exchange factor (GEF) 2
chr3_-_49466686 0.78 ENST00000273598.3
ENST00000436744.2
nicolin 1
chr2_-_40679186 0.78 ENST00000406785.2
solute carrier family 8 (sodium/calcium exchanger), member 1
chr15_+_60296421 0.78 ENST00000396057.4
forkhead box B1
chr17_+_58755184 0.78 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr17_-_42452063 0.78 ENST00000588098.1
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr2_+_217498105 0.77 ENST00000233809.4
insulin-like growth factor binding protein 2, 36kDa
chr3_-_61237050 0.77 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
fragile histidine triad
chrX_-_10645773 0.76 ENST00000453318.2
midline 1 (Opitz/BBB syndrome)
chr1_+_174843548 0.74 ENST00000478442.1
ENST00000465412.1
RAB GTPase activating protein 1-like
chr12_+_32112340 0.73 ENST00000540924.1
ENST00000312561.4
KIAA1551
chr19_-_10213335 0.73 ENST00000592641.1
ENST00000253109.4
angiopoietin-like 6
chr17_-_20370847 0.72 ENST00000423676.3
ENST00000324290.5
lectin, galactoside-binding, soluble, 9B
chr1_+_27114418 0.72 ENST00000078527.4
phosphatidylinositol glycan anchor biosynthesis, class V
chr11_-_76155618 0.72 ENST00000530759.1
RP11-111M22.3
chr1_+_26146397 0.70 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
mitochondrial fission regulator 1-like
chr19_+_3721719 0.70 ENST00000589378.1
ENST00000382008.3
tight junction protein 3
chr5_+_74807581 0.70 ENST00000241436.4
ENST00000352007.5
polymerase (DNA directed) kappa
chr3_+_142315225 0.70 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
plastin 1
chr16_-_88717482 0.69 ENST00000261623.3
cytochrome b-245, alpha polypeptide
chr21_+_25801041 0.69 ENST00000453784.2
ENST00000423581.1
AP000476.1
chrX_+_18443703 0.69 ENST00000379996.3
cyclin-dependent kinase-like 5
chr2_-_175869936 0.68 ENST00000409900.3
chimerin 1
chr4_-_89619386 0.67 ENST00000323061.5
nucleosome assembly protein 1-like 5
chr1_+_26146674 0.66 ENST00000525713.1
ENST00000374301.3
mitochondrial fission regulator 1-like
chr16_-_88717423 0.66 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
cytochrome b-245, alpha polypeptide
chr17_-_9929581 0.66 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chr17_+_25958174 0.66 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chr10_-_65028938 0.66 ENST00000402544.1
jumonji domain containing 1C
chr19_+_1000418 0.66 ENST00000234389.3
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr7_+_107110488 0.65 ENST00000304402.4
G protein-coupled receptor 22
chr12_-_10151773 0.65 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr22_+_35776828 0.63 ENST00000216117.8
heme oxygenase (decycling) 1
chr17_-_1553346 0.62 ENST00000301336.6
Rab interacting lysosomal protein
chr9_-_35815013 0.62 ENST00000259667.5
histidine triad nucleotide binding protein 2
chr5_+_140207536 0.62 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr14_-_20881579 0.62 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
telomerase-associated protein 1
chr8_+_28351707 0.61 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
frizzled family receptor 3
chr15_-_83316087 0.61 ENST00000568757.1
cytoplasmic polyadenylation element binding protein 1
chr10_-_65028817 0.60 ENST00000542921.1
jumonji domain containing 1C
chr10_-_120355149 0.60 ENST00000239032.2
prolactin releasing hormone receptor
chr13_+_42031679 0.59 ENST00000379359.3
regulator of cell cycle
chr2_+_74648848 0.59 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WD repeat domain 54
chr4_+_154622652 0.59 ENST00000260010.6
toll-like receptor 2
chr19_+_50529212 0.59 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
zinc finger protein 473
chr5_-_34043310 0.58 ENST00000231338.7
C1q and tumor necrosis factor related protein 3
chr9_-_117150303 0.58 ENST00000312033.3
AT-hook transcription factor
chr12_-_56120838 0.57 ENST00000548160.1
CD63 molecule
chr12_-_81763127 0.57 ENST00000541017.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr9_+_134378289 0.56 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
protein-O-mannosyltransferase 1
chr8_-_27457494 0.56 ENST00000521770.1
clusterin
chr6_+_30295036 0.56 ENST00000376659.5
ENST00000428555.1
tripartite motif containing 39
chr5_-_145562147 0.55 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
leucyl-tRNA synthetase
chr4_+_108745711 0.55 ENST00000394684.4
sphingomyelin synthase 2
chr17_+_76356516 0.55 ENST00000592569.1
RP11-806H10.4
chr6_+_108487245 0.55 ENST00000368986.4
nuclear receptor subfamily 2, group E, member 1
chr19_+_50528971 0.55 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
zinc finger protein 473
chr22_-_41215328 0.54 ENST00000434185.1
ENST00000435456.2
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr19_-_36236292 0.53 ENST00000378975.3
ENST00000412391.2
ENST00000292879.5
U2 small nuclear RNA auxiliary factor 1-like 4
chr12_-_81763184 0.53 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr1_+_32716840 0.53 ENST00000336890.5
lymphocyte-specific protein tyrosine kinase
chr5_+_56469843 0.53 ENST00000514387.2
GC-rich promoter binding protein 1
chr6_+_160221293 0.52 ENST00000610273.1
ENST00000392167.3
poly(A)-specific ribonuclease (PARN)-like domain containing 1
chr7_-_91875358 0.51 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1, ankyrin repeat containing
chr12_-_91348949 0.50 ENST00000358859.2
coiled-coil glutamate-rich protein 1
chr20_+_2517253 0.50 ENST00000358864.1
transmembrane channel-like 2
chr8_-_72268968 0.49 ENST00000388740.3
eyes absent homolog 1 (Drosophila)
chr4_+_26322185 0.49 ENST00000361572.6
recombination signal binding protein for immunoglobulin kappa J region
chr3_+_185000729 0.48 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
mitogen-activated protein kinase kinase kinase 13
chr6_+_127588020 0.48 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
ring finger protein 146
chr19_+_44081344 0.47 ENST00000599207.1
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chrX_+_129473859 0.47 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr6_+_30294612 0.47 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
tripartite motif containing 39

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.9 2.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.8 2.5 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.6 2.3 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 1.6 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.5 1.5 GO:0055073 cadmium ion homeostasis(GO:0055073) divalent metal ion export(GO:0070839)
0.5 4.8 GO:0015889 cobalamin transport(GO:0015889)
0.5 3.3 GO:0018879 biphenyl metabolic process(GO:0018879)
0.4 2.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.4 1.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.4 1.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4 1.5 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3 2.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.3 1.0 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.3 1.0 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.3 1.9 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 0.9 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 0.9 GO:1900159 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.3 6.6 GO:0007220 Notch receptor processing(GO:0007220)
0.3 0.8 GO:0007412 axon target recognition(GO:0007412)
0.3 1.0 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.2 1.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 3.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 0.7 GO:0043132 coenzyme A transport(GO:0015880) FAD transport(GO:0015883) coenzyme A transmembrane transport(GO:0035349) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.2 1.7 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2 1.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 0.6 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.2 0.6 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.2 0.2 GO:0061009 common bile duct development(GO:0061009)
0.2 0.6 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2 0.8 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 0.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 0.6 GO:0032289 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 1.4 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.2 1.0 GO:1902896 terminal web assembly(GO:1902896)
0.2 0.6 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.2 0.9 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.2 0.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.5 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.2 0.5 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 1.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 4.9 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.2 2.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 1.0 GO:0014028 notochord formation(GO:0014028)
0.2 5.3 GO:0010842 retina layer formation(GO:0010842)
0.1 1.9 GO:0015866 ADP transport(GO:0015866)
0.1 1.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 3.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 10.6 GO:0007602 phototransduction(GO:0007602)
0.1 0.6 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 3.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.8 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.4 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.6 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.6 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.5 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 3.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.3 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 1.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.6 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 13.1 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 1.8 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 0.6 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 2.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 1.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.1 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 2.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.5 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 1.9 GO:0030033 microvillus assembly(GO:0030033)
0.1 2.8 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.4 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 1.6 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.2 GO:2000078 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 0.2 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.1 0.3 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.9 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 2.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.4 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.2 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.6 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.5 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 1.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.4 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 1.0 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.5 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 1.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 1.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.5 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.6 GO:0015871 choline transport(GO:0015871)
0.0 0.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.2 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.9 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 1.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.7 GO:0030220 platelet formation(GO:0030220)
0.0 0.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.5 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 3.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0034378 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) chylomicron assembly(GO:0034378)
0.0 0.4 GO:0055123 digestive system development(GO:0055123)
0.0 0.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.0 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 2.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.7 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066) regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.0 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.0 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0021510 spinal cord development(GO:0021510)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.6 6.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.4 26.8 GO:0030286 dynein complex(GO:0030286)
0.3 2.5 GO:0044294 dendritic growth cone(GO:0044294)
0.3 0.8 GO:1902636 kinociliary basal body(GO:1902636)
0.2 0.6 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 1.3 GO:0044326 dendritic spine neck(GO:0044326)
0.2 1.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 0.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 4.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 4.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.0 GO:1990357 terminal web(GO:1990357)
0.1 0.7 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.9 GO:0043196 varicosity(GO:0043196)
0.1 0.9 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 1.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 2.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 4.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 1.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 2.1 GO:0032982 myosin filament(GO:0032982)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 1.3 GO:0032590 dendrite membrane(GO:0032590)
0.1 5.2 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 6.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 3.8 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 10.9 GO:0005929 cilium(GO:0005929)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 3.1 GO:0001650 fibrillar center(GO:0001650)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 4.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 1.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 26.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.6 1.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5 1.5 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.5 2.7 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.5 2.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 4.8 GO:0031419 cobalamin binding(GO:0031419)
0.4 4.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.4 2.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.3 1.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 1.6 GO:0097001 ceramide binding(GO:0097001)
0.3 0.8 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 1.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 1.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 5.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 0.7 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) FAD transmembrane transporter activity(GO:0015230) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 3.5 GO:0003796 lysozyme activity(GO:0003796)
0.2 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.8 GO:0070051 fibrinogen binding(GO:0070051)
0.2 3.3 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.6 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.2 0.8 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 0.8 GO:0002046 opsin binding(GO:0002046)
0.2 2.0 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.7 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 1.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.7 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.4 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 3.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 1.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 2.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 2.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 2.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.8 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 3.9 GO:0030552 cAMP binding(GO:0030552)
0.1 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.3 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.9 GO:0000150 recombinase activity(GO:0000150)
0.1 1.1 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.4 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 1.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 2.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 0.6 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.9 GO:0016594 glycine binding(GO:0016594)
0.1 0.3 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.0 1.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 4.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0031730 CCR1 chemokine receptor binding(GO:0031726) CCR5 chemokine receptor binding(GO:0031730)
0.0 0.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 2.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 2.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0019864 IgG binding(GO:0019864)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.9 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.0 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 3.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 1.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.6 GO:0030295 protein kinase activator activity(GO:0030295)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 6.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 2.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.9 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.4 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 5.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 4.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.2 5.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 2.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 3.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 3.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 7.6 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 3.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.6 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors