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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TBX3

Z-value: 0.46

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Transcription factors associated with TBX3

Gene Symbol Gene ID Gene Info
TBX3
ENSG00000135111.10 T-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX3hg19_v2_chr12_-_115121962_115121987-0.134.8e-01Click!

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_56725952 1.56 ENST00000371168.3
C20orf85
chromosome 20 open reading frame 85
chr6_+_52285131 0.58 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr22_+_24891210 0.57 ENST00000382760.2
UPB1
ureidopropionase, beta
chr7_+_76751926 0.56 ENST00000285871.4
ENST00000431197.1
CCDC146
coiled-coil domain containing 146
chr12_+_12223867 0.56 ENST00000308721.5
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr7_-_138386097 0.55 ENST00000421622.1
SVOPL
SVOP-like
chr11_-_1629693 0.54 ENST00000399685.1
KRTAP5-3
keratin associated protein 5-3
chr19_-_55677920 0.51 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr16_+_58283814 0.51 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr14_-_106642049 0.46 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr2_-_217560248 0.41 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr6_+_52285046 0.40 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr17_+_26800756 0.38 ENST00000537681.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr8_-_12668962 0.37 ENST00000534827.1
RP11-252C15.1
RP11-252C15.1
chr6_-_134861089 0.36 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr6_-_52668605 0.36 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chrX_+_65382433 0.36 ENST00000374727.3
HEPH
hephaestin
chr4_-_190948409 0.36 ENST00000504750.1
ENST00000378763.1
FRG2
FSHD region gene 2
chr1_+_162351503 0.34 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chrX_+_140984021 0.33 ENST00000409007.1
MAGEC3
melanoma antigen family C, 3
chr5_+_35617940 0.33 ENST00000282469.6
ENST00000509059.1
ENST00000356031.3
ENST00000510777.1
SPEF2
sperm flagellar 2
chr14_-_21270561 0.33 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr19_+_1077393 0.33 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr19_-_7766991 0.31 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr19_-_9092018 0.31 ENST00000397910.4
MUC16
mucin 16, cell surface associated
chr3_+_133118839 0.31 ENST00000302334.2
BFSP2
beaded filament structural protein 2, phakinin
chr1_-_183560011 0.29 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr14_-_21270995 0.28 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr2_-_217559517 0.27 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr11_+_71238313 0.27 ENST00000398536.4
KRTAP5-7
keratin associated protein 5-7
chr3_-_46068969 0.27 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr1_-_242612779 0.26 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr22_+_23237555 0.25 ENST00000390321.2
IGLC1
immunoglobulin lambda constant 1 (Mcg marker)
chr4_-_84030996 0.25 ENST00000411416.2
PLAC8
placenta-specific 8
chr12_+_129028500 0.24 ENST00000315208.8
TMEM132C
transmembrane protein 132C
chr10_-_1071796 0.23 ENST00000277517.1
IDI2
isopentenyl-diphosphate delta isomerase 2
chr12_+_124155652 0.22 ENST00000426174.2
ENST00000303372.5
TCTN2
tectonic family member 2
chrX_+_140968348 0.21 ENST00000536088.1
ENST00000443323.2
MAGEC3
melanoma antigen family C, 3
chr10_-_71176623 0.21 ENST00000373306.4
TACR2
tachykinin receptor 2
chr11_+_34643600 0.21 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr4_+_120056939 0.21 ENST00000307128.5
MYOZ2
myozenin 2
chr2_-_89513402 0.21 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr8_+_79578282 0.21 ENST00000263849.4
ZC2HC1A
zinc finger, C2HC-type containing 1A
chr10_-_7513904 0.21 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr18_+_48918368 0.21 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
RP11-267C16.1
chr6_-_29324054 0.20 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr11_+_27062272 0.20 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr14_+_96505659 0.20 ENST00000555004.1
C14orf132
chromosome 14 open reading frame 132
chr11_+_27062502 0.19 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_-_21239978 0.19 ENST00000380222.2
IFNA14
interferon, alpha 14
chrX_+_65382381 0.19 ENST00000519389.1
HEPH
hephaestin
chr7_+_98476095 0.19 ENST00000359863.4
ENST00000355540.3
TRRAP
transformation/transcription domain-associated protein
chr3_-_42452050 0.19 ENST00000441172.1
ENST00000287748.3
LYZL4
lysozyme-like 4
chr7_-_112726393 0.19 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85
G protein-coupled receptor 85
chr19_-_10491130 0.19 ENST00000530829.1
ENST00000529370.1
TYK2
tyrosine kinase 2
chr19_+_56717283 0.18 ENST00000376267.1
ZSCAN5C
zinc finger and SCAN domain containing 5C
chr2_-_24149977 0.18 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr19_-_5567842 0.17 ENST00000587632.1
TINCR
tissue differentiation-inducing non-protein coding RNA
chr19_-_6333614 0.16 ENST00000301452.4
ACER1
alkaline ceramidase 1
chr11_+_18433840 0.16 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr3_+_118866222 0.16 ENST00000490594.1
RP11-484M3.5
Uncharacterized protein
chr20_+_2795626 0.16 ENST00000603872.1
ENST00000380589.4
C20orf141
chromosome 20 open reading frame 141
chr7_-_99381798 0.16 ENST00000415003.1
ENST00000354593.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr14_-_74417096 0.15 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chrX_+_135570046 0.15 ENST00000370648.3
BRS3
bombesin-like receptor 3
chr11_-_73689037 0.15 ENST00000544615.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr1_+_47489240 0.15 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr11_+_65190245 0.15 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr1_+_167599330 0.15 ENST00000367854.3
ENST00000361496.3
RCSD1
RCSD domain containing 1
chr22_+_45680822 0.15 ENST00000216211.4
ENST00000396082.2
UPK3A
uroplakin 3A
chr10_+_32856764 0.15 ENST00000375030.2
ENST00000375028.3
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr5_+_35618058 0.14 ENST00000440995.2
SPEF2
sperm flagellar 2
chr7_+_150264365 0.14 ENST00000255945.2
ENST00000461940.1
GIMAP4
GTPase, IMAP family member 4
chr3_+_52454971 0.14 ENST00000465863.1
PHF7
PHD finger protein 7
chr14_+_74111578 0.14 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chr2_-_89266286 0.14 ENST00000464162.1
IGKV1-6
immunoglobulin kappa variable 1-6
chr7_-_99381884 0.14 ENST00000336411.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr12_-_88535747 0.13 ENST00000309041.7
CEP290
centrosomal protein 290kDa
chr17_-_55822653 0.13 ENST00000299415.2
AC007431.1
coiled-coil domain containing 182
chr14_-_92333873 0.13 ENST00000435962.2
TC2N
tandem C2 domains, nuclear
chr1_-_47131521 0.13 ENST00000542495.1
ENST00000532925.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr14_+_74416989 0.13 ENST00000334571.2
ENST00000554920.1
COQ6
coenzyme Q6 monooxygenase
chr17_+_43861680 0.13 ENST00000314537.5
CRHR1
corticotropin releasing hormone receptor 1
chr19_-_55691614 0.12 ENST00000592470.1
ENST00000354308.3
SYT5
synaptotagmin V
chr14_-_24911971 0.12 ENST00000555365.1
ENST00000399395.3
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr18_+_63418068 0.12 ENST00000397968.2
CDH7
cadherin 7, type 2
chr11_+_7506713 0.12 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr11_-_122932730 0.12 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8
heat shock 70kDa protein 8
chr1_+_171217622 0.12 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr19_-_55691472 0.12 ENST00000537500.1
SYT5
synaptotagmin V
chr19_+_19322758 0.12 ENST00000252575.6
NCAN
neurocan
chr6_-_110736742 0.11 ENST00000368924.3
ENST00000368923.3
DDO
D-aspartate oxidase
chr7_-_150721570 0.11 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chr1_-_182921119 0.11 ENST00000423786.1
SHCBP1L
SHC SH2-domain binding protein 1-like
chr9_-_71155783 0.11 ENST00000377311.3
TMEM252
transmembrane protein 252
chr2_+_89184868 0.10 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr9_+_273038 0.10 ENST00000487230.1
ENST00000469391.1
DOCK8
dedicator of cytokinesis 8
chr19_+_58281014 0.10 ENST00000391702.3
ENST00000598885.1
ENST00000598183.1
ENST00000396154.2
ENST00000599802.1
ENST00000396150.4
ZNF586
zinc finger protein 586
chr3_-_46069223 0.10 ENST00000309285.3
XCR1
chemokine (C motif) receptor 1
chr20_-_1472029 0.10 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr19_-_51530916 0.10 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr6_-_52628271 0.10 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr21_+_25801041 0.10 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr4_+_123300664 0.10 ENST00000388725.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chrX_-_101726732 0.10 ENST00000457521.2
ENST00000412230.2
ENST00000453326.2
NXF2B
TCP11X2
nuclear RNA export factor 2B
t-complex 11 family, X-linked 2
chr13_+_73356197 0.10 ENST00000326291.6
PIBF1
progesterone immunomodulatory binding factor 1
chr6_+_140175987 0.10 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr6_-_33771757 0.10 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
MLN
motilin
chrX_+_101470280 0.10 ENST00000395088.2
ENST00000330252.5
ENST00000333110.5
NXF2
TCP11X1
nuclear RNA export factor 2
t-complex 11 family, X-linked 1
chr1_-_154461642 0.10 ENST00000555188.1
SHE
Src homology 2 domain containing E
chr17_+_20483037 0.10 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr1_-_153283194 0.09 ENST00000290722.1
PGLYRP3
peptidoglycan recognition protein 3
chr7_-_144107320 0.09 ENST00000483238.1
ENST00000467773.1
NOBOX
NOBOX oogenesis homeobox
chr10_-_44144152 0.09 ENST00000395797.1
ZNF32
zinc finger protein 32
chr5_+_175740083 0.09 ENST00000332772.4
SIMC1
SUMO-interacting motifs containing 1
chr17_-_26220366 0.09 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr22_+_41258250 0.09 ENST00000544094.1
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr10_+_94608245 0.09 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr2_+_66666432 0.09 ENST00000495021.2
MEIS1
Meis homeobox 1
chr14_-_24912047 0.09 ENST00000553930.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr9_+_134378289 0.09 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
POMT1
protein-O-mannosyltransferase 1
chr19_-_51531210 0.09 ENST00000391804.3
KLK11
kallikrein-related peptidase 11
chr6_+_32821924 0.09 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr5_+_150040403 0.08 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr4_+_155484155 0.08 ENST00000509493.1
FGB
fibrinogen beta chain
chr12_-_88535842 0.08 ENST00000550962.1
ENST00000552810.1
CEP290
centrosomal protein 290kDa
chr21_-_43346790 0.08 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr19_-_51531272 0.08 ENST00000319720.7
KLK11
kallikrein-related peptidase 11
chr11_+_71249071 0.08 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr17_+_27895609 0.08 ENST00000581411.2
ENST00000301057.7
TP53I13
tumor protein p53 inducible protein 13
chr12_+_7169887 0.08 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr10_-_14996321 0.08 ENST00000378289.4
DCLRE1C
DNA cross-link repair 1C
chr3_-_45838011 0.08 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr22_+_27017921 0.08 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr1_-_51810778 0.07 ENST00000413473.2
ENST00000401051.3
ENST00000527205.1
TTC39A
tetratricopeptide repeat domain 39A
chr19_-_47735918 0.07 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr4_+_187148556 0.07 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chrX_+_149887090 0.07 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr1_-_38230738 0.07 ENST00000427468.2
ENST00000373048.4
ENST00000319637.6
EPHA10
EPH receptor A10
chr9_+_130186653 0.07 ENST00000342483.5
ENST00000543471.1
ZNF79
zinc finger protein 79
chr17_-_60883993 0.07 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr1_+_172628154 0.07 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr19_+_42724423 0.07 ENST00000301215.3
ENST00000597945.1
ZNF526
zinc finger protein 526
chr12_-_8815404 0.07 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr6_-_33385655 0.07 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr11_+_19138670 0.07 ENST00000446113.2
ENST00000399351.3
ZDHHC13
zinc finger, DHHC-type containing 13
chr11_+_20044600 0.06 ENST00000311043.8
NAV2
neuron navigator 2
chr6_+_6588316 0.06 ENST00000379953.2
LY86
lymphocyte antigen 86
chr16_+_83932684 0.06 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr2_+_234580499 0.06 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr6_+_31514622 0.06 ENST00000376146.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr12_-_70093190 0.06 ENST00000330891.5
BEST3
bestrophin 3
chr2_-_27545921 0.06 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
MPV17
MpV17 mitochondrial inner membrane protein
chr2_+_234580525 0.06 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr9_+_71394945 0.06 ENST00000394264.3
FAM122A
family with sequence similarity 122A
chr11_-_10590238 0.06 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr7_-_150675372 0.06 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_-_104916034 0.06 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr2_+_162101247 0.06 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr1_-_13219581 0.05 ENST00000423177.1
PRAMEF26
PRAME family member 26
chrX_+_46306714 0.05 ENST00000298190.6
ENST00000377919.2
ENST00000476762.1
ENST00000478600.1
KRBOX4
KRAB box domain containing 4
chr4_-_6202291 0.05 ENST00000282924.5
JAKMIP1
janus kinase and microtubule interacting protein 1
chr11_+_196738 0.05 ENST00000325113.4
ENST00000342593.5
ODF3
outer dense fiber of sperm tails 3
chrX_+_22291065 0.05 ENST00000323684.1
ZNF645
zinc finger protein 645
chr1_-_152552980 0.05 ENST00000368787.3
LCE3D
late cornified envelope 3D
chr1_-_101491319 0.05 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5
diphthamide biosynthesis 5
chr3_-_68981685 0.05 ENST00000495737.1
ENST00000295569.7
FAM19A4
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4
chr7_+_95401877 0.05 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr16_-_50913188 0.05 ENST00000569986.1
CTD-2034I21.1
CTD-2034I21.1
chr7_-_127255724 0.05 ENST00000463946.1
ENST00000341640.2
PAX4
paired box 4
chr11_+_71259466 0.05 ENST00000528743.2
KRTAP5-9
keratin associated protein 5-9
chr3_+_124223586 0.05 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr7_-_141673573 0.05 ENST00000547270.1
TAS2R38
taste receptor, type 2, member 38
chr1_-_212208842 0.05 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
INTS7
integrator complex subunit 7
chr6_-_55443958 0.05 ENST00000370850.2
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr9_+_35490101 0.05 ENST00000361226.3
RUSC2
RUN and SH3 domain containing 2
chr18_-_5544241 0.05 ENST00000341928.2
ENST00000540638.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr19_-_16682987 0.05 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
SLC35E1
solute carrier family 35, member E1
chr14_-_107283278 0.05 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr11_-_122931881 0.05 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chr19_-_51538118 0.05 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr12_+_133757995 0.05 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
ZNF268
zinc finger protein 268
chr19_+_41103063 0.05 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chr12_+_133758115 0.04 ENST00000541009.2
ENST00000592241.1
ZNF268
zinc finger protein 268
chr19_-_51538148 0.04 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr19_+_21265028 0.04 ENST00000291770.7
ZNF714
zinc finger protein 714
chr1_+_36396313 0.04 ENST00000324350.5
AGO3
argonaute RISC catalytic component 3
chrX_+_44703249 0.04 ENST00000339042.4
DUSP21
dual specificity phosphatase 21
chr3_+_122103014 0.04 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
FAM162A
family with sequence similarity 162, member A
chr4_+_155484103 0.04 ENST00000302068.4
FGB
fibrinogen beta chain
chr10_-_13523073 0.04 ENST00000440282.1
BEND7
BEN domain containing 7
chr18_+_5238055 0.04 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
LINC00667
long intergenic non-protein coding RNA 667
chr14_+_67291158 0.04 ENST00000555456.1
GPHN
gephyrin
chr4_-_108641608 0.04 ENST00000265174.4
PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr12_-_7848364 0.04 ENST00000329913.3
GDF3
growth differentiation factor 3
chr2_+_90153696 0.04 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr3_+_108541545 0.04 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr14_-_74416829 0.04 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr6_-_31514333 0.03 ENST00000376151.4
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr11_-_33744256 0.03 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59
CD59 molecule, complement regulatory protein

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.6 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.3 GO:0036378 alkaloid catabolic process(GO:0009822) calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 0.3 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.2 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.0 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 1.0 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.3 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.0 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.0 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.0 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis